Prof John Collinge

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Personal Profile

Name: John Collinge Email: j.collinge@ucl.ac.uk
Title: Prof Tel: 020 7837 4888
Department: Neurodegenerative Diseases Fax:
Position: Professor of Neurology Address: National Hospital for Neurology & Neurosurgery, UCL, Queen Square, London , WC1N 3BG
Research Domain: Basic Life Sciences, Neuroscience Web Page: Personal Web Page

Profile

Research Description

The Department of Neurodegenerative Disease’s research portfolio encompasses prion diseases (predominantly within the embedded MRC Prion Unit), Alzheimer’s disease and related disorders, Huntington’s disease, motor neurone disease and frontotemporal dementia and studies of the pathways of cellular senescence. The research philosophy is to combine basic and clinical translational research; many of the key contributions towards understanding the basic biology of these diseases have come from clinical and neuropathological observations, and efficient translation of basic laboratory research to the clinic is essential to provide benefits for patients at the earliest opportunity.

The MRC Prion Unit was established in 1998 and is located at the UCL Institute of Neurology where it is closely integrated with the University Department of Neurodegenerative Disease. The Unit was formed to provide a national centre of excellence with all necessary facilities to pursue a major long-term research strategy in prion and related diseases. 

Prions, unlike other infectious agents or germs, appear to lack their own genes and consist of aggregated misshapen forms of one of the body’s own proteins, the prion protein or PrP. Despite lacking genes, prions can exist as distinct strains with quite different properties. These unique features have wide implications in biology and evolution, and prions and prion diseases are of intense international research interest. However, in addition to the importance of this basic science, the Unit’s mission is also to tackle key public health issues posed by bovine spongiform encephalopathy (BSE) and variant Creutzfeldt-Jakob disease (vCJD).

It is becoming increasingly clear that other much commoner degenerative brain diseases, such as Alzheimer’s and Parkinson’s disease, also involve accumulation of rogue or abnormal forms of one or more of the body’s proteins resulting in damage to brain cells. Prion diseases, in addition to their intrinsic interest and importance, can be considered a paradigm for these other “protein misfolding” diseases. 

Our research programmes are highly multidisciplinary and focus both on areas of public health concern and a long-term approach to the understanding of prion disease. They include studies of molecular structure, genetics, biochemistry, immunology, cell and animal models, and clinical research - including treatment trials. Two major programmes to develop novel therapies are underway.


Research Activities

Cellular mechanisms underlying neurodegeneration

Neurodegenerative Disease

Neurological disease

Education Description

UCL Collaborators

Prof Parmjit Jat; Prof John Hardy; Prof Henry Houlden; Prof Andrew Lees; Prof Ivan Gout; Dr Simon Mead; Prof Kailash Bhatia; Prof Sarah Tabrizi; Dr Marc Soutar; Prof Nicholas Wood; Prof Martin Rossor; Dr Helene Plun-Favreau; Dr Stephanie Schorge; Prof Mike O'hare

External Collaborators

Publications

    2014

    • Thompson A, MacKay A, Rudge P, Lukic A, Porter M-C, Lowe J, Collinge J, Mead S (2014). Behavioural and Psychiatric Symptoms in Prion Disease. American Journal of Psychiatry, 171(3), 265 - 274. doi:10.1176/appi.ajp.2013.12111460
    • Thompson A, Mackay A, Rudge P, Lukic A, Porter MC, Lowe J, Collinge J, Mead S (2014). Behavioral and psychiatric symptoms in prion disease.. Am J Psychiatry, 171(3), 265 - 274. doi:10.1176/appi.ajp.2013.12111460
    • Jackson GS, Burk-Rafel J, Edgeworth JA, Sicilia A, Abdilahi S, Korteweg J, Mackey J, Thomas C, Wang G, Schott JM, Mummery C, Chinnery PF, Mead S, Collinge J (2014). Population Screening for Variant Creutzfeldt-Jakob Disease Using a Novel Blood Test: Diagnostic Accuracy and Feasibility Study.. JAMA Neurol, , - . doi:10.1001/jamaneurol.2013.6001
    • Jackson GS, Burk-Rafel J, Edgeworth JA, Sicilia A, Abdilahi S, Korteweg J, Mackey J, Thomas C, Wang G, Mead S, Collinge J (2014). A highly specific blood test for vCJD.. Blood, 123(3), 452 - 453. doi:10.1182/blood-2013-11-539239
    • Beck J, Adamson G, Campbell T, Uphill J, Poulter M, Collinge J, Mead S, Pittman A, Houlden H, Shoai M, Hardy J, Kenny J, Rohrer JD, Mummery CJ, Warren JD, Schott JM, Fox NC, Rossor MN, de Silva R (2014). Validation of next-generation sequencing technologies in genetic diagnosis of dementia. Neurobiology of Aging, 35(1), 261 - 265. doi:10.1016/j.neurobiolaging.2013.07.017
    • Hu NW, Nicoll AJ, Zhang D, Mably AJ, O'Malley T, Purro SA, Terry C, Collinge J, Walsh DM, Rowan MJ (2014). mGlu5 receptors and cellular prion protein mediate amyloid-β-facilitated synaptic long-term depression in vivo.. Nat Commun, 5, 3374 - . doi:10.1038/ncomms4374
    • Mead S, Wadsworth JD, Porter MC, Linehan JM, Pietkiewicz W, Jackson GS, Brandner S, Collinge J (2014). Variant Creutzfeldt-Jakob Disease With Extremely Low Lymphoreticular Deposition of Prion Protein.. JAMA Neurol, , - . doi:10.1001/jamaneurol.2013.5378

