Prof Shamshad Cockcroft

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Name: Shamshad Cockcroft Email: s.cockcroft@ucl.ac.uk
Title: Prof Tel: 0044 20 7679 6259
Department: Neuroscience, Physiology & Pharmacology Fax:
Position: Professor of Cell Physiology Address: Gower Street, , London, WC1E 6BT
Research Domain: Basic Life Sciences, Cancer, Infection Immunology & Inflammation, Neuroscience Web Page: Personal Web Page

Profile

Research Description


Research Activities

Lipids in Cell Signalling and Membrane traffic

Education Description

UCL Collaborators

External Collaborators

Publications

    2013

    • Skippen A, Swigart P, Cockcroft S (2013). Measurement of phospholipase C by monitoring inositol phosphates using [³H]inositol labeling protocols in permeabilized cells.. Methods Mol Biol, 937, 163 - 174. doi:10.1007/978-1-62703-086-1_9

    2012

    • Cockcroft S (2012). The diverse functions of phosphatidylinositol transfer proteins.. Curr Top Microbiol Immunol, 362, 185 - 208. doi:10.1007/978-94-007-5025-8_9
    • Garner K, Hunt AN, Koster G, Somerharju P, Groves E, Li M, Raghu P, Holic R, Cockcroft S (2012). Phosphatidylinositol transfer protein, cytoplasmic 1 (PITPNC1) binds and transfers phosphatidic acid.. J Biol Chem, 287(38), 32263 - 32276. doi:10.1074/jbc.M112.375840
    • Cockcroft S, Garner K (2012). 14-3-3 protein and ATRAP bind to the soluble class IIB phosphatidylinositol transfer protein RdgBβ at distinct sites.. Biochem Soc Trans, 40(2), 451 - 456. doi:10.1042/BST20110770

    2011

    • Cockcroft S, Garner K (2011). Function of the phosphatidylinositol transfer protein gene family: is phosphatidylinositol transfer the mechanism of action?. Crit Rev Biochem Mol Biol, 46(2), 89 - 117. doi:10.3109/10409238.2010.538664
    • Garner K, Li M, Ugwuanya N, Cockcroft S (2011). The phosphatidylinositol transfer protein RdgBβ binds 14-3-3 via its unstructured C-terminus, whereas its lipid-binding domain interacts with the integral membrane protein ATRAP (angiotensin II type I receptor-associated protein).. Biochem J, 439(1), 97 - 111. doi:10.1042/BJ20110649

    2010

    • Carvou N, Holic R, Li M, Futter C, Skippen A, Cockcroft S (2010). Phosphatidylinositol- and phosphatidylcholine-transfer activity of PITPbeta is essential for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum.. J Cell Sci, 123(Pt 8), 1262 - 1273. doi:10.1242/jcs.061986
    • Yanase Y, Carvou N, Frohman MA, Cockcroft S (2010). Reversible bleb formation in mast cells stimulated with antigen is Ca2+/calmodulin-dependent and bleb size is regulated by ARF6.. Biochem J, 425(1), 179 - 193. doi:10.1042/BJ20091122

    2009

    • Cockcroft S, Frohman M (2009). Special issue on phospholipase D.. Biochim Biophys Acta, 1791(9), 837 - 838. doi:10.1016/j.bbalip.2009.08.003
    • Cockcroft S (2009). Phosphatidic acid regulation of phosphatidylinositol 4-phosphate 5-kinases.. Biochim Biophys Acta, 1791(9), 905 - 912. doi:10.1016/j.bbalip.2009.03.007
    • Leber W, Skippen A, Fivelman QL, Bowyer PW, Cockcroft S, Baker DA (2009). A unique phosphatidylinositol 4-phosphate 5-kinase is activated by ADP-ribosylation factor in Plasmodium falciparum.. Int J Parasitol, 39(6), 645 - 653. doi:10.1016/j.ijpara.2008.11.015
    • Cockcroft S (2009). Measurement of phosphatidylinositol and phosphatidylcholine binding and transfer activity of the lipid transport protein PITP.. Methods Mol Biol, 462, 363 - 377. doi:10.1007/978-1-60327-115-8_23
    • Cockcroft S, Holic R, Carvou N (2009). Dynamics of lipid transfer by phosphatidylinositol transfer protein during membrane transport at the endoplasmic reticulum-Golgi membrane interface. FASEB JOURNAL, 23, - .
    • Kolman P, Pica A, Carvou N, Boyde A, Cockcroft S, Loesch A, Pizzey A, Simeoni M, Capasso G, Unwin RJ (2009). Insulin uptake across the luminal membrane of the rat proximal tubule in vivo and in vitro.. Am J Physiol Renal Physiol, 296(5), F1227 - F1237. doi:10.1152/ajprenal.90351.2008

    2008

    • Cosker KE, Shadan S, van Diepen M, Morgan C, Li M, Allen-Baume V, Hobbs C, Doherty P, Cockcroft S, Eickholt BJ (2008). Regulation of PI3K signalling by the phosphatidylinositol transfer protein PITP{alpha} during axonal extension in hippocampal neurons. Journal of Cell Science, 121(6), 796 - 803. doi:10.1242/jcs.019166
    • Shadan S, Holic R, Carvou N, Ee P, Li M, Murray-Rust J, Cockcroft S (2008). Dynamics of lipid transfer by phosphatidylinositol transfer proteins in cells. Traffic, 9(10), 1743 - 1756. doi:10.1111/j.1600-0854.2008.00794.x
    • Saiardi A, Cockcroft S (2008). Human ITPK1: A Reversible Inositol Phosphate Kinase/Phosphatase That Links Receptor-Dependent Phospholipase C to Ca2+-Activated Chloride Channels. SCI SIGNAL, 1(4), - .
    • Stace C, Manifava M, Delon C, Coadwell J, Cockcroft S, Ktistakis NT (2008). PA binding of phosphatidylinositol 4-phosphate 5-kinase. Advances in Enzyme Regulation, 48(1), 55 - 72. doi:10.1016/j.advenzreg.2007.11.008
    • Saiardi A, Cockcroft S (2008). Human ITPK1: a reversible inositol phosphate kinase/phosphatase that links receptor-dependent phospholipase C to Ca2+-activated chloride channels. Science Signaling, 1(4), pe5 - . doi:10.1126/stke.14pe5

