Prof Steve Wilson

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Personal Profile

Name: Steve Wilson Email: s.wilson@ucl.ac.uk
Title: Prof Tel: 020 3549 5515
Department: Cell & Developmental Biology Fax: 020 7679 7349
Position: Professor of Developmental Biology Address: Anatomy Building, UCL, London, WC1E 6BT
Research Domain: Basic Life Sciences, Biomedical Imaging (Frontier Disciplines), Genetics (Frontier Disciplines), Neuroscience, Stem Cells & Regenerative Medicine (Frontier Disciplines) Web Page: Personal Web Page

Profile

Research Description

Brain patterning: A major focus for our research has been to elucidate the signalling pathways that establish anterior-posterior, dorsoventral and left-right pattern in the brain.  For instance, we showed that mutations and manipulations that modulate Wnt signalling within the neural plate change the allocation of regional fates in both forebrain and eyes. Furthermore, our studies of morphogenesis and cell movements led to the demonstration of critical roles for a non-canonical Wnt-PCP pathway during both mesodermal and CNS morphogenesis. 


Eye development:  One current focus for our research is to resolve the genetic bases of, and cellular mechanisms underlying, eye specification and morphogenesis with a linked goal of understanding why MAC (microphthalmia, anopthalmia and coloboma) phenotypes can arise when eye formation is disrupted. One approach is to use high-resolution time-lapse imaging to characterize the cell and tissue movements accompanying eye formation and to couple this with genetic screens to identify mutations that disrupt eye formation.


Brain asymmetry: Research from the our lab has helped to establish the zebrafish as by far the leading vertebrate model to study the development of brain asymmetry.   We have shown that breaking of symmetry and allocation of handedness to the asymmetry are separable processes and that Nodal, Wnt and Fgf pathways together break symmetry and determine its laterality.   Complementing genetic studies, his team are analyzing the developmental neuroanatomy of the brain, particularly with respect to asymmetric circuitry.   For instance, we have shown that the left and right habenular nuclei project to different regions of their target nucleus, and that for individual neurons, left-right asymmetry is manifest as differences in axon terminal morphology and targeting.  


 These neuroanatomical studies underpin research that aims to link circuitry to neuronal activity and behaviour.   One major challenge is to identify complex behaviours that are sufficiently robust to be amenable to both genetic and neuroanatomical interrogation.  To this end, we, and others, are developing assays for simple learning and fear responses and social interactions in fry.  Coupled to analysing behaviour, his lab is using genetic/optogenetic approaches to interrogate neuronal activity in lateralised brain nuclei.  We have recently found that the left and right habenulae respond to different sensory stimuli and that loss of brain asymmetry impairs the ability to respond to such stimuli.  The long-term goal of our research is to be able to move seamlessly from genes through developmental mechanisms to circuits and behaviour in the intact developing animal. 

 

 The UCL zebrafish website will give you more details of some of our lab’s research projects and publications (www.ucl.ac.uk/zebrafish-group/)


Research Activities

Blinding diseases (genetics and mechanisms)

Brain asymmetry

Mechanisms that underlie patterning and development of neurons in the vertebrate forebrain.

Mechanisms underlying morphogenetic movements

Education Description

UCL Collaborators

Prof Alison Hardcastle; Prof Mike Cheetham; Dr Masazumi Tada; Prof Philip Beales; Prof Tony Moore; Prof Andrew Webster; Dr Maryse Bailly; Prof Susan Povey

External Collaborators

Publications

    2015

    • Naville M, Louis A, Roest Crollius H, Ishibashi M, Rinkwitz S, Manning E, Becker TS, Ferg M, Rastegar S, Strähle U, Bengani H, Van Heyningen V, Fitzpatrick DR, Krecsmarik M, Bally-Cuif L, Hawkins TA, Wilson SW, Chilamakuri CSR, Wilson DI, Lucy Raymond F, Lenhard B (2015). Long-range evolutionary constraints reveal cis-regulatory interactions on the human X chromosome. Nature Communications, 6, - . doi:10.1038/ncomms7904
    • Bazin-Lopez N, Valdivia LE, Wilson SW, Gestri G (2015). Watching eyes take shape.. Current opinion in genetics & development, 32C, 73 - 79. doi:10.1016/j.gde.2015.02.004
    • Sibley CR, Emmett W, Blazquez L, Faro A, Haberman N, Briese M, Trabzuni D, Ryten M, Weale ME, Hardy J, Modic M, Curk T, Wilson SW, Plagnol V, Ule J (2015). Recursive splicing in long vertebrate genes.. Nature, , - . doi:10.1038/nature14466