    2013

    • Jackson GS, D-GEN LTD, Collinge J, Edgeworth JA (2013). Assay for Prions.
    • Akhtar S, Grizenkova J, Wenborn A, Hummerich H, Fernandez de Marco M, Brandner S, Collinge J, Lloyd SE (2013). Sod1 deficiency reduces incubation time in mouse models of prion disease.. PLoS One, 8(1), e54454 - . doi:10.1371/journal.pone.0054454
    • Reiniger L, Mirabile I, Lukic A, Wadsworth JD, Linehan JM, Groves M, Lowe J, Druyeh R, Rudge P, Collinge J, Mead S, Brandner S (2013). Filamentous white matter prion protein deposition is a distinctive feature of multiple inherited prion diseases.. Acta Neuropathol Commun, 1(1), 8 - . doi:10.1186/2051-5960-1-8
    • Wadsworth JD, Joiner S, Linehan JM, Balkema-Buschmann A, Spiropoulos J, Simmons MM, Griffiths PC, Groschup MH, Hope J, Brandner S, Asante EA, Collinge J (2013). Atypical scrapie prions from sheep and lack of disease in transgenic mice overexpressing human prion protein.. Emerg Infect Dis, 19(11), 1731 - 1739. doi:10.3201/eid1911.121341
    • Mead S, Gandhi S, Beck J, Caine D, Gallujipali D, Carswell C, Hyare H, Joiner S, Ayling H, Lashley T, Linehan JM, Al-Doujaily H, Sharps B, Revesz T, Sandberg M, Reilly M, Koltzenburg M, Forbes A, Rudge P, Brandner S, Warren JD, Wadsworth JDF, Wood NW, Holton JL, Collinge J (2013). A Novel Prion Disease Presenting with Diarrhea and Autonomic Neuropathy. New England Journal of Medicine, , - .
    • Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, Jun G, Destefano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thornton-Wells TA, Jones N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Gerrish A, Schmidt H, Kunkle B, Dunstan ML, Ruiz A, Bihoreau MT, Choi SH, Reitz C, Pasquier F, Hollingworth P, Ramirez A, Hanon O, Fitzpatrick AL, Buxbaum JD, Campion D, Crane PK, Baldwin C, Becker T, Gudnason V, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, Morón FJ, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, Fiévet N, Huentelman MJ, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuinness B, Larson EB, Green R, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, St George-Hyslop P, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, Bossù P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Sanchez-Garcia F, Fox NC, Hardy J, Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Mancuso M, Matthews F, European Alzheimer's Disease Initiative (EADI) , Genetic and Environmental Risk in Alzheimer's Disease (GERAD) , Alzheimer's Disease Genetic Consortium (ADGC) , Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) , Moebus S, Mecocci P, Del Zompo M, Maier W, Hampel H, Pilotto A, Bullido M, Panza F, Caffarra P, Nacmias B, Gilbert JR, Mayhaus M, Lannfelt L, Hakonarson H, Pichler S, Carrasquillo MM, Ingelsson M, Beekly D, Alvarez V, Zou F, Valladares O, Younkin SG, Coto E, Hamilton-Nelson KL, Gu W, Razquin C, Pastor P, Mateo I, Owen MJ, Faber KM, Jonsson PV, Combarros O, O'Donovan MC, Cantwell LB, Soininen H, Blacker D, Mead S, Mosley TH, Bennett DA, Harris TB, Fratiglioni L, Holmes C, de Bruijn RF, Passmore P, Montine TJ, Bettens K, Rotter JI, Brice A, Morgan K, Foroud TM, Kukull WA, Hannequin D, Powell JF, Nalls MA, Ritchie K, Lunetta KL, Kauwe JS, Boerwinkle E, Riemenschneider M, Boada M, Hiltunen M, Martin ER, Schmidt R, Rujescu D, Wang LS, Dartigues JF, Mayeux R, Tzourio C, Hofman A, Nöthen MM, Graff C, Psaty BM, Jones L, Haines JL, Holmans PA, Lathrop M, Pericak-Vance MA, Launer LJ, Farrer LA, van Duijn CM, Van Broeckhoven C, Moskvina V, Seshadri S, Williams J, Schellenberg GD, Amouyel P (2013). Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.. Nat Genet, , - . doi:10.1038/ng.2802
    • Asante EA, Linehan JM, Smidak M, Tomlinson A, Grimshaw A, Jeelani A, Jakubcova T, Hamdan S, Powell C, Brandner S, Wadsworth JD, Collinge J (2013). Inherited Prion Disease A117V Is Not Simply a Proteinopathy but Produces Prions Transmissible to Transgenic Mice Expressing Homologous Prion Protein.. PLoS Pathog, 9(9), e1003643 - . doi:10.1371/journal.ppat.1003643
    • Nicoll AJ, Panico S, Freir DB, Wright D, Terry C, Risse E, Herron CE, O'Malley T, Wadsworth JD, Farrow MA, Walsh DM, Saibil HR, Collinge J (2013). Amyloid-β nanotubes are associated with prion protein-dependent synaptotoxicity.. Nat Commun, 4, 2416 - . doi:10.1038/ncomms3416
    • Goold R, McKinnon C, Rabbanian S, Collinge J, Schiavo G, Tabrizi SJ (2013). Alternative fates of newly formed PrPSc upon prion conversion on the plasma membrane. JOURNAL OF CELL SCIENCE, 126(16), 3552 - 3562. doi:10.1242/jcs.120477
    • Fratta P, Poulter M, Lashley T, Rohrer JD, Polke JM, Beck J, Ryan N, Hensman D, Mizielinska S, Waite AJ, Lai MC, Gendron TF, Petrucelli L, Fisher EM, Revesz T, Warren JD, Collinge J, Isaacs AM, Mead S (2013). Homozygosity for the C9orf72 GGGGCC repeat expansion in frontotemporal dementia.. Acta Neuropathol, , - . doi:10.1007/s00401-013-1147-0
    • Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Williams A, Jones N, Thomas C, Stretton A, Morgan AR, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Morgan K, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Holmes C, Mann D, Smith AD, Love S, Kehoe PG, Hardy J, Mead S, Fox N, Rossor M, Collinge J, Maier W, Jessen F, Schürmann B, Heun R, van den Bussche H, Heuser I, Kornhuber J, Wiltfang J, Dichgans M, Frölich L, Hampel H, Hüll M, Rujescu D, Goate AM, Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Sleegers K, Bettens K, Engelborghs S, De Deyn PP, Van Broeckhoven C, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Tsolaki M, Singleton AB, Guerreiro R, Mühleisen TW, Nöthen MM, Moebus S, Jöckel KH, Klopp N, Wichmann HE, Carrasquillo MM, Pankratz VS, Younkin SG, Holmans PA, O'Donovan M, Owen MJ, Williams J (2013). Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.. Nat Genet, 45(6), 712 - . doi:10.1038/ng0613-712a
    • Reiniger L, Mirabile I, Lukic A, Linehan J, Groves M, Rudge P, Collinge J, Mead S, Brandner S (2013). Filamentous white matter prion protein deposition is a distinctive feature of multiple inherited prion diseases.
    • De Vita E, Ridgway GR, Scahill RI, Caine D, Rudge P, Yousry TA, Mead S, Collinge J, Jäger HR, Thornton JS, Hyare H (2013). Multiparameter MR imaging in the 6-OPRI variant of inherited prion disease.. AJNR Am J Neuroradiol, 34(9), 1723 - 1730. doi:10.3174/ajnr.A3504
    • Beck J, Poulter M, Hensman D, Rohrer JD, Mahoney CJ, Adamson G, Campbell T, Uphill J, Borg A, Fratta P, Orrell RW, Malaspina A, Rowe J, Brown J, Hodges J, Sidle K, Polke JM, Houlden H, Schott JM, Fox NC, Rossor MN, Tabrizi SJ, Isaacs AM, Hardy J, Warren JD, Collinge J, Mead S (2013). Large C9orf72 hexanucleotide repeat expansions are seen in multiple neurodegenerative syndromes and are more frequent than expected in the UK population.. Am J Hum Genet, 92(3), 345 - 353. doi:10.1016/j.ajhg.2013.01.011
    • Guerreiro R, Wojtas A, Bras J, Carrasquillo M, Rogaeva E, Majounie E, Cruchaga C, Sassi C, Kauwe JS, Younkin S, Hazrati L, Collinge J, Pocock J, Lashley T, Williams J, Lambert JC, Amouyel P, Goate A, Rademakers R, Morgan K, Powell J, St George-Hyslop P, Singleton A, Hardy J, Alzheimer Genetic Analysis G (2013). TREM2 variants in Alzheimer's disease. N Engl J Med, 368, 117 - 127. doi:10.1056/NEJMoa1211851
    • Guerreiro R, Wojtas A, Bras J, Carrasquillo M, Rogaeva E, Majounie E, Cruchaga C, Sassi C, Kauwe JS, Younkin S, Hazrati L, Collinge J, Pocock J, Lashley T, Williams J, Lambert JC, Amouyel P, Goate A, Rademakers R, Morgan K, Powell J, St George-Hyslop P, Singleton A, Hardy J, Alzheimer Genetic Analysis Group (2013). TREM2 variants in Alzheimer's disease.. N Engl J Med, 368(2), 117 - 127. doi:10.1056/NEJMoa1211851
    • Klöhn PC, Castro-Seoane R, Collinge J (2013). Exosome release from infected dendritic cells: A clue for a fast spread of prions in the periphery?. J Infect, , - . doi:10.1016/j.jinf.2013.07.024
    • Angus-Leppan H, Rudge P, Mead S, Collinge J, Vincent A (2013). Autoantibodies in Sporadic Creutzfeldt-Jakob Disease.. JAMA Neurol, , 1 - 4. doi:10.1001/jamaneurol.2013.2077
    • Thompson AG, Lowe J, Fox Z, Lukic A, Porter MC, Ford L, Gorham M, Gopalakrishnan GS, Rudge P, Walker AS, Collinge J, Mead S (2013). The Medical Research Council prion disease rating scale: a new outcome measure for prion disease therapeutic trials developed and validated using systematic observational studies.. Brain, 136(Pt 4), 1116 - 1127. doi:10.1093/brain/awt048
    • Lloyd SE, Mead S, Collinge J (2013). Genetics of prion diseases.. Curr Opin Genet Dev, 23(3), 345 - 351. doi:10.1016/j.gde.2013.02.012
    • Angus-Leppan H, Rudge P, Mead S, Collinge J, Vincent A (2013). Creutzfeld-jakob disease-reply.. JAMA Neurol, 70(12), 1589 - . doi:10.1001/jamaneurol.2013.4777

