Dr Mona Bajaj-Elliot

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Personal Profile

Name: Mona Bajaj-Elliot Email: m.bajaj-elliott@ucl.ac.uk
Title: Dr Tel:
Department: ICH Infect, Imm, Infla. & Physio Med Fax:
Position: Senior Lecturer Address: , , ,
Research Domain: Infection, Immunology & Inflammation, Personalised Medicine, Populations & Lifelong Health Web Page:  

Profile

Research Description

Maintaining homeostasis at mucosal surfaces is a complex affair. These interfaces have to provide protection and tolerance at the same time. With an epithelial lining that is only a single cell thick (unlike the hardy skin) protecting the underlying mucosa, the Gastrointestinal (GI) tract faces unique challenges. It has to co-exist with trillions of bacteria (unlike the sterile lung) called commensals (good bacteria) and yet provide protection against opportunistic enteropathogens (Enteropathogenic E. coli, Clostridium difficile, Salmonella and Campylobacter species). In addition to dealing with the microbial world, the GI mucosal immune system is central to aiding tolerance to food antigens. If not, immune-mediated (e.g. Celiac disease, Food allergy) or non-immune mediated inflammation may ensue.

The central hypothesis of our research is that GI health is maintained via appropriate cross-talk between the GI mucosal immune system (host genetics) and its luminal contents (microbiota/pathogens/food antigens). Our laboratory is focused on identifying both exogenous (microbial/food allergens) and host components that are involved in this interplay.  A better understanding of these multifaceted interactions holds the key for unlocking cellular events responsible for a variety of GI inflammatory conditions. 

Current areas of research include:

(a) Understanding Clostridium difficile-mediated antibiotic associated diarrhoea and related complications, which currently represent a significant health burden in the developed world.

(b) Understanding Campylobacter jejuni (a commensal of chicken gut)-mediated disease pathogenesis. Currently, this bacterium is the major cause of bacterial gastroenteritis worldwide.

(c) How do enteropathogens manipulate major host cellular processes (in particular the inflammasome and the autophagy machinery) leading to successful immune evasion.

(d) Inflammatory Bowel Disease (Crohn’s Disease and Ulcerative Colitis) disease pathogenesis

(e) Identify potential biomarkers for gut allergic diseases.


Research Activities

Immunopathogenesis of paediatric autoimmune diseas

pediatric sepsis

Education Description

Teaching responsibilities include:

MRes in Biomedicine: Director (since 2007). MRes (MSc by Research) in Biomedicine is a 1 year course that has been running successfully since 2001. The course is unique amongst postgraduate courses as it offers students an opportunity to conduct two (instead of one) laboratory-based projects, thus arming them with greater polished skills for entering a higher degree and/or the job market. A great majority of students successfully enter PhD programmes in the UK and in Europe.

MRes in Biomedicine: Module Director (Foundations of Biomedical Sciences)

MSc in Infection and Immunity: Module co-director (Infection and Immunodeficiency in Children)

iBSc Paediatrics and Child Health: Module director (Laboratory methods in Biomedical Sciences)

UCL Collaborators

Prof Adrian Thrasher; Dr Mike Hubank; Prof Nigel Klein; Prof Donald Peebles; Prof Robin Callard; Dr Paul Brogan; Prof Deenan Pillay; Prof Lucy Wedderburn

External Collaborators

Publications

    2014

    • Stephenson HN, Mills DC, Jones H, Milioris E, Copland A, Dorrell N, Wren BW, Crocker PR, Escors D, Bajaj-Elliott M (2014). Pseudaminic Acid on Campylobacter jejuni Flagella Modulates Dendritic Cell IL-10 Expression via Siglec-10 Receptor: a Novel Flagellin-Host Interaction.. J Infect Dis, , - . doi:10.1093/infdis/jiu287
    • Jafari NV, Songane M, Stabler RA, Elawad M, Wren BW, Allan E, Bajaj-Elliott M (2014). Host immunity to Clostridium difficile PCR ribotype 017 strains.. Infect Immun, , - . doi:10.1128/IAI.02605-14
    • James CP, Bajaj-Elliott M, Syngelaki A, Klein N, Nicolaides K, Peebles DM (2014). Systemic Innate Immune Response in the First Trimester Is Related to DEFB1 Genotype, and Is Distinct in Women Who Develop PPROM and Deliver before 34 Weeks of Gestation. REPRODUCTIVE SCIENCES, 21(3), 239A - 239A.
    • James C, Bajaj-Elliott M, Syngelaki A, Klein N, Nicolaides K, Peebles D (2014). Systemic innate immune response in the first trimester is related to DEFB1 genotype, and is distinct in women who develop PPROM and deliver before 34 weeks of gestation. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 121(7), E11 - E11.
    • James C, Bajaj-Elliott M, Syngelaki A, Klein N, Nicolaides K, Peebles D (2014). 8.4 Serum beta defensin concentration in the first trimester is related to genotype, and is higher in women who develop PPROM and deliver before 34 weeks.. Arch Dis Child Fetal Neonatal Ed, 99 Suppl 1, A12 - . doi:10.1136/archdischild-2014-306576.33

