Prof Graham Rook

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Personal Profile

Name: Graham Rook Email: g.rook@ucl.ac.uk
Title: Prof Tel: 07808402907
Department: Research Department of Infection Fax:
Position: Emeritus Professor of Medical Microbiology Address: , , ,
Research Domain: Global Health, Infection, Immunology & Inflammation, Personalised Medicine, Populations & Lifelong Health Web Page: Personal Web Page

Profile

Research Description

1) Tuberculosis
The dominant theme was initially the immunopathology of tuberculosis, with a major emphasis on the interactions of IL-4 and IL-4?2 with mycobacterial infections. This broadened to include the endocrinology and immunoendocrinology of TB. His approach is interdisciplinary, with emphasis on integrative physiology leading to publications on endocrinology, immunology, microbiology, neuroscience and most recently on depression and its links to inflammatory cytokines.

2) Microorganisms and Darwinian medicine.
The diseases that are increasing in incidence in developed countries, (allergies, autoimmune disease and inflammatory bowel disease), are a major research interest, particularly the role that changing exposure to environmental microorganisms is playing in the accompanying dysfunction of regulatory T cells and antigen-presenting cells. This has led clinical trials and publications in the field of allergic disorders.

G.R. co-founded a biotech company (Silence Therapeutics plc.), and is co-inventor of more than 20 patents.


Research Activities

Microorganisms and immunoregulation

Education Description

UCL Collaborators

Prof Tom Rademacher; Dr James Huggett; Prof Ali Zumla; Dr Mahdad Noursadeghi; Prof Timothy Mchugh

External Collaborators

Publications

    2014

    • Rook GA, Raison CL, Lowry CA (2014). Microbial "Old Friends", immunoregulation and socio-economic status.. Clin Exp Immunol, , - . doi:10.1111/cei.12269
    • Rook GA, Lowry CA, Raison CL (2014). Hygiene and other early childhood influences on the subsequent function of the immune system.. Brain Res, , - . doi:10.1016/j.brainres.2014.04.004

    2013

    • Rook GA, Lowry CA, Raison CL (2013). Microbial 'Old Friends', immunoregulation and stress resilience.. Evol Med Public Health, 2013(1), 46 - 64. doi:10.1093/emph/eot004
    • Rook GA, Raison CL, Lowry CA (2013). Childhood microbial experience, immunoregulation, inflammation and adult susceptibility to psychosocial stressors and depression in rich and poor countries.. Evol Med Public Health, 2013(1), 14 - 17. doi:10.1093/emph/eos005
    • Camacho F, Huggett J, Kim L, Infante JF, Lepore M, Perez V, Sarmiento ME, Rook G, Acosta A (2013). Phage display of functional αβ single-chain T-cell receptor molecules specific for CD1b:Ac₂SGL complexes from Mycobacterium tuberculosis-infected cells.. BMC Immunol, 14 Suppl 1, S2 - . doi:10.1186/1471-2172-14-S1-S2
    • Olivares N, Marquina B, Mata Espinoza D, Zatarain-Barron ZL, Espitia Pinzón C, Estrada I, Parada C, Collin M, Rook G, Hernandez-Pando R (2013). The protective effect of immunoglobulin in murine tuberculosis is dependent on IgG glycosylation.. Pathog Dis, , - . doi:10.1111/2049-632X.12069
    • Rook GA (2013). Regulation of the immune system by biodiversity from the natural environment: An ecosystem service essential to health.. Proc Natl Acad Sci U S A, , - . doi:10.1073/pnas.1313731110

    2012

    • Hale MW, Rook GA, Lowry CA (2012). Pathways underlying afferent signaling of bronchopulmonary immune activation to the central nervous system.. Chem Immunol Allergy, 98, 118 - 141. doi:10.1159/000336505
    • Luzina IG, Keegan AD, Heller NM, Rook GA, Shea-Donohue T, Atamas SP (2012). Regulation of inflammation by interleukin-4: a review of "alternatives".. J Leukoc Biol, 92(4), 753 - 764. doi:10.1189/jlb.0412214
    • Rook GA (2012). Hygiene hypothesis and autoimmune diseases.. Clin Rev Allergy Immunol, 42(1), 5 - 15. doi:10.1007/s12016-011-8285-8
    • Rook GA, Raison CL, Lowry CA (2012). Can we vaccinate against depression?. Drug Discov Today, 17(9-10), 451 - 458. doi:10.1016/j.drudis.2012.03.018
    • Barrios-Payán J, Saqui-Salces M, Jeyanathan M, Alcántara-Vazquez A, Castañon-Arreola M, Rook G, Hernandez-Pando R (2012). Extrapulmonary locations of mycobacterium tuberculosis DNA during latent infection.. J Infect Dis, 206(8), 1194 - 1205. doi:10.1093/infdis/jis381

    2011

    • Rook GA (2011). Hygiene and other early childhood influences on the subsequent function of the immune system.. Dig Dis, 29(2), 144 - 153. doi:10.1159/000323877
    • Rook GA, Dalgleish A (2011). Infection, immunoregulation, and cancer.. Immunol Rev, 240(1), 141 - 159. doi:10.1111/j.1600-065X.2010.00987.x
    • Abebe M, Kim L, Rook G, Aseffa A, Wassie L, Zewdie M, Zumla A, Engers H, Andersen P, Doherty TM (2011). Modulation of cell death by M. tuberculosis as a strategy for pathogen survival.. Clin Dev Immunol, 2011, 678570 - . doi:10.1155/2011/678570
    • Rook GA, Lowry CA, Raison CL (2011). Lymphocytes in neuroprotection, cognition and emotion: is intolerance really the answer?. Brain Behav Immun, 25(4), 591 - 601. doi:10.1016/j.bbi.2010.12.005
    • Le Bert N, Chain BM, Rook G, Noursadeghi M (2011). DC priming by M. vaccae inhibits Th2 responses in contrast to specific TLR2 priming and is associated with selective activation of the CREB pathway.. PLoS One, 6(4), e18346 - . doi:10.1371/journal.pone.0018346
    • Mendez A, Hernandez-Pando R, Contreras S, Aguilar D, Rook GA (2011). CCL2, CCL18 and sIL-4R in renal, meningeal and pulmonary TB; a 2 year study of patients and contacts.. Tuberculosis (Edinb), 91(2), 140 - 145. doi:10.1016/j.tube.2010.12.008

    2010

    • Rook GAW (2010). Evolved dependence of the human immune system on microbial Old Friends..
    • Raison CL, Lowry CA, Rook GA (2010). Inflammation, sanitation, and consternation: loss of contact with coevolved, tolerogenic microorganisms and the pathophysiology and treatment of major depression.. Arch Gen Psychiatry, 67(12), 1211 - 1224. doi:10.1001/archgenpsychiatry.2010.161
    • Abebe M, Doherty TM, Wassie L, Aseffa A, Bobosha K, Demissie A, Zewdie M, Engers H, Andersen P, Kim L, Huggett J, Rook G, Yamuah LK, Zumla A, VACSEL study group (2010). Expression of apoptosis-related genes in an Ethiopian cohort study correlates with tuberculosis clinical status.. Eur J Immunol, 40(1), 291 - 301. doi:10.1002/eji.200939856
    • Rakotosamimanana N, Raharimanga V, Andriamandimby SF, Soares JL, Doherty TM, Ratsitorahina M, Ramarokoto H, Zumla A, Huggett J, Rook G, Richard V, Gicquel B, Rasolofo-Razanamparany V, VACSEL/VACSIS Study Group (2010). Variation in gamma interferon responses to different infecting strains of Mycobacterium tuberculosis in acid-fast bacillus smear-positive patients and household contacts in Antananarivo, Madagascar.. Clin Vaccine Immunol, 17(7), 1094 - 1103. doi:10.1128/CVI.00049-10
    • Pooran A, Booth H, Miller RF, Scott G, Badri M, Huggett JF, Rook G, Zumla A, Dheda K (2010). Different screening strategies (single or dual) for the diagnosis of suspected latent tuberculosis: a cost effectiveness analysis.. BMC Pulm Med, 10, 7 - . doi:10.1186/1471-2466-10-7
    • Rook GA (2010). 99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: darwinian medicine and the 'hygiene' or 'old friends' hypothesis.. Clin Exp Immunol, 160(1), 70 - 79. doi:10.1111/j.1365-2249.2010.04133.x

    2009

    • Armelagos GJ, Harper KN, Campbell AR, Rook GA (2009). The Paleolithic Disease-scape, the Hygiene Hypothesis, and the Second Epidemiological Transition..
    • Rook GAW, Lowry CA (2009). The hygiene hypothesis and affective and anxiety disorders. In Rook GAW (Ed.), The Hygiene Hypothesis and Darwinian Medicine (pp. - ). : Birkhauser.
    • Rook GA (2009). Review series on helminths, immune modulation and the hygiene hypothesis: the broader implications of the hygiene hypothesis.. Immunology, 126(1), 3 - 11. doi:10.1111/j.1365-2567.2008.03007.x
    • Witt N, Rodger G, Vandesompele J, Benes V, Zumla A, Rook GA, Huggett JF (2009). An assessment of air as a source of DNA contamination encountered when performing PCR.. J Biomol Tech, 20(5), 236 - 240.
    • Rook GAW (2009). The changing microbial environment, Darwinian Medicine and the hygiene hypothesis. In (Ed.), The hygiene hypothesis and Darwinian Medicine (pp. - ). : Birkhäuser.
    • Churchyard GJ, Kaplan G, Fallows D, Wallis RS, Onyebujoh P, Rook GA (2009). Advances in immunotherapy for tuberculosis treatment.. Clin Chest Med, 30(4), 769 - ix. doi:10.1016/j.ccm.2009.08.009
    • Rook GAW, Doherty TM (2009). Host susceptibility and resistance to Mycobacterium tuberculosis; Genetic, Neuroendocrine, and acquired factors. In Schaaf HS, Zumla A (Ed.), Tuberculosis (pp. - ). : W B Saunders Co.
    • Rook GAW (2009). The changing microbial environment, Darwinian Medicine and the hygiene hypothesis. In (Ed.), The hygiene hypothesis and Darwinian Medicine (pp. - ). : Birkhäuser.

    2008

    • Hernandez-Pando R, Aguilar D, Orozco H, Cortez Y, Brunet LR, Rook GA (2008). Orally Administered Mycobacterium vaccae Modulates Expression of Immunoregulatory Molecules in BALB/c Mice with Pulmonary Tuberculosis. CLIN VACCINE IMMUNOL, 15(11), 1730 - 1736. doi:10.1128/CVI.00286-08
    • Rook GA (2008). The changing microbial environment and chronic inflammatory disorders.. Allergy Asthma Clin Immunol, 4(3), 117 - 124. doi:10.1186/1710-1492-4-3-117
    • Rook GAW (2008). The changing microbial environment and chronic inflammatory disorders. Allergy, Asthma and Clinical Immunology, 4, - . doi:10.2310/7480.2008.00013
    • Rook GAW, Lowry CA (2008). The hygiene hypothesis and psychiatric disorders. Trends in Immunology, 29, 150 - 158.
    • Davies PDO, Yew WW, Ganguly D, Davidow AL, Reichman LB, Dheda K, Rook GAW (2008). Smoking and tuberculosis: the epidemiological association and immunopathogenesis. Transactions of the Royal Society of Tropical Medicine and Hygiene, 100, 291 - 298. doi:10.1016/j.trstmh.2005.06.034
    • Dheda K, Chan JS, Lala S, Hugget JF, Zumla A, Rook G (2008). Gene expression of IL17 and IL23 in the lungs of patients with active tuberculosis.. Thorax, 63(6), 566 - 568.
    • Rook G, Witt N (2008). Probiotics and other organisms in allergy and autoimmune diseases. In Versalovic J, Wilson M (Ed.), Therapeutic microbiology: probiotics and related strategies (pp. 231 - 247). : ASM Press.
    • Rook GAW, Witt N (2008). Probiotics and other organisms in Allergy and Autoimmune Diseases. In Versalovic J, Wilson M (Ed.), Therapeutic microbiology (pp. - ). : Amer Society for Microbiology.
    • Pulimood AB, Peter S, Rook GAW, Donoghue HD (2008). In situ PCR for Mycobacterium tuberculosis in endoscopic mucosal biopsies of intestinal tuberculosis and Crohn disease. American Journal of Clinical Pathology, 129, 846 - 851.
    • Wassie L, Demissie A, Aseffa A, Abebe M, Yamuah L, Tilahun H, Petros B, Rook GAW, Zumla A, Andersen A, Doherty TM, VACSIS SG (2008). Ex vivo cytokine mRNA levels correlate with changing clinical status of Ethiopian TB patients and their contacts over time. PLoS ONE, 3, e1522 - .
    • Hernández-Pando R, Aguilar D, Orozco H, Cortez Y, Rosa Brunet L, Rook GAW (2008). Immunotherapeutic effect of oral Mycobacterium vaccae on pulmonary tuberculosis in BALB/c mice; modulation of expression of molecules involved in immunoregulation. Clinical and Vaccine Immunology, , - .