    2014

    • Hüsken U, Stickney HL, Gestri G, Bianco IH, Faro A, Young RM, Roussigne M, Hawkins TA, Beretta CA, Brinkmann I, Paolini A, Jacinto R, Albadri S, Dreosti E, Tsalavouta M, Schwarz Q, Cavodeassi F, Barth AK, Wen L, Zhang B, Blader P, Yaksi E, Poggi L, Zigman M, Lin S, Wilson SW, Carl M (2014). Tcf7l2 is required for left-right asymmetric differentiation of habenular neurons.. Curr Biol, 24(19), 2217 - 2227. doi:10.1016/j.cub.2014.08.006
    • Cardozo MJ, Sánchez-Arrones L, Sandonis A, Sánchez-Camacho C, Gestri G, Wilson SW, Guerrero I, Bovolenta P (2014). Cdon acts as a Hedgehog decoy receptor during proximal-distal patterning of the optic vesicle.. Nat Commun, 5, 4272 - . doi:10.1038/ncomms5272
    • Dreosti E, Vendrell Llopis N, Carl M, Yaksi E, Wilson SW (2014). Left-right asymmetry is required for the habenulae to respond to both visual and olfactory stimuli.. Curr Biol, 24(4), 440 - 445. doi:10.1016/j.cub.2014.01.016

    2013

    • Colombo A, Palma K, Armijo L, Mione M, Signore IA, Morales C, Guerrero N, Meynard MM, Perez R, Suazo J, Marcelain K, Briones L, Haertel S, Wilson SW, Concha ML (2013). Daam1a mediates asymmetric habenular morphogenesis by regulating dendritic and axonal outgrowth. DEVELOPMENT, 140(19), 3997 - 4007. doi:10.1242/dev.091934
    • Fodor E, Zsigmond A, Horvath B, Molnar J, Nagy I, Toth G, Wilson SW, Varga M (2013). Full Transcriptome Analysis of Early Dorsoventral Patterning in Zebrafish. PLOS ONE, 8(7), - . doi:10.1371/journal.pone.0070053
    • Ivanovitch K, Cavodeassi F, Wilson SW (2013). Precocious Acquisition of Neuroepithelial Character in the Eye Field Underlies the Onset of Eye Morphogenesis. Developmental Cell, , - . doi:10.1016/j.devcel.2013.09.023
    • Cavodeassi F, Ivanovitch K, Wilson SW (2013). Eph/Ephrin signalling maintains eye field segregation from adjacent neural plate territories during forebrain morphogenesis.. Development, 140(20), 4193 - 4202. doi:10.1242/dev.097048
    • Mahmood F, Fu S, Cooke J, Wilson SW, Cooper JD, Russell C (2013). A zebrafish model of CLN2 disease is deficient in tripeptidyl peptidase 1 and displays progressive neurodegeneration accompanied by a reduction in proliferation. BRAIN, 136, 1488 - 1507. doi:10.1093/brain/awt043

    2012

    • Andreazzoli M, Gestri G, Landi E, D'Orsi B, Barilari M, Iervolino A, Vitiello M, Wilson SW, Dente L (2012). Kidins220/ARMS interacts with Pdzrn3, a protein containing multiple binding domains.. Biochimie, 94(9), 2054 - 2057. doi:10.1016/j.biochi.2012.05.002
    • Cerveny KL, Varga M, Wilson SW (2012). Continued growth and circuit building in the anamniote visual system.. Dev Neurobiol, 72(3), 328 - 345. doi:10.1002/dneu.20917
    • Roussigne M, Blader P, Wilson SW (2012). Breaking symmetry: The zebrafish as a model for understanding left-right asymmetry in the developing brain. DEVELOPMENTAL NEUROBIOLOGY, 72(3), 269 - 281. doi:10.1002/dneu.20885
    • Takesono A, Moger J, Faroq S, Cartwright E, Dawid IB, Wilson SW, Kudoh T (2012). Solute carrier family 3 member 2 (Slc3a2) controls yolk syncytial layer (YSL) formation by regulating microtubule networks in the zebrafish embryo. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109(9), 3371 - 3376. doi:10.1073/pnas.1200642109
    • Folgueira M, Bayley P, Navratilova P, Becker TS, Wilson SW, Clarke JD (2012). Morphogenesis underlying the development of the everted teleost telencephalon.. Neural Dev, 7, 32 - . doi:10.1186/1749-8104-7-32
    • Concha ML, Bianco IH, Wilson SW (2012). Encoding asymmetry within neural circuits. NATURE REVIEWS NEUROSCIENCE, 13(12), 832 - 843. doi:10.1038/nrn3371
    • Chiavacci E, Dolfi L, Verduci L, Meghini F, Gestri G, Evangelista AM, Wilson SW, Cremisi F, Pitto L (2012). MicroRNA 218 mediates the effects of Tbx5a over-expression on zebrafish heart development.. PLoS One, 7(11), e50536 - . doi:10.1371/journal.pone.0050536

