Dr Simon Eaton

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Personal Profile

Name: Simon Eaton Email: s.eaton@ucl.ac.uk
Title: Dr Tel: 2079052158
Department: ICH - Stem Cells & Regenerative Medicine Fax: 2074046181
Position: Senior Lecturer Address: Institute of Child Health, 30 Guilford Street, London, WC1N 1EH
Research Domain: Personalised Medicine, Populations & Lifelong Health, Reproduction & Development Web Page: Personal Web Page

Profile

Research Description

My current research interests are centred on the biochemical and metabolic responses to surgery and critical illness in infants and children. To these ends, we have established an active research group in the Paediatric Surgery unit undertaking a variety of basic science and applied clinical investigations. Recently, we have run several multi-centre and single-centre randomised clinical trials in Paediatric Surgery. I have also established a stable-isotope facility in the Institute of Child Health to undertake nutritional and body composition studies.

Research Activities

Better understand normal and abnormal development of the neuromuscular components of the gastrointestinal tract.

Development of novel stem cell-based therapies for aganglionic gut disorders

Development of the enteric neuromusculature

Novel therapies for gut disorders/diseases

Education Description

UCL Collaborators

Dr Suwan Jayasinghe; Dr Richard Day; Dr Paolo De Coppi; Dr Steven Howe; Dr Nikhil Thapar; Dr Alan Burns

External Collaborators

Publications

    2014

    • Maghsoudlou P, Eaton S, De Coppi P (2014). Tissue engineering of the esophagus.. Semin Pediatr Surg, 23(3), 127 - 134. doi:10.1053/j.sempedsurg.2014.04.003
    • Hall NJ, Eaton S, Seims A, Leys CM, Densmore JC, Calkins CM, Ostlie DJ, St Peter SD, Azizkhan RG, von Allmen D, Langer JC, Lapidus-Krol E, Bouchard S, Piché N, Bruch S, Drongowski R, MacKinlay GA, Clark C, Pierro A (2014). Risk of incomplete pyloromyotomy and mucosal perforation in open and laparoscopic pyloromyotomy.. J Pediatr Surg, 49(7), 1083 - 1086. doi:10.1016/j.jpedsurg.2013.10.014
    • Evennett N, Cerigioni E, Hall NJ, Pierro A, Eaton S (2014). Smooth muscle actin as a novel serologic marker of severe intestinal damage in rat intestinal ischemia-reperfusion and human necrotising enterocolitis.. J Surg Res, , - . doi:10.1016/j.jss.2014.04.020
    • Carnaghan H, Pereira S, James CP, Charlesworth PB, Ghionzoli M, Mohamed E, Cross KM, Kiely E, Patel S, Desai A, Nicolaides K, Curry JI, Ade-Ajayi N, De Coppi P, Davenport M, David AL, Pierro A, Eaton S (2014). Is early delivery beneficial in gastroschisis?. J Pediatr Surg, 49(6), 928 - 933. doi:10.1016/j.jpedsurg.2014.01.027
    • Mushtaq I, Garriboli M, Smeulders N, Cherian A, Desai D, Eaton S, Duffy P, Cuckow P (2014). Primary bladder exstrophy closure in neonates: challenging the traditions.. J Urol, 191(1), 193 - 198. doi:10.1016/j.juro.2013.07.020
    • Hughes SD, Kanabus M, Anderson G, Hargreaves IP, Rutherford T, O'Donnell M, Cross JH, Rahman S, Eaton S, Heales SJ (2014). The ketogenic diet component decanoic acid increases mitochondrial citrate synthase and complex I activity in neuronal cells.. J Neurochem, , - . doi:10.1111/jnc.12646
    • Zani A, Cananzi M, Lauriti G, Fascetti-Leon F, Pierro A, Eaton S, De Coppi P, Wells J, Siow B, Lythgoe MF (2014). Amniotic fluid stem cells prevent development of ascites in a neonatal rat model of necrotizing enterocolitis. European Journal of Pediatric Surgery, 24(1), 57 - 60. doi:10.1055/s-0033-1350059
    • Zani A, Cananzi M, Fascetti-Leon F, Lauriti G, Smith VV, Bollini S, Ghionzoli M, D'Arrigo A, Pozzobon M, Piccoli M, Hicks A, Wells J, Siow B, Sebire NJ, Bishop C, Leon A, Atala A, Lythgoe MF, Pierro A, Eaton S, De Coppi P (2014). Amniotic fluid stem cells improve survival and enhance repair of damaged intestine in necrotising enterocolitis via a COX-2 dependent mechanism.. Gut, 63(2), 300 - 309. doi:10.1136/gutjnl-2012-303735
    • Pacilli M, Eaton S, McHoney M, Kiely EM, Drake DP, Curry JI, Lindley KJ, Pierro A (2014). Four year follow-up of a randomised controlled trial comparing open and laparoscopic Nissen fundoplication in children.. Arch Dis Child, , - . doi:10.1136/archdischild-2013-304279

