Prof Raymond Macallister

Photo

Personal Profile

Name: Raymond Macallister Email: r.macallister@ucl.ac.uk
Title: Prof Tel: 020 7679 6174
Department: Metabolism & Experi Therapeutics Fax: 020 7691 2838
Position: Professor of Clinical Pharmacology Address: Centre for Clinical Pharmacology, Ground Floor, Rayne Institute, 5 University Street, London, WC1E 6JJ
Research Domain: Cardiometabolic Science, Experimental Medicine, Neuroscience, Personalised Medicine, Populations & Lifelong Health Web Page: Personal Web Page

Profile

Research Description

Mostly translational research in healthy volunteers and patient groups, but also run basic in vitro and in vivo programmes. Main theme is remote ischaemic preconditioning, including peripheral and central neuronal mechanisms in animals and humans.

Research Activities

Education Description

UCL Collaborators

External Collaborators

Publications

    2014

    • Moyes A, Khambata R, Villar I, Bubb K, Baliga R, Lumsden N, Xiao F, Gane P, Rebstock A-S, Worthington R, Simone M, Quinteiro F, Rivilla F, Vallejo S, Peiro C, Sanchez-Ferrer CF, Djordjevic S, Caulfield M, MacAllister R, Ahluwalia A, Selwood D, Hobbs A (2014). Endothelial C-type natriuretic peptide maintains vascular homeostasis. The Journal of Clinical Investigation, , - .
    • MacAllister R, Clayton T, Knight R, Robertson S, Veighey K, Nicholas J, Loukogeorgakis S (2014). Results of the REPAIR Randomised Controlled Trial - Renal Protection Against Ischaemia Reperfusion in Transplantation..
    • Bubb KJ, Trinder SL, Baliga RS, Patel J, Clapp LH, MacAllister RJ, Hobbs AJ (2014). Inhibition of Phosphodiesterase 2 Augments cGMP and cAMP Signaling to Ameliorate Pulmonary Hypertension.. Circulation, , - . doi:10.1161/CIRCULATIONAHA.114.009751
    • Baliga RS, Scotton CJ, Trinder SL, Chambers RC, Macallister RJ, Hobbs AJ (2014). Intrinsic defence capacity and therapeutic potential of natriuretic peptides in pulmonary hypertension associated with lung fibrosis.. Br J Pharmacol, , - . doi:10.1111/bph.12694
    • Jenner W, Motwani M, Veighey K, Newson J, Audzevich T, Nicolaou A, Murphy S, MacAllister R, Gilroy DW (2014). Characterisation of Leukocytes in a Human Skin Blister Model of Acute Inflammation and Resolution. PLoS ONE, 9(3), e89375 - . doi:10.1371/journal.pone.0089375

    2013

    • Jenner W, Motwani M, Veighey K, Nicolaou A, Murphy S, MacAllister R, Gilroy D (2013). Cantharidin skin blister: a novel model for the investigation of inflammatory resolution in skin.
    • Bodalia PN, Grosso AM, Sofat R, Macallister RJ, Smeeth L, Dhillon S, Casas JP, Wonderling D, Hingorani AD (2013). Comparative efficacy and tolerability of anti-epileptic drugs for refractory focal epilepsy: systematic review and network meta-analysis reveals the need for long term comparator trials.. Br J Clin Pharmacol, 76(5), 649 - 667. doi:10.1111/bcp.12083
    • Baliga RS, Macallister RJ, Hobbs AJ (2013). Vasoactive Peptides and the Pathogenesis of Pulmonary Hypertension: Role and Potential Therapeutic Application.. Handb Exp Pharmacol, 218, 477 - 511. doi:10.1007/978-3-642-38664-0_19

    2012

    • Veighey K, Macallister RJ (2012). Clinical applications of remote ischemic preconditioning.. Cardiol Res Pract, 2012, 620681 - . doi:10.1155/2012/620681
    • Sofat R, Casas JP, Grosso AM, Prichard BNC, Smeeth L, MacAllister R, Hingorani AD (2012). Could NICE guidance on the choice of blood pressure lowering drugs be simplified?. BRITISH MEDICAL JOURNAL, 344, - . doi:10.1136/bmj.d8078
    • Baliga RS, Milsom AB, Ghosh SM, Trinder SL, Macallister RJ, Ahluwalia A, Hobbs AJ (2012). Dietary nitrate ameliorates pulmonary hypertension: cytoprotective role for endothelial nitric oxide synthase and xanthine oxidoreductase.. Circulation, 125(23), 2922 - 2932. doi:10.1161/CIRCULATIONAHA.112.100586

