Prof Carol Dezateux

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Personal Profile

Name: Carol Dezateux Email: c.dezateux@ucl.ac.uk
Title: Prof Tel: 0044 207 905 2114
Department: ICH Pop, Policy & Practice Prog Fax:
Position: Professor of Paediatric Epidemiology Address: Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, London, WC1N 1EH
Research Domain: Ageing, Human Wellbeing, Infection, Immunology & Inflammation, Personalised Medicine, Populations & Lifelong Health, Reproduction & Development Web Page: Personal Web Page

Profile

Research Description

Carol’s research addresses early life influences on child health and the effectiveness of screening and other clinical and public health strategies to improve the health of children, based on prospective large scale population and patient cohort studies. She has led multicentre and multidisciplinary research initiatives to enhance the biomedical information collected in large scale population based studies such as the UK Millennium Cohort Study. These include objective measurements of body size and composition, physical activity, as well as exposure to infections and environmental pollutants, throughout early childhood, and the enhancement of this information through linkage to electronic health and other records. She was recently appointed as scientific leader of Life Study a new interdisciplinary UK birth cohort study which will chart the early lives of over 80,000 babies and their parents across the UK as a joint strategic research initiative of the ESRC and the MRC.

Carol has an international reputation for her work to evaluate the prevention effectiveness of newborn screening programmes for inherited or congenital disorders with life threatening or life limiting outcomes in later life. She was the principal investigator of a UK-wide collaborative study to evaluate newborn screening for a rare metabolic disorder associated with sudden infant death, which led to its implementation across the UK.  Her current research includes studies to examine the relation of newborn hip development to hip dysplasia in adult life.

Carol was a member of MRC Strategy Board (2007-11), the OSCHR Electronic  Health Records Research Board (2007-10), MRC Council (2004-7) and the Wellcome Trust Populations and Public Health funding committee (2004-7). She chaired the MRC Training and Careers Group (2007-11) and the MRC Training and Careers Development Board (2004-7). She was a member of the British Paediatric  Surveillance Unit Executive Committee (2002-13), the MRC Ethics Regulation and Public Involvement Committee (2004-13) and the Economic and Social Research Council [ESRC] Scientific Advisory Committee for the  Birth Cohort Studies (2005-12). She represented the Academy of Medical Sciences on the National Information Governance Board (NIGB) and the NIGB Ethics and Confidentiality Committee (2008-11). She served on the Academy of Medical Sciences Working Group, chaired by Professor Sir Michael Rawlins, which reviewed the regulation and governance of UK health research involving human participants, their tissue or their data (2011). She was elected as a member of the Council of the Academy of Medical Sciences in 2012.


Research Activities

Congenital Adrenal Hyperplasia Surveillance Study

Functional Data Analysis to analyse accelerometer data

Paediatric Epidemiology

Public Health and Epidemiology

The Bergen Hip Cohort Study (BHCS)

UK Collaborative Study of Congenital Heart Defects

UK Collaborative Study of Congenital Hypothyroidism

UK Collaborative Study of Newborn Screening for MCADD

Education Description

UCL Collaborators

Dr Leah Li; Dr Lena Ciric; Dr Anne Peasey; Prof Catherine Law; Prof Christine Power; Dr Mario Cortina Borja; Miss Juliet Oerton; Prof Peter Hindmarsh; Dr Rachel Knowles; Prof Tim Cole; Mr Francesco Sera

External Collaborators

Dr Timothy Cheetham; Dr Catherine Bull; Professor Gary Butler; Mr Paul Griffiths; Dr Christopher Wren; Prof Christopher Kelnar

Publications

    2014

    • Knowles RL, Dezateux C (2014). About Life Study: participant information for fathers and partners (version 2.0; dated 21.03.2014).
    • Knowles RL, Day T, Wade A, Bull C, Wren C, Dezateux C (2014). Patient-reported quality of life outcomes for children with serious congenital heart defects.. Archives of Disease in Childhood, , - . doi:10.1136/archdischild-2013-305130
    • Knowles RL, Dezateux C (2014). About Life Study: participant information for mothers with babies (version 2.0; dated 21.03.2014).
    • Leal J, Wordsworth S, Oerton J, Khalid JM, Dezateux C, UK Collaborative Study of Newborn Screening for MCADD (2014). Synthesis framework estimating prevalence of MCADD and sensitivity of newborn screening programme in the absence of direct evidence.. J Clin Epidemiol, , - . doi:10.1016/j.jclinepi.2014.05.011
    • Knowles RL, Dezateux C (2014). The Life Study Journey.
    • Rich C, Geraci M, Griffiths LJ, Sera F, Dezateux C, Cortina-Borja M (2014). Quality Control Methods in Accelerometer Data Processing: Identifying Extreme Counts. PLoS One, 9(1), e85134 - . doi:10.1371/journal.pone.0085134
    • Knowles RL, Dezateux C (2014). About Life Study: participant information for pregnant women (version 2.0; dated 21.03.2014).

