Prof Dallas Swallow

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Personal Profile

Name: Dallas Swallow Email: d.swallow@ucl.ac.uk
Title: Prof Tel: 20 7679 7320
Department: Genetics, Evolution & Environment Fax:
Position: Emeritus Professor of Human Genetics Address: Darwin Building, Gower Street, London, WC1E 6BT
Research Domain: Basic Life Sciences, Infection, Immunology & Inflammation, Personalised Medicine Web Page: Personal Web Page

Profile

Research Description

I am interested in the origin and significance of functional variation in epithelial proteins - molecules located at the barrier between the 'inside' and the 'outside' of the body - in particular mucins (MUCs) and digestive enzymes such as lactase. We study inter-individual variation at the DNA level as well as looking at the RNA and protein products of these genes and asking questions about gene/environment interactions. For example, together with others in the Research Department of Genetics, Evolution and Environment, we are pursuing the molecular basis and evolutionary significance of the lactase persistence polymorphism.

Research Activities

Human genetic variation affecting function

drug metabolising enzymes

gastrointestinal tract

lactase

mucins

respiratory function,

Education Description

also teach on BIOL2006

UCL Collaborators

Prof Andres Ruiz-Linares; Dr Brian King

External Collaborators

Publications

    2013

    • Butt MA, Oukrif D, Haidry RJ, Rashid M, Khan S-U-R, Pye H, Bloom ES, Deonarain M, Swallow D, Banks MR, Rodriguez-Justo M, Novelli M, Lovat LB (2013). CHARACTERISATION OF OESOPHAGEAL MUC1 EXPRESSION IN THE PROGRESSION TO OESOPHAGEAL ADENOCARCINOMA. doi:10.1136/gutjnl-2013-304907.249
    • Johnson L, Shah I, Loh AX, Vinall LE, Teixeira AS, Rousseau K, Holloway JW, Hardy R, Swallow DM (2013). MUC5AC and inflammatory mediators associated with respiratory outcomes in the British 1946 birth cohort.. Respirology, 18(6), 1003 - 1010. doi:10.1111/resp.12092
    • Rashid M, Teixeira AS, Qureshi U, Pereira SP, Novelli MR, Swallow DM (2013). Apical MUC1 expression revealed on the foveolar epithelium in H. pylori gastritis. British Journal of Cancer, 108(5), 1113 - 1118.
    • Elding H, Lau W, Swallow DM, Maniatis N (2013). Refinement in localization and identification of gene regions associated with Crohn disease. Am J Hum Genet, 92, 107 - 113.
    • Jones BL, Raga TO, Liebert A, Zmarz P, Bekele E, Danielsen ET, Olsen AK, Bradman N, Troelsen JT, Swallow DM (2013). Diversity of Lactase Persistence Alleles in Ethiopia: Signature of a Soft Selective Sweep.. Am J Hum Genet, , - . doi:10.1016/j.ajhg.2013.07.008

    2012

    • Rousseau K, Swallow DM (2012). Mucin methods: Genes encoding mucins and their genetic variation with a focus on gel-forming mucins. Methods in Molecular Biology, 842, 1 - 26. doi:10.1007/978-1-61779-513-8_1
    • Gallego Romero I, Basu Mallick C, Liebert A, Crivellaro F, Chaubey G, Itan Y, Metspalu M, Eaaswarkhanth M, Pitchappan R, Villems R, Reich D, Singh L, Thangaraj K, Thomas MG, Swallow DM, Mirazón Lahr M, Kivisild T (2012). Herders of Indian and European cattle share their predominant allele for lactase persistence.. Mol Biol Evol, 29(1), 249 - 260. doi:10.1093/molbev/msr190

    2011

    • Horsfall LJ, Zeitlyn D, Tarekegn A, Bekele E, Thomas MG, Bradman N, Swallow DM (2011). Prevalence of clinically relevant UGT1A alleles and haplotypes in African populations.. Ann Hum Genet, 75(2), 236 - 246. doi:10.1111/j.1469-1809.2010.00638.x
    • Gerbault P, Liebert A, Itan Y, Powell A, Currat M, Burger J, Swallow DM, Thomas MG (2011). Evolution of lactase persistence: an example of human niche construction.. Philos Trans R Soc Lond B Biol Sci, 366(1566), 863 - 877. doi:10.1098/rstb.2010.0268
    • Horsfall LJ, Rait G, Walters K, Swallow DM, Pereira SP, Nazareth I, Petersen I (2011). Serum bilirubin and risk of respiratory disease and death.. JAMA, 305(7), 691 - 697. doi:10.1001/jama.2011.124
    • Guo XL, Pace RG, Stonebraker JR, Commander CW, Dang AT, Drumm ML, Harris A, Zou F, Swallow DM, Wright FA, O'Neal WK, Knowles MR (2011). Mucin Variable Number Tandem Repeat Polymorphisms and Severity of Cystic Fibrosis Lung Disease: Significant Association with MUC5AC. PLOS ONE, 6(10), - . doi:10.1371/journal.pone.0025452
    • Elding H, Lau W, Swallow DM, Maniatis N (2011). Dissecting the genetics of complex inheritance: linkage disequilibrium mapping provides insight into Crohn disease.. Am J Hum Genet, 89(6), 798 - 805. doi:10.1016/j.ajhg.2011.11.006
    • Jones BL, Swallow DM (2011). The impact of cis-acting polymorphisms on the human phenotype. HUGO Journal, 5(1-4), 13 - 23. doi:10.1007/s11568-011-9155-4
    • Jensen TGK, Liebert A, Lewinsky R, Swallow DM, Olsen J, Troelsen JT (2011). The -14010*C variant associated with lactase persistence is located between an Oct-1 and HNF1 alpha binding site and increases lactase promoter activity. HUM GENET, 130(4), 483 - 493. doi:10.1007/s00439-011-0966-0