    2012

    • Carswell C, Thompson A, Lukic A, Stevens J, Rudge P, Mead S, Collinge J, Hyare H (2012). MRI findings are often missed in the diagnosis of Creutzfeldt-Jakob disease.. BMC Neurol, 12, 153 - . doi:10.1186/1471-2377-12-153
    • Porter MC, Hyare H, De Vita E, Thompson A, Lukic A, Yousry T, Rudge P, Mead S, Collinge J, Thornton J (2012). VOXELWISE ANALYSIS OF CEREBRAL DIFFUSION TENSOR IMAGING IN PRION DISEASES. doi:10.1136/jnnp-2011-301993.64
    • Kloehn P, Castro-Seoane R, Hummerich H, Sweeting T, Tattum H, Linehan J, de Marco MF, Brandner S, Collinge J (2012). Plasmacytoid dendritic cells sequester high prion titers at early stages of prion infection. PRION, 6, 7 - 7.
    • Quarterman E, Pannell M, Adams N, Farrow M, Collinge J (2012). High throughput screen of pharmacologically active compounds using chronically infected neuroblastoma (PK1) cells. PRION, 6, 102 - 102.
    • Hyare H, Ramlackhansingh A, Gelosa G, Edison P, Rudge P, Brandner S, Brooks DJ, Collinge J, Mead S (2012). C-11-PiB PET does not detect PrP-amyloid in prion disease patients including variant Creutzfeldt-Jakob disease. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 83(3), 340 - 341.
    • Ghazi-Noori S, Froud KE, Mizielinska S, Powell C, Smidak M, Fernandez de Marco M, O'Malley C, Farmer M, Parkinson N, Fisher EM, Asante EA, Brandner S, Collinge J, Isaacs AM (2012). Progressive neuronal inclusion formation and axonal degeneration in CHMP2B mutant transgenic mice.. Brain, 135(Pt 3), 819 - 832. doi:10.1093/brain/aws006
    • Mahoney CJ, Beck J, Rohrer JD, Lashley T, Mok K, Shakespeare T, Yeatman T, Warrington EK, Schott JM, Fox NC, Rossor MN, Hardy J, Collinge J, Revesz T, Mead S, Warren JD (2012). Frontotemporal dementia with the C9ORF72 hexanucleotide repeat expansion: clinical, neuroanatomical and neuropathological features.. Brain, 135(Pt 3), 736 - 750. doi:10.1093/brain/awr361
    • Castro-Seoane R, Hummerich H, Sweeting T, Tattum MH, Linehan JM, Fernandez de Marco M, Brandner S, Collinge J, Klöhn PC (2012). Plasmacytoid dendritic cells sequester high prion titres at early stages of prion infection.. PLoS Pathog, 8(2), e1002538 - . doi:10.1371/journal.ppat.1002538
    • Collinge J (2012). Cell biology. The risk of prion zoonoses.. Science, 335(6067), 411 - 413. doi:10.1126/science.1218167
    • Klöhn PC, Farmer M, Linehan JM, O'Malley C, Fernandez de Marco M, Taylor W, Farrow M, Khalili-Shirazi A, Brandner S, Collinge J (2012). PrP antibodies do not trigger mouse hippocampal neuron apoptosis.. Science, 335(6064), 52 - . doi:10.1126/science.1215579
    • Mead S, Uphill J, Beck J, Poulter M, Campbell T, Lowe J, Adamson G, Hummerich H, Klopp N, Rückert IM, Wichmann HE, Azazi D, Plagnol V, Pako WH, Whitfield J, Alpers MP, Whittaker J, Balding DJ, Zerr I, Kretzschmar H, Collinge J (2012). Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP.. Hum Mol Genet, 21(8), 1897 - 1906. doi:10.1093/hmg/ddr607
    • Beck J, Collinge J, Mead S (2012). Prion protein gene M232R variation is probably an uncommon polymorphism rather than a pathogenic mutation.. Brain, 135(Pt 2), e209 - . doi:10.1093/brain/awr294
    • Gerrish A, Russo G, Richards A, Moskvina V, Ivanov D, Harold D, Sims R, Abraham R, Hollingworth P, Chapman J, Hamshere M, Pahwa JS, Dowzell K, Williams A, Jones N, Thomas C, Stretton A, Morgan AR, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Morgan K, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Johnston JA, Holmes C, Mann D, Smith AD, Love S, Kehoe PG, Hardy J, Mead S, Fox N, Rossor M, Collinge J, Maier W, Jessen F, Kölsch H, Heun R, Schürmann B, van den Bussche H, Heuser I, Kornhuber J, Wiltfang J, Dichgans M, Frölich L, Hampel H, Hüll M, Rujescu D, Goate AM, Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Davies G, Harris SE, Starr JM, Deary IJ, Al-Chalabi A, Shaw CE, Tsolaki M, Singleton AB, Guerreiro R, Mühleisen TW, Nöthen MM, Moebus S, Jöckel KH, Klopp N, Wichmann HE, Carrasquillo MM, Pankratz VS, Younkin SG, Jones L, Holmans PA, O'Donovan MC, Owen MJ, Williams J (2012). The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease.. J Alzheimers Dis, 28(2), 377 - 387. doi:10.3233/JAD-2011-110824
    • Alner K, Hyare H, Mead S, Rudge P, Wroe S, Rohrer JD, Ridgway GR, Ourselin S, Clarkson M, Hunt H, Fox NC, Webb T, Collinge J, Cipolotti L (2012). Distinct neuropsychological profiles correspond to distribution of cortical thinning in inherited prion disease caused by insertional mutation.. J Neurol Neurosurg Psychiatry, 83(1), 109 - 114. doi:10.1136/jnnp-2011-300167
    • Hyare H, Ramlackhansingh A, Gelosa G, Edison P, Rudge P, Brandner S, Brooks DJ, Collinge J, Mead S (2012). 11C-PiB PET does not detect PrP-amyloid in prion disease patients including variant Creutzfeldt-Jakob disease.. J Neurol Neurosurg Psychiatry, 83(3), 340 - 341. doi:10.1136/jnnp.2010.233692
    • McNaughton D, Knight W, Guerreiro R, Ryan N, Lowe J, Poulter M, Nicholl DJ, Hardy J, Revesz T, Lowe J, Rossor M, Collinge J, Mead S (2012). Duplication of amyloid precursor protein (APP), but not prion protein (PRNP) gene is a significant cause of early onset dementia in a large UK series.. Neurobiol Aging, 33(2), 426.e13 - 426.e21. doi:10.1016/j.neurobiolaging.2010.10.010
    • Grizenkova J, Akhtar S, Hummerich H, Tomlinson A, Asante EA, Wenborn A, Fizet J, Poulter M, Wiseman FK, Fisher EM, Tybulewicz VL, Brandner S, Collinge J, Lloyd SE (2012). Overexpression of the Hspa13 (Stch) gene reduces prion disease incubation time in mice.. Proc Natl Acad Sci U S A, 109(34), 13722 - 13727. doi:10.1073/pnas.1208917109
    • Carswell C, Rañopa M, Pal S, Macfarlane R, Siddique D, Thomas D, Webb T, Wroe S, Walker S, Darbyshire J, Collinge J, Mead S, Rudge P (2012). Video Rating in Neurodegenerative Disease Clinical Trials: The Experience of PRION-1.. Dement Geriatr Cogn Dis Extra, 2(1), 286 - 297.
    • Collinge J (2012). Prion propagation and its wider implications. PRION, 6, 1 - 1.
    • Mead S, Beck J, Poulter M, Rohrer J, Adamson G, Hensman D, Polke J, Campbell T, Uphill J, Borg A, Tabrizi S, Isaacs A, Hardy J, Warren J, Collinge J (2012). Large C9ORF72 hexanucleotide expansions arise spontaneously in the healthy population but can be distinguished from pathogenic mutations by Sothern Blotting.