    2007

    • Pedarzani P, Cockcroft S, Challiss RAJ (2007). Compartmentalized signalling in neurones. The Journal of Physiology, 584(2), 371 - 372. doi:10.1113/jphysiol.2007.144766
    • Carvou N, Norden AG, Unwin RJ, Cockcroft S (2007). Signalling through phospholipase C interferes with clathrin-mediated endocytosis. Cellular Signalling, 19(1), 42 - 51.
    • Fensome-Green A, Stannard N, Li M, Bolsover S, Cockcroft S (2007). Bromoenol lactone, an inhibitor of Group V1A calcium-independent phospholipase A(2) inhibits antigen-stimulated mast cell exocytosis without blocking Ca(2+) influx. Cell Calcium, 44, 145 - 153. doi:10.1016/j.ceca.2006.06.002
    • Cockcroft S, Carvou N (2007). Biochemical and biological functions of class I phosphatidylinositol transfer proteins.. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1771(6), 677 - 691. doi:10.1016/j.bbalip.2007.03.009
    • Cockcroft S (2007). Special issue: Lipid transporters in cell biology. BBA-MOL CELL BIOL L, 1771(6), 641 - 643.
    • Cockcroft S (2007). Trafficking of phosphatidylinositol by phosphatidylinositol transfer proteins. Biochemical Society Symposium, 74, 259 - 271.
    • Stace C, Manifava M, Delon C, Coadwell J, Cockcroft S, Ktistakis NT (2007). PA binding of phosphatidylinositol 4-phosphate 5-kinase. Advances in Enzyme Regulation, , - . doi:10.1016/j.advenzreg.2007.11.008

    2006

    • Hyvola N, Diao A, McKenzie E, Skippen A, Cockcroft S, Lowe M (2006). Membrane targeting and activation of the Lowe syndrome protein OCRL1 by rab GTPases. The EMBO Journal, 25(16), 3750 - 3761.
    • Cockcroft S (2006). The latest phospholipase C, PLCeta, is implicated in neuronal function.. Trends in Biochemical Sciences, 31(1), 4 - 7.
    • Fensome-Green A, Cockcroft S (2006). Reconstitution system based on cytosol-depleted cells to study the regulation of phospholipase D.. Methods in Molecular Biology, 332, 299 - 310.
    • Skippen A, Swigart P, Cockcroft S (2006). Measurement of phospholipase C by monitoring inositol phosphates using [3H]inositol-labeling protocols in permeabilized cells.. Methods in Molecular Biology, 312, 183 - 193.
    • Morgan CP, Allen-Baume V, Radulovic M, Li M, Skippen A, Cockcroft S (2006). Differential expression of a C-terminal splice variant of phosphatidylinositol transfer protein beta lacking the constitutive-phosphorylated Ser262 that localizes to the Golgi compartment.. Biochemical Journal, 398(3), 411 - 421. doi:10.1042/BJ20060420

    2005

    • Skippen A, Swigart P, Cockcroft S (2005). Measurement of phospholipase C by monitoring inositol phosphates using [³H]inositol-labeling protocols in permeabilized cells.. Methods Mol Biol, 312, 183 - 193. doi:10.1385/1-59259-949-4:183

    2004

    • Hunt AN, Skippen AJ, Koster G, Postle AD, Cockcroft S (2004). Acyl chain-based molecular selectivity for HL60 cellular phosphatidylinositol and of phosphatidylcholine by phosphatidylinositol transfer protein alpha.. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1686(1-2), 50 - 60. doi:10.1016/j.bbalip.2004.08.003
    • Morgan CP, Skippen A, Segui B, Ball A, Allen-Baume V, Larijani B, Murray-Rust J, McDonald N, Sapkota G, Morrice N, Cockcroft S (2004). Phosphorylation of a distinct structural form of phosphatidylinositol transfer protein alpha at Ser166 by protein kinase C disrupts receptor-mediated phospholipase C signaling by inhibiting delivery of phosphatidylinositol to membranes.. Journal of Biological Chemistry, 279(45), 47159 - 47171. doi:10.1074/jbc.M405827200
    • Tilley SJ, Skippen A, Murray-Rust J, Swigart PM, Stewart A, Morgan CP, Cockcroft S, McDonald NQ (2004). Structure-function analysis of human [corrected] phosphatidylinositol transfer protein alpha bound to phosphatidylinositol.. Structure, 12(2), 317 - 326. doi:10.1016/j.str.2004.04.003
    • Pandey V, Mihara S, Fensome-Green A, Bolsover S, Cockcroft S (2004). Monomeric IgE stimulates NFAT translocation into the nucleus, a rise in cytosol Ca2+, degranulation, and membrane ruffling in the cultured rat basophilic leukemia-2H3 mast cell line.. The Journal of Immunology, 172(7), 4048 - 4058.
    • Tilley SJ, Skippen A, Murray-Rust J, Swigart PM, Stewart A, Morgan CP, Cockcroft S, McDonald NQ (2004). Structure-function analysis of human [corrected] phosphatidylinositol transfer protein alpha bound to phosphatidylinositol.. Structure, 12(2), 317 - 326. doi:10.1016/j.str.2004.01.013
    • Tilley SJ, Skippen A, Murray-Rust J, Swigart PM, Stewart A, Morgan CP, Cockcroft S, McDonald NQ (2004). Structure-function analysis of human phosphatidylinositol transfer protein alpha bound to phosphatidylinositol (vol 12, pg 317, 2004). STRUCTURE, 12(5), 907 - 907.
    • Cockcroft S (2004). Greasy attractions. Nature Cell Biology, 6, 481 - .
    • Morgan CP, Insall R, Haynes L, Cockcroft S (2004). Identification of phospholipase B from Dictyostelium discoideum reveals a new lipase family present in mammals, flies and nematodes, but not yeast.. Biochemical Journal, 382(2), 441 - 449.