    2013

    • Gordon-smith SB, Eaton S, Ursu S, Wedderburn LR (2013). Lymphocytes from the inflamed joint of Juvenile Idiopathic Arthritis patients express reduced levels of CD73 and have a functional defect in adenosine production.
    • Garriboli M, Bishay M, Kiely EM, Drake DP, Curry JI, Cross KM, Eaton S, De Coppi P, Pierro A (2013). Recurrence rate of Morgagni diaphragmatic hernia following laparoscopic repair.. Pediatr Surg Int, 29(2), 185 - 189. doi:10.1007/s00383-012-3199-y
    • Hallal PC, Reichert FF, Clark VL, Cordeira KL, Menezes AM, Eaton S, Ekelund U, Wells JC (2013). Energy expenditure compared to physical activity measured by accelerometry and self-report in adolescents: a validation study.. PLoS One, 8(11), e77036 - . doi:10.1371/journal.pone.0077036
    • Carnaghan H, Roberts T, Savery D, Norris F, McCann CJ, Copp AJ, Scambler P, Lythgoe M, Greene NDE, DeCoppi P, Burns A, Pierro A, Eaton S (2013). Novel exomphalos genetic mouse model: the importance of accurate phenotypic characterisation.. Journal of Pediatric Surgery, 48(10), 2036 - 2042. doi:10.1016/j.jpedsurg.2013.04.010.
    • Lauriti G, Zani A, Aufieri R, Cananzi M, Chiesa PL, Eaton S, Pierro A (2013). Incidence, Prevention, and Treatment of Parenteral Nutrition-Associated Cholestasis and Intestinal Failure-Associated Liver Disease in Infants and Children: A Systematic Review.. JPEN J Parenter Enteral Nutr, , - . doi:10.1177/0148607113496280
    • Eaton S, Thyoka M, Pierro A, Sebire N (2013). Histologic and Immunohistochemical Features Associated with Outcome in Neonatal Necrotizing Enterocolitis. European Journal of Pediatric Surgery, , - . doi:10.1055/s-0033-1349716
    • Nielsen SB, Wells JC, Fewtrell MS, Eaton S, Grinham J, Reilly JJ (2013). Validation of energy requirement references for exclusively breast-fed infants.. Br J Nutr, 109(11), 2036 - 2043. doi:10.1017/S000711451200428X
    • Maghsoudlou P, Georgiades F, Tyraskis A, Totonelli G, Loukogeorgakis SP, Orlando G, Shangaris P, Lange P, Delalande JM, Burns AJ, Cenedese A, Sebire NJ, Turmaine M, Guest BN, Alcorn JF, Atala A, Birchall MA, Elliott MJ, Eaton S, Pierro A, Gilbert TW, De Coppi P (2013). Preservation of micro-architecture and angiogenic potential in a pulmonary acellular matrix obtained using intermittent intra-tracheal flow of detergent enzymatic treatment.. Biomaterials, 34(28), 6638 - 6648. doi:10.1016/j.biomaterials.2013.05.015
    • Bishay M, Giacomello L, Retrosi G, Thyoka M, Garriboli M, Brierley J, Harding L, Scuplak S, Cross KM, Curry JI, Kiely EM, De Coppi P, Eaton S, Pierro A (2013). Hypercapnia and acidosis during open and thoracoscopic repair of congenital diaphragmatic hernia and esophageal atresia: results of a pilot randomized controlled trial.. Ann Surg, 258(6), 895 - 900. doi:10.1097/SLA.0b013e31828fab55
    • Singh RR, Eaton S, Cross KM, Curry JI, De Coppi P, Kiely EM, Roebuck DJ, Pierro A (2013). Management of a complication of percutaneous gastrostomy in children.. Eur J Pediatr Surg, 23(1), 76 - 79. doi:10.1055/s-0032-1330844
    • Totonelli G, Maghsoudlou P, Georgiades F, Garriboli M, Koshy K, Turmaine M, Ashworth M, Sebire NJ, Pierro A, Eaton S, De Coppi P (2013). Detergent enzymatic treatment for the development of a natural acellular matrix for oesophageal regeneration.. Pediatr Surg Int, 29(1), 87 - 95. doi:10.1007/s00383-012-3194-3
    • Thyoka M, Barnacle A, Chippington S, Eaton S, Drake DP, Cross KM, De Coppi P, Kiely EM, Pierro A, Curry JI, Roebuck DJ (2013). Fluoroscopic Balloon Dilation of Esophageal Atresia Anastomotic Strictures in Children and Young Adults: Single-Center Study of 103 Consecutive Patients from 1999 to 2011.. Radiology, , 122184 - . doi:10.1148/radiol.13122184
    • Franzin C, Piccoli M, Serena E, Bertin E, Urbani L, Luni C, Pasqualetto V, Eaton S, Elvassore N, De Coppi P, Pozzobon M (2013). Single cell PCR analysis of murine embryonic stem cells cultured on different substrates highlights heterogeneous expression of stem cell markers.. Biol Cell, , - . doi:10.1111/boc.201300034
    • Hall NJ, Eaton S, Pierro A (2013). Necrotizing enterocolitis: Prevention, treatment, and outcome.. J Pediatr Surg, 48(12), 2359 - 2367. doi:10.1016/j.jpedsurg.2013.08.006
    • Aylett SB, Neergheen V, Hargreaves IP, Eaton S, Land JM, Rahman S, Heales SJ (2013). Levels of 5-methyltetrahydrofolate and ascorbic acid in cerebrospinal fluid are correlated: Implications for the accelerated degradation of folate by reactive oxygen species. Neurochem.Int., , - . doi:10.1016/j.neuint.2013.10.002
    • Maghsoudlou P, Totonelli G, Loukogeorgakis SP, Eaton S, De Coppi P (2013). A decellularization methodology for the production of a natural acellular intestinal matrix.. J Vis Exp, (80), - . doi:10.3791/50658
    • Eaton S, Zani A, Pierro A, De Coppi P (2013). Stem cells as a potential therapy for necrotizing enterocolitis.. Expert Opin Biol Ther, , - . doi:10.1517/14712598.2013.849690
    • Eaton S, Hall NJ (2013). The potential of probiotics in the fight against necrotizing enterocolitis.. Expert Rev Gastroenterol Hepatol, 7(7), 581 - 583. doi:10.1586/17474124.2013.827480
    • Zani A, Eaton S, Hoellwarth M, Puri P, Tovar J, Fasching G, Bagolan P, Lukac M, Wijnen R, Kuebler J, Cecchetto G, Rintala R, Pierro A (2013). Management of Pediatric Inguinal Hernias in the Era of Laparoscopy: Results of an International Survey.. Eur J Pediatr Surg, , - . doi:10.1055/s-0033-1354586
    • Ghionzoli M, Repele A, Sartiani L, Costanzi G, Parenti A, Spinelli V, David AL, Garriboli M, Totonelli G, Tian J, Andreadis ST, Cerbai E, Mugelli A, Messineo A, Pierro A, Eaton S, De Coppi P (2013). Human amniotic fluid stem cell differentiation along smooth muscle lineage.. FASEB J, , - . doi:10.1096/fj.12-218578
    • Zani A, Eaton S, Hoellwarth ME, Puri P, Tovar J, Fasching G, Bagolan P, Lukac M, Wijnen R, Kuebler JF, Cecchetto G, Rintala R, Pierro A (2013). International Survey on the Management of Esophageal Atresia.. Eur J Pediatr Surg, , - . doi:10.1055/s-0033-1350058
    • Repele A, Lupi R, Eaton S, Urbani L, De Coppi P, Campanella M (2013). Cell metabolism sets the differences between subpopulations of satellite cells (SCs).. BMC Cell Biol, 14, 24 - . doi:10.1186/1471-2121-14-24
    • Kubiak R, Eaton S, Andrews J, Grant HW (2013). Long-Term Catch-Up Weight Gain Following Fundoplication in Children. EUROPEAN JOURNAL OF PEDIATRIC SURGERY, 23(2), 121 - 126. doi:10.1055/s-0032-1324801
    • Duberley KE, Hargreaves IP, Chaiwatanasirikul KA, Heales SJ, Land JM, Rahman S, Mills K, Eaton S (2013). Coenzyme Q10 quantification in muscle, fibroblasts and cerebrospinal fluid by liquid chromatography/tandem mass spectrometry using a novel deuterated internal standard.. Rapid Commun Mass Spectrom, 27(9), 924 - 930. doi:10.1002/rcm.6529
    • Eaton S, Klein N, Ong E, Pierro A (2013). Authors' reply: Randomized clinical trial of glutamine-supplemented versus standard parenteral nutrition in infants with surgical gastrointestinal disease (Br J Surg 2012; 99: 929-938).. Br J Surg, 100(6), 841 - 842. doi:10.1002/bjs.9126
    • Eaton S (2013). Combining data from multiple studies: an introduction to meta-analysis in paediatric surgery.. J Pediatr Surg, 48(2), 281 - 287. doi:10.1016/j.jpedsurg.2012.11.004
    • Bishay M, Lakshminarayanan B, Arnaud A, Garriboli M, Cross KM, Curry JI, Drake D, Kiely EM, De Coppi P, Pierro A, Eaton S (2013). The role of parenteral nutrition following surgery for duodenal atresia or stenosis.. Pediatr Surg Int, 29(2), 191 - 195. doi:10.1007/s00383-012-3200-9
    • Owino V, Kasonka L, Wells J, Eaton S, Sinkala M, Tomkins A, Darch T, Filteau S (2013). BREAST MILK INTAKE OF 9-MONTH OLD ZAMBIAN INFANTS GIVEN FORTIFIED COMPLEMENTARY FOODS. ANNALS OF NUTRITION AND METABOLISM, 63, 554 - 554.

