Prof Mark Marsh

Photo

Personal Profile

Name: Mark Marsh Email: m.marsh@ucl.ac.uk
Title: Prof Tel: 0044 20 7679 7807
Department: MRC/UCL Lab for Molecular Cell Bio Fax: 0044 20 7679 7805
Position: Director Address: MRC-LMCB, UCL, Gower Street, London, WC1E 6BT
Research Domain: Basic Life Sciences, Global Health, Infection, Immunology & Inflammation, Personalised Medicine Web Page: Personal Web Page

Profile

Research Description

Our research is currently focused on two areas:

* Understanding the mechanisms of assembly of HIV and how this might be used to understand and combat pathogenesis.

* Understanding the molecular and cellular mechanisms that control the cell surface expression of the receptors for HIV and related viruses. Enveloped virus entry and egress is tightly linked to cellular membranes. Understanding the cellular and molecular mechanisms underlying these events informs us not only of the viruses themselves, but also of some basic properties of these membrane systems.


Research Activities

Investigating the molecular basis of frontotemporal dementia

Education Description

UCL Collaborators

Prof Clare Futter; Prof Sebastian Brandner; Dr Robin Ketteler; Dr Adrian Isaacs; Prof Tamas Revesz; Prof Martin Rossor; Prof Nick Fox

External Collaborators

Prof Terje Johansen; Dr Anne Simonsen; Freja Consortium; Prof Christine Van Broeckhoven

Publications

    2014

    • Vermeire K, Bell TW, Van Puyenbroeck V, Giraut A, Noppen S, Liekens S, Schols D, Hartmann E, Kalies KU, Marsh M (2014). Signal peptide-binding drug as a selective inhibitor of co-translational protein translocation.. PLoS Biol, 12(12), e1002011 - . doi:10.1371/journal.pbio.1002011
    • Grove J, Metcalf DJ, Knight AE, Wavre-Shapton ST, Sun T, Protonotarios ED, Griffin LD, Lippincott-Schwartz J, Marsh M (2014). Flat clathrin lattices: stable features of the plasma membrane.. Mol Biol Cell, 25(22), 3581 - 3594. doi:10.1091/mbc.E14-06-1154
    • Smith S, Weston S, Kellam P, Marsh M (2014). IFITM proteins-cellular inhibitors of viral entry.. Curr Opin Virol, 4, 71 - 77. doi:10.1016/j.coviro.2013.11.004
    • Giese S, Marsh M (2014). Tetherin can restrict cell-free and cell-cell transmission of HIV from primary macrophages to T cells.. PLoS Pathog, 10(7), e1004189 - . doi:10.1371/journal.ppat.1004189
    • Marsh M, McKeating JA (2014). Editorial overview - Virus entry: Towards reality - Refining models of virus entry. Current Opinion in Virology, 4, - . doi:10.1016/j.coviro.2014.01.001
    • Weston S, Czieso S, White IJ, Smith SE, Kellam P, Marsh M (2014). A membrane topology model for human interferon inducible transmembrane protein 1.. PLoS One, 9(8), e104341 - . doi:10.1371/journal.pone.0104341

    2013

    • Blondeau C, Pelchen-Matthews A, Mlcochova P, Marsh M, Milne RS, Towers GJ (2013). Tetherin restricts herpes simplex virus 1 and is antagonized by glycoprotein M.. J Virol, 87(24), 13124 - 13133. doi:10.1128/JVI.02250-13
    • Tippett E, Cameron PU, Crowe SM, Marsh M (2013). Characterization of tetraspanins CD9, CD53, CD63, and CD81 in monocytes and. Journal of Leukocyte Biology, 93(6), 913 - 920. doi:10.1189/jlb.0812391
    • Tippett E, Cameron PU, Marsh M, Crowe SM (2013). Characterization of tetraspanins CD9, CD53, CD63, and CD81 in monocytes and macrophages in HIV-1 infection. JOURNAL OF LEUKOCYTE BIOLOGY, 93(6), 913 - 920. doi:10.1189/jlb.0812391
    • Mlcochova P, Pelchen-Matthews A, Marsh M (2013). Organization and regulation of intracellular plasma membrane-connected HIV-1 assembly compartments in macrophages.. BMC Biol, 11, 89 - . doi:10.1186/1741-7007-11-89

    2012

    • Snijder B, Liberali P, Mench K, Wolfrum N, Jurgeit A, Greber U, Pelkmans L, Sacher R, Rämö P, Lamparter D, Burleigh L, Amara A, Scott CC, Gruenberg J, Verheije MH, De Haan CAM, Rottier PJM, Mercer J, Moese S, Heger T, Balistreri G, Schelhaas M, Helenius A, Theusner K, Sodeik B, Marsh M, Marjomäki V, Hyypiä T (2012). Single-cell analysis of population context advances RNAi screening at multiple levels. Molecular Systems Biology, 8, - . doi:10.1038/msb.2012.9
    • Henry AG, Hislop JN, Grove J, Thorn K, Marsh M, von Zastrow M (2012). Regulation of endocytic clathrin dynamics by cargo ubiquitination. Developmental Cell, 23, 519 - 532.
    • Pelchen-Matthews A, Giese S, Mlcochova P, Turner J, Marsh M (2012). ss 2 Integrin Adhesion Complexes Maintain the Integrity of HIV-1 Assembly Compartments in Primary Macrophages. TRAFFIC, 13(2), 273 - 291. doi:10.1111/j.1600-0854.2011.01306.x