    2003

    • Sarri E, Pardo R, Fensome-Green A, Cockcroft S (2003). Endogenous phospholipase D2 localizes to the plasma membrane of RBL-2H3 mast cells and can be distinguished from ADP ribosylation factor-stimulated phospholipase D1 activity by its specific sensitivity to oleic acid.. Biochemical Journal, 369(2), 319 - 329.
    • Carvou NJC, Unwin R, Cockcroft S (2003). Insulin and beta 2-glycoprotein I are endocytosed via different pathways in the kidney proximal tubule.
    • Cockcroft S (2003). Phosphatidylinositol transfer Proteins. In Bradshaw RA, Dennis EA (Ed.), Handbook of Cell Signaling (pp. 225 - 227). : Elsevier.
    • Larijani B, Allen-Baume V, Morgan CP, Li M, Cockcroft S (2003). EGF regulation of PITP dynamics is blocked by inhibitors of phospholipase C and of the Ras-MAP kinase pathway.. Current Biology, 13(1), 78 - 84. doi:10.1016/S0960-9822(02)01395-7

    2002

    • O'Luanaigh N, Pardo R, Fensome A, Allen-Baume V, Jones D, Holt MR, Cockcroft S (2002). Continual production of phosphatidic acid by phospholipase D is essential for antigen-stimulated membrane ruffling in cultured mast cells. Molecular Biology of the Cell, 13(10), 3730 - 3746.
    • Skippen A, Jones DH, Morgan CP, Li M, Cockcroft S (2002). Mechanism of ADP ribosylation factor-stimulated phosphatidylinositol 4,5-bisphosphate synthesis in HL60 cells. Journal of Biological Chemistry, 277(8), 5823 - 5831.
    • Coburn RF, Jones DH, Morgan CP, Baron CB, Cockcroft S (2002). Spermine increases phosphatidylinositol 4,5-bisphosphate content in permeabilized and nonpermeabilized HL60 cells. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1584(1), 20 - 30. doi:10.1016/S1388-1981(02)00265-2
    • Cockcroft S, Way G, O'Luanaigh N, Pardo R, Sarri E, Fensome A (2002). Signalling role for ARF and phospholipase D in mast cell exocytosis stimulated by crosslinking of the high affinity Fc varepsilon R1 receptor. Molecular Immunology, 38(16), 1277 - .
    • Segui B, Allen-Baume V, Cockcroft S (2002). Phosphatidylinositol transfer protein beta displays minimal sphingomyelin transfer activity and is not required for biosynthesis and trafficking of sphingomyelin. Biochemical Journal, 366(1), 23 - 34.
    • Allen-Baume V, Segui B, Cockcroft S (2002). Current thoughts on the phosphatidylinositol transfer protein family. Federation of European Biochemical Societies Letters, 531(1), 74 - 80.
    • Kular GS, Chaudhary A, Prestwich G, Swigart P, Wetzker R, Cockcroft S (2002). Co-operation of phosphatidylinositol transfer protein with phosphoinositide 3-kinase gamma in vitro. Advances in Enzyme Regulation, 42, 53 - 61.

    2001

    • Coburn RF, Jones D, Morgan C, Cockcroft S (2001). A spermine switch augments phosphatidylinositol bisphosphate formation in GTP gamma S-stimulated permeabilized HL60 cells.. FASEB J, 15(4), A527 - A527.
    • Hsuan J, Cockcroft S (2001). The PITP family of phosphatidylinositol transfer proteins.. Genome Biol, 2(9), REVIEWS3011 - .
    • Bolsover S, Ibrahim O, O'luanaigh N, Williams H, Cockcroft S (2001). Use of fluorescent calcium dyes with green fluorescent protein and its variants: problems and solutions . Biochemical Journal, 356(2), 345 - 352.
    • Hsuan J, Cockcroft S (2001). The PITP family of phosphatidylinositol transfer proteins. Genome Biology, 2(9), S3011 - .
    • Cockcroft S, De Matteis MA (2001). Topical review - Inositol lipids as spatial regulators of membrane traffic. J MEMBRANE BIOL, 180(3), 187 - 194.
    • Cockcroft S, Bi K, Ktistakis NT, Roth MG (2001). Biological properties and measurement of phospholipase D activation by ADP-ribosylation factor (ARF). Methods in Enzymology, 329, 355 - 372.
    • Cockcroft S, De Matteis MA (2001). Inositol lipids as spatial regulators of membrane traffic. Journal of Membrane Biology, 180(3), 187 - 194.
    • Cockcroft S (2001). Phosphatidylinositol transfer proteins couple lipid transport to phosphoinositide synthesis. Seminars in Cell and Developmental Biology, 12(2), 183 - 191.
    • Cockcroft S (2001). Signalling roles of mammalian phospholipase D1 and D2. Cellular and Molecular Life Sciences, 58(11), 1674 - 1687.

    2000

    • Cockcroft S (2000). Preface. In Cockcroft S (Ed.), Biology of Phosphoinositides (pp. - ). : Oxford University Press.
    • Jones DH, Morris JB, Morgan CP, Kondo H, Irvine RF, Cockcroft S (2000). Type I phosphatidylinositol 4-phosphate 5-kinase directly interacts with ADP-ribosylation factor 1 and is responsible for phosphatidylinositol 4,5-bisphosphate synthesis in the golgi compartment. Journal of Biological Chemistry, 275(18), 13962 - 13966.
    • Swigart P, Insall R, Wilkins A, Cockcroft S (2000). Purification and cloning of phosphatidylinositol transfer proteins from Dictyostelium discoideum: homologues of both mammalian PITPs and Saccharomyces cerevisiae sec14p are found in the same cell . Biochemical Journal, 347(3), 837 - 843.
    • Way G, O'luanaigh N, Cockcroft S (2000). Activation of exocytosis by cross-linking of the IgE receptor is dependent on ADP-ribosylation factor 1-regulated phospholipase D in RBL- 2H3 mast cells: evidence that the mechanism of activation is via regulation of phosphatidylinositol 4,5-bisphosphate synthesis. Biochemical Journal, 346(1), 63 - 70.