    2012

    • Totonelli G, Maghsoudlou P, Fishman JM, Orlando G, Ansari T, Sibbons P, Birchall MA, Pierro A, Eaton S, De Coppi P (2012). Esophageal tissue engineering: a new approach for esophageal replacement.. World J Gastroenterol, 18(47), 6900 - 6907. doi:10.3748/wjg.v18.i47.6900
    • Mead EL, Mosley A, Eaton S, Dobson L, Heales SJ, Pocock JM (2012). Microglial neurotransmitter receptors trigger superoxide production in microglia; consequences for microglial-neuronal interactions.. J Neurochem, 121(2), 287 - 301. doi:10.1111/j.1471-4159.2012.07659.x
    • Garriboli M, Eaton S, Pierro A, De Coppi P (2012). More patches or more lung in congenital diaphragmatic hernia?. Journal of Pediatric Surgery, 47(10), 1968 - 1969. doi:10.1016/j.jpedsurg.2012.06.025
    • Garriboli M, Duess JW, Ruttenstock E, Bishay M, Eaton S, De Coppi P, Puri P, Höllwarth ME, Pierro A (2012). Trends in the treatment and outcome of congenital diaphragmatic hernia over the last decade. Pediatric Surgery International, , 1 - 5.
    • Duberley KEC, Hargreaves IP, Chaiwatanasirikul K, Heales SJ, Rahman S, Mills K, Eaton S (2012). DEVELOPMENT OF A MASS SPECTROMETRY METHOD (MS/MS) FOR QUANTIFICATION OF COENZYME Q10 IN CSF.
    • Wells JC, Jonsdottir OH, Hibberd PL, Fewtrell MS, Thorsdottir I, Eaton S, Lucas A, Gunnlaugsson G, Kleinman RE (2012). Randomized controlled trial of 4 compared with 6 mo of exclusive breastfeeding in Iceland: differences in breast-milk intake by stable-isotope probe.. Am J Clin Nutr, 96(1), 73 - 79. doi:10.3945/ajcn.111.030403
    • Ghionzoli M, James CP, David AL, Shah D, Tan AW, Iskaros J, Drake DP, Curry JI, Kiely EM, Cross K, Eaton S, De Coppi P, Pierro A (2012). Gastroschisis with intestinal atresia--predictive value of antenatal diagnosis and outcome of postnatal treatment.. J Pediatr Surg, 47(2), 328 - 328. doi:10.1016/j.jpedsurg.2011.11.022
    • Heywood W, Wang D, Madgett TE, Avent ND, Eaton S, Chitty LS, Mills K (2012). The development of a peptide SRM-based tandem mass spectrometry assay for prenatal screening of Down syndrome.. J Proteomics, 75(11), 3248 - 3257. doi:10.1016/j.jprot.2012.03.037
    • Sim R, Hall NJ, de Coppi P, Eaton S, Pierro A (2012). Core temperature falls during laparotomy in infants with necrotizing enterocolitis.. Eur J Pediatr Surg, 22(1), 45 - 49. doi:10.1055/s-0031-1284360
    • Ghionzoli M, James CP, David AL, Shah D, Tan AW, Iskaros J, Drake DP, Curry JI, Kiely EM, Cross K, Eaton S, De Coppi P, Pierro A (2012). Gastroschisis with intestinal atresia--predictive value of antenatal diagnosis and outcome of postnatal treatment.. J Pediatr Surg, 47(2), 322 - 328. doi:10.1016/j.jpedsurg.2011.11.022
    • Totonelli G, Maghsoudlou P, Garriboli M, Riegler J, Orlando G, Burns AJ, Sebire NJ, Smith VV, Fishman JM, Ghionzoli M (2012). A rat decellularized small bowel scaffold that preserves villus-crypt architecture for intestinal regeneration. Biomaterials, 33(12), 3401 - 3410. doi:10.1016/j.biomaterials.2012.01.012
    • Aylett S-B, Neergheen V, Eaton S, Land JM, Rahman S, Heales SJ (2012). FACTORS AFFECTING 5-METHYLTETRAHYDROFOLATE (5MTHF) STABILITY: IMPLICATIONS FOR CEREBRAL 5MTHF DEFICIENCY.
    • Hall NJ, Choi W, Pierro A, Eaton S (2012). Age-related probability of contralateral processus vaginalis patency in children with unilateral inguinal hernia.. Pediatr Surg Int, 28(11), 1085 - 1088. doi:10.1007/s00383-012-3174-7
    • Choi W, Hall NJ, Garriboli M, Ron O, Curry JI, Cross K, Drake DP, Kiely EM, Eaton S, De Coppi P, Pierro A (2012). Outcomes following laparoscopic inguinal hernia repair in infants compared with older children. Pediatric Surgery International, , 1 - 5.
    • Svensson JF, Hall NJ, Eaton S, Pierro A, Wester T (2012). A Review of Conservative Treatment of Acute Appendicitis. EUROPEAN JOURNAL OF PEDIATRIC SURGERY, 22(3), 185 - 194. doi:10.1055/s-0032-1320014
    • Heslegrave AJ, Kapoor RR, Eaton S, Chadefaux B, Akcay T, Simsek E, Flanagan SE, Ellard S, Hussain K (2012). Leucine-sensitive hyperinsulinaemic hypoglycaemia in patients with loss of function mutations in 3-Hydroxyacyl-CoA Dehydrogenase.. Orphanet J Rare Dis, 7(1), 25 - . doi:10.1186/1750-1172-7-25
    • Pacilli M, Eaton S, Clarke A, Whitehead A, Nagy A, Brain JL (2012). Clinical significance of eosinophilia and chronic inflammatory infiltrate in children's rectal biopsies.. J Pediatr Gastroenterol Nutr, 55(5), 519 - 522. doi:10.1097/MPG.0b013e31825b3169
    • Padidela R, Bennett K, Nessa A, Wells J, Aufieri R, James C, Smith VV, Brain C, Eaton S, Hussain K (2012). Severe resistance to weight gain, lack of stored triglycerides in adipose tissue, hypoglycaemia, and increased energy expenditure: a novel disorder of energy homeostasis.. Horm Res Paediatr, 77(4), 261 - 268. doi:10.1159/000337248
    • Ong EG, Eaton S, Wade AM, Horn V, Losty PD, Curry JI, Sugarman ID, Klein NJ, Pierro A, SIGN Trial Group (2012). Randomized clinical trial of glutamine-supplemented versus standard parenteral nutrition in infants with surgical gastrointestinal disease.. Br J Surg, 99(7), 929 - 938. doi:10.1002/bjs.8750
    • Carrington EV, Hall NJ, Pacilli M, Drake DP, Curry JI, Kiely EM, De Coppi P, Pierro A, Eaton S (2012). Cost-effectiveness of laparoscopic versus open pyloromyotomy.. J Surg Res, 178(1), 315 - 320. doi:10.1016/j.jss.2012.01.031
    • Thyoka M, Eaton S, Hall NJ, Drake D, Kiely E, Curry J, Cross K, de Coppi P, Pierro A (2012). Advanced necrotizing enterocolitis part 2: recurrence of necrotizing enterocolitis.. Eur J Pediatr Surg, 22(1), 13 - 16. doi:10.1055/s-0032-1306264
    • Thyoka M, de Coppi P, Eaton S, Khoo K, Hall NJ, Curry J, Kiely E, Drake D, Cross K, Pierro A (2012). Advanced necrotizing enterocolitis part 1: mortality.. Eur J Pediatr Surg, 22(1), 8 - 12. doi:10.1055/s-0032-1306263
    • Macharia EW, Eaton S, de Coppi P, Curry J, Drake D, Cross K, Kiely E, Pierro A (2012). Fundoplication in ventilator-dependent infants with gastro-oesophageal reflux.. Eur J Pediatr Surg, 22(1), 91 - 96. doi:10.1055/s-0032-1306265
    • Nah SA, de Coppi P, Kiely EM, Curry JI, Drake DP, Cross K, Spitz L, Eaton S, Pierro A (2012). Duhamel pull-through for Hirschsprung disease: a comparison of open and laparoscopic techniques.. J Pediatr Surg, 47(2), 308 - 312. doi:10.1016/j.jpedsurg.2011.11.025
    • Bishay M, Pichler J, Horn V, Macdonald S, Ellmer M, Eaton S, Hill S, Pierro A (2012). Intestinal failure-associated liver disease in surgical infants requiring long-term parenteral nutrition.. J Pediatr Surg, 47(2), 359 - 362. doi:10.1016/j.jpedsurg.2011.11.032
    • Bishay M, Retrosi G, Horn V, Cloutman-Green E, Harris K, de Coppi P, Klein N, Eaton S, Pierro A (2012). Septicaemia due to enteric organisms is a later event in surgical infants requiring parenteral nutrition.. Eur J Pediatr Surg, 22(1), 50 - 53. doi:10.1055/s-0031-1287853
    • Carnaghan H, Johnson H, Eaton S, de Coppi P, Curry J, Morova M, Cross K, Drake D, Kiely E, Pierro A (2012). Effectiveness of the antegrade colonic enema stopper at preventing stomal stenosis: long-term follow-up.. Eur J Pediatr Surg, 22(1), 26 - 28. doi:10.1055/s-0031-1285874
    • Totonelli G, Maghsoudlou P, Garriboli M, Georgiades F, Delalande JM, Thapar N, Pierro A, Eaton S, Burns AJ, De Coppi P (2012). Recellularization of a natural intestinal matrix using chicken chorioallantoic membrane as an in vivo bioreactor.