    2007

    • Rook GAW (2007). The hygiene hypothesis and the increamng prevalence of chronic inflammatory disorders. T ROY SOC TROP MED H, 101(11), 1072 - 1074. doi:10.1016/i.trstmh.2007.05.014
    • Lowry CA, Hollis JH, de Vries A, Pan B, Brunet LR, Hunt JR, Paton JF, van Kampen E, Knight DM, Evans AK, Rook GA, Lightman SL (2007). Identification of an immune-responsive mesolimbocortical serotonergic system: potential role in regulation of emotional behavior.. Neuroscience, 146(2), 756 - 772. doi:10.1016/j.neuroscience.2007.01.067
    • Rook GAW (2007). Th2 cytokines in susceptibility to tuberculosis. Current Molecular Medicine, 7(3), 327 - 337.
    • Rook GAW (2007). The hygiene hypothesis and the increasing prevalence of chronic inflammatory disorders. Transactions of the Royal Society of Tropical Medicine and Hygiene, 101, 1072 - 1074.
    • Rook GAW (2007). Endocrine and cytokine responses in humans with pulmonary tuberculosis. Brain, Behavior, and Immunity, 21(2), 169 - 170. doi:10.1016/j.bbi.2006.08.003
    • Rook GAW (2007). Stop TB: a long way to go, but new twists and turns in the science. Indian Journal of Medical Research, 125, 109 - 111.
    • Lala S, Dheda K, Chang JS, Huggett JF, Kim LU, Johnson MA, Rook GAW, Keshav S, Zumla A (2007). The pathogen recognition sensor, NOD2, is variably expressed in patients with pulmonary tuberculosis. BMC Infectious Diseases, 7, 96 - .
    • Rook GAW, Lowrie DB, Hernandez Pando R (2007). Immunotherapeutics for tuberculosis in experimental animals; is a common pathway activated by effective protocols. The Journal of Infectious Diseases, 196, 191 - 198.
    • Lowry CA, Hollis JH, de Vries A, Pan B, Brunet R, Hunt JR, Paton JE, van Kampen E, Knight DM, Evans AK, Rook GAW, Lightman SL (2007). Identification of an immune-responsive mesolimbocortical serotonergic system: potential in regulation of emotional behaviour. Neuroscience, 146(2), 756 - 772.
    • Dheda K, Pooran A, Pai M, Miller RF, Lesley K, Booth HL, Scott GM, Akbar AN, Zumla A, Rook GA (2007). Interpretation of Mycobacterium tuberculosis antigen-specific IFN-gamma release assays (T-SPOT.TB) and factors that may modulate test results. Journal of Infection, 55(2), 169 - 173.
    • Dheda K, Chang J, S H, J F K, L U J, M A Z, A R, G AW (2007). The stability of mRNA encoding IL-4 is increased in pulmonary tuberculosis, while stability of mRNA encoding the antagonistic splice variant, IL-4delta2, is not. Tuberculosis, 87, 237 - 241.
    • Burl S, Hill PC, Jeffries DJ, Holland MJ, Fox A, Lugos MD, Adegbola RA, Rook GA, Zumla A, McAdam KP, Brookes RH (2007). FOXP3 gene expression in a tuberculosis case contact study. Clinical and Experimental Immunology, [Epub ahead of p, - .
    • Rook GAW, Hamelmann E, Rosa Brunet L (2007). Mycobacteria and allergies. Immunobiology, 212(6), 461 - 473. doi:10.1016/j.imbio.2007.03.003

    2006

    • Ruddick JP, Evans A K N, D J L, S L Rook G, Lowry CA (2006). Tryptophan metabolism in the central nervous system: medical implications. Expert Reviews in Molecular Medicine, 8(20), 1 - 27.
    • Ruddick JP, Evans AK, Nutt DJ, Lightman SL, Rook GA, Lowry CA (2006). Tryptophan metabolism in the central nervous system: medical implications.. Expert Rev Mol Med, 8(20), 1 - 27. doi:10.1017/S1462399406000068
    • Guarner FB-S, R Brandtzaeg PG, H S M, P VE, W V, J W, J V R, G (2006). Mechanisms of disease: the hygiene hypothesis revisited. Nature Clinical Practice Gastroenterology and Hepatology, 3(5), 275 - 284.
    • Doherty TM, Rook G (2006). Progress and hindrances in tuberculosis vaccine development. The Lancet, 367, 947 - 949.
    • Berth-Jones J, Arkwright PD, Marasovic D, Savani N, Aldridge CR, Leech SN, Morgan C, Clark SM, Ogilvie S, Chopra S, Harper JI, Smith CH, Rook GAW, Friedmann PS (2006). Killed Mycobacterium vaccae suspension in children with moderate-to-severe atopic dermatitis: a randomized, double-blind, placebo-controlled trial. CLIN EXP ALLERGY, 36(9), 1115 - 1121.
    • Rook G, Dheda K, Zumla A (2006). Immune systems in developed and developing countries; implications for the design of vaccines that will work where BCG does not. Tuberculosis (Edinb), 86, 152 - 162.
    • Demissie A, Wassie L, Abebe M, Aseffa A, Rook G, Zumla A, Andersen P, Doherty TM (2006). The 6-kilodalton early secreted antigenic target-responsive, asymptomatic contacts of tuberculosis patients express elevated levels of interleukin-4 and reduced levels of gamma interferon. Infection and Immunity, 74(5), 2817 - 2822.
    • Demissie A, Leyten EM, Abebe M, Wassie L, Aseffa A, Abate G, Fletcher H, Owiafe P, Hill PC, Brookes R, Rook G, Zumla A, Arend SM, Klein M, Ottenhoff TH, Andersen PD, T M (2006). Recognition of stage-specific mycobacterial antigens differentiates between acute and latent infections with Mycobacterium tuberculosis. Clinical and Vaccine Immunology, 13(20), 179 - 186.
    • Berth-Jones J, Arkwright PD, Marasovic D, Savani N, Aldridge CR, Leech SN, Morgan C, Clark SM, Ogilvie S, Chopra S, Harper JI, Smith CH, Rook GAW, Friedmann PS (2006). Killed Mycobacterium vaccae suspension in children with moderate-to-severe atopic dermatitis: a randomized, double-blind, placebo-controlled trial. Clinical and Experimental Allergy, 36(9), 1115 - 1121.
    • Demissie A, Wassie L, Abebe M, Aseffa A, Rook G, Zumla A, Andersen P, Doherty TM, VACSEL Study Grp (2006). The 6-kilodalton early secreted antigenic target-responsive, asymptomatic contacts of tuberculosis patients express elevated levels of interleukin-4 and reduced levels of gamma interferon. INFECT IMMUN, 74(5), 2817 - 2822. doi:10.1128/IAI.75.5.2817-2822.2006
    • Chang J-S, Huggett JF, Dheda K, Kim LU, Zumla A, Rook G (2006). M. tuberculosis induces selective upregulation of Toll-like receptors in the mononuclear leukocytes of patients with active pulmonary tuberculosis. The Journal of Immunology, 176(5), 3010 - 3018.
    • Chang JS, Huggett JF, Dheda K, Kim LU, Zumla A, Rook GA (2006). Myobacterium tuberculosis induces selective up-regulation of TLRs in the mononuclear leukocytes of patients with active pulmonary tuberculosis.. J Immunol, 176(5), 3010 - 3018.
    • Davies PDO, Yew WW, Ganguly D, Davidow AL, Reichman LB, Dheda K, Rook GA (2006). Smoking and tuberculosis: the epidemiological association and immunopathogenesis. Transactions of the Royal Society of Tropical Medicine and Hygiene, 100(4), 291 - 298. doi:10.1016/j.trstmh.2005.06.034
    • Chang JS, Dheda K, Huggett JF, Kim LU, Zumla A, Rook GA (2006). Expression of IL-4 mRNA in peripheral blood mononuclear cells from normal donors in relation to expression of TLR2. Immunology Letters, 106(20), 194 - 197.
    • Rook G, Kim LU (2006). Comments on the new analysis of the Chingleput BCG trial. Indian Journal of Medical Research, 123(20), 103 - 106.

    2005

    • Rook GAW (2005). Old Friends and homoeostasis.
    • Rook GAW, Brunet LR (2005). Chronic inflammatory disorders, the gut and the 'Old Friends' hypothesis.
    • Dheda K, Udwadia ZF, Huggett JF, Johnson MA, Rook GA (2005). Utility of the antigen-specific interferon-gamma assay for the management of tuberculosis. Current Opinion in Pulmonary Medicine, 11(3), 195 - 202.
    • Rook GAW, Brunet LR (2005). Microbes, immunoregulation, and the gut.. Gut, 54(3), 317 - 320.
    • Rook GA, Martinelli R, Brunet LR (2005). Modelling gene-environment interactions in Th1- and Th2-dominated diseases of laboratory animals. Ernst Schering Research Foundation Workshop, 50, 45 - 68.
    • Dheda K, Lalvani A, Miller RF, Scott G, Booth H, Johnson MA, Zumla A, Rook GA (2005). Performance of a T-cell-based diagnostic test for tuberculosis infection in HIV-infected individuals is independent of CD4 cell count. AIDS, 9(17), 2038 - 2041.
    • Dheda K, Lampe F, Lipman MC, Johnson MA, Rook GAW (2005). HIV and leprosy in the eastern United States - Reply. J INFECT DIS, 192(9), 1674 - 1675.
    • Dheda K, Chang JS, Breen RA, Haddock JA, Huggett JF, Lipman MC, Johnson MA, Rook GAW, Zumla A (2005). Expression of a novel cytokine, IL-4delta2, in HIV and HIV-tuberculosis co-infection. AIDS, 19(15), 1601 - 1606.
    • Dheda K, Booth H, Huggett JF, Johnson MA, Zumla A, Rook GA (2005). Lung remodeling in pulmonary tuberculosis.. J Infect Dis, 192(7), 1201 - 1209. doi:10.1086/444545
    • Dheda K, Chang JS, Breen RA, Kim LU, Haddock JA, Huggett JF, Johnson MA, Rook GAW, Zumla A (2005). In vivo and in vitro studies of a novel cytokine, interleukin-4delta2, in pulmonary tuberculosis. American Journal of Respiratory and Critical Care Medicine, 172(4), 501 - 508. doi:10.1164/rccm.200502-278OC
    • Rook GAW, Dheda K, Zumla A (2005). Do successful tuberculosis vaccines need to be immunoregulatory rather thanmerely Th1-boosting?. Vaccine, 23(17-18), 2115 - 2120. doi:10.1016/j.vaccine.2005.01.069
    • Doherty TM, Demissie A, Menzies D, Anderson P, Rook G, Zumla A (2005). Effect of sample handling on analysis of cytokine responses to Mycobacterium tuberculosis in clinical samples using ELISA, ELISPOT and quantitative PCR.. Journal of Microbiological Methods, 298(1-2), 129 - 141.
    • Thapa N, Lydyard P, Rook GAW, Stanford JL (2005). The proportions of CD4, CD8, CD3 T cells in peripheral circulation of patients with pulmonary tuberculosis. SAARC Journal of Tuberculosis, Lung Diseases & HIV/AIDS, 2(1), 23 - 28.
    • Hunt JR, Martinelli R, Adams VC, Rook GA, Brunet LR (2005). Intragastric administration of Mycobacterium vaccae inhibits severe pulmonary allergic inflammation in a mouse model.. Clinical and Experimental Allergy, 35(5), 685 - 690.
    • Rook GAW, Brunet LR (2005). Old friends for breakfast. Clinical and Experimental Allergy, 35, 841 - 842.
    • Thapa N, Rook GAW, Donoghue H, Stanford JL (2005). Detection of intracellular TNF-α and IL-10 in CD4 and CD8 cells of patients with pulmonary tuberculosis using a flow cytometer. SAARC Journal of Tuberculosis, Lung Diseases & HIV/AIDS, 2(1), 10 - 14.
    • Dheda K, Huggett JF, Chang JS, Kim LU, Bustin SA, Johnson MA, Rook GAW, Zumla A (2005). The implications of using an inappropriate reference gene for real-time reverse transcription PCR data normalization. Analytical Biochemistry, 344(1), 141 - 143. doi:10.1016/j.ab.2005.05.022
    • Rook GAW, Dheda K, Zumla A (2005). Immune responses to TB in developing countries: implications for new vaccines. Nature Reviews Immunology, 5(8), 661 - 667. doi:10.1038/nri1666
    • Dheda K, Booth H, Huggett JF, Johnson MA, Zumla A, Rook GAW (2005). Lung remodelling in tuberculosis. The Journal of Infectious Diseases, 192(7), 1201 - 1210.
    • Dheda K, Chang JS, Kim LU, Huggett JF, Johnson MA, Zumla A, Rook GAW (2005). Interferon gamma assays for tuberculosis. The Lancet Infectious Diseases, 5(6), 324 - 325. doi:10.1016/S1473-3099(05)70119-5
    • Dheda K, Lampe F, Lipman MC, Johnson MA, Rook GA (2005). Reply to Lu et al. The Journal of Infectious Diseases, 192(9), 1674 - 1675.
    • Rook GAW, Martinelli R, Rosa Brunet L (2005). The "Old Friends" hypothesis: how early contact with certain microorganisms may influence regulatory circuits. In Hodgson DM, Coe CL (Ed.), Perinatal Programming: Early Life Determinants of Adult Health and Disease (pp. 183 - 194). : Taylor and Francis.
    • Hernandez-Pando R, Aguilar-Leon D, Orozco H, Serrano A, Ahlem C, Trauger R, Schramm B, Reading C, Frincke J, Rook GA (2005). 16alpha-bromoepiandrosterone restores T helper cell type 1 activity and accelerates chemotherapy-induced bacterial clearance in a model of progressive pulmonary tuberculosis. The Journal of Infectious Diseases, 191(2), 299 - 306.