    2011

    • Dente L, Gestri G, Tsang M, Kudoh T, Wilson SW, Dawid IB, Andreazzoli M (2011). Cloning and developmental expression of zebrafish pdzrn3.. Int J Dev Biol, 55(10-12), 989 - 993. doi:10.1387/ijdb.113437ld
    • Andoniadou CL, Signore M, Young RM, Gaston-Massuet C, Wilson SW, Fuchs E, Martinez-Barbera JP (2011). HESX1- and TCF3-mediated repression of Wnt/β-catenin targets is required for normal development of the anterior forebrain.. Development, 138(22), 4931 - 4942. doi:10.1242/dev.066597
    • Valdivia LE, Young RM, Hawkins TA, Stickney HL, Cavodeassi F, Schwarz Q, Pullin LM, Villegas R, Moro E, Argenton F, Allende ML, Wilson SW (2011). Lef1-dependent Wnt/β-catenin signalling drives the proliferative engine that maintains tissue homeostasis during lateral line development.. Development, 138(18), 3931 - 3941. doi:10.1242/dev.062695
    • Lupo G, Gestri G, O'Brien M, Denton RM, Chandraratna RA, Ley SV, Harris WA, Wilson SW (2011). Retinoic acid receptor signaling regulates choroid fissure closure through independent mechanisms in the ventral optic cup and periocular mesenchyme.. Proc Natl Acad Sci U S A, 108(21), 8698 - 8703. doi:10.1073/pnas.1103802108

    2010

    • Cerveny KL, Cavodeassi F, Turner KJ, de Jong-Curtain TA, Heath JK, Wilson SW (2010). The zebrafish flotte lotte mutant reveals that the local retinal environment promotes the differentiation of proliferating precursors emerging from their stem cell niche.. Development, 137(13), 2107 - 2115. doi:10.1242/dev.047753
    • Ewan K, Pajak B, Stubbs M, Todd H, Barbeau O, Quevedo C, Botfield H, Young R, Ruddle R, Samuel L, Battersby A, Raynaud F, Allen N, Wilson S, Latinkic B, Workman P, McDonald E, Blagg J, Aherne W, Dale T (2010). A useful approach to identify novel small-molecule inhibitors of Wnt-dependent transcription.. Cancer Res, 70(14), 5963 - 5973. doi:10.1158/0008-5472.CAN-10-1028
    • Cruz C, Maegawa S, Weinberg ES, Wilson SW, Dawid IB, Kudoh T (2010). Induction and patterning of trunk and tail neural ectoderm by the homeobox gene eve1 in zebrafish embryos. Proceedings of the National Academy of Sciences of the United States of America, 107(8), 3564 - 3569. doi:10.1073/pnas.1000389107
    • Fantin A, Vieira JM, Gestri G, Denti L, Schwarz Q, Prykhozhij S, Peri F, Wilson SW, Ruhrberg C (2010). Tissue macrophages act as cellular chaperones for vascular anastomosis downstream of VEGF-mediated endothelial tip cell induction.. Blood, 116(5), 829 - 840. doi:10.1182/blood-2009-12-257832
    • Tschopp M, Takamiya M, Cerveny KL, Gestri G, Biehlmaier O, Wilson SW, Strähle U, Neuhauss SC (2010). Funduscopy in adult zebrafish and its application to isolate mutant strains with ocular defects.. PLoS One, 5(11), e15427 - . doi:10.1371/journal.pone.0015427