    2011

    • Caillet M, Janvier K, Delcroix-Genête D, Camus G, Berlioz-Torrent C, Pelchen-Matthews A, Marsh M (2011). Rab7A is required for efficient production of infectious HIV-1. PLoS Pathogens, 7(11), - . doi:10.1371/journal.ppat.1002347
    • Henry AG, White IJ, Marsh M, von Zastrow M, Hislop JN (2011). The role of ubiquitination in lysosomal trafficking of δ-opioid receptors.. Traffic, 12(2), 170 - 184. doi:10.1111/j.1600-0854.2010.01145.x
    • Grove J, Marsh M (2011). The cell biology of receptor-mediated virus entry.. J Cell Biol, 195(7), 1071 - 1082. doi:10.1083/jcb.201108131
    • Janvier K, Pelchen-Matthews A, Renaud JB, Caillet M, Marsh M, Berlioz-Torrent C (2011). The ESCRT-0 component HRS is required for HIV-1 Vpu mediated BST2/Tetherin down regulation. , 7, e1001265 - .
    • Vermeire K, Schols D, Bell TW, Marsh M (2011). Identification of a specific inhibitor of CD4 translocation: A novel approach to regulating the expression of the cellular HIV receptor.. , Submitted, - .
    • Alonso R, Mazzeo C, Carmen Rodríguez M, Marsh M, Fraile-Ramos A, Calvo V, Avila-Flores A, Mérida I, Izquierdo M (2011). Diacylglycerol Kinase α regulates the formation and polarization of mature multivesicular bodies involved in the secretion of Fas ligand-containing exosomes in T lymphocytes. , , - .

    2010

    • Brodsky FM, Marsh M (2010). Life History of the Journal TRAFFIC, Celebrating Ten Years of Publication. Traffic, 11, 1 - 3.

    2009

    • Azevedo C, Burton A, Ruiz-Mateos E, Marsh M, Saiardi A (2009). IP7-mediated pyro-phosphorylation of AP3B1 regulates HIV-1 Gag release. , 106, 21161 - 21166.
    • Theusner K, Pelchen-Matthews A, Marsh M (2009). Human Immunodeficiency Virus infection of macrophages - assembly and transmission to T lymphocytes. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 39, 38 - 38.
    • Gupta RK, Mlcochova P, Pelchen-Matthews A, Petit SJ, Mattiuzzo G, Pillay D, Takeuchi Y, Marsh M, Towers GJ (2009). Simian immunodeficiency virus envelope glycoprotein counteracts tetherin/BST-2/CD317 by intracellular sequestration.. Proc Natl Acad Sci U S A, 106(49), 20889 - 20894. doi:10.1073/pnas.0907075106
    • Kershaw T, Wavre-Shapton ST, Signoret N, Marsh M (2009). Analysis of chemokine receptor endocytosis and intracellular trafficking.. Methods Enzymol, 460, 357 - 377. doi:10.1016/S0076-6879(09)05218-5
    • Gupta RK, Mlcochova P, Pelchen-Matthews A, Petit SJ, Mattiuzzo G, Pillay D, Takeuchi Y, Marsh M, Towers GJ (2009). Simian Immunodeficiency Virus envelope glycoprotein counteracts tetherin/BST-2/CD317 by intracellular sequestration. , 106, 20889 - 20894.
    • Marsh M, Theusner K, Pelchen-Matthews A (2009). HIV assembly and budding in macrophages. , 37, 185 - 189.
    • Smith AM, Rahman FZ, Hayee BH, Graham SJ, Marks DJB, Sewell GW, Palmer CD, Wilde J, Foxwell BMJ, Gloger IS, Sweeting TJ, Marsh M, Walker AP, Bloom SL, Segal AW (2009). Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease.. Journal of Experimental Medicine, 206(9), 1883 - 1897.
    • Azevedo C, Burton A, Ruiz-Mateos E, Marsh M, Saiardi A (2009). Inositol pyrophosphate mediated pyrophosphorylation of AP3B1 regulates HIV-1 Gag release.. Proc Natl Acad Sci U S A, 106(50), 21161 - 21166. doi:10.1073/pnas.0909176106

    2008

    • Ruiz-Mateos E, Pelchen-Matthews A, Deneka M, Marsh M (2008). CD63 is not required for production of infectious human immunodeficiency virus type 1 in human macrophages. Journal of Virology, 82(10), 4751 - 4761.
    • Marsh M, van Meer G (2008). Cell biology. No ESCRTs for exosomes.. Science, 319(5867), 1191 - 1192. doi:10.1126/science.1155750
    • Forzan M, Marsh M, Roy P (2008). Bluetongue virus entry into cells (vol 81, pg 4819, 2007). JOURNAL OF VIROLOGY, 82(3), 1626 - 1626. doi:10.1128/JVI.02405-07