    2010

    • Loh AX, Johnson L, Ng W, Swallow DM (2010). Cis-acting allelic variation in MUC5B mRNA expression is associated with different promoter haplotypes.. Ann Hum Genet, 74(6), 498 - 505. doi:10.1111/j.1469-1809.2010.00613.x
    • Itan Y, Jones BL, Ingram CJ, Swallow DM, Thomas MG (2010). A worldwide correlation of lactase persistence phenotype and genotypes.. BMC Evol Biol, 10, 36 - . doi:10.1186/1471-2148-10-36

    2009

    • Ingram CJ, Raga TO, Tarekegn A, Browning SL, Elamin MF, Bekele E, Thomas MG, Weale ME, Bradman N, Swallow DM (2009). Multiple rare variants as a cause of a common phenotype: several different lactase persistence associated alleles in a single ethnic group.. J Mol Evol, 69(6), 579 - 588. doi:10.1007/s00239-009-9301-y
    • Black S, Teixeira AS, Loh AX, Vinall L, Holloway JW, Hardy R, Swallow DM (2009). Contribution of functional variation in the IL13 gene to allergy, hay fever and asthma in the NSHD longitudinal 1946 birth cohort.. Allergy, 64(8), 1172 - 1178. doi:10.1111/j.1398-9995.2009.01988.x
    • Ingram CJE, Mulcare CA, Thomas MG, Swallow DM, Itan Y (2009). Lactose digestion and the evolutionary genetics of lactase persistence. Human Genetics, 124(6), 579 - 591. doi:10.1007/s00439-008-0593-6
    • Ingram CJE, Swallow DM (2009). Lactose malabsorption. Advanced Dairy Chemistry, 3, 203 - 229. doi:10.1007/978-0-387-84865-5_6
    • Ingram CJE, Mulcare CA, Itan Y, Thomas MG, Swallow DM (2009). Lactose digestion and the evolutionary genetics of lactase persistence. HUM GENET, 124(6), 579 - 591. doi:10.1007/s00439-008-0593-6

    2008

    • Tag CG, Oberkanins C, Kriegshauser G, Ingram CJE, Swallow DM, Gressner AM, Ledochowski M, Weiskirchen R (2008). Evaluation of a novel reverse-hybridization StripAssay for typing DNA variants useful in diagnosis of adult-type hypolactasia. CLIN CHIM ACTA, 392(1-2), 58 - 62.
    • Matull WR, Andreola F, Loh A, Adiguzel Z, Deheragoda M, Qureshi U, Batra SK, Swallow DM, Pereira SP (2008). MUC4 and MUC5AC are highly specific tumour-associated mucins in biliary tract cancer. BRIT J CANCER, 98(10), 1675 - 1681. doi:10.1038/sj.bjc.6604364
    • Bartlett NW, Walton RP, Edwards MR, Aniscenko J, Caramori G, Zhu J, Glanville N, Choy KJ, Jourdan P, Burnet J, Tuthill TJ, Pedrick MS, Hurle MJ, Plumpton C, Sharp NA, Bussell JN, Swallow DM, Schwarze J, Guy B, Almond JW, Jeffery PK, Lloyd CM, Papi A, Killington RA, Rowlands DJ, Blair ED, Clarke NJ, Johnston SL (2008). Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation.. Nature Medicine, 14(2), 199 - 204. doi:10.1038/nm1713
    • Ng W, Loh AXW, Teixeira AS, Pereira SP, Swallow DM (2008). Genetic regulation of MUC1 alternative splicing in human tissues. BRIT J CANCER, 99(6), 978 - 985. doi:10.1038/sj.bjc.6604617

    2007

    • Weiskirchen R, Tag CG, Mengsteab S, Gressner AM, Ingram CJASDM (2007). Pitfalls in LightCycler diagnosis of the single-nucleotide polymorphism 13.9 kb upstream of the lactase gene that is associated with adult-type hypolactasia.. Clinica Chimica Acta, 384, 93 - 98.
    • Ingram CJE, Elamin MF, Mulcare CA, Weale ME, Tarekegn A, Raga TO, Bekele E, Elamin FM, Thomas MG, Bradman N, Swallow DM (2007). A novel polymorphism associated with lactose tolerance in Africa: multiple causes for lactase persistence?. HUM GENET, 120(6), 779 - 788. doi:10.1007/s00439-006-0291-1
    • Guo XL, O'Neal WK, Yeatts JP, Swallow DM, Pace RG, Stonebraker JR, Zariwala MA, Harris A, Wright FA, Zou F, Perez-Vilar J, Knowles MR (2007). Assessing mucin gene polymorphisms to determine their role as modifiers of different CF phenotypes.
    • Matull WR, Loh A, Andreola F, Adiguzel Z, Deheragoda M, Qureshi U, Swallow DM, Pereira SP (2007). Are MUC4 and/or MUC5AC useful tumour markers for biliary tract cancer?.
    • Ingram CJE, Elamin MF, Mulcare CA, Swallow DM, Weale ME, Tarekegn A, Thomas MG, Bradman N, Elamin FM, Raga TO, Bekele E (2007). A novel polymorphism associated with lactose tolerance in Africa: Multiple causes for lactase persistence?. Human Genetics, 120(6), 779 - 788. doi:10.1007/s00439-006-0291-1
    • Rousseau K, Byrne C, Griesinger G, Leung A, Chung A, Hill AS, Swallow DM (2007). Allelic association and recombination hotspots in the mucin gene (MUC) complex on chromosome 11p15.5.. Ann Hum Genet, 71(Pt 5), 561 - 569. doi:10.1111/j.1469-1809.2007.00374.x

    2006

    • Swallow DM, Teixeira A, Rousseau K (2006). Mucins secreted and membrane associated; heterogeneity in health and disease. The Brush Border Membrane. In Naim HY, Zimmer KP (Ed.), From Cell Biology to Clinical Pathology. Perspectives in Pediatric Gastroenterology (pp. - ). : SPS publications.
    • Swallow DM (2006). DNA test for hypolactasia premature. GUT, 55(1), 131 - 131.
    • Rousseau K, Vinall LE, Butterworth SL, Hardy RJ, Holloway J, Wadsworth MEJ, Swallow DM (2006). MUC7 haplotype analysis: Results from a longitudinal birth cohort support protective effect of the MUC7*5 allele on respiratory function. ANN HUM GENET, 70, 417 - 427.