    2011

    • Baliga RS, MacAllister RJ, Hobbs AJ (2011). New perspectives for the treatment of pulmonary hypertension.. Br J Pharmacol, 163(1), 125 - 140. doi:10.1111/j.1476-5381.2010.01164.x
    • Okorie MI, Bhavsar DD, Ridout D, Charakida M, Deanfield JE, Loukogeorgakis SP, MacAllister RJ (2011). Postconditioning protects against human endothelial ischaemia-reperfusion injury via subtype-specific KATP channel activation and is mimicked by inhibition of the mitochondrial permeability transition pore.. Eur Heart J, 32(10), 1266 - 1274. doi:10.1093/eurheartj/ehr041
    • Grosso AM, Bodalia PN, Macallister RJ, Hingorani AD, Moon JC, Scott MA (2011). Comparative clinical- and cost-effectiveness of candesartan and losartan in the management of hypertension and heart failure: a systematic review, meta- and cost-utility analysis.. Int J Clin Pract, 65(3), 253 - 263. doi:10.1111/j.1742-1241.2011.02633.x
    • Jensen HA, Loukogeorgakis S, Yannopoulos F, Rimpilainen E, Petzold A, Tuominen H, Lepola P, MacAllister RJ, Deanfield JE, Makela T, Alestalo K, Kiviluoma K, Anttila V, Tsang V, Juvonen T (2011). Remote Ischemic Preconditioning Protects the Brain Against Injury After Hypothermic Circulatory Arrest. CIRCULATION, 123(7), 714 - 721. doi:10.1161/CIRCULATIONAHA.110.986497
    • Grosso A, Douglas I, MacAllister R, Petersen I, Smeeth L, Hingorani AD (2011). Use of the self-controlled case series method in drug safety assessment.. Expert Opin Drug Saf, 10(3), 337 - 340. doi:10.1517/14740338.2011.562187
    • Grosso AM, Bodalia PN, Macallister RJ, Hingorani AD, Moon JC, Scott MA (2011). Cost-saving opportunities and angiotensin-II receptor blocker prescribing.. Int J Clin Pract, 65(8), 912 - . doi:10.1111/j.1742-1241.2011.02730.x

    2010

    • Kapil V, Milsom AB, Okorie M, Maleki-Toyserkani S, Akram F, Rehman F, Arghandawi S, Pearl V, Benjamin N, Loukogeorgakis S, Macallister R, Hobbs AJ, Webb AJ, Ahluwalia A (2010). Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO.. Hypertension, 56(2), 274 - 281. doi:10.1161/HYPERTENSIONAHA.110.153536
    • Loukogeorgakis SP, van den Berg MJ, Sofat R, Nitsch D, Charakida M, Haiyee B, de Groot E, MacAllister RJ, Kuijpers TW, Deanfield JE (2010). Role of NADPH oxidase in endothelial ischemia/reperfusion injury in humans.. Circulation, 121(21), 2310 - 2316. doi:10.1161/CIRCULATIONAHA.108.814731
    • Derrett-Smith EC, Dooley A, Baliga R, Hobbs A, MacAllister R, Abraham D, Denton CP (2010). Perturbed VEGF signalling within the pulmonary vasculature of a TGF beta dependent mouse model of systemic sclerosis. CLIN EXP RHEUMATOL, 28(5), S63 - S63.