    2013

    • Griffiths LJ, Cortina-Borja M, Sera F, Pouliou T, Geraci M, Rich C, Cole TJ, Law C, Joshi H, Ness AR, Jebb SA, Dezateux C (2013). How active are our children? Findings from the Millennium Cohort Study.. BMJ Open, 3(8), e002893 - . doi:10.1136/bmjopen-2013-002893
    • Rich C, Geraci M, Griffiths LJ, Sera F, Dezateux C, Cortina-Borja M (2013). Quality control methods in accelerometer data processing: Defining minimum wear time. PLoS ONE, 8(6), e67206 - . doi:10.1371/journal.pone.0067206
    • Knowles RL, Khalid JM, Oerton JM, Hindmarsh PC, Kelnar CJ, Dezateux C (2013). Late clinical presentation of congenital adrenal hyperplasia in older children: findings from national paediatric surveillance.. Arch Dis Child, , - . doi:10.1136/archdischild-2012-303070
    • Leal J, Ades A, Wordsworth S, Dezateux C (2013). Regional differences in the frequency of the c.985A>G ACADM mutation: findings from a meta-regression of genotyping and screening studies.. Clin Genet, , - . doi:10.1111/cge.12157
    • Rich C, Cortina-Borja M, Dezateux C, Geraci M, Sera F, Calderwood L, Joshi H, Griffiths LJ (2013). Predictors of non-response in a UK-wide cohort study of children's accelerometer-determined physical activity using postal methods. BMJ Open, 3(3), - . doi:10.1136/bmjopen-2012-002290
    • Laborie LB, Engesæter IØ, Lehmann TG, Sera F, Dezateux C, Engesæter LB, Rosendahl K (2013). Radiographic measurements of hip dysplasia at skeletal maturity--new reference intervals based on 2,038 19-year-old Norwegians.. Skeletal Radiol, 42(7), 925 - 935. doi:10.1007/s00256-013-1574-y

    2012

    • Griffiths LJ, Rich C, Dezateux C (2012). Seasonal variation in accelerometer-determined sedentary behaviour and physical activity in children: a review.. Int J Behav Nutr Phys Act., 9(1), 49 - .
    • Knowles RL, Bull C, Wren C, Dezateux C (2012). Mortality with congenital heart defects in England and Wales, 1959-2009: exploring technological change through period and birth cohort analysis.. Arch Dis Child, 97(10), 861 - 865. doi:10.1136/archdischild-2012-301662
    • Cooper C, Frank J, Leyland A, Hardy R, Lawlor DA, Wareham NJ, Dezateux C, Inskip H (2012). Using cohort studies in lifecourse epidemiology.. Public Health, 126(3), 190 - 192. doi:10.1016/j.puhe.2011.12.002
    • Khalid JM, Oerton JM, Dezateux C, Hindmarsh PC, Kelnar CJ, Knowles RL (2012). Incidence and clinical features of congenital adrenal hyperplasia in Great Britain.. Arch Dis Child, 97(2), 101 - 106. doi:10.1136/archdischild-2011-300234
    • Geraci M, Rich C, Sera F, Cortina-Borja M, Griffiths LJ, Dezateux C (2012). Technical report on accelerometry data processing in the Millennium Cohort Study.

    2011

    • Griffiths LJ, Dezateux C, Cole TJ (2011). Sex and ethnic differences in the waist circumference of 5-year-old children: findings from the Millennium Cohort Study.. Int J Pediatr Obes, 6(2-2), e196 - e198. doi:10.3109/17477166.2010.526224
    • Bruras KR, Aukland SM, Markestad T, Sera F, Dezateux C, Rosendahl K (2011). Newborns With Sonographically Dysplastic and Potentially Unstable Hips: 6-Year Follow-up of an RCT. PEDIATRICS, 127(3), E661 - E666. doi:10.1542/peds.2010-2572
    • Oerton J, Khalid JM, Besley G, Dalton RN, Downing M, Green A, Henderson M, Krywawych S, Leonard J, Andresen BS, Dezateux C (2011). Newborn screening for medium chain acyl-CoA dehydrogenase deficiency in England: prevalence, predictive value and test validity based on 1.5 million screened babies.. J Med Screen, 18(4), 173 - 181. doi:10.1258/jms.2011.011086
    • Pulsford RM, Cortina-Borja M, Rich C, Kinnafick FE, Dezateux C, Griffiths LJ (2011). Actigraph accelerometer-defined boundaries for sedentary behaviour and physical activity intensities in 7 year old children.. PLoS One, 6(8), e21822 - . doi:10.1371/journal.pone.0021822
    • Griffiths LJ, Dezateux C, Hill A (2011). Is obesity associated with emotional and behavioural problems in children? Findings from the Millennium Cohort Study.. Int J Pediatr Obes, 6(2-2), e423 - e432. doi:10.3109/17477166.2010.526221
    • Knowles RL, Bull C, Wren C, Dezateux C (2011). Ethics, governance and consent in the UK: implications for research into the longer-term outcomes of congenital heart defects.. Arch Dis Child, 96(1), 14 - 20. doi:10.1136/adc.2008.152975

    2010

    • Rosendahl K, Dezateux C, Fosse KR, Aase H, Aukland SM, Reigstad H, Alsaker T, Moster D, Lie RT, Markestad T (2010). Immediate treatment versus sonographic surveillance for mild hip dysplasia in newborns.. Pediatrics, 125(1), e9 - 16. doi:10.1542/peds.2009-0357
    • Griffiths LJ, Hawkins SS, Cole TJ, Dezateux C, Millennium Cohort Study Child Health Group (2010). Risk factors for rapid weight gain in preschool children: findings from a UK-wide prospective study.. Int J Obes (Lond), 34(4), 624 - 632. doi:10.1038/ijo.2010.10
    • Griffiths LJ, Dowda M, Dezateux C, Pate R (2010). Associations between sport and screen-entertainment with mental health problems in 5-year-old children.. Int J Behav Nutr Phys Act, 7, 30 - . doi:10.1186/1479-5868-7-30
    • Khalid JM, Oerton J, Besley G, Dalton N, Downing M, Green A, Henderson M, Krywawych S, Wiley V, Wilcken B, Dezateux C, UK Collaborative Study of Newborn Screening for MCADD (2010). Relationship of octanoylcarnitine concentrations to age at sampling in unaffected newborns screened for medium-chain acyl-CoA dehydrogenase deficiency.. Clin Chem, 56(6), 1015 - 1021. doi:10.1373/clinchem.2010.143891
    • Manikkavasagan G, Dezateux C, Wade A, Bedford H (2010). The epidemiology of chickenpox in UK 5-year olds: an analysis to inform vaccine policy.. Vaccine, 28(48), 7699 - 7705. doi:10.1016/j.vaccine.2010.09.017