    1999

    • Jones D, Bax B, Cockcroft S (1999). ADP-ribosylation factor GTPases in signal transduction and membrane traffic: Independent functions?. Biochemical Society Transactions, 27, 642 - 647.
    • Jones DH, Bax B, Fensome A, Cockcroft S (1999). ADP ribosylation factor 1 mutants identify a phospholipase D effector region and reveal that phospholipase D participates in lysosomal secretion but is not sufficient for recruitment of coatomer I. Biochemical Journal, 341, 185 - 192.
    • Jones DH, Morgan C, Cockcroft S (1999). Phospholipase D and membrane traffic: potential roles in regulated exocytosis, membrane delivery and vesicle budding. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1439, 229 - 244.
    • Phillips SE, Sha B, Topalof L, Xie Z, Alb JG, Klenchin VA, Swigart P, Cockcroft S, Martin TFJ, Luo M, Bankaitis VA (1999). Yeast Sec14p deficient in phosphatidylinositol transfer activity is functional in vivo. Molecular Cell, 4, 187 - 197.
    • Swigart P, Cockcroft S (1999). Measurement of inositol (poly)phosphate formation using [3H]inositol labeling protocols in permeabilized cells.. Methods Mol Biol, 114, 165 - 173. doi:10.1385/1-59259-250-3:165
    • Ashmore JF, Bolsover SR, Cockcroft S, Duchen MR, Koffer A, Moss SE, Swann K (1999). Imaging as applied to cell signalling: work from the Physiology Imaging Consortium (UCL.PIC).
    • Whatmore J, Wiedemann C, Somerharju P, Swigart P, Cockcroft S (1999). Resynthesis of phosphatidylinositol in permeabilised neutrophils following phospholipase Cá activation: Transport of the intermediate, phosphatidic acid from the plasma membrane to the endoplasmic reticulum for phosphatidylinositol resynthesis is not dependent on soluble lipid carriers or vesicular transport. Biochemical Journal, 341, 435 - 444.
    • Leino L, Forbes L, Segal A, Cockcroft S (1999). Reconstitution of GTPgammaS-induced NADPH oxidase activity in streptolysin-O permeabilised neutrophils by specific cytosol fractions. Biochemical and Biophysical Research Communications, 265, 29 - 37.
    • Cockcroft S (1999). Mammalian phosphatidylinositol transfer proteins: emerging roles in signal transduction and vesicular traffic. Chemistry and Physics of Lipids, 98, 23 - 33.
    • Cockcroft S (1999). Regulatory roles of phosphatidylinositol (4,5)bisphosphate in cell signalling, membrane traffic and the cytoskeleton. In Gordon S (Ed.), Phagocytosis: The Host (pp. 233 - 263). : JAI Press Inc.
    • Ibrahim OH, Bolsover SR, Cockcroft S (1999). Simultaneous measurement of cytosolic calcium and EGFP-PITPα expression in continuous cultures of rat basophilic leukaemia cells.
    • Jones D, Morgan C, Cockcroft S (1999). ARF-regulated phospholipase D in membrane traffic. In Thiery JP (Ed.), Molecular mechanisms of transcellular signalling (pp. 85 - 108). : IOS Press.

    1998

    • Norman JC, Jones D, Holt MR, Barry ST, Cockcroft S, Critchley DR (1998). ARF1 mediates paxillin recruitment to focal adhesions and potentiates rho-stimulated stress fibre formation in intact and permeabilised Swiss 3T3 fibroblasts.. MOL BIOL CELL, 9, 285A - 285A.
    • Wiedemann C, Cockcroft S (1998). The role of phosphatidylinositol transfer proteins (PITPs) in intracellular signalling. Trends in Endocrinology and Metabolism, 9, 324 - 328.
    • Cockcroft S, Leino L, Segal AW (1998). Reconstitution of G-protein-activated NADPH oxidase activity with a cytosolic factor in streptolysin O-permeabilized human neutrophils.
    • Cockcroft S (1998). Phosphatidylinositol transfer proteins: a requirement in signal transduction and vesicle traffic. Bioessays, 20, 423 - 432.
    • Fensome A, Whatmore J, Morgan CP, Jones D, Cockcroft S (1998). ADP ribosylation factor and rho proteins mediate fMLP-dependent activation of phospholipase D in human neurophils. Journal of Biological Chemistry, 273, 13157 - 13164.
    • Wiedemann C, Cockcroft S (1998). Vesicular transport. Sticky fingers grab a lipid.. Nature, 394(6692), 426 - 427. doi:10.1038/28750
    • Wiedemann C, Cockcroft S (1998). Sticky fingers grab a lipid. Nature, 394, 426 - 427.
    • Norman JC, Jones D, Holt MR, Barry ST, Cockcroft S, Critchley DR (1998). ARF1 mediates paxillin recruitment to focal adhesions and potentiates rho-stimulated stress fiber formation in intact and permeabilised Swiss 3T3 fibroblasts. The Journal of Cell Biology, 143, 1981 - 1995.
    • Cockcroft S (1998). Reconstitution system based on cytosol-depleted cells to study the regulation of phospholipases C and D.. Methods Mol Biol, 84, 185 - 197. doi:10.1385/0-89603-488-7:185

    1997

    • Cockcroft S (1997). Phospholipase D: regulation by GTPases and protein kinase C and physiological relevance. Progress in Lipid Research, 35(4), 345 - 370.
    • Cockcroft S, Ball A, Fensome A, Hara S, Jones D, Prosser S, Swigart P (1997). Phosphatidylinositol transfer proteins: an essential requirement in inositol lipid signallling. BIOCHEM SOC TRANS, 1125, 1125 - 1131.
    • Morgan CP, Sengelov H, Whatmore J, Borregaard N, Cockcroft S (1997). ADP-ribosylation-factor-regulated phospholipase D activity localizes to secretory vesicles and mobilizes to the plasma membrane following N-formylmethionyl-leucyl-phenylalanine stimulation of human neutrophils.. Biochem J, 325 ( Pt 3), 581 - 585.
    • Hara S, Swigart P, Jones D, Cockcroft S (1997). The first 5 amino acids of the carboxy terminus of phosphatidylinositol transfer protein à (PITPà) play a critical role in inositol lipid signalling:transfer activity of PITP is essential but not sufficient for restoration of phospholipase C signalling. Journal of Biological Chemistry, 272, 14909 - 14913.
    • Panaretou C, Domin J, Cockcroft S, Waterfield MD (1997). Characterization of p150, an adaptor protein for the human phosphatidylinositol (PtdIns) 3-kinase. Substrate presentation by phosphatidylinositol transfer protein to the p150-PtdIns 3-kinase complex. Journal of Biological Chemistry, 272, 2477 - 2485.
    • Prosser S, Sarra R, Swigart P, Ball A, Cockcroft S (1997). Deletion of 24 amino acids from the C-terminus of phosphatidylinositol transfer protein caues a loss of phospholipase C-mediated inositol lipid signalling. Biochemical Journal, 324, 19 - 23.
    • Allen V, Swigart P, Cheung R, Cockcroft S, Katan M (1997). Regulation of inositol lipid-specific phospholipase Cδ changes in Ca2 ion concentrations. Biochemical Journal, 327, 545 - 552.
    • Hara S, Swigart P, Jones D, Cockcroft S (1997). The first 5 amino acids of the carboxyl terminus of phosphatidylinositol transfer protein (PITP) alpha play a critical role in inositol lipid signaling. Transfer activity of PITP is essential but not sufficient for restoration of phospholipase C signaling.. J Biol Chem, 272(23), 14908 - 14913.
    • Panaretou C, Domin J, Cockcroft S, Waterfield MD (1997). Characterization of p150 an Adaptor Protein for the Human Phosphatidylinositol (PtdIns) 3-Kinase. Journal of Biological Chemistry, 272(4), 2477 - 2485.
    • Kular G, Loubtchenkov M, Swigart P, Whatmore J, Ball A, Cockcroft S, Wetzker R (1997). Co-operation of phosphatidylinositol transfer protein with phosphoinositide 3-kinase (gamma) in the formylmethionyl-leucylphenylamine-dependent production of phosphatidylinositide 3, 4,5, trisphosphate in human neurtrophils. Biochemical Journal, 325, 299 - 301.
    • Morgan CP, Whatmore J, Cockcroft S (1997). Subcellular localization of ARF1-regulated phospholipase D activity in HL60 cells. In Wirtz KW (Ed.), Molecular Mechanisms of Signalling and Membrane Transport (pp. 99 - 112). : Springer.
    • Morgan CP, Sengelov H, Whatmore J, Borregaard N, Cockcroft S (1997). ARF-regulated phospholipase D activity localizes to secretory vesicles and mobilizes to the plasma membrane following fMetLeuPhe stimulation of human neutrophils. Biochemical Journal, 325, 581 - 585.
    • Cockcroft S (1997). Phospatidylionositol transfer proteins: Requirements in phospholipase C signalling and in regulated exocytosis. FEBS LETT, 410, 44 - 48.
    • Allen V, Swigart P, Cheung R, Cockcroft S, Katan M (1997). Regulation of inositol lipid-specific phospholipase cdelta by changes in Ca2+ ion concentrations.. Biochem J, 327 ( Pt 2), 545 - 552.