    2004

    • Adams VC, Hunt JR, Martinelli R, Palmer R, Rook GA, Brunet LR (2004). Mycobacterium vaccae induces a population of pulmonary CD11c+ cells with regulatory potential in allergic mice. European Journal of Immunology, 34(3), 631 - 638.
    • Rook GA, Adams V, Hunt J, Palmer R, Martinelli R, Brunet LR (2004). Mycobacteria and other environmental organisms as immunomodulators for immunoregulatory disorders. Springer Seminars in Immunopathology, 25(3-4), 237 - 255.
    • Rook GAW (2004). The Immunology and Pathogenesis of Tuberculosis. In Madkour MM (Ed.), Tuberculosis (pp. 133 - 151). : Springer.
    • Hernandez-Pando R, Aguilar D, Hernandez ML, Orozco H, Rook G (2004). Pulmonary tuberculosis in BALB/c mice with non-functional IL-4 genes: changes in the inflammatory effects of TNF-alpha and in the regulation of fibrosis. European Journal of Immunology, 34(1), 174 - 183. doi:10.1002/eji.200324253
    • Huggett J, Dheda K, Zumla A, Rook G (2004). Crohn's disease and MAP. The Lancet, 364(9452), 2178 - 2178.
    • Onyebujoh P, Rook GAW, Roscigno G, Rustomjee R, Zumla A (2004). Tuberculosis. Nature Reviews Microbiology, 2(12), 930 - 932.
    • Dheda K, Huggett JF, Kim LU, Breen R, Haddock JA, Johnson MA, Zumla A, Rook GAW (2004). IL-4 Delta 2 and Th2 cytokines in human pulmonary tuberculosis.
    • Dheda K, Johnson MA, Zumla A, Rook GA (2004). Smoking is not beneficial for tuberculosis. American Journal of Respiratory and Critical Care Medicine, 170(7), 821 - 821.
    • Rook GA, Hernandez-Pando R, Dheda K, Teng Seah G (2004). IL-4 in tuberculosis: implications for vaccine design. Trends in Immunology, 25(9), 483 - 488.
    • Fletcher HA, Owiafe P, Jeffries D, Hill P, Rook GA, Zumla A, Doherty TM, Brookes RH Vacsel Study GROUP (2004). Increased expression of mRNA encoding interleukin (IL)-4 and its splice variant IL-4delta2 in cells from contacts of Mycobacterium tuberculosis, in the absence of in vitro stimulation.. Immunology, 112(4), 669 - 673.
    • Dheda K, Rook G, Zumla A (2004). Peripheral T Cell Interferon-{gamma} Responses and Latent Tuberculosis. American Journal of Respiratory and Critical Care Medicine, 170(1), 97 - 98.
    • Dheda K, Huggett JF, Bustin SA, Johnson MA, Rook G, Zumla A (2004). Validation of housekeeping genes for normalizing RNA expression in real-time PCR. BioTechniques, 37(1), 112, 116, - 114, 116,.
    • Dheda K, Huggett JF, Bustin SA, Johnson MA, Rook G, Zumla A (2004). Validation of housekeeping genes for normalizing RNA expression in real-time PCR.. Biotechniques, 37(1), 112 - 119.
    • Demissie A, Abebe M, Aseffa A, Rook G, Fletcher H, Zumla A, Weldingh K, Brock I, Andersen P, Doherty TM (2004). Healthy individuals that control a latent infection with Mycobacterium tuberculosis express high levels of Th 1 cytokines and the IL-4 antagonist IL-4delta2. The Journal of Immunology, 172(11), 6938 - 6943.
    • Huggett J, Dheda K, Zumla A, Rook G (2004). edicine 10:157-158. 11. Huggett J, Dheda K, Zumla A, Rook G.. The Lancet, 364, 2178 - 2179.

    2003

    • Martinelli R, Hunt JRF, Rook GAW, Rosa Brunet L (2003). Effects of Mycobacterium vaccae on peritoneal exudate cells of napve mice.
    • Camporota L, Corkhill A, Long H, Lordan J, Stanciu L, Tuckwell N, Cross A, Stanford JL, Rook GA, Holgate ST, Djukanovic R (2003). The effects of Mycobacterium vaccae on allergen-induced air responses in atopic asthma. European Respiratory Journal, 21(2), 287 - 293.
    • Walker C, Sawicka E, Rook GAW (2003). Immunotherapy with mycobacteria. Current Opinion in Allergy and Clinical Immunology, 3(6), 481 - 486.
    • Adams VC, Hunt JRF, Martinelli R, Palmer R, Rook GAW, Rosa Brunet L (2003). Mycobacterium vaccae induces a CD11c+ population that produces regulatory cytokines in the lungs of allergic mice.
    • Rook GAW, Martinelli R, Brunet LR (2003). Innate immune responses to mycobacteria and the downregulation of atopic responses. Current Opinion in Allergy and Clinical Immunology, 3(5), 337 - 342.
    • Breivik T, Rook GAW (2003). Oral treatment with SRP299 (killed Mycobacterium vaccae) inhibits experimental periodontal disease in Wistar rats. Journal of Clinical Periodontology, 30(11), 931 - 936.

    2002

    • Druilhe P, Hagan P, Rook GAW (2002). The importance of models of infection in the study of disease resistance. Trends in Microbiology, 10(10 (Su), S38 - S46.
    • Rook GAW (2002). Immunoregulation: the hygiene hypothesis and the brain.
    • Rook GAW, Rosa Brunet L, Hunt J (2002). Multiple consequences of the changing educational input to our immune systems. In Heidt PJ, Midtvedt T, Rusch V, van der Waaij D (Ed.), Probiotics: Bacteria and Bacterial Fragments as Immunomodulatory Agents (pp. 35 - 53). : Institut f+r Integrative Biologie GmbH.
    • Rosa Brunet L, Hunt J, Rook GAW (2002). Dangers of therapeutic manipulation of the Th1--Th2 balance. Trends in Immunology, 23(3), 127 - 128.
    • Zuany-Amorim C, Sawicka E, Manlius C, Le Moine A, Rosa Brunet L, Kemeny DM, Bowen G, Rook G, Walker C (2002). Suppression of airway eosinophilia by killed Mycobacterium vaccae- induced allergen-specific regulatory T-cells. Nature Medicine, 8(6), 625 - 629.
    • Brelvik T, Rook GA (2002). Treatment with SRL172 (heat-killed Mycobacterium vaccae) inhibits progression of established experimental periodontal disease in Wistar rats. Journal of Periodontal Research, 37(3), 210 - 214.
    • Zuany-Amorim C, Manlius C, Trifilieff A, Rosa Brunet L, Rook G, Bowen G, Pay G, Walker C (2002). Long-term protective and antigen-specific effect of heat-killed Mycobacterium vaccae in a murine model of allergic pulmonary inflammation. The Journal of Immunology, 169(3), 1492 - 1499.
    • Rook GAW, Rosa Brunet L (2002). Give us this day our daily germs. Biologist, 49(4), 145 - 149.
    • Rook GA, Lightman SL, Heijnen CJ (2002). Can nerve damage disrupt neuroendocrine immune homeostasis? Leprosy as a case in point.. Trends Immunol, 23(1), 18 - 22.
    • Stansby G, Chan YC, Berwanger CS, Shurey S, Rook GA, Stanford JL (2002). Prevention of experimental myointimal hyperplasia by immunomodulation. European Journal of Vascular and Endovascular Surgery, 23(1), 23 - 28.
    • Rook GA, Lightman SL, Heijnen CJ (2002). Can nerve damage disrupt neuroendocrine immune homeostasis? Leprosy as a case in point. Trends in Immunology, 23(1), 18 - 22.
    • Adams VC, Hunt JR, Rosa Brunet L, Rook GAW (2002). Effect of Mycobacterium vaccae on ICOS expression in a murine model.
    • Arriaga AK, Orozco EH, Aguilar LD, Rook GA, Hernandez PR (2002). Immunological and pathological comparative analysis between experimental latent tuberculous infection and progressive pulmonary tuberculosis. Clinical and Experimental Immunology, 128(2), 229 - 237.

    2001

    • Rook GA, Rosa-Brunet L, Hunt J (2001). Cat allergen and sensitisation. The Lancet, 357(9274), 2137 - 2138.
    • Everest P, Wain J, Roberts M, Rook G, Dougan G (2001). The molecular mechanisms of severe typhoid fever. TRENDS MICROBIOL, 9(7), 316 - 320.
    • Seah GT, Rook GA (2001). Il-4 influences apoptosis of mycobacterium-reactive lymphocytes in the presence of TNF-alpha. The Journal of Immunology, 167(3), 1230 - 1237.
    • Rook G (2001). Th1-or Th2-cell commitment during infectious disease: an oversimplification?. TRENDS IMMUNOL, 22(9), 481 - 481.
    • Rook GA, Zumla A (2001). Advances in the immunopathogenesis of pulmonary tuberculosis. Current Opinion in Pulmonary Medicine, 7(3), 116 - 123.
    • Rook GAW (2001). The role of mycobacteria in the education of the developing immune system. CLIN EXP ALLERGY, 31(1), 165 - 165.
    • Seah GT, Rook GA (2001). High levels of mRNA encoding IL-4 in unstimulated peripheral blood mononuclear cells from tuberculosis patients revealed by quantitative nested reverse transcriptase-polymerase chain reaction; correlations with serum IgE levels. Scandinavian Journal of Infectious Diseases, 33(2), 106 - 109.
    • Rook GA, Seah G, Ustianowski A (2001). M. tuberculosis: immunology and vaccination. European Respiratory Journal, 17(3), 537 - 557.
    • Rook GA (2001). The TGF-beta1 paradox in asthma. Trends in Immunology, 22(6), 299 - 300.
    • Seah GT, Gao PS, Hopkin JM, Rook GA (2001). Interleukin-4 and its alternatively spliced variant (IL-4delta2) in patients with atopic asthma. American Journal of Respiratory and Critical Care Medicine, 164(6), 1016 - 1018.

    2000

    • Rook GA (2000). Clean Living increases more than just atopic disease. Immunology Today, 21(5), 249 - 250.
    • Baker RW, Walker BR, Shaw RJ, Honour JW, Jessop DS, Lightman SL, Zumla A, Rook GA (2000). Increased cortisol: cortisone ratio in acute pulmonary tuberculosis.. Am J Respir Crit Care Med, 162(5), 1641 - 1647. doi:10.1164/ajrccm.162.5.9912119
    • Baker RW, Walker BR, Shaw RJ, Honour JW, Jessop DS, Lightman SL, Zumla A, Rook GA (2000). Increased cortisol: cortisone ratio in acute pulmonary tuberculosis. American Journal of Respiratory and Critical Care Medicine, 162(5), 1641 - 1647.
    • Rook GA, Ristori G, Salvetti M, Giovannoni G, Thompson EJ, Stanford JL (2000). Bacterial vaccines for the treatment of multiple sclerosis and other autoimmune disorders. Immunology Today, 21(10), 503 - 508.
    • Hernandez-Pando R, Orozco EH, Arriaga K, Pavon L, Rook GA (2000). Treatment with BB-94, a broad spectrum inhibitor of zinc-dependent metalloproteinases, causes deviation of the cytokine profile towards type-2 in experimental pulmonary tuberculosis in Balb/c mice. International Journal of Experimental Pathology, 81(3), 199 - 209.
    • Seah GT, Scott GM, Rook GA (2000). Type 2 cytokine gene activation and its relationship to the extent of disease in patients with tuberculosis. The Journal of Infectious Diseases, 181(1), 385 - 389.
    • Hernandez-Pando R, Jeyanathan M, Mengistu G, Aguilar D, Orozco H, Harboe M, Rook GA, Bjune G (2000). Persistence of DNA from Mycobacterium tuberculosis in superficially normal lung tissue during latent infection. The Lancet, 356(9248), 2133 - 2138.
    • Hernandez-Pando R, Pavon L, Orozco EH, Rangel J, Rook GA (2000). Interactions between hormone-mediated and vaccine-mediated immunotherapy for pulmonary tuberculosis in BALB/c mice. Immunology, 100(3), 391 - 398.
    • Breivik T, Rook GA (2000). Prevaccination with SRL172 (heat-killed Mycobacterium vaccae) inhibits experimental periodontal disease in Wistar rats. Clinical and Experimental Immunology, 120(3), 463 - 467.
    • Amiel C, Kusnierz JP, Mouton Y, Rook GA, Stanford JL, Singh M, Capron A, Bahr GM (2000). Cytokine analysis and the single cell level and lymphoproliferative responses to mycobacterial antigens in HIV-1 patients with successful virologic response to potent antiretrovirals. Journal of Clinical Immunology, 20(6), 458 - 465.
    • Rook G, Baker R, Walker B, Honour J, Jessop D, Hernandez-Pando R, Arriaga K, Shaw R, Zumla A, Lightman S (2000). Local regulation of glucocorticoid activity in sites of inflammation. Insights from the study of tuberculosis. Annals of the New York Academy of Sciences, 917, 913 - 922.