    2009

    • Regan JC, Concha LM, Roussigne M R, C W, S W (2009). An Fgf8-Dependent Bistable Cell Migratory Event Establishes CNS Asymmetry. Neuron, 61(1), 27 - 34. doi:10.1016/j.neuron.2008.11.030
    • Roussigné M, Bianco IH, Wilson SW, Blader P (2009). Nodal signalling imposes left-right asymmetry upon neurogenesis in the habenular nuclei. Development, 136(9), 1549 - 1557. doi:10.1242/dev.034793
    • Carreira-Barbosa F, Kajita M, Morel V, Wada H, Okamoto H, Martinez Arias A, Fujita Y, Wilson SW, Tada M (2009). Flamingo regulates epiboly and convergence/extension movements through cell cohesive and signalling functions during zebrafish gastrulation. Development, 136, 383 - 392. doi:10.1242/dev.026542
    • Picker A, Cavodeassi F, Machatem A, Bernauer S, Hans S, Abe G, Kawakami K, Wilson SW, Brand M2009 (2009). Dynamic coupling of pattern formation and morphogenesis in the developing vertebrate retina. PLoS Biology, 7(10), - . doi:10.1371/journal.pbio.1000214
    • McMahon C, Gestri G, Wilson SW, Link BA (2009). Lmx1b is essential for survival of periocular mesenchymal cells and influences Fgf-mediated retinal patterning in zebrafish.. Developmental Biology, 332(2), 287 - 298. doi:10.1016/j.ydbio.2009.05.577
    • Gestri G, Osborne RJ, Wyatt AW, Gerrelli D, Gribble S, Stewart H, Fryer A, Bunyan DJ, Prescott K, Collin JRO, Fitzgerald T, Robinson D, Carter NP, Wilson SW, Ragge NK (2009). Reduced TFAP2A function causes variable optic fissure closure and retinal defects and sensitizes eye development to mutations in other morphogenetic regulators. Human Genetics, 126(6), 791 - 803.
    • Cavodeassi F, Kapsimali M, Wilson SWY, R (2009). Forebrain: early development. In Squire LR (Ed.), Encyclopedia of Neuroscience (pp. 321 - 325). : Elsevier.
    • Ferrante MI, Romio L, Castro S, Collins JE, Goulding DA, Stemple DL, Woolf AS, Wilson SW (2009). Convergent Extension Movements and Ciliary Function are Mediated by ofd1, A Zebrafish Orthologue of the Human Oral-Facial-Digital Type 1 Syndrome Gene.. Human Molecular Genetics, 18(2), 289 - 303. doi:10.1093/hmg/ddn356
    • Castleman VH, Romio L, Chodhari R, Hirst RA, de Castro SC, Parker KA, Ybot-Gonzalez P, Emes RD, Wilson SW, Wallis C, Johnson CA, Herrera RJ, Rutman A, Dixon M, Shoemark A, Bush A, Hogg C, Gardiner RM, Reish O, Greene ND, O 'Callaghan C, Purton S, Chung EM, Mitchison HM (2009). Mutations in Radial Spoke Head Protein Genes RSPH9 and RSPH4A Cause Primary Ciliary Dyskinesia with Central-Microtubular-Pair Abnormalities.. The American Journal of Human Genetics, 84(2), 197 - 209. doi:10.1016/j.ajhg.2009.01.011

    2008

    • Bianco IH, Wilson SW (2008). The habenular nuclei: a conserved asymmetric relay station in the vertebrate brain.. Philosophical Transactions of the Royal Society B: Biological Sciences, epub, - .
    • Hawkins TA, Haramis A-P, Etard C, Prodromou C, Vaughan CK, Ashworth R, Ray S, Behra M, Holder N, Talbot WS, Pearl LH, Strähle U, Wilson SW (2008). The ATPase-dependent chaperoning activity of Hsp90a regulates thick filament formation and integration during skeletal muscle myofibrillogenesis. Development, 135(6), 1147 - 1156. doi:10.1242/dev.018150
    • Bianco IH, Carl M, Russell C, Clarke JDW, Wilson SW (2008). Brain asymmetry is encoded at the level of axon terminal morphology. Neural Development, 3(1), 9 - .

    2007

    • Kapsimali M, Kloosterman WP, de Bruijn E, Rosa F, Plasterk RHA, Wilson SW (2007). MicroRNAs show a wide diversity of expression profiles in the developing and mature central nervous system. Genome Biology, 8(8), R173 - . doi:10.1186/gb-2007-8-8-r173
    • Carl M, Bianco IH, Bajoghli B, Aghaallaei N, Czerny T, Wilson SW (2007). Wnt/Axin1/ß-catenin signaling regulates asymmetric Nodal activation, elaboration, and concordance of CNS asymmetries. Neuron, 55(3), 393 - 405. doi:10.1016/j.neuron.2007.07.007
    • Hadzhiev Y, Lele Z, Schindler S, Wilson SW, Ahlberg A, Straehle U, Mueller F (2007). Hedgehog signaling patterns the outgrowth of unpaired skeletal appendages in zebrafish. BMC Developmental Biology, 7(1), 75 - . doi:10.1186/1471-213X-7-75