    2009

    • Grosso A, Douglas I, Hingorani AD, MacAllister R, Hubbard R, Smeeth L (2009). Inhaled tiotropium bromide and risk of stroke.. Br J Clin Pharmacol, 68(5), 731 - 736. doi:10.1111/j.1365-2125.2009.03517.x
    • Grosso A, Douglas I, Hingorani A, MacAllister R, Smeeth L (2009). Oral bisphosphonates and risk of atrial fibrillation and flutter in women: a self-controlled case-series safety analysis.. PLoS One, 4(3), e4720 - . doi:10.1371/journal.pone.0004720
    • Pavlidis P, Okorie MI, Jenner WJ, Deanfield JE, Loukogeorgakis SP, Macallister RJ (2009). A brief period of lower limb exercise provides remote protection against endothelial ischaemia-reperfusion injury in humans. EUROPEAN HEART JOURNAL, 30, 734 - 735.

    2008

    • Okorie MI, Williams RP, Bhavsar DD, Deanfield JE, Loukogeorgakis SP, Macallister RJ (2008). Inhibition of the mitochondrial permeability transition pore (mPTP) mimics postconditioning and protects against endothelial ischaemia reperfusion injury in humans. EUROPEAN HEART JOURNAL, 29, 9 - 9.
    • Pleiner J, Schaller G, Mittermayer F, Marsik C, MacAllister RJ, Kapiotis S, Ziegler S, Ferlitsch A, Wolzt M (2008). Intra-arterial vitamin C prevents endothelial dysfunction caused by ischemia-reperfusion. ATHEROSCLEROSIS, 197(1), 383 - 391. doi:10.1016/j.atherosclerosis.2007.06.01
    • Baliga RS, Zhao L, Madhani M, Lopez-Torondel B, Visintin C, Selwood D, Wilkins MR, MacAllister RJ, Hobbs AJ (2008). Synergy between natriuretic peptides and phosphodiesterase 5 inhibitors ameliorates pulmonary arterial hypertension.. American Journal of Respiratory and Critical Care Medicine, 178(8), 861 - 869. doi:10.1164/rccm.200801-121OC
    • Grosso A, Douglas I, Hingorani A, Macallister R, Smeeth L (2008). Post-marketing assessment of the safety of strontium ranelate; a novel case-only approach to the early detection of adverse drug reactions.. British Journal of Clinical Pharmacology, , - . doi:10.1111/j.1365-2125.2008.03273.x
    • Webb AJ, Patel N, Loukogeorgakis S, Okorie M, Aboud Z, Misra S, Rashid R, Miall P, Deanfield J, Benjamin N, MacAllister R, Hobbs AJ, Ahluwalia A (2008). Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite. HYPERTENSION, 51(3), 784 - 790. doi:10.1161/HYPERTENSIONAHA.107.103523
    • Webb A, Patel N, Loukogeorgakis S, Okorie M, Aboud Z, Misra S, Rashid R, Miall P, Deanfield J, Benjamin B, Macallister R, Hobbs A, Abluwalia A (2008). Acute blood pressure lowering and vasoprotective effects of dietary nitrate. FASEB JOURNAL, 22, - .

    2007

    • Hausenloy DJ, Mwamure PK, Venugopal V, Harris J, Barnard M, Grundy E, Ashley E, Vichare S, Di Salvo C, Kolvekar S, Hayward M, Keogh B, MacAllister RJ, Yellon DM (2007). Effect of remote ischaemic preconditioning on myocardial injury in patients undergoing CABG surgery: a randomised controlled trial.. The Lancet, 370(9587), 575 - 579. doi:10.1016/S0140-6736(07)61296-3
    • Webb AJ, Patel N, Loukogeorgakis S, Okorie M, Rashid R, Deanfield J, Benjamin N, Macallister R, Hobbs A, Ahluwalia A (2007). Acute blood pressure lowering and vasoprotective effects of beetroot juice: relationship to nitrite derived from dietary nitrate. EUROPEAN HEART JOURNAL, 28, 865 - 866.
    • Mayahi L, Heales S, Owen D, Casas JP, Harris J, MacAllister RJ, Hingorani AD (2007). (6R)-5,6,7,8-tetrahydro-L-biopterin and its stereoisomer prevent ischemia reperfusion injury in human forearm.. Arterioscler Thromb Vasc Biol, 27(6), 1334 - 1339. doi:10.1161/ATVBAHA.107.142257
    • Loukogeorgakis S, Williams R, Panagiotidou A, Kolvekar S, Donald A, Cole TJ, Yellon DM, Deanfield JE, MacAllister RJ (2007). Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism. Circulation, 116(12), 1386 - 1395. doi:10.1161/CIRCULATIONAHA.106.653782