    1999

    • Rook GA (1999). Glucocorticoids and immune function.. Baillieres Best Pract Res Clin Endocrinol Metab, 13(4), 567 - 581.
    • Rook GAW, Stanford JL (1999). Skin-test responses to mycobacteria in atopy and asthma. ALLERGY, 54(3), 285 - 286.
    • Leirisalo-Repo M, Hernandez-Munoz HE, Rook GAW (1999). Agalactosyl IgG is elevated in patients with active spondyloarthropathy. RHEUMATOL INT, 18(5-6), 171 - 176.
    • Rook GA, Baker R (1999). Cortisol metabolism, cortisol sensitivity and the pathogenesis of leprosy reactions.. Trop Med Int Health, 4(7), 493 - 498.
    • Maraveyas A, Baban B, Kennard D, Rook GAW, Westby M, Grange JM, Lydyard P, Stanford JL, Jones M, Selby P, Dalgleish AGD (1999). Possible improved survival of patients with stage IV AJCC melanoma receiving SRL 172 immunotherapy: Correlation with induction of increased levels of intracellular interleukin-2 in peripheral blood lymphocytes. ANN ONCOL, 10(7), 817 - 824.
    • Onyebujoh PC, Levin JB, Fourie FB, Garhiram V, Tembe LC, Phili NP, Mthiyane TCP, Moniwa T, Bayer G, Ramajoe IM, Mncwabe TAB, Mallisar LGM, Saul TNM, Levin JB, Jackson THFG, Suparsad S, Fine PEM, Pendlebury DJS, Fine E, Houghton I, Clyde J, Vos HP, Padayatchi N, Pala A, Ramjee A, Ramjee M, Ramdeen J, Masters IH, Osbourne G, Naidu K, Bamba S, Mazur B, Czarnocki R, Landers K, Ndlovu G, Maphumulo N, Garhiram V, Sturm AW, Moodley J, Pillay C, Roux L, Moodley R, Sarawan A, Jali T, Manickam F, Smith A, Gopaul , Durosanmi T, Moonsammy R, Wyld P, McCallum J, Fulton C, Bisset K, Henderson S, Stewart D, Nticinka O, Watson D, Tuckwell N, Kennard D, Stanford JL, Rook GA, Grange JM, Zumla AA, Bateman E, Hopwell P, Darbyshire J, Geiter L, Nunn A, Weyer K, Durban Immunotherapy Trial Grp (1999). Immunotherapy with Mycobacterium vaccae in patients with newly diagnosed pulmonary tuberculosis: a randomised controlled trial. LANCET, 354(9173), 116 - 119.
    • Seah GT, Rook GAW (1999). A sensitive, non-radioactive quantitative method for measuring IL-4 and IL-4 delta 2 mRNA in unstimulated cells from multiple clinical samples, using nested RT-PCR. J IMMUNOL METHODS, 228(1-2), 139 - 149.

    1998

    • Rook GA, Zumla A (1998). Is the Gulf War syndrome an immunologically mediated phenomenon? [editorial]. Hospital Medicine, 59(1), 10 - 11.
    • Rook GA, Zumla A (1998). Is the Gulf War syndrome an immunologically mediated phenomenon?. Hosp Med, 59(1), 10 - 11.
    • Russell D, Rook GAW, Blackwell JM, Kaplan G, Wadee AA, Orme I, Ehlers MRW, Brennan PJ, Ulmer JB, Ress S, Kramnik I (1998). Endocytic trafficking and the mycobacterial vacuole - General discussion I.
    • Rook GA, Hernandez-Pando R (1998). Immunological and endocrinological characteristics of tuberculosis that provide opportunities for immunotherapeutic intervention.. Novartis Found Symp, 217, 73 - 87.
    • Kon OM, Goyal M, Filley E, Gleissberg G, Cunningham D, Rook GAW, Shaw RJ (1998). Mycobacterium vaccae: a study of safety and outcome measures. RESP MED, 92(3), 597 - 598.
    • Wang CC, Rook GA (1998). Inhibition of an established allergic response to ovalbumin in BALB/c mice by killed Mycobacterium vaccae.. Immunology, 93(3), 307 - 313.
    • Rook GA, Stanford JL (1998). Give us this day our daily germs.. Immunol Today, 19(3), 113 - 116.
    • Trao VT, Huong PLT, Thuan AT, Anh DD, Trach DD, Rook GAW, Wright EP (1998). Changes in cellular response to mycobacterial antigens and cytokine production patterns in leprosy patients during multiple drug therapy. IMMUNOLOGY, 94(2), 197 - 206.
    • Leirisalo-Repo M, Hernandez-Munoz H, Paimela L, Rook GAW (1998). Agalactosyl IGG is a prognostic marker in early rheumatoid arthritis.. ARTHRITIS RHEUM, 41(9), S272 - S272.
    • Hernandez-Pando R, Streber MDL, Orozco H, Arriaga K, Pavon L, Al-Nakhli SA, Rook GAW (1998). The effects of androstenediol and dehydroepiandrosterone on the course and cytokine profile of tuberculosis in BALB/c mice. IMMUNOLOGY, 95(2), 234 - 241.
    • Converse PJ, Dannenberg AM, Shigenaga T, McMurray DN, Phalen SW, Stanford JL, Rook GAW, Koru-Sengul T, Abbey H, Estep JE, Pitt MLM (1998). Pulmonary bovine-type tuberculosis in rabbits: Bacillary virulence, inhaled dose effects, tuberculin sensitivity, and Mycobacterium vaccae immunotherapy. CLIN DIAGN LAB IMMUN, 5(6), 871 - 881.
    • Hernandez-Pando R, de la Luz Streber M, Orozco H, Arriaga K, Pavon L, Marti O, Lightman SL, Rook GA (1998). Emergent immunoregulatory properties of combined glucocorticoid and anti-glucocorticoid steroids in a model of tuberculosis.. QJM, 91(11), 755 - 766.

    1997

    • Baker R, Shaw RJ, Rook GAW, Honour J, Lightman SL, Walker BR, Zumla A (1997). Glucocorticoids and Acute Pulmonary Tuberculosis: a clue to pathogenesis?.
    • Baker R, Shaw RJ, Rook GAW, Honour J, Lightman SL, Walker BR, Zumla A (1997). Patients with acute pulmonary tuberculosis (Tb) have subtle abnormalities of glucocorticoid metabolism which may affect immune responses.
    • Rook GA, Zumla A (1997). Gulf War syndrome: is it due to a systemic shift in cytokine balance towards a Th2 profile?. The Lancet, 349(9068), 1831 - 1833.
    • Baker R, Rook GA, Zumla A (1997). Adrenal function and the hypothalamo-pituitary adrenal axis in immunodeficiency virus-associated tuberculosis. International Journal of Tuberculosis and Lung Disease, 1(3), 289 - 291.
    • Gaora PO, Barnini S, Hayward C, Filley E, Rook G, Young D, Thole J (1997). Mycobacteria as immunogens: Development of expression vectors for use in multiple mycobacterial species. MED PRIN PRACT, 6(2), 91 - 96.
    • Rook GAW, Hernandez-Pando R, Baker R, Orozco H, Arriaga K, Pavol L, Streber M (1997). Human and murine tuberculosis as models for immuno-endocrine interactions. In Rook GAW, Lightman S (Ed.), Steroid hormones and the T cell cytokine profile (pp. 193 - 220). : Springer.
    • Hernandez-Pando R, Pavon L, Arriaga K, Orozco H, Madrid-Marina V, Rook GAW (1997). Pathogenesis of tuberculosis in mice exposed tolow and high doses of an environmental mycobacterial saprophyte. INFECT IMMUN, (65), 3310 - 3316.
    • Rook GAW, Hernandez-Pando R (1997). The influence of adrenal steroids on macrophage and T-cell function in tuberculosis. In Bendinelli M, Paradise LJ, Friedman H (Ed.), Opportunistic Intracellular Pathogens and Immunity (pp. - ). : Plenum Publishing Corp.
    • Rook GAW, HernandezPando R, Stanford JL (1997). Protection and immunopathology in tuberculosis: The role of immunotherapy. J PHARM PHARMACOL, 49, 47 - 51.
    • Rook GAW, Hernandez-Pando R (1997). Pathogenetic role in human and murine tuberculosis of changes in the peripheral metabolism of glucocorticoids and antiglucocorticoids. Psychoneuroendocrinology, 22, S109 - S113.
    • HernandezPando R, Pavon L, Arriaga K, Orozco H, MadridMarina V, Rook G (1997). Pathogenesis of tuberculosis in mice exposed to low and high doses of an environmental mycobacterial saprophyte before infection. INFECT IMMUN, 65(8), 3317 - 3327.
    • Rook GAW, HernandezPando R, Baker R (1997). The potential of the endocrine system for tuberculosis therapy. J PHARM PHARMACOL, 49, 43 - 46.
    • Rook GAW, Hernandez-Pando R, Baker R (1997). The potential of the endocrine system for tuberculosis therapy. J PHARM PHARMACOL, 49(1), 43 - 46.
    • Baker R, Shaw RJ, Rook GAW, Honour J, Lightman SL, Walker BR, Zumla A (1997). Are there subtle abnormalities of glucocorticoid metabolism in active pulmonary tuberculosis which affect immune responses?.
    • Fakoya A, Matear PM, Filley E, Rook GAW, Stanford J, Gilson RJC, Beecham N, Weller IVD, Vyakarnam A (1997). HIV infection alters the production of both type 1 and type 2 cytokines but does not induce a polarised type 1 or type 2 state. AIDS, 11(12), 1445 - 1452. doi:10.1097/00002030-199712000-00008
    • Khosravi AD, Stanford JL, Donoghue HD, Rook GA (1997). Variation within Mycobacterium scrofulaceum. Journal of Applied Microbiology, 83(5), 596 - 602.
    • Stanford JL, Rook GAW (1997). Potential immunotherapy for tuberculosis and future potential for HIV. In Zumla A, Johnson M, Miller R (Ed.), AIDS and respiratory medicine (pp. 375 - 393). : Chapman & Hall Medical.
    • Rook GAW, Baker R, Zumla A (1997). Steroid metabolism and immunity: therapeutic implications. BioDrugs, 8(3), 157 - 163.
    • Rook GAW (1997). Intractable mycobacterial infections associated with genetic defects in the receptor for interferon gamma: what does this tell us about immunity to mycobacteria?. Thorax, 52, S41 - S46.
    • Hernandez-Pando R, Pavon L, Arriaga K, Orozco H, Madrid-Marina V, Rook GAW (1997). Improvement and exacerbation of murine tuberculosis by previous exposure to low and high doses of an environmental mycobacterial saprophyte. Infection and Immunity, 65, 3310 - 3316.
    • Baker R, Rook GAW, Zumla A (1997). Adrenal function and the hypothalamo-pituitary adrenal axis in immunodeficiency virus-associated tuberculosis. International Journal of Tuberculosis and Lung Disease, 1(3), 289 - 291.
    • Rook GAW, Hernandez-Pando R, Stanford JL (1997). Immunotherapy of intracellular infections. In Van der Meer JWM, Michel MF, Verbrugh HA (Ed.), New Approaches to Intracellular Bacterial Infections (pp. 95 - 106). : SmithKline Beecham Farma b.v..
    • Baker R, Shaw RJ, Rook GAW, Honour J, Lightman SL, Walker BR, Zumla A (1997). Patients with acute pulmonary tuberculosis (Tb) have subtle but crucial abnormalities of steroid metabolism which may persist after cure or be constitutive.
    • Rook GA, Baker R, Zumla A (1997). Steroid metabolism and immunity: therapeutic implications. Biodrugs, 8, 3 - 3.

    1996

    • Donald PR, Beyers N, Rook GAW (1996). Adolescent tuberculosis. S AFR MED J, 86(3), 231 - 233.
    • Rook GAW, HernandezPando R (1996). Cellular immune responses in tuberculosis: Protection and immunopathology.
    • Baker RW, Zumla A, Rook GAW (1996). Tuberculosis, steroid metabolism and immunity. QJM-INT J MED, 89(5), 387 - 394.
    • Pilkington C, Basaran M, Barlan I, Costello AM, Rook GA (1996). Raised levels of agalactosyl IgG in childhood tuberculosis.. Trans R Soc Trop Med Hyg, 90(2), 167 - 168.
    • Pilkington C, Taylor PV, Silverman E, Isenberg DA, Costello AM, Rook GA (1996). Agalactosyl IgG and materno-fetal transmission of autoimmune neonatal lupus.. Rheumatol Int, 16(3), 89 - 94.
    • Rook GA, Stanford JL (1996). The Koch phenomenon and the immunopathology of tuberculosis.. Curr Top Microbiol Immunol, 215, 239 - 262.
    • Rook GA, Hernandez-Pando R (1996). The pathogenesis of tuberculosis.. Annu Rev Microbiol, 50, 259 - 284. doi:10.1146/annurev.micro.50.1.259
    • Groenink J, Spijker J, vandenHerikOudijk IE, Boeije L, Rook G, Aarden L, Smeenk R, vandeWinkel JGJ, vandenBroek MF (1996). On the interaction between agalactosyl IgG and Fc gamma receptors. EUR J IMMUNOL, 26(6), 1404 - 1407.
    • Rook GAW, Honour J, Kon OM, Wilkinson RJ, Davidson R, Shaw RJ (1996). Urinary adrenal steroid metabolites in tuberculosis - A new clue to pathogenesis?. QJM-INT J MED, 89(5), 333 - 341.