    2013

    • Dommett R, Chisholm J, Turner M, Bajaj-Elliott M, Klein NJ (2013). Mannose-binding lectin genotype influences frequency and duration of infectious complications in children with malignancy.. J Pediatr Hematol Oncol, 35(1), 69 - 75. doi:10.1097/MPH.0b013e31827076e5
    • Songane MJ, Kuehne S, Hussain H, Klein N, Minton N, Allan E, Bajaj-Elliott M (2013). Mechanism(s) involved in Clostridium difficile-mediated Inflammasome activation.
    • James CP, Klein N, Bajaj-Elliott M, Peebles D (2013). Progesterone Modulates Cervical Antimicrobial Immunity..
    • Stephenson HN, John CM, Naz N, Gundogdu O, Dorrell N, Wren BW, Jarvis GA, Bajaj-Elliott M (2013). Campylobacter jejuni lipooligosaccharide sialylation, phosphorylation, and amide/ester linkage modifications fine-tune human Toll-like receptor 4 activation.. J Biol Chem, 288(27), 19661 - 19672. doi:10.1074/jbc.M113.468298
    • Jafari NV, Kuehne SA, Bryant CE, Elawad M, Wren BW, Minton NP, Allan E, Bajaj-Elliott M (2013). Clostridium difficile Modulates Host Innate Immunity via Toxin-Independent and Dependent Mechanism(s).. PLoS One, 8(7), e69846 - . doi:10.1371/journal.pone.0069846
    • James CP, Bajaj-Elliott M, Syngelaki A, Klein N, Nicolaides K, Peebles D (2013). Variation in Beta Defensin 1 Genotype Is Associated with Preterm Birth..
    • James C, Bajaj-Elliott M, Syngelaki A, Klein N, Nicolaides K, Peebles D (2013). Association of human beta defensin-1 (DEFB1) polymorphisms and in vivo protein expression: first population-based analysis.

    2012

    • Pramanik N, Lucas M, Klein N, Bryant C, Bajaj-Elliott M (2012). Enteropathogenic Escherichia coli engages in temporal regulation of the inflammasome by interaction with NLRC4 and NALP3.
    • Elmi A, Watson E, Sandu P, Gundogdu O, Mills DC, Inglis NF, Manson E, Imrie L, Bajaj-Elliott M, Wren BW, Smith DG, Dorrell N (2012). Campylobacter jejuni outer membrane vesicles play an important role in bacterial interactions with human intestinal epithelial cells.. Infect Immun, 80(12), 4089 - 4098. doi:10.1128/IAI.00161-12
    • Milioris E, Iebba V, Klein NJ, Steevels T, Simmons A, Bajaj-Elliott M (2012). The impact of NOD2 3020insC mutation in microbial-driven host innate immunity.
    • Mills DC, Gundogdu O, Elmi A, Bajaj-Elliott M, Taylor PW, Wren BW, Dorrell N (2012). Increase in Campylobacter jejuni invasion of intestinal epithelial cells under low-oxygen coculture conditions that reflect the in vivo environment.. Infect Immun, 80(5), 1690 - 1698. doi:10.1128/IAI.06176-11

