Dr Vehid Salih

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Personal Profile

Name: Vehid Salih Email: v.salih@ucl.ac.uk
Title: Dr Tel: 0203 456 1133
Department: Biomaterials & Tissue Eng Fax:
Position: Senior Lecturer Address: BTE Division, UCL Eastman Dental Institute, 256 Gray's Inn Road, London, WC1X 8LD
Research Domain: Basic Life Sciences Web Page: Personal Web Page

Profile

Research Description

Early projects investigated the interaction of osteoblast cells with novel soluble glasses and led to the development of a transformed human bone cell line originating from alveolar bone using viral transduction techniques. Subsequent work has been performed in collaboration with the Periodontology Deptartment, carrying out extensive studies of the biological response to novel bioceramic materials developed in the BTE Division. This work focussed on the effects of these glasses on a variety of soft and hard connective tissue cells, particularly at the gene level. VS has also been involved in preliminary studies of the interaction of cells with novel glass fibres and has investigated the effects of these fibres on the growth of human ligament in vitro using real-time imaging. The development of novel biomaterials and subsequent in vivo studies will lead to exploitation by established orthopaedic centres or biotechnology companies. Further funded studies involve the effects of therapeutic ultrasound on the in vitro growth and function of soft and hard connective tissue cells. More recently, new research work has involved the expression and processing of cell receptors, in particular of bone morphogenetic proteins, within oral tissues. VS also collaborates with clinical colleagues investigating methods of improving surgical repair in Periodontology using novel tissue regeneration techniques and in Oral Surgery developing novel photodynamic therapies for detection and treatment of oral cancers. More recent funded projects include the in vitro and in vivo characterisation of novel bone cements and adhesives for a variety of tissue regeneration applications.

Research Activities

Biocompatibility

Cell/Biomaterial interactions

Characterisation of stem cell treated osteogenesis imperfect with AFM analysis.

Characterisation of tissue engineered constructs

Development of new injectable, PolyGeneCaP composites for gene therapy

Development of standardised culture protocols

Injectable drug - releasing composites for tooth a

Raman spectral analysis and bioactive glasses

Re-mineralising, antibacterial composites and adhesives for more durable, conservative and pain less tooth restoration

Education Description

Programme Director for the Diploma in Clinical Dental Science Teaching activities involve supervision of several PhD and MSc students from within UCL as well as external universities Course lecturer on CPD course "Restorative Dentistry in Sports"; Common Core course; MSc Biomaterials/Tissue Engineering

UCL Collaborators

Dr Jonathan Pratten; Dr Dave Spratt; Dr Anne Young; Dr Paul Ashley; Dr Gavin Jell; Dr Laurent Bozec; Prof Irwin Olsen

External Collaborators

Publications

    2013

    • Lakhkar NJ, Lee IH, Kim HW, Salih V, Wall IB, Knowles JC (2013). Bone formation controlled by biologically relevant inorganic ions: Role and controlled delivery from phosphate-based glasses.. Adv Drug Deliv Rev, 65(4), 405 - 420. doi:10.1016/j.addr.2012.05.015
    • Yunos DM, Ahmad Z, Salih V, Boccaccini AR (2013). Stratified scaffolds for osteochondral tissue engineering applications: electrospun PDLLA nanofibre coated Bioglass®-derived foams.. J Biomater Appl, 27(5), 537 - 551. doi:10.1177/0885328211414941