    2009

    • Hardelid P, Cortina-Borja M, Williams D, Tookey PA, Peckham CS, Cubitt WD, Dezateux C (2009). Rubella seroprevalence in pregnant women in North Thames: estimates based on newborn screening samples. Journal of Medical Screening, 16(1), 1 - 6.
    • Bartington SE, Peckham C, Brown D, Joshi H, Dezateux C, Millennium Cohort Study Child Health Group (2009). Feasibility of collecting oral fluid samples in the home setting to determine seroprevalence of infections in a large-scale cohort of preschool-aged children.. Epidemiol Infect, 137(2), 211 - 218. doi:10.1017/S0950268808000927
    • Hawkins SS, Pearce A, Cole TJ, Law C, Millennium Cohort Study Child Health Group , Dezateux C, Peckham C, Bedford H, Rahi J, Griffiths LJ, Cumberland P, Bartington S (2009). Perceived and objective measures of the neighbourhood environment and overweight in preschool children and their mothers.. Int J Pediatr Obes, 4(3), 183 - 192. doi:10.1080/17477160802596155
    • Leonard JV, Dezateux C (2009). Newborn screening for medium chain acyl CoA dehydrogenase deficiency. Archives of Disease in Childhood, 94(3), 235 - 238.
    • Griffiths LJ, Smeeth L, Hawkins SS, Cole TJ, Dezateux C (2009). Effects of infant feeding practice on weight gain from birth to 3 years. Archives of Disease in Childhood, 94(8), 577 - 582.

    2008

    • Hardelid P, Cortina-Borja M, Munro A, Jones H, Cleary M, Champion MP, Foo Y, Scriver CH, Dezateux C (2008). The birth prevalence of PKU in populations of European, South Asian and sub-Saharan African ancestry living in South East England. Annals of Human Genetics, 72, - .
    • Hardelid P, Williams D, Dezateux C, Tookey PA, Peckham CS, Cubitt WD, Cortina-Borja M (2008). Analysis of rubella antibody distribution from newborn dried blood spots using finite mixture models.. Epidemiol Infect, 136(12), 1698 - 1706. doi:10.1017/S0950268808000393
    • Khalid JM, Oerton J, Cortina-Borja M, Andresen BS, Besley G, Dalton RN, Downing M, Green A, Henderson M, Leonard J, Dezateux C, UK Collaborative Study Newborn Scr (2008). Ethnicity of children with homozygous c.985A > G medium-chain acyl-CoA dehydrogenase deficiency: findings from screening approximately 1.1 million newborn infants. J MED SCREEN, 15(3), 112 - 117. doi:10.1258/jms.2008.008043
    • Hawkins SS, Griffiths LJ, Cole TJ, Dezateux C, Law C, Millennium Cohort Study Child Health Group (2008). Regional differences in overweight: an effect of people or place?. Arch Dis Child, 93(5), 407 - 413. doi:10.1136/adc.2007.128231
    • Hardelid P, Williams D, Dezateux C, Cubitt WD, Peckham CS, Tookey PA, Cortina-Borja M (2008). Agreement of rubella IgG antibody measured in serum and dried blood spots using two commercial enzyme-linked immunosorbent assays. Journal of Medical Virology, 80(2), 360 - 364.

