Dr Jonathan Schott

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Personal Profile

Name: Jonathan Schott Email: j.schott@ucl.ac.uk
Title: Dr Tel: 020 3448 3553
Department: Neurodegenerative Diseases Fax:
Position: Senior Clinical Lecturer Address: Institute of Neurology, 8-11 Queen Square, London, WC1N 3BG
Research Domain: Ageing, Biomedical Imaging (Frontier Disciplines), Neuroscience Web Page:  

Profile

Research Description

My research interests are centred on translational research in the dementias, including: the development and application of imaging and cerebrospinal fluid biomarkers in the degenerative dementias for early, specific diagnosis and disease tracking; atypical and young onset dementia; genotype/phenotype correlations in neurodegeneration; clinical trials; autoimmune dementia syndromes; and normal and abnormal ageing. I have several national and international collaborations, including heading an international consortium to determine the genetics of posterior cortical atrophy. I currently supervise 5 PhD students. I have published >75 Medline referenced papers in journals including the Lancet, Lancet Neurology, Annals of Neurology, Archives of Neurology, Brain, and Neurology, and have reviewed papers and grants for numerous journals and grant giving bodies, including the MRC and US NIH. I have authored editorials for journals including Neurology and the BMJ. I have been appointed co-editor (with Prof Masud Husain) of the Oxford Textbook of Cognition and Dementia. I have spoken at numerous national and international conferences, including meetings of the US Alzheimer's Association, European Federation of Neurosciences, Association of British Neurologists and American Academy of Neurology. I am an invited member of the European Federation on Neurological Sciences Dementia Panel, where the focus is on producing evidenced based practice guidelines.


Research Activities

Education Description

 I am involved in teaching at local (undergraduate, MSc, postgraduate), national (including BMJ Neurology Masterclass) and international (including European Federation of Neurological Sciences). I am a member of the Royal College of Physicians Neurology Speciality Certificate Examination standard setting committee.

UCL Collaborators

External Collaborators

Publications

    2014

    • Ahmed RM, Schott JM, Mummery CJ, Rohrer JD, Fox NC, Murphy E, Lachmann RH, Davagnanam I, Parton M, Houlden H, Chataway J (2014). A practical approach to diagnosing adult onset leukodystrophies. Journal of Neurology, Neurosurgery and Psychiatry, 85(7), 770 - 781. doi:10.1136/jnnp-2013-305888
    • Slattery C, Beck J, Harper L, Adamson G, Abdi Z, Uphill J, Campbell T, Druyeh R, Mahoney C, Rohrer J, Kenny J, Lowe J, Leung K, Barnes J, Clegg S, Blair M, Nicholas J, Guerreiro R, Rowe J, Ponto C, Zerr I, Kretzschmar H, Gambetti P, Crutch S, Warren J, Rossor M, Fox N, Collinge J, Schott J, Mead S (2014). Trem2 variants increase risk of typical early-onset Alzheimer's disease but not of prion or frontotemporal dementia.. J Neurol Neurosurg Psychiatry, 85(8), e3 - . doi:10.1136/jnnp-2014-308883.7
    • Paterson RW, Schott JM, Zandi MS, Armstrong R, Vincent A (2014). Clinical relevance of positive voltage-gated potassium channel (VGKC)-complex antibodies: Experience from a tertiary referral centre. Journal of Neurology, Neurosurgery and Psychiatry, 85(6), 625 - 630. doi:10.1136/jnnp-2013-305218
    • Harper L, Schott JM, Fox NC, Barkhof F, Scheltens P (2014). An algorithmic approach to structural imaging in dementia. Journal of Neurology, Neurosurgery and Psychiatry, 85(6), 692 - 698. doi:10.1136/jnnp-2013-306285
    • Jackson GS, Burk-Rafel J, Edgeworth JA, Sicilia A, Abdilahi S, Korteweg J, Mackey J, Thomas C, Wang G, Schott JM, Mummery C, Chinnery PF, Mead S, Collinge J (2014). Population Screening for Variant Creutzfeldt-Jakob Disease Using a Novel Blood Test: Diagnostic Accuracy and Feasibility Study.. JAMA Neurol, , - . doi:10.1001/jamaneurol.2013.6001
    • Andreasson U, Lautner R, Schott JM, Mattsson N, Hansson O, Herukka SK, Helisalmi S, Ewers M, Hampel H, Wallin A, Minthon L, Hardy J, Blennow K, Zetterberg H (2014). CSF biomarkers for Alzheimer's pathology and the effect size of APOE ɛ4.. Mol Psychiatry, 19(2), 148 - 149. doi:10.1038/mp.2013.18
    • Andreasson U, Lautner R, Mattsson N, Wallin A, Blennow K, Zetterberg H, Schott JM, Hardy J, Hansson O, Minthon L, Herukka S-K, Helisalmi S, Ewers M, Hampel H (2014). CSF biomarkers for Alzheimer's pathology and the effect size of APOE ε4. Molecular Psychiatry, 19(2), 148 - 149. doi:10.1038/mp.2013.18
    • Mahoney CJ, Ridgway GR, Malone IB, Downey LE, Beck J, Kinnunen KM, Schmitz N, Golden HL, Rohrer JD, Schott JM, Rossor MN, Ourselin S, Mead S, Fox NC, Warren JD (2014). Profiles of white matter tract pathology in frontotemporal dementia.. Hum Brain Mapp, , - . doi:10.1002/hbm.22468
    • Downey LE, Fletcher PD, Golden HL, Mahoney CJ, Agustus JL, Schott JM, Rohrer JD, Beck J, Mead S, Rossor MN, Crutch SJ, Warren JD (2014). Altered body schema processing in frontotemporal dementia with C9ORF72 mutations.. J Neurol Neurosurg Psychiatry, , - . doi:10.1136/jnnp-2013-306995
    • Toombs J, Paterson RW, Schott JM, Zetterberg H (2014). Amyloid-beta 42 adsorption following serial tube transfer.. Alzheimers Res Ther, 6(1), 5 - . doi:10.1186/alzrt236
    • Young AL, Oxtoby NP, Daga P, Cash DM, Fox NC, Ourselin S, Schott JM, Alexander DC, on behalf of the Alzheimer’s Disease Neuroimaging Initiative (2014). A data-driven model of biomarker changes in sporadic Alzheimer's disease.. Brain, , - . doi:10.1093/brain/awu176