    1995

    • GRANGE JM, STANFORD JL, ROOK GAW (1995). TUBERCULOSIS AND CANCER - PARALLELS IN HOST RESPONSES AND THERAPEUTIC APPROACHES. LANCET, 345(8961), 1350 - 1352.
    • FAKOYA A, MATEAR PM, FILLEY E, ROOK GAW, STANFORD J, GILSON RJC, MAINI M, WELLER IVD, VYAKARNAM A (1995). TH1/TH2 OR TH0-QUESTIONABLE CYTOKINE PATTERNS IN HEALTHY HIV-INFECTED INDIVIDUALS.
    • HERNANDEZPANDO R, OROZCO H, HONOUR J, SILVA P, LEYVA R, ROOK GAW (1995). ADRENAL CHANGES IN MURINE PULMONARY TUBERCULOSIS - A CLUE TO PATHOGENESIS. FEMS IMMUNOL MED MIC, 12(1), 63 - 72.
    • Polla BS, Baladi S, Fuller K, Rook G (1995). Presence of hsp65 in bacterial extracts (OM-89): a possible mediator of orally-induced tolerance?. Experientia, 51(8), 775 - 779.
    • GRANGE JM, STANFORD JL, ROOK GAW, WRIGHT P (1995). ROLE OF VIRAL-INFECTIONS IN THE INCEPTION OF CHILDHOOD ASTHMA AND ALLERGIES. THORAX, 50(6), 701 - 701.
    • Onyebujoh PC, Abdulmumini T, Robinson S, Rook GA, Stanford JL (1995). Immunotherapy with Mycobacterium vaccae as an addition to chemotherapy for the treatment of pulmonary tuberculosis under difficult conditions in Africa.. Respir Med, 89(3), 199 - 207.
    • Kumpel BM, Wang Y, Griffiths HL, Hadley AG, Rook GA (1995). The biological activity of human monoclonal IgG anti-D is reduced by beta-galactosidase treatment.. Hum Antibodies Hybridomas, 6(3), 82 - 88.
    • Rook GA, Stanford JL (1995). Adjuvants, endocrines and conserved epitopes; factors to consider when designing "therapeutic vaccines".. Int J Immunopharmacol, 17(2), 91 - 102.
    • Costello AM, Rook G (1995). Tuberculosis in children.. Curr Opin Pediatr, 7(1), 6 - 12.
    • McCulloch J, Zhang YW, Dawson M, Harkiss GD, Peterhans E, Vogt HR, Lydyard PM, Rook GA (1995). Glycosylation of IgG during potentially arthritogenic lentiviral infections.. Rheumatol Int, 14(6), 243 - 248.
    • Pilkington C, Lefvert AK, Rook GA (1995). Neonatal myasthenia gravis and the role of agalactosyl IgG.. Autoimmunity, 21(2), 131 - 135.
    • Pilkington C, Yeung E, Isenberg D, Lefvert AK, Rook GA (1995). Agalactosyl IgG and antibody specificity in rheumatoid arthritis, tuberculosis, systemic lupus erythematosus and myasthenia gravis.. Autoimmunity, 22(2), 107 - 111.
    • ONYEBUJOH PC, ABDULMUMINI T, ROBINSON S, ROOK GAW, STANFORD JL (1995). IMMUNOTHERAPY WITH MYCOBACTERIUM-VACCAE AS AN ADDITION TO CHEMOTHERAPY FOR THE TREATMENT OF PULMONARY TUBERCULOSIS UNDER DIFFICULT CONDITIONS IN AFRICA. RESP MED, 89(3), 199 - 207.

    1994

    • STANFORD JL, STANFORD CA, ROOK GAW, GRANGE JM (1994). IMMUNOTHERAPY FOR TUBERCULOSIS - INVESTIGATIVE AND PRACTICAL ASPECTS. CLIN IMMUNOTHER, 1(6), 430 - 440.
    • STANFORD JL, ROOK GAW, HOLTON J, JENKINS PA, GRANGE JM (1994). INFLAMMATORY BOWEL-DISEASE. LANCET, 343(8909), 1359 - 1360.
    • Fidler HM, Thurrell W, Johnson NM, Rook GA, McFadden JJ (1994). Specific detection of Mycobacterium paratuberculosis DNA associated with granulomatous tissue in Crohn's disease.. Gut, 35(4), 506 - 510.
    • EDELSTEN C, GRAHAM E, CHANG Y, ROOK G, STANFORD J (1994). CHANGES IN IMMUNOGLOBULIN GLYCOSYLATION ACCOMPANY ACTIVE DISEASE IN IDIOPATHIC UVEORETINITIS. INVEST OPHTH VIS SCI, 35(4), 2093 - 2093.
    • PILKINGTON C, ROOK G, ISENBERG DA (1994). GLYCOSYLATION OF IMMUNOGLOBULINS - PROSPECTS FOR DIAGNOSIS AND THERAPY IN RHEUMATOLOGY. CLIN IMMUNOTHER, 1(3), 169 - 172.
    • Bodman KB, Hutchings PR, Jeddi PA, Delves PJ, Rook GAW, Sumar N, Roitt IM, Lydyard PM (1994). IgG glycosylation in autoimmune-prone strains of mice.. Clinical and Experimental Immunology, 95, 103 - 107.
    • Filley E, Thole JE, Rook GA, Nagai S, Waters M, Drijfhout JW, Rinke de Wit TF, De Vries RR, Abou-Zeid C (1994). Identification of an antigenic domain on Mycobacterium leprae protein antigen 85B, which is specifically recognized by antibodies from patients with leprosy.. J Infect Dis, 169(1), 162 - 169.
    • Rook GA, Onyebujoh P, Wilkins E, Ly HM, al Attiyah R, Bahr G, Corrah T, Hernandez H, Stanford JL (1994). A longitudinal study of per cent agalactosyl IgG in tuberculosis patients receiving chemotherapy, with or without immunotherapy.. Immunology, 81(1), 149 - 154.
    • Rook GA (1994). Macrophages and Mycobacterium tuberculosis: the key to pathogenesis.. Immunol Ser, 60, 249 - 261.
    • Kumpel BM, Rademacher TW, Rook GA, Williams PJ, Wilson IB (1994). Galactosylation of human IgG monoclonal anti-D produced by EBV-transformed B-lymphoblastoid cell lines is dependent on culture method and affects Fc receptor-mediated functional activity.. Hum Antibodies Hybridomas, 5(3-4), 143 - 151.
    • van Zeben D, Rook GA, Hazes JM, Zwinderman AH, Zhang Y, Ghelani S, Rademacher TW, Breedveld FC (1994). Early agalactosylation of IgG is associated with a more progressive disease course in patients with rheumatoid arthritis: results of a follow-up study.. Br J Rheumatol, 33(1), 36 - 43.
    • Tun RY, Smith MD, Lo SS, Rook GA, Lydyard P, Leslie RD (1994). Antibodies to heat shock protein 65 kD in type 1 diabetes mellitus.. Diabet Med, 11(1), 66 - 70.
    • BOTTASSO OA, INGLEDEW N, KENI M, MORINI J, PIVIDORI JF, ROOK GAW, STANFORD JL (1994). CELLULAR IMMUNE-RESPONSE TO COMMON MYCOBACTERIAL ANTIGENS IN SUBJECTS SEROPOSITIVE FOR TRYPANOSOMA-CRUZI. LANCET, 344(8936), 1540 - 1541.
    • Rook GA, Hernandez-Pando R (1994). T cell helper types and endocrines in the regulation of tissue-damaging mechanisms in tuberculosis.. Immunobiology, 191(4-5), 478 - 492. doi:10.1016/S0171-2985(11)80454-7
    • Smith MD, Lamour A, Boylston A, Lancaster FC, Pennec YL, van Agthoven A, Rook GA, Roncin S, Lydyard PM, Youinou PY (1994). Selective expression of V beta families by T cells in the blood and salivary gland infiltrate of patients with primary Sjögren's syndrome.. J Rheumatol, 21(10), 1832 - 1837.
    • Hernández-Pando R, Reyes P, Espitia C, Wang Y, Rook G, Mancilla R (1994). Raised agalactosyl IgG and antimycobacterial humoral immunity in Takayasu's arteritis.. J Rheumatol, 21(10), 1870 - 1876.
    • ROOK GAW, ONYEBUJOH P, STANFORD JL (1994). IMMUNOENDOCRINOLOGICAL HYPOTHESIS OF HIV-INFECTION. LANCET, 344(8923), 681 - 681.
    • HERNANDEZPANDO R, ROOK GAW (1994). THE ROLE OF TNF-ALPHA IN T-CELL-MEDIATED INFLAMMATION DEPENDS ON THE TH1/TH2 CYTOKINE BALANCE. IMMUNOLOGY, 82(4), 591 - 595.
    • Rook GA, Hernandez-Pando R, Lightman SL (1994). Hormones, peripherally activated prohormones and regulation of the Th1/Th2 balance.. Immunol Today, 15(7), 301 - 303. doi:10.1016/0167-5699(94)90075-2
    • GRANGE JM, STANFORD JL, ROOK G, ONYEBUJOH P, BRETSCHER PA (1994). TUBERCULOSIS AND HIV - LIGHT AFTER DARKNESS. THORAX, 49(6), 537 - 539.

    1993

    • Pilkington C, Costello AM, Rook GA, Stanford JL (1993). Development of IgG responses to mycobacterial antigens.. Arch Dis Child, 69(6), 644 - 649.
    • ROOK GAW, PILKINGTON C, TAYLOR P, LEFVERT AK (1993). CIRCUMSTANTIAL EVIDENCE THAT AGALACTOSYL IGG HAS A PATHOGENETIC ROLE IN AUTOANTIBODY-MEDIATED DISEASE. J CELL BIOCHEM, , 151 - 151.
    • ROOK GAW, ONYEBUJOH P, STANFORD JL (1993). TH1/TH2 SWITCHING AND LOSS OF CD4+ T-CELLS IN CHRONIC INFECTIONS - AN IMMUNOENDOCRINOLOGICAL HYPOTHESIS NOT EXCLUSIVE TO HIV. IMMUNOL TODAY, 14(11), 568 - 569.
    • STANFORD JL, ONYEBUJOH PC, ROOK GAW, GRANGE JM, POZNIAK A (1993). OLD PLAGUE, NEW PLAGUE, AND A TREATMENT FOR BOTH. AIDS, 7(9), 1275 - 1277.
    • LYDYARD PM, SMITH MD, LAMOUR A, BOYLSTON A, LANCASTER FC, PONNEC YL, VANAGTHOVEN A, ROOK GA, YOUINOU PY (1993). SELECTIVE EXPRESSION OF V-BETA FAMILIES BY T-CELLS IN PRIMARY SJOGRENS-SYNDROME. ARTHRITIS RHEUM, 36(9), S197 - S197.
    • STANFORD JL, STANFORD CA, ROOK GAW, CARSWELL JW, GRANGE JM, POZNIAK A (1993). CHEMOPROPHYLAXIS FOR TUBERCULOSIS. RESP MED, 87(5), 398 - 399.
    • Lambert C, Brealey R, Steele J, Rook GA (1993). The interaction of Tamm-Horsfall protein with the extracellular matrix.. Immunology, 79(2), 203 - 210.
    • FIDLER H, ROOK G, JOHNSON NM, MCFADDEN JJ (1993). MYCOBACTERIA AND SARCOIDOSIS - REPLY. BRIT MED J, 306(6887), 1270 - 1271.
    • McCulloch J, Lydyard PM, Rook GA (1993). Rheumatoid arthritis: how well do the theories fit the evidence?. Clin Exp Immunol, 92(1), 1 - 6.
    • Rook GA, Lydyard PM, Stanford JL (1993). A reappraisal of the evidence that rheumatoid arthritis and several other idiopathic diseases are slow bacterial infections.. Ann Rheum Dis, 52 Suppl 1, S30 - S38.
    • Fidler H, Rook GA, Johnson NM, McFadden JJ (1993). Search for mycobacterial DNA in granulomatous tissues from patients with sarcoidosis using the polymerase chain reaction.. Am Rev Respir Dis, 147(3), 777 - 778. doi:10.1164/ajrccm/147.3.777a
    • FIDLER HM, ROOK GA, JOHNSON NM, MCFADDEN J (1993). MYCOBACTERIUM-TUBERCULOSIS DNA IN TISSUE AFFECTED BY SARCOIDOSIS. BRIT MED J, 306(6877), 546 - 549.
    • FIDLER H, ROOK G, JOHNSON NM, OCONNOR C (1993). ETIOLOGY OF TUBERCULIDS. LANCET, 341(8844), 565 - 566.
    • ROOK GAW (1993). NEW MEANINGS FOR AN OLD WORD - ADJUVANTICITY, CYTOKINES AND T-CELLS. IMMUNOL TODAY, 14(2), 95 - 96.
    • FIDLER H, ROOK GAW, JOHNSON NM, MCFADDEN JJ (1993). SPECIFICITY OF PRIMERS BASED ON IS6110 TO MYCOBACTERIUM-TUBERCULOSIS COMPLEX DNA. TUBERCLE LUNG DIS, 74(6), 414 - 415.