    1996

    • Vinggaard AM, Jensen T, Morgan CP, Cockcroft S, Hansen HS (1996). Didecanoyl phosphatidylcholine is a superior substrate for assaying mammalian phospholipase D.. Biochem J, 319 ( Pt 3), 861 - 864.
    • Fensome A, Cunningham E, Prosser S, Tan SK, Swigart P, Thomas G, Hsuan J, Cockcroft S (1996). ARF and PITP restore GTP gamma S-stimulated protein secretion from cytosol-depleted HL60 cells by promoting PIP2 synthesis. Current Biology, 6(6), 730 - 738.
    • Cockcroft S (1996). Phospholipid signaling in leukocytes.. Curr Opin Hematol, 3(1), 48 - 54.
    • Cunningham E, Tan SK, Swigart P, Hsuan J, Bankaitis V, Cockcroft S (1996). The yeast and mammalian isoforms of phosphatidylinositol transfer protein can all restore phospholipase C-mediated inositol lipid signaling in cytosol-depleted RBL-2H3 and HL-60 cells. Proceedings of the National Academy of Sciences of the United States of America, 93(13), 6589 - 6593.
    • Cockcroft S (1996). ARF-regulated phospholipase D: a potential role in membrane traffic.. Chem Phys Lipids, 80(1-2), 59 - 80.
    • Whatmore J, Morgan CP, Cunningham E, Collison KS, Willison KR, Cockcroft S (1996). ADP-ribosylation factor 1-regulated phospholipase D activity is localized at the plasma membrane and intracellular organelles in HL60 cells.. Biochem J, 320 ( Pt 3), 785 - 794.

    1995

    • Greasley SE, Jhoti H, Teahan C, Solari R, Fensome A, Thomas GM, Cockcroft S, Bax B (1995). The structure of rat ADP-ribosylation factor-1 (ARF-1) complexed to GDP determined from two different crystal forms.. Nat Struct Biol, 2(9), 797 - 806.
    • de Vries KJ, Heinrichs AA, Cunningham E, Brunink F, Westerman J, Somerharju PJ, Cockcroft S, Wirtz KW, Snoek GT (1995). An isoform of the phosphatidylinositol-transfer protein transfers sphingomyelin and is associated with the Golgi system.. Biochem J, 310 ( Pt 2), 643 - 649.
    • Kauffmann-Zeh A, Thomas GM, Ball A, Prosser S, Cunningham E, Cockcroft S, Hsuan JJ (1995). Requirement for phosphatidylinositol transfer protein in epidermal growth factor signaling. Science, 268(5214), 1188 - 1190.
    • Cunningham E, Thomas GM, Ball A, Hiles I, Cockcroft S (1995). Phosphatidylinositol transfer protein dictates the rate of inositol trisphosphate production by promoting the synthesis of PIP2.. Curr Biol, 5(7), 775 - 783.

    1994

    • THOMAS G, CUNNINGHAM E, BALL A, FENSOME A, COCKCROFT S (1994). AN ESSENTIAL ROLE FOR PHOSPHATIDYLINOSITOL TRANSFER PROTEIN IN INOSITOL LIPID SIGNALING. J CELL BIOCHEM, , 53 - 53.
    • Cockcroft S, Thomas GM, Cunningham E, Ball A (1994). Use of cytosol-depleted HL-60 cells for reconstitution studies of G-protein-regulated phosphoinositide-specific phospholipase C-beta isozymes.. Methods Enzymol, 238, 154 - 168.
    • Cockcroft S, Thomas GM, Fensome A, Geny B, Cunningham E, Gout I, Hiles I, Totty NF, Truong O, Hsuan JJ (1994). Phospholipase D: a downstream effector of ARF in granulocytes.. Science, 263(5146), 523 - 526.
    • Fensome A, Cunningham E, Troung O, Cockcroft S (1994). ARF1(2-17) does not specifically interact with ARF1-dependent pathways. Inhibition by peptide of phospholipases C beta, D and exocytosis in HL60 cells.. FEBS Lett, 349(1), 34 - 38.
    • Thomas GM, Cunningham E, Cockcroft S (1994). Purification of phosphatidylinositol transfer protein from brain cytosol for reconstituting G-protein-regulated phosphoinositide-specific phospholipase C-beta isozymes.. Methods Enzymol, 238, 168 - 181.
    • Whatmore J, Cronin P, Cockcroft S (1994). ARF1-regulated phospholipase D in human neutrophils is enhanced by PMA and MgATP.. FEBS Lett, 352(2), 113 - 117.
    • Greasley S, Jhoti H, Fensome AC, Cockcroft S, Thomas GM, Bax B (1994). Crystallization and preliminary X-ray diffraction studies on ADP-ribosylation factor 1.. J Mol Biol, 244(5), 651 - 653. doi:10.1006/jmbi.1994.1759
    • THOMAS G, FENSOME A, WHATMORE J, GENY B, COCKCROFT S (1994). THE REGULATION OP PHOSPHOLIPASE-D BY ARFS. J NEUROCHEM, 63, S29 - S29.