    2006

    • Kharbanda RK, Li J, Konstantinov IE, Cheung MM, White PA, Frndova H, Stokoe J, Cox P, Vogel M, Van AG, Macallister R, Redington AN (2006). Remote ischaemic preconditioning protects against cardiopulmonary bypass-induced tissue injury: a preclinical study.. Heart, 92, 1506 - 1511.
    • Casas JP, Hingorani AD, MacAllister RJ, Smeeth L (2006). Progression of renal disease - can we forget about inhibition of the renin-angiotensin system? Authors' reply. NEPHROL DIAL TRANSPL, 21(9), 2352 - 2353. doi:10.1093/ndt/gfl316
    • Madhani M, Okorie M, Hobbs AJ, MacAllister RJ (2006). Reciprocal regulation of human soluble and particulate guanylate cyclases in vivo. British Journal of Pharmacology, 149(6), 797 - 801.
    • Marks DJ, Harbord MW, MacAllister R, Rahman FZ, Young J, Al-Lazikani B, Lees W, Novelli MR, Bllom S, Segal AW (2006). Defective acute inflammation in Crohn's disease: a clinical investigation.. The Lancet, 367(9511), 668 - 678. doi:10.1016/S0140-6736(06)68265-2
    • Loukogeorgakis SP, Panagiotidou AT, Yellon DM, Deanfield JE, MacAllister RJ (2006). Postconditioning protects against endothelial ischemia-reperfusion injury in the human forearm. Circulation, 113(7), 1015 - 1019. doi:10.1161/CIRCULATIONAHA.105.590398
    • Casas JP, Vallance P, Smeeth L, Hingorani AD, MacAllister RJ (2006). Renoprotective effects of renin-angiotensin-system inhibitors - Reply. LANCET, 367(9514), 900 - 902.

    2005

    • Loukogeorgakis SP, Panagiotidou AT, Broadhead MW, Donald A, Deanfield JE, MacAllister RJ (2005). Remote ischemic preconditioning provides early and late protection against endothelial ischemia-reperfusion injury in humans: role of the autonomic nervous system. Journal of the American College of Cardiology, 46(3), 450 - 456.
    • Casas JP, Chua W, Loukogeorgakis S, Vallance P, Smeeth L, Hingorani AD, MacAllister RJ (2005). Effect of inhibitors of the renin-angiotensin system and other antihypertensive drugs on renal outcomes: systematic review and meta-analysis.. The Lancet, 366(9502), 2026 - 2033. doi:10.1016/S0140-6736(05)67814-2
    • Clapp BR, Hirschfield GM, Storry C, Gallimore JR, Stidwill RP, Singer M, Deanfield JE, MacAllister RJ, Pepys MB, Vallance P, Hingorani AD (2005). Inflammation and endothelial function: direct vascular effects of human c reactive protein on NO bioavailability. Circulation, (111), 1530 - 1536.
    • Mittermayer F, Pleiner J, Schaller G, Zorn S, Namiranian K, Kapiotis S, Bartel G, Wolfrum M, BrĂ¼gel M, Thiery J, Macallister RJ, Wolzt M (2005). Tetrahydrobiopterin corrects Escherichia coli endotoxin-induced endothelial dysfunction.. Am J Physiol Heart Circ Physiol, 289(4), H1752 - H1757. doi:10.1152/ajpheart.00057.2005
    • Clapp BR, Hirschfield GM, Storry C, Gallimore JR, Stidwill RP, Singer M, Deanfield JE, MacAllister RJ, Pepys MB, Vallance P, Hingorani AD (2005). Inflammation and endothelial function: direct vascular effects of human C-reactive protein on nitric oxide bioavailability. Circulation, 111(12), 1530 - 1536. doi:10.1161/01.CIR.0000159336.31613.31