    2011

    • Nistala K, Adams S, Cambrook H, Ursu S, Olivito B, de Jager W, Evans JG, Cimaz R, Bajaj-Elliott M, Wedderburn LR (2011). Th17 cells that undergo plasticity to a Th1 phenotype in human autoimmune arthritis can be detected by the expression of CD161 within the inflamed joint. CLIN EXP RHEUMATOL, 29(2), 449 - 449.
    • Edwards LA, Lucas M, Edwards EA, Torrente F, Heuschkel RB, Klein NJ, Murch SH, Bajaj-Elliott M, Phillips AD (2011). Aberrant response to commensal Bacteroides thetaiotaomicron in Crohn's disease: an ex vivo human organ culture study.. Inflamm Bowel Dis, 17(5), 1201 - 1208. doi:10.1002/ibd.21501
    • Edwards LA, Bajaj-Elliott M, Klein NJ, Murch SH, Phillips AD (2011). Bacterial-epithelial contact is a key determinant of host innate immune responses to enteropathogenic and enteroaggregative Escherichia coli.. PLoS One, 6(10), e27030 - . doi:10.1371/journal.pone.0027030

    2010

    • Jafari NV, Allan E, Bajaj-Elliott M (2010). Human intestinal epithelial response(s) to Clostridium difficile.. Methods Mol Biol, 646, 135 - 146. doi:10.1007/978-1-60327-365-7_9
    • Shah N, Cambrook H, Koglmeirer J, Mason C, Ancliff P, Lindley K, Smith VV, Bajaj-Elliott M, Sebire NJ (2010). Enteropathic histopathological features may be associated with Shwachman-Diamond syndrome. Journal of Clinical Pathology, 63(7), 592 - 594.
    • Edwards LA, Lucas M, Edwards EA, Torrente F, Heuschkel RB, Klein NJ, Murch SH, Bajaj-Elliott M, Phillips AD (2010). Aberrant response to commensal Bacteroides thetaiotaomicron in Crohn's disease: An ex vivo human organ culture study.. Inflamm Bowel Dis, , - . doi:10.1002/ibd.21501
    • Shah N, Cambrook H, Koglmeier J, Mason C, Ancliff P, Lindley K, Smith VV, Bajaj-Elliott M, Sebire NJ (2010). Enteropathic histopathological features may be associated with Shwachman-Diamond syndrome.. J Clin Pathol, 63(7), 592 - 594. doi:10.1136/jcp.2010.077677
    • Nistala K, Adams S, Cambrook H, Ursu S, Olivito B, de Jager W, Evans JG, Cimaz R, Bajaj-Elliott M, Wedderburn LR (2010). Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment.. Proc Natl Acad Sci U S A, 107(33), 14751 - 14756. doi:10.1073/pnas.1003852107
    • Kazakos EI, Alhaj-Hussein B, Bajaj-Elliott M, Dorrell N (2010). In vitro effects of human beta-defensins on planktonic cells, bacterial adhesion and biofilm formation of the two sequenced strains of H-pylori.
    • Edwards LA, Nistala K, Mills DC, Stephenson HN, Zilbauer M, Wren BW, Dorrell N, Lindley KJ, Wedderburn LR, Bajaj-Elliott M (2010). Delineation of the innate and adaptive T-cell immune outcome in the human host in response to Campylobacter jejuni infection.. PLoS One, 5(11), e15398 - . doi:10.1371/journal.pone.0015398

    2009

    • Dhaliwal W, Kelly P, Bajaj-Elliott M (2009). Differential effects of Staphylococcal enterotoxin B-mediated immune activation on intestinal defensins. Clinical and Experimental Immunology, 156(2), 263 - 270.
    • Zilbauer M, Dorrell N, Nunez G, Klein NJ, Wren BW, Wirth S, Bajaj-Elliott M (2009). The role of NOD1 as major pattern recognition receptor for detection of Campylobacter jejuni by the intestinal epithelia. EUR J PEDIATR, 168(3), 378 - 378.
    • Choudhry N, Korbel DS, Zaalouk TK, Blanshard C, Bajaj-Elliott M, McDonald V (2009). Interferon-gamma-mediated activation of enterocytes in immunological control of Encephalitozoon intestinalis infection.. Parasite Immunol, 31(1), 2 - 9. doi:10.1111/j.1365-3024.2008.01068.x
    • Choudhry N, Korbel DS, Edwards LA, Bajaj-Elliott M, McDonald V (2009). Dysregulation of interferon-gamma-mediated signalling pathway in intestinal epithelial cells by Cryptosporidium parvum infection. Cellular Microbiology, 11(9), 1354 - 1364. doi:10.1111/j.1462-5822.2009.01336.x
    • Edwards LA, Nistala K, Mills DC, Dorrell N, Lindley KJ, Wedderburn L, Bajaj-Elliott M (2009). Campylobacter Jejuni-Mediated Effects On Dendritic Cell IL-12/IL-23 Axis: Impact On T Cell Mediated Immunity.