    2007

    • Griffiths LJ, Tate AR, Dezateux C, Millennium Cohort Study Child Health Group (2007). Do early infant feeding practices vary by maternal ethnic group?. Public Health Nutr, 10(9), 957 - 964. doi:10.1017/S1368980007665513
    • Grosse SD, Dezateux C (2007). Newborn screening for inherited metabolic disease.. Lancet, 369(9555), 5 - 6. doi:10.1016/S0140-6736(07)60005-1
    • Dezateux C, Rosendahl K (2007). Developmental dysplasia of the hip.. Lancet, 369(9572), 1541 - 1552. doi:10.1016/S0140-6736(07)60710-7
    • Knowles RL, Griebsch I, Bull C, Brown J, Wren C, Dezateux C (2007). Quality of life and congenital heart defects: comparing parent and professional values.. Arch Dis Child, 92(5), 388 - 393. doi:10.1136/adc.2005.075606
    • Hawkins SS, Griffiths LJ, Dezateux C, Law C, Millennium Cohort Study Child Health Group (2007). The impact of maternal employment on breast-feeding duration in the UK Millennium Cohort Study.. Public Health Nutr, 10(9), 891 - 896. doi:10.1017/S1368980007226096
    • Khalid JM, Oerton J, Cortina-Borja M, Andresen BS, Besley G, Dalton N, Downing M, Foo Y, Green A, Henderson M, Dezateux C (2007). Ethnic-Specific Birth Prevalence of 985A>G Homozygous Medium-Chain Acyl-CoA Dehydrogenase Deficiency (MCADD): Results from Screening ~ 1.1 Million Newborn Infants.
    • Hardelid P, Williams D, Dezateux C, Peckham CS, Tookey PA, Cortina-Borja M (2007). Using continuous finite mixture models to estimate rubella susceptibility among pregnant women in North Thames.
    • Hardelid P, Williams D, Cubbit WD, Peckham CS, Tookey PA, Cortina-Borja M, Dezateux C (2007). The Seroprevalence of Rubella in pregnant women in North Thames..
    • Cortina-Borja M, Tookey PA, Williams D, Hardelid P, Cubbit WD, Peckham CS, Dezateux C (2007). Using data linkage from unlinked anonymous surveillance of neonatal dried blood spots.
    • Griebsch I, Knowles R, Brown J, Bull C, Wren C, Dezateux C (2007). Comparing the clinical and economic effects of clinical examination, pulse oximetry, and echocardiography in newborn screening for congential heart defects: A probablistic cost-effectiveness model and value of information analysis. International Journal of Technology Assessment in Health Care, 23(2), 192 - 204. doi:10.1017/S0266462307070304
    • Higgins PT, Little J, Ioannidis JPA, Bray MS, Manolio TA, Smeeth L, Sterne JA, Anagnostelis B, Butterworth AS, Danesh J, Dezateux C (2007). Turning the Pump Handle: Evolving Methods for Intergrating the Evidence on Gene-Disease Association. American Journal of Epidemiology, , - .
    • Hawkins SS, Griffiths LJ, Dezateux C, Law C, Millennium Cohort Study Child Health Group (2007). Maternal employment and breast-feeding initiation: findings from the Millennium Cohort Study.. Paediatr Perinat Epidemiol, 21(3), 242 - 247. doi:10.1111/j.1365-3016.2007.00812.x

    2006

    • Bartington S, Griffiths LJ, Tate AR, Dezateux C, Millennium Cohort Study Health Group (2006). Are breastfeeding rates higher among mothers delivering in Baby Friendly accredited maternity units in the UK?. Int J Epidemiol, 35(5), 1178 - 1186. doi:10.1093/ije/dyl155
    • Leonard JV, Shortland G, Zschocke J, Pourfarzam M, Calvin J, Downing M, Green A, Oerton J, Andresen BS, Olpin S, Dezateux C (2006). Consensus case definitions for MCADD among infants with presumptive positive newborn screening results. Journal of Inherited Metabolic Disease, 29, 19 - 19.
    • Samad L, Tate AR, Dezateux C, Peckham C, Butler N, Bedford H (2006). Differences in risk factors for partial and no immunisation in the first year of life: prospective cohort study.. BMJ, 332(7553), 1312 - 1313. doi:10.1136/bmj.332.7553.1312
    • Griffiths LJ, Dezateux C, Cole TJ (2006). Differential parental weight and height contributions to offspring birthweight and weight gain in infancy. Int J Epidemiol, , - .
    • Knowles RL, Smith A, Lynn R, Preece M, Cameron JC, Pebody R, Dezateux C (2006). What is the contribution of notification by specialists to the ascertainment of rare childhood conditions through the British Paediatric Surveillance Unit?.
    • Gilbert R, Dezateux C (2006). Newborn screening for congenital toxoplasmosis: feasible, but benefits are not established. Archives of Disease in Childhood, 91(8), 629 - 631. doi:10.1136/adc.2006.094870
    • Walton S, Bedford HE, Dezateux C (2006). Use of personal child health records in the UK: findings from the millennium cohort study. BMJ (Clinical Research Ed.), 332(7536), 269 - 270. doi:10.1136/bmj.332.7536.269
    • Tate AR, Dezateux C, Cole TJ (2006). Is infant growth changing?. International Journal of Obesity, 30(7), 1094 - 1096.
    • Knowles RL, Smith A, Lynn R, Cameron JC, Pebody R, Dezateux C (2006). NP.