    2004

    • MacAllister R, Hingorani AD, Casas JP (2004). Ximelagatran or warfarin in atrial fibrillation?. , 363, 735 - 736.
    • Clapp BR, Hingorani AD, Kharbanda RK, Mohamed-Ali V, Stephens JW, Vallance P, MacAllister RJ (2004). Inflammation-induced endothelial dysfunction involves reduced nitric oxide bioavailability and increased oxidant stress.. Cardiovascular Research, 64(1), 172 - 178.
    • Ahluwalia A, MacAllister RJ, Hobbs AJ (2004). Vascular actions of natriuretic peptides. Cyclic GMP-dependent and -independent mechanisms.. Basic Research in Cardiology, 99(2), 83 - 89.
    • Broadhead MW, Kharbanda RK, Peters MJ, MacAllister RJ (2004). KATP channel activation induces ischemic preconditioning of the endothelium in humans in vivo.. Circulation, 110(15), 2077 - 2082. doi:10.1161/01.CIR.0000144304.91010.F0

    2003

    • Pleiner J, Mittermayer F, Schaller G, Marsik C, MacAllister RJ, Wolzt M (2003). Inflammation-induced vasoconstrictor hyporeactivity is caused by oxidative stress. Journal of the American College of Cardiology, 42(9), 1656 - 1662.
    • Cross JM, MacAllister RJ, Woolfson RG (2003). Vitamin C in renal failure--pro- or antioxidant?. Kidney International, 64(4), 1531 - 1532.
    • Chauhan S, Rahman A, Nilsson H, Clapp L, MacAllister R, Ahluwalia A (2003). NO contributes to EDHF-like responses in rat small arteries: a role for NO stores. Cardiovascular Research, 57(1), 207 - 216.
    • Cross JM, Donald AE, Nuttall SL, Deanfield JE, Woolfson RG, MacAllister RJ (2003). Vitamin C improves resistance but not conduit artery endothelial function in patients with chronic renal failure. Kidney International, 63(4), 1433 - 1442.
    • MacAllister R (2003). Combined salmeterol and fluticasone for COPD. The Lancet, 361(9369), 1651 - 1653.
    • Kharbanda RK, Hoschtitzky A, Vogel M, MacAllister R, Mortensen UM, Kristiansen S, Schmidt M, Sorensen KE, White PA, Redington A (2003). Transient limb ischemia induces remote ischemic preconditioning in vivo - Response. CIRCULATION, 107(24), E218 - E219.
    • Achan V, Broadhead M, Malaki M, Whitley G, Leiper J, MacAllister R, Vallance P (2003). Asymmetric dimethylarginine causes hypertension and cardiac dysfunction in humans and is actively metabolized by dimethylarginine dimethylaminohydrolase. ARTERIOSCL THROM VAS, 23(8), 1455 - 1459. doi:10.1161/01.ATV.0000081742.92006.59
    • Chauhan SD, Seggara G, Vo PA, MacAllister RJ, Hobbs AJ, Ahluwalia A (2003). Protection against lipopolysaccharide-induced endothelial dysfunction in resistance and conduit vasculature of iNOS knockout mice. The FASEB Journal, 17(6), 773 - 775.
    • Madhani M, Scotland RS, MacAllister RJ, Hobbs AJ (2003). Vascular natriuretic peptide receptor-linked particulate guanylate cyclases are modulated by nitric oxide-cyclic GMP signalling. British Journal of Pharmacology, 139(7), 1289 - 1296.

    2002

    • Pleiner J, Mittermayer F, Schaller G, MacAllister RJ, Wolzt M (2002). High doses of vitamin C reverse Escherichia coli endotoxin-induced hyporeactivity to acetylcholine in the human forearm. Circulation, 106(12), 1460 - 1464.
    • (2002). Prevention of inflammation-induced endothelial dysfunction - A novel vasculo-protective action of aspirin. Circulation, 105(22), 2600 - 2604. doi:10.1161/01.CIR.0000017863.52347.6C
    • Singh N, Prasad S, Singer DRJ, MacAllister RJ (2002). Ageing is associated with oxide and prostanoid impairment of nitric dilator pathways in the human forearm. CLIN SCI, 102(5), 595 - 600.
    • Chan NN, Vallance P, Colhoun HM, MacAllister RJ, Hingorani AD, Conway GS (2002). The effects of hormone replacement therapy on endothelial function in women with Turner's syndrome. Clinical Endocrinology, 56(5), 615 - 620.
    • Singh N, Graves J, Taylor PD, MacAllister RJ, Singer DR (2002). Effects of a 'healthy' diet and of acute and long-term vitamin C on vascular function in healthy older subjects. Cardiovascular Research, 56(1), 118 - 125.
    • Kharbanda RK, Mortensen UM, White PA, Kristiansen SB, Schmidt MR, Hoschtitzky JA, Vogel M, Sorensen K, Redington AN, MacAllister R (2002). Transient limb ischemia induces remote ischemic preconditioning in vivo. Circulation, 106(23), 2881 - 2883. doi:10.1161/01.CIR.0000043806.51912.9B