    2008

    • Zilbauer M, Dorrell N, Wren BW, Bajaj-Elliott M (2008). Campylobacter jejuni-mediated disease pathogenesis: an update. Transactions of the Royal Society of Tropical Medicine and Hygiene, 102(2), 123 - 129.
    • Choudhry N, Bajaj-Elliott M, McDonald V (2008). Terminal Sialic Acid of Glycoconjugates on the Surface of Intestinal Epithelial Cells Activates Excystation of Cryptosporidium parvum. Infection and Immunity, 76(8), 3735 - 3741.
    • Dzwonek AB, Neth OW, Thiebaut R, Gulczynska E, Chilton M, Hellwig T, Bajaj-Elliott M, Hawdon J, Klein NJ (2008). The role of mannose-binding lectin in susceptibility to infection in preterm neonates. Pediatr Res, 63(6), 680 - 685.

    2007

    • Zilbauer M, Dorrell N, Elmi A, Nunez G, Klein NJ, Wren BW, Bajaj-Elliott M (2007). A major role for intestinal epithelial nucleotide oligomerization domain (NOD) protein NOD1 in mediating host bactericidal activity against Campylobacter jejuni. ZOONOSES PUBLIC HLTH, 54, 148 - 148.
    • Elmi AD, Zilbauer M, Bajaj-Elliott M, Wren B, Dorrell N (2007). Investigation of the role of two Campylobacter jejuni glycoproteins during bacterial interactions with human intestinal epithelial cells. ZOONOSES PUBLIC HLTH, 54, 99 - 99.
    • Zilbauer M, Dorrell N, Elmi A, Lindley KJ, Schuller S, Jones HE, Klein NJ, Nunez G, Wren BW, Bajaj-Elliott M (2007). A major role for intestinal epithelial nucleotide oligomerization domain 1 (NOD1) in eliciting host bactericidal immune responses to Campylobacter jejuni (vol 9, pg 2404, 2007). CELL MICROBIOL, 9(10), 2541 - 2541. doi:10.1111/j.1462-5822.2007.01008.x
    • Kazakos E, Bisiklis A, Alexiou-Daniel S, Bajaj-Elliott M (2007). Activity of human beta-defensin 3 against metallo-beta-lactamase-producing Pseudomonas aeruginosa strains.
    • Zilbauer M, Dorrell N, Elmi A, Lindley KJ, Schuller S, Jones HE, Klein NJ, Nunez G, Wren BW, Bajaj-Elliott M (2007). A major role for intestinal epithelial nucleotide oligomerization domain 1 (NOD1) in eliciting host bactericidal immune responses to Campylobacter jejuni.. Cellular Microbiology, 9(10), 2404 - 2416. doi:10.1111/j.1462-5822.2007.00969.x
    • Zilbauer M, Dorrell N, Elmi A, Lindley K, Klein N, Nunez G, Wren B, Bajaj-Elliott M (2007). A major role for intestinal epithelial nucleotide oligomerization domain 1 (NOD1) in mediating host bactericidal activity against Campylobacter jejuni. J PEDIATR GASTR NUTR, 44, 116 - 116.
    • Edwards LA, Murch S, Klein N, Bajaj-Elliott M, Phillips AD (2007). Probiotic and commensal bacteria differentially regulate intestinal epithelial cell innate defence gene expression. J PEDIATR GASTR NUTR, 44, 138 - 138.
    • Edwards L, Murch S, Heuschkel R, Torrente F, Klein N, Bajaj-Elliott M, Phillips AD (2007). Human intestinal in vitro organ culture response to bacterial exposure in Crohn's disease. J PEDIATR GASTR NUTR, 44, 23 - 23.