    2004

    • Leteurtre E, Rousseau K, Gouyer V, Swallow DM (2004). Differential mucin expression in colon carcinoma HT-29. Biology of the Cell, 96(2), 145 - 151.
    • Phillips AD, Brown A, Swallow DM, Hicks S, Schuller S, Murch SH, Walker-Smith JA (2004). Acetylated sialic acid residues and blood group antigens localise within the epithelium in microvillous atrophy indicating internal accumulation of the glycocalyx. GUT, 53(12), 1764 - 1771. doi:10.1136/gut.2004.041954
    • Rousseau K, Byrne C, Kim YS, Gum JR, Swallow DM, Toribara NW (2004). The complete genomic organization of the human MUC6 and MUC2 mucin genes. GENOMICS, 83(5), 936 - 939. doi:10.1016/j.ygeno.2003.11.003
    • Teixeira A, Silva F, Carvalho F, Fowler J, Vinall LE, Lovat L, Sarner M, David L, Swallow DM (2004). Muc1 hypervariability in gastric and oesophageal disease.
    • Mulcare CA, Weale ME, Jones AL, Connell B, Zeitlyn D, Tarekegn A, Swallow DM, Bradman N, Thomas MG (2004). The T allele of a single-nucleotide polymorphism 13.9 kb upstream of the lactase gene (LCT) (C-13.9kbT) does not predict or cause the lactase-persistence phenotype in Africans. AM J HUM GENET, 74(6), 1102 - 1110.
    • Leteurtre E, Gouyer V, Rousseau K, Moreau O, Barbat A, Swallow D, Huet G, Lesuffleur T (2004). Differential mucin expression in colon carcinoma HT-29 clones with variable resistance to 5-fluorouracil and methotrexate. BIOL CELL, 96(2), 145 - 151. doi:10.1016/j.biolcel.2003.12.005
    • Wadsworth MEJ, Vinall LE, Jones AL, Hardy RJ, Whitehouse DB, Butterworth SL, Hilder WS, Lovegrove JU, Swallow DM (2004). Alpha(1)-antitrypsin as a risk for infant and adult respiratory outcomes in a national birth cohort. AM J RESP CELL MOL, 31(5), 559 - 564. doi:10.1065/rcmb.2004-0027OC
    • O'Donnell RA, Richter A, Ward J, Angco G, Mehta A, Rousseau K, Swallow DM, Holgate ST, Djukanovic R, Davies DE, Wilson SJ (2004). Expression of ErbB receptors and mucins in the airways of long term current smokers. THORAX, 59(12), 1032 - 1040. doi:10.1136/thx.2004.028043
    • Mulcare CA, Weale ME, Jones AL, Tarekegn A, Bradman N, Thomas MG, Swallow DM, Connell B, Zeitlyn D (2004). The T allele of a single-nucleotide polymorphism 13.9 kb upstream of the lactase gene (LCT) (C - 13.9kbT) does not predict or cause the lactase-persistence phenotype in africans. American Journal of Human Genetics, 74(6), 1102 - 1110. doi:10.1086/421050

    2003

    • Nichols BL, Avery S, Sen P, Swallow DM, Hahn D, Sterchi E (2003). The maltase-glucoamylase gene: Common ancestry to sucrase-isomaltase with complementary starch digestion activities. P NATL ACAD SCI USA, 100(3), 1432 - 1437. doi:10.1073/pnas.0237170100
    • Fowler JC, Teixeira AS, Vinall LE, Swallow DM (2003). Hypervariability of the membrane-associated mucin and cancer marker MUC1. Human Genetics, 113(6), 473 - 479. doi:10.1007/s00439-003-1011-8
    • Rousseau K, Vinall LE, Holloway JA, Swallow DM (2003). The genetic variation of the small mucin gene MUC7.
    • Park HU, Kim JW, Kim GE, Bae HI, Crawley SC, Yang SC, Gum JR, Batra SK, Rousseau K, Swallow DM, Sleisenger MH, Kim YS (2003). Aberrant expression of MUC3 and MUC4 membrane-associated mucins and sialyl Le(x) antigen in pancreatic intraepithelial neoplasia. Pancreas, 26(3), 48 - 54.
    • Swallow DM (2003). EU-MUC5Ba and MUC5Bb against MUC5B.
    • Poulter M, Hollox E, Harvey CB, Mulcare C, Peuhkuri K, Kajander K, Sarner M, Korpela R, Swallow DM (2003). The causal element for the lactase persistence/non-persistence polymorphism is located in a 1 Mb region of linkage disequilibrium in Europeans. ANN HUM GENET, 67, 298 - 311.
    • Nemeth K, Plumb GW, Berrin JG, Juge N, Jacob R, Naim HY, Williamson G, Swallow DM, Kroon PA (2003). Deglycosylation by small intestinal epithelial cell beta-glucosidases is a critical step in the absorption and metabolism of dietary flavonoid glycosides in humans. EUROPEAN JOURNAL OF NUTRITION, 42(1), 29 - 42. doi:10.1007/s00394-003-0397-3
    • Swallow DM (2003). Genetic influences on carboydrate digestion. Nutrition Research Reviews, 16, 37 - 43.
    • Swallow DM (2003). Genetics of lactase persistence and lactose intolerance.. Annu Rev Genet, 37, 197 - 219. doi:10.1146/annurev.genet.37.110801.143820
    • Rousseau K, Wickstrom C, Whitehouse DB, Carlstedt I, Swallow DM (2003). New monoclonal antibodies to non-glycosylated domains of the secreted mucins MUC5B and MUC7. HYBRIDOMA HYBRIDOM, 22(5), 293 - 299.
    • Swallow DM (2003). EU-MUC7a against MUC7.