    2006

    • Costagli A, Felice B, Guffanti A, Wilson SW, Mione M (2006). Identification of alternatively spliced dab1 isoforms in zebrafish. Development, Genes and Evolution, 216(6), 291 - 299.
    • Aligianis IA, Morgan NV, Mione M, Johnson CA, Rosser E, Hennekam RC, Adams G, Trembath RC, Pilz DT, Stoodley N, Moore AT, Wilson S, Maher ER (2006). Mutation in Rab3 GTPase-activating protein (RAB3GAP) noncatalytic subunit in a kindred with Martsolf syndrome. The American Journal of Human Genetics, 78(4), 702 - 707.
    • Jeong JY, Einhorn Z, Mercurio S, Lee S, Lau B, Mione M, Wilson SW, Guo S (2006). Neurogenin1 is a determinant of zebrafish basal forebrain dopaminergic neurons and is regulated by the conserved zinc finger protein Tof/Fezl. Proceedings of the National Academy of Sciences of the United States of America, 103, 5143 - 5148.

    2005

    • Norton WH, Mangoli M, Lele Z, Pogoda HM, Diamond B, Mercurio S, Russell C, Teraoka H, Stickney HL, Rauch GJ, Heisenberg CP, Houart C, Schilling TF, Frohnhoefer HG, Rastegar S, Neumann CJ, Gardiner RM, Strahle U, Geisler R, Rees M, Talbot WS, Wilson SW (2005). Monorail/Foxa2 regulates floorplate differentiation and specification of oligodendrocytes, serotonergic raphe neurones and cranial motoneurones.. Development, 132(4), 645 - 658. doi:10.1242/dev.01611
    • Gestri G, Carl M, Appolloni I, Wilson SW, Barsacchi G, Andreazzoli M (2005). Six3 functions in anterior neural plate specification by promoting cell proliferation and inhibiting Bmp4 expression.. Development, 132(10), 2401 - 2413. doi:10.1242/dev.01814
    • Aizawa H, Bianco IH, Hamaoka T, Miyashita T, Uemura O, Concha ML, Russell C, Wilson SW, Okamoto H (2005). Laterotopic representation of left-right information onto the dorso-ventral axis of a zebrafish midbrain target nucleus. Current Biology, 15, 238 - 243.
    • Barth KA, Miklosi A, Watkins J, Bianco IH, Wilson SW, Andrew RJ (2005). fsi zebrafish show concordant reversal of laterality of viscera, neuroanatomy, and a subset of behavioral responses.. Current Biology, 15, 844 - 850.
    • Cavodeassi F, Carreira-Barbosa F, Young RM, Concha ML, Allende ML, Houart C, Tada M, Wilson SW (2005). Early stages of zebrafish eye formation require the coordinated activity of Wnt11, Fz5, and the Wnt/β-catenin pathway. Neuron, 47(1), 43 - 56. doi:10.1016/j.neuron.2005.05.026

    2004

    • Wilson SW, Houart C (2004). Early steps in the development of the forebrain. Developmental Cell, 6, 167 - 181.
    • Kudoh T, Concha ML, Houart C, Dawid IB, Wilson SW (2004). Combinatorial Fgf and Bmp signalling patterns the gastrula ectoderm into prospective neural and epidermal domains. Development, 131, 3581 - 3592.
    • Teraoka H, Russell C, Regan J, Chandrasekhar A, Concha ML, Yokoyama R, Higashi K, Take-uchi M, Dong W, Hiraga T, Holder N, Wilson SW (2004). Hedgehog and Fgf signaling pathways regulate the development of tphR-expressing serotonergic raphe neurons in zebrafish embryos. Journal of Neurobiology, 60(3), 275 - 288.
    • Paukert M, Sidi S, Russell C, Siba M, Wilson SW, Nicolson T, Grunder S (2004). A family of acid-sensing ion channels from the zebrafish - Widespread expression in the central nervous system suggests a conserved role in neuronal communication. J BIOL CHEM, 279(18), 18783 - 18791. doi:10.1074/jbc.M401477200
    • Kapsimali M, Caneparo L, Houart C, Wilson SW (2004). Inhibition of Wnt/Axin/beta-catenin pathway activity promotes ventral CNS midline tissue to adopt hypothalamic rather than floorplate identity.. Development, 131(23), 5923 - 5933. doi:10.1242/dev.01453