    1993

    • Thomas GM, Cunningham E, Fensome A, Ball A, Totty NF, Truong O, Hsuan JJ, Cockcroft S (1993). An essential role for phosphatidylinositol transfer protein in phospholipase C-mediated inositol lipid signaling.. Cell, 74(5), 919 - 928.
    • Stutchfield J, Cockcroft S (1993). Correlation between secretion and phospholipase D activation in differentiated HL60 cells.. Biochem J, 293 ( Pt 3), 649 - 655.
    • Geny B, Fensome A, Cockcroft S (1993). Rat brain cytosol contains a factor which reconstitutes guanine-nucleotide-binding-protein-regulated phospholipase-D activation in HL60 cells previously permeabilized with streptolysin O.. Eur J Biochem, 215(2), 389 - 396.

    1992

    • COCKCROFT S (1992). G-PROTEIN-REGULATED PHOSPHOLIPASE-C, PHOSPHOLIPASE-D AND PHOSPHOLIPASE-A(2)-MEDIATED SIGNALING IN NEUTROPHILS. BIOCHIM BIOPHYS ACTA, 1113(2), 135 - 160.
    • Cockcroft S, Thomas GM (1992). Inositol-lipid-specific phospholipase C isoenzymes and their differential regulation by receptors.. Biochem J, 288 ( Pt 1), 1 - 14.
    • Cockcroft S (1992). G-protein-regulated phospholipases C, D and A2-mediated signalling in neutrophils.. Biochim Biophys Acta, 1113(2), 135 - 160.
    • Geny B, Cockcroft S (1992). Synergistic activation of phospholipase D by protein kinase C- and G-protein-mediated pathways in streptolysin O-permeabilized HL60 cells.. Biochem J, 284 ( Pt 2), 531 - 538.

    1991

    • Cockcroft S, Geny B, Thomas GM (1991). Regulation of cytosolic phosphoinositide-phospholipase C by G-protein, Gp.. Biochem Soc Trans, 19(2), 299 - 302.
    • Thomas GM, Geny B, Cockcroft S (1991). Identification of a novel cytosolic poly-phosphoinositide-specific phospholipase C (PLC-86) as the major G-protein-regulated enzyme.. EMBO J, 10(9), 2507 - 2512.
    • Nielson CP, Stutchfield J, Cockcroft S (1991). Chemotactic peptide stimulation of arachidonic acid release in HL60 cells, an interaction between G protein and phospholipase C mediated signal transduction.. Biochim Biophys Acta, 1095(1), 83 - 89.
    • Stutchfield J, Cockcroft S (1991). Characterization of fMet-Leu-Phe-stimulated phospholipase C in streptolysin-O-permeabilised cells.. Eur J Biochem, 197(1), 119 - 125.
    • COCKCROFT S (1991). REQUIREMENT FOR PHOSPHOLIPASE-C AND PHOSPHOLIPASE-A2 ACTIVATION FOR FMETLEUPHE-STIMULATED SECRETION IN STREPTOLYSIN-O-PERMEABILIZED NEUTROPHILS AND HL-60 CELLS.
    • Geny B, Cost H, Barreau P, Basset M, Le Peuch C, Abita JP, Cockcroft S (1991). The differentiating agent, retinoic acid, causes an early inhibition of inositol lipid-specific phospholipase C activity in HL-60 cells.. Cell Signal, 3(1), 11 - 23.
    • Marvel J, Rimon G, Tatham P, Cockcroft S (1991). Evidence that the CD45 phosphatase regulates the activity of the phospholipase C in mouse T lymphocytes.. Eur J Immunol, 21(1), 195 - 201. doi:10.1002/eji.1830210129
    • Cockcroft S (1991). Relationship between arachidonate release and exocytosis in permeabilized human neutrophils stimulated with formylmethionyl-leucyl-phenylalanine (fMetLeuPhe), guanosine 5'-[gamma-thio]triphosphate (GTP[S]) and Ca2+.. Biochem J, 275 ( Pt 1), 127 - 131.
    • Cockcroft S, Nielson CP, Stutchfield J (1991). Is phospholipase A2 activation regulated by G-proteins?. Biochem Soc Trans, 19(2), 333 - 336.

    1990

    • Cockcroft S, Bar-Sagi D (1990). Effect of H-ras proteins on the activity of polyphosphoinositide phospholipase C in HL60 membranes.. Cell Signal, 2(3), 227 - 234.
    • Cockcroft S (1990). G-proteins and exocytotic secretion in phagocytic cells.. FEMS Microbiol Immunol, 2(1), 3 - 8.
    • Stutchfield J, Cockcroft S (1990). Undifferentiated HL60 cells respond to extracellular ATP and UTP by stimulating phospholipase C activation and exocytosis.. FEBS Lett, 262(2), 256 - 258.

    1989

    • Cockcroft S, Stutchfield J (1989). The receptors for ATP and fMetLeuPhe are independently coupled to phospholipases C and A2 via G-protein(s). Relationship between phospholipase C and A2 activation and exocytosis in HL60 cells and human neutrophils.. Biochem J, 263(3), 715 - 723.
    • Geny B, Stutchfield J, Cockcroft S (1989). Phorbol ester inhibits polyphosphoinositide phosphodiesterase activity stimulated by either Ca2+, fluoride or GTP analogue in HL60 membranes and in permeabilized HL60 cells.. Cell Signal, 1(2), 165 - 172.
    • Cockcroft S, Stutchfield J (1989). ATP stimulates secretion in human neutrophils and HL60 cells via a pertussis toxin-sensitive guanine nucleotide-binding protein coupled to phospholipase C.. FEBS Lett, 245(1-2), 25 - 29.