    2002

    • Hollox EJ, Swallow DM (2002). Lactase deficiency: Biological and Medical Aspects of the human lactase polymorphism. In King RA, Rotter JI, Motulsky AG (Ed.), The Genetic Basis of Common Diseases (pp. - ). : Oxford University Press.
    • Vinall LE, King M, Novelli M, Green CA, Daniels G, Hilkens J, Sarner M, Swallow DM (2002). Altered expression and allelic association of the hypervariable membrane mucin MUC1 in Helicobacter pylori gastritis. GASTROENTEROLOGY, 123(1), 41 - 49. doi:10.1053/gast.2002.34157
    • Nichols B, Avery S, Karnsakul W, Jahoor F, Sen P, Swallow DM, Luginbuehl U, Hahn D, Sterchi E (2002). Congenital maltase-glucoamylase deficiency associated with lactase and sucrase deficiencies. Journal of Pediatric Gastroenterology and Nutrition, 35(573), 579 - .
    • Nichols BL, Avery SE, Karnsakul W, Jahoor F, Sen P, Swallow DM, Luginbuehl U, Hahn D, Sterchi EE (2002). Congenital maltase-glucoamylase deficiency associated with lactase and sucrase deficiencies. J PEDIATR GASTR NUTR, 35(4), 573 - 579.
    • Karnsakul W, Hahn D, Sterchi E, Avery S, Sen P, Swallow D, Nichols B (2002). Disaccharide activities in dyspeptic children.
    • Karnsakul W, Luginbuehl U, Hahn D, Sterchi E, Avery S, Sen P, Swallow DM, Nichols B (2002). Disaccharide activities in dyspeptic children: biochemical and molecular investigations of maltase-glucoamylase activity. Journal of Pediatric Gastroenterology and Nutrition, 35, 551 - 556.
    • Hollox DM, Swallow DM (2002). Lactase Deficiency. In (Ed.), Oxford Monographs on Medical Genetics (pp. - ). : Oxford University Press.
    • Teixeira A, Fowler J, Vinall LE, Lovat L, Sarner M, Swallow DM (2002). Polymorphisms of the MUC1 gene and haplotype analysis in healthy individuals and in patients with gastric and oesophageal diseases.
    • Rousseau K, Vinall LE, Holloway JA, Swallow DM (2002). The genetic variation of the small mucin gene MUC7.

    2001

    • (2001). MUC1 gene polymorphism in the gastric carcinogenesis pathway. European Journal of Human Genetics, 9, 548 - 552.
    • Fowler J, Vinall LE, Swallow DM (2001). Minisatellite variant repeat (MVR) analysis of the tandem repeat region of the MUC1 gene.
    • Hollox EJ, Poulter M, Zvarik M, Ferak V, Krause A, Jenkins T, Saha N, Kozlov AI, Swallow DM (2001). Lactase haplotype diversity in the Old World. AM J HUM GENET, 68(1), 160 - 172.
    • Kirkbride HJ, Bolscher JG, Nazmi K, Vinall LE, Nash MW, Moss FM, Mitchell DM, Swallow DM (2001). Genetic polymorphism of MUC7: allele frequencies and association with asthma.. Eur J Hum Genet, 9(5), 347 - 354. doi:10.1038/sj.ejhg.5200642
    • Karnsakul W, Lifschitz C, Kitagawa S, Olive A, Villa X, Avery S, Sterchi EE, Hahn D, Lugenbuehl U, Swallow DM, Nichols BL (2001). Pandisaccharidase deficiencies in chronic abdominal pain..
    • King M, Vinall LE, Novelli M, Sarner M, Swallow DM (2001). MUC1 in Heliobacter gastritis.
    • Fowler J, Vinall LE, Swallow DM (2001). Polymorphism of the human MUC genes. In (Ed.), (pp. - ). : .