    2012

    • Neel EAA, Salih V, Revell PA, Young AM (2012). Viscoelastic and biological performance of low-modulus, reactive calcium phosphate-filled, degradable, polymeric bone adhesives. Acta Biomaterialia, 8(1), 313 - 320.
    • Khan MR, Donos N, Salih V, Brett PM (2012). The enhanced modulation of key bone matrix components by modified Titanium implant surfaces.. Bone, 50(1), 1 - 8. doi:10.1016/j.bone.2011.07.040
    • Chatzistavrou X, Tsigkou O, Amin HD, Paraskevopoulos KM, Salih V, Boccaccini AR (2012). Sol-gel based fabrication and characterization of new bioactive glass-ceramic composites for dental applications. Journal of the European Ceramic Society, 32(12), 3051 - 3061.
    • Bretcanu O, Boccaccini AR, Salih V (2012). Poly-DL-lactic acid coated Bioglass® scaffolds: Toughening effects and osteosarcoma cell proliferation. Journal of Materials Science, 47(15), 5661 - 5672.
    • Lakhkar NJ, Park JH, Mordan NJ, Salih V, Wall IB, Kim HW, King SP, Hanna JV, Martin RA, Addison O, Mosselmans JFW, Knowles JC (2012). Titanium phosphate glass microspheres for bone tissue engineering.
    • Chatzistavrou X, Paraskevopoulos KM, Salih V, Boccaccini AR, Kasuga T (2012). Ag-doped sol-gel derived novel composite materials for dental Applications. Key Engineering Materials, 493-494, 637 - 642.
    • Nooeaid P, Salih V, Beier JP, Boccaccini AR (2012). Osteochondral tissue engineering: scaffolds, stem cells and applications.. J Cell Mol Med, 16(10), 2247 - 2270. doi:10.1111/j.1582-4934.2012.01571.x
    • Kiani A, Lakhkar NJ, Salih V, Smith ME, Hanna JV, Newport RJ, Pickup DM, Knowles JC (2012). Titanium-containing bioactive phosphate glasses.. Philos Trans A Math Phys Eng Sci, 370(1963), 1352 - 1375. doi:10.1098/rsta.2011.0276
    • Abou Neel EA, Salih V, Revell PA, Young AM (2012). Viscoelastic and biological performance of low-modulus, reactive calcium phosphate-filled, degradable, polymeric bone adhesives.. Acta Biomater, 8(1), 313 - 320. doi:10.1016/j.actbio.2011.08.008
    • Kiani A, Hanna JV, King SP, Rees GJ, Smith ME, Roohpour N, Salih V, Knowles JC (2012). Structural characterization and physical properties of P2O5-CaO-Na2O-TiO2 glasses by Fourier transform infrared, Raman and solid-state magic angle spinning nuclear magnetic resonance spectroscopies.. Acta Biomater, 8(1), 333 - 340. doi:10.1016/j.actbio.2011.08.025
    • Kiani A, Hanna JV, King SP, Rees GJ, Smith ME, Roohpour N, Salih V, Knowles JC (2012). Structural characterization and physical properties of P 2O 5-CaO-Na 2O-TiO 2 glasses by Fourier transform infrared, Raman and solid-state magic angle spinning nuclear magnetic resonance spectroscopies. Acta Biomaterialia, 8(1), 333 - 340.
    • Khan MR, Donos N, Salih V, Brett PM (2012). The enhanced modulation of key bone matrix components by modified Titanium implant surfaces. Bone, 50(1), 1 - 8.
    • Lakhkar NJ, Park JH, Mordan NJ, Salih V, Wall IB, Kim HW, King SP, Hanna JV, Martin RA, Addison O, Mosselmans JF, Knowles JC (2012). Titanium phosphate glass microspheres for bone tissue engineering.. Acta biomaterialia, 8(11), 4181 - 4190.

    2011

    • Rai R, Boccaccini AR, Knowles JC, Mordon N, Salih V, Locke IC, Moshrefi-Torbati M, Keshavarz T, Roy I (2011). The Homopolymer Poly(3-hydroxyoctanoate) as a Matrix Material for Soft Tissue Engineering. doi:10.1002/app.34772
    • Meng D, Rath SN, Mordan N, Salih V, Kneser U, Boccaccini AR (2011). In vitro evaluation of 45S5 Bioglass®-derived glass-ceramic scaffolds coated with carbon nanotubes.. J Biomed Mater Res A, 99(3), 435 - 444. doi:10.1002/jbm.a.33185
    • Lakhkar N, Abou Neel EA, Salih V, Knowles JC (2011). Titanium and strontium-doped phosphate glasses as vehicles for strontium ion delivery to cells.. J Biomater Appl, 25(8), 877 - 893. doi:10.1177/0885328210362125
    • Sebbowa T, Edirisinghe M, Salih V, Huang J (2011). Effect of deposition parameters and post-deposition annealing on the morphology and cellular response of electrosprayed TiO2 films.. Biofabrication, 3(4), 045001 - . doi:10.1088/1758-5082/3/4/045001
    • Raison C, Porter S, Fedele S, Lewis MP, Salih V (2011). Collagen gel as a 3D in vitro tissue model for ameloblastoma studies.
    • Raison C, Porter SR, Fedele S, Lewis MP, Salih V (2011). In vitro 3D tissue modelling: Insights into ameloblastoma pathogenesis.
    • Meng D, Rath SN, Mordan N, Salih V, Kneser U, Boccaccini AR (2011). In vitro evaluation of 45S5 Bioglass®-derived glass-ceramic scaffolds coated with carbon nanotubes. Journal of Biomedical Materials Research - Part A, 99 A(3), 435 - 444.