    2011

    • Begum R, Lloyd S, Collinge J (2011). Functional analysis of a prion disease modifier linked to incubation time.
    • Rollinson S, Rohrer JD, van der Zee J, Sleegers K, Mead S, Engelborghs S, Collinge J, De Deyn PP, Mann DM, Van Broeckhoven C, Pickering-Brown SM (2011). No association of PGRN 3'UTR rs5848 in frontotemporal lobar degeneration.. Neurobiol Aging, 32(4), 754 - 755. doi:10.1016/j.neurobiolaging.2009.04.009
    • Sims R, Dwyer S, Harold D, Gerrish A, Hollingworth P, Chapman J, Jones N, Abraham R, Ivanov D, Pahwa JS, Moskvina V, Dowzell K, Thomas C, Stretton A, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Morgan K, Brown KS, Passmore PA, Craig D, McGuiness B, Todd S, Johnston JA, Holmes C, Mann D, Smith AD, Love S, Kehoe PG, Hardy J, Mead S, Fox N, Rossor M, Collinge J, Livingston G, Bass NJ, Gurling H, McQuillin A, Jones L, Holmans PA, O'Donovan M, Owen MJ, Williams J (2011). No evidence that extended tracts of homozygosity are associated with Alzheimer's disease.. Am J Med Genet B Neuropsychiatr Genet, 156B(7), 764 - 771. doi:10.1002/ajmg.b.31216
    • Carswell C, Drynda R, Martins S, Clarke A, Brandner S, Mead S, Collinge J, Khalili-Shirazi A (2011). PAW35 Anti-prion protein monoclonal antibodies at low doses effectively treat prion disease in mice without side-effects (vol 81, pg e33, 2010). J NEUROL NEUROSUR PS, 82(7), 826 - 826. doi:10.1136/jnnp.2010.226340.63corr1
    • Kaski DN, Pennington C, Beck J, Poulter M, Uphill J, Bishop MT, Linehan JM, O'Malley C, Wadsworth JD, Joiner S, Knight RS, Ironside JW, Brandner S, Collinge J, Mead S (2011). Inherited prion disease with 4-octapeptide repeat insertion: disease requires the interaction of multiple genetic risk factors.. Brain, 134(Pt 6), 1829 - 1838. doi:10.1093/brain/awr079
    • Hollingworth P, Harold D, Sims R, Gerrish A, Lambert JC, Carrasquillo MM, Abraham R, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Jones N, Stretton A, Thomas C, Richards A, Ivanov D, Widdowson C, Chapman J, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Holmes C, Mann D, Smith AD, Beaumont H, Warden D, Wilcock G, Love S, Kehoe PG, Hooper NM, Vardy ER, Hardy J, Mead S, Fox NC, Rossor M, Collinge J, Maier W, Jessen F, Rüther E, Schürmann B, Heun R, Kölsch H, van den Bussche H, Heuser I, Kornhuber J, Wiltfang J, Dichgans M, Frölich L, Hampel H, Gallacher J, Hüll M, Rujescu D, Giegling I, Goate AM, Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Sleegers K, Bettens K, Engelborghs S, De Deyn PP, Van Broeckhoven C, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Tsolaki M, Singleton AB, Guerreiro R, Mühleisen TW, Nöthen MM, Moebus S, Jöckel KH, Klopp N, Wichmann HE, Pankratz VS, Sando SB, Aasly JO, Barcikowska M, Wszolek ZK, Dickson DW, Graff-Radford NR, Petersen RC, Alzheimer's Disease Neuroimaging Initiative , van Duijn CM, Breteler MM, Ikram MA, DeStefano AL, Fitzpatrick AL, Lopez O, Launer LJ, Seshadri S, CHARGE consortium , Berr C, Campion D, Epelbaum J, Dartigues JF, Tzourio C, Alpérovitch A, Lathrop M, EADI1 consortium , Feulner TM, Friedrich P, Riehle C, Krawczak M, Schreiber S, Mayhaus M, Nicolhaus S, Wagenpfeil S, Steinberg S, Stefansson H, Stefansson K, Snaedal J, Björnsson S, Jonsson PV, Chouraki V, Genier-Boley B, Hiltunen M, Soininen H, Combarros O, Zelenika D, Delepine M, Bullido MJ, Pasquier F, Mateo I, Frank-Garcia A, Porcellini E, Hanon O, Coto E, Alvarez V, Bosco P, Siciliano G, Mancuso M, Panza F, Solfrizzi V, Nacmias B, Sorbi S, Bossù P, Piccardi P, Arosio B, Annoni G, Seripa D, Pilotto A, Scarpini E, Galimberti D, Brice A, Hannequin D, Licastro F, Jones L, Holmans PA, Jonsson T, Riemenschneider M, Morgan K, Younkin SG, Owen MJ, O'Donovan M, Amouyel P, Williams J (2011). Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.. Nat Genet, 43(5), 429 - 435. doi:10.1038/ng.803
    • Rohrer JD, Warren JD, Reiman D, Uphill J, Beck J, Collinge J, Rossor MN, Isaacs AM, Mead S (2011). A novel exon 2 I27V VCP variant is associated with dissimilar clinical syndromes.. J Neurol, 258(8), 1494 - 1496. doi:10.1007/s00415-011-5966-4
    • Wadsworth JD, Dalmau-Mena I, Joiner S, Linehan JM, O'Malley C, Powell C, Brandner S, Asante EA, Ironside JW, Hilton DA, Collinge J (2011). Effect of fixation on brain and lymphoreticular vCJD prions and bioassay of key positive specimens from a retrospective vCJD prevalence study.. J Pathol, 223(4), 511 - 518. doi:10.1002/path.2821
    • Sandberg MK, Al-Doujaily H, Sharps B, Clarke AR, Collinge J (2011). Prion propagation and toxicity in vivo occur in two distinct mechanistic phases.. Nature, 470(7335), 540 - 542. doi:10.1038/nature09768
    • Edgeworth JA, Farmer M, Sicilia A, Tavares P, Beck J, Campbell T, Lowe J, Mead S, Rudge P, Collinge J, Jackson GS (2011). Detection of prion infection in variant Creutzfeldt-Jakob disease: a blood-based assay.. Lancet, 377(9764), 487 - 493. doi:10.1016/S0140-6736(10)62308-2
    • Ratté S, Vreugdenhil M, Boult JK, Patel A, Asante EA, Collinge J, Jefferys JG (2011). Threshold for epileptiform activity is elevated in prion knockout mice.. Neuroscience, 179, 56 - 61. doi:10.1016/j.neuroscience.2011.01.053
    • Wadsworth JDF, Collinge J (2011). Molecular pathology of human prion disease. ACTA NEUROPATHOL, 121(1), 69 - 77. doi:10.1007/s00401-010-0735-5
    • Reiniger L, Lukic A, Linehan J, Rudge P, Collinge J, Mead S, Brandner S (2011). Prion protein-induced tau phosphorylation: insight into a universal mechanism triggered by cerebral amyloid.
    • Jones L, Holmans PA, Hamshere ML, Harold D, Moskvina V, Ivanov D, Pocklington A, Abraham R, Hollingworth P, Sims R, Gerrish A, Pahwa JS, Jones N, Stretton A, Morgan AR, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Morgan K, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Holmes C, Mann D, Smith AD, Love S, Kehoe PG, Mead S, Fox N, Rossor M, Collinge J, Maier W, Jessen F, Schürmann B, van den Bussche H, Heuser I, Peters O, Kornhuber J, Wiltfang J, Dichgans M, Frölich L, Hampel H, Hüll M, Rujescu D, Goate AM, Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Singleton AB, Guerreiro R, Mühleisen TW, Nöthen MM, Moebus S, Jöckel KH, Klopp N, Wichmann HE, Rüther E, Carrasquillo MM, Pankratz VS, Younkin SG, Hardy J, O'Donovan MC, Owen MJ, Williams J (2011). Correction: genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease.. PLoS One, 6(2), - . doi:10.1371/annotation/a0bb886d-d345-4a20-a82e-adce9b047798
    • Goold R, Rabbanian S, Sutton L, Andre R, Arora P, Moonga J, Clarke AR, Schiavo G, Jat P, Collinge J, Tabrizi SJ (2011). Rapid cell-surface prion protein conversion revealed using a novel cell system. NAT COMMUN, 2, - . doi:10.1038/ncomms1282
    • Edgeworth JA, Sicilia A, Linehan J, Brandner S, Jackson GS, Collinge J (2011). A standardized comparison of commercially available prion decontamination reagents using the Standard Steel-Binding Assay.. J Gen Virol, 92(Pt 3), 718 - 726. doi:10.1099/vir.0.027201-0
    • Stevens JC, Beck J, Lukic A, Ryan N, Abbs S, Collinge J, Fox NC, Mead S (2011). Familial Alzheimer's disease and inherited prion disease in the UK are poorly ascertained.. J Neurol Neurosurg Psychiatry, 82(9), 1054 - 1057. doi:10.1136/jnnp.2009.199653
    • Reiniger L, Lukic A, Linehan J, Rudge P, Collinge J, Mead S, Brandner S (2011). Tau, prions and Aβ: the triad of neurodegeneration.. Acta Neuropathol, 121(1), 5 - 20. doi:10.1007/s00401-010-0691-0
    • Mead S, Ranopa M, Gopalakrishnan GS, Thompson AG, Rudge P, Wroe S, Kennedy A, Hudson F, MacKay A, Darbyshire JH, Collinge J, Walker AS (2011). PRION-1 scales analysis supports use of functional outcome measures in prion disease.. Neurology, 77(18), 1674 - 1683. doi:10.1212/WNL.0b013e3182364890
    • Deriziotis P, André R, Smith DM, Goold R, Kinghorn KJ, Kristiansen M, Nathan JA, Rosenzweig R, Krutauz D, Glickman MH, Collinge J, Goldberg AL, Tabrizi SJ (2011). Misfolded PrP impairs the UPS by interaction with the 20S proteasome and inhibition of substrate entry.. EMBO J, 30(15), 3065 - 3077. doi:10.1038/emboj.2011.224
    • Freir DB, Nicoll AJ, Klyubin I, Panico S, Mc Donald JM, Risse E, Asante EA, Farrow MA, Sessions RB, Saibil HR, Clarke AR, Rowan MJ, Walsh DM, Collinge J (2011). Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites.. Nat Commun, 2, 336 - . doi:10.1038/ncomms1341
    • Lloyd S, Mead S, Collinge J (2011). Genetics of prion disease.. Top Curr Chem, 305, 1 - 22. doi:10.1007/128_2011_157
    • Lukic A, Mead S, Rudge P, Collinge J (2011). Comment on validation of diagnostic criteria for variant Creutzfeldt-Jakob disease.. Ann Neurol, 69(1), 212 - . doi:10.1002/ana.22273
    • Akhtar S, Wenborn A, Brandner S, Collinge J, Lloyd SE (2011). Sex effects in mouse prion disease incubation time.. PLoS One, 6(12), e28741 - . doi:10.1371/journal.pone.0028741