    2005

    • Griffiths LJ, Tate AR, Dezateux C (2005). The contribution of parental and community ethnicity to breastfeeding practices: evidence from the Millennium Cohort Study.. Int J Epidemiol, 34(6), 1378 - 1386. doi:10.1093/ije/dyi162
    • Tate AR, Calderwood L, Dezateux C, Joshi H (2005). Mother's consent to linkage of survey data with her child's birth records in a multi-ethnic national cohort study. INT J EPIDEMIOL, , - .
    • Gray A, Elbourne D, Dezateux C, King A, Quinn A, Gardner F (2005). Economic evaluation of ultrasonography in the diagnosis and management of developmental hip dysplasia in the United Kingdom and Ireland. J BONE JOINT SURG AM, 87(11), 2472 - 2479.
    • Dezateux C, Roposch A (2005). The puzzles of Perthes' disease: definitive studies of causal factors are needed. J Bone Joint Surg Br, 87(11), 1463 - 1464.
    • Wright CM, Waterston AJ, Cole TJ, Dezateux CA (2005). True status of supplement not made clear to reader. Archives of Disease in Childhood, 90(10), 1098 - .
    • Hardelid P, Dezateux C (2005). Neonatal screening for inborn errors of metabolism. The Lancet, 365(9478), 2176 - .
    • Tate AR, Dezateux C, Cole TJ, Davidson L, MCS CHG (2005). Factors affecting a mother's recall of her baby's birth weight. International Journal of Epidemiology, 34(3), 688 - 695. doi:10.1093/ije/dyi029
    • Bartington SE, Foster LJ, Tate AR, Dezateux C (2005). Evaluation of the UNICEF UK Baby Friendly Initiative for the promotion of breastfeeding: findings from the Millennium Cohort Study. Archives of Disease in Childhood, , - .
    • Dezateux C, Foster L, Tate R, Walton S, Samad L, Bedford H, Bartington S, Peckham C, Cole TJ, Butler N (2005). Children's health. In Dex S, Joshi H (Ed.), Children of the 21st century: from birth to 9 months (pp. 133 - 158). : Policy Press.
    • Downing M, Andresen BS, Bonham J, Dezateux C, Manning NJ, Olpin SE, on BOTLSWGOTUKCSONSFMCADD (2005). Newborn Screening for Medium Chain Acyl CoA Dehydrogenase Deficiency: acylcarnitine C8/C10 ratio at day 6 differentiates affected cases from carriers.
    • Elbourne D, Dezateux C (2005). Hip dysplasia and ultrasound imaging of whole populations: the precautionary principle revisited. ARCH DIS CHILD FETAL NEONATAL ED, 90(1), F2 - F3.
    • Gardner F, Dezateux C, Elbourne D, Gray A, King A, Quinn A (2005). The hip trial: psychosocial consequences for mothers of using ultrasound to manage infants with developmental hip dysplasia. Archives of Disease in Childhood, 90(1), F17 - F24.
    • Goddard P, Hardy D, Hutchin T, Phillips P, Dezateux C, Green A, on BOTCSWGOTUKCSONSFMCADD (2005). Quality Assuring a Multicentre Newborn Screening Programme for MCADD in the UK.
    • Kirkpatrick S, Oerton J, Fitzpatrick R, Dezateux C, on BOTUKCSONSFMCADDUKCSNSMCADD (2005). Parental Responses to a Newborn Screening Diagnosis of Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCADD).
    • Knowles R, Griebsch I, Dezateux C, Brown J, Bull C, Wren C (2005). Newborn screening for congenital heart defects: a systematic review and cost-effectiveness analysis. HEALTH TECHNOLOGY ASSESSMENT, 9(44), 1 - +.
    • Oerton J, Downing M, Andresen BS, Champion M, Cleary M, Chakrapani A, Sharrard M, Walter J, Phillips P, Dezateux C, on BOTCSWGOTUKCSONSFMCADD (2005). Predictive value, clinical status and genotype of Medium Chain Acyl CoA Dehydrogenase Deficiency (MCADD) ascertained by screening at one week of age using electrospray tandem mass spectrometry of underivatised blood spots: findings from a UK multicentre s.
    • Oliver S, Dezateux C, Kavanagh J, Lempert T, Stewart R (2005). Disclosing to parents newborn carrier status identified by routine blood spot screening. COCHRANE DATABASE SYST REV, (4), CD003859 - .
    • Phillips P, Dalton N, Besley G, Bonham J, Foo Y, Green A, Henderson M, Oerton J, Dezateux C, on BOTLSWGOTUKCSONSFMCADD (2005). Newborn screening for Medium Chain Acyl CoA Dehydrogenase Deficiency at one week of age: octanoyl carnitine distributions from a multicentre study using electrospray tandem mass spectrometry of underivatised blood spot samples.
    • Samad L, Bedford H, Tate AR, Dezateux C, Peckham C, Butler N (2005). Immunisation uptake among infants in the UK: findings from the Millennium Cohort Study.
    • Walton S, Bedford H, Dezateux C (2005). Use of Personal Child Health Records: findings from the Millennium Cohort Study.

    2004

    • Oliver S, Dezateux C, Kavanagh J, Lempert T, Stewart R (2004). Disclosing to parents newborn carrier status identified by routine blood spot screening.
    • Hoo AF, Stocks J, Lum S, Wade AM, Castle RA, Costeloe KL, Dezateux C (2004). Development of lung function in early life: influence of birth weight in infants of nonsmokers. American Journal of Respiratory and Critical Care Medicine, 170(5), 527 - 533. doi:10.1164/rccm.200311-1552OC
    • Ranganathan SC, Stocks J, Dezateux C, Bush A, Wade A, Carr S, Castle R, Dinwiddie R, Hoo AF, Lum S, Price J, Stroobant J, Wallis C (2004). The evolution of airway function in early childhood following clinical diagnosis of cystic fibrosis. American Journal of Respiratory and Critical Care Medicine, 169(8), 928 - 933. doi:10.1164/rccm.200309-1344OC
    • Dezateux CA, Lum S, Hoo AF, Hawdon J, Costeloe K, Stocks J (2004). Low birth weight for gestation and airway function in infancy: exploring the fetal origins hypothesis. Thorax, 59(1), 60 - 66.

    2003

    • Dezateux C (2003). Newborn screening for medium chain acyl-CoA dehydrogenase deficiency: evaluating the effects on outcome. European Journal of Pediatrics, 162(Supple), S25 - S28.
    • Brown J, Dezateux C, Karnon J, Parnaby A, Arthur R (2003). Efficiency of alternative policy options for screening for developmental dysplasia of the hip in the United Kingdom. Archives of Disease in Childhood, 88(9), 760 - 766.
    • Stocks J, Dezateux C (2003). The effect of parental smoking on lung function and development during infancy. Respirology, 8(3), 266 - 285.
    • Dezateux C, Brown J, Arthur R, Karnon J, Parnaby A (2003). Performance, treatment pathways, and effects of alternative policy options for screening for developmental dysplasia of the hip in the United Kingdom.. Arch Dis Child, 88(9), 753 - 759.
    • Hoo AF, Stocks J, Cole TJ, Dezateux C (2003). Prediction of maximum flow at functional residual capacity in infants: normal range. American Journal of Respiratory and Critical Care Medicine, 168, 130 - .