    2000

    • Leiper K, Rhodes JM, Swallow DM, Campbell BJ (2000). The putative IBD gene DRA (down regulated in adenoma) is normal at the DNA, RNA and protein levels in ulcerative colitis..
    • Leiper K, Rhodes JM, Swallow DM, Campbell BJ (2000). The putative IBD gene DRA (Down regulated in adenoma) is normal at the DBA, RNA, protein levels in ulcerative colitis.
    • Swallow DM, Hollox EJ (2000). The genetic polymorphism of intestinal lactase activity in adult humans. In Scriver CR, Beaudet AL, Sly WS, Valle D (Ed.), Metabolic basis of inherited disease (pp. 1651 - 1663). : McGraw-Hill.
    • Gum Jr JR, Crawley SC, Hicks JW, Ho JJL, Kim YS, Pratt WS, Swallow DM (2000). MUC3: Structure and possible functions.
    • Hollox EJ, Poulter M, Swallow DM (2000). Lactase haplotype diversity in the old world. In Renfrew C, Boyle K (Ed.), Archaeogenetics: DNA and the population prehistory of Europe (pp. 305 - 308). : K. Macdonald Institute Monographs.
    • Vinall LE, Pratt WS, Swallow DM (2000). Detection of mucin gene polymorphism. In Corfield AP (Ed.), Mucin Methods and Protocols - Methods in Molecular Biology (pp. 337 - 352). : Humana Press.
    • Poulter M, Hollox EJ, Harvey CB, Korpela R, Swallow DM (2000). The Cis-Element Determining Lactase Persistence: Localisation by decay of single nucleotide polymorphism (SNP) haplotype sharing.
    • Vinall LE, Fowler JC, Jones AL, Kirkbride HJ, de Bolos C, Laine A, Porchet N, Gum JR, Kim YS, Moss FM, Mitchell DM, Swallow DM (2000). Polymorphism of human mucin genes in chest disease - Possible significance of MUC2. AM J RESP CELL MOL, 23(5), 678 - 686.
    • Nichols BL, Kamsakul W, Avery SE, Swallow D, Hahn D, Sterchi EE (2000). Trans-suppression of maltase-glucoamylase activity in an infant with congenital lactase and sucrase deficiencies.
    • Pratt WS, Crawley S, Hicks J, Ho J, Nash M, Kim YS, Gum JR, Swallow DM (2000). Multiple transcripts of MUC3: evidence for two genes, MUC3A and MUC3B.. Biochem Biophys Res Commun, 275(3), 916 - 923. doi:10.1006/bbrc.2000.3406

    1999

    • Swallow DM, Vinall LE, Gum JR, Kim YS, Yang HY, Rotter JI, Mirza M, Lee JCW, Lennard-Jones JE (1999). Ulcerative colitis is not associated with differences in MUC2 mucin allele length. J MED GENET, 36(11), 859 - 860.
    • Herrmann A, Davies JR, Lindell G, Martensson S, Packer NH, Swallow DM, Carlstedt I (1999). Studies on the "insoluble" glycoprotein complex from human colon - Identification of reduction-insensitive MUC2 oligomers and C-terminal cleavage. J BIOL CHEM, 274(22), 15828 - 15836.
    • Crawley SC, Gum JR, Hicks JW, Pratt WS, Aubert J-P, Swallow DM, Kim YS (1999). Genomic organisation and structure of the 3' region of human MUC3: alternative splicing predicts membrane-bound and soluble forms of the mucin. Biochemical and Biophysical Research Communications, 263, 728 - 736.
    • Hollox EJ, Poulter M, Wang YX, Krause A, Swallow DM (1999). Common polymorphism in a highly variable region upstream of the human lactase gene affects DNA-protein interactions. EUR J HUM GENET, 7(7), 791 - 800.
    • Hollox EJ, Poulter M, Zvarik M, Ferak V, Krause A, Jenkins T, Saha N, Kozlov A, Swallow DM (1999). Lactase haplotype diversity in the Old World..

    1998

    • Harvey CB, Hollox EJ, Poulter M, Wang Y, Rossi M, Auricchio S, Iqbal TH, Cooper BT, Barton R, Sarner M, Korpela R, Swallow DM (1998). Lactase haplotype frequencies in Caucasians: association with the lactase persistence/non-persistence polymorphism. ANNALS OF HUMAN GENETICS, 62, 215 - 223.
    • Wang Y, Harvey CB, Hollox EJ, Phillips AD, Poulter M, Clay P, Walker-Smith JA, Swallow DM (1998). The genetically programmed down-regulation of lactase in children.. Gastroenterology, 114(6), 1230 - 1236.
    • Vinall LE, Hill AS, Pigny P, Pratt WS, Toribara N, Gum JR, Kim YS, Porchet N, Aubert JP, Swallow DM (1998). Variable number tandem repeat polymorphism of the mucin genes located in the complex on 11p15.5.. Hum Genet, 102(3), 357 - 366.
    • Waltz MR, Pandelidis SM, Pratt W, Barnes D, Swallow DM, Gendler SJ, Cohen EP (1998). A microsatellite within the MUC1 locus at 1q21 is altered in the neoplastic cells of breast cancer patients. CANCER GENET CYTOGEN, 100(1), 63 - 67.

    1997

    • Swallow DM, Edwards YH (1997). Editors of "Protein Dysfunction in Human Genetic Disease".
    • Vinall LE, Robertson AM, Swallow DM, Kim YS (1997). MUC3 Human intestinal mucin: Analysis of gene structure, the carboxyl terminus and a novel upstream repetitive region. Journal of Biological Chemistry, 272, 26678 - 26686.
    • Edwards YH, Swallow DM (1997). "Protein Dysfunction in Human Genetic Disease". In (Ed.), (pp. 1 - 13). : .

    1996

    • Filipe MI, Linehan JM, Durrant LG, Price MR, Smeeton NC, Pathak S, Swallow DM (1996). Expression of a peptide epitope of the colonic mucin MUC2 in precursor lesions to gastric carcinoma. EUR J CANCER PREV, 5(4), 287 - 295.
    • Pratt WS, Islam I, Swallow DM (1996). Two additional polymorphisms within the hypervariable MUC1 gene: association of alleles either side of the VNTR region.. Ann Hum Genet, 60(Pt 1), 21 - 28.
    • Pigny P, Guyonnet-Duperat V, Laine A, Van-Seuningen I, Degand P, Aubert J-P, Porchet N, Galiegue-Zouitina S, D'Hooge MC, Hill AS, Pratt WS, Swallow DM, Gum JR, Kim YS (1996). Human mucin genes assigned to 11p15.5: Identification and organization of a cluster of genes. Genomics, 38(3), 340 - 352. doi:10.1006/geno.1996.0637
    • Rodolosse A, Chantret I, Lacasa M, Chevalier G, Zweibaum A, Rousset M, Swallow D (1996). A limited upstream region of the human sucrase-isomaltase gene confers glucose-regulated expression on a heterologous gene. Biochemical Journal, 315(1), 301 - 306.
    • Harvey CB, Wang Y, Darmoul D, Phillips A, Mantei N, Swallow DM (1996). Characterisation of a human homologue of a yeast cell division cycle gene, MCM6, located adjacent to the 5' end of the lactase gene on chromosome 2q21.. FEBS Lett, 398(2-3), 135 - 140.