    1992

    • GOUGEON ML, MONTAGNIER L, COLLINS FM, COKER RJ, WEBER JN, BROWN IN, HELLYER TJ, ROOK GAW, VYAKARNAM A, YAJKO DM, RASTOGI N, MCFADDEN JJ (1992). MYCOBACTERIA AND AIDS - EPIDEMIOLOGIC AND GENETIC-MARKERS, VIRULENCE FACTORS AND INTERACTIONS WITH THE IMMUNE-SYSTEM - DISCUSSION. RES MICROBIOL, 143(4), 430 - 436.
    • Rook GA, Stanford JL (1992). Slow bacterial infections or autoimmunity?. Immunol Today, 13(5), 160 - 164. doi:10.1016/0167-5699(92)90119-R
    • Mattsson R, Mattsson A, Hansson I, Holmdahl R, Rook GA, Whyte A (1992). Increased levels of prolactin during, but not after, the immunisation with rat collagen II enhances the course of arthritis in DBA/1 mice.. Autoimmunity, 11(3), 163 - 170.
    • Hitsumoto Y, Thompson SJ, Zhang YW, Rook GA, Elson CJ (1992). Relationship between interleukin 6, agalactosyl IgG and pristane-induced arthritis.. Autoimmunity, 11(4), 247 - 254.
    • OCONNOR CM, ROOK G, FITZGERALD MX (1992). SERUM AGALACTOSYL IGG LEVELS IN SARCOIDOSIS.
    • Sharif M, Worrall JG, Singh B, Gupta RS, Lydyard PM, Lambert C, McCulloch J, Rook GA (1992). The development of monoclonal antibodies to the human mitochondrial 60-kd heat-shock protein, and their use in studying the expression of the protein in rheumatoid arthritis.. Arthritis Rheum, 35(12), 1427 - 1433.
    • Filley EA, Bull HA, Dowd PM, Rook GA (1992). The effect of Mycobacterium tuberculosis on the susceptibility of human cells to the stimulatory and toxic effects of tumour necrosis factor.. Immunology, 77(4), 505 - 509.
    • Rook G, McCulloch J (1992). HLA-DR4, mycobacteria, heat-shock proteins, and rheumatoid arthritis.. Arthritis Rheum, 35(12), 1409 - 1412.
    • Costello AM, Kumar A, Narayan V, Akbar MS, Ahmed S, Abou-Zeid C, Rook GA, Stanford J, Moreno C (1992). Does antibody to mycobacterial antigens, including lipoarabinomannan, limit dissemination in childhood tuberculosis?. Trans R Soc Trop Med Hyg, 86(6), 686 - 692.
    • Thompson SJ, Hitsumoto Y, Zhang YW, Rook GA, Elson CJ (1992). Agalactosyl IgG in pristane-induced arthritis. Pregnancy affects the incidence and severity of arthritis and the glycosylation status of IgG.. Clin Exp Immunol, 89(3), 434 - 438.
    • al Attiyah R, Moreno C, Rook GA (1992). TNF alpha-mediated tissue damage in mouse footpads primed with mycobacterial preparations.. Res Immunol, 143(6), 601 - 610.
    • Rook G (1992). Tumours and Coley's toxins.. Nature, 357(6379), 545 - . doi:10.1038/357545a0
    • al Attiyah R, Rosen H, Rook GA (1992). A model for the investigation of factors influencing haemorrhagic necrosis mediated by tumour necrosis factor in tissue sites primed with mycobacterial antigen preparations.. Clin Exp Immunol, 88(3), 537 - 542.
    • Rook GA, Vyakarnam A (1992). Cytokines, lymphokines, mycobacteria and AIDS.. Res Microbiol, 143(4), 406 - 410.
    • Foley NM, Millar AB, Meager A, Johnson NM, Rook GA (1992). Tumour necrosis factor production by alveolar macrophages in pulmonary sarcoidosis and tuberculosis.. Sarcoidosis, 9(1), 29 - 34.

    1991

    • Rook GA, Steele J, Brealey R, Whyte A, Isenberg D, Sumar N, Nelson JL, Bodman KB, Young A, Roitt IM (1991). Changes in IgG glycoform levels are associated with remission of arthritis during pregnancy.. J Autoimmun, 4(5), 779 - 794.
    • Abou-Zeid C, Garbe T, Lathigra R, Wiker HG, Harboe M, Rook GA, Young DB (1991). Genetic and immunological analysis of Mycobacterium tuberculosis fibronectin-binding proteins.. Infect Immun, 59(8), 2712 - 2718.
    • Millar AB, Miller RF, Foley NM, Meager A, Semple SJ, Rook GA (1991). Production of tumor necrosis factor-alpha by blood and lung mononuclear phagocytes from patients with human immunodeficiency virus-related lung disease.. Am J Respir Cell Mol Biol, 5(2), 144 - 148. doi:10.1165/ajrcmb/5.2.144
    • ONYEBUJOH P, ROOK G (1991). MYCOBACTERIUM-VACCAE IMMUNOTHERAPY. LANCET, 338(8781), 1534 - 1534.
    • Rook GA (1991). Mobilising the appropriate T-cell subset: the immune response as taxonomist?. Tubercle, 72(4), 253 - 254.
    • Filley EA, Rook GA (1991). Effect of mycobacteria on sensitivity to the cytotoxic effects of tumor necrosis factor.. Infect Immun, 59(8), 2567 - 2572.
    • Rook GA, Taverne J, Playfair JH (1991). Evaluation of TNF as antiviral, antibacterial and antiparasitic agent.. Biotherapy, 3(2), 167 - 175.
    • Lydyard PM, Rook GA, Tsoulfa G, Sharif M, Smith M (1991). Is there a role for mycobacteria in the etiopathogenesis of rheumatoid arthritis?. Immunol Rev, 121, 137 - 154.
    • Rook G, Thompson S, Buckley M, Elson C, Brealey R, Lambert C, White T, Rademacher T (1991). The role of oil and agalactosyl IgG in the induction of arthritis in rodent models.. Eur J Immunol, 21(4), 1027 - 1032. doi:10.1002/eji.1830210425
    • Rook GA, al Attiyah R (1991). Cytokines and the Koch phenomenon.. Tubercle, 72(1), 13 - 20.
    • ROOK GAW, ALATTIYAH R (1991). CYTOKINES AND THE KOCH PHENOMENON - REVIEW. TUBERCLE, 72(1), 13 - 20.
    • Thompson SJ, Butcher PD, Patel VK, Rook GA, Stanford J, van der Zee R, Elson CJ (1991). Modulation of pristane-induced arthritis by mycobacterial antigens.. Autoimmunity, 11(1), 35 - 43.
    • Rook GA, al Attiyah R, Filley E (1991). New insights into the immunopathology of tuberculosis.. Pathobiology, 59(3), 148 - 152.
    • Mattsson R, Mattsson A, Holmdahl R, Whyte A, Rook GA (1991). Maintained pregnancy levels of oestrogen afford complete protection from post-partum exacerbation of collagen-induced arthritis.. Clin Exp Immunol, 85(1), 41 - 47.

    1990

    • ROOK GAW, TAVERNE J, MORENO C (1990). THE ROLE OF TUMOR-NECROSIS-FACTOR IN THE PATHOGENESIS OF TUBERCULOSIS AND LEPROSY, AND THE RELATIONSHIP BETWEEN TISSUE-DAMAGING PATHOLOGY AND PRODUCTION OF AGALACTOSYL IGG.
    • Taverne J, Bate CA, Sarkar DA, Meager A, Rook GA, Playfair JH (1990). Human and murine macrophages produce TNF in response to soluble antigens of Plasmodium falciparum.. Parasite Immunol, 12(1), 33 - 43.
    • Roitt IM, Dwek RA, Parekh RB, Rademacher TW, Warren C, Alavi A, Axford JS, Bodman K, Bond A, Colaco B, Cooke A, Delves PJ, Hay FC, Isenberg DA, Lydyard PM, MacKenzie L, Rook G, Smith M, Sumar N, Tsoulfa G1990 (1990). The significance of changes in IgG carbohydrate in rheumatoid arthritis and tuberculosis.. Advances in Host Defence Mechanisms, 7, 77 - 91.
    • Stanford JL, Rook GA, Bahr GM, Dowlati Y, Ganapati R, Ghazi Saidi K, Lucas S, Ramu G, Torres P, Minh Ly H (1990). Mycobacterium vaccae in immunoprophylaxis and immunotherapy of leprosy and tuberculosis.. Vaccine, 8(6), 525 - 530.
    • BAHR GM, SHAABAN MA, GABRIEL M, ALSHIMALI B, SIDDIQUI Z, CHUGH TD, DENATH FM, SHAHIN A, BEHBEHANI K, CHEDID L, ROOK GAW, STANFORD JL (1990). IMPROVED IMMUNOTHERAPY FOR PULMONARY TUBERCULOSIS WITH MYCOBACTERIUM-VACCAE. TUBERCLE, 71(4), 259 - 266.
    • Thompson SJ, Rook GA, Brealey RJ, Van der Zee R, Elson CJ (1990). Autoimmune reactions to heat-shock proteins in pristane-induced arthritis.. Eur J Immunol, 20(11), 2479 - 2484. doi:10.1002/eji.1830201118
    • Sumar N, Bodman KB, Rademacher TW, Dwek RA, Williams P, Parekh RB, Edge J, Rook GA, Isenberg DA, Hay FC (1990). Analysis of glycosylation changes in IgG using lectins.. J Immunol Methods, 131(1), 127 - 136.
    • Lydyard PM, Tsoulfa G, Sharif M, Bröker B, Smith M, Rook GA (1990). Immunity to heat shock proteins in rheumatoid arthritis.. Clin Exp Rheumatol, 8 Suppl 5, 69 - 74.
    • Foley N, Lambert C, McNicol M, Johnson N, Rook GA (1990). An inhibitor of the toxicity of tumour necrosis factor in the serum of patients with sarcoidosis, tuberculosis and Crohn's disease.. Clin Exp Immunol, 80(3), 395 - 399.
    • Bahr GM, Stanford JL, Chugh TD, Shaaban MA, Gabriel M, al-Shimali B, Siddiqui Z, Ghardani F, Rook GA, Shahin A (1990). An investigation of patients with pulmonary tuberculosis in Kuwait in preparation for studies of immunotherapy with Mycobacterium vaccae.. Tubercle, 71(2), 77 - 86.
    • Rook GA, Foley NM, Meager A (1990). What mediates the immunopathological component of the immune response to Mycobacterium tuberculosis? Can it be switched off?. Bull Int Union Tuberc Lung Dis, 65(2-3), 23 - 26.
    • Stanford JL, Bahr GM, Rook GA, Shaaban MA, Chugh TD, Gabriel M, al-Shimali B, Siddiqui Z, Ghardani F, Shahin A (1990). Immunotherapy with Mycobacterium vaccae as an adjunct to chemotherapy in the treatment of pulmonary tuberculosis.. Tubercle, 71(2), 87 - 93.
    • BAHR GM, YOUSOF AM, MAJEED HAM, BEHBEHANI K, LUBANI M, PAREKH RB, DWEK RA, RADEMACHER TW, YOUNG DB, MEHLERT A, STEELE J, ROOK GAW (1990). AGALACTOSYL IGG, ANTIBODIES TO HEAT-SHOCK PROTEINS, AND ACUTE RHEUMATIC-FEVER. ANN RHEUM DIS, 49(6), 383 - 386.
    • Rook GA (1990). Mycobacteria, cytokines and antibiotics.. Pathol Biol (Paris), 38(4), 276 - 280.
    • Dubé R, Rook GA, Steele J, Brealey R, Dwek R, Rademacher T, Lennard-Jones J (1990). Agalactosyl IgG in inflammatory bowel disease: correlation with C-reactive protein.. Gut, 31(4), 431 - 434.
    • MILLAR AB, MILLER RF, FOLEY NM, ROOK GAW, SEMPLE SJG (1990). TUMOR-NECROSIS-FACTOR (TNF ALPHA) PRODUCTION BY PERIPHERAL-BLOOD MONOCYTES AND ALVEOLAR MACROPHAGES FROM PATIENTS WITH HIV-RELATED LUNG-DISEASE. CLIN SCI, 78(4), P17 - P17.
    • Rook G, Lydyard P, Stanford J (1990). Mycobacteria and rheumatoid arthritis.. Arthritis Rheum, 33(3), 431 - 435.
    • Sharif M, Rook G, Wilkinson LS, Worrall JG, Edwards JC (1990). Terminal N-acetylglucosamine in chronic synovitis.. Br J Rheumatol, 29(1), 25 - 31.
    • Rook GA (1990). The role of activated macrophages in protection and immunopathology in tuberculosis.. Res Microbiol, 141(2), 253 - 256.
    • ROOK GAW (1990). KILLING INTRACELLULAR MYCOBACTERIA - DOGMAS AND REALITIES. RES MICROBIOL, 141(2), 267 - 268.
    • ROOK GAW (1990). THE IMMUNOPATHOLOGY OF TUBERCULOSIS. EOS-RIV IMMUNOL, 10(2), 64 - 68.

    1989

    • Tsoulfa G, Rook GA, Bahr GM, Sattar MA, Behbehani K, Young DB, Mehlert A, Van-Embden JD, Hay FC, Isenberg DA (1989). Elevated IgG antibody levels to the mycobacterial 65-kDa heat shock protein are characteristic of patients with rheumatoid arthritis.. Scand J Immunol, 30(5), 519 - 527.
    • Sharif M, Wilkinson LS, Edwards J, Rook GA (1989). Membrane N-acetylglucosamine: expression by cells in rheumatoid synovial fluid, and by pre-cultured monocytes.. Br J Exp Pathol, 70(5), 567 - 577.
    • Millar AB, Foley NM, Singer M, Johnson NM, Meager A, Rook GA (1989). Tumour necrosis factor in bronchopulmonary secretions of patients with adult respiratory distress syndrome.. Lancet, 2(8665), 712 - 714.
    • Filley E, Andreoli A, Steele J, Waters M, Wagner D, Nelson D, Tung K, Rademacher T, Dwek R, Rook GA (1989). A transient rise in agalactosyl IgG correlating with free interleukin 2 receptors, during episodes of erythema nodosum leprosum.. Clin Exp Immunol, 76(3), 343 - 347.
    • ROOK GAW (1989). THE ROLE OF VITAMIN-D IN TUBERCULOSIS - REPLY. AM REV RESPIR DIS, 139(6), 1571 - 1571.
    • Moreno C, Taverne J, Mehlert A, Bate CA, Brealey RJ, Meager A, Rook GA, Playfair JH (1989). Lipoarabinomannan from Mycobacterium tuberculosis induces the production of tumour necrosis factor from human and murine macrophages.. Clin Exp Immunol, 76(2), 240 - 245.
    • Filley E, Abou-Zeid C, Waters M, Rook G (1989). The use of antigen-bearing nitrocellulose particles derived from Western blots to study proliferative responses to 27 antigenic fractions from Mycobacterium leprae in patients and controls.. Immunology, 67(1), 75 - 80.
    • Bahr GM, Eales LJ, Nye KE, Majeed HA, Yousof AM, Behbehani K, Rook GA (1989). An association between Gc (vitamin D-binding protein) alleles and susceptibility to rheumatic fever.. Immunology, 67(1), 126 - 128.
    • Parekh R, Isenberg D, Rook G, Roitt I, Dwek R, Rademacher T (1989). A comparative analysis of disease-associated changes in the galactosylation of serum IgG.. J Autoimmun, 2(2), 101 - 114.
    • Ghazi Saidi K, Stanford JL, Stanford CA, Dowlati Y, Farshchi Y, Rook GA, Rees RJ (1989). Vaccination and skin test studies on children living in villages with differing endemicity for leprosy and tuberculosis.. Int J Lepr Other Mycobact Dis, 57(1), 45 - 53.
    • Axford JS, Bodman K, Hay FC, Isenberg DA, Lydyard PM, Mackenzie L, Roitt IM, Sumar N, Rook G, Dwek RA (1989). Comment on the article by Tomana et al.. Arthritis Rheum, 32(2), 235 - 236.
    • Tsoulfa G, Rook GA, Van-Embden JD, Young DB, Mehlert A, Isenberg DA, Hay FC, Lydyard PM (1989). Raised serum IgG and IgA antibodies to mycobacterial antigens in rheumatoid arthritis.. Ann Rheum Dis, 48(2), 118 - 123.
    • Leveton C, Barnass S, Champion B, Lucas S, De Souza B, Nicol M, Banerjee D, Rook G (1989). T-cell-mediated protection of mice against virulent Mycobacterium tuberculosis.. Infect Immun, 57(2), 390 - 395.
    • Rook GA, Attiyah RA, Foley N (1989). The role of cytokines in the immunopathology of tuberculosis, and the regulation of agalactosyl IgG.. Lymphokine Res, 8(3), 323 - 328.
    • BAHR GM, SATTAR MA, STANFORD JL, SHAABAN MA, ALSHIMALI B, SIDDIQUI Z, GABRIEL M, ALSAFFAR M, SHAHIN A, CHUGH TD, ROOK GAW, BEHBEHANI K (1989). HLA-DR AND TUBERCULIN TESTS IN RHEUMATOID-ARTHRITIS AND TUBERCULOSIS. ANN RHEUM DIS, 48(1), 63 - 68.
    • Barnes PF, Mehra V, Hirschfield GR, Fong SJ, Abou-Zeid C, Rook GA, Hunter SW, Brennan PJ, Modlin RL (1989). Characterization of T cell antigens associated with the cell wall protein-peptidoglycan complex of Mycobacterium tuberculosis.. J Immunol, 143(8), 2656 - 2662.