    1988

    • Cockcroft S, Stutchfield J (1988). Effect of pertussis toxin and neomycin on G-protein-regulated polyphosphoinositide phosphodiesterase. A comparison between HL60 membranes and permeabilized HL60 cells.. Biochem J, 256(2), 343 - 350.
    • STUTCHFIELD J, COCKCROFT S (1988). EFFECTS OF PHORBOL ESTER ON INOSITOL TRISPHOSPHATE PRODUCTION AND SECRETION IN PERMEABILIZED HL-60 CELLS. BIOCHEM SOC T, 16(6), 994 - 995.
    • Cockcroft S, Stutchfield J (1988). G-proteins, the inositol lipid signalling pathway, and secretion.. Philos Trans R Soc Lond B Biol Sci, 320(1199), 247 - 265.
    • Geny B, LePeuch C, Cost H, Basset M, Cockcroft S (1988). Phorbol esters inhibit inositol phosphate and diacylglycerol formation in proliferating HL60 cells. Relationship to differentiation.. FEBS Lett, 233(2), 239 - 243.
    • Stutchfield J, Cockcroft S (1988). Guanine nucleotides stimulate polyphosphoinositide phosphodiesterase and exocytotic secretion from HL60 cells permeabilized with streptolysin O.. Biochem J, 250(2), 375 - 382.

    1987

    • Field JB, Ealey PA, Marshall NJ, Cockcroft S (1987). Thyroid-stimulating hormone stimulates increases in inositol phosphates as well as cyclic AMP in the FRTL-5 rat thyroid cell line.. Biochem J, 247(3), 519 - 524.
    • Cockcroft S, Lamb JR, Zanders ED (1987). Inositol lipid metabolism in human T lymphocytes activated via the T3 complex.. Immunology, 60(2), 209 - 212.
    • Barrowman MM, Cockcroft S, Gomperts BD (1987). Differential control of azurophilic and specific granule exocytosis in Sendai-virus-permeabilized rabbit neutrophils.. J Physiol, 383, 115 - 124.
    • Gomperts BD, Cockcroft S, Howell TW, Nüsse O, Tatham PE (1987). The dual effector system for exocytosis in mast cells: obligatory requirement for both Ca2+ and GTP.. Biosci Rep, 7(5), 369 - 381.
    • Cockcroft S, Taylor JA (1987). Fluoroaluminates mimic guanosine 5'-[gamma-thio]triphosphate in activating the polyphosphoinositide phosphodiesterase of hepatocyte membranes. Role for the guanine nucleotide regulatory protein Gp in signal transduction.. Biochem J, 241(2), 409 - 414.
    • Cockcroft S, Howell TW, Gomperts BD (1987). Two G-proteins act in series to control stimulus-secretion coupling in mast cells: use of neomycin to distinguish between G-proteins controlling polyphosphoinositide phosphodiesterase and exocytosis.. J Cell Biol, 105(6 Pt 1), 2745 - 2750.
    • COCKCROFT S (1987). POLYPHOSPHOINOSITIDE PHOSPHODIESTERASE - REGULATION BY A NOVEL GUANINE-NUCLEOTIDE BINDING PROTEIN-GP. TRENDS BIOCHEM SCI, 12(2), 75 - 78.
    • Howell TW, Cockcroft S, Gomperts BD (1987). Essential synergy between Ca2+ and guanine nucleotides in exocytotic secretion from permeabilized rat mast cells.. J Cell Biol, 105(1), 191 - 197.
    • Sagi-Eisenberg R, Foreman JC, Raval PJ, Cockcroft S (1987). Protein and diacylglycerol phosphorylation in the stimulus-secretion coupling of rat mast cells.. Immunology, 61(2), 203 - 206.

    1986

    • Cockcroft S (1986). The dependence on Ca2+ of the guanine-nucleotide-activated polyphosphoinositide phosphodiesterase in neutrophil plasma membranes.. Biochem J, 240(2), 503 - 507.
    • Gomperts BD, Barrowman MM, Cockcroft S (1986). Dual role for guanine nucleotides in stimulus-secretion coupling.. Fed Proc, 45(7), 2156 - 2161.
    • Barrowman MM, Cockcroft S, Gomperts BD (1986). Potentiation and inhibition of secretion from neutrophils by phorbol ester.. FEBS Lett, 201(1), 137 - 142.
    • Barrowman MM, Cockcroft S, Gomperts BD (1986). Two roles for guanine nucleotides in the stimulus-secretion sequence of neutrophils.. Nature, 319(6053), 504 - 507. doi:10.1038/319504a0

    1985

    • Cockcroft S, Barrowman MM, Gomperts BD (1985). Breakdown and synthesis of polyphosphoinositides in fMetLeuPhe-stimulated neutrophils.. FEBS Lett, 181(2), 259 - 263.
    • GOMPERTS BD, BARROWMAN MM, COCKCROFT S (1985). GUANINE-NUCLEOTIDES CONTROL POLYPHOSPHOINOSITIDE SPECIFIC PHOSPHODIESTERASE IN RECEPTOR MEDIATED CA-2+ MOBILIZATION IN NEUTROPHILS. FED PROC, 44(3), 780 - 780.
    • Cockcroft S, Gomperts BD (1985). Role of guanine nucleotide binding protein in the activation of polyphosphoinositide phosphodiesterase.. Nature, 314(6011), 534 - 536.
    • Cockcroft S, Taylor JA, Judah JD (1985). Subcellular localisation of inositol lipid kinases in rat liver.. Biochim Biophys Acta, 845(2), 163 - 170.
    • Segal AW, Heyworth PG, Cockcroft S, Barrowman MM (1985). Stimulated neutrophils from patients with autosomal recessive chronic granulomatous disease fail to phosphorylate a Mr-44,000 protein.. Nature, 316(6028), 547 - 549.

    1984

    • Cockcroft S, Allan D (1984). The fatty acid composition of phosphatidylinositol, phosphatidate and 1,2-diacylglycerol in stimulated human neutrophils.. Biochem J, 222(2), 557 - 559.
    • Cockcroft S (1984). Contrasting roles for receptor-stimulated inositol lipid metabolism in secretory cells.. Biochem Soc Trans, 12(6), 966 - 968.
    • Cockcroft S (1984). Ca2+-dependent conversion of phosphatidylinositol to phosphatidate in neutrophils stimulated with fMet-Leu-Phe or ionophore A23187.. Biochim Biophys Acta, 795(1), 37 - 46.
    • Cockcroft S, Baldwin JM, Allan D (1984). The Ca2+-activated polyphosphoinositide phosphodiesterase of human and rabbit neutrophil membranes.. Biochem J, 221(2), 477 - 482.