    1995

    • Harvey CB, Wang Y, Hughes LA, Swallow DM, Thurrell WP, Sams VR, Barton R, Lanzon-Miller S, Sarner M (1995). Studies on the expression of intestinal lactase in different individuals.. Gut, 36(1), 28 - 33.
    • HILL AS, GUM JR, HO J, PRATT W, BECK S, KIM YS, SWALLOW DM (1995). GENETIC AND PHYSICAL MAPPING OF THE REGION SURROUNDING MUC3 ON 7Q22.
    • Harvey CB, Pratt WS, Islam I, Whitehouse DB, Swallow DM (1995). DNA polymorphisms in the lactase gene. Linkage disequilibrium across the 70-kb region.. Eur J Hum Genet, 3(1), 27 - 41.
    • Harvey CB, Pratt WS, Islam I, Whitehouse DB, Swallow DM (1995). DNA polymorphisms in the lactase gene. European Journal of Human Genetics, 3(1), 27 - 41.
    • Wang Y, Harvey CB, Pratt WS, Sams VR, Sarner M, Rossi M, Auricchio S, Swallow DM (1995). The lactase persistence/non-persistence polymorphism is controlled by a cis-acting element.. Hum Mol Genet, 4(4), 657 - 662.
    • TYTGAT KMAJ, SWALLOW DM, VANKLINKEN BJW, BULLER HA, EINERHAND AWC, DEKKER J (1995). UNPREDICTABLE BEHAVIOR OF MUCINS IN SDS POLYACRYLAMIDE-GEL ELECTROPHORESIS. BIOCHEM J, 310, 1053 - 1054.
    • Lesuffleur T, Lacasa M, Zweibaum A, Roche F, Real FX, Hill AS, Fox M, Swallow DM (1995). Characterization of a mucin cDNA clone isolated from HT-29 mucus-secreting cells: The 3′ end of MUC5AC?. Journal of Biological Chemistry, 270(23), 13665 - 13673.

    1994

    • Darmoul D, Fox M, Harvey C, Swallow DM, Jeggo P, Gum JR, Kim YS (1994). Regional localization of DPP4 (alias CD26 and ADCP2) to chromosome 2q24. Somatic Cell and Molecular Genetics, 20(4), 345 - 351. doi:10.1007/BF02254723
    • Ring SM, Green CA, Swallow DM, Tippett P (1994). Production of a murine monoclonal antibody to the low-incidence red cell antigen Wra: characterisation and comparison with human anti-Wra.. Vox Sang, 67(2), 222 - 225.
    • HILL AS, PRATT WS, ATTWOOD J, ROBSON EB, SWALLOW DM (1994). POLYMORPHISM OF THE MUC3 GENE AND ITS LOCALIZATION WITHIN A PRELIMINARY FRAMEWORK MAP OF CHROMOSOME-7.
    • Ring SM, Tippett P, Swallow DM (1994). Comparative immunochemical analysis of Wra and Wrb red cell antigens.. Vox Sang, 67(2), 226 - 230.
    • MAIURI L, ROSSI M, RAIA V, GARIPOLI V, HUGHES LA, SWALLOW D, NOREN O, SJOSTROM H, AURICCHIO S (1994). MOSAIC REGULATION OF LACTASE IN HUMAN ADULT-TYPE HYPOLACTASIA. GASTROENTEROLOGY, 107(1), 54 - 60.
    • DARMOUL D, VOISIN T, COUVINEAU A, ROUYERFESSARD C, SALOMON R, WANG YX, SWALLOW DM, LABURTHE M (1994). REGIONAL EXPRESSION OF EPITHELIAL DIPEPTIDYL PEPTIDASE-IV IN THE HUMAN INTESTINES. BIOCHEM BIOPH RES CO, 203(2), 1224 - 1229.
    • Wang Y, Harvey C, Rousset M, Swallow DM (1994). Expression of human intestinal mRNA transcripts during development: analysis by a semiquantitative RNA polymerase chain reaction method.. Pediatr Res, 36(4), 514 - 521. doi:10.1203/00006450-199410000-00018
    • Povey S, Attwood J, Bakker E, Swallow DM, Vergnaud G (1994). The EUROGEM map of human chromosome 11.. Eur J Hum Genet, 2(3), 224 - 225.

    1993

    • Swallow DM, Islam I, Fox MF, Povey S, Klima H, Schepers U, Sandhoff K (1993). Regional localization of the gene coding for the GM2 activator protein (GM2A) to chromosome 5q32-33 and confirmation of the assignment of GM2AP to chromosome 3.. Ann Hum Genet, 57(Pt 3), 187 - 193.
    • Harvey CB, Fox MF, Jeggo PA, Mantei N, Povey S, Swallow DM (1993). Regional localization of the lactase-phlorizin hydrolase gene, LCT, to chromosome 2q21.. Ann Hum Genet, 57(Pt 3), 179 - 185.

    1992

    • Fox MF, Lahbib F, Pratt W, Attwood J, Gum J, Kim Y, Swallow DM (1992). Regional localization of the intestinal mucin gene MUC3 to chromosome 7q22.. Ann Hum Genet, 56(Pt 4), 281 - 287.
    • Chantret I, Lacasa M, Chevalier G, Ruf J, Islam I, Mantei N, Edwards Y, Swallow D, Rousset M (1992). Sequence of the complete cDNA and the 5' structure of the human sucrase-isomaltase gene. Possible homology with a yeast glucoamylase.. Biochem J, 285 ( Pt 3), 915 - 923.