    2011

    • Nielsen SB, Reilly JJ, Fewtrell MS, Eaton S, Grinham J, Wells JC (2011). Adequacy of milk intake during exclusive breastfeeding: a longitudinal study.. Pediatrics, 128(4), e907 - e914. doi:10.1542/peds.2011-0914
    • Pacilli M, Eaton S, Fell JM, Rawat D, Clarke S, Haddad MJ (2011). Surgery in children with Crohn disease refractory to medical therapy.. J Pediatr Gastroenterol Nutr, 52(3), 286 - 290. doi:10.1097/MPG.0b013e3181e999af
    • Wells JC, Haroun D, Williams JE, Darch T, Eaton S, Viner R, Fewtrell MS (2011). Evaluation of lean tissue density for use in air displacement plethysmography in obese children and adolescents.. Eur J Clin Nutr, 65(10), 1094 - 1101. doi:10.1038/ejcn.2011.76
    • Zani A, Nah SA, Ron O, Totonelli G, Ismail D, Smith VV, Ashworth M, Blankenstein O, Mohnike W, De Coppi P, Eaton S, Hussain K, Pierro A (2011). The predictive value of preoperative fluorine-18-L-3,4-dihydroxyphenylalanine positron emission tomography-computed tomography scans in children with congenital hyperinsulinism of infancy.. J Pediatr Surg, 46(1), 204 - 208. doi:10.1016/j.jpedsurg.2010.09.093
    • Retrosi G, Bishay M, Kiely EM, Sebire NJ, Anderson J, Elliott M, Drake DP, Coppi PD, Eaton S, Pierro A (2011). Morbidity after ganglioneuroma excision: is surgery necessary?. Eur J Pediatr Surg, 21(1), 33 - 37. doi:10.1055/s-0030-1263195
    • Nah SA, Giacomello L, Eaton S, de Coppi P, Curry JI, Drake DP, Kiely EM, Pierro A (2011). Surgical repair of incarcerated inguinal hernia in children: laparoscopic or open?. Eur J Pediatr Surg, 21(1), 8 - 11. doi:10.1055/s-0030-1262793
    • McHoney M, Wade AM, Eaton S, Howard RF, Kiely EM, Drake DP, Curry JI, Pierro A (2011). Clinical outcome of a randomized controlled blinded trial of open versus laparoscopic Nissen fundoplication in infants and children.. Ann Surg, 254(2), 209 - 216. doi:10.1097/SLA.0b013e318226727f
    • Hall NJ, Eaton S, Pierro A (2011). Editorial on "Open versus laparoscopic pyloromyotomy for pyloric stenosis: a meta-analysis of randomized controlled trials" by Jia et al.. Eur J Pediatr Surg, 21(2), 75 - 76. doi:10.1055/s-0031-1275323
    • Hall NJ, Ron O, Eaton S, Pierro A (2011). Surgery for hydrocele in children-an avoidable excess?. J Pediatr Surg, 46(12), 2401 - 2405. doi:10.1016/j.jpedsurg.2011.07.029
    • Eaton S (2011). Protecting the bowel of premature infants.. Br J Nutr, 106(6), 793 - 794. doi:10.1017/S0007114511001280
    • Thyoka M, Eaton S, Kiely EM, Curry JI, Drake DP, Cross KM, Hall NJ, Khoo AK, De Coppi P, Pierro A (2011). Outcomes of diverting jejunostomy for severe necrotizing enterocolitis.. J Pediatr Surg, 46(6), 1041 - 1044. doi:10.1016/j.jpedsurg.2011.03.024
    • Bishay M, Retrosi G, Horn V, Cloutman-Green E, Harris K, De Coppi P, Klein N, Eaton S, Pierro A (2011). Chlorhexidine antisepsis significantly reduces the incidence of sepsis and septicemia during parenteral nutrition in surgical infants.. J Pediatr Surg, 46(6), 1064 - 1069. doi:10.1016/j.jpedsurg.2011.03.028
    • Moncrieffe H, Nistala K, Eaton S, Wedderburn LR (2011). A novel defect: CD39+T cells are enriched in the inflamed joint but do not suppress. CLIN EXP RHEUMATOL, 29(2), 376 - 376.
    • Hall NJ, Jones CE, Eaton S, Stanton MP, Burge DM (2011). Is interval appendicectomy justified after successful nonoperative treatment of an appendix mass in children? A systematic review.. J Pediatr Surg, 46(4), 767 - 771. doi:10.1016/j.jpedsurg.2011.01.019
    • Bishay M, Giacomello L, Retrosi G, Thyoka M, Nah SA, McHoney M, De Coppi P, Brierley J, Scuplak S, Kiely EM, Curry JI, Drake DP, Cross KM, Eaton S, Pierro A (2011). Decreased cerebral oxygen saturation during thoracoscopic repair of congenital diaphragmatic hernia and esophageal atresia in infants.. J Pediatr Surg, 46(1), 47 - 51. doi:10.1016/j.jpedsurg.2010.09.062
    • Retrosi G, Sebire NJ, Bishay M, Kiely EM, Anderson J, De Coppi P, Resca E, Rampling D, Bier N, Mills K, Eaton S, Pierro A (2011). Brain lipid-binding protein: a marker of differentiation in neuroblastic tumors.. J Pediatr Surg, 46(6), 1197 - 1200. doi:10.1016/j.jpedsurg.2011.03.053

    2010

    • Barry SP, Lawrence KM, McCormick J, Soond SM, Hubank M, Eaton S, Sivarajah A, Scarabelli TM, Knight RA, Thiemermann C, Latchman DS, Townsend PA, Stephanou A (2010). New targets of urocortin-mediated cardioprotection.. J Mol Endocrinol, 45(2), 69 - 85. doi:10.1677/JME-09-0148
    • Hall NJ, Eaton S, Peters MJ, Hiorns MP, Alexander N, Azzopardi DV, Pierro A (2010). Mild controlled hypothermia in preterm neonates with advanced necrotizing enterocolitis.. Pediatrics, 125(2), e300 - e308. doi:10.1542/peds.2008-3211
    • Rees CM, Eaton S, Khoo AK, Kiely EM, Members of NET Trial Group , Pierro A (2010). Peritoneal drainage does not stabilize extremely low birth weight infants with perforated bowel: data from the NET Trial.. J Pediatr Surg, 45(2), 324 - 328. doi:10.1016/j.jpedsurg.2009.10.066
    • Ghionzoli M, Cananzi M, Zani A, Rossi CA, Leon FF, Pierro A, Eaton S, De Coppi P (2010). Amniotic fluid stem cell migration after intraperitoneal injection in pup rats: implication for therapy.. Pediatr Surg Int, 26(1), 79 - 84. doi:10.1007/s00383-009-2504-x
    • Rees CM, Eaton S, Pierro A (2010). National prospective surveillance study of necrotizing enterocolitis in neonatal intensive care units.. J Pediatr Surg, 45(7), 1391 - 1397. doi:10.1016/j.jpedsurg.2009.12.002
    • Haroun D, Taylor SJ, Viner RM, Hayward RS, Darch TS, Eaton S, Cole TJ, Wells JC (2010). Validation of bio-electrical impedance analysis in adolescents across different ethnic groups. Obesity, 18, 1252 - 1259.
    • McHoney M, Eaton S, Wade A, Carnielli V, Kiely E, Drake D, Curry J, Pierro A (2010). Effect of laparoscopy and laparotomy on energy and protein metabolism in children: a randomized controlled trial.. J Pediatr, 157(3), 439 - 444.e2. doi:10.1016/j.jpeds.2010.02.067
    • Moncrieffe H, Nistala K, Kamhieh Y, Evans J, Eddaoudi A, Eaton S, Wedderburn LR (2010). High expression of the ectonucleotidase CD39 on T cells from the inflamed site identifies two distinct populations, one regulatory and one memory T cell population.. J Immunol, 185(1), 134 - 143. doi:10.4049/jimmunol.0803474
    • Evennett NJ, Hall NJ, Pierro A, Eaton S (2010). Urinary intestinal fatty acid-binding protein concentration predicts extent of disease in necrotizing enterocolitis.. J Pediatr Surg, 45(4), 735 - 740. doi:10.1016/j.jpedsurg.2009.09.024
    • McHoney M, Giacomello L, Nah SA, De Coppi P, Kiely EM, Curry JI, Drake DP, Eaton S, Pierro A (2010). Thoracoscopic repair of congenital diaphragmatic hernia: intraoperative ventilation and recurrence.. J Pediatr Surg, 45(2), 355 - 359. doi:10.1016/j.jpedsurg.2009.10.072
    • Zani A, Ghionzoli M, Lauriti G, Cananzi M, Smith VV, Pierro A, De Coppi P, Eaton S (2010). Does intestinal permeability lead to organ failure in experimental necrotizing enterocolitis?. Pediatr Surg Int, 26(1), 85 - 89. doi:10.1007/s00383-009-2507-7
    • Pierro A, Eaton S, Rees CM, De Coppi P, Kiely EM, Peters MJ, Brierley J (2010). Is there a benefit of peritoneal drainage for necrotizing enterocolitis in newborn infants?. J Pediatr Surg, 45(11), 2117 - 2118. doi:10.1016/j.jpedsurg.2010.09.001
    • Wells JC, Williams JE, Wilson C, Darch T, Viner RM, Eaton S, Fewtrell MS (2010). Evaluation of DXA against the four-component model of body composition in obese children and adolescents aged 5 to 21 years. International Journal of Obesity, 34(4), 649 - 655.