    2013

    • Ahmed RM, Murphy E, Davagnanam I, Parton M, Schott JM, Mummery CJ, Rohrer JD, Lachmann RH, Houlden H, Fox NC, Chataway J (2013). A practical approach to diagnosing adult onset leucodystrophies.. J Neurol Neurosurg Psychiatry, , - . doi:10.1136/jnnp-2013-305888
    • Lehmann M, Koedam EL, Barnes J, Bartlett JW, Barkhof F, Wattjes MP, Schott JM, Scheltens P, Fox NC, Alzheimer's Disease Neuroimaging Initiative (2013). Visual ratings of atrophy in MCI: prediction of conversion and relationship with CSF biomarkers.. Neurobiol Aging, 34(1), 73 - 82. doi:10.1016/j.neurobiolaging.2012.03.010
    • Irani SR, Stagg CJ, Schott JM, Rosenthal CR, Schneider SA, Pettingill P, Pettingill R, Waters P, Thomas A, Voets NL, Cardoso MJ, Cash DM, Manning EN, Lang B, Smith SJ, Vincent A, Johnson MR (2013). Faciobrachial dystonic seizures: the influence of immunotherapy on seizure control and prevention of cognitive impairment in a broadening phenotype.. Brain, , - . doi:10.1093/brain/awt212
    • Crutch SJ, Schott JM, Lehmann M, Ryan NS, Shakespeare T, Fox NC, Rabinovici GD, Boeve BF, Cappa SF, Dickerson BC, Dubois B, Graff-Radford NR, Krolak-Salmon P, Mendez MF, Pijnenburg Y, Scheltens P, Van Der Flier WM, Tang-Wai DF, Bain L, Carrillo MC (2013). Shining a light on posterior cortical atrophy. Alzheimer's and Dementia, 9(4), 463 - 465. doi:10.1016/j.jalz.2012.11.004
    • Toombs J, Paterson RW, Lunn MP, Nicholas JM, Fox NC, Chapman MD, Schott JM, Zetterberg H (2013). Identification of an important potential confound in CSF AD studies: aliquot volume.. Clin Chem Lab Med, , 1 - 7. doi:10.1515/cclm-2013-0293
    • Paterson RW, Schott JM, Zandi MS, Armstrong R, Vincent A (2013). Clinical relevance of positive voltage-gated potassium channel (VGKC)-complex antibodies: Experience from a tertiary referral centre. Journal of Neurology, Neurosurgery and Psychiatry, , - . doi:10.1136/jnnp-2013-305218
    • Pertzov Y, Miller TD, Gorgoraptis N, Caine D, Schott JM, Butler C, Husain M (2013). Binding deficits in memory following medial temporal lobe damage in patients with voltage-gated potassium channel complex antibody-associated limbic encephalitis.. Brain, , - . doi:10.1093/brain/awt129
    • Fletcher PD, Downey LE, Agustus JL, Hailstone JC, Tyndall MH, Cifelli A, Schott JM, Warrington EK, Warren JD (2013). Agnosia for accents in primary progressive aphasia.. Neuropsychologia, , - . doi:10.1016/j.neuropsychologia.2013.05.013
    • Beck J, Poulter M, Hensman D, Rohrer JD, Mahoney CJ, Adamson G, Campbell T, Uphill J, Borg A, Fratta P, Orrell RW, Malaspina A, Rowe J, Brown J, Hodges J, Sidle K, Polke JM, Houlden H, Schott JM, Fox NC, Rossor MN, Tabrizi SJ, Isaacs AM, Hardy J, Warren JD, Collinge J, Mead S (2013). Large C9orf72 hexanucleotide repeat expansions are seen in multiple neurodegenerative syndromes and are more frequent than expected in the UK population.. Am J Hum Genet, 92(3), 345 - 353. doi:10.1016/j.ajhg.2013.01.011
    • Crutch SJ, Schott JM, Rabinovici GD, Boeve BF, Cappa SF, Dickerson BC, Dubois B, Graff-Radford NR, Krolak-Salmon P, Lehmann M, Mendez MF, Pijnenburg Y, Ryan NS, Scheltens P, Shakespeare T, Tang-Wai DF, van der Flier WM, Bain L, Carrillo MC, Fox NC (2013). Shining a light on posterior cortical atrophy.. Alzheimers Dement, 9(4), 463 - 465. doi:10.1016/j.jalz.2012.11.004
    • Scahill RI, Ridgway GR, Barnes J, Ryan NS, Clarkson MJ, Foster J, Crutch SJ, Schott JM, Ourselin S, Warren JD, Hardy J, Rossor MN, Fox NC (2013). Genetic influences on atrophy patterns in familial AD: a comparason of APP and PSEN-1 mutations. Journal of AD, 35, 199 - 212. doi:10.3233/JAD-121255
    • Liang Y, Ryan NS, Schott JM, Fox NC (2013). Imaging the onset and progression of Alzheimer's disease: implications for prevention trials.. J Alzheimers Dis, 33 Suppl 1, S305 - S312. doi:10.3233/JAD-2012-129010
    • Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, Jun G, Destefano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thornton-Wells TA, Jones N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Gerrish A, Schmidt H, Kunkle B, Dunstan ML, Ruiz A, Bihoreau MT, Choi SH, Reitz C, Pasquier F, Hollingworth P, Ramirez A, Hanon O, Fitzpatrick AL, Buxbaum JD, Campion D, Crane PK, Baldwin C, Becker T, Gudnason V, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, Morón FJ, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, Fiévet N, Huentelman MJ, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuinness B, Larson EB, Green R, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, St George-Hyslop P, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, Bossù P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Sanchez-Garcia F, Fox NC, Hardy J, Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Mancuso M, Matthews F, European Alzheimer's Disease Initiative (EADI) , Genetic and Environmental Risk in Alzheimer's Disease (GERAD) , Alzheimer's Disease Genetic Consortium (ADGC) , Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) , Moebus S, Mecocci P, Del Zompo M, Maier W, Hampel H, Pilotto A, Bullido M, Panza F, Caffarra P, Nacmias B, Gilbert JR, Mayhaus