    2010

    • Zhao X, Olsen I, Li H, Gellynck K, Buxton PG, Knowles JC, Salih V, Young AM (2010). Reactive calcium-phosphate-containing poly(ester-co-ether) methacrylate bone adhesives: chemical, mechanical and biological considerations. Acta Biomaterialia, 6(3), 845 - 855.
    • Misra SK, Ansari TI, Valappil SP, Mohn D, Philip SE, Stark WJ, Roy I, Knowles JC, Salih V, Boccaccini AR (2010). Poly(3-hydroxybutyrate) multifunctional composite scaffolds for tissue engineering applications. Biomaterials, 31(10), 2806 - 2815.
    • Misra SK, Ansari TI, Valappil SP, Mohn D, Philip SE, Stark WJ, Roy I, Knowles JC, Salih V, Boccaccini AR (2010). Poly(3-hydroxybutyrate) multifunctional composite scaffolds for tissue engineering applications. Biomaterials, 31(10), 2806 - 2815.
    • Raghunath J, Sutherland J, Salih V, Mordan N, Butler PE, Seifalian AM (2010). Chondrogenic potential of blood-acquired mesenchymal progenitor cells.. J Plast Reconstr Aesthet Surg, 63(5), 841 - 847. doi:10.1016/j.bjps.2009.01.063
    • Abou Neel EA, Palmer G, Knowles JC, Salih V, Young AM (2010). Chemical, modulus and cell attachment studies of reactive calcium phosphate filler-containing fast photo-curing, surface-degrading, polymeric bone adhesives.. Acta Biomater, 6(7), 2695 - 2703. doi:10.1016/j.actbio.2010.01.012
    • Chrzanowski W, Neel EA, Armitage DA, Zhao X, Knowles JC, Salih V (2010). In vitro studies on the influence of surface modification of Ni-Ti alloy on human bone cells.. J Biomed Mater Res A, 93(4), 1596 - 1608. doi:10.1002/jbm.a.32646
    • Misra SK, Ohashi F, Valappil SP, Knowles JC, Roy I, Silva SR, Salih V, Boccaccini AR (2010). Characterization of carbon nanotube (MWCNT) containing P(3HB)/bioactive glass composites for tissue engineering applications.. Acta Biomater, 6(3), 735 - 742. doi:10.1016/j.actbio.2009.09.023
    • Misra SK, Ansari T, Mohn D, Valappil SP, Brunner TJ, Stark WJ, Roy I, Knowles JC, Sibbons PD, Jones EV, Boccaccini AR, Salih V (2010). Effect of nanoparticulate bioactive glass particles on bioactivity and cytocompatibility of poly(3-hydroxybutyrate) composites.. J R Soc Interface, 7(44), 453 - 465. doi:10.1098/rsif.2009.0255
    • Francis L, Meng DC, Locke IC, Mordan N, Salih V, Knowles JC, Boccaccini AR, Roy I (2010). The Influence of Tetracycline Loading on the Surface Morphology and Biocompatibility of Films Made from P(3HB) Microspheres. doi:10.1002/adem.201080020
    • Rai R, Boccaccini AR, Knowles JC, Locke IC, Gordge MP, Mc Cormick A, Salih V, Mordon N, Keshavarz T, Roy I (2010). Fabrication of a novel poly(3-hydroxyoctanoate)/nanoscale bioactive glass composite film with potential as a multifunctional wound dressing.
    • Dashti A, Ready D, Salih V, Knowles JC, Barralet JE, Wilson M, Donos N, Nazhat SN (2010). In vitro antibacterial efficacy of tetracycline hydrochloride adsorbed onto Bio-Oss bone graft.. J Biomed Mater Res B Appl Biomater, 93(2), 394 - 400. doi:10.1002/jbm.b.31594

    2009

    • Mehdawi I, Abou Neel EA, Valappil SP, Palmer G, Salih V, Pratten J, Spratt DA, Young AM (2009). Development of remineralizing, antibacterial dental materials. Acta Biomaterialia, 5(7), 2525 - 2539.
    • Lakhar NJ, Abou Neel EA, Salih V, Knowles JC (2009). Strontium oxide doped quaternary glasses: effect on structure, degradation and cytocompatibility. Journal of Materials Science: Materials in Medicine, 20(6), 1339 - 1346.
    • Alekseeva T, Abou Neel EA, Nazhat S, Bitar M, Knowles JC, Salih V, Brown RA (2009). Plastic Compressed Collagen Reinforced with Phosphate-Based Glass for Bone Tissue Engineering.
    • Bretcanu O, Misra S, Roy I, Renghini C, Fiori F, Boccaccini AR, Salih V (2009). In vitro biocompatibility of 45S5 Bioglass-derived glass-ceramic scaffolds coated with poly(3-hydroxybutyrate).. J Tissue Eng Regen Med, 3(2), 139 - 148. doi:10.1002/term.150
    • Salih V (2009). Biodegradable scaffolds for tissue engineering. In Di Silvio L (Ed.), Cellular Response to Biomaterials (pp. 185 - 211). : Woodhead Publishing Ltd..
    • Bohr A, Memarzadeh K, Alp B, Brown R, Salih V (2009). Single unconfined compression of cellular dense collagen scaffolds for cartilage and bone tissue engineering.
    • Misra SK, Philip SE, Chrzanowski W, Nazhat SN, Roy I, Knowles JC, Salih V, Boccaccini AR (2009). Incorporation of vitamin E in poly(3hydroxybutyrate)/Bioglass composite films: effect on surface properties and cell attachment. Journal of the Royal Society Interface, 6(33), 401 - 409.