    2007

    • Martin-Serrano J, Marsh M (2007). ALIX Catches HIV. Cell Host and Microbe, 1(1), 5 - 7. doi:10.1016/j.chom.2007.02.006
    • Forzan M, Marsh M, Roy P (2007). Bluetongue virus entry into cells.. Journal of Virology, 81, 4819 - 4827.
    • Deneka M, Pelchen-Matthews A, Byland R, Ruiz-Mateos E, Marsh M (2007). In macrophages, HIV-1 assembles into an intracellular plasma membrane domain containing the tetraspanins CD81, CD9, and CD53.. J Cell Biol, 177(2), 329 - 341. doi:10.1083/jcb.200609050
    • Fraile-Ramos A, Pelchen-Matthews A, Risco C, Rejas MT, Emery VC, Hassan-Walker AF, Esteban M, Marsh M (2007). The ESCRT machinery is not required for human cytomegalovirus envelopment. CELL MICROBIOL, 9(12), 2955 - 2967. doi:10.1111/j.1462-5822.2007.01024
    • Byland R, Vance PJ, Hoxie JA, Marsh M (2007). A conserved dileucine motif mediates clathrin and AP-2-dependent endocytosis of the HIV-1 envelope protein.. Molecular Biology of the Cell, 18(2), 414 - 425.
    • Pelchen-Matthews A, Marsh M (2007). Electron microscopy analysis of viral morphogenesis.. Methods Cell Biol, 79, 515 - 542. doi:10.1016/S0091-679X(06)79020-3
    • Fraile-Ramos A, Pelchen-Matthews A, Risco C, Rejas MT, Emery VC, Hassan-Walker AF, Esteban M, Marsh M (2007). The ESCRT machinery is not required for human cytomegalovirus envelopment.. Cellular Microbiology, 9(12), 2955 - 2967. doi:10.1111/j.1462-5822.2007.01024.x

    2006

    • Marsh M (2006). Endosomes - key components in viral entry and replication. In Dikic I (Ed.), Endosomes (pp. 131 - 144). : Landes Bioscience.
    • Marsh M (2006). Endosomes - key components in viral entry and replication. In Dikic I (Ed.), Endosomes (pp. 132 - 144). : Landes Bioscience.
    • Pelchen-Matthews and Marsh M (2006). EM analysis of viral morphogenesis. In Mcintosh RJ (Ed.), Methods in Cell Biology vol Cellular Electron Microscopy (pp. - ). : Elsevier Inc.
    • Marsh M, Helenius A (2006). Virus entry: open sesame.. Cell, 124(4), 729 - 740. doi:10.1016/j.cell.2006.02.007

    2005

    • Marsh M (2005). Cell biology of virus replication. In P Cossart PN, Rappuoli SNAR (Ed.), Cellular Microbiology (pp. 517 - 542). : ASM Press.
    • Byland RAM, M (2005). Trafficking of viral membrane proteins.. In Marsh M (Ed.), Membrane Trafficking in Viral Replication (pp. 219 - 254). : Springer.
    • Marsh M (2005). Membrane trafficking and viral replication.
    • Kramer B, A Pelchen-Matthews MD, andMarsh M (2005). HIV interaction with endosomes in macrophages and dendritic cells. Blood Cells, Molecules, and Diseases, (35), 136 - 142.
    • Garcia E, Pion M, Pelchen-Matthews A, Collinson L, Arrighi JF, Blot G, Leuba F, Escola JM, Demaurex N, Marsh M, Piguet V (2005). HIV-1 trafficking to the dendritic cell-T-cell infectious synapse uses a pathway of tetraspanin sorting to the immunological synapse. TRAFFIC, 6(6), 488 - 501. doi:10.1111/j.1600-0854.2005.00293.x
    • Kramer B, Pelchen-Matthews A, Deneka M, Garcia E, Piguet V, Marsh M (2005). HIV interaction with endosomes in macrophages and dendritic cells.. Blood Cells Mol Dis, 35(2), 136 - 142. doi:10.1016/j.bcmd.2005.06.006
    • Peter M, Ameer-Beg SM, Hughes MKY, Keppler MD, Prag S, Ng T, Vojnovic B, Marsh M (2005). Multiphoton-FLIM quantification of the EGFP-mRFP1 FRET pair for localization of membrane receptor-kinase interactions. Biophysical Journal, 88(2), 1224 - 1237. doi:10.1529/biophysj.104.050153
    • Signoret N, Hewlett L, Wavre S, Pelchen-Matthews A, Oppermann M, Marsh M (2005). Agonist-induced endocytosis of chemokine receptor 5 (CCR5) occurs by clathrin-mediated endocytosis. Molecular Biology of the Cell, (16), 902 - 917.
    • Signoret N, Hewlett L, Wavre S, Pelchen-Matthews A, Oppermann M, Marsh M (2005). Agonist-induced endocytosis of CC chemokine receptor 5 is clathrin dependent.. Mol Biol Cell, 16(2), 902 - 917. doi:10.1091/mbc.E04-08-0687
    • Garcia E, Pion M, Pelchen-Matthews A, Collinson L, Arrighi JF, Marsh M, Piguet V (2005). Trafficking of HIV-1 to the dendritic cell-T cell infectious synapse uses DC-SIGN and the pathway of tetraspanin sorting to the immunological synapse.

    2004

    • Pelchen-Matthews A, Raposo G, Marsh M (2004). Endosomes, exosomes and Trojan viruses.. Trends Microbiol, 12(7), 310 - 316. doi:10.1016/j.tim.2004.05.004
    • Garcia E, Pion M, Pelchen-Matthews A, Collinson L, Arrighi J-F, Blot B, Leuba F, Escola J-M, Demaurex N, Marsh M, Piguet V (2004). HIV-1 trafficking to the dendritic cell-T-cell infectious synapse uses a pathway of tetraspanin sorting to the immunological synapse. Traffic, (6), 488 - 501.
    • Signoret N, Christophe T, Oppermann MAM, M (2004). pH-independent endocytic of the chemokine receptor CCR5. Traffic, (5), 529 - 543.
    • Signoret N, Christophe T, Oppermann M, Marsh M (2004). pH-independent endocytic cycling of the chemokine receptor CCR5.. Traffic, 5(7), 529 - 543.
    • Marsh M, Signoret N, Wavre S, Fraile-Ramos A, Pelchen-Matthews A, Hewlett L (2004). Endocytosis of cellular and viral chemokine receptors.