    2006

    • Hatzifoti C, Roussel Y, Harris AG, Wren BW, Morrow JW, Bajaj-Elliott M (2006). Mucosal immunization with a urease B DNA vaccine induces innate and cellular immune responses against Helicobacter pylori. Helicobacter, 11(2), 113 - 122.
    • McDonald V, Pollok RC, Dhaliwal W, Naik S, Farthing MJ, Bajaj-Elliott M (2006). A potential role for interleukin-18 in inhibition of the development of Cryptosporidium parvum. Clinical and Experimental Immunology, 145(3), 555 - 562.
    • Boughan PK, Argent RH, Body-Malapel M, Park JH, Ewings KE, Bowie AG, Ong SJ, Cook SJ, Sorensen OE, Manzo BA, Klein NJ, Nunez G, Atherton JC, Bajaj-Elliott M (2006). Nucleotide-binding oligomerisation domain-1 (NOD-1) and epidermal growth factor receptor (EGFR): Critical regulators of beta -defensins during helicobacter pylori infection. Journal of Biological Chemistry, 281(17), 11637 - 11648. doi:10.1074/jbc.M510275200
    • Dzwonek A, Novelli V, Bajaj-Elliott M, Turner M, Clapson M, Klein N (2006). Mannose-binding lectin in susceptibility and progression of HIV-1 infection in children. Antiviral Therapy, 11(4), 499 - 505.
    • Kelly P, Bajaj-Elliott M, Katubulushi M, Zulu I, Poulsom R, Feldman RA, Bevins CL, Dhaliwal W (2006). Reduced gene expression of intestinal alpha-defensins predicts diarrhea in a cohort of African adults. The Journal of Infectious Diseases, 193(10), 1464 - 1470.
    • Dommett RM, Bajaj-Elliott M, Chisholm J, Klein N (2006). Influence of mannose binding lectin (MBL) gene polymorphisms on infectious complications during treatment for childhood malignancy..
    • Manzo BA, Crabtree JE, Fiona Campbell M, Tweedle D, Potten CS, Bajaj-Elliott M, Sanderson IR, Wilson JW (2006). Helicobacter pylori regulates the expression of inhibitors of DNA binding (Id) proteins by gastric epithelial cells. Microbes Infect, 8(4), 1064 - 1074.

    2005

    • Kazakos EI, Harris A, Ong SJ, Boughan PK, Curtis M, Bajaj-Elliott M (2005). Host innate immune response to Helicobacter pylori infection. Helicobacter, 10(5), 496 - 496.
    • Bajaj-Elliott M, Turner M (2005). Innate immunity in health and disease. MOL IMMUNOL, 42(8), 857 - 858.
    • Boughan PK, Argent RH, Bowie AG, Ong SJ, Cook SJ, Sorensen O, Klein NJ, Atherton JC, Bajaj-Elliott M (2005). Modulation of gastric epithelial human beta-defensins (HBD)-2 and -3 during Helicobacter pylori infection. Helicobacter, 10(5), 494 - 494.
    • Dommett R, Zilbauer M, George JT, Bajaj-Elliott M (2005). Innate immune defence in the human gastrointestinal tract. Molecular Immunology, 42(8), 903 - 912.
    • Neth OW, Bajaj-Elliott M, Turner MW, Klein NJ (2005). Susceptibility to infection in patients with neutropenia: the role of the innate immune system. British Journal of Haematology, 129(6), 713 - 722.
    • Zilbauer M, Dorrell N, Boughan PK, Harris A, Wren BW, Klein NJ, Bajaj-Elliott M (2005). Intestinal innate immunity to Campylobacter jejuni results in induction of bactericidal human beta-defensins 2 and 3. Infection and Immunity, 73(11), 7281 - 7289. doi:10.1128/IAI.73.11.7281-7289.2005