    2008

    • Zhao X, Ho SM, Salih V, Young A (2008). Injectable biodegradable reactive calcium phosphate loaded composites for combined bone repair and drug delivery. 8th World Biomaterials Congress 2008, 2, 827 - 827.
    • Misra SK, Mohn D, Brunner TJ, Stark WJ, Philip SE, Roy I, Salih V, Knowles JC, Boccaccini AR (2008). Nano- versus micron-sized bioactive glass reinforcement of P(3HB) - Are nano-fillers the way forward?. 8th World Biomaterials Congress 2008, 2, 863 - 863.
    • Salih V (2008). Bone morphogenetic proteins as therapeutic agents for tissue regeneration. J PHARM PHARMACOL, 60, A71 - A71.
    • Chen QZ, Efthymiou A, Salih V, Boccaccini AR (2008). Bioglass-derived glass-ceramic scaffolds: study of cell proliferation and scaffold degradation in vitro.. J Biomed Mater Res A, 84(4), 1049 - 1060. doi:10.1002/jbm.a.31512
    • Chrzanowski W, Armitage DA, Mordan N, Knowles JC, Salih V (2008). Human cell response on surface-modified nickel titanium alloy (Nitinol). 8th World Biomaterials Congress 2008, 3, 1209 - 1209.
    • Bitar M, Brown RA, Salih V, Kidane AG, Knowles JC, Nazhat SN (2008). Effect of cell density on osteoblastic differentiation and matrix degradation of biomimetic dense collagen scaffolds. Biomacromolecules, 9(1), 129 - 135.
    • Misra SK, Mohn D, Brunner TJ, Stark WJ, Philip SE, Roy I, Salih V, Knowles JC, Boccaccini AR (2008). Comparison of nanoscale and microscale bioactive glass on the properties of P(3HB)/Bioglass® composites. Biomaterials, 29(12), 1750 - 1761.
    • Hakim W, Smith A, Kazmi B, Kalmann B, Solomon A, Salih V, Greensmith L, Mudera V, Lewis MP (2008). Muscle-nerve interactions in chimaeric in vitro 3D collagen models.
    • Abou Neel EA, Zhao X, Ho SM, Knowles JC, Salih V, Young AM (2008). Injectable degradable polymeric adhesives containing reactive calcium phosphate filler particles.
    • Singhatanadgit W, Salih V, Olsen I (2008). RNA interference of the BMPR-IB gene blocks BMP-2-induced osteogenic gene expression in human bone cells. Cell Biology International, 32(11), 1362 - 1370.
    • Singhatanadgit W, Mordan NJ, Salih V, Olsen I (2008). Changes in bone morphogenetic protein receptor-IB localisation regulate osteogenic responses of human bone cells to bone morphogenetic protein-2. The International Journal of Biochemistry and Cell Biology, 40(12), 2854 - 2864.
    • Bitar M, Salih V, Knowles JC, Lewis MP (2008). Iron-phosphate glass fiber scaffolds for the hard-soft interface regeneration: the effect of fiber diameter and flow culture condition on cell survival and differentiation. Journal of Biomedical Materials Research Part A, 87(4), 1017 - 1026.
    • Bretcanu O, Misra SK, Roy I, Salih V, Hellmich C, Boccaccini AR (2008). Optimisation of bioglass®-derived scaffolds for bone tissue engineering. 8th World Biomaterials Congress 2008, 3, 1262 - 1262.

    2007

    • Singhatanadgit W, Salih V, Olsen I (2007). Up-regulation of bone morphogenetic protein receptor (BMPR) genes by orthopaedic and dental implant materials.
    • Salih V, Patel A, Knowles JC (2007). Zinc-containing phosphate-based glasses for tissue engineering.. Biomed Mater, 2(1), 11 - 20. doi:10.1088/1748-6041/2/1/003
    • Salih V, Patel A, Knowles JC (2007). Zinc-containing phosphate-based glasses for tissue engineering. Biomedical Materials, 2(1), 11 - 20.
    • Abou Neel EA, Mizoguchi T, Ito M, Bitar M, Salih V, Knowles JC (2007). In vitro bioactivity and gene expression by cells cultured on titanium dioxide doped phosphate-based glasses. Biomaterials, 28(19), 2967 - 2977.
    • Bitar M, Salih V, Brown RA, Nazhat SN (2007). Effect of multiple unconfined compression on cellular dense collagen scaffolds for bone tissue engineering. Journal of Materials Science: Materials in Medicine, 18(2), 237 - 244.
    • Hakim W, Solomon A, Salih V, Mudera V, Lewis MP (2007). Muscle-nerve interactions in an in vitro 3D collagen gel model.