    2003

    • Fraile-Ramos A, Kohout TA, Waldhoer M, Marsh M (2003). Endocytosis of the viral chemokine receptor US28 does not require beta-arrestins but is dependent on the clathrin-mediated pathway.. Traffic, 4(4), 243 - 253.
    • Marsh M, Thali M (2003). HIV's great escape. Nature Medicine, 9(10), 1262 - 1263. doi:10.1038/nm1003-1262
    • Pelchen-Matthews A, Kramer B, Marsh M (2003). Infectious HIV-1 assembles in late endosomes in primary macrophages.. J Cell Biol, 162(3), 443 - 455. doi:10.1083/jcb.200304008
    • Bijlmakers M-J, Marsh M (2003). The on-off story of protein palmitoylation. Trends in Cell Biology, 13(1), 32 - 42. doi:10.1016/S0962-8924(02)00008-9
    • Fraile-Ramos A, Waldhoer M, Schwartz TW, Marsh M (2003). Endocytosis of the Viral Chemokine Receptor US28 Does Not Require beta-Arrestins. Traffic, 4, 243 - 253.

    2002

    • Fraile-Ramos A, Pelchen-Matthews A, Kledal TN, Browne H, Schwartz TW, Marsh M (2002). Localization of HCMV UL33 and US27 in endocytic compartments and viral membranes.. Traffic, 3(3), 218 - 232.
    • Martini L, Hastrup H, Holst B, Fraile-Ramos A, Marsh M, Schwartz TW (2002). NK1 receptor fused to beta-arrestin displays a mono-component, high affinity molecular phenotype. Molecular Pharmacology, 62, 30 - 37.
    • Marsh M, Pelchen-Matthews A, Kramer B, Fraile-Ramos A (2002). Virus assembly in the endocytic pathway.
    • Fraile-Ramos A, Marsh M (2002). Endocytosis of the viral chemokine receptor US28 does not require beta-arrestins.
    • Fraile-Ramos A, Pelchen-Matthews A, Kledal TN, Browne H, Schwartz TW, Marsh M (2002). Localization of human cytomegalovirus UL33 and US27 proteins in endocytic compartments and viral membranes. Traffic, 3, 218 - 232.

    2001

    • Russell DG, Marsh M (2001). Endocytosis in pathogen entry and replication. In Marsh M (Ed.), Endocytosis (pp. 247 - 280). : Oxford University Press.
    • (2001). Endocytosis.
    • Fultz PN, Vance PJ, Endres MJ, Tao B, Dvorin JD, Davis IC, Lifson JD, Montefiori DC, Marsh M, Malim MH, Hoxie JA (2001). In Vivo Attenuation of Simian Immunodeficiency Virus by Disruption of a Tyrosine-Dependent Sorting Signal in the Envelope Glycoprotein Cytoplasmic Tail. , 75, 278 - 291.
    • Marsh M (2001). An all too visible adversary. , 105, 317-318 Book review - .
    • Fraile-Ramos A, Kledal TN, Pelchen-Matthews A, Bowers K, Schwartz TW, Marsh M (2001). The human cytomegalovirus US28 protein is located in endocytic vesicles and undergoes constitutive endocytosis and recycling.. Mol Biol Cell, 12(6), 1737 - 1749.
    • Signoret N, Pelchen-Matthews A, Marsh M (2001). pH independent sorting and recycling of the chemokine receptor CCR5.
    • Marsh M (2001). An all too visible adversary (reviewing) The Invisible Enemy - Dorothy Crawford. Cell, 105, 317 - 318.

    2000

    • Marsh M, Pelchen-Matthews A (2000). Endocytosis in viral replication.. Traffic, 1(7), 525 - 532.
    • Signoret N, Pelchen-Matthews A, Mack M, Proudfoot AE, Marsh M (2000). Endocytosis and recycling of the HIV coreceptor CCR5.. J Cell Biol, 151(6), 1281 - 1294.
    • Marsh M, Signoret N, Pelchen-Matthews A (2000). Endocytosis and recycling of the HIV co-receptor CCR5.
    • Bijlmakers MJE, Marsh M (2000). Hsp90 is required for the synthesis and subsequent membrane-association, but not maintenance, of the Src-family kinase p56Lck. , 11, 1585 - 1595.
    • Bowers K, Pelchen-Matthews A, Höning S, Vance PJ, Creary L, Haggarty BS, Romano J, Ballensiefen W, Hoxie JA, Marsh M (2000). The simian immunodeficiency virus envelope glycoprotein contains multiple signals that regulate its cell surface expression and endocytosis.. Traffic, 1(8), 661 - 674.
    • Signoret N, Marsh M (2000). Analysis of chemokine receptor endocytosis and recycling.. Methods Mol Biol, 138, 197 - 207. doi:10.1385/1-59259-058-6:197
    • Marsh M (2000). Receptor-mediated endocytosis. In (Ed.), Encyclopaedia of Life Science (pp. - ). : Macmillan Reference Ltd..
    • Nobes C, Marsh M (2000). New roles for Cdc42 and Rac in antigen uptake?. Current Biology, 10(20), R739 - R741.
    • Nobes C, Marsh M (2000). Dendritic cells: new roles for Cdc42 and Rac in antigen uptake?. Curr Biol, 10(20), R739 - R741.
    • Fraile-Ramos A, Kledal TN, Schwartz TW, Marsh M (2000). The human cytomegalovirus chemokine receptor US28 undergoes constitutive endocytosis and recycling. MOLECULAR BIOLOGY OF THE CELL, 11, 503A - 503A.
    • Bijlmakers MJ, Marsh M (2000). Hsp90 is essential for the synthesis and subsequent membrane association, but not the maintenance, of the Src-kinase p56(lck).. Mol Biol Cell, 11(5), 1585 - 1595.