    2002

    • Rahi JS, Dezateux C (2002). Improving the detection of childhood visual problems and eye disorders. The Lancet, 359(9312), 1083 - 1084.
    • Hoo AF, Dezateux C, Hanrahan JP, Cole TJ, Tepper RS, Stocks J (2002). Sex-Specific Prediction Equations for maxFRC in Infancy: A Multicenter Collaborative Study. American Journal of Respiratory and Critical Care Medicine, 165(8), 1084 - 1092.
    • Elliman DAC, Dezateux C, Bedford HE (2002). Newborn and childhood screening programmes: criteria, evidence, and current policy. Archives of Disease in Childhood, 87, 6 - 9.
    • (2002). Ultrasonography in the diagnosis and management of developmental hip dysplasia (UK Hip Trial): clinical and economic results of a multicentre randomised controlled trial. The Lancet, 360(9350), 2009 - 2017. doi:10.1016/S0140-6736(02)12024-1
    • (2002). Development of airway function in infancy after preterm delivery. The Journal of Pediatrics, 141(5), 652 - 658.
    • Ranganathan S, Bush A, Dezateux CA, Carr SB, Hoo AF, Lum S, Madge SL, Price J, Stroobant J, Wade A, Wallis C, Wyatt H, Stocks J (2002). Relative ability of full and partial forced expiratory maneuvers to identify diminished airway function in infants with cystic fibrosis. American Journal of Respiratory and Critical Care Medicine, 166(10), 1350 - 1357. doi:10.1164/rccm.2202041
    • (2002). Screening for inherited metabolic disease in newborn infants using tandem mass spectrometry. BMJ (Clinical Research Ed.), 324(7328), 4 - 5.
    • Ranganathan S, Dezateux CA, Goetz I, Hoo AF, Wade A, Stocks J (2002). A longitudinal study of airway function in infants newly diagnosed with cystic fibrosis. On behalf of the London Collaborative Cystic Fibrosis Study Group.
    • Dezateux C, Hoo AF, Cole TJ, Stocks J, Hanrahan J (2002). Influence of maternal smoking on peripheral airway function during the first 18 months of life.
    • Hoo AF, Dezateux CA, Henschen M, Costeloe K, Stocks J (2002). Airway function is diminished at 1 year in 'healthy' infants delievered prematurely.
    • Ranganathan S, Bush A, Dezateux CA, Wade A, Goetz I, Hoo AF, Lum S, Stocks J (2002). Diminished airway function in newly diagnosed infants with cystic fibrosis persists when measured longitudinally.

    2001

    • Merelle ME, Nagelkerke AF, Lees CM, Dezateux C (2001). Newborn screening for cystic fibrosis.. Cochrane Database Syst Rev, (3), CD001402 - . doi:10.1002/14651858.CD001402
    • Rahi JS, Dezateux C (2001). Epidemiology of childhood visual impairment in the United Kingdom and Ireland.. In (Ed.), Recent Advances in Paediatrics, Volume 19 (pp. 97 - 114). : Churchill Livingston.
    • Merelle ME, Nagelkerke AF, Lees CM, Dezateux C (2001). Newborn screening for cystic fibrosis (Cochrane Review). COCHRANE DATABASE SYST REV, 3, CD001402 - .
    • Hoo AF, Lum SY, Goetz I, Dezateux C, Stocks J (2001). Influence of jacket placement on respiratory compliance during raised lung volume measurements in infants. Pediatric Pulmonology, 31(1), 51 - 58.
    • Hoo AF, Henschen M, Dezateux CA, Costeloe K, Stocks J (2001). Growth of airway function in preterm infants.
    • Hoo AF, Lum S, Dezateux CA, Davies S, Costeloe K, Hawdon J, Stocks J (2001). Association of sex, birthweight and airway function in infancy.
    • Dezateux C (2001). Screening newborn infants for cystic fibrosis. J MED SCREEN, 8(2), 57 - 58.
    • Ranganathan SC, Dezateux C, Bush A, Carr SB, Castle RA, Madge S, Price J, Stroobant J, Wade A, Wallis C, Stocks J (2001). Airway function in infants newly diagnosed with cystic fibrosis. The Lancet, 358(9297), 1964 - 1965. doi:10.1016/S0140-6736(01)06970-7
    • Lum S, Hoo AF, Dezateux C, Goetz I, Wade A, DeRooy L, Costeloe K, Stocks J (2001). The association between birthweight, sex, and airway function in infants of nonsmoking mothers. AM J RESPIR CRIT CARE MED, 164(11), 2078 - 2084.
    • Sikorski J, Dezateux C (2001). Duration of breast feeding and adult arterial distensibility. Authors did not discuss data from prospective studies. BMJ (Clinical Research Ed.), 323(7314), 690 - 691.
    • Dezateux CA, Stocks J, Wade AM, Dundas I, Fletcher ME (2001). Airway function at one year: association with premorbid airway function, wheezing, and maternal smoking. Thorax, 56(9), 680 - 686. doi:10.1136/thorax.56.9.680
    • Rahi JS, Dezateaux C (2001). Measuring and interpreting the incidence of congenital ocular anomalies: lessons from a national study of congenital cataract in the UK. Investigative Ophthalmology and Visual Science, 42(7), 1444 - 1448.
    • Sikorski J, Boyd F, Dezateux C, Wade A, Rowe J (2001). Prevalence of breastfeeding at four months in general practices in south London. British Journal of General Practice, 51(467), 445 - 450.
    • Goetz I, Hoo AF, Lum S, Dezateux CA, Stocks J (2001). Differences in recoil pressure do not account for diminished peripheral airway function in SGA infants.
    • Hoo AF, Dezateux CA, Cole TJ, Hanrahan J, Tepper RS, Stocks J (2001). Sex-specific cross-sectional reference standards for V'maxFRC in infancy: a multicenter collaborative study.
    • Lum S, Hoo AF, Dezateux CA, Castle R, Costeloe K, Stocks J (2001). Effect of birthweight on airway function in infants.