    2003

    • Ulrich F, Concha ML, Heid PJ, Voss E, Witzel S, Roehl H, Tada M, Wilson SW, Adams RJ, Soll DR, Heisenberg CP (2003). Slb/Wnt11 controls hypoblast cell migration and morphogenesis at the onset of zebrafish gastrulation. Development, 130, 5375 - 5384. doi:10.1242/dev.00758
    • Carreira-Barbosa F, Concha ML, Takeuchi M, Ueno N, Wilson SW, Tada M (2003). Prickle1 regulates cell movements during gastrulation and neuronal migration in zebrafish. Development, 130, 4037 - 4046. doi:10.1242/dev.00567
    • Cau E, Wilson SW (2003). Ash1a and Neurogenin1 function downstream of Floating head to regulate epiphysial neurogenesis. Development, 130, 2455 - 2466.
    • Masai I, Lele Z, Yamaguchi M, Komori A, Nakata A, Nishiwaki Y, Wada H, Tanaka H, Nojima Y, Hammerschmidt M, Wilson SW, Okamoto H (2003). N-cadherin mediates retinal lamination, maintenance of forebrain compartments and patterning of retinal neurites. Development, 130, 2479 - 2494.
    • Bink RJ, Habuchi H, Lele Z, Dolk E, Joore J, Rauch GJ, Geisler R, Wilson SW, Den Hertog J, Kimata K, Zivkovic D (2003). Heparan Sulfate 6-O-Sulfotransferase is essential for muscle development in zebrafish. Journal of Biological Chemistry, 278, 31118 - 31127.
    • Barrios A, Poole RJ, Durbin L, Brennan C, Holder N, Wilson SW (2003). Eph/Ephrin signaling regulates the mesenchymal-to-epithelial transition of the paraxial mesoderm during somite morphogenesis. Current Biology, 13(18), 1571 - 1582. doi:10.1016/j.cub.2003.08.030
    • Concha ML, Russell C, Regan JC, Tawk M, Sidi S, Gilmour DT, Kapsimali M, Sumoy L, Goldstone K, Amaya E, Kimelman D, Nicolson T, Gründer S, Gomperts M, Clarke JDW, Wilson SW (2003). Local tissue interactions across the dorsal midline of the forebrain establish CNS laterality. Neuron, 39, 423 - 438. doi:10.1016/S0896-6273(03)00437-9
    • Take-Uchi M, Clarke JDW, Wilson SW (2003). Hedgehog signaling maintains the optic stalk/retinal interface through the regulation of Vax gene activity. Development, 130, 955 - 968.

    2002

    • Houart C, Caneparo L, Heisenberg CP, Barth AK, Take-Uchi M, Wilson SW (2002). Establishment of the telencephalon during gastrulation by local antagonism of Wnt signaling. Neuron, 35(2), 255 - 265. doi:10.1016/S0896-6273(02)00751-1
    • Wendl T, Lun K, Mione M, Favor J, Brand M, Wilson SW, Rohr KB (2002). Pax2.1 is required for development of thyroid follicles in zebrafish. Development, 129, 3751 - 3760.
    • Costagli A, Kapsimali M, Wilson SW, Mione M (2002). Conserved and divergent patterns of reelin expression in the zebrafish central nervous system. The Journal of Comparative Neurology, 450, 73 - 93.
    • Kudoh T, Wilson SW, Dawid IB (2002). Distinct roles for Fgf, Wnt and retinoic acid in posteriorizing the neural ectoderm. Development, 129, 4335 - 4346.
    • Mathieu J, Barth A, Rosa FM, Wilson SW, Peyrieras N (2002). Distinct and cooperative roles for Nodal and Hedgehog signals during hypothalamic development. DEVELOPMENT, 129(13), 3055 - 3065.
    • Feldman B, Concha ML, Saude L, Parsons MJ, Adams RJ, Wilson SW, Stemple DS (2002). Lefty antagonism of Squint is essential for normal gastrulation. Current Biology, 12, 2129 - 2135.
    • Grandel H, Lun K, Rauch GJ, Rhinn M, Piotrowski T, Houart C, Sordino P, Kuchler AM, Schulte-Merker S, Geisler R, Holder N, Wilson SW, Brand M (2002). Retinoic acid signalling in the zebrafish embryo is necessary during pre-segmentation stages to pattern the anterior-posterior axis of the CNS and to induce a pectoral fin bud. DEVELOPMENT, 129(12), 2851 - 2865.
    • Lele Z, Folchert A, Concha M, Rauch GJ, Geisler R, Rosa F, Wilson SW, Hammerschmidt M, Bally-Cuif L (2002). parachute/n-cadherin is required for morphogenesis and maintained integrity of the zebrafish neural tube. DEVELOPMENT, 129(14), 3281 - 3294.
    • Wilson SW, Brand M, Eisen JS (2002). Patterning the zebrafish central nervous system. In Solnica-Krezel L (Ed.), Pattern Formation in Zebrafish (pp. 181 - 215). : Springer.