M, Lannfelt L, Hakonarson H, Pichler S, Carrasquillo MM, Ingelsson M, Beekly D, Alvarez V, Zou F, Valladares O, Younkin SG, Coto E, Hamilton-Nelson KL, Gu W, Razquin C, Pastor P, Mateo I, Owen MJ, Faber KM, Jonsson PV, Combarros O, O'Donovan MC, Cantwell LB, Soininen H, Blacker D, Mead S, Mosley TH, Bennett DA, Harris TB, Fratiglioni L, Holmes C, de Bruijn RF, Passmore P, Montine TJ, Bettens K, Rotter JI, Brice A, Morgan K, Foroud TM, Kukull WA, Hannequin D, Powell JF, Nalls MA, Ritchie K, Lunetta KL, Kauwe JS, Boerwinkle E, Riemenschneider M, Boada M, Hiltunen M, Martin ER, Schmidt R, Rujescu D, Wang LS, Dartigues JF, Mayeux R, Tzourio C, Hofman A, Nöthen MM, Graff C, Psaty BM, Jones L, Haines JL, Holmans PA, Lathrop M, Pericak-Vance MA, Launer LJ, Farrer LA, van Duijn CM, Van Broeckhoven C, Moskvina V, Seshadri S, Williams J, Schellenberg GD, Amouyel P (2013). Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.. Nat Genet, , - . doi:10.1038/ng.2802
    • Rossor M, Ahmed R, Liang Y, Douglas J, Mahoney C, Warren J, Schott J, Fox N (2013). LONGITUDINAL RESEARCH INTO ALZHEIMER'S DISEASE, FRONTO-TEMPORAL DEMENTIA AND OTHER DEMENTIAS.. J Neurol Neurosurg Psychiatry, 84(11), e2 - . doi:10.1136/jnnp-2013-306573.68
    • Rohrer JD, Gordon E, Fox NC, Warren JD, Rossor MN, Schott JM, Beck J, Mead S, Plagnol V, Lashley T, Revesz T, Janssen JC (2013). Exome sequencing reveals a novel partial deletion in the progranulin gene causing primary progressive aphasia. Journal of Neurology, Neurosurgery and Psychiatry, 84(12), 1411 - 1412. doi:10.1136/jnnp-2013-306116
    • Schott JM (2013). HIV testing in dementia: test some, perhaps more, but not all.. Pract Neurol, 13(6), 357 - 358. doi:10.1136/practneurol-2013-000746
    • Beck J, Adamson G, Campbell T, Uphill J, Poulter M, Collinge J, Mead S, Pittman A, Houlden H, Shoai M, Hardy J, Kenny J, Rohrer JD, Mummery CJ, Warren JD, Schott JM, Fox NC, Rossor MN, de Silva R (2013). Validation of next-generation sequencing technologies in genetic diagnosis of dementia. Neurobiology of Aging, , - . doi:10.1016/j.neurobiolaging.2013.07.017
    • Harper L, Barkhof F, Scheltens P, Schott JM, Fox NC (2013). An algorithmic approach to structural imaging in dementia.. J Neurol Neurosurg Psychiatry, , - . doi:10.1136/jnnp-2013-306285
    • Warren JD, Rohrer JD, Schott JM, Fox NC, Rossor MN, Hardy J (2013). Molecular nexopathies: A new paradigm of neurodegenerative disease. Trends in Neurosciences, 36(10), 561 - 569. doi:10.1016/j.tins.2013.06.007
    • Schott JM, Revesz T (2013). Inflammation in Alzheimer's disease: insights from immunotherapy.. Brain, 136(Pt 9), 2654 - 2656. doi:10.1093/brain/awt231
    • Magdalinou NK, Ling H, Lees AJ, Schott JM, Smith JDS, Watkins LD (2013). Normal pressure hydrocephalus or progressive supranuclear palsy? A clinicopathological case series. Journal of Neurology, 260(4), 1009 - 1013. doi:10.1007/s00415-012-6745-6
    • Mahoney CJ, Malone IB, Ridgway GR, Buckley AH, Downey LE, Golden HL, Ryan NS, Ourselin S, Schott JM, Rossor MN, Fox NC, Warren JD (2013). White matter tract signatures of the progressive aphasias. Neurobiology of Aging, 34(6), 1687 - 1699. doi:10.1016/j.neurobiolaging.2012.12.002
    • Andrews KA, Modat M, Macdonald KE, Yeatman T, Cardoso MJ, Leung KK, Barnes J, Villemagne VL, Rowe CC, Fox NC, Ourselin S, Schott JM, the Australian Imaging Biomarkers , Lifestyle Flagship Study of Ageing (2013). Atrophy Rates in Asymptomatic Amyloidosis: Implications for Alzheimer Prevention Trials. PLoS ONE, 8(3), e58816 - . doi:10.1371/journal.pone.0058816
    • Barnes J, Carmichael OT, Leung KK, Schwarz C, Ridgway GR, Bartlett JW, Malone IB, Schott JM, Rossor MN, Biessels GJ, DeCarli C, Fox NC, Alzheimer's Disease Neuroimaging Initiative (2013). Vascular and Alzheimer's disease markers independently predict brain atrophy rate in Alzheimer's Disease Neuroimaging Initiative controls.. Neurobiol Aging, 34(8), 1996 - 2002. doi:10.1016/j.neurobiolaging.2013.02.003
    • Liang Y, Ryan NS, Schott JM, Fox NC (2013). Imaging the onset and progression of Alzheimer's disease: Implications for prevention trials. Journal of Alzheimer's Disease, 33(SUPPL. 1), - . doi:10.3233/JAD-2012-129010
    • Malone IB, Cash D, Ridgway GR, MacManus DG, Ourselin S, Fox NC, Schott JM (2013). MIRIAD--Public release of a multiple time point Alzheimer's MR imaging dataset.. Neuroimage, 70, 33 - 36. doi:10.1016/j.neuroimage.2012.12.044
    • Barnes J, Bartlett JW, Fox NC, Schott JM (2013). Targeted recruitment using cerebrospinal fluid biomarkers: implications for Alzheimer's disease therapeutic trials.. J Alzheimers Dis, 34(2), 431 - 437. doi:10.3233/JAD-121936
    • Lehmann M, Barnes J, Bartlett JW, Schott JM, Scheltens P, Fox NC, Koedam EL, Barkhof F, Wattjes MP (2013). Visual ratings of atrophy in MCI: Prediction of conversion and relationship with CSF biomarkers. Neurobiology of Aging, 34(1), 73 - 82. doi:10.1016/j.neurobiolaging.2012.03.010
    • Paterson RW, Toombs J, Slattery CF, Schott JM, Zetterberg H (2013). Biomarker Modelling of Early Molecular Changes in Alzheimer's Disease.. Mol Diagn Ther, , - . doi:10.1007/s40291-013-0069-9