    2009

    • Haroun D, Croker H, Viner RM, Williams JE, Darch TS, Fewtrell MS, Eaton S, Wells JC (2009). Validation of BIA in Obese Children and Adolescents and Re-evaluation in a Longitudinal Study. Obesity (Silver.Spring), 17(12), 2245 - 2250.
    • Eaton S, McHoney M, Giacomello L, Pacilli M, Bishay M, De Coppi P, Wood J, Cohen R, Pierro A (2009). Carbon dioxide absorption and elimination in breath during minimally invasive surgery. J BREATH RES, 3(4), - . doi:10.1088/1752-7155/3/4/047005
    • Lauriti G, Cananzi M, Pierro A, Eaton S, De Coppi P (2009). Intestinal Ischemia-reperfusion Injury Causes Activation of Bone Marrow-derived Progenitor Cells. European Journal of Pediatric Surgery, 19(6), 366 - 369.
    • Evennett N, Alexander N, Petrov M, Pierro A, Eaton S (2009). A systematic review of serologic tests in the diagnosis of necrotizing enterocolitis.. J Pediatr Surg, 44(11), 2192 - 2201. doi:10.1016/j.jpedsurg.2009.07.028
    • Lauriti G, Cananzi M, Pierro A, Eaton S, de CP (2009). Intestinal ischemia-reperfusion injury causes activation of. Eur J Pediatr Surg, 19(6), 366 - 369.
    • Eaton S, Hall NJ, Pierro A (2009). Zero-total event trials and incomplete pyloromyotomy. J PEDIATR SURG, 44(12), 2434 - 2435. doi:10.1016/j.jpedsurg.2009.08.028
    • Hall NJ, Eaton S, Pierro A (2009). The evidence base for neonatal surgery. Early Human Development, 85(11), 713 - 718.
    • McHoney M, Eaton S, Pierro A (2009). Metabolic response to surgery in infants and children. European Journal of Pediatric Surgery, 19(5), 275 - 285.
    • Garrett-Cox RG, Stefanutti G, Booth C, Klein NJ, Pierro A, Eaton S (2009). Glutamine decreases inflammation in infant rat endotoxemia. J Pediatr Surg, 44(3), 523 - 529.
    • Garrett-Cox RG, Stefanutti G, Booth C, Klein NJ, Pierro A, Eaton S (2009). Glutamine decreases inflammation in infant rat endotoxemia.. J Pediatr Surg, 44(3), 523 - 529. doi:10.1016/j.jpedsurg.2008.09.007
    • Kimura Y, Pierro A, Eaton S (2009). Glutathione synthesis in intestinal ischaemia-reperfusion injury: effects of moderate hypothermia. J Pediatr Surg, 44(2), 353 - 357.
    • Hall NJ, Pacilli M, Eaton S, Reblock K, Gaines BA, Pastor A, Langer JC, Koivusalo AI, Pakarinen MP, Stroedter L, Beyerlein S, Haddad M, Clarke S, Ford H, Pierro A (2009). Recovery after open versus laparoscopic pyloromyotomy for pyloric stenosis: a double-blind multicentre randomised controlled trial. Lancet, 373(9661), 390 - 398.
    • Kapoor RR, James C, Flanagan SE, Ellard S, Eaton S, Hussain K (2009). 3-Hydroxyacyl-Coenzyme A Dehydrogenase Deficiency and Hyperinsulinemic Hypoglycemia: Characterization of a Novel Mutation and Severe Dietary Protein Sensitivity. Journal of Clinical Endocrinology and Metabolism, 94(7), 2221 - 2225.
    • Zani A, Cananzi M, Eaton S, Pierro A, De Coppi P (2009). Stem cells as a potential treatment of necrotizing enterocolitis. Journal of Pediatric Surgery, 44(3), 659 - 660.
    • Alexander N, Eaton S, Haston M, Wallace AS, Smith VV, Burns AJ, Salomon J, Shah N, Klein NJ, Pierro A, Thapar N (2009). Hirschsprung's disease associated enterocolitis is related to defects in innate immunity.

    2008

    • Zani A, Eaton S, Leon FF, Malerba A, Hall NJ, De Coppi P, Smith VV, Pierro A (2008). Captopril reduces the severity of bowel damage in a neonatal rat model of necrotizing enterocolitis.. J Pediatr Surg, 43(2), 308 - 314. doi:10.1016/j.jpedsurg.2007.10.022
    • Chandarana KA, Eaton SJ, Morgan MY (2008). Slow-release carbohydrates: A rational, patientacceptable approach for the nutritional management of patients with cirrhosis?.
    • Khoo AK, Hall NJ, Alexander N, Evennett NJ, Pierro A, Eaton S (2008). Plasma soluble e-selectin in necrotising enterocolitis.. Eur J Pediatr Surg, 18(6), 419 - 422. doi:10.1055/s-2008-1038908
    • Pacilli M, Pierro A, Lindley KJ, Curry JI, Eaton S (2008). Gastric emptying is accelerated following laparoscopic Nissen fundoplication.. Eur J Pediatr Surg, 18(6), 395 - 397. doi:10.1055/s-2008-1038919
    • Pierro A, Eaton S (2008). Metabolism and nutrition in the surgical neonate.. Semin Pediatr Surg, 17(4), 276 - 284. doi:10.1053/j.sempedsurg.2008.07.006
    • Hall NJ, Hiorns M, Tighe H, Peters M, Khoo AK, Eaton S, Pierro A (2008). Is Necrotizing Enterocolitis Associated with Development or Progression of Intraventricular Hemorrhage?. Am J Perinatol., , - .
    • Eaton S, Pacilli M, Wood J, McHoney M, Corizia L, Kingsley C, Curry JI, Herod J, Cohen R, Pierro A (2008). Factors affecting 13C-natural abundance measurement of breath carbon dioxide during surgery: absorption of carbon dioxide during endoscopic procedures.. Rapid Commun Mass Spectrom, 22(11), 1759 - 1762. doi:10.1002/rcm.3572
    • Stefanutti G, Pierro A, Parkinson EJ, Smith VV, Eaton S (2008). Moderate hypothermia as a rescue therapy against intestinal ischemia and reperfusion injury in the rat.. Crit Care Med, 36(5), 1564 - 1572. doi:10.1097/CCM.0b013e3181709e9f
    • Mavri-Damelin D, Damelin LH, Eaton S, Rees M, Selden C, Hodgson HJF (2008). Cells for bioartificial liver devices: The human hepatoma-derived cell line C3A produces urea but does not detoxify ammonia. BIOTECHNOL BIOENG, 99(3), 644 - 651. doi:10.1002/bit.21599
    • Zani A, Eaton S, Leon FF, Malerba A, Hall NJ, De CP, Smith VV, Pierro A (2008). Captopril reduces the severity of bowel damage in a neonatal rat model of necrotizing enterocolitis. J Pediatr Surg., 43(2), 308 - 314.
    • Mavri-Damelin D, Damelin LH, Eaton S, Rees M, Selden C, Hodgson HJF (2008). Cells for bioartificial liver devices: The human hepatoma-derived cell line C3A produces urea but does not detoxify ammonia. Biotechnology and Bioengineering, 99(3), 644 - 651.
    • Rees CM, Eaton S, Kiely EM, Wade AM, McHugh K, Pierro A (2008). Peritoneal drainage or laparotomy in neonatal bowel perforation? A randomised controlled trial. Ann.Surg., 248(1), 44 - 51.
    • Zani A, Eaton S, Rees CM, Pierro A (2008). Incidentally detected Meckel diverticulum - To resect or not to resect?. Annals of Surgery, 247(2), 276 - 281.
    • Piastra M, Di Rocco C, Caresta E, Zorzi G, De Luca D, Caldarelli M, La Torre G, Conti G, Antonelli M, Eaton S, Pietrini D (2008). Blood loss and short-term outcome of infants undergoing brain tumour removal. Journal of Neuro-Oncology, 90(2), 191 - 200.
    • Zani A, Cordischi L, Cananzi M, De Coppi P, Smith VV, Eaton S, Pierro A (2008). Assessment of a neonatal rat model of necrotizing enterocolitis.. Eur J Pediatr Surg, 18(6), 423 - 426. doi:10.1055/s-2008-1038951

    2007

    • Bhattacharya K, Orton RC, Qi X, Mundy H, Morley DW, Champion MP, Eaton S, Tester RF, Lee PJ (2007). A novel starch for the treatment of glycogen storage diseases. J INHERIT METAB DIS, 30(3), 350 - 357. doi:10.1007/s10545-007-0479-0
    • Coelho R, Wells J, Smyth J, Semple R, O'Rahilly S, Eaton S, Hussain K (2007). Severe hypoinsulinaemic hypoglycaemia in a premature infant associated with poor weight gain and reduced adipose tissue. Hormone Research, 68, 91 - 98.
    • Owino VO, Kasonka LM, Sinkala MM, Wells JK, Eaton S, Darch T, Coward A, Tomkins AM, Filteau SM (2007). Fortified complementary foods with or without {alpha}-amylase treatment increase hemoglobin but do not reduce breast milk intake of 9 month old Zambian infants. American Journal of Clinical Nutrition, 86, 1094 - 1103.
    • Ron O, Eaton S, Pierro A (2007). Systematic review of the risk of developing a metachronous contralateral inguinal hernia in children. British Journal of Surgery, 94(7), 804 - 811. doi:10.1002/bjs.5856
    • Ron O, Eaton S, Pierro A (2007). Systematic review of the risk of developing a metachronous contralateral inguinal hernia in children.. Br J Surg, 94(7), 804 - 811. doi:10.1002/bjs.5856
    • Stefanutti G, Pierro A, Smith VV, Klein NJ, Eaton S (2007). Peroxynitrite decomposition catalyst FeTMPyP provides partial protection against intestinal ischemia and reperfusion injury in infant rats.. Pediatr Res, 62(1), 43 - 48. doi:10.1203/PDR.0b013e31806790c0
    • Caresta E, Pierro A, Chowdhury M, Peters MJ, Piastra M, Eaton S (2007). Oxidation of intravenous lipid in infants and children with systemic inflammatory response syndrome and sepsis. Pediatric Research, 61(2), 228 - 232. doi:10.1203/01.pdr.0000252441.91671.e5
    • Mavri-Damelin D, Eaton S, Damelin LH, Rees M, Hodgson HJ, Selden C (2007). Ornithine transcarbamylase and arginase I deficiency are responsible for diminished urea cycle function in the human hepatoblastoma cell line HepG2.. Int J Biochem Cell Biol, 39(3), 555 - 564. doi:10.1016/j.biocel.2006.10.007
    • Piastra M, Caresta E, Zorzi G, De Luca D, Pietrini D, Conti G, Pierro A, Di Rocco C, Eaton S (2007). Early increase of lipid peroxidation in surgically induced brain injury: a possible target for neuroprotection?. ACTA PAEDIATR, 96, 124 - 124.
    • Stefanutti G, Pierro A, Smith VV, Klein NJ, Eaton S (2007). Peroxynitrite decomposition catalyst FeTMPyP provides partial protection against intestinal ischaemia and reperfusion injury in infant rats. Pediatric Research, 62(1), 43 - 48. doi:10.1203/PDR.0b013e31806790c0
    • Pacilli M, Eaton S, Maritsi D, Lopez PJ, Spitz L, Kiely EM, Drake DP, Curry JI, Pierro A (2007). Factors predicting failure of redo Nissen fundoplication in children. Pediatr.Surg.Int., 23(5), 499 - 503.