    2010

    • Wadsworth JD, Dalmau-Mena I, Joiner S, Linehan JM, O'Malley C, Powell C, Brandner S, Asante EA, Ironside JW, Hilton DA, Collinge J (2010). Effect of fixation on brain and lymphoreticular vCJD prions and bioassay of key positive specimens from a retrospective vCJD prevalence study.. J Pathol, , - . doi:10.1002/path.2821
    • Grizenkova J, Akhtar S, Collinge J, Lloyd SE (2010). The retinoic acid receptor beta (Rarb) region of Mmu14 is associated with prion disease incubation time in mouse.. PLoS One, 5(12), e15019 - . doi:10.1371/journal.pone.0015019
    • Carswell C, Khalili-Shirazi A, Brandner S, Martins S, Drynda R, Collinge J, Mead S, Clarke A (2010). PAW35 Anti-prion protein monoclonal antibodies at low doses effectively treat prion disease in mice without side-effects.. J Neurol Neurosurg Psychiatry, 81(11), e33 - . doi:10.1136/jnnp.2010.226340.63
    • Lukic A, Wadsworth J, Brandner S, Rudge P, Hyare H, Collinge J, Reiniger L, Mead S, Gilmore C, Humberstone M (2010). POD01 Misleading MRI in two recent patients with variant Creutzfeldt-Jakob disease emphasises the importance of tissue diagnosis.. J Neurol Neurosurg Psychiatry, 81(11), e42 - . doi:10.1136/jnnp.2010.226340.101
    • Siddique D, Hyare H, Wroe S, Webb T, Macfarlane R, Rudge P, Collinge J, Powell C, Brandner S, So PW, Walker S, Mead S, Yousry T, Thornton JS (2010). Magnetization transfer ratio may be a surrogate of spongiform change in human prion diseases.. Brain, 133(10), 3058 - 3068. doi:10.1093/brain/awq243
    • Wadsworth JD, Asante EA, Collinge J (2010). Review: contribution of transgenic models to understanding human prion disease.. Neuropathol Appl Neurobiol, 36(7), 576 - 597. doi:10.1111/j.1365-2990.2010.01129.x
    • Lukic A, Beck J, Joiner S, Fearnley J, Sturman S, Brandner S, Wadsworth JD, Collinge J, Mead S (2010). Heterozygosity at polymorphic codon 219 in variant creutzfeldt-jakob disease.. Arch Neurol, 67(8), 1021 - 1023. doi:10.1001/archneurol.2010.184
    • Edgeworth JA, Gros N, Alden J, Joiner S, Wadsworth JD, Linehan J, Brandner S, Jackson GS, Weissmann C, Collinge J (2010). Spontaneous generation of mammalian prions.. Proc Natl Acad Sci U S A, 107(32), 14402 - 14406. doi:10.1073/pnas.1004036107
    • Sandberg MK, Al-Doujaily H, Sigurdson CJ, Glatzel M, O'Malley C, Powell C, Asante EA, Linehan JM, Brandner S, Wadsworth JD, Collinge J (2010). Chronic wasting disease prions are not transmissible to transgenic mice overexpressing human prion protein.. J Gen Virol, 91(Pt 10), 2651 - 2657. doi:10.1099/vir.0.024380-0
    • Nicoll AJ, Trevitt CR, Tattum MH, Risse E, Quaterman E, Ibarra AA, Jackson GS, Sessions RB, Farrow M, Waltho JP, Clarke AR, Collinge J (2010). A pharmacological chaperone for the structured domain of human prion protein. PRION, 4(3), 130 - 130.
    • Asante EA, Linehan JM, Smidak M, Brandner S, Collinge J (2010). Inherited prion disease A117V is transmissible to transgenic mice expressing PRNP 117-valine. PRION, 4(3), 156 - 156.
    • Mead S, Thompson A, Gopalakrishnan G, Ranopa M, Rudge P, Wroe S, Hudson F, MacKay A, Darbyshire J, Collinge J, Walker S (2010). Analysis of Eight Rating Scales Supports the use of Functional Outcome Measures in Prion Disease Clinical Trials: Experience from the PRION-1 trial and the National Prion Monitoring Cohort.
    • Urwin H, Josephs KA, Rohrer JD, Mackenzie IR, Neumann M, Authier A, Seelaar H, Van Swieten JC, Brown JM, Johannsen P, Nielsen JE, Holm IE, FReJA Consortium , Dickson DW, Rademakers R, Graff-Radford NR, Parisi JE, Petersen RC, Hatanpaa KJ, White CL, Weiner MF, Geser F, Van Deerlin VM, Trojanowski JQ, Miller BL, Seeley WW, van der Zee J, Kumar-Singh S, Engelborghs S, De Deyn PP, Van Broeckhoven C, Bigio EH, Deng HX, Halliday GM, Kril JJ, Munoz DG, Mann DM, Pickering-Brown SM, Doodeman V, Adamson G, Ghazi-Noori S, Fisher EM, Holton JL, Revesz T, Rossor MN, Collinge J, Mead S, Isaacs AM (2010). FUS pathology defines the majority of tau- and TDP-43-negative frontotemporal lobar degeneration.. Acta Neuropathol, 120(1), 33 - 41. doi:10.1007/s00401-010-0698-6
    • Mead S, Hyare H, Collinge J, Rudge P (2010). Variant or sporadic Creutzfeldt-Jakob disease? reply. LANCET, 375(9718), 889 - 890.
    • Urwin H, Authier A, Nielsen JE, Metcalf D, Powell C, Froud K, Malcolm DS, Holm I, Johannsen P, Brown J, Fisher EM, van der Zee J, Bruyland M, FReJA Consortium , Van Broeckhoven C, Collinge J, Brandner S, Futter C, Isaacs AM (2010). Disruption of endocytic trafficking in frontotemporal dementia with CHMP2B mutations.. Hum Mol Genet, 19(11), 2228 - 2238. doi:10.1093/hmg/ddq100
    • Hyare H, Wroe S, Siddique D, Webb T, Fox NC, Stevens J, Collinge J, Yousry T, Thornton JS (2010). Brain-water diffusion coefficients reflect the severity of inherited prion disease. NEUROLOGY, 74(8), 658 - 665.
    • Guerreiro RJ, Beck J, Gibbs JR, Santana I, Rossor MN, Schott JM, Nalls MA, Ribeiro H, Santiago B, Fox NC, Oliveira C, Collinge J, Mead S, Singleton A, Hardy J (2010). Genetic variability in CLU and its association with Alzheimer's disease.. PLoS One, 5(3), e9510 - . doi:10.1371/journal.pone.0009510
    • Jones L, Holmans PA, Hamshere ML, Harold D, Moskvina V, Ivanov D, Pocklington A, Abraham R, Hollingworth P, Sims R, Gerrish A, Pahwa JS, Jones N, Stretton A, Morgan AR, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Morgan K, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Holmes C, Mann D, Smith AD, Love S, Kehoe PG, Mead S, Fox N, Rossor M, Collinge J, Maier W, Jessen F, Schürmann B, Heun R, Kölsch H, van den Bussche H, Heuser I, Peters O, Kornhuber J, Wiltfang J, Dichgans M, Frölich L, Hampel H, Hüll M, Rujescu D, Goate AM, Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Singleton AB, Guerreiro R, Mühleisen TW, Nöthen MM, Moebus S, Jöckel KH, Klopp N, Wichmann HE, Rüther E, Carrasquillo MM, Pankratz VS, Younkin SG, Hardy J, O'Donovan MC, Owen MJ, Williams J (2010). Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease.. PLoS One, 5(11), e13950 - . doi:10.1371/journal.pone.0013950