    1990

    • Griffiths B, Matthews DJ, West L, Attwood J, Povey S, Swallow DM, Gum JR, Kim YS (1990). Assignment of the polymorphic intestinal mucin gene (MUC2) to chromosome 11p15.. Ann Hum Genet, 54(Pt 4), 277 - 285.
    • HOPKINSON DA, SWALLOW DM, MARINAKI A, HARLEY EH (1990). PYRIMIDINE 5'-NUCLEOTIDASE ACTIVITY IN NORMAL AND DEFICIENT HUMAN LYMPHOBLASTOID-CELLS. J INHERIT METAB DIS, 13(5), 701 - 706.

    1989

    • PAN LX, BEVERLEY PCL, BOBROW LG, SWALLOW DM, ISAACSON PG (1989). PRODUCTION OF MONOCLONAL-ANTIBODIES TO LACTATE-DEHYDROGENASE (LDH) ISOENZYMES FOR IMMUNOHISTOCHEMICAL STUDY ON FIXED TISSUE SECTION. HISTOCHEM J, 21(11), 638 - 644.
    • Swallow DM, Kroos M, Van der Ploeg AT, Griffiths B, Islam I, Marenah CB, Reuser AJ (1989). An investigation of the properties and possible clinical significance of the lysosomal alpha-glucosidase GAA*2 allele.. Ann Hum Genet, 53(Pt 2), 177 - 184.

    1988

    • Swallow DM, Griffiths B, Noades J, Corney G (1988). Linkage between the expressed hypervariable gene locus PUM and the gene coding for the Duffy blood group FY.. Ann Hum Genet, 52(Pt 4), 269 - 271.
    • West LF, Davis MB, Green FR, Lindenbaum RH, Swallow DM (1988). Regional assignment of the gene coding for human sucrase-isomaltase (SI) to chromosome 3q25-26.. Ann Hum Genet, 52(Pt 1), 57 - 61.
    • Griffiths B, Gordon A, Burchell J, Bramwell ME, Griffiths A, Price M, Taylor-Papadimitriou J, Zanin D, Swallow DM (1988). The breast tumour-associated epithelial mucins and the peanut lectin binding urinary mucins are coded by a single highly polymorphic gene locus 'PUM'.. Dis Markers, 6(3), 185 - 194.
    • Griffiths B, Bobrow LG, Happerfield L, Swallow DM (1988). Expression of the hypervariable PUM locus in normal and malignant lung: the tumor-associated epitopes are present but masked in normal tissue.. Dis Markers, 6(3), 195 - 202.

    1987

    • Swallow DM, Gendler S, Griffiths B, Corney G, Taylor-Papadimitriou J, Bramwell ME (1987). The human tumour-associated epithelial mucins are coded by an expressed hypervariable gene locus PUM. Nature, 328(6125), 82 - 84. doi:10.1038/328082a0
    • Green F, Edwards Y, Hauri HP, Povey S, Ho MW, Pinto M, Swallow D (1987). Isolation of a cDNA probe for a human jejunal brush-border hydrolase, sucrase-isomaltase, and assignment of the gene locus to chromosome 3.. Gene, 57(1), 101 - 110.

    1986

    • Swallow DM, Hopkinson DA (1986). Human biochemical genetics of enzyme proteins in the new age of molecular genetics.
    • Swallow DM, Griffiths B, Bramwell M, Wiseman G, Burchell J (1986). Detection of the urinary 'PUM' polymorphism by the tumour-binding monoclonal antibodies Ca1, Ca2, Ca3, HMFG1, and HMFG2.. Dis Markers, 4(4), 247 - 254.
    • Swallow DM, Povey S, Parkar M, Andrews PW, Harris H, Pym B, Goodfellow P (1986). Mapping of the gene coding for the human liver/bone/kidney isozyme of alkaline phosphatase to chromosome 1.. Ann Hum Genet, 50(Pt 3), 229 - 235.

    1985

    • Swallow DM, Potter J, Green F, Ho MW (1985). Preparation of a monclonal antibody against human lactase. Journal of Immunological Methods, 77(1), 139 - 145. doi:10.1016/0022-1759(85)90191-7

    1984

    • Swallow DM, West LF, Van Elsen A (1984). The role of lysosomal sialidase and β-galactosidase in processing the complex carbohydrate chains on lysosomal enzymes and possibly other glycoproteins. Annals of Human Genetics, 48(3), 215 - 221.
    • Griffiths BL, Karlsson S, Swallow DM, Soh CPC, Dawnay ABSJ (1984). Tamm-Horsfall glycoprotein: A lectin binding study. Glycoconjugate Journal, 1(2), 183 - 190. doi:10.1007/BF01213730
    • Karlsson S, Griffiths B, Swallow DM, Hopkinson DA, Wallis PG (1984). Glycoproteins in cystic fibrosis: A lectin binding study. Journal of Medical Genetics, 21(6), 441 - 446.

    1983

    • SHEER D, HIORNS LR, STANLEY KF, GOODFELLOW PN, SWALLOW DM, POVEY S, HEISTERKAMP N, GROFFEN J, STEPHENSON JR, SOLOMON E (1983). GENETIC-ANALYSIS OF THE 15-17 CHROMOSOME-TRANSLOCATION ASSOCIATED WITH ACUTE PROMYELOCYTIC LEUKEMIA. P NATL ACAD SCI-BIOL, 80(16), 5007 - 5011.
    • Davis MB, Swallow DM, Delhanty JDA (1983). Isozyme analysis of the large intestine with special reference to carcinoma of the colon and familial polyposis coli. Disease Markers, 1(4), 283 - 297.