    2001

    • Rohr K, Barth KA, Varga ZM, Wilson SW (2001). The nodal pathway acts upstream of Hedgehog signalling to specify ventral telencephalic identity. Neuron, 29, 341 - 351. doi:10.1016/S0896-6273(01)00210-0
    • Cooke J, Moens C, Roth L, Durbin L, Shiomi K, Brennan C, Kimmel C, Wilson SW, Holder N (2001). Eph signalling functions downstream of Val to regulate cell sorting and boundary formation in the caudal hindbrain. Development, 128(4), 571 - 580.
    • Heisenberg CP, Houart C, Take-uchi M, Rauch GJ, Masai I, Caneparo L, Concha ML, Dale TC, Wilson SW, Stemple DL (2001). A mutation in the Gsk3-binding domain of zebrafish Masterblind/Axin1 leads to a fate transformation of telencephalon and eyes to diencephalon. Genes and Development, 15, 1427 - 1434.
    • Concha ML, Wilson SW (2001). Asymmetry in the epithalamus of vertebrates. Journal of Anatomy, 199(1-2), 63 - 84.

    2000

    • Durbin L, Sordino P, Barrios A, Gering M, Thisse C, Thisse B, Brennan C, Green A, Wilson SW, Holder N (2000). Anterior-posterior patterning is required within segments for somite boundary formation in developing zebrafish. Development, 127, 1703 - 1713.
    • Masai I, Stemple DL, Okamoto H, Wilson SW (2000). Midline signals regulate retinal neurogenesis in zebrafish. Neuron, 27, 251 - 263.
    • Williams JA, Barrios A, Gatchalian C, Rubin L, Wilson SW, Holder N (2000). Programmed cell death in zebrafish Rohon Beard neurons is influenced by TrkC1/NT3 signalling. Developmental Biology, 226, 220 - 230.
    • Heisenberg CP, Tada M, Rauch GJ, Saúde L, Concha ML, Geisler R, Stemple DL, Smith JC, Wilson SW (2000). Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation.. Nature, 405(6782), 76 - 81. doi:10.1038/35011068
    • Wilson SW, Rubenstein JL (2000). Induction and dorsoventral patterning of the telencephalon. Neuron, 28, 641 - 651.
    • Shanmugalingam S, Houart C, Picker A, Reifers F, Macdonald R, Barth KA, Griffin K, Brand M, Wilson SW (2000). Ace/Fgf8.1 is required for forebrain commissure formation and patterning of the telencephalon. Development, 127, 2549 - 2561.
    • Concha M, Burdine R, Russell C, Schier AS, Wilson SW (2000). A Nodal signalling pathway regulates the laterality of CNS asymmetries in the zebrafish forebrain. Neuron, 28, 399 - 409.

    1999

    • Heisenberg C-PH, Brennan C, Wilson SW (1999). Zebrafish aussicht embryos exhibit widespread overexpression of ace (fgf8) and coincident defects in CNS development. Development, 126, 2129 - 2140.
    • Ho C-Y, Houart C, Wilson SW, Stainier DYR (1999). A role for the extraembryonic yolk syncitial layer in patterning the zebrafish embryo suggested by properties of the hex gene. Current Biology, 9, 1131 - 1135.
    • Wilson S (1999). Nigel Holder (July 2, 1953-December 11, 1998).. Developmental Biology, 208, 253 - 254.
    • Guo S, Wilson SW, Cooke S, Chitnis A, Driever W, Rosenthal A (1999). Mutations in the zebrafish unmask shared regulatory pathways controlling the development of catecholaminergic neurons. Developmental Biology, 208, 473 - 487.
    • Barth KA, Kishimoto Y, Rohr KB, Seydler C, Schulte-Merker S, Wilson SW (1999). Bmp activity establishes a gradient of positional information throughout the entire neural plate.. Development, 126(22), 4977 - 4987.
    • Guo S, Brush J, Teraoka H, Goddard A, Wilson SW, Mullins MC, Rosenthal A (1999). Development of noradrenergic neurons in the zebrafish hindbrain requires BMP, FGF8, and the homeodomain protein Soulless/Phox2a. Neuron, 24, 555 - 566.