    1999

    • Lord JM, Marsh M (1999). Endocytosis. In Creighton TE (Ed.), Encyclopaedia of Molecular Biology (pp. 809 - 812). : John Wiley and Sons, Inc..
    • Pelchen-Matthews A, Signoret N, Klasse PJ, Fraile-Ramos A, Marsh M (1999). Chemokine receptor trafficking and viral replication.. Immunol Rev, 168, 33 - 49.
    • Lord JM, Marsh M (1999). Pinocytosis. In Creighton TE (Ed.), Encyclopaedia of Molecular Biology (pp. 1860 - 1861). : John Wiley and Sons, Inc..
    • Lord JM, Marsh M (1999). Macropinosomes. In Creighton TE (Ed.), Encyclopaedia of Molecular Biology (pp. 1430 - ). : John Wiley and Sons, Inc..
    • Lord JM, Marsh M (1999). Phagocytosis. In Creighton TE (Ed.), Encyclopaedia of Molecular Biology (pp. 1822 - ). : John Wiley and Sons, Inc..
    • Pitcher C, Hoening S, Fingerhut A, Bowers K, Marsh M (1999). CD4 endocytosis and adaptor complex binding requires activation of the CD4 endocytosis signal by serine phosphorylation. , 10, 677 - 691.
    • Klasse PJ, Rosenkilde MM, Signoret N, Pelchen-Matthews A, Schwartz TW, Marsh M (1999). CD4-Chemokine receptor hybrids in human immunodeficiency virus type 1 infection.. J Virol, 73(9), 7453 - 7466.
    • Marsh M (1999). A new Nature. Trends in Cell Biology, 9(421), - .
    • Marsh M, McMahon HT (1999). The structural era of endocytosis.. Science, 285(5425), 215 - 220.
    • Guinamard R, Signoret N, Marsh M, Kurosaki T, Ravetch JV (1999). BCR engagement inhibits SDF-1a chemotaxis via PKC induced internalization of CXCR4. Journal of Experimental Medicine, 189, 1461 - 1466.
    • Pitcher C, Höning S, Fingerhut A, Bowers K, Marsh M (1999). Cluster of differentiation antigen 4 (CD4) endocytosis and adaptor complex binding require activation of the CD4 endocytosis signal by serine phosphorylation.. Mol Biol Cell, 10(3), 677 - 691.
    • Guinamard R, Ravetch JV, Signoret N, Marsh M, Masamichi I, Kurosaki T (1999). B cell antigen receptor engagement inhibits stromal cell-derived factor (SDF)-1α chemotaxis and promotes protein kinase C (PKC)-induced internalization of CXCR4. Journal of Experimental Medicine, 189(9), 1461 - 1466. doi:10.1084/jem.189.9.1461
    • Lord JM, Marsh M (1999). Endocytosis. In (Ed.), Encyclopedia of Molecular Biology (pp. - ). : Wiley-VCH Publishers.
    • Signoret N, Marsh M (1999). Analysis of chemokine receptor endocytosis and recycling. In Proudfoot AEI, Wells TNC, Power C (Ed.), Methods in Molecular Biology (pp. 195 - 208). : Humana Press Inc..
    • Bijlmakers MJ, Marsh M (1999). Trafficking of an acylated cytosolic protein: newly synthesized p56(lck) travels to the plasma membrane via the exocytic pathway.. J Cell Biol, 145(3), 457 - 468.
    • Lord JM, Marsh M (1999). Endosomes. In Creighton TE (Ed.), Encyclopaedia of Molecular Biology (pp. 818 - 819). : John Wiley and Sons, Inc..

    1998

    • Mack M, Luckow B, Nelson PJ, Schlöndorff D, Cihak J, Stangassinger M, Simmons G, Clapham PR, Signoret N, Marsh M, Borlat F, Wells TNC, Proudfoot AEI (1998). Aminooxypentane-RANTES induces CCR5 internalization but inhibits recycling: A novel inhibitory mechanism of HIV infectivity. Journal of Experimental Medicine, 187(8), 1215 - 1224. doi:10.1084/jem.187.8.1215
    • Klasse PJ, Bron R, Marsh M (1998). Mechanisms of enveloped virus entry into animal cells.. Adv Drug Deliv Rev, 34(1), 65 - 91.
    • Signoret N, Rosenkilde MM, Klasse PJ, Schwartz TW, Malim MH, Hoxie JA, Marsh M (1998). Differential regulation of CXCR4 and CCR5 endocytosis.. J Cell Sci, 111 ( Pt 18), 2819 - 2830.
    • Briant L, Robert-Hebmann V, Acquaviva C, Devaux C, Pelchen-Matthews A, Marsh M (1998). The protein tyrosine kinase p56(lck) is required for triggering NF-κB activation upon interaction of human immunodeficiency virus type 1 envelope glycoprotein gp120 with cell surface CD4. Journal of Virology, 72(7), 6207 - 6214.
    • Pelchen-Matthews A, da Silva RP, Bijlmakers MJ, Signoret N, Gordon S, Marsh M (1998). Lack of p56lck expression correlates with CD4 endocytosis in primary lymphoid and myeloid cells.. Eur J Immunol, 28(11), 3639 - 3647.
    • Mack M, Luckow B, Nelson PJ, Cihak J, Simmons G, Clapham PR, Signoret N, Marsh M, Borlat F, Stangassinger F, Wells TNC, Schlondorff D, Proudfoot AEI (1998). AOP-RANTES prevents CCR5 recycling: a novel inhibitory mechanism of HIV infectivity. Journal of Experimental Medicine, 187, 1215 - 1224.
    • Oldridge J, Marsh M (1998). Nef - An adaptor adaptor?. Trends in Cell Biology, 8(8), 302 - 305. doi:10.1016/S0962-8924(98)01318-X