    1983

    • Allan D, Cockcroft S (1983). The fatty acid composition of 1,2-diacylglycerol and polyphosphoinositides from human erythrocyte membranes.. Biochem J, 213(2), 555 - 557.

    1982

    • Cockcroft S (1982). Phosphatidylinositol metabolism in mast cells and neutrophils.. Cell Calcium, 3(4-5), 337 - 349.
    • COCKCROFT S (1982). A MECHANISM FOR MUSCARINIC INHIBITION OF CAMP ACCUMULATION - POSSIBLE ROLE FOR PHOSPHATIDYLINOSITOL HYDROLYSIS. TRENDS PHARMACOL SCI, 3(4), 139 - 139.
    • Bennett JP, Cockcroft S, Caswell AH, Gomperts BD (1982). Plasma-membrane location of phosphatidylinositol hydrolysis in rabbit neutrophils stimulated with formylmethionyl-leucylphenylalanine.. Biochem J, 208(3), 801 - 808.
    • Allan D, Cockcroft S (1982). A modified procedure for thin-layer chromatography of phospholipids.. J Lipid Res, 23(9), 1373 - 1374.

    1981

    • COCKCROFT S (1981). DOES PHOSPHATIDYLINOSITOL BREAKDOWN CONTROL THE CA-2+-GATING MECHANISM. TRENDS PHARMACOL SCI, 2(12), 340 - 342.
    • Bennett JP, Cockcroft S, Gomperts BD (1981). Rat mast cells permeabilized with ATP secrete histamine in response to calcium ions buffered in the micromolar range.. J Physiol, 317, 335 - 345.
    • Cockcroft S, Bennett JP, Gomperts BD (1981). The dependence on Ca2+ of phosphatidylinositol breakdown and enzyme secretion in rabbit neutrophils stimulated by formylmethionyl-leucylphenylalanine or ionomycin.. Biochem J, 200(3), 501 - 508.

    1980

    • Cockcroft S, Bennett JP, Gomperts BD (1980). f-MetLeuPhe-induced phosphatidylinositol turnover in rabbit neutrophils is dependent on extracellular calcium.. FEBS Lett, 110(1), 115 - 118.
    • COCKCROFT S, JONES LM, ALLAN D, MICHELL RH (1980). EFFECTS OF ALKYLATING ANTAGONISTS ON THE STIMULATED TURNOVER OF PHOSPHATIDYLINOSITOL PRODUCED BY A VARIETY OF CALCIUM-MOBILIZING RECEPTOR SYSTEMS. CELL CALCIUM, 1(1), 49 - 68.
    • Cockcroft S, Gomperts BD (1980). The ATP4- receptor of rat mast cells.. Biochem J, 188(3), 789 - 798.
    • Gomperts BD, Cockcroft S, Bennett JP, Fewtrell CM (1980). Early events in the activation of Ca2+ dependent secretion: studies with rat peritoneal mast cells.. J Physiol (Paris), 76(5), 383 - 393.
    • Bennett JP, Cockcroft S, Gomperts BD (1980). Use of cytochalasin B to distinguish between early and late events in neutrophil activation.. Biochim Biophys Acta, 601(3), 584 - 591.
    • Cockcroft S, Bennett JP, Gomperts BD (1980). Stimulus-secretion coupling in rabbit neutrophils is not mediated by phosphatidylinositol breakdown.. Nature, 288(5788), 275 - 277.

    1979

    • Cockcroft S, Gomperts BD (1979). Evidence for a role of phosphatidylinositol turnover in stimulus-secretion coupling. Studies with rat peritoneal mast cells.. Biochem J, 178(3), 681 - 687.
    • Cockcroft S, Gomperts BD (1979). ATP induces nucleotide permeability in rat mast cells.. Nature, 279(5713), 541 - 542.
    • Jones LM, Cockcroft S, Michell RH (1979). Stimulation of phosphatidylinositol turnover in various tissues by cholinergic and adrenergic agonists, by histamine and by caerulein.. Biochem J, 182(3), 669 - 676.
    • Cockcroft S, Gomperts BD (1979). Activation and inhibition of calcium-dependent histamine secretion by ATP ions applied to rat mast cells.. J Physiol, 296, 229 - 243.
    • Bennett JP, Cockcroft S, Gomperts BD (1979). Ionomycin stimulates mast cell histamine secretion by forming a lipid-soluble calcium complex.. Nature, 282(5741), 851 - 853.

    1977

    • Michell RH, Jafferji SS, Jones LM (1977). The possible involvement of phosphatidylinositol breakdown in the mechanism of stimulus-response coupling at receptors which control cell-surface calcium gates.. Adv Exp Med Biol, 83, 447 - 464.
    • Jafferji SS, Michell RH (1977). The relationship between calcium ion gates and the stimulation of phosphatidylinositol turnover.. Biochem Soc Trans, 5(1), 104 - 106.
    • Michell RH, Jones LM, Jafferji SS (1977). A possible role for phosphatidylinositol breakdown in muscarinic cholinergic stimulus-response coupling.. Biochem Soc Trans, 5(1), 77 - 81.

    1976

    • Michell RH, Jafferji SS, Jones LM (1976). Receptor occupancy dose--response curve suggests that phosphatidyl-inositol breakdown may be intrinsic to the mechanism of the muscarinic cholinergic receptor.. FEBS Lett, 69(1), 1 - 5.
    • Jafferji SS, Michell RH (1976). Effects of calcium-antagonistic drugs on the stimulation by carbamoylcholine and histamine of phosphatidylinositol turnover in longitudinal smooth muscle of guinea-pig ileum.. Biochem J, 160(2), 163 - 169.
    • Jafferji SS, Michell RH (1976). Investigation of the relationship between cell-surface calcium-ion gating and phosphatidylinositol turnover by comparison of the effects of elevated extracellular potassium ion concentration on ileium smooth muscle and pancreas.. Biochem J, 160(2), 397 - 399.
    • Jafferji SS, Michell RH (1976). Stimulation of phosphatidylinositol turnover by histamine, 5-hydroxytryptamine and adrenaline in the longitudinal smooth muscle of guinea pig ileum.. Biochem Pharmacol, 25(12), 1429 - 1430.
    • Jafferji SS, Michell RH (1976). Muscarinic cholinergic stimulation of phosphatidylinositol turnover in the longitudinal smooth muscle of guinea-pig ileum.. Biochem J, 154(3), 653 - 657.