    2001

    • Kharbanda R, Walton B, Hingorani A, Macallister R, Vallance P (2001). High dose systemic aspirin protects from inflammatory endothelial dysfunction in humans in vivo.. CIRCULATION, 104(17), 152 - 153.
    • Clapp B, Macallister R, Kharbanda R, Hingorani A, Vallance P (2001). Inflammation impairs both basal and stimulated nitric oxide mediated vasodilatation. CIRCULATION, 104(17), 152 - 152.
    • Cross JM, Donald AE, Kharbanda R, Deanfield JE, Woolfson RG, MacAllister RJ (2001). Acute administration of L-arginine does not improve arterial endothelial function in chronic renal failure. Kidney International, 60(6), 2318 - 2323.
    • Hussain MB, MacAllister RJ, Hobbs AJ (2001). Reciprocal regulation of cGMP-mediated vasorelaxation by soluble and particulate guanylate cyclases. American Journal of Physiology - Heart and Circulatory Physiology, 280(3), H1151 - H1159.
    • Mullen MJ, Kharbanda RK, Cross J, Donald AE, Taylor M, Vallance P, Deanfield JE, MacAllister RJ (2001). Heterogenous nature of flow-mediated dilatation in human conduit arteries in vivo: relevance to endothelial dysfunction in hypercholesterolemia. Circulation Research, 88(2), 145 - 151.
    • Chan N, MacAllister R, Colhoun H, Vallance P, Hingorani A (2001). Changes in endothelium-dependent vasodilation and co-adrenergic responses in resistance vessels during the menstrual cycle in healthy women. Journal of Clinical Endocrinology and Metabolism, 86, 6 - .
    • Cross JM, Donald A, Vallance PJ, Deanfield JE, Woolfson RG, MacAllister RJ (2001). Dialysis improves endothelial function in humans. Nephrology Dialysis Transplantation, 16(9), 1823 - 1829.
    • Kharbanda RK, Peters M, Walton B, Kattenhorn M, Mullen M, Klein N, Vallance P, Deanfield J, MacAllister R (2001). Ischemic preconditioning prevents endothelial injury and systemic neutrophil activation during ischemia-reperfusion in humans in vivo. Circulation, 103(12), 1624 - 1630.
    • Chan NN, MacAllister RJ, Colhoun HM, Vallance P, Hingorani AD (2001). Changes in endothelium-dependent vasodilatation and alpha-adrenergic responses in resistance vessels during the menstrual cycle in healthy women. Journal of Clinical Endocrinology and Metabolism, 86(6), 2499 - 2504.