    2012

    • Ryan NS, Rohrer JD, Fox NC, Rossor MN, Schott JM, Bastos-Leite AJ, Werring DJ (2012). Cerebral microbleeds in familial Alzheimer's disease. Brain, 135(1), - . doi:10.1093/brain/awr126
    • Schott JM (2012). Voltage gated potassium channel complex antibody associated limbic encephalitis.
    • Schott JM, IEEE (2012). MRI BIOMARKERS IN NEURODEGENERATIVE DISORDERS.
    • Schott JM, Warren JD (2012). Alzheimer's disease: mimics and chameleons.. Pract Neurol, 12(6), 358 - 366. doi:10.1136/practneurol-2012-000315
    • Magdalinou NK, Ling H, Schott JM, Lees AJ (2012). Normal pressure hydorcephalus or progressive supranuclear palsy? A clinicopathological case series.
    • Schott JM, Bartlett JW (2012). Investigating missing data in Alzheimer disease studies.. Neurology, 78(18), 1370 - 1371. doi:10.1212/WNL.0b013e318253d66b
    • Schrag A, Schott JM, Alzheimer's Disease Neuroimaging Initiative (2012). What is the clinically relevant change on the ADAS-Cog?. J Neurol Neurosurg Psychiatry, 83(2), 171 - 173. doi:10.1136/jnnp-2011-300881
    • Ryan N, Biessels G, Bastos-Leite A, Beck J, Mead S, Morris H, Schott JM, Rossor MN, Fox NC (2012). WHITE MATTER LESIONS IN FAMILIAL ALZHEIMER'S DISEASE: EVIDENCE FOR INFLUENCE OF MUTATION POSITION ON AMYLOID ANGIOPATHY?. doi:10.1136/jnnp-2011-301993.1
    • Crutch SJ, Lehmann M, Schott JM, Rabinovici GD, Rossor MN, Fox NC (2012). Posterior cortical atrophy.. Lancet Neurol, 11(2), 170 - 178. doi:10.1016/S1474-4422(11)70289-7
    • Bartlett JW, Frost C, Zetterberg H, Schott JM, Mattsson N, Skillbäck T, Blennow K (2012). Determining cut-points for Alzheimers disease biomarkers: Statistical issues, methods and challenges. Biomarkers in Medicine, 6(4), 391 - 400. doi:10.2217/bmm.12.49
    • Mahoney CJ, Beck J, Rohrer JD, Lashley T, Mok K, Shakespeare T, Yeatman T, Warrington EK, Schott JM, Fox NC, Rossor MN, Hardy J, Collinge J, Revesz T, Mead S, Warren JD (2012). Frontotemporal dementia with the C9ORF72 hexanucleotide repeat expansion: clinical, neuroanatomical and neuropathological features.. Brain, 135(Pt 3), 736 - 750. doi:10.1093/brain/awr361
    • Warren J, Rohrer JD, Lashley T, Schott JM, Beck J, Mead S, Fox NC, Revesz T, Hardy J, Rossor MN (2012). The frontotemporal lobar degenerations as 'molecular nexopathies'.
    • Schott JM (2012). Using CSF biomarkers to replicate genetic associations in Alzheimer's disease. Neurobiology of Aging, 33(7), - . doi:10.1016/j.neurobiolaging.2011.02.008
    • Schrag A, Schott JM (2012). Images in clinical medicine. Kayser-Fleischer rings in Wilson's disease.. N Engl J Med, 366(12), e18 - . doi:10.1056/NEJMicm1101534