    1988

    • ROITT IM, DWEK RA, PAREKH RB, RADEMACHER TW, ALAVI A, AXFORD JS, BODMAN KB, BOND A, COOKE A, HAY FC, ISENBERG DA, LYDYARD PM, MACKENZIE L, ROOK G, SMITH M, SUMAR N (1988). THE ROLE OF ANTIGEN IN AUTOIMMUNE RESPONSES WITH SPECIAL REFERENCE TO CHANGES IN CARBOHYDRATE STRUCTURE OF IGG IN RHEUMATOID-ARTHRITIS. J AUTOIMMUN, 1(6), 499 - 506.
    • Abou-Zeid C, Ratliff TL, Wiker HG, Harboe M, Bennedsen J, Rook GA (1988). Characterization of fibronectin-binding antigens released by Mycobacterium tuberculosis and Mycobacterium bovis BCG.. Infect Immun, 56(12), 3046 - 3051.
    • Bahr GM, Rook GA, al-Saffar M, Van Embden J, Stanford JL, Behbehani K (1988). Antibody levels to mycobacteria in relation to HLA type: evidence for non-HLA-linked high levels of antibody to the 65 kD heat shock protein of M. bovis in rheumatoid arthritis.. Clin Exp Immunol, 74(2), 211 - 215.
    • ROOK GAW (1988). RHEUMATOID-ARTHRITIS, MYCOBACTERIAL ANTIGENS AND AGALACTOSYL IGG. SCAND J IMMUNOL, 28(4), 487 - 493.
    • Rook GA (1988). The role of vitamin D in tuberculosis.. Am Rev Respir Dis, 138(4), 768 - 770. doi:10.1164/ajrccm/138.4.768
    • SHARIF M, WILKINSON I, ROOK G, EDWARDS J (1988). EXPOSURE OF TERMINAL N-ACETYLGLUCOSAMINE IN CHRONIC SYNOVITIS. SCAND J IMMUNOL, 28(4), 507 - 507.
    • Rook GA (1988). Role of activated macrophages in the immunopathology of tuberculosis.. Br Med Bull, 44(3), 611 - 623.
    • Ratliff TL, McGarr JA, Abou-Zeid C, Rook GA, Stanford JL, Aslanzadeh J, Brown EJ (1988). Attachment of mycobacteria to fibronectin-coated surfaces.. J Gen Microbiol, 134(5), 1307 - 1313.
    • Bahr GM, Rook GA, Shahin A, Stanford JL, Sattar MI, Behbehani K (1988). HLA-DR-associated isotype-specific regulation of antibody levels to mycobacteria in rheumatoid arthritis.. Clin Exp Immunol, 72(1), 26 - 31.
    • Roberts D, Katz DR, Mukherjee S, Rook GA (1988). Induction of delayed-type hypersensitivity responses to PPD: dendritic cells in synergy with 5-hydroxytryptamine can substitute for macrophages.. Immunology, 63(4), 697 - 700.
    • Rook GA, Steele J, Rademacher T (1988). A monoclonal antibody raised by immunising mice with group A streptococci binds to agalactosyl IgG from rheumatoid arthritis.. Ann Rheum Dis, 47(3), 247 - 250.
    • FOLEY NM, MILLAR AB, ROOK GAW, JOHNSON NMCI (1988). TUMOR NECROSIS FACTOR RELEASE BY PULMONARY ALVEOLAR MACROPHAGES. THORAX, 43(3), P246 - P247.
    • STANFORD JL, ROOK GAW, BAHR GM, SATTAR I, BEHBEHANI K (1988). HLA-DR AND TUBERCULIN TESTS IN RHEUMATOID-ARTHRITIS - EVIDENCE SUPPORTING A RELATIONSHIP BETWEEN MYCOBACTERIA AND THE ETIOLOGY OF THE DISEASE. DIS MARKERS, 6(1), 63 - 63.
    • ROOK GAW, BAHR GM, STANFORD JL, BEHBEHANI K (1988). HLA AND ANTIBODY TO MYCOBACTERIA IN RHEUMATOID-ARTHRITIS - STRONG ISOTYPE SPECIFIC CORRELATION WITH DR2 AND DR7. DIS MARKERS, 6(1), 63 - 64.
    • AXFORD JS, HAY FC, MACKENZIE L, ISENBERG DA, LYDYARD PM, ROITT IM, ROOK G, RADEMACHER TW, PAREKH RB, DWEK RA (1988). GALACTOSE RESIDUES IN CHRONIC INFLAMMATORY DISEASE - REPLY. LANCET, 1(8582), 418 - 418.
    • Abou-Zeid C, Smith I, Grange JM, Ratliff TL, Steele J, Rook GA (1988). The secreted antigens of Mycobacterium tuberculosis and their relationship to those recognized by the available antibodies.. J Gen Microbiol, 134(2), 531 - 538.
    • Rademacher TW, Parekh RB, Dwek RA, Isenberg D, Rook G, Axford JS, Roitt I (1988). The role of IgG glycoforms in the pathogenesis of rheumatoid arthritis.. Springer Semin Immunopathol, 10(2-3), 231 - 249.
    • Chao LP, Steele J, Rodrigues C, Lennard-Jones J, Stanford JL, Spiliadis C, Rook GA (1988). Specificity of antibodies secreted by hybridomas generated from activated B cells in the mesenteric lymph nodes of patients with inflammatory bowel disease.. Gut, 29(1), 35 - 40.

    1987

    • Abou-Zeid C, Harboe M, Rook GA (1987). Characterization of the secreted antigens of Mycobacterium bovis BCG: comparison of the 46-kilodalton dimeric protein with proteins MPB64 and MPB70.. Infect Immun, 55(12), 3213 - 3214.
    • Abou-Zeid C, Rook GA, Minnikin DE, Parlett JH, Osborn TW, Grange JM (1987). Effect of the method of preparation of bacille Calmette-Guérin (BCG) vaccine on the properties of four daughter strains.. J Appl Bacteriol, 63(5), 449 - 453.
    • Poulter LW, Rook GA, Steele J, Condez A (1987). Influence of 1,25-(OH)2 vitamin D3 and gamma interferon on the phenotype of human peripheral blood monocyte-derived macrophages.. Infect Immun, 55(9), 2017 - 2020.
    • Rook GA (1987). Progress in the immunology of the mycobacterioses.. Clin Exp Immunol, 69(1), 1 - 9.
    • Mahmood KH, Stanford JL, Rook GA, Stuart FA, Pritchard DG, Brewer JI (1987). The immune response in two populations of wild badgers naturally infected with bovine tubercle bacilli.. Tubercle, 68(2), 119 - 125.
    • Rook GA, Taverne J, Leveton C, Steele J (1987). The role of gamma-interferon, vitamin D3 metabolites and tumour necrosis factor in the pathogenesis of tuberculosis.. Immunology, 62(2), 229 - 234.
    • Abou-Zeid C, Filley E, Steele J, Rook GA (1987). A simple new method for using antigens separated by polyacrylamide gel electrophoresis to stimulate lymphocytes in vitro after converting bands cut from Western blots into antigen-bearing particles.. J Immunol Methods, 98(1), 5 - 10.
    • Mahmood KH, Rook GA, Stanford JL, Stuart FA, Pritchard DG (1987). The immunological consequences of challenge with bovine tubercle bacilli in badgers (Meles meles).. Epidemiol Infect, 98(2), 155 - 163. doi:10.1017/S0950268800061860
    • Rook GA, Steele J (1987). Macrophage regulation of vitamin D3 metabolites.. Nature, 326(6108), 21 - 22. doi:10.1038/326021b0
    • Rook GA, Steele J, Ainsworth M, Leveton C (1987). A direct effect of glucocorticoid hormones on the ability of human and murine macrophages to control the growth of M. tuberculosis.. Eur J Respir Dis, 71(4), 286 - 291.
    • Bahr GM, Chugh TD, Behbehani K, Shaaban MA, Abdul-Aty M, Al Shimali B, Siddiqui Z, Gabriel M, Rook GA, Stanford JL (1987). Unexpected findings amongst the skin test responses to mycobacteria of BCG vaccinated Kuwaiti school children.. Tubercle, 68(2), 105 - 112.

    1986

    • Steele J, Flint KC, Pozniak AL, Hudspith B, Johnson MM, Rook GA (1986). Inhibition of virulent Mycobacterium tuberculosis by murine peritoneal macrophages and human alveolar lavage cells: the effects of lymphokines and recombinant gamma interferon.. Tubercle, 67(4), 289 - 294.
    • Rook GA, Steele J, Ainsworth M, Champion BR (1986). Activation of macrophages to inhibit proliferation of Mycobacterium tuberculosis: comparison of the effects of recombinant gamma-interferon on human monocytes and murine peritoneal macrophages.. Immunology, 59(3), 333 - 338.
    • Abou-Zeid C, Smith I, Grange J, Steele J, Rook G (1986). Subdivision of daughter strains of bacille Calmette-Guérin (BCG) according to secreted protein patterns.. J Gen Microbiol, 132(11), 3047 - 3053.
    • Mukherjee S, Katz DR, Rook GA (1986). Differing role of dendritic cells and macrophages in the induction of delayed-type hypersensitivity responses to PPD.. Immunology, 59(2), 229 - 234.
    • Bahr GM, Stanford JL, Rook GA, Rees RJ, Abdelnoor AM, Frayha GJ (1986). Two potential improvements to BCG and their effect on skin test reactivity in the Lebanon.. Tubercle, 67(3), 205 - 218.
    • Bahr GM, Stanford JL, Rook GA, Rees RJ, Frayha GJ, Abdelnoor AM (1986). Skin sensitization to mycobacteria amongst school children prior to a study of BCG vaccination in North Lebanon.. Tubercle, 67(3), 197 - 203.
    • Rook GA, Steele J, Barnass S, Mace J, Stanford JL (1986). Responsiveness to live M. tuberculosis, and common antigens, of sonicate-stimulated T cell lines from normal donors.. Clin Exp Immunol, 63(1), 105 - 110.
    • KATZ DR, MUKHERJEE S, ROBERTS D, ROOK GAW (1986). DIFFERING ROLE OF DENDRITIC CELLS AND MACROPHAGES IN INVIVO RESPONSES TO MYCOBACTERIAL ANTIGENS. J PATHOL, 149(3), A255 - A255.
    • Nye PM, Stanford JL, Rook GA, Lawton P, MacGregor M, Reily C, Humber D, Orege P, Revankar CR, Terencio de las Aguas J (1986). Suppressor determinants of mycobacteria and their potential relevance to leprosy.. Lepr Rev, 57(2), 147 - 157.
    • Rook G (1986). Vitamin D and tuberculosis.. Tubercle, 67(2), 155 - 156.
    • Barnass S, Mace J, Steele J, Torres P, Gervasoni B, Ravioli R, Terencio J, Rook GA, Waters MF (1986). Prevalence and specificity of the enhancing effect of three types of interleukin 2 on T cell responsiveness in 97 lepromatous leprosy patients of mixed ethnic origin.. Clin Exp Immunol, 64(1), 41 - 49.
    • Rook GA, Steele J, Fraher L, Barker S, Karmali R, O'Riordan J, Stanford J (1986). Vitamin D3, gamma interferon, and control of proliferation of Mycobacterium tuberculosis by human monocytes.. Immunology, 57(1), 159 - 163.
    • Rook GA (1986). Gamma interferon and calcitriol formation by human macrophages.. Bioessays, 5(1), 40 - . doi:10.1002/bies.950050112

    1985

    • Andreoli A, Brett SJ, Draper P, Payne SN, Rook GA (1985). Changes in circulating antibody levels to the major phenolic glycolipid during erythema nodosum leprosum in leprosy patients.. Int J Lepr Other Mycobact Dis, 53(2), 211 - 217.
    • Rook GA (1985). Absence from sera from normal individuals or from rifampin-treated leprosy patients (THELEP trials) of antibody to rifamycin-protein or rifamycin-membrane conjugates.. Int J Lepr Other Mycobact Dis, 53(1), 22 - 27.
    • ROOK GAW (1985). NON-REPELLENT BIRD DROPPINGS. NATURE, 318(6043), 237 - 237.
    • Rook GA, Steele J, Umar S, Dockrell HM (1985). A simple method for the solubilisation of reduced NBT, and its use as a colorimetric assay for activation of human macrophages by gamma-interferon.. J Immunol Methods, 82(1), 161 - 167.
    • Rook GA, Champion BR, Steele J, Varey AM, Stanford JL (1985). I-A restricted activation by T cell lines of anti-tuberculosis activity in murine macrophages.. Clin Exp Immunol, 59(2), 414 - 420.
    • Altes C, Steele J, Stanford JL, Rook GA (1985). The effect of lymphokines on the ability of macrophages to protect mycobacteria from a bactericidal antibiotic.. Tubercle, 66(4), 261 - 266.