    • D'Castro L, Wenborn A, Gros N, Joiner S, Cronier S, Collinge J, Wadsworth JD (2010). Isolation of proteinase K-sensitive prions using pronase E and phosphotungstic acid.. PLoS One, 5(12), e15679 - . doi:10.1371/journal.pone.0015679
    • Hyare H, Thornton J, Stevens J, Mead S, Rudge P, Collinge J, Yousry TA, Jäger HR (2010). High-b-value diffusion MR imaging and basal nuclei apparent diffusion coefficient measurements in variant and sporadic Creutzfeldt-Jakob disease.. AJNR Am J Neuroradiol, 31(3), 521 - 526. doi:10.3174/ajnr.A1860
    • Lloyd SE, Maytham EG, Grizenkova J, Hummerich H, Collinge J (2010). A Copine family member, Cpne8, is a candidate quantitative trait gene for prion disease incubation time in mouse.. Neurogenetics, 11(2), 185 - 191. doi:10.1007/s10048-009-0219-8
    • Hyare H, Scahill R, Thornton JS, Collinge J, Siddique D, Carswell C, De Vita E, Yousry T, Rudge P, Mead S (2010). PAW23 Voxel-based analysis of magnetisation transfer ratio as a potential biomarker in prion diseases.. doi:10.1136/jnnp.2010.226340.52
    • Rudge P, Fox NC, Cipolotti L, Mead S, Hyare H, Rohrer J, Collinge J (2010). POD03 Distinct neuropsychological profiles correspond to distribution of cortical thinning in inherited prion disease caused by insertional mutation.. J Neurol Neurosurg Psychiatry, 81(11), e42 - e43. doi:10.1136/jnnp.2010.226340.103
    • Thompson A, Rudge P, Wroe S, Mead S, Darbyshire J, Mackay A, Ranopa M, Collinge J, Gopalakrishnan G, Walker S (2010). POD04 Analysis of eight rating scales supports the use of functional outcome measures in prion disease clinical trials: experience from the PRION-1 trial and the National Prion Monitoring cohort.. doi:10.1136/jnnp.2010.226340.104
    • O'Nuallain B, Freir DB, Nicoll AJ, Risse E, Ferguson N, Herron CE, Collinge J, Walsh DM (2010). Amyloid beta-protein dimers rapidly form stable synaptotoxic protofibrils.. J Neurosci, 30(43), 14411 - 14419. doi:10.1523/JNEUROSCI.3537-10.2010
    • Nicoll AJ, Trevitt CR, Tattum MH, Risse E, Quarterman E, Ibarra AA, Wright C, Jackson GS, Sessions RB, Farrow M, Waltho JP, Clarke AR, Collinge J (2010). Pharmacological chaperone for the structured domain of human prion protein.. Proc Natl Acad Sci U S A, 107(41), 17610 - 17615. doi:10.1073/pnas.1009062107
    • Hosszu LL, Tattum MH, Jones S, Trevitt CR, Wells MA, Waltho JP, Collinge J, Jackson GS, Clarke AR (2010). The H187R mutation of the human prion protein induces conversion of recombinant prion protein to the PrP(Sc)-like form.. Biochemistry, 49(40), 8729 - 8738. doi:10.1021/bi100572j
    • Beck JA, Poulter M, Campbell TA, Adamson G, Uphill JB, Guerreiro R, Jackson GS, Stevens JC, Manji H, Collinge J, Mead S (2010). PRNP allelic series from 19 years of prion protein gene sequencing at the MRC Prion Unit.. Hum Mutat, 31(7), E1551 - E1563. doi:10.1002/humu.21281
    • Mead S, Gandhi S, Carswell C, Ayling H, Beck J, Caine D, Gallujipali D, Hyare H, Joiner S, Lees AJ, Linehan J, Revesz T, Sandberg M, Wadsworth JDF, Warren JD, Wood NW, Holton JL, Collinge J (2010). Novel truncation mutation of PRNP causes chronic diarrhoea, sensory neuropathy and autonomic failure associated with prion protein deposition in the cerebral blood vessels and small bowel. PRION, 4(3), 201 - 202.
    • Edgeworth JA, Gros N, Alden J, Joiner S, Wadsworth J, Linehan J, Brandner S, Jackson G, Weissmann C, Collinge J (2010). Spontaneous formation of prions in brain tissue. PRION, 4(3), 140 - 140.
    • Castro-Seoane R, Hummerich H, Sweeting T, Sandberg M, Collinge J, Klohn PC (2010). Quantification of Infectious Titres Using a Generalized Linear Model. PRION, 4(3), 219 - 219.
    • Grizenkova J, Akhtar S, Collinge J, Lloyd SE (2010). The Rarb Region of Mmu14 is Associated with Prion Disease Incubation Time. PRION, 4(3), 201 - 201.
    • Tattum MH, Jones S, Pal S, Khalili-Shirazi A, Collinge J, Jackson GS (2010). A highly sensitive immunoassay for the detection of prion-infected material in whole human blood without the use of proteinase K.. Transfusion, 50(12), 2619 - 2627. doi:10.1111/j.1537-2995.2010.02731.x
    • Collinge J (2010). Medicine. Prion strain mutation and selection.. Science, 328(5982), 1111 - 1112. doi:10.1126/science.1190815
    • Tattum MH, Jones S, Pal S, Collinge J, Jackson GS (2010). Discrimination between prion-infected and normal blood samples by protein misfolding cyclic amplification.. Transfusion, 50(5), 996 - 1002. doi:10.1111/j.1537-2995.2010.02595.x
    • Chia R, Tattum MH, Jones S, Collinge J, Fisher EM, Jackson GS (2010). Superoxide dismutase 1 and tgSOD1 mouse spinal cord seed fibrils, suggesting a propagative cell death mechanism in amyotrophic lateral sclerosis.. PLoS One, 5(5), e10627 - . doi:10.1371/journal.pone.0010627
    • Mead S, Linehan J, Beck J, Caine D, Gandhi S, Wadsworth JD, Joiner S, Gallujipali D, Hyare H, Lees A, Holton J, Sandberg M, Revesz T, Carswell C, Warren JD, Collinge J, Wood N (2010). PATU2 Novel truncation mutation of PRNP causes chronic diarrhoea, sensory neuropathy and autonomic failure associated with prion protein deposition in the cerebral blood vessels and small bowel.. J Neurol Neurosurg Psychiatry, 81(11), e24 - . doi:10.1136/jnnp.2010.226340.31