    1997

    • McKnight A, Wilkinson D, Simmons G, Talbot S, Picard L, Ahuja M, Marsh M, Hoxie JA, Clapham PR (1997). Inhibition of Human Immunodeficiency virus fusion by a monoclonal antibody to a co-receptor (CXCR4) is both cell type and virus strain dependent.. , 72, 1692 - 1696.
    • Bron R, Klasse PJ, Wilkinson D, Clapham PR, Pelchen-Matthews A, Power C, Wells TNC, Kim J, Peiper SC, Hoxie JA, Marsh M (1997). Promiscuous use of CC and CXC chemokine receptors in cell-to-cell fusion mediated by an HIV-2ROD Envelope protein. , 71, 8405 - 8415.
    • Bron R, Klasse PJ, Wilkinson D, Clapham PR, Pelchen-Matthews A, Power C, Wells TN, Kim J, Peiper SC, Hoxie JA, Marsh M (1997). Promiscuous use of CC and CXC chemokine receptors in cell-to-cell fusion mediated by a human immunodeficiency virus type 2 envelope protein.. J Virol, 71(11), 8405 - 8415.
    • Bowers K, Pitcher C, Marsh M (1997). CD4: a co-receptor in the immune response and HIV infection.. Int J Biochem Cell Biol, 29(6), 871 - 875.
    • Bijlmakers MJE, Nakamura M, Ruddock LJ, Marsh M (1997). Intrinsic signals in the unique domain target p56lck to the plasma membrane independently of CD4. , 137, 1029 - 1040.
    • Riezman H, Woodman PG, Van Meer G, Marsh M (1997). Molecular mechanisms of endocytosis. Cell, 91(6), 731 - 738. doi:10.1016/S0092-8674(00)80461-4
    • Signoret N, Oldridge J, Pelchen-Matthews A, Klasse PJ, Tran T, Brass LF, Rosenkilde MM, Schwartz TW, Holmes W, Dallas W, Luther MA, Wells TNC, Hoxie JA, Marsh M (1997). Phorbol esters and SDF-1 induce rapid endocytosis and down modulation of the chemokine receptor CXCR4. , 139, 651 - 664.
    • Riezman H, Woodman PG, van Meer G, Marsh M (1997). Molecular mechanisms of endocytosis (Meeting report). , 91, 731 - 738.
    • Marsh M, Pelchen-Matthews A, Hoxie JA (1997). Roles for Endocytosis in Lentiviral Replication. , 7, 1 - 4.
    • Marsh M, Bron R (1997). SFV infection in CHO cells: Cell-type specific restrictions to productive virus entry at the cell surface.. , 110, 95 - 103.

    1996

    • Marsh M, Pelchen-Matthews A (1996). Endocytic And Exocytic Regulation Of CD4 Expression And Function.. , 205, 107 - 135.
    • Sauter MM, Pelchen-Matthews A, Bron R, Marsh M, LaBranche CC, Vance P, Romano J, Haggarty BS, Hart T, Lee WMF, Hoxie JA (1996). An internalization signal in the simian immunodeficiency virus transmembrane protein cytoplasmic domain modulates expression of envelope glycoproteins on the cell surface.. , 132, 795 - 812.
    • Wells TNC, Proudfoot AEI, Power CA, Marsh M (1996). Chemokine receptors - the new frontier for AIDS research. , 3, 603 - 609.
    • Marsh M, Helenius A, Matlin K, Simons K (1996). Binding, endocytosis and degradation of enveloped animal viruses.. In Packer LAF (Ed.), 'Biomembranes' Selected Methods in Enzymology (pp. 589 - 594). : Academic Press.
    • Endres MJ, Clapham PR, Marsh M, Ahuja M, Davis-Turner J, McKnight A, Thomas J, Stoebenau-Haggarty B, Choe S, Vance PJ, Wells TNC, Power CA, Sutterwala SS, Doms RW, Landau NR, Hoxie JA (1996). CD4-independent infection by HIV-2 is mediated by fusin. , 87, 745 - 756.

    1995

    • Pelchen-Matthews A, Clapham P, Marsh M (1995). Role of CD4 endocytosis in human immunodeficiency virus infection.. J Virol, 69(12), 8164 - 8168.
    • Pelchen-Matthews A, Clapham P, Marsh M (1995). The Role of CD4 Endocytosis in HIV Infection. , 69, 8164 - 8168.
    • LaBranche CC, Sauter MM, Haggarty BS, Vance PJ, Romano J, Hart TK, Bugelski PJ, Marsh M, Hoxie J (1995). A single amino acid change in the cytoplasmic domain of Simian Immunodeficiency Virus transmembrane molecule increases envelope glycoprotein expression on infected cells.. , 69, 5217 - 5227.
    • Frey S, Marsh M, Günther S, Pelchen-Matthews A, Stevens P, Ortlepp S, Stegmann T (1995). Temperature dependence of cell-cell fusion induced by the envelope glycoprotein of human immunodeficiency virus-1.. , 69, 1462 - 1472.

    1994

    • Marsh M, Pelchen-Matthews A (1994). The endocytic pathway and virus entry.. , , 215 - 240.
    • Ley S, Marsh M, Bebbington CR, Proudfoot K, Jordan P (1994). Distinct intracellular localization of Lck and Fyn protein tyrosine kinases in human T lymphocytes.. , 125, 639 - 649.
    • Marsh M (1994). Endocytosis. , First edition (Eds J.C. Kendrew et al.) Blackwell Science, Oxford, pp 321-322 - .