    1979

    • SOLOMON E, SWALLOW D, BURGESS S, EVANS L (1979). ASSIGNMENT OF THE HUMAN ACID ALPHA-GLUCOSIDASE GENE (ALPHA-GLU) TO CHROMOSOME-17 USING SOMATIC-CELL HYBRIDS. ANN HUM GENET, 42(JAN), 273 - 281.

    1978

    • SWALLOW DM, SOLOMON E (1978). ASSIGNMENT OF GENE DETERMINING HUMAN ACID ALPHA-GLUCOSIDASE (ALPHA-GLU) USING SOMATIC-CELL HYBRIDS.
    • JAMIL TP, SWALLOW DM, POVEY S (1978). COMPARATIVE-STUDY OF THE AGE-RELATED PATTERNS OF DECAY OF SOME NUCLEOSIDE MONOPHOSPHATE KINASES IN HUMAN RED-CELLS. BIOCHEM GENET, 16(11-1), 1219 - 1232.
    • EDWARDS Y, SWALLOW D (1978). GENETIC-VARIANTS IN 2-D. NATURE, 272(5651), 309 - 310.

    1977

    • SWALLOW DM, EVANS L, HOPKINSON DA (1977). SEVERAL OF ADENOSINE-DEAMINASE ISOZYMES ARE GLYCOPROTEINS. NATURE, 269(5625), 261 - 262.
    • SWALLOW DM, GARDINER SE, HARRIS H, ARTHUR E, STEEL CM, EVANS HJ (1977). LYSOSOMAL ENZYMES IN HUMAN LYMPHOBLASTOID LINES - UNUSUAL CHARACTERISTICS OF RAJI AND DAUDI. ANN HUM GENET, 41(JUL), 9 - 16.
    • SOLOMON E, SWALLOW DM, PAJUNEN L (1977). IMMUNOCHEMICAL ANALYSIS OF HUMAN N-ACETYL HEXOSAMINIDASES IN HUMAN-MOUSE SOMATIC-CELL HYBRIDS. HEREDITY, 38(APR), 272 - 272.
    • GARDINER SE, SWALLOW DM, HARRIS H, ARTHUR E, EVANS HJ (1977). DEFICIENCY OF A LYSOSOMAL ACID HYDROLASE IN 2 CLONES DERIVED FROM HUMAN LYMPHOBLASTOID LINE F137 AFTER MUTAGEN TREATMENT. ANN HUM GENET, 41(JUL), 17 - 25.
    • SWALLOW DM, SOLOMON E, PAJUNEN L (1977). IMMUNOCHEMICAL ANALYSIS OF N-ACETYL HEXOSAMINIDASES IN HUMAN-MOUSE HYBRIDS MADE USING A DOUBLE SELECTIVE SYSTEM. CYTOGENET CELL GENET, 18(3), 136 - 148.

    1976

    • SWALLOW DM (1976). ACID ALPHA-GLUCOSIDASE - NEW POLYMORPHISM IN MAN DEMONSTRABLE BY AFFINITY ELECTROPHORESIS.
    • SOLOMON E, BOBROW M, GOODFELLOW PN, BODMER WF, SWALLOW DM, POVEY S, NOEL B (1976). HUMAN GENE MAPPING USING AN X-AUTOSOME TRANSLOCATION. SOMAT CELL GENET, 2(2), 125 - 140.
    • SWALLOW DM, EVANS L, SAHA N, HARRIS H (1976). CHARACTERIZATION AND TISSUE DISTRIBUTION OF N-ACETYL HEXOSAMINIDASE C - SUGGESTIVE EVIDENCE FOR A SEPARATE HEXOSAMINIDASE LOCUS. ANN HUM GENET, 40(JUL), 55 - 66.

    1975

    • HIRSCHHORN R, SWALLOW D, HARRIS H (1975). AFFINITY ELECTROPHORESIS - NEW PRINCIPLE FOR IDENTIFICATION OF ENZYME POLYMORPHISMS.
    • SWALLOW DM, CORNEY G, HARRIS H, HIRSCHHORN R (1975). ACID ALPHA-GLUCOSIDASE - NEW POLYMORPHISM IN MAN DEMONSTRABLE BY AFFINITY ELECTROPHORESIS. ANN HUM GENET, 38(MAY), 391 - 406.
    • BENGTSSON BO, NABHOLZ M, KENNETT R, BODMER WF, POVEY S, SWALLOW D (1975). HUMAN INTRASPECIFIC SOMATIC-CELL HYBRIDS - GENETIC AND KARYOTYPIC ANALYSIS OF CROSSES BETWEEN LYMPHOCYTES AND D98-AH-2. SOMAT CELL GENET, 1(1), 41 - 64.

    1974

    • POVEY S, SWALLOW DM, BOBROW M, CRAIG I, VANHEYNI.V (1974). PROBABLE ASSIGNMENT OF LOCUS DETERMINING HUMAN RED-CELL ACID-PHOSPHATASE ACP1 TO CHROMOSOME-2 USING SOMATIC-CELL HYBRIDS. ANN HUM GENET, 38(JUL), 1 - 5.
    • SWALLOW DM, STOKES DC, CORNEY G, HARRIS H (1974). DIFFERENCES BETWEEN N-ACETYL HEXOSAMINIDASE ISOENZYMES IN SERUM AND TISSUES. ANN HUM GENET, 37(JAN), 287 - 302.

    1973

    • SWALLOW DM, POVEY S, HARRIS H (1973). ACTIVITY OF RED-CELL ACID-PHOSPHATASE LOCUS IN OTHER TISSUES. ANN HUM GENET, 37(JUL), 31 - 38.

    • Ingram CJE, Liebert A, Swallow DM (). Population Genetics of Lactase Persistence and Lactose Intolerance.