    1998

    • Shanmugalingam S, Wilson SW (1998). Isolation, expression and regulation of a zebrafish paraxis homologue.. Mechanisms of Development, 78, 85 - 89.
    • Houart C, Westerfield M, Wilson SW (1998). A small population of anterior cells patterns the forebrain during zebrafish gastrulation.. Nature, 391(6669), 788 - 792. doi:10.1038/35853

    1997

    • Masai I, Heisenberg CP, Barth KA, Adamek S, Macdonald R, Wilson SW (1997). Floating head and masterblind regulate neuronal patterning in the roof of the forebrain. Neuron, 18, 43 - 57.
    • Cooke JE, Xu Q, Wilson SW, Holder N (1997). Characterisation of five novel Eph-related receptor tyrosine kinases suggests roles in patterning the neural plate. Development, Genes and Evolution, 206, 515 - 531.
    • Marcos-Gutierrez C, Wilson SW, Holder N, Pachnis V (1997). The zebrafish homologue of the ret receptor and its pattern of expression during embryogenesis. Oncogene, 14, 879 - 889.
    • Kazanskaya OV, Severtzova EA, Barth KA, Ermakova GV, Lukyanov SA, Benjumov AO, Pannese M, Boncinelli E, Wilson SW, Zaraisky AG (1997). Anf: a novel class of vertebrate homeobox genes expressed at the anterior end of the main embryonic axis. Gene, 200, 25 - 34.
    • Wilson SW, Brennan C, Macdonald R, Brand M, Holder N (1997). Analysis of axon tract formation in the zebrafish brain: the role of territories of gene expression and their boundaries. Cell and Tissue Research, 290, 189 - 196.
    • Macdonald R, Scholes J, Strähle U, Brennan C, Holder N, Brand M, Wilson SW (1997). The Pax protein Noi is required for commissural axon pathway formation in the rostral forebrain. Development, 124, 2397 - 2408.
    • Macdonald R, Wilson SW (1997). Distribution of Pax6 protein during eye development suggests discrete roles in proliferative and differentiated visual cells. Development, Genes and Evolution, 206, 363 - 369.

    1995

    • Macdonald R, Barth KA, Xu Q, Holder N, Mikkola I, Wilson SW (1995). Midline signalling is required for Pax gene regulation and patterning of the eyes. Development, 121(10), 3267 - 3278.
    • Barth KA, Wilson SW (1995). Expression of zebrafish nk2.2 is influenced by sonic hedgehog/vertebrate hedgehog-1 and demarcates a zone of neuronal differentiation in the embryonic forebrain. Development, 121(6), 1755 - 1768.
    • Neave B, Rodaway A, Wilson SW, Patient R, Holder N (1995). Expression of zebrafish GATA 3 (gta3) during gastrulation and neurulation suggests a role in the specification of cell fate. Mechanisms of Development, 51, 169 - 182.

    1994

    • Macdonald R, Xu Q, Barth KA, Mikkola I, Holder N, Fjose A, Krauss S, Wilson SW (1994). Regulatory gene expression boundaries demarcate sites of neuronal differentiation in the embryonic zebrafish forebrain. Neuron, 13, 1039 - 1053.

    1993

    1992

    • Bernhardt RR, Patel CK, Wilson SW, Kuwada JY (1992). Axonal trajectories and distribution of GABAergic spinal neurons in wildtype and mutant zebrafish lacking floor plate cells. The Journal of Comparative Neurology, 326, 263 - 272.
    • Mikkola I, Fjose A, Kuwada JY, Wilson S, Guddal PH, Krauss S (1992). The paired domain-containing nuclear factor pax[b] is expressed in specific commissural interneurons in zebrafish embryos. Journal of Neurobiology, 23, 933 - 946.
    • Krauss S, Maden M, Holder N, Wilson SW (1992). ebrafish pax[b] is involved in the formation of the midbrain-hindbrain boundary. Nature, 360, 87 - 89.

    1991

    • Wilson SW, Easter SSJ (1991). A pioneering growth cone in the embryonic zebrafish brain. Proceedings of the National Academy of Sciences of the United States of America, 88, 2293 - 2296.
    • Wilson SW, Easter SSJ (1991). Stereotyped pathway selection by growth cones of early epiphysial neurons in the embryonic zebrafish. Development, 112, 723 - 746.

    1990

    • Wilson SW, Ross LS, Parrett T, Easter SSJ (1990). The development of a simple scaffold of axon tracts in the brain of the embryonic zebrafish, Brachydanio rerio. Development, 108, 121 - 145.

    • Schilling T, Wilson SW (). Evolution, development and genome analysis.. Phil. Trans. R. Soc. Lond., 336(Special issue), 1517 - 1679.
    • Hitchcock PF, Macdonald RE, VanDeRyt JT, Wilson SW (). Antibodies against Pax6 immunostain amacrine and ganglion cells and neuronal progenitors, but not rod precursors, in the normal and regenerating retina of the goldfish.. J. Neurobiol., 29, 399 - 413.
    • Macdonald RE, Wilson SW (). Pax genes and eye development. Curr. Op. Neurobiol., 6, 49 - 66.