    1993

    • Marsh M (1993). Methods in Enzymology, Volume 219: Reconstitution of Intracellular transport, edited by James E. Rothman (Book review). , 18 (part 3), - .
    • Marsh M (1993). Biochemical and morphological assays of virus entry."Membrane fusion techniques" (Book review). , 220, 249 - 261.
    • Marsh M, Pelchen-Matthews A (1993). Entry of animal viruses into cells. Reviews in Medical Virology, 3(3), 173 - 185.
    • Paul NL, Marsh M, McKeating JA, Schulz TF, Liljeström P, Garoff H, Weiss RA (1993). Expression of HIV-1 envelope glycoproteins by Semliki Forest virus vectors.. AIDS Res Hum Retroviruses, 9(10), 963 - 970.
    • Marsh M, Pelchen-Matthews A (1993). Animal virus entry into cells.. , 3, 173 - 185.
    • Marsh M, Parsons IJ, Reid P, Pelchen-Matthews A (1993). Endocytic regulation in the T lymphocyte co-receptor proteins CD4 and CD8.. , 21, 703 - 706.
    • Marsh M (1993). Biochemical and morphological assays of virus entry.. Methods Enzymol, 220, 249 - 261.
    • Pelchen-Matthews A, Parsons IJ, Marsh M (1993). Phorbol ester-induced downregulation of CD4 is a multistep process involving dissociation from p56lck, increased association with clathrin-coated pits, and altered endosomal sorting.. J Exp Med, 178(4), 1209 - 1222.
    • Futter C, Marsh M (1993). Endocytosis and pasta.. Trends Cell Biol, 3(9), 316 - 318.
    • Futter C, Marsh M (1993). Endocytosis and pasta (Meeting report). , 3, 316 - 318.
    • Marsh M, Cutler D (1993). Taking the Rabs off endocytosis.. , 3, 30 - 32.
    • Marsh M, Cutler D (1993). Taking the Rabs off endocytosis.. Curr Biol, 3(1), 30 - 32.

    1992

    • Pelchen-Matthews A, Boulet I, Littman DR, Fagard R, Marsh M (1992). The protein tyrosine kinase p56lck inhibits CD4 endocytosis by preventing entry of CD4 into coated pits.. J Cell Biol, 117(2), 279 - 290.
    • Watts C, Marsh M (1992). Endocytosis: What goes in and how?. , 103, 1 - 8.
    • Marsh M (1992). Traffic jamming (Book review). , 2, 32 - .
    • Marsh M (1992). Keeping the viral coat on.. Curr Biol, 2(7), 379 - 381.
    • Marsh M, Reid P, Parsons I, Hermon C, Pelchen-Matthews A (1992). Morphological analysis of the regulation of CD4 endocytosis by p56lck.. Biochem Soc Trans, 20(4), 719 - 724.
    • Pelchen-Matthews A, Armes JE, Marsh M (1992). Endocytosis of CD4 in lymphoid and non-lymphoid cells.. , , 355 - 361.
    • Marsh M, Pelchen-Matthews A (1992). On the role of endocytosis in the entry of animal viruses.. , , 399 - 404.

    1991

    • Clements GJ, Price-Jones MJ, Stephens PE, Sutton C, Schulz TF, Clapham PR, McKeating JA, McClure MO, Thomson S, Marsh M, Kay J, Weiss RA, Moore JP (1991). The V3 loops of the HIV-1 and HIV-2 surface glycoproteins contain proteolytic cleavage sites: A possible function in viral fusion?. AIDS Research and Human Retroviruses, 7(1), 3 - 16.
    • Pelchen-Matthews A, Armes JE, Griffiths G, Marsh M (1991). Differential endocytosis of CD4 in lymphocytic and nonlymphocytic cells.. J Exp Med, 173(3), 575 - 587.
    • Marsh M (1991). Endosome and lysosome purification by free flow electrophoresis.. , , 199 - 213..

    1990

    • McClure MO, Sommerfelt MA, Marsh M, Weiss RA (1990). The pH independence of mammalian retrovirus infection.. J Gen Virol, 71 ( Pt 4), 767 - 773.
    • Marsh M, Armes JE, Pelchen-Matthews A (1990). Endocytosis and recycling of CD4.. Biochem Soc Trans, 18(2), 139 - 143.
    • Marsh M, Quinn P (1990). Membrane cycling through the exocytic and endocytic pathways.. , eds. Wilschut, J. and Hoekstra, D. Publ. Marcel Dekker Inc. New York., pp 421-448 - .

    1989

    • Marsh M (1989). Chapter 17 Endosome and Lysosome Purification by Free-Flow Electrophoresis. Methods in Cell Biology, 31(C), 319 - 334. doi:10.1016/S0091-679X(08)61617-9
    • Pelchen-Matthews A, Armes JE, Marsh M (1989). Internalization and recycling of CD4 transfected into HeLa and NIH3T3 cells.. EMBO J, 8(12), 3641 - 3649.
    • Weiss RA, Clapham PR, McClure M, Marsh M (1989). The CD4 receptor for the AIDS virus.. Biochem Soc Trans, 17(4), 644 - 647.
    • Willison K, Lewis V, Zuckerman KS, Cordell J, Dean C, Miller K, Lyon MF, Marsh M (1989). The t complex polypeptide 1 (TCP-1) is associated with the cytoplasmic aspect of Golgi membranes.. Cell, 57(4), 621 - 632.
    • Marsh M, Helenius A (1989). Virus entry into animal cells.. Adv Virus Res, 36, 107 - 151.
    • Marsh M (1989). Endosome and lysosome purification by free flow electrophoresis.. , 31, 319 - 334.
    • Griffiths G, Back R, Marsh M (1989). A quantitative analysis of the endocytic pathway in Baby Hamster Kidney cells.. , 109, 2703 - 2720.
    • Webster P, Marsh M (1989). Endocytosis by African Trypanosomes. , in "Protein Traffic in Parasites and Mammalian Cells: Proceedings of a Workshop held at the Internat, 156 - 160.