    2006

    • Salih V, Prendergast P (2006). Discussion with reviewers. EUR CELLS MATER, 11, 75 - 75.
    • Jerjes W, Sharwani A, Salih V, Hopper C (2006). Fluorescence spectroscopy combined with 5-ALA induced PpIX fluorescence in detecting oral leukoplakia.
    • Jerjes W, Sharwani A, Hopper C, El-Maaytah M, Salih V (2006). Epidermal growth factor receptor-tyrosine kinase inhibitors augment photodynamic therapy-antitumour activity and down-regulate in vitro invasion.
    • Salih V, Mordan NJ, Abou Neel EA, Armitage DA, Jones FH, Knowles JC, Nazhat SN, Vargas-Coronado R, Cauich-Rodriguez JV (2006). Surface characterisation of various bone cements prepared with functionalised methacrylates/bioactive ceramics in relation to HOB behaviour. Acta Biomaterialia, 2(2), 143 - 154. doi:10.1016/j.actbio.2005.12.001
    • Jerjes W, Sharwani A, Swinson BD, Salih V, El-Maaytah M, Hopper C (2006). Elastic scattering spectroscopy in the head and neck: detection of premalignant and malignant lesions.
    • Sharwani A, Jerjes W, Hopper C, Lewis MP, El-Maaytah M, Khalil HSM, MacRobert AJ, Upile T, Salih V (2006). Photodynamic therapy down-regulates the invasion promoting factors in human oral cancer. Archives of Oral Biology, 51(12), 1104 - 1111. doi:10.1016/j.archoralbio.2006.05.012
    • Jerjes W, Sharwani A, Salih V, Hopper C (2006). Monitoring of photobleaching in photodynamic therapy using fluorescence spectroscopy: assessment of clinical outcome.
    • Sharwani A, Jerjes W, Salih V, MacRobert AJ, El-Maaytah A, Khalil HSM, Hopper C (2006). Fluorescence spectroscopy combined with 5-aminolevulinic acid-induced protoporphyrin IX fluorescence in detecting oral premalignancy. Journal of Photochemistry and Photobiology B: Biology, 83(1), 27 - 33. doi:10.1016/j.jphotobiol.2005.11.007
    • Sharwani A, Jerjes W, Salih V, Swinson B, Bigio IJ, El-Maaytah M, Hopper C (2006). Assessment of oral premalignancy using elastic scattering spectroscopy. Oral Oncology, 42(4), 343 - 349. doi:10.1016/j.oraloncology.2005.08.008
    • Harle J, Kim H-W, Mordan NJ, Knowles JC, Salih V (2006). Initial responses of human osteoblasts to sol-gel modified titanium with hydroxyapatite and titania composition. Acta Biomaterialia, 2(5), 547 - 556. doi:10.1016/j.actbio.2006.05.005
    • Singhatanadgit W, Salih V, Olsen I (2006). Shedding of a soluble form of BMP receptor-IB controls bone cell responses to BMP. Bone, 39(5), 1008 - 1017.
    • Jerjes W, Sharwani A, Hopper C, Salih V (2006). Cisplatin augments photodynamic therapy-anti-tumour activity and down regulate invasion.
    • Jerjes W, Sharwani A, Hopper C, Salih V (2006). Cellular uptake and photodynamic efficacy of Foscan on head and neck carcinoma cells.
    • Singhatanadgit W, Salih V, Olsen I (2006). Bone morphogenetic protein receptors and bone morphogenetic protein signaling are controlled by tumor necrosis factor-à in human bone cells. The International Journal of Biochemistry and Cell Biology, 38(10), 1794 - 1807. doi:10.1016/j.biocel.2006.05.005
    • Singhatanadgit W, Salih V, Olsen I (2006). Up-regulation of bone morphogenetic protein receptor IB by growth factors enhances BMP-2-induced human bone cell functions. Journal of Cellular Physiology, 209(3), 912 - 922. doi:10.1002/jcp.20799

    2005

    • Singhatanadgit W, Salih V, Olsen I (2005). Regulation of BMP receptors by cytokines in human periodontal cells.
    • Sharwani A, Jerjes W, Salih V, Hopper C (2005). Assessment of oral premalignancy using elastic scattering spectroscopy.
    • Lewis MP, Salih V, Knowles JC, Bitar M (2005). Biocompatible phosphate glass fibre scaffolds.
    • Sharwani A, Jerjes W, Salih V, Hopper C (2005). Fluorescence spectroscopy combined with 5-aminolevulinic acid induced protoporphyrin IX fluorescence in detecting oral premalignancy.
    • Sharwani A, Jerjes W, Salih V, Hopper C (2005). Monitoring of photobleaching in photodynamic therapy using fluorescence spectroscopy: assessment of the clinical outcome.
    • Kim H-W, Kim H-E, Salih V, Knowles JC (2005). Hydroxyapatite and titania sol-gel composite coatings on titanium for hard tissue implants; mechanical and in vitro biological performance. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 72B(1), 1 - 8.
    • Kim H-W, Lee E-J, Kim H-E, Salih V, Knowles JC (2005). Effect of fluoridation of hydroxyapatite in hydroxyapatite-polycaprolactone composites on osteoblast activity. Biomaterials, 26(21), 4395 - 4404. doi:10.1016/j.biomaterials.2004.11.008
    • Kim H-W, Kim H-E, Salih V (2005). Stimulation of osteoblast responses to biomimetic nanocomposites of gelatin-hydroxyapatite for tissue engineering scaffolds. Biomaterials, 26(25), 5221 - 5230. doi:10.1016/j.biomaterials.2005.01.047
    • Bitar M, Knowles JC, Lewis MP, Salih V (2005). Soluble phosphate glass fibres for repair of bone-ligament interface. Journal of Materials Science: Materials in Medicine, 16(12), 1131 - 1136.
    • Kim H-W, Kim H-E, Salih V, Knowles JC (2005). Sol-gel-modified titanium with hydroxyapatite thin films and effect on osteoblast-like cell responses. Journal of Biomedical Materials Research Part A, 74(3), 294 - 305.
    • Bitar M, Salih V, Knowles JC, Lewis MP (2005). Phosphate-based glass fibre system: an inductive approach to bone-ligament interface repair.
    • Harle J, Mayia F, Olsen I, Salih V (2005). Effects of ultrasound on transforming growth factor-B genes in bone cells. European Cells and Materials, 10(1), 70 - 77.