    1984

    • ROOK GAW, CHAMPION BR, STEELE J, VAREY AM, STANFORD JL (1984). I-A RESTRICTED ACTIVATION BY T-CELL LINES OF ANTI-TUBERCULOSIS ACTIVITY IN MURINE MACROPHAGES. J LEUKOCYTE BIOL, 36(3), 398 - 398.
    • Morton A, Nye P, Rook GA, Samuel N, Stanford JL (1984). A further investigation of skin-test responsiveness and suppression in leprosy patients and healthy school children in Nepal.. Lepr Rev, 55(3), 273 - 281.

    1983

    • van Eden W, de Vries RR, Stanford JL, Rook GA (1983). HLA-DR3 associated genetic control of response to multiple skin tests with new tuberculins.. Clin Exp Immunol, 52(2), 287 - 292.
    • Stanford JL, Rook GA (1983). Protection from infection with mycobacteria.. Indian J Chest Dis Allied Sci, 25(2), 132 - 138.
    • Nye PM, Price JE, Revankar CR, Rook GA, Stanford JL (1983). The demonstration of two types of suppressor mechanism in leprosy patients and their contacts by quadruple skin-testing with mycobacterial reagent mixtures.. Lepr Rev, 54(1), 9 - 18.
    • Rook GA (1983). The immunology of leprosy.. Tubercle, 64(4), 297 - 312.
    • Rook GA (1983). Immunity and hypersensitivity.. Practitioner, 227(1376), iv - vi.
    • ROOK GAW (1983). IMMUNITY AND HYPERSENSITIVITY. PRACTITIONER, 227(1376), R4 - R6.
    • Rook GA (1983). [Importance of recent advances in our understanding of antimicrobial cell-mediated immunity to the International Union for the Prevention of Tuberculosis].. Bull Int Union Tuberc, 58(1), 62 - 72.

    1982

    • Fleming B, Rook GA (1982). T-cell-dependent polyclonal activation by soluble mycobacterial extracts of B cells in peripheral blood mononuclear cell populations from leprosy patients and normal donors.. Immunology, 47(4), 589 - 595.
    • ROOK GAW, RAINBOW S (1982). AN ISOTOPE INCORPORATION ASSAY FOR THE ANTI-MYCOBACTERIAL EFFECTS OF HUMAN-MONOCYTES. ANN INST PASTEUR MIC, B133(1), 169 - 169.
    • Bahr GM, Modabber FZ, Rook GA, Mehrotra ML, Stanford JL, Chedid L (1982). Absence of antibodies to muramyl dipeptide in patients with tuberculosis or leprosy.. Clin Exp Immunol, 47(1), 53 - 58.
    • Rook GA (1982). Suppressor cells of mouse and man. What is the evidence that they contribute to the aetiology of the mycobacterioses?. Lepr Rev, 53(4), 306 - 312.

    1981

    • Stanford JL, Nye PM, Rook GA, Samuel N, Fairbank A (1981). A preliminary investigation of the responsiveness or otherwise of patients and staff of a leprosy hospital to groups of shared or species antigens of mycobacteria.. Lepr Rev, 52(4), 321 - 327.
    • Bahr GM, Rook GA, Stanford JL (1981). Inhibition of the proliferative response of peripheral blood lymphocytes to mycobacterial or fungal antigens by co-stimulation with antigens from various mycobacterial species.. Immunology, 44(3), 593 - 598.
    • Bahr GM, Rook GA, Stanford JL, Lydyard PM, Bryceson AD (1981). The effect of delayed addition of antigen and 'E' rosetting on the proliferative response to mycobacterial antigens of peripheral blood lymphocytes from normal individuals or from patients with tuberculosis or leprosy.. Immunology, 44(3), 585 - 591.
    • Ebringer R, Rook G, Swana GT, Bottazzo GF, Doniach D (1981). Autoantibodies to cartilage and type II collagen in relapsing polychondritis and other rheumatic diseases.. Ann Rheum Dis, 40(5), 473 - 479.
    • Rook GA (1981). Chromosomes for the enzyme-linked immunosorbent assay (ELISA) using horse-radish peroxidase.. Lepr Rev, 52(3), 281 - 283.
    • ROOK GAW (1981). MODULATION OF THE RESPONSE TO PATHOGENIC MYCOBACTERIA BY CONTACT WITH ENVIRONMENTAL SPECIES. J MED MICROBIOL, 14(2), R6 - R6.
    • Stanford JL, Shield MJ, Rook GA (1981). How environmental mycobacteria may predetermine the protective efficacy of BCG.. Tubercle, 62(1), 55 - 62.
    • Rook GA, Bahr GM, Stanford JL (1981). The effect of two distinct forms of cell-mediated response to mycobacteria on the protective efficacy of BCG.. Tubercle, 62(1), 63 - 68.
    • Rook GA, Cameron CH (1981). An inexpensive, portable, battery-operated photometer for the reading of ELISA tests in microtitration plates.. J Immunol Methods, 40(1), 109 - 114.
    • ROOK GAW, STANFORD JL (1981). THE HETEROGENEITY OF THE IMMUNE-RESPONSE TO MYCOBACTERIA AND THE RELEVANCE OF THE COMMON ANTIGENS TO THEIR PATHOGENICITY. ANN INST PASTEUR IMM, D132(2-3), 155 - 164.
    • ROOK GAW, RAINBOW S (1981). AN ISOTOPE INCORPORATION ASSAY FOR THE ANTI-MYCOBACTERIAL EFFECTS OF HUMAN-MONOCYTES. ANN INST PASTEUR IMM, D132(2-3), 281 - 289.
    • Bahr GM, Rook GA, Stanford JL (1981). Prostaglandin-dependent regulation of the in vitro proliferative response to mycobacterial antigens of peripheral blood lymphocytes from normal donors and from patients with tuberculosis or leprosy.. Clin Exp Immunol, 45(3), 646 - 653.

    1980

    • Bahr GM, Rook GA, Moreno E, Lydyard PM, Modabber FZ, Stanford JL (1980). Use of the ELISA to screen for anti-thymocyte and anti-beta 2-microglobulin antibodies in leprosy and SLE.. Immunology, 41(4), 865 - 873.
    • Stanford JL, Rook GA, Samuel N, Madlener F, Khamenei AA, Nemati T, Modabber F, Rees RJ (1980). Preliminary immunological studies in search of correlates of protective immunity carried out on some Iranian leprosy patients and their families.. Lepr Rev, 51(4), 303 - 314.
    • Rook GA (1980). The immunogenicity of killed mycobacteria.. Lepr Rev, 51(4), 295 - 301.

    1979

    • SAMUEL NM, STANFORD JL, ROOK GAW (1979). INVESTIGATION OF MECHANISMS REGULATING SKIN-TEST RESPONSIVENESS IN LEPROSY PATIENTS USING SOLUBLE MYCOBACTERIUM-LEPRAE AND M-TUBERCULOSIS ANTIGENS AND A MIXTURE OF THE 2. INT J LEPROSY, 47(2), 385 - 386.
    • Rook GA, Stanford JL (1979). The relevance to protection of three forms of delayed skin-test response evoked by m. leprae and other mycobacteria in mice. Correlation with the classical work in the guinea-pig.. Parasite Immunol, 1(2), 111 - 123.
    • ROOK GAW, STANFORD JL, SHIELD MJ, SAMUEL NM (1979). CHARACTERIZATION IN MOUSE AND MAN OF 2 DISTINCT FORMS OF DELAYED SKIN-TEST RESPONSE, RELEVANT TO MYCOBACTERIAL INFECTIONS. INT J LEPROSY, 47(2), 377 - 377.
    • STANFORD JL, SHIELD MJ, ROOK GAW (1979). MYCOBACTERIUM-LEPRAE, OTHER MYCOBACTERIA AND A POSSIBLE VACCINE. INT J LEPROSY, 47(2), 357 - 357.
    • SHIELD MJ, STANFORD JL, ROOK GAW (1979). REASON FOR THE REDUCTION OF THE PROTECTIVE EFFICACY OF BCG IN BURMA. INT J LEPROSY, 47(2), 319 - 320.

    1978

    • Rook GA (1978). Three forms of delayed skin-test response evoked by mycobacteria.. Nature, 271(5640), 64 - 65.
    • Rook GA, King J (1978). Is the adherent, non-specific 'suppressor' cell from rodent spleens an in vitro artefact?. Clin Exp Immunol, 32(3), 466 - 470.

    1977

    • SHIELD MJ, STANFORD JL, ROOK GAW (1977). INVESTIGATION OF IMMUNOLOGICAL SPECTRUM OF MYCOBACTERIAL DISEASE IN MAN. J MED MICROBIOL, 10(2), R3 - R3.
    • ROOK GAW, STANFORD JL, SHIELD MJ (1977). INVESTIGATION OF MECHANISMS RESPONSIBLE FOR SPECTRUM OF IMMUNOLOGICAL RESPONSE TO MYCOBACTERIAL DISEASE IN MOUSE. J MED MICROBIOL, 10(2), R3 - R3.

    1976

    • Rook GA, Carswell JW, Stanford JL (1976). Preliminary evidence for the trapping of antigen-specific lymphocytes in the lymphoid tissue of 'anergic' tuberculosis patients.. Clin Exp Immunol, 26(1), 129 - 132.
    • Stanford JL, Rook GA (1976). Taxonomic studies on the leprosy bacillus.. Int J Lepr Other Mycobact Dis, 44(1-2), 216 - 221.
    • Rook GA (1976). Immune responses to mycobacteria in mice and men.. Proc R Soc Med, 69(6), 442 - 444.
    • Rook GA, Stewart-Tull DE (1976). The dissociation of adjuvant properties of mycobacterial components from mitogenicity, and from the ability to induce the release of mediators from macrophages.. Immunology, 31(3), 389 - 396.

    1975

    • Stanford JL, Rook GA, Convit J, Godal T, Kronvall G, Rees RJ, Walsh GP (1975). Preliminary taxonomic studies on the leprosy bacillus.. Br J Exp Pathol, 56(6), 579 - 585.
    • ROOK GAW, KING J (1975). POSSIBLE ROLE OF MACROPHAGE IN SUPPRESSION OF CELL-MEDIATED-IMMUNITY IN SEVERE MYCOBACTERIAL INFECTIONS. J MED MICROBIOL, 8(2), PR9 - PR9.
    • Rook GA (1975). The immunological consequences of antigen overload in experimental mycobacterial infections of mice.. Clin Exp Immunol, 19(1), 167 - 177.
    • Rook GA (1975). The potentiating, mitogenic and inhibitory effects on lymphocytes in vitro, of macrophages in the lymph nodes of mice 'overloaded' with mycobacterial products.. Clin Exp Immunol, 21(1), 163 - 172.

    1973

    • ROOK GAW (1973). IS MACROPHAGE SITE OF IMMUNOSUPPRESSIVE ACTION OF RIFAMPICIN. TUBERCLE, 54(4), 291 - 295.
    • Rook GA (1973). Is the macrophage the site of the immunosuppressive action of rifampicin?. Tubercle, 54(4), 291 - 295.

    1970

    • Rook GA, Webb HE (1970). Antilymphocyte serum and tissue culture used to investigate role of cell-mediated response in viral encephalitis in mice.. Br Med J, 4(5729), 210 - 212.

    1968

    • Rook GA, Cater DB (1968). The effect of lymph-node cells from specifically sensitised mice, on the growth of the BP8 ascites tumor "in vivo" and "in vitro".. Br J Exp Pathol, 49(3), 241 - 250.

    1964

    • SANTOPADRE G, RUSCHI A, BENDINELLI M, ROOK GA (1964). [ON THE ANTIBODY RESPONSE TO ANTIPOLIOMYELITIC VACCINE (SABIN TYPE) IN A GROUP OF CHILDREN OF THE PROVINCE OF PISA].. Riv Ital Ig, 24, 571 - 582.

    • Rook GAW, Hernandez-Pando R, Zumla A (). Tuberculosis due to high-dose challenge in partially immune individuals:a problem for vaccination?. The Journal of Infectious Diseases, , - .
    • Rook GAW, Doherty TM (). Host susceptibility and resistance to M.tuberculosis:. In Zumla A, Schaaf A (Ed.), Genetic neuroendocrine and acquired factors (pp. - ). : Elsevier.
    • Rook GAW (). The broader implications of the hygiene hypothesis. Immunology, , - .