    1988

    • McClure MO, Marsh M, Weiss RA (1988). Human immunodeficiency virus infection of CD4-bearing cells occurs by a pH-independent mechanism.. EMBO J, 7(2), 513 - 518.
    • Marsh M (1988). The secretory and exocytic pathways (Book review). , 63, 335 - .
    • Marsh M, Kern H, Harms E, Schmid S, Mellman I, Helenius A (1988). Co-fractionation of BHK-21 cell endosomes and lysosomes by free-flow electrophoresis.. Prog Clin Biol Res, 270, 21 - 33.

    1987

    • Marsh M, Schmid S, Kern H, Harms E, Male P, Mellman I, Helenius A (1987). Rapid analytical and preparative isolation of functional endosomes by free flow electrophoresis. Journal of Cell Biology, 104(4), 875 - 886. doi:10.1083/jcb.104.4.875
    • Marsh M (1987). Enveloped virus entry.. , ed Rowland, D. et al. Publ. Academic Press Inc. London, pp281 - pp300.
    • Marsh M, Dalgleish A (1987). How does HIV enter cells?. , 8, 369 - 371.
    • Marsh M, Dalgleish A (1987). How do human immunodeficiency viruses enter cells?. Immunology Today, 8(12), 369 - 371. doi:10.1016/0167-5699(87)90211-8
    • Marsh M, Dalgleish A (1987). How do human immunodeficiency viruses enter cells?. Trends in Immunology, 8(12), 369 - 371.

    1986

    • Marsh M, Griffiths G, Dean GE, Mellman I, Helenius A (1986). Three-dimensional structure of endosomes in BHK-21 cells. Proceedings of the National Academy of Sciences of the United States of America, 83(9), 2899 - 2903.
    • Kielian MC, Marsh M, Helenius A (1986). Kinetics of endosome acidification detected by mutant and wild-type Semliki Forest virus.. , 5, 3103 - 3109.
    • Ukkonen P, Lewis V, Marsh M, Helenius A, Mellman I (1986). Transport of macrophage Fc receptors and Fc receptor-bound ligands to lysosomes.. , 163, 952 - 971.

    1985

    • Lewis V, Green S, Marsh M, Vikko P, Helenius A, Mellman I (1985). Glycoproteins of the lysosomal membrane.. , 100, 1839 - 1847.
    • Mellman I, Marsh M, Lewis V, Ukkonen P, Green S, Helenius A (1985). The control of membrane transport during endocytosis..

    1984

    • Marsh M, Keilian M, Helenius A (1984). Semliki Forest virus entry and the endocytic pathway.. , 12, 981 - 983.
    • Marsh M, Helenius A (1984). The endocytic pathway in BHK-21 cells as studied with Semliki Forest virus.. , 7 eds.Dingle, J.T., Dean, R.T. and Sly, W., pp297 - pp313.
    • Marsh M (1984). Entry of enveloped viruses into cells.. , 218, 1 - 10.

    1983

    • Marsh M, Helenius A, Matlin K, Simons K (1983). Binding, endocytosis and degradation of enveloped animal viruses.. , 98 eds. Fleischer, S. and Fleischer, R., pp260 - pp266.
    • Marsh M, Bolzau E, White J, Helenius A (1983). Interaction of subviral components with BHK-21 cells.. , 96, 455 - 461.
    • Marsh M, Bolzau E, Helenius A (1983). Semliki Forest virus penetration occurs from acid prelysosomal vacuoles.. , 32, 931 - 940.
    • Galloway C, Dean G, Marsh M, Rudnick G, Mellman I (1983). Acidification of macrophage and fibroblast endocytic vacuoles in vitro.. , 80, 3334 - 3338.

    1982

    • Marsh M, Wellsteed J, Kern H, Harms E, Helenius A (1982). Monensin inhibits Semliki Forest virus penetration into culture cells.. Proc Natl Acad Sci U S A, 79, 5297 - 5301.
    • Marsh M, Matlin K, Simons K, Reggio H, White J, Kartenbeck J, Helenius A (1982). Are lysosomes the site of enveloped virus penetration?. , 46, 835 - 843.
    • Helenius A, Marsh M, White J (1982). Effect of lysosomotropic weak bases on Semliki Forest virus penetration into host cells.. , 58, 47 - 61.
    • Helenius A, Marsh M (1982). Endocytosis of enveloped animal viruses.. , 92, pp59 - pp69.

    1981

    • Gardiner PR, Miller RH, Marsh M (1981). Studies on the rhizoplast from Naegleria gruberi.. , 47, 277 - 293.

    1980

    • Helenius A, Marsh M, White J (1980). Virus entry into animal cells.. , , - .
    • Marsh M, Helenius A (1980). Adsorptive endocytosis of Semliki Forest virus.. Journal of Molecular Biology, 142, 439 - 454.
    • Helenius A, Marsh M, White J (1980). The entry of viruses into animal cells.. , 5, 104 - 106.