    2011

    • Irani SR, Michell AW, Johnson MR, Schott JM, Somerville ER, Vincent A, Smith SM (2011). Reply.. Ann Neurol, 70(1), 180 - . doi:10.1002/ana.22471
    • Schott JM (2011). Using CSF biomarkers to replicate genetic associations in Alzheimer's disease. Neurobiology of Aging, , - .
    • Irani SR, Lang B, Pettingill P, Waters P, Armstrong RJE, Vincent A, Michell AW, Johnson MR, Schott JM, S Zagami A, Somerville ER, Bleasel A, Smith SMJ (2011). Faciobrachial dystonic seizures precede Lgi1 antibody limbic encephalitis. Annals of Neurology, 69(5), 892 - 900. doi:10.1002/ana.22307
    • Rohrer JD, Schott JM (2011). Primary progressive aphasia-defining genetic and pathological subtypes. Current Alzheimer Research, 8(3), 266 - 272. doi:10.2174/156720511795563728
    • Irani SR, Schott JM, Vincent A, Smith SJ (2011). Tonic seizures: a diagnostic clue of anti-LGI1 encephalitis?. Neurology, 77(24), 2140 - 2141.
    • Schott JM, Warren JD, Barkhof F, Rossor MN, Fox NC (2011). RATIONAL IMAGING Suspected early dementia. BRIT MED J, 343, - . doi:10.1136/bmj.d5568
    • Schott JM (2011). Spectra to identify the spectre of Alzheimer disease?. Neurology, 77(10), 932 - 933. doi:10.1212/WNL.0b013e31822cfce6
    • Irani SR, Michell AW, Johnson MR, Schott JM, Somerville ER, Vincent A, Smith SMJ (2011). Faciobrachial Dystonic Attacks: Seizures or Movement Disorder? Reply. ANN NEUROL, 70(1), 180 - 180. doi:10.1002/ana.22471
    • Schott JM, Warren JD, Rossor MN, Revesz T (2011). Open biopsy in patients with acute progressive neurologic decline and absence of mass lesion.. Neurology, 76(21), 1847 - . doi:10.1212/WNL.0b013e318210e621
    • Irani SR, Michell AW, Lang B, Pettingill P, Waters P, Johnson MR, Schott JM, Armstrong RJE, Zagami AS, Bleasel A, Somerville ER, Smith SMJ, Vincent A (2011). Faciobrachial Dystonic Seizures Precede Lgi1 Antibody Limbic Encephalitis. ANN NEUROL, 69(5), 892 - 900. doi:10.1002/ana.22307
    • Irani SR, Vincent A, Schott JM (2011). Autoimmune encephalitis. BRIT MED J, 342, - . doi:10.1136/bmj.d1918
    • Fox NC, Ridgway GR, Schott JM (2011). Algorithms, atrophy and Alzheimer's disease: cautionary tales for clinical trials.. Neuroimage, 57(1), 15 - 18. doi:10.1016/j.neuroimage.2011.01.077
    • Irani SR, Vincent A, Schott JM (2011). Autoimmune encephalitis.. BMJ, 342, d1918 - .
    • Revesz T, Schott JM, Reiniger L, Thom M, Holton JL, Grieve J, Brandner S, Warren JD (2011). Brain biopsy in dementia: clinical indications and neuropathological diagnostic approach.
    • Anderson V, Schott J, Bartlett J, Leung KK, Miller DH, Fox NC (2011). Grey matter atrophy rate as a marker of disease progression in AD. Neurobiology of Aging, , - . doi:10.1016/j.neurobiolaging.2010.11.001
    • Schott JM, Warren JD, Rossor MN, Fox NC, Barkhof F (2011). Suspected early dementia. BMJ (Online), 343(7824), - . doi:10.1136/bmj.d5568
    • Rohrer JD, Lashley T, Schott JM, Warren JE, Mead S, Isaacs AM, Beck J, Hardy J, de Silva R, Warrington E, Troakes C, Al-Sarraj S, King A, Borroni B, Clarkson M, Ourselin S, Holton J, Fox NC, Revesz T, Rossor MN, Warren JD (2011). Clinical and neuroanatomical signatures of tissue pathology in frontotemporal lobar degeneration. Brain, 134(9), 2565 - 2581.

    2010

    • Anderson VM, Schott JM, Bartlett JW, Leung KK, Miller DH, Fox NC (2010). Gray matter atrophy rate as a marker of disease progression in AD. Neurobiology of Aging, , - .
    • Revesz T, Schott JM, Holton JL, Reiniger L, Brandner S, Thom M, Warren JD (2010). Brain biopsy in dementia - clinical indications and diagnostic approach.
    • Schott JM, Frost C, MacManus DG, Ibrahim F, Waldman AD, Fox NC (2010). Short echo time proton magnetic resonance spectroscopy in Alzheimer's disease: a longitudinal multiple time point study.. Brain, 133(11), 3315 - 3322. doi:10.1093/brain/awq208
    • Schott JM, Bartlett JW, Fox NC, Barnes J (2010). Increased brain atrophy rates in cognitively normal older adults with low cerebrospinal fluid Aβ1-42. Annals of Neurology, 68(6), 825 - 834. doi:10.1002/ana.22315
    • Guerreiro RJ, Beck J, Gibbs JR, Santana I, Rossor MN, Schott JM, Nalls MA, Ribeiro H, Santiago B, Fox NC, Oliveira C, Collinge J, Mead S, Singleton A, Hardy J (2010). Genetic variability in CLU and its association with Alzheimer's disease.. PLoS One, 5(3), e9510 - . doi:10.1371/journal.pone.0009510
    • Schott JM, Reiniger L, Thom M, Holton JL, Grieve J, Brandner S, Warren JD, Revesz T (2010). Brain biopsy in dementia: clinical indications and diagnostic approach.. Acta Neuropathol, 120(3), 327 - 341. doi:10.1007/s00401-010-0721-y
    • Schott JM, Bartlett JW, Barnes J, Leung KK, Ourselin S, Fox NC (2010). Reduced sample sizes for atrophy outcomes in Alzheimer's disease trials: baseline adjustment. Neurobiol Aging, 31(8), 1452 - 1462.e2.
    • Rossor MN, Fox NC, Mummery CJ, Schott JM, Warren JD (2010). The diagnosis of young-onset dementia.. Lancet Neurol, 9(8), 793 - 806. doi:10.1016/S1474-4422(10)70159-9
    • Tolboom N, Koedam EL, Schott JM, Yaqub M, Blankenstein MA, Barkhof F, Pijnenburg YA, Lammertsma AA, Scheltens P, van Berckel BN (2010). Dementia mimicking Alzheimer's disease Owing to a tau mutation: CSF and PET findings.. Alzheimer Dis Assoc Disord, 24(3), 303 - 307. doi:10.1097/WAD.0b013e3181cf35ec
    • Schott JM, Bartlett JW, Fox NC, Barnes J, Alzheimer's Disease Neuroimaging Initiative Investigators (2010). Increased brain atrophy rates in cognitively normal older adults with low cerebrospinal fluid Aβ1-42.. Ann Neurol, 68(6), 825 - 834. doi:10.1002/ana.22315