    2009

    • Hart T, Hosszu LLP, Trevitt CR, Jackson GS, Waltho JP, Collinge J, Clarke AR (2009). Folding kinetics of the human prion protein probed by temperature jump. Proceedings of the National Academy of Sciences of the United States of America, 106(14), 5651 - 5656. doi:10.1073/pnas.0811457106
    • Collinge J (2009). Prion disease. In Gelder MG, Lopez-Ibor Jnr JJ, Andreasen NC (Ed.), Oxford textbook of psychiatry (pp. 404 - 415). : Oxford University Press.
    • Mead S, Whitfield J, Poulter M, Shah P, Uphill J, Campbell T, Al-Dujaily H, Hummerich H, Beck J, Mein CA, Verzilli C, Whittaker J, Alpers MP, Collinge J (2009). A novel protective prion protein variant that colocalizes with kuru exposure.. N Engl J Med, 361(21), 2056 - 2065. doi:10.1056/NEJMoa0809716
    • Rohrer JD, Beck J, Warren JD, King A, Al Sarraj S, Holton J, Revesz T, Collinge J, Mead S (2009). Corticobasal syndrome associated with a novel 1048_1049insG progranulin mutation.. J Neurol Neurosurg Psychiatry, 80(11), 1297 - 1298. doi:10.1136/jnnp.2008.169383
    • Lukic A, Beck JA, Wadsworth JDF, Brandner S, Collinge J, Mead S (2009). HETEROZYGOSITY AT POLYMORPHIC CODON 219 IN TWO VARIANT CREUTZFELDT-JAKOB DISEASE PATIENTS. doi:10.1136/jnnp.2009.191759o
    • Kaski D, Pennington C, Beck J, Poulter M, Uphill J, Bishop M, Lineham J, Powell C, Brandner S, Knight R, Collinge J, Mead S (2009). INHERITED PRION DISEASE WITH 4-OCTAPEPTIDE REPEAT INSERTION - A DISEASE THAT REQUIRES THE INTERACTION OF MULTIPLE GENETIC RISK FACTORS. doi:10.1136/jnnp.2009.191759p
    • Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Williams A, Jones N, Thomas C, Stretton A, Morgan AR, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Morgan K, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Holmes C, Mann D, Smith AD, Love S, Kehoe PG, Hardy J, Mead S, Fox N, Rossor M, Collinge J, Maier W, Jessen F, Schürmann B, Heun R, van den Bussche H, Heuser I, Kornhuber J, Wiltfang J, Dichgans M, Frölich L, Hampel H, Hüll M, Rujescu D, Goate AM, Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Sleegers K, Bettens K, Engelborghs S, De Deyn PP, Van Broeckhoven C, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Tsolaki M, Singleton AB, Guerreiro R, Mühleisen TW, Nöthen MM, Moebus S, Jöckel KH, Klopp N, Wichmann HE, Carrasquillo MM, Pankratz VS, Younkin SG, Holmans PA, O'Donovan M, Owen MJ, Williams J (2009). Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.. Nat Genet, 41(10), 1088 - 1093. doi:10.1038/ng.440
    • Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Williams A, Jones N, Thomas C, Stretton A, Morgan AR, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Morgan K, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Holmes C, Mann D, Smith AD, Love S, Kehoe PG, Hardy J, Mead S, Fox N, Rossor M, Collinge J, Maier W, Jessen F, Schurmann B, van den Bussche H, Heuser I, Kornhuber J, Wiltfang J, Dichgans M, Frolich L, Hampel H, Hull M, Rujescu D, Goate AM, Kauwe JSK, Cruchaga C, Nowotny P, Morris JC, Mayo K, Sleegers K, Bettens K, Engelborghs S, De Deyn PP, Van Broeckhoven C, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Tsolaki M, Singleton AB, Guerreiro R, Muhleisen TW, Nothen MM, Moebus S, Jockel KH, Klopp N, Wichmann HE, Carrasquillo MM, Pankratz VS, Younkin SG, Holmans PA, O'Donovan M, Owen MJ, Williams J (2009). Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease (vol 41, pg 1088, 2009). NAT GENET, 41(10), 1156 - 1156. doi:10.1038/ng1009-1156d
    • Webb T, Mead S, Beck J, Uphill J, Pal S, Hampson S, Wadsworth JD, Dalmau Mena I, O'Malley C, Wroe S, Schapira A, Brandner S, Collinge J (2009). Seven year discordance in age at onset in monozygotic twins with inherited prion disease (P102L). Neuropathology and Applied Neurobiology, 35(4), 427 - 432. doi:10.1111/j.1365-2990.2009.01012.x
    • Webb TEF, Whittaker J, Collinge J, Mead S (2009). Age of onset and death in inherited prion disease are heritable. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 150B(4), 496 - 501. doi:10.1002/ajmg.b.30844
    • Collinge J, Gorham M, Hudson F, Kennedy A, Keogh G, Pal S, Rossor M, Rudge P, Siddique D, Spyer M, Thomas D, Walker S, Webb T, Wroe S, Darbyshire J (2009). Safety and efficacy of quinacrine in human prion disease (PRION-1 study): a patient-preference trial. The Lancet Neurology, 8(4), 334 - 344. doi:10.1016/S1474-4422(09)70049-3
    • Rollinson S, Rizzu P, Sikkink S, Baker M, Halliwell N, Snowden J, Traynor BJ, Ruano D, Cairns N, Rohrer JD, Mead S, Collinge J, Rossor M, Akay E, Guerreiro R, Rademakers R, Morrison KE, Pastor P, Alonso E, Martinez-Lage P, Graff-Radford N, Neary D, Heutink P, Mann DMA, Van Swieten J, Pickering-Brown SM (2009). Ubiquitin associated protein 1 is a risk factor for frontotemporal lobar degeneration. Neurobiology of Aging, 30(4), 656 - 665. doi:10.1016/j.neurobiolaging.2009.01.009
    • Siddique D, Wroe S, Hyare H, Webb T, Macfarlane R, Collinge J, Walker S, Yousry T, Thornton JS (2009). A CORRELATION OF GLOBAL AND TISSUE-SPECIFIC CEREBRAL MAGNETISATION TRANSFER RATIOS WITH DISEASE SEVERITY IN INHERITED PRION DISEASE.