    2004

    • McDonald SA, O'Grady JE, Bajaj-Elliott M, Notley CA, Alexander J, Brombacher F, McDonald V (2004). Protection against the early acute phase of Cryptosporidium parvum infection conferred by interleukin-4-induced expression of T helper 1 cytokines.. J Infect Dis, 190(5), 1019 - 1025. doi:10.1086/422761
    • Hatzifoti C, Bajaj-Elliott M, Dorrell N, Anyim M, Prentice MB, Nye KE, Wren B, Morrow WJ (2004). A plasmid immunization construct encoding urease B of Helicobacter pylori induces an antigen-specific antibody response and upregulates the expression of beta-defensins and IL-10 in the stomachs of immunized mice.. Vaccine, 22(20), 2651 - 2659. doi:10.1016/j.vaccine.2003.11.056
    • Zilbauer M, Dorrell N, Wren BW, Klein NJ, Bajaj-Elliott M (2004). Host innate defence to Campylobacter jejuni.
    • Zaalouk TK, Bajaj-Elliott M, George JT, McDonald V (2004). Antimicrobial activity of beta defensins against Cryptosporidium parvum.
    • Boughan PK, George JT, Argent R, Atherton J, Bajaj-Elliott M (2004). Regulation of host innate immune responses during H-pylori infection.
    • Zilbauer M, Dorrell N, George J, Boughan P, Bajaj-Elliott M (2004). The role of human beta-defensins during Campylobacter jejuni infection.
    • Zaalouk TK, Bajaj-Elliott M, George JT, McDonald V (2004). Differential regulation of beta-defensin gene expression during Cryptosporidium parvum infection.. Infect Immun, 72(5), 2772 - 2779.

    2003

    • Bajaj-Elliott M (2003). Trypsin and host defence: a new role for an old enzyme.. Gut, 52(2), 166 - 167.
    • Manzo BA, Bajaj-Elliott M, Atherton JC, Thomas RJ, Sanderson IR, Wilson JW (2003). Helicobacter pylori regulates expression of ID-1 and ID-3 but not ID-2.
    • McDonald SAC, Bajaj-Elliott M, Smith PT, Ballinger AB, McDonald V (2003). Immunity to Cryptosporidium parvum: A role for IL-4 in the early adaptive immune response.
    • George JT, Boughan PK, Karageorgiou H, Bajaj-Elliott M (2003). Host anti-microbial response to Helicobacter pylori infection. Molecular Immunology, 40(7), 451 - 456.
    • Lean IS, McDonald SA, Bajaj-Elliott M, Pollok RC, Farthing MJ, McDonald V (2003). Interleukin-4 and transforming growth factor beta have opposing regulatory effects on gamma interferon-mediated inhibition of Cryptosporidium parvum reproduction.. Infect Immun, 71(8), 4580 - 4585.
    • Smith GV, Moran AP, Bajaj-Elliott M, Farthing MJ (2003). Induction of cyclooxygenase 2 by Escherichia coli but not Helicobacter pylori lipopolysaccharide in gastric epithelial cells in vitro.. Helicobacter, 8(5), 513 - 520.
    • Dhaliwal W, Bajaj-Elliott M, Kelly P (2003). Intestinal defensin gene expression in human populations.. Mol Immunol, 40(7), 469 - 475.
    • Dhaliwal W, Bajaj-Elliott M, Kelly P (2003). Role of T cells in the regulation of human intestinal alpha defensin gene expression.
    • Manzo BA, Bajaj-Elliott M, Atherton J, Thomas R, Sanderson IR, Wilson JW (2003). Helicobacter pylori regulates Id-1 and Id-3 expression, but not Id-2.

    2002

    • Bajaj-Elliott M, Fedeli P, O'Neil D (2002). Interferon-gamma blocks the interleukin-1 and bacterially mediated induction of human beta-defensin 2 expression in gastric and intestinal epithelial cells. GUT, 50, A69 - A69.
    • Notley CA, McDonald SA, Bajaj-Elliott M, O'Grady J, Alexander J, Brombacher F, McDonald V (2002). The requirement for IL-4 in immunological control of murine Cryptosporidium parvum infection varies with mouse strain. GASTROENTEROLOGY, 122(4), A144 - A144.
    • Pollok RCG, McDonald V, Farthing MJG, Bajaj-Elliott M (2002). Functional IL-18 receptor expression by human intestinal epithelial cells required for inhibition of Cryptosporidium parvum development by IL-18. GUT, 50, A28 - A28.
    • Fitzgerald RC, Onwuegbusi BA, Bajaj-Elliott M, Saeed IT, Burnham WR, Farthing MJ (2002). Diversity in the oesophageal phenotypic response to gastro-oesophageal reflux: immunological determinants. GUT, 50(4), 451 - 459.
    • Dhaliwal W, Bajaj-Elliott M, Poulsom R, Ghosh D, Bevins C, Kelly P (2002). Increased expression of alpha-defensins with increasing severity of tropical enteropathy. GASTROENTEROLOGY, 122(4), A150 - A150.
    • Dhaliwal W, Bajaj-Elliott M, Poulsom R, Ghosh D, Bevins C, Kelly P (2002). Increased expression of alpha-defensins with increasing severity of tropical enteropathy. GUT, 50, A68 - A68.
    • Salvati VM, MacDonald TT, Bajaj-Elliott M, Borrelli M, Staiano A, Auricchio S, Troncone R, Monteleone G (2002). Interleukin 18 and associated markers of T helper cell type 1 activity in coeliac disease. GUT, 50(2), 186 - 190.
    • Simmons CP, Goncalves NS, Ghaem-Maghami M, Bajaj-Elliott M, Clare S, Neves B, Frankel G, Dougan G, MacDonald TT (2002). Impaired resistance and enhanced pathology during infection with a noninvasive, attaching-effacing enteric bacterial pathogen, Citrobacter rodentium, in mice lacking IL-12 or IFN-gamma. J IMMUNOL, 168(4), 1804 - 1812.
    • Bajaj-Elliott M, Fedeli P, Smith GV, Domizio P, Maher L, Ali RS, Quinn AG, Farthing MJ (2002). Modulation of host antimicrobial peptide (beta-defensins 1 and 2) expression during gastritis. Gut, 51(3), 356 - 361. doi:10.1136/gut.51.3.356