    2009

    • Gutiérrez-Galve L, Lehmann M, Hobbs NZ, Clarkson MJ, Ridgway GR, Crutch S, Ourselin S, Schott JM, Fox NC, Barnes J (2009). Patterns of cortical thickness according to APOE genotype in Alzheimer's disease.. Dement Geriatr Cogn Disord, 28(5), 476 - 485. doi:10.1159/000258100

    2008

    • Gallagher DA, Schott JM, Childerhouse A, Wilhelm T, Gale AN, Schrag A (2008). Reversible "Applause sign" secondary to diffuse large B cell lymphoma. Movement Disorders, 23(16), 2426 - 2428. doi:10.1002/mds.22311
    • Barnes J, Scahill RI, Frost C, Schott JM, Rossor MN, Fox NC (2008). Increased hippocampal atrophy rates in AD over 6 months using serial MR imaging. NEUROBIOL AGING, 29(8), 1199 - 1203. doi:10.1016/j.neurobiolaging.2007.02.01
    • Schott JM (2008). Ischemic bilateral hippocampal dysfunction during transient global amnesia.. Neurology, 70(20), 1940 - . doi:10.1212/01.wnl.0000314641.73292.d3
    • Barnes J, Foster J, Boyes RG, Pepple T, Moore EK, Schott JM, Frost C, Scahill RI, Fox NC (2008). A comparison of methods for the automated calculation of volumes and atrophy rates in the hippocampus. NeuroImage, 40(4), 1655 - 1671. doi:10.1016/j.neuroimage.2008.01.012
    • Schott JM, Crutch SJ, Frost C, Warrington EK, Rossor MN, Fox NC (2008). Neuropsychological correlates of whole brain atrophy in Alzheimer's disease. Neuropsychologia, 46(6), 1732 - 1737. doi:10.1016/j.neuropsychologia.2008.02.015

    2007

    • Ridha BH, Barnes J, van de Pol LA, Schott JM, Boyes RG, Siddique MM, Rossor MN, Scheltens P, Fox NC (2007). Application of automated medial temporal lobe atrophy scale to Alzheimer disease. Archives of Neurology, 64(6), 849 - 854. doi:10.1001/archneur.64.6.849
    • Schott JM (2007). A neurological MRI menagerie. Practical Neurology, 7(3), 186 - 190. doi:10.1136/jnnp.2007.120261
    • Smith SM, Rao A, De Stefano N, Jenkinson M, Schott JM, Matthews PM, Fox NC (2007). Longitudinal and cross-sectional analysis of atrophy in Alzheimer's disease: Cross-validation of BSI, SIENA and SIENAX. NeuroImage, 36(4), 1200 - 1206. doi:10.1016/j.neuroimage.2007.04.035
    • Barnes J, Lewis EB, Scahill RI, Bartlett JW, Frost C, Schott JM, Rossor MN, Fox NC (2007). Automated measurement of hippocampal atrophy using fluid-registered serial MRI in AD and controls. Journal of Computer Assisted Tomography, 31(4), 581 - 587.
    • Barnes J, Boyes RG, Lewis EB, Schott JM, Frost C, Scahill RI, Fox NC (2007). Automatic calculation of hippocampal atrophy rates using a hippocampal template and boundary shift integral.. Neurobiology of Aging, 28(11), 1657 - 1663. doi:10.1016/j.neurobiolaging.2006.07.008
    • Schott JM, Williams DR, Butterworth RJ, Janssen JC, Larner AJ, Holton JL, Rossor MN (2007). Shunt responsive progressive supranuclear palsy?. Movement Disorders, 22(6), 902 - 903. doi:10.1002/mds.21404
    • Schott JM, Warren JD (2007). Steroid responsive encephalopathy with positive thyroid antibodies. A syndrome, not a diagnosis?. Journal of Neurology, 254(4), 542 - . doi:10.1007/s00415-006-0279-8