    2006

    • McCormick J, Barry SP, Sivarajah A, Stefanutti G, Townsend PA, Lawrence KM, Eaton S, Knight RA, Thiemermann C, Latchman DS, Stephanou A (2006). Free radical scavening inhibits STAT phosphorylation following in vivo ischaemia/reperfusion injury. The FASEB Journal, 20(12), 2115 - 2117. doi:10.1096/fj.06-6188fje
    • McHoney MC, Corizia L, Eaton S, Wade A, Spitz L, Drake DP, Kiely EM, Tan HL, Pierro A (2006). Laparoscopic surgery in children is associated with an intraoperative hypermetabolic response. SURG ENDOSC, 20(3), 452 - 457.
    • Muqit MMK, Abou-Sleiman PM, Saurin AT, Harvey K, Gandhi S, Deas E, Eaton S, Payne Smith MD, Venner K, Matilla A, Healy DG, Gilks WP, Lees AJ, Holton J, Revesz T, Parker PJ, Harvey RJ, Wood NW, Latchman DS (2006). Altered cleavage and localisation of PINK1 to aggresomes in the presence of proteasomal stress. Journal of Neurochemistry, 98, 156 - 159. doi:10.1111/j.1471-4159.2006.03845.x
    • Pacilli M, Pierro A, Kingsley C, Curry JI, Herod J, Eaton S (2006). Absorption of carbon dioxide during laparoscopy in children measured using a novel mass spectrometric technique. British Journal of Anaesthesia, 97 (2), 215 - 219.
    • Rees CM, Pierro A, Eaton S (2006). Neurodevelopmental outcomes of neonates with medically and surgically treated necrotizing enterocolitis. Arch.Dis.Child Fetal Neonatal Ed, , - .
    • Muller WG, Morini F, Eaton S, Peters M, Jaffe A (2006). Safety and feasibility of exhaled breath condensate collection in ventilated infants and children. EUR RESPIR J, 28(3), 479 - 485.
    • Pacilli M, Pierro A, Kingsley C, Curry JI, Herod J, Eaton S (2006). Absorption of carbon dioxide during laparoscopy in children measured using a novel mass spectrometric technique.. Br J Anaesth, 97(2), 215 - 219. doi:10.1093/bja/ael134
    • Eaton S (2006). The biochemical basis of antioxidant therapy in critical illness.. Proc Nutr Soc, 65(3), 242 - 249.
    • Hussain K, Clayton PT, Krywawych S, Chatziandreou I, Mills P, Ginbey DW, Geboers AJ, Berger R, van D, Eaton S (2006). RP408.
    • Mavri-Damelin D, Eaton S, Coward S, Damelin L, Rees M, Selden C, Hodgson HJF (2006). Restoring urea cycle function in HepG2 cells by multiple gene transfer; A cell source for a bio-artificial liver device.
    • Pierro A, Eaton S (2006). Nutrition in the neonatal surgical patient. In Thureen P, Hay W (Ed.), Neonatal Nutrition and Metabolism (pp. 569 - 585). : Cambridge University Press.
    • Wade A, Pan H, Eaton S, Pierro A, Ong E (2006). An investigation of minimisation criteria. BMC MED RES METHODOL, 6, 11 - .
    • McHoney M, Klein NJ, Eaton S, Pierro A (2006). Decreased monocyte class II MHC expression following major abdominal surgery in children is related to operative stress. Pediatric Surgery International, 22(4), 330 - 334.
    • Pierro A, Eaton S, Ong E (2006). Neonatal Physiology and Metabolic Considerations. In Grosveld JL, O'Neill JA, Fonkalsrud EW, Coran AG (Ed.), Pediatric Surgery (pp. 89 - 113). : Mosby Elsevier.
    • Mavri-Damelin D, Eaton S, Coward S, Damelin L, Rees M, Selden C, Hodgson HJF (2006). Restoring urea cycle function in HepG2 cells by multiple gene transfer; A cell source for a bio-artificial liver device. Journal of Hepatology, 44, S144 - S144.
    • Geoghegan M, McAuley D, Eaton S, Powell-Tuck J (2006). Selenium in critical illness. Current Opinion in Critical Care, 12(2), 136 - 141.

    2005

    • Duncan AJ, Heales SJR, Mills K, Eaton S, Land JM, Hargreaves IP (2005). Determination of coenzyme q10 status in blood mononuclear cells, skeletal muscle, and plasma by HPLC with di-propoxy-coenzyme q10 as an internal standard. Clinical Chemistry, 51(12), 2380 - 2381. doi:10.1373/clinchem.2005.054643
    • Parkinson EJ, Lawrence KM, Latchman DS, Eaton S, Pierro A (2005). Modulation by hypothermia of hepatic gene expression following intestinal ischaemia-reperfusion. P NUTR SOC, 64, 22A - 22A.
    • Chowdhury M, Eaton S, Peters MJ, Klein NJ, Goldman A, Pierro A (2005). Promotion of monocyte HLA-DR expression and attenuation of cytokine response by glutamine supplementation in septic children. P NUTR SOC, 64, 16A - 16A.
    • McHoney M, Carnielli VP, Eaton S, Howard R, Kiely EM, Drake DP, Spitz L, Pierro A (2005). Differential effects of laparoscopic and open surgery on post-operative protein metabolism. P NUTR SOC, 64, 10A - 10A.
    • Mills K, Eaton S, Ledger V, Young E, Winchester B (2005). The synthesis of internal standards for the quantitative determination of sphingolipids by tandem mass spectrometry. RAPID COMMUN MASS SPECTROM, 19(12), 1739 - 1748.
    • Eaton S, Pierro A (2005). Carnitine and Fatty acid Oxidation in Sepsis. Chemical Monthly, 136, 1483 - 1492.
    • Rees CM, Hall NJ, Eaton S, Pierro A (2005). Surgical strategies for necrotising enterocolitis: a survey of practice in the United Kingdom.. Arch Dis Child Fetal Neonatal Ed, 90(2), F152 - F155. doi:10.1136/adc.2004.051862
    • Stefanutti G, Lister P, Smith VV, Peters MJ, Klein NJ, Pierro A, Eaton S (2005). P-selectin expression, neutrophil infiltration, and histologic injury in neonates with necrotizing enterocolitis.. J Pediatr Surg, 40(6), 942 - 947. doi:10.1016/j.jpedsurg.2005.03.027
    • McHoney M, Eaton S, Wade A, Klein NJ, Stefanutti G, Booth C, Kiely EM, Curry JI, Drake DP, Pierro A (2005). Inflammatory response in children after laparoscopic vs open Nissen fundoplication: randomized controlled trial.. J Pediatr Surg, 40(6), 908 - 913. doi:10.1016/j.jpedsurg.2005.03.003
    • Hall NJ, Smith VV, Harding B, Pierro A, Eaton S (2005). Intestinal Ischemia-Reperfusion Injury Does not Lead to Acute Central Nervous System Damage. J SURG RES, 129, 288 - 291.
    • Stefanutti G, Pierro A, Vinardi S, Spitz L, Eaton S (2005). Moderate hypothermia protects against systemic oxidative stress in a rat model of intestinal ischemia and reperfusion injury.. Shock, 24(2), 159 - 164.
    • Stefanutti G, Pierro A, Vinardi S, Spitz L, Eaton S (2005). Moderate hypothermia protects against systemic oxidative stress in a rat model of intestinal ischemia and reperfusion injury. Shock, 24(2), 159 - 164. doi:10.1097/01.shk.0000168871.60531.6f
    • Hargreaves IP, Duncan A, Mills K, Eaton S, Land JM, Heales SJR (2005). Blood mononuclear cell, but not plasma coenzyme Q(10) concentration correlates with skeletal muscle levels: implications for diagnosis and treatment.
    • Hall NJ, Peters M, Eaton S, Pierro A (2005). Association of hyperglycaemia with increased morbidity and mortality in neonates with necrotising enterocolitis. P NUTR SOC, 64, 7A - 7A.
    • Hussain K, Clayton PT, Krywawych S, Chatziandreou I, Mills P, Ginbey DW, Geboers AJJM, Berger R, van den Berg IET, Eaton S (2005). Hyperinsulinism of infancy associated with a novel splice site mutation in the short-chain 3-hydroxyacyl-CoA dehydrogenase gene. The Journal of Pediatrics, 146(5), 706 - 708.
    • Caresta E, Pierro A, Chowdhury M, Peters MJ, Petros AJ, Piastra M, Eaton S (2005). Intravenous lipid utilisation in infants and children with sepsis and systemic inflammatory response syndrome. P NUTR SOC, 64, 6A - 6A.
    • Hall NJ, Ali J, Pierro A, Eaton S (2005). Total glutathione is not decreased in infants with necrotizing enterocolitis.. J Pediatr Surg, 40(5), 769 - 773. doi:10.1016/j.jpedsurg.2005.01.039
    • Hussain K, Clayton PT, Krywawych S, Chatziandreou I, Mills P, Ginbey DW, Geboers AJJM, Berger R, Van den Berg IET, Eaton S (2005). Hyperinsulinism of infancy associated with a novel splice site mutation in the SCHAD gene. J PEDIATR, 146(5), 706 - 708. doi:10.1016/j.jpeds.2005.01.032