    2000

    • Jones D, Dezateux CA, Danielsson LG, Paton RW, Clegg J (2000). At the crossroads - Neonatal detection of developmental dysplasia of the hip. JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, 82B(2), 160 - 164.
    • Dezateux C, Crighton A (2000). Oral non-steroidal anti-inflammatory drug therapy for cystic fibrosis.. Cochrane Database Syst Rev, (2), CD001505 - . doi:10.1002/14651858.CD001505
    • Merelle ME, Lees CM, Nagelkerke AF, Dezateux C (2000). Newborn screening for cystic fibrosis.. Cochrane Database Syst Rev, (2), CD001402 - . doi:10.1002/14651858.CD001402
    • Dezateux C, Walters S, Balfour-Lynn I (2000). Inhaled corticosteroids for cystic fibrosis.. Cochrane Database Syst Rev, (2), CD001915 - . doi:10.1002/14651858.CD001915
    • Lees CM, Davies S, Dezateux C (2000). Neonatal screening for sickle cell disease.. Cochrane Database Syst Rev, (2), CD001913 - . doi:10.1002/14651858.CD001913
    • Rahi JS, Dezateux C (2000). Congenital and infantile cataract in the United Kingdom: underlying or associated factors. British Congenital Cataract Interest Group.. Invest Ophthalmol Vis Sci, 41(8), 2108 - 2114.

    1999

    • (1999). Detection of congenital and infantile cataract in the United Kingdom: the role of childhood screening and surveillance. BMJ (Clinical Research Ed.), 318, 362 - 365.
    • Rahi JS, Dezateux C, for TBCCIG (1999). Capture-recapture analysis of ascertainment by active surveillance in the British Congenital Cataract Study. Investigative Ophthalmology and Visual Science, 40(1), 236 - 239.
    • Dezateux C, Stocks J, Dundas I, Fletcher ME (1999). Impaired airway function and wheezing in infancy: the influence of maternal smoking and a genetic predisposition to asthma. AM J RESPIR CRIT CARE MED, 159(2), 403 - 410.
    • Rahi JS, Dezateux C (1999). National cross sectional study of detection of congenital and infantile cataract in the United Kingdom: role of childhood screening and surveillance. The British Congenital Cataract Interest Group. BMJ (Clinical Research Ed.), 318(7180), 362 - 365.
    • Balfour-Lynn IM, Dezateux C (1999). Corticosteroids and ibuprofen in cystic fibrosis. Thorax, 54, 657 - .
    • Zeuner D, Ades AE, Karnon J, Brown J, Dezateux C, Anionwu EN (1999). Antenatal and neonatal haemoglobinopathy screening in the UK: review and economic analysis.. Health Technol Assess, 3(11), i - 186.

    1998

    • Dezateux C (1998). Evaluating newborn screening programmes based on dried blood spots: future challenges.. Br Med Bull, 54(4), 877 - 890.
    • Dezateux C, Peckham C (1998). Perinatal testing. Testing times for pregnant women.. Lancet, 352 Suppl 4, SIV24 - .
    • Rahi JS, Dezateux C (1998). Epidemiology of visual impairment in Britain.. Archives of Disease in Childhood, 78, 381 - 386.
    • Godward S, Dezateux C (1998). Surgery for congenital dislocation of the hip in the UK as a measure of outcome of screening. MRC Working Party on Congenital Dislocation of the Hip. Medical Research Council.. Lancet, 351(9110), 1149 - 1152.
    • Peckham CS, Dezateux C (1998). Issues underlying the evaluation of screening programmes.. Br Med Bull, 54(4), 767 - 778.
    • Elbourne D, Dezateux C (1998). Screening toddlers for iron deficiency anaemia in general practice. Effect of delaying timing of clamping of cord is being studied.. BMJ, 316(7125), 145 - 146.
    • Hoo AF, Henschen M, Dezateux C, Costeloe K, Stocks J (1998). Respiratory function among preterm infants whose mothers smoked during pregnancy.. Am J Respir Crit Care Med, 158(3), 700 - 705. doi:10.1164/ajrccm.158.3.9711057

    1997

    • Dezateux C, Delves HT, Stocks J, Wade A, Pilgrim L, Costeloe K (1997). Urinary antimony in infancy.. Arch Dis Child, 76(5), 432 - 436.
    • Dezateux C, Fletcher ME, Dundas I, Stocks J (1997). Infant respiratory function after RSV-proven bronchiolitis.. Am J Respir Crit Care Med, 155(4), 1349 - 1355. doi:10.1164/ajrccm.155.4.9105078
    • Dezateux C, Stocks J (1997). Lung development and early origins of childhood respiratory illness.. Br Med Bull, 53(1), 40 - 57.
    • Dezateux C (1997). Five female doctors should have been named in article. BMJ (Clinical Research Ed.), 314, 1199 - 1199.
    • Rahi J, Dezateux C (1997). The future of preschool vision screening services in Britain. BMJ (Clinical Research Ed.), 315, 1247 - 1248.
    • Stocks J, Henschen M, Hoo A, Costeloe K, Dezateux C (1997). Influence of ethnicity and gender on airway function in preterm infants. American Journal of Respiratory and Critical Care Medicine, 156, 1855 - 1862.
    • Dezateux C, Godward S (1997). Screening for congenital dislocation of the hip in the newborn and young infants. In David TJ (Ed.), Recent advances in paediatrics (pp. 41 - 57). : Churchill Livingstone.
    • Delves T, Sieniawska CE, Fell GS, Lyon TDB, Dezateux C, Cullen A, Variend S, Bonham JR, Chantler SM (1997). Determination of antimony in urine,blood and serum and in liver and lung tissues of infants by inductively coupled plasma mass spectrometry. Analyst, 122, 1323 - 1329.