    2004

    • Harle J, Salih V, Olsen I, Jones FH, Tonetti MS, Brett PM (2004). Analysis of bone cell responses to titanium surface roughness.
    • Kim H-W, Kim H-E, Salih V, Knowles JC (2004). Dissolution control and cellular responses of calcium phosphate coatings on zirconia porous scaffold. Journal of Biomedical Materials Research Part A, 68(3), 522 - 530.
    • Notingher I, Jell G, Lohbauer U, Salih V, Hench LL (2004). In situ non-invasive spectral discrimination between bone cell phenotypes used in tissue engineering. Journal of Cellular Biochemistry, 92(6), 1180 - 1192. doi:10.1002/jcb.20136
    • Brett PM, Harle J, Salih V, Mihoc R, Olsen I, Jones FH, Tonetti MS (2004). Roughness response genes in osteoblasts. Bone, 35(1), 124 - 133. doi:10.1016/j.bone.2004.03.009
    • Bitar M, Salih V, Mudera V, Knowles JC, Lewis MP (2004). Soluble phosphate glasses: in vitro studies using human cells of hard and soft tissue origin. Biomaterials, 25(12), 2283 - 2292. doi:10.1016/j.biomaterials.2003.08.054
    • Harle J, Salih V, Olsen I, Brett PM, Jones FH, Tonetti MS (2004). Gene expression profiling of bone cells on smooth and rough titanium surfaces. Journal of Materials Science: Materials in Medicine, 15(11), 1255 - 1258.
    • Kim H-W, Knowles JC, Salih V, Kim H-E (2004). Hydroxyapatite and fluor-hydroxyapatite layered film on titanium processed by a sol-gel route for hard-tissue implants. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 71B(1), 66 - 76.
    • Sabino MA, Ajami D, Salih V, Nazhat SN, Vargas-Coronado R, Cauich-Rodriguez JV, Ginebra MP (2004). Physicochemical, mechanical, and biological properties of bone cements prepared with functionalized methacrylates. Journal of Biomaterials Applications, 19(2), 147 - 161.
    • Brett PM, Harle J, Salih V, Olsen I, Jones FH, Tonetti MS (2004). The axl genes in osteoblast response to titanium in vitro.
    • Bitar M, Knowles JC, Salih V, Lewis MP (2004). Biocompatible phosphate glass fibre scaffolds engineering of the hard/ soft tissue interface.
    • Kim HW, Kim HE, Salih V, Knowles JC (2004). Dissolution control and cellular responses of calcium phosphate coatings on zirconia porous scaffold. J BIOMED MATER RES A, 68A(3), 522 - 530. doi:10.1002/jbm.a..20094

    2002

    • Brett PM, Salih V, Olsen I, Tonetti M (2002). Effects of titanium surfaces on osteoblast gene expression profiles.. J DENT RES, 81, A233 - A233.
    • Franks K, Salih V, Knowles JC, Olsen I (2002). The effect of MgO on the solubility behavior and cell proliferation in a quaternary soluble phosphate based glass system. Journal of Materials Science: Materials in Medicine, 13(6), 549 - 556.
    • Bitar M, Ahmed I, Knowles JC, Salih V, Lewis MP (2002). Development of novel soluble glasses for tissue engineering of hard tissue.
    • Brett PM, Salih V, Olsen I, Tonetti MS (2002). Effects of titanium surfaces on osteoblast gene expression profiles.