    2004

    • Basile M, Romeo C, Gitto E, Spitz L, Pierro A, Eaton S (2004). Melatonin protects from, but does not reverse, the effects of mediators of sepsis on liver bioenergetics. Pediatric Surgery International, 20(4), 263 - 266.
    • Bartlett K, Eaton S (2004). Mitochondrial beta-oxidation. European Journal of Biochemistry, 271(3), 462 - 469.
    • Pierro A, Eaton S (2004). Nutrition in the neonatal surgical patient. In Hay WW, Thureen PJ (Ed.), Neonatal Nutrition and Metabolism (pp. - ). : Cambridge University Press.
    • Stefanutti G, Vejchapipat P, Williams SR, Pierro A, Eaton S (2004). Heart energy metabolism after intestinal ischaemia and reperfusion.. J Pediatr Surg, 39(2), 179 - 183.
    • Pierro A, Eaton S (2004). Intestinal ischemia reperfusion injury and multisystem organ failure. SEM PEDIATR SURG, 13(1), 11 - 17.
    • Fukumoto K, Pierro A, Zammit VA, Spitz L, Eaton S (2004). Tyrosine nitration of carnitine palmitoyl transferase I during endotoxaemia in suckling rats. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1683(1-3), 1 - 6. doi:10.1016/j.bbalip.2004.03.006
    • Stefanutti G, Vejchapipat P, Williams SR, Pierro A, Eaton S (2004). Heart energy metabolism after intestinal ischaemia and reperfusion. Journal of Pediatric Surgery, 39, 179 - 183.
    • Lawrence KM, Townsend PA, Davidson SM, Carroll CJ, Eaton S, Hubank M, Knight RA, Stephanou A, Latchman DS (2004). The cardioprotective effect of urocortin during ischaemia/reperfusion involves the prevention of mitochondrial damage. Biochemical and Biophysical Research Communications, 321(2), 479 - 486.
    • Parkinson EJ, Townsend PA, Stephanou A, Latchman DS, Eaton S, Pierro A (2004). The protective effect of moderate hypothermia during intestinal ischemia-reperfusion is associated with modification of hepatic transcription factor activation. Journal of Pediatric Surgery, 39(5), 696 - 701.
    • Eaton S, Hall N, Rees CM, Pierro A (2004). Necrotizing enterocolitis: pathogenesis, medical management and surgery. British Journal of Intensive Care, 14(3), 101 - 105.
    • Eaton S, Pierro A (2004). Glutathione in Systemic Inflammation and Sepsis. British Journal of Intensive Care, 14, 53 - 59.
    • Hall NJ, Peters M, Eaton S, Pierro A (2004). Hyperglycemia is associated with increased morbidity and mortality rates in neonates with necrotizing enterocolitis. Journal of Pediatric Surgery, 39(6), 898 - 901.

    2003

    • Eaton S, Fukumoto K, Stefanutti G, Spitz L, Zammit VA, Pierro A (2003). Myocardial carnitine palmitoyltransferase I as a target for oxidative modification in inflammation and sepsis. Biochemical Society Transactions, 31(Pt 6), 1133 - 1136.
    • Vinardi S, Pierro A, Parkinson EJ, Vejchapipat P, Stefanutti G, Spitz L, Eaton S (2003). Hypothermia throughout intestinal ischaemia-reperfusion injury attenuates lung neutrophil infiltration.. J Pediatr Surg, 38(1), 88 - 91. doi:10.1053/jpsu.2003.50017
    • Fukumoto K, Pierro A, Spitz L, Eaton S (2003). Neonatal endotoxemia affects heart but not kidney bioenergetics. Journal of Pediatric Surgery, 38(5), 690 - 693.
    • Ragazzi S, Pierro A, Peters M, Fasoli L, Eaton S (2003). Early full blood count and severity of disease in neonates with necrotizing enterocolitis. Pediatric Surgery International, 19(5), 376 - 379.
    • Fukumoto K, Pierro A, Spitz L, Eaton S (2003). Cardiac and renal mitochondria respond differently to hydrogen peroxide in suckling rats. Journal Of Surgical Research, 113(1), 146 - 150.
    • Eaton S, Chatziandreou I, Krywawych S, Pen S, Clayton PT, Hussain K (2003). Short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency associated with hyperinsulinism: a novel glucose-fatty acid cycle?. Biochemical Society Transactions, 31(Pt 6), 1137 - 1139.
    • Eaton S (2003). Impaired energy metabolism during neonatal sepsis: the effects of glutamine. Proceedings of the Nutrition Society, 62(3), 745 - 751.
    • Hussain K, Eaton S, Clayton P (2003). Exogenous administered DL- sodium beta-hydroxybutyrate (beta-OHB) can cross the blood brain barrier. Pediatric Research, 53(5), 865 - 866.
    • Garrett-Cox RG, Pierro A, Spitz L, Eaton S (2003). Body temperature and heat production in suckling rat endotoxaemia: beneficial effects of glutamine. Journal of Pediatric Surgery, 38(1), 37 - 44.
    • McHoney M, Corizia L, Eaton S, Kiely EM, Drake DP, Tan HL, Spitz L, Pierro A (2003). Carbon dioxide elimination during laparoscopy in children is age dependent. Journal of Pediatric Surgery, 38(1), 105 - 110.
    • Vinardi S, Pierro A, Parkinson EJ, Vejchapipat P, Stefanutti G, Spitz L, Eaton S (2003). Hypothermia throughout intestinal ischaemia-reperfusion injury attenuates lung neutrophil infiltration. Journal of Pediatric Surgery, 38(1), 88 - 91.

    2002

    • (2002). Control of mitochondrial beta-oxidation flux. Progress in Lipid Research, 41, 197 - 239.
    • Donnell SC, Lloyd DA, Eaton S, Pierro A (2002). The metabolic response to intravenous medium-chain triglycerides in infants after surgery. The Journal of Pediatrics, 141(5), 689 - 694. doi:10.1067/mpd.2002.128889
    • (2002). Mitochondrial Fatty Acid beta-Oxidation in the Retinal Pigment Epithelium. PEDIATR RES, 52, 595 - 600.
    • (2002). Fatty acid oxidation in neonatal hepatocytes: Effects of sepsis and glutamine. Nutrition, 18(4), 298 - 300.
    • (2002). Hepatocyte mitochondrial metabolism is inhibited in neonatal rat endotoxaemia: effects of glutamine. Clinical Science, 102(3), 337 - 344.
    • Eaton S (2002). Long-chain acyl-CoA dehydrogenase deficiency, in National Association for Rare Disorders (eds) The NORD Guide to Rare Disorders. In Lippincott PA (Ed.), (pp. 4374 - ). : Williams & Wilkinspp.
    • (2002). Differential effects of neonatal endotoxemia on heart and kidney carnitine palmitoyl transferase I. Journal of Pediatric Surgery, 37(5), 723 - 726.
    • (2002). Hepatic glutamine metabolism during endotoxemia in neonatal rats. Nutrition, 18(4), 293 - 297.
    • Vejchapipat P, Eaton S, Fukumoto K, Parkes HG, Reynolds A, Spitz L, Pierro A (2002). Metabolic derangement during endotoxemia in neonatal rats.. , 10, 1919 - 1919.
    • Eaton S (2002). Very long-chain acyl-CoA dehydrogenase deficiency, in National Association for Rare Disorders (eds): The NORD Guide to Rare Disorders. In Lippincott PA (Ed.), (pp. 439 - 440). : Wlliamns & Wilkinspp.