    2001

    • Pollok RCG, McDonald V, Bajaj-Elliott M, Farthing MJG (2001). MAP kinase inhibition reverses Cryptosporidium parvum induced IL-8 secretion by enterocytes. GUT, 48, A74 - A74.
    • Pollok RCG, McDonald V, Farthing MJG, Bajaj-Elliott M (2001). Increased expression of pro-IL-18 by intestinal epithelial cells infected with Cryptosporidium parvum. GUT, 48, A18 - A18.
    • Salvati VM, Bajaj-Elliott M, Poulsom R, Mazzarella G, Lundin KE, Nilsen EM, Troncone R, MacDonald TT (2001). Keratinocyte growth factor and coeliac disease. GUT, 49(2), 176 - 181.
    • Dhaliwal W, Bajaj-Elliott M, Sianongo S, Munkanta M, Shen B, Ghosh D, Feakins R, Farthing MJ, Bevins CL, Kelly P (2001). Alpha-defensin expression in human jejunum varies in HIV infection and tropical enteropathy. GASTROENTEROLOGY, 120(5), A152 - A152.
    • Dhaliwal W, Bajaj-Elliott M, Sianongo S, Munkanta M, Shen B, Ghosh D, Feakins R, Farthing MJG, Bevins CL, Kelly P (2001). Alpha-defensin expression in human jejunum varies in HIV infection and tropical enteropathy. GUT, 48, A74 - A74.
    • Kaskas BA, Salvati VM, Troncone R, Bajaj-Elliott M, MacDonald TT (2001). Epithelial growth factors in coeliac disease. GASTROENTEROLOGY, 120(5), A395 - A395.
    • Ballinger AB, Azooz OG, Bajaj-Elliott M, Farthing M (2001). The reduction in insulin-like growth factor-1 and linear growth in a rat model of colitis is mediated by the combined inhibitory effects of interleukin-6 and undernutrition. GASTROENTEROLOGY, 120(5), A210 - A210.
    • Goncalves N, Simmons CP, Ghaem-Maghami M, Monteleone G, Bajaj-Elliott M, Goldin R, Frankel G, Dougan G, MacDonald TT (2001). The role of IL-12 and IFN-gamma in immunity to Citrobacter rodentium infection. GUT, 48, A75 - A75.
    • Fedeli P, Farthing MJG, Smith GV, Bajaj-Elliott M (2001). Increased expression of human beta-defensins (hBD) 1 and 2 in H-pylori-positive and -negative gastritis. GUT, 48, A72 - A72.
    • Pollok RC, Farthing MJ, Bajaj-Elliott M, Sanderson IR, McDonald V (2001). Interferon gamma induces enterocyte resistance against infection by the intracellular pathogen Cryptosporidium parvum. Gastroenterology, 120(1), 99 - 107. doi:10.1053/gast.2001.20907