    2001

    • Salih V, Georgiou G, Knowles JC, Olsen I (2001). Glass reinforced hydroxyapatite for hard tissue surgery - Part II: in vitro evaluation of bone cell growth and function. Biomaterials, 22(20), 2817 - 2824. doi:10.1016/S0142-9612(01)00026-6
    • Harle J, Salih V, Mayia F, Knowles JC, Olsen I (2001). Effects of ultrasound on the growth and function of bone and periodontal ligament cells in vitro. Ultrasound in Medicine and Biology, 27(4), 579 - 586.
    • Harle J, Salih V, Knowles JC, Mayia F, Olsen I (2001). Effects of therapeutic ultrasound on osteoblast gene expression. Journal of Materials Science: Materials in Medicine, 12(10-12), 1001 - 1004.
    • Salih V, Knowles JC, O'Hare MJ, Olsen I (2001). Retroviral transduction of alveolar bone cells with a temperature-sensitive SV40 large T antigen. Cell and Tissue Research, 304(3), 371 - 376. doi:10.1007/s004410100391

    2000

    • Salih V, Franks K, James M, Hastings GW, Knowles JC (2000). Development of soluble glasses for biomedical use. Part II: the biological response of human osteoblast cell lines to phosphate-based soluble glasses. Journal of Materials Science: Materials in Medicine, 11(10), 615 - 620.
    • Salih V, Knowles JC, O'Hare MJ, Olsen I (2000). Establishment of long-term cultures of alveolar bone cells.
    • Harle J, Salih V, Knowles JC, Mayia F, Olsen I (2000). Flow cytometry analysis of bone and periodontal cell response to ultrasound.

    1999

    • Salih V, Franks K, James M, Hastings GW, Knowles JC, Olsen I (1999). Biological response of human osteoblasts to soluble glasses.

    1998

    • Salih V, Jalisi IM, Lee DA, Franks K, Hastings GW, Knowles JC, Olsen I (1998). The response of human osteoblast cell lines to phosphate based soluble glasses.

    1997

    • Lee DA, Salih V, Stockton EF, Stanton JS, Bentley G (1997). Effect of normal synovial fluid on the metabolism of articular chondrocytes in vitro.. Clin Orthop Relat Res, (342), 228 - 238.
    • Lee DA, Salih V, Stockton EF, Stanton JS, Bentley G (1997). The effect of normal synovial fluid on the metabolism of the bovine articular chondrocytes in vitro. Clinical Orthopaedics and Related Research, 342, 228 - 238.

    1996

    • Bittinger F, Muhlbayer S, Salih V, Grau M, Richter HA, Klein CL, Kirkpatrick CJ (1996). Experimental studies on the suitability of human mesothelial cells for seeding vascular prostheses - shear-stress resistance in vitro.. Journal of Materials Science: Materials in Medicine, 7(9), 543 - 550.

    1995

    • Stanton JS, Salih V, Bentley G, Downes S (1995). The growth of chondrocytes using Gelfoam(R) as a biodegradable scaffold. Journal of Materials Science: Materials in Medicine, 6(12), 739 - 744.

    1993

    • Coumbe A, Keefe MB, Salih V, Reynolds PS, Graham TR, Berry CL (1993). Pathological sequelae of implantation of intracorporeal left ventricular assist devices in the calf. American Journal of Cardiovascular Pathology, 4(4), 302 - 316.
    • Kuo J, Ramstead K, Salih V, Coumbe A, Graham TR, Lewis CT (1993). Effect of vascular clamp on endothelial integrity of the internal mammary artery. The Annals of Thoracic Surgery, 55(4), 923 - 926.
    • Martin JE, Benson M, Swash M, Salih V, Gray A (1993). Myofibroblasts in hollow visceral myopathy: the origin of gastrointestinal fibrosis?. Gut, 34(7), 999 - 1001.
    • Salih V, Graham TR, Berry CL, Coumbe A, Smith SC, Dasse K, Frazier OH (1993). The lining of textured surfaces in implantable left ventricular assist devices: an immunocytochemical and electronmicroscopic study. American Journal of Cardiovascular Pathology, 4(4), 317 - 325.

    1992

    • Salih V, Greenwald SE, Chong CF, Coumbe A, Berry CL (1992). The development of an in-vitro perfusion system for studies on cultured cells. International Journal of Experimental Pathology, 73(5), 625 - 632.
    • SALIH V, KUO J, COUMBE A, RAMSTEAD K, GRAHAM TR, LEWIS CT (1992). CLAMPING OF INTERNAL MAMMARY ARTERY GRAFTS DURING BYPASS-SURGERY - EFFECTS ON VESSEL WALL. J PATHOL, 168, A153 - A153.

    1991

    • SALIH V, BITTINGER F, YONEMITSU N, MITTERMAYER C, KIRKPATRICK CJ (1991). ANGIOGENESIS INVITRO - COMPARISON OF 2 TECHNIQUES TO ISOLATE MICROVASCULAR ENDOTHELIAL-CELLS FROM HUMAN OMENTUM. J PATHOL, 163(2), A160 - A160.