    2001

    • Babu R, Eaton S, Drake DP, Spitz L, Pierro A (2001). Glutamine and glutathione counteract the inhibitory effects of mediators of sepsis in neonatal hepatocytes. Journal of Pediatric Surgery, 36(2), 282 - 286.
    • (2001). Endotoxaemia inhibits muscle-carnitine palmitoyl transferase I in suckling hea. Journal of Molecular and Cellular Cardiology, 33(6), A167 - A167.
    • (2001). Carnitine palmitoyl transferase I and the control of myocardial beta-oxidation flux. Biochemical Society Transactions, 29, 245 - 250.
    • New KJ, Eaton S, Elliott KRF, Spitz L, Quant PA (2001). Effect of lipopolysaccharide and cytokines on oxidative metabolism in neonatal rat hepatocytes. Journal of Pediatric Surgery, 36(2), 338 - 340.
    • Ververidis M, Kiely EM, Spitz L, Drake DP, Eaton S, Pierro A (2001). The clinical significance of thrombocytopenia in neonates with necrotizing enterocolitis. Journal of Pediatric Surgery, 36(5), 799 - 803.
    • Clayton PT, Eaton SJ, Aynsley-Green A, Edginton M, Hussain K, Krywawych S, Datta V, Malingre HE, Berger R, van den Berg IE (2001). Hyperinsulinism in short-chain L-3-hydroxyacyl-CoA dehydrogenase deficiency reveals the importance of beta-oxidation in insulin secretion. Journal of Clinical Investigation, 108(3), 457 - 465. doi:10.1172/JCI200111294
    • Clayton PT, Eaton S, Aynsley-Green A, Edginton M, Hussain K, Krywawych S, Datta V, Malingre HE, Berger R, van den Berg IE (2001). Hyperinsulinism in short-chain L-3-hydroxyacyl-CoA dehydrogenase deficiency reveals the importance of beta-oxidation in insulin secretion.. J Clin Invest, 108(3), 457 - 465. doi:10.1172/JCI11294
    • Eaton S, Bartlett K, Quant PA (2001). Carnitine palmitoyl transferase I and the control of beta-oxidation in heart mitochondria. Biochemical and Biophysical Research Communications, 285(2), 537 - 539.
    • Turi RA, Petros AJ, Eaton S, Fasoli L, Powis M, Basu R, Spitz L, Pierro A (2001). Energy metabolism of infants and children with systemic inflammatory response syndrome and sepsis. Annals of Surgery, 233(4), 581 - 587. doi:10.1097/00000658-200104000-00015

    2000

    • Markley MA, Eaton S, Pierro A (2000). Hepatocyte mitochondrial metabolism in neonatal sepsis is restored by glutamine. Proceedings of the Nutrition Society, 59, 153A - 153A.
    • Eaton S, Skinner R, Hale JP, Pourfarzam M, Roberts A, Price L, Bartlett K (2000). Plasma coenzyme Q(10) in children and adolescents undergoing doxorubicin therapy.. Clin Chim Acta, 302(1-2), 1 - 9.
    • Basu R, Muller DPR, Drury J, Cooke RW, Eaton S, Pierro A (2000). Intravenous medium-chain triacylglycerol administration is associated with increased free radical activity. Proceedings of the Nutrition Society, 59, 165A - 165A.
    • Romeo C, Eaton S, Spitz L, Pierro A (2000). Nitric oxide inhibits neonatal hepatocyte oxidative metabolism. Journal of Pediatric Surgery, 35(1), 44 - 48.
    • Romeo C, Eaton S, Spitz L, Pierro A (2000). Effect of nitric oxide on neonatal hepatocyte oxidative metabolism. Proceedings of the Nutrition Society, 59, 158A - 158A.
    • Eaton S, Skinner R, Hale JP, Pourfarzam M, Roberts A, Price L, Bartlett K (2000). Plasma coenzyme Q(10) in children and adolescents undergoing doxorubicin therapy. Clinica Chimica Acta, 302(1-2), 1 - 9.
    • Zamparelli M, Eaton S, Spitz L, Pierro A (2000). Amino acids counteract the inhibitory effect of fentanyl on hepatocyte oxidative metabolism. Journal of Pediatric Surgery, 35(5), 736 - 739.
    • Markley MA, Eaton S, Pierro A (2000). Neonatal hepatic oxidative metabolism following endotoxaemia. Proceedings of the Nutrition Society, 59, 162A - 162A.
    • Eaton S, Bursby T, Middleton B, Pourfarzam M, Mills K, Johnson AW, Bartlett K (2000). The mitochondrial trifunctional protein: centre of a beta-oxidation metabolon?. Biochemical Society Transactions, 28(Pt2), 177 - 182.

    1999

    • Basu R, Muller DPR, Papp E, Merryweather I, Eaton S, Klein N, Pierro A (1999). Free radical formation in infants: The effect of critical illness, parenteral nutrition, and enteral feeding. Journal of Pediatric Surgery, 34, 1091 - 1095.
    • New KJ, Eaton S, Elliott KR, Quant PA (1999). Is it time to reconsider the role of CPT I in control of hepatic ketogenesis?. Adv Exp Med Biol, 466, 227 - 232.
    • Eaton S, Bartlett K, Pourfarzam M, Markley MA, New KJ, Quant PA (1999). Production and export of acylcarnitine esters by neonatal rat hepatocytes.. Adv Exp Med Biol, 466, 155 - 159.
    • Eaton S, Middleton B, Sherratt HS, Pourfarzam M, Quant PA, Bartlett K (1999). Control of mitochondrial beta-oxidation at the levels of [NAD+]/[NADH] and CoA acylation.. Adv Exp Med Biol, 466, 145 - 154.
    • Romeo C, Eaton S, Quant PA, Spitz L, Pierro A (1999). Neonatal oxidative liver metabolism: Effects of hydrogen peroxide, a putative mediator of septic damage. Journal of Pediatric Surgery, 34, 1107 - 1111.
    • Eaton S, Bartlett K, Pourfarzam M (1999). Intermediates of myocardial mitochondrial beta-oxidation: possible channelling of NADH and of CoA esters. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1437(3), 402 - 408.
    • Zamparelli M, Eaton S, Quant PA, McEwan A, Spitz L, Pierro A (1999). Analgesic doses of fentanyl impair oxidative metabolism of neonatal hepatocytes.. J Pediatr Surg, 34(2), 260 - 263.
    • Eaton S, Bartlett K (1999). Tissue specific differences in intramitochondrial control of beta-oxidation.. Adv Exp Med Biol, 466, 161 - 168.
    • Basu R, Muller DP, Eaton S, Merryweather I, Pierro A (1999). Lipid peroxidation can be reduced in infants on total parenteral nutrition by promoting fat utilisation. Journal of Pediatric Surgery, 34(2), 255 - 259.

    1998

    • Quant PA, Lascelles CV, New KJ, Patil KK, Azzouzi N, Eaton S, Elliott KR (1998). Impaired neonatal hepatic ketogenesis.. Biochem Soc Trans, 26(2), 125 - 130.
    • Eaton S, Pourfarzam M, Bartlett K, Quant PA (1998). Beta-oxidation in neonatal cardiac mitochondria.. Biochem Soc Trans, 26(2), S91 - .
    • Eaton S, Middleton B, Bartlett K (1998). Control of mitochondrial β-oxidation: sensitivity of the trifunctional protein to [NAD+]/[NADH] and [acetyl-CoA]/[CoA]. Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1429(1), 230 - 238. doi:10.1016/S0167-4838(98)00246-5

    • Hall NJ, Eaton S, Peters MJ, Hiorns M, Alexander N, Azzopardi D, Edwards AD, Pierro A (). Moderate Controlled Hypothermia in Neonates with Advanced Necrotising Enterocolitis: Feasibility and Safety Study. Pediatrics, , - .