    • Asante EA, Gowland I, Grimshaw A, Linehan JM, Smidak M, Houghton R, Osiguwa O, Tomlinson A, Joiner S, Brandner S, Wadsworth JD, Collinge J (2009). Absence of spontaneous disease and comparative prion susceptibility of transgenic mice expressing mutant human prion proteins. Journal of General Virology, 90(3), 546 - 558. doi:10.1099/vir.0.007930-0
    • Edgeworth JA, Jackson GS, Clarke AR, Weissmann C, Collinge J (2009). Highly sensitive, quantitative cell-based assay for prions adsorbed to solid surfaces. Proceedings of the National Academy of Sciences of the United States of America, 106(9), 3479 - 3483. doi:10.1073/pnas.0813342106
    • Urwin H, Ghazi-Noori S, Collinge J, Isaacs A (2009). The role of CHMP2B in frontotemporal dementia. Biochemical Society Transactions, 37(1), 208 - 212. doi:10.1042/BST0370208
    • Rossor M, Collinge J, Fox N, Howard R, Mallucci G, Mummery C, Warren J (2009). Cognitive impairment and dementia. In Clarke C, Howard R, Rossor M, Shorvon S (Ed.), Neurology: a Queen Square textbook (pp. 245 - 288). : Wiley-Blackwell.
    • Collinge J (2009). Prion disease. In Gelder MG, Andreasen NC, Lopez-Ibor JJ, Geddes JR (Ed.), New Oxford Textbook of Psychiatry (pp. 351 - 361). : Oxford University Press.
    • Lloyd SE, Rossor M, Fox N, Mead S, Collinge J (2009). HECTD2, a candidate susceptibility gene for Alzheimer's disease on 10q.. BMC Med Genet, 10, 90 - . doi:10.1186/1471-2350-10-90
    • Mead S, Rudge P, Hudson F, Walker S, Darbyshire J, Collinge J, PRION-1 Investigators (2009). Clinical trials and methodological problems in prion diseases Reply. LANCET NEUROL, 8(9), 782 - 783.
    • Hosszu LLP, Trevitt CR, Jones S, Batchelor M, Scott DJ, Jackson GS, Collinge J, Waltho JP, Clarke AR (2009). Conformational properties of beta-PrP. Journal of Biological Chemistry, 284(33), 21981 - 21990. doi:10.1074/jbc.M809173200
    • Ingram RJ, Isaacs JD, Kaur G, Lowther DE, Reynolds CJ, Boyton RJ, Collinge J, Jackson GS, Altmann DM (2009). A role of cellular prion protein in programming T-cell cytokine responses in disease. The FASEB Journal, 23(6), 1672 - 1684. doi:10.1096/fj.08-116087
    • Lloyd SE, Grizenkova J, Pota H, Collinge J (2009). Shadoo (Sprn) and prion disease incubation time in mice. Mammalian Genome, 20(6), 367 - 374. doi:10.1007/s00335-009-9194-5
    • Antonyuk SV, Trevitt CR, Strange RW, Jackson GS, Sangar D, Batchelor M, Cooper S, Fraser C, Jones S, Georgiou T, Khalili-Shirazi A, Clarke AR, Hasnain SS, Collinge J (2009). Crystal structure of human prion protein bound to a therapeutic antibody. Proceedings of the National Academy of Sciences of the United States of America, 106(8), 2554 - 2558. doi:10.1073/pnas.0809170106
    • Mead S, Gajulapalli D, Walker S, Wroe S, Rudge P, Collinge J (2009). THE NATIONAL PRION MONITORING COHORT: A LONGITUDINAL OBSERVATIONAL STUDY OF UK HUMAN PRION INFECTION.
    • Siddique D, Wroe S, Hyare H, Webb T, Macfarlane R, Collinge J, Walker S, Yousry T, Thornton J (2009). Whole Brain MTR25% a Valuable Outcome Measure in Prion Disease Therapeutic Trials.
    • Tayebi M, Collinge J, Hawke S (2009). Unswitched immunoglobulin M response prolongs mouse survival in prion disease. Journal of General Virology, 90(3), 777 - 782. doi:10.1099/vir.0.005041-0
    • Nicoll A, Collinge J (2009). Preventing prion pathogenicity by targeting the cellular prion protein. Infectious Disorders - Drug Targets, 9(1), 48 - 57.
    • Lloyd SE, Maytham EG, Pota H, Grizenkova J, Molou E, Uphill J, Hummerich H, Whitfield J, Alpers MP, Mead S, Collinge J (2009). HECTD2 is associated with susceptibility to mouse and human prion disease.. PLoS Genet, 5(2), e1000383 - . doi:10.1371/journal.pgen.1000383
    • Mead S, Poulter M, Uphill J, Beck J, Whitfield J, Webb TEF, Campbell T, Adamson G, Deriziotis P, Tabrizi SJ, Hummerich H, Verzilli C, Alpers MP, Whittaker JC, Collinge J (2009). Genetic risk factors for variant Creutzfeldt–Jakob disease: a genome-wide association study. The Lancet Neurology, 8(1), 57 - 66. doi:10.1016/S1474-4422(08)70265-5
    • Collinge J (2009). Human prion diseases. In Zuckerman A (Ed.), Principles & practice of clinical virology (pp. 939 - 968). : John Wiley & Sons.
    • Kaski D, Mead S, Hyare H, Cooper S, Jampana R, Overell J, Knight R, Collinge J, Rudge P (2009). Variant CJD in an individual heterozygous for PRNP codon 129. LANCET, 374(9707), 2128 - 2128.

    2008

    • Cronier S, Gros N, Tattum MH, Jackson GS, Clarke AR, Collinge J, Wadsworth JD (2008). Detection and characterization of proteinase K-sensitive disease-related prion protein with thermolysin. Biochemical Journal, 416(2), 297 - 305. doi:10.1042/BJ20081235
    • Wadsworth JD, Powell C, Beck JA, Joiner S, Linehan J, Brandner S, Mead S, Collinge J (2008). Molecular diagnosis of human prion disease. In Hill AF (Ed.), Methods in molecular biology: prion protein protocols (pp. 197 - 228). : Humana Press.
    • Brandner S, Whitfield J, Boone K, Puwa A, O'Malley C, Linehan JM, Joiner S, Scaravilli F, Calder I, Alpers MP, Wadsworth JD, Collinge J (2008). Central and