    2000

    • Singh N, Graves J, MacAllister R, Singer D (2000). Vitamin C and endothelial function in healthy older subjects. HYPERTENSION, 36(4), 659 - 659.
    • Singh N, Macallister RJ, Graves JE, Singer DRJ (2000). Cardiovascular risk and vascular function in healthy older subjects. CIRCULATION, 102(18), 326 - 326.
    • Singh N, Graves JE, Macallister RJ, Singer DRJ (2000). A 'healthy diet' but not long-term vitamin C as supplements improves both endothelium-dependent and endothelium-independent vasodilator function in healthy older subjects. CIRCULATION, 102(18), 55 - 55.
    • Hussain MB, MacAllister RJ, Hobbs AJ (2000). Regulation of cGMP-mediated vasorelaxation in mouse thoracic aorta: Interactions of the soluble and particulate guanylate cyclases. BRIT J PHARMACOL, 129, - .
    • MacAllister RJ (2000). Arginine and nitrate tolerance. British Journal of Pharmacology, 130(2), 209 - 210.
    • Barba G, Vallance PJ, Strazzullo P, MacAllister RJ (2000). Effects of sodium intake on the pressor and renal responses to nitric oxide synthesis inhibition in normotensive individuals with different sodium sensitivity. Journal of Hypertension, 18(5), 615 - 621.
    • Hingorani AD, Cross J, Kharbanda RK, Mullen MJ, Bhagat K, Taylor M, Donald AE, Palacios M, Griffin GE, Deanfield JE, MacAllister RJ, Vallance P (2000). Acute systemic inflammation impairs endothelium-dependent dilatation in humans. Circulation, 102(9), 994 - 999.
    • Chan NN, Vallance PJ, Macallister RJ, Hingorani AD, Colhoun HM (2000). Impaired nitric oxide response in resistance vessels in human type 1 diabetes in vivo. CIRCULATION, 102(18), 326 - 326.
    • Kharbanda RK, Walton BI, Peters MJ, Kattenhorn M, Mullen MJ, Klein NJ, Vallance PJ, Deanfield JE, Macallister RJ (2000). Ischemic preconditioning prevents endothelial injury and immune cell activation during ischemia-reperfusion in humans in vivo.. CIRCULATION, 102(18), 119 - 119.

    1999

    • Wolzt M, MacAllister RJ, Davis D, Feelisch M, Moncada S, Vallance P, Hobbs AJ (1999). Biochemical characterization of S-nitrosohaemoglobin: mechanisms underlying synthesis, NO release, and biological activity. Journal of Biological Chemistry, 274, 28983 - 28990.
    • Kharbanda RK, Mullen MJ, Cross JM, Deanfield JE, Vallance P, MacAllister RJ (1999). Flow-mediated dilatation of human conduit arteries to sustained flow is presented in hypercholesterolaemia. CIRCULATION, 100(18), 49 - 49.
    • Leiper JM, Santa Maria J, Chubb A, MacAllister RJ, Charles IG, Whitley GS, Vallance P (1999). Identification of two human dimethylarginine dimethylaminohydrolases with distinct tissue distributions and homology with microbial arginine deiminases. Biochemical Journal, 343 Pt, 209 - 214.
    • Hussain MB, Hobbs AJ, MacAllister RJ (1999). Autoregulation of nitric oxide-soluble guanylate cyclase-cyclic GMP signalling in mouse thoracic aorta. British Journal of Pharmacology, 128(5), 1082 - 1088.
    • Mullen MJ, Kharbanda RK, Donald AE, Taylor M, Deanfield JE, Vallance P, MacAllister RJ (1999). Flow-mediated dilatation of human conduit arteries to sustained flow is nitric oxide independent. CIRCULATION, 100(18), 48 - 49.
    • Barba G, Mullen MJ, Donald A, MacAllister RJ (1999). Determinants of the response of human blood vessels to nitric oxide donors in vivo. The Journal of Pharmacology and Experimental Therapeutics, 289(3), 1662 - 1668.
    • Hingorani AD, Bhagat K, Palacios M, Griffin GE, MacAllister RJ, Vallance P (1999). Acute systemic inflammation impairs endothelium-dependent dilatation in humans. BRIT J PHARMACOL, 126, U31 - U31.
    • Hussain MB, Hobbs AJ, MacAllister RJ (1999). Enhanced sensitivity of the soluble guanylate cyclase/cyclic GMP system in the eNOS knockout mouse. BRIT J PHARMACOL, 126, U41 - U41.
    • Graves JE, Taylor PD, Antonios TFT, MacAllister RJ, Singer DRJ (1999). Vascular reactivity of isolated subcutaneous fat resistance arteries from older people. BRIT J PHARMACOL, 126, - .
    • Singh N, Graves JE, MacAllister RJ, Singer DRJ (1999). Vitamin C does not alter endothelium-dependent dilatation in the forearm of elderly humans. BRIT J PHARMACOL, 126, - .

    1998

    • MacAllister RJ, Vallance P (1998). Endogenous inhibitors of nitric oxide synthesis: how important are they?. EXP NEPHROL, 6(3), 195 - 199.