    1996

    • Dezateux C, Godward S (1996). A national survey of screening for congenital dislocation of the hip.. Arch Dis Child, 74(5), 445 - 448.
    • Laird L, Dezateux C, Anionwu EN (1996). Neonatal screening for sickle cell disorders: what about the carrier infants?. BMJ, 313(7054), 407 - 411.
    • Godward S, Dezateux C (1996). Validation of the reporting bases of the orthopaedic and paediatric surveillance schemes.. Arch Dis Child, 75(3), 232 - 236.
    • Stocks J, Dezateux C, Hoo AF, Rabbette PS, Costeloe K, Wade A (1996). Delayed maturation of Hering-Breuer inflation reflex activity in preterm infants.. Am J Respir Crit Care Med, 154(5), 1411 - 1417. doi:10.1164/ajrccm.154.5.8912757

    1995

    • Jackson E, Stocks J, Pilgrim L, Dundas I, Dezateux C (1995). A critical assessment of uncalibrated respiratory inductance plethysmography (Respitrace) for the measurement of tidal breathing parameters in newborns and infants.. Pediatr Pulmonol, 20(2), 119 - 124.
    • Dezateux C, Godward S (1995). Evaluating the national screening programme for congenital dislocation of the hip.. J Med Screen, 2(4), 200 - 206.
    • Dundas I, Dezateux CA, Fletcher ME, Jackson EA, Stocks J (1995). Comparison of single-breath and plethysmographic measurements of resistance in infancy.. Am J Respir Crit Care Med, 151(5), 1451 - 1458. doi:10.1164/ajrccm.151.5.7735599

    1994

    • Dezateux C, Hey E (1994). Role of ultrasound in congenital hip dysplasia.. Arch Dis Child, 71(2), 180 - .
    • Stocks J, Dezateux CA, Jackson EA, Hoo AF, Costeloe KL, Wade AM (1994). Analysis of tidal breathing parameters in infancy: how variable is TPTEF:TE?. Am J Respir Crit Care Med, 150(5 Pt 1), 1347 - 1354. doi:10.1164/ajrccm.150.5.7952563
    • Rabbette PS, Fletcher ME, Dezateux CA, Soriano-Brucher H, Stocks J (1994). Hering-Breuer reflex and respiratory system compliance in the first year of life: a longitudinal study.. J Appl Physiol (1985), 76(2), 650 - 656.
    • Dezateux CA, Stocks J, Dundas I, Jackson EA, Fletcher ME (1994). The relationship between tPTEF:tE and specific airway conductance in infancy.. Pediatr Pulmonol, 18(5), 299 - 307.

    1993

    • Gappa M, Fletcher ME, Dezateux CA, Stocks J (1993). Comparison of nitrogen washout and plethysmographic measurements of lung volume in healthy infants.. Am Rev Respir Dis, 148(6 Pt 1), 1496 - 1501. doi:10.1164/ajrccm/148.6_Pt_1.1496

    1992

    • Fletcher ME, Dezateux CA, Stocks J (1992). Respiratory compliance in infants--a preliminary evaluation of the multiple interrupter technique.. Pediatr Pulmonol, 14(2), 118 - 125.

    1991

    • Jackson EA, Rabbette PS, Dezateux C, Hatch DJ, Stocks J (1991). The effect of triclofos sodium sedation on respiratory rate, oxygen saturation, and heart rate in infants and young children.. Pediatr Pulmonol, 10(1), 40 - 45.
    • Rabbette PS, Dezateux CA, Fletcher ME, Costeloe KL, Stocks J (1991). Influence of sedation on the Hering-Breuer inflation reflex in healthy infants.. Pediatr Pulmonol, 11(3), 217 - 222.
    • Childs HJ, Dezateux CA (1991). A national survey of nebuliser use.. Arch Dis Child, 66(11), 1351 - 1353.

    1986

    • Dezateux CA, Dinwiddie R, Helms P, Matthew DJ (1986). Recognition and early management of Reye's syndrome.. Arch Dis Child, 61(7), 647 - 651.

    1984

    • Dezateux CA, Hyde JC, Hoey HM, O'Riordan JL, Spitz L, Taylor GW, Grant DB (1984). Neonatal hyperparathyroidism.. Eur J Pediatr, 142(2), 135 - 136.
    • Burn J, Dezateux C, Hall CM, Baraitser M (1984). Orofaciodigital syndrome with mesomelic limb shortening.. J Med Genet, 21(3), 189 - 192.
    • SALISBURY DM, LEONARD JV, DEZATEUX CA, SAVAGE MO (1984). LESSON OF THE WEEK - MICROPENIS - AN IMPORTANT EARLY SIGN OF CONGENITAL HYPOPITUITARISM. BRIT MED J, 288(6417), 621 - 622.