    2000

    • Bajaj-Elliott M, Maher L, Zhang ZW, Farthing MJ (2000). Induction of human B2 defensin (hBD2) mRNA expression by H.pylori in human gastric epithelial cell lines.. GASTROENTEROLOGY, 118(4), A1213 - A1213.
    • Pollok RC, Farthing MJ, Bajaj-Elliott M, McDonald V (2000). Cellular mechanisms of interferon-Gamma mediated inhibition of Cryptosporidium parvum infection.. GASTROENTEROLOGY, 118(4), A817 - A817.
    • Maher LS, Bajaj-Elliott M, Farthing MG (2000). Effect of Helicobacter pylori on the expression of the E-cadherin-catenin complex in gastric epithelial cells.. GASTROENTEROLOGY, 118(4), A760 - A761.
    • Onwuegbusi BA, Fitzgerald RC, Bajaj-Elliott M, Burnham WR, Farthing MJ (2000). Distinct cytokine patterns in Barrett's oesophagus and associated adenocarcinoma: Evidence for a shift tewards a Th-2 response.. GASTROENTEROLOGY, 118(4), A37 - A37.
    • Heuschkel RB, MacDonald TT, Monteleone G, Bajaj-Elliott M, Smith JA, Pender SL (2000). Imbalance of stromelysin-1 and TIMP-1 in the mucosal lesions of children with inflammatory bowel disease.. Gut, 47(1), 57 - 62.
    • Nagata S, McKenzie C, Pender SL, Bajaj-Elliott M, Fairclough PD, Walker-Smith JA, Monteleone G, MacDonald TT (2000). Human Peyer's patch T cells are sensitized to dietary antigen and display a Th cell type 1 cytokine profile.. J Immunol, 165(9), 5315 - 5321.
    • Egger B, Bajaj-Elliott M, MacDonald TT, Inglin R, Eysselein VE, Büchler MW (2000). Characterisation of acute murine dextran sodium sulphate colitis: cytokine profile and dose dependency.. Digestion, 62(4), 240 - 248.

    1999

    • Bajaj-Elliott M, Pender S, MacDonald TT (1999). Functional role of keratinocyte growth factor (KGF) and transforming growth factor-alpha (TGF-alpha) in mediating T-cell-induced crypt cell hyperplasia in the gut.
    • MacDonald TT, Bajaj-Elliott M, Pender SL (1999). T cells orchestrate intestinal mucosal shape and integrity.. Immunol Today, 20(11), 505 - 510.
    • Heuschkel RB, Pender SLF, Bajaj-Elliott M, Smith JAW, MacDonald TT (1999). Imbalance of stromelysin-1 and TIMP-1 mRNA and protein in the mucosal lesions of children with inflammatory bowel disease. GASTROENTEROLOGY, 116(4), A736 - A736.
    • Egger B, Bajaj-Elliott M, MacDonald TT, Farhadi J, Eysselein VE, Buchler MW (1999). The tissue cytokine profile in acute dextran sulfate (DSS) induced mucosal injury in mice is similar td that observed in Crohn's disease. GASTROENTEROLOGY, 116(4), A705 - A705.

    1998

    • Bajaj-Elliott M, Pender SL, Poulsom R, Macdonald TT (1998). Upregulation of keratinocyte growth factor during T-cell immunity in the gut mucosa.. Ann N Y Acad Sci, 859, 184 - 187.
    • Bajaj-Elliott M, Poulsom R, Pender SL, Wathen NC, MacDonald TT (1998). Interactions between stromal cell--derived keratinocyte growth factor and epithelial transforming growth factor in immune-mediated crypt cell hyperplasia.. J Clin Invest, 102(8), 1473 - 1480. doi:10.1172/JCI2792
    • Hauer AC, Bajaj-Elliott M, Williams CB, Walker-Smith JA, MacDonald TT (1998). An analysis of interferon gamma, IL-4, IL-5 and IL-10 production by ELISPOT and quantitative reverse transcriptase-PCR in human Peyer's patches.. Cytokine, 10(8), 627 - 634. doi:10.1006/cyto.1997.0337

    1997

    • Bajaj-Elliott M, Breese E, Poulsom R, Fairclough PD, MacDonald TT (1997). Keratinocyte growth factor in inflammatory bowel disease. Increased mRNA transcripts in ulcerative colitis compared with Crohn's disease in biopsies and isolated mucosal myofibroblasts.. Am J Pathol, 151(5), 1469 - 1476.