    1997

    • Berrazueta JR, Bhagat K, Vallance P, MacAllister RJ (1997). Dose- and time-dependency of the dilator effects of the endothelin antagonist, BQ-123, in the human forearm. BR J CLIN PHARMACOL, 44, 569 - 571.
    • MacAllister R, Vallance P (1997). Endogenous inhibitors of nitric oxide synthesis. In Andreucci V, Fine L (Ed.), Yearbook in Nephrology (pp. 35 - 39). : Oxford University Press.

    1996

    • MacAllister RJ, Vallance P (1996). Systemic vascular adaptation to increases in blood volume: the role of the blood-vessel wall.. Nephrol Dial Transplant, 11(2), 231 - 234.
    • MacAllister RJ, Rambausek MH, Vallance P, Williams D, Hoffmann KH, Ritz E (1996). Concentration of dimethyl-L-arginine in the plasma of patients with end-stage renal failure. NEPHROL DIAL TRANSPL, 11(12), 2449 - 2452.
    • MacAllister RJ, Parry H, Kimoto M, Ogawa T, Russell RJ, Hodson H, Whitley GS, Vallance P (1996). Regulation of nitric oxide synthesis by dimethylarginine dimethylaminohydrolase.. Br J Pharmacol, 119(8), 1533 - 1540.

    1995

    • Vallance P, Patton S, Bhagat K, MacAllister R, Radomski M, Moncada S, Malinski T (1995). Direct measurement of nitric oxide in human beings.. Lancet, 346(8968), 153 - 154.
    • MacAllister RJ, Calver AL, Riezebos J, Collier J, Vallance P (1995). Relative potency and arteriovenous selectivity of nitrovasodilators on human blood vessels: an insight into the targeting of nitric oxide delivery.. J Pharmacol Exp Ther, 273(1), 154 - 160.
    • Arese M, Strasly M, Ruva C, Costamagna C, Ghigo D, MacAllister R, Verzetti G, Tetta C, Bosia A, Bussolino F (1995). Regulation of nitric oxide synthesis in uraemia.. Nephrol Dial Transplant, 10(8), 1386 - 1397.
    • Davies G, MacAllister RJ, Bogle RG, Vallance P (1995). Effect of diadenosine phosphates on human umbilical vessels: novel platelet-derived vasoconstrictors.. Br J Clin Pharmacol, 40(2), 170 - 172.
    • MacAllister RJ, Calver AL, Collier J, Edwards CM, Herreros B, Nussey SS, Vallance P (1995). Vascular and hormonal responses to arginine: provision of substrate for nitric oxide or non-specific effect?. Clin Sci (Lond), 89(2), 183 - 190.
    • BOGLE RG, MACALLISTER RJ, WHITLEY GS, VALLANCE P (1995). INDUCTION OF N-G-MONOMETHYL-L-ARGININE UPTAKE - A MECHANISM FOR DIFFERENTIAL INHIBITION OF NO SYNTHASES. AM J PHYSIOL-CELL PH, 38(3), C750 - C756.

    1994

    • MacAllister R, Vallance P (1994). Nitric oxide in essential and renal hypertension.. J Am Soc Nephrol, 5(4), 1057 - 1065.
    • MacAllister RJ, Whitley GS, Vallance P (1994). Effects of guanidino and uremic compounds on nitric oxide pathways.. Kidney Int, 45(3), 737 - 742.
    • MacAllister RJ, Fickling SA, Whitley GS, Vallance P (1994). Metabolism of methylarginines by human vasculature; implications for the regulation of nitric oxide synthesis.. Br J Pharmacol, 112(1), 43 - 48.
    • de Belder AJ, MacAllister R, Radomski MW, Moncada S, Vallance PJ (1994). Effects of S-nitroso-glutathione in the human forearm circulation: evidence for selective inhibition of platelet activation.. Cardiovasc Res, 28(5), 691 - 694.

    1993

    • Griffiths MJ, Messent M, MacAllister RJ, Evans TW (1993). Aminoguanidine selectively inhibits inducible nitric oxide synthase.. Br J Pharmacol, 110(3), 963 - 968.
    • Macallister RJ, Morgan SH (1993). Fallopian tube capture of chronic peritoneal dialysis catheters.. Perit Dial Int, 13(1), 74 - 76.