Dr Richard Milne

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Personal Profile

Name: Richard Milne Email: richard.milne@ucl.ac.uk
Title: Dr Tel:
Department: Research Department of Infection Fax:
Position: Lecturer Address: Department of Virology, UCL Medical School, Royal Free Campus, Rowland Hill Street, London, NW3 2PF
Research Domain: Experimental Medicine, Infection Immunology & Inflammation Web Page:  

Profile

Research Description

Virus entry Virus receptor interactions Virus trafficking Immune response to herpes infection

Research Activities

CMV Pathogenesis and Development of Vaccines

herpesviruses

Education Description

UCL Collaborators

Prof Paul Griffiths; Prof Richard Tedder; Prof Caroline Sabin; Prof Deenan Pillay; Prof Paul Kellam

External Collaborators

Publications

    2012

    • Marashi SM, Raeiszadeh M, Enright V, Tahami F, Workman S, Chee R, Webster AD, Milne RS, Emery VC (2012). Influence of cytomegalovirus infection on immune cell phenotypes in patients with common variable immunodeficiency.. J Allergy Clin Immunol, 129(5), 1349 - 1356.e3. doi:10.1016/j.jaci.2012.02.011
    • Atabani SF, Smith C, Atkinson C, Aldridge RW, Rodriguez-Perálvarez M, Rolando N, Harber M, Jones G, O'Riordan A, Burroughs AK, Thorburn D, O'Beirne J, Milne RS, Emery VC, Griffiths PD (2012). Cytomegalovirus replication kinetics in solid organ transplant recipients managed by preemptive therapy.. Am J Transplant, 12(9), 2457 - 2464. doi:10.1111/j.1600-6143.2012.04087.x

    2011

    • Emery VC, Milne RSB (2011). Recent developments in antiviral drugs for cytomegalovirus. FUTURE VIROL, 6(5), 633 - 651. doi:10.2217/FVL.11.30
    • Marashi SM, Raeiszadeh M, Workman S, Rahbar A, Soderberg-Naucler C, Klenerman P, Chee R, Webster AD, Milne RS, Emery VC (2011). Inflammation in common variable immunodeficiency is associated with a distinct CD8(+) response to cytomegalovirus.. J Allergy Clin Immunol, 127(6), 1385 - 93.e4. doi:10.1016/j.jaci.2011.04.001
    • Griffiths PD, Stanton A, McCarrell E, Smith C, Osman M, Harber M, Davenport A, Jones G, Wheeler DC, O'Beirne J, Thorburn D, Patch D, Atkinson CE, Pichon S, Sweny P, Lanzman M, Woodford E, Rothwell E, Old N, Kinyanjui R, Haque T, Atabani S, Luck S, Prideaux S, Milne RS, Emery VC, Burroughs AK (2011). Cytomegalovirus glycoprotein-B vaccine with MF59 adjuvant in transplant recipients: a phase 2 randomised placebo-controlled trial.. Lancet, 377(9773), 1256 - 1263. doi:10.1016/S0140-6736(11)60136-0
    • Griffiths PD, Milne RSB (2011). Intracellular neutralisation of adenovirus by antibody. REV MED VIROL, 21(1), 1 - 2. doi:10.1002/rmv.675

    2010

    • Lagos D, Pollara G, Henderson S, Gratrix F, Fabani M, Milne RS, Gotch F, Boshoff C (2010). miR-132 regulates antiviral innate immunity through suppression of the p300 transcriptional co-activator.. Nat Cell Biol, 12(5), 513 - 519. doi:10.1038/ncb2054

    2008

    • Stiles KM, Milne RS, Cohen GH, Eisenberg RJ, Krummenacher C (2008). The herpes simplex virus receptor nectin-1 is down-regulated after trans-interaction with glycoprotein D.. Virology, 373(1), 98 - 111.

    2006

    • Whitbeck JC, Zuo Y, Milne RS, Cohen GH, Eisenberg RJ (2006). Stable association of herpes simplex virus with target membranes is triggered by low pH in the presence of the gD receptor, HVEM.. Journal of Virology, 80(8), 3773 - 3780. doi:10.1128/JVI.79.11.6655-6663.2005
    • Whitbeck JC, Zuo Y, Milne RSB, Cohen GH, Eisenberg RJ (2006). Stable association of herpes simplex virus with target membranes is triggered by low pH in the presence of the gD receptor, HVEM. J VIROL, 80(8), 3773 - 3780. doi:10.1128/JVI.80.8.3773-3780.2006

    2005

    • Milne RS, Nicola AV, Whitbeck JC, Eisenberg RJ, Cohen GH (2005). Glycoprotein D receptor-dependent, low-pH-independent endocytic entry of herpes simplex virus type 1.. Journal of Virology, 79(11), 6655 - 6663. doi:10.1128/JVI.79.11.6655-6663-2005

    2003

    • Cairns TM, Milne RS, Ponce-de-Leon M, Tobin DK, Cohen GH, Eisenberg RJ (2003). Structure-function analysis of herpes simplex virus type 1 gD and gH-gL: clues from gDgH chimeras.. Journal of Virology, 77(12), 6731 - 6742.
    • Milne RS, Hanna SL, Rux AH, Willis SH, Cohen GH, Eisenberg RJ (2003). Function of herpes simplex virus type 1 gD mutants with different receptor-binding affinities in virus entry and fusion.. Journal of Virology, 77(16), 8962 - 8972. doi:10.1128/JVI.77.16.8962-8972.2003

    2002

    • Paterson DA, Dyer AP, Milne RSB, Sevilla-Reyes E, Gompels UA (2002). A role for human cytomegalovirus glycoprotein O (gO) in cell fusion and a new hypervariable locus. VIROLOGY, 293(2), 281 - 294. doi:10.1006/viro.2001.1274

    2001

    • Milne RSB, Connolly SA, Krummenacher C, Eisenberg RJ, Cohen GH (2001). Porcine HveC, a member of the highly conserved HveC/Nectin 1 family, is a functional alphaherpesvirus receptor. VIROLOGY, 281(2), 315 - 328. doi:10.1006/viro.2000.0798

    2000

    • Zal B, Pinto-Basto J, Milne R, Jeeachee M, Baboonian C (2000). Immunological analysis of the tegument phosphoprotein ppUL83 of human cytomegalovirus. J Virol Methods, 85(1-2), 183 - 192.
    • Milne RSB, Mattick C, Nicholson L, Devaraj P, Alcami A, Gompels UA (2000). RANTES binding and down-regulation by a novel human herpesvirus-6 beta chemokine receptor. J IMMUNOL, 164(5), 2396 - 2404.

    1998

    • Milne RSB, Paterson DA, Booth JC (1998). Human cytomegalovirus glycoprotein H glycoprotein L complex modulates fusion-from-without. J GEN VIROL, 79, 855 - 865.

    1976

    • Milne RS, Randall DJ (1976). Regulation of arterial pH during fresh water to sea water transfer in the rainbow trout Salmo gairdneri.. Comp Biochem Physiol A Comp Physiol, 53(2), 157 - 160.