    1990

    • GRAHAM TR, DASSE K, COUMBE A, SALIH V, FRAZIER OH, LEWIS CT (1990). HOST GENERATED NEOINTIMAL LININGS WITHIN AN IMPLANTABLE TEXTURED SURFACE LEFT-VENTRICULAR ASSIST DEVICE (433 TOTAL PATIENT DAYS). BRIT HEART J, 64(1), 73 - 73.
    • RADIA DH, REYNOLDS PS, SYNDERCOMBECOURT YD, COUMBE A, GRAHAM TR, SALIH V, LEWIS CT, BERRY CL (1990). EVALUATION OF PHYSIOLOGICAL AND HEMATOLOGICAL PARAMETERS IN AN INVITRO CIRCULATORY LOOP. J PATHOL, 161(4), A346 - A346.
    • SALIH V, GRAHAM TR, ALLAN A, REYNOLDS PS, DASSE K, LEWIS CT (1990). A NOVEL PERCUTANEOUS ACCESS DEVICE SUITABLE FOR LONG-TERM USE. J PATHOL, 161(4), A350 - A350.
    • Allan A, Graham TR, Withington PS, Salih V, Dasse K, Lewis CT (1990). A new porous polyurethane percutaneous access device. Journal of Cardiothoracic Anesthesia, 4(6 SUPPL. 3), 24 - 24.
    • COUMBE A, GRAHAM TR, SALIH V, DASSE K, FRAZIER OH, LEWIS CT (1990). EVALUATION OF NEOINTIMA DEVELOPING OVER TEXTURED SURFACES WITHIN LEFT-VENTRICULAR DEVICES DURING CLINICAL USE. J PATHOL, 160(2), A159 - A159.
    • Graham TR, Dasse K, Coumbe A, Salih V, Marrinan MT, Frazier OH, Lewis CT (1990). Neo-intimal development on textured biomaterial surfaces during clinical use of an implantable left ventricular assist device. European Journal of Cardio-Thoracic Surgery, 4(4), 182 - 190.
    • GRAHAM TR, COURT DS, SALIH V, LEWIS CT (1990). TEXTURED SURFACE LEFT-VENTRICULAR ASSIST DEVICES CONTINUE TO CONSUME PLATELETS AFTER INTERMEDIATE TERM IMPLANTATION IN THE CALF MODEL. BRIT HEART J, 64(1), 97 - 97.
    • Allan A, Graham TR, Withington PS, Salih V, Dasse KA, Poirier VL, Lewis CT (1990). Development of a polyurethane percutaneous access device for long-term vascular access.. ASAIO Trans, 36(3), M349 - M351.
    • REYNOLDS PS, GRAHAM TR, SALIH V, SYNDERCOMBECOURT YD, LEWIS CT (1990). BLOOD INTERACTION WITH GRAFT BIOMATERIALS IN AN INVITRO CIRCULATORY LOOP. J PATHOL, 161(4), A346 - A346.

    1989

    • SALIH V, GRAHAM TR, REYNOLDS PS, COUMBE A, LEWIS CT, BERRY CL (1989). IMPLANTATION OF TEXTURED SURFACE LEFT-VENTRICULAR ASSIST DEVICES (TSLVADS) IN THE CALF-EVALUATION OF NEOINTIMAL DEVELOPMENT. J PATHOL, 158(4), A353 - A353.
    • REYNOLDS PS, COUMBE A, SALIH V, GRAHAM TR, LEWIS CT, BERRY CL (1989). EVALUATION OF THE BLOOD BIOMATERIAL INTERFACE WITHIN PERFUSION CHAMBERS IN AN INVITRO CIRCULATORY LOOP. J PATHOL, 158(4), A353 - A353.
    • COUMBE A, GRAHAM TR, SALIH V, KEEFE M, LEWIS CT, BERRY CL (1989). PATHOLOGICAL-CHANGES FOLLOWING EXPERIMENTAL IMPLANTATION OF LEFT-VENTRICULAR ASSIST DEVICES IN CALVES. J PATHOL, 158(4), A346 - A346.

    • Misra SK, Philip SE, Chrzanowski W, Nazhat SN, Roy I, Knowles JC, Salih V, Boccaccini AR (). Incorporation of vitamin E in poly(3hydroxybutyrate)/Bioglass composite films: effect on surface properties and cell attachment.. Journal of the Royal Society Interface, , - .
    • Singhatanadgit W, Salih V, Olsen I (). Shedding of a soluble form of BMP receptor-IB controls bone cell responses to BMP. Bone, , - .
    • Zhao X, Olsen I, Li H, Gellynck K, Buxton PG, Knowles JC, Salih V, Young AM (). Reactive calcium phosphate - containing poly (ester-co-ether) methacrylate bone adhesives: chemical, mechanical and biological considerations. Acta Biomaterialia, , - .
    • Bitar M, Salih V, Knowles JC, Lewis MP (). Iron-phosphate glass fiber scaffolds for the hard-soft interface regeneration: The effect of fiber diameter and flow culture condition on cell survival and differentiation. Journal of Biomedical Materials Research Part A, , - .