    2006

    • Garrard P, Schott JM, MacManus DG, Hodges JR, Fox NC, Waldman AD (2006). Posterior cingulate neurometabolite profiles and clinical phenotype in frontotemporal dementia.. Cogn Behav Neurol, 19(4), 185 - 189. doi:10.1097/01.wnn.0000213915.72395.77
    • Boyes RG, Rueckert D, Aljabar P, Whitwell J, Schott JM, Hill DL, Fox NC (2006). Cerebral atrophy measurements using Jacobian integration: Comparison with the boundary shift integral. NeuroImage, 32(1), 159 - 169.
    • Schott JM (2006). Limbic encephalitis: a clinician's guide. Practical Neurology, 6, 143 - 153.
    • Schott JM (2006). Another case of voltage-gated potassium channel antibody-related encephalopathy?. European Neurology, 55(2), 110 - 110. doi:10.1159/000092787
    • Godbolt AK, Waldman AD, MacManus DG, Schott JM, Frost C, Cipolotti L, Fox NC, Rossor MN (2006). MRS shows abnormalities before symptoms in familial Alzheimer disease. Neurology, 66(5), 718 - 722.
    • Schott JM, Ridha BH, Crutch SJ, Healy DG, Uphill JB, Warrington EK, Rossor MN, Fox NC (2006). Apolipoprotein E genotype modifies the phenotype of Alzheimer disease. Archives of Neurology, 63(1), 155 - 156.
    • Schott JM, Kennedy J, Fox NC (2006). New developments in mild cognitive impairment and Alzheimer's disease. Current Opinion in Neurology, 19(6), 552 - 558.
    • Schott JM, Frost C, Whitwell JL, MacManus DG, Boyes RG, Rossor MN, Fox NC (2006). Combining short interval MRI in Alzheimer's disease : Implications for therapeutic trials. Journal of Neurology, 253(9), 1147 - 1153.
    • Schrag A, Schott JM (2006). Epidemiological, clinical, and genetic characteristics of early-onset parkinsonism. The Lancet Neurology, 5(4), 355 - 363.

    2005

    • Schott GD, Schott JM (2005). Etiology of mirror writing in Japanese - In reply. Archives of Neurology, 62(5), 835 - 835.
    • Barnes J, Scahill RI, Schott JM, Frost C, Rossor MN, Fox NC (2005). Does Alzheimer's disease affect hippocampal asymmetry? Evidence from a cross-sectional and longitudinal volumetric MRI study. Dementia and Geriatric Cognitive Disorders, 19(5-6), 338 - 344.
    • Janssen JC, Schott JM, Cipolotti L, Fox NC, Scahill RI, Josephs KA, Stevens JM, Rossor MN (2005). Mapping the onset and progression of atrophy in familial frontotemporal lobar degeneration. Journal of Neurology, Neurosurgery and Psychiatry, 76(2), 162 - 168.
    • Archer HA, Schott JM, Barnes J, Fox NC, Holton JL, Revesz T, Cipolotti L, Rossor MN (2005). Knight's move thinking? Mild cognitive impairment in a chess player. Neurocase, 11(1), 26 - 31.
    • Warren JD, Schott JM, Fox NC, Thom M, Revesz T, Holton JL, Scaravilli F, Thomas DG, Plant GT, Rudge P, Rossor MN (2005). Brain biopsy in dementia. Brain, 128(9), 2016 - 2025. doi:10.1093/brain/awh543
    • Schott JM, Price SL, Frost C, Whitwell JL, Rossor MN, Fox NC (2005). Measuring atrophy in Alzheimer disease: a serial MRI study over 6 and 12 months. Neurology, 65(1), 119 - 124.
    • Schott JM, Warren JD, Fox NC, Thom M, Revesz T, Scaravilli F, Holton J, Thomas DGT, Plant GT, Rudge P, Rossor MN (2005). Brain biopsy in dementia: A review of 90 consecutive cases from Queen Square.
    • Ridha BH, Schott JM, Crutch SJ, Healy DG, Uphill JB, Warrington EW, Rossor MN, Fox NC (2005). Apoliprotein E genotype modifies the phenotype of Alzheimer's disease.

    2004

    • Fox NC, Schott JM, Scahill RI (2004). Measuring progression in Alzheimer's disease using serial MRI: 4D MRI. In Hyman B, Demonet JF, Christen Y (Ed.), The Living Brain and Alzheimer's Disease (pp. 61 - 74). : Springer-Verlag.
    • Boyes RG, Schott JM, Frost C, Fox NC (2004). Increasing accuracy of atrophy measures from serial MR scans using parameter analysis of the boundary shift integral. Lecture Notes In Computer Science, 3217, 1036 - 1037.
    • Fox N, Schott J, Barnes J, Price S, Anderson V, Whitwell J, Rossor M (2004). MRI to measure progression to AD and in AD.
    • Schott JM, Janssen JC, Cipolotti L, Fox NC, Scahill RI, Josephs KA, Stevens JM, Rossor MN (2004). Presymptomatic focal atrophy precedes speech production impairment in familial frontotemporal lobar degeneration.
    • Schott JM, Lees AJ, Rossor MN (2004). Dementia in dementia with Lewy bodies may not be attributable to Alzheimer pathology. Annals of Neurology, 56(4), 604 - 604. doi:10.1002/ana.20271
    • Paviour DC, Schott JM, Stevens JM, Revesz T, Holton JL, Rossor MN, Lees AJ, Fox NC (2004). Pathological substrate for regional distribution of increased atrophy rates in progressive supranuclear palsy. Journal of Neurology, Neurosurgery and Psychiatry, 75(12), 1772 - 1775.
    • Schott GD, Schott JM (2004). Mirror writing, left-handedness, and leftward scripts. Archives of Neurology, 61(12), 1849 - 1851.
    • Mahapatra RK, Edwards MJ, Schott JM, Bhatia KP (2004). Corticobasal degeneration. The Lancet Neurology, 3(12), 736 - 743.
    • Schott JM, Fox NC (2004). Structural imaging in the dementias. Psychiatry, 3(12), 22 - 26. doi:10.1383/psyt.3.12.22.56779
    • Fox NCI, Schott JM (2004). Imaging cerebral atrophy: normal ageing to Alzheimer's disease. The Lancet, 363(9406), 392 - 394. doi:10.1016/S0140-6736(04)15441-X
    • Scahill RI, Schott JM, Stevens JM, Janssen JC, Rossor MN, Fox NC (2004). Fluid registration of serial MRI: Identifying regional changes in Alzheimer's disease.
    • Schott JM, Fox NC, Frost C, Scahill RI, Chan D, Janssen JC, Jenkins R, Rossor MN (2004). Familial Alzheimer's disease: How early does medial temporal lobe atrophy occur?.
    • Vincent A, Buckley C, Schott JM, Baker I, Dewar BK, Detert N, Clover L, Parkinson A, Bien CG, Omer S, Lang B, Rossor MN, Palace J (2004). Potassium channel antibody-associated encephalopathy: a potentially immunotherapy-responsive form of limbic encephalitis. Brain, 127(3), 701 - 712.
    • Schott JM, Vincent A, Clover L, Buckley C, Gabel A, Lang B, Omer S, Bien CG, Palace J, Rossor MN (2004). Potassium channel antibody associated encephalitis: A potentially treatable non-paraneoplastic limbic encephalitis.
    • Chan D, Walters RJ, Sampson EL, Schott JM, Smith SJ, Rossor MN (2004). EEG abnormalities in frontotemporal lobar degeneration. Neurology, 62(9), 1628 - 1630.
    • Fox NC, Schott JM, Frost C, Rossor MN (2004). Serial magnetic resonance imaging as an outcome measure in dementia.
    • Whitwell JL, Schott JM, Lewis EB, MacManus DG, Fox NC (2004). Using nine degrees-of-freedom registration to correct for changes in voxel size in serial MRI studies. Magnetic Resonance Imaging, 22(7), 993 - 999.
    • Schott JM, Frost C, Crutch SJ, Boyes RG, Whitwell JL, Scahill RI, Rossor MN, Warrington EK, Fox NC (2004). Predictors and correlates of inter-individual variation in MRI derived atrophy rates in Alzheimer's disease.

    2003

    • Schott JM, Harkness K, Barnes J, Della Rocchetta AI, Vincent A, Rossor MN (2003). Amnesia, cerebral atrophy, and autoimmunity. The Lancet, 361(9365), 1266 - 1266. doi:10.1016/S0140-6736(03)12983-2
    • Schott JM, Fox NC, Frost C, Scahill RI, Janssen JC, Chan D, Jenkins R, Rossor MN (2003). Assessing the onset of structural change in familial Alzheimer's disease. Annals of Neurology, 53(2), 181 - 188. doi:10.1002/ana.10424
    • Schott JM, Rossor MN (2003). The grasp and other primitive reflexes. Journal of Neurology, Neurosurgery and Psychiatry, 74(5), 558 - 560.
    • Schott JM, Warren JD, Rossor MN (2003). The uncertain nosology of Hashimoto encephalopathy.. Arch Neurol, 60(12), 1812 - . doi:10.1001/archneur.60.12.1812-a
    • Walters RJL, Fox NC, Schott JM, Crum WR, Stevens JM, Rossor MN, Thomas DJ (2003). Transient ischaemic attacks are associated with increased rates of global cerebral atrophy. Journal of Neurology, Neurosurgery and Psychiatry, 74(2), 213 - 216.
    • Schott JM, Simon JE, Fox NC, King AP, Khan MN, Cipolotti L, Paviour DC, Stevens JM, Rossor MN (2003). Delineating the sites and progression of in vivo atrophy in multiple system atrophy using fluid-registered MRI. Movement Disorders, 18(8), 955 - 958.
    • Schott JM, Crutch SJ, Fox NC, Warrington EK (2003). Development of selective verbal memory impairment secondary to a left thalamic infarct: a longitudinal case study. Journal of Neurology, Neurosurgery and Psychiatry, 74(2), 255 - 257.

    2002

    • Janssen JC, Scahill RI, Schott JM, Whitwell J, Warrington E, Rossor MN, Fox NC, Stevens JM, Cipolotti L (2002). In vivo mapping of the onset and progression of neurodegeneration in frontotemporal lobar degeneration. NEUROBIOL AGING, 23(1), S479 - S479.
    • Schott JM, Fox NC, Rossor MN (2002). Genetics of the dementias.. J Neurol Neurosurg Psychiatry, 73 Suppl 2, II27 - II31.
    • Scahill RI, Schott JM, Stevens JM, Rossor MN, Fox NC (2002). Mapping the evolution of regional atrophy in Alzheimer's disease: unbiased analysis of fluid-registered serial MRI. Proceedings of the National Academy of Sciences of the United States of America, 99(7), 4703 - 4707. doi:10.1073/pnas.052587399

    2000

    • Rigby SP, Schott JM, Bliss P, Higgens CS, Kamm MA (2000). Dilated stomach and weak muscles. Lancet, 356(9245), 1898 - 1898.

    1999

    • Schott JM, Rigby SP, McNally JD, Keat A, Higgens CS (1999). Oral methotrexate: the hazard of different tablet strengths.. Rheumatology (Oxford), 38(4), 382 - .

    1995

    • Schott J, McCully K, Rutherford OM (1995). The role of metabolites in strength training. II. Short versus long isometric contractions.. Eur J Appl Physiol Occup Physiol, 71(4), 337 - 341.
    • Schott J, Puttick M (1995). Handedness among surgeons.. BMJ, 310(6981), 739 - .
    • Rutherford OM, Beshyah SA, Schott J, Watkins Y, Johnston DG (1995). Contractile properties of the quadriceps muscle in growth hormone-deficient hypopituitary adults.. Clin Sci (Lond), 88(1), 67 - 71.

    1994

    • SCHOTT J, RUTHERFORD O (1994). CHANGES IN FATIGUABILITY AND CONTRACTILE PROPERTIES OF THE HUMAN QUADRICEPS FOLLOWING ISOMETRIC STRENGTH TRAINING. JOURNAL OF PHYSIOLOGY-LONDON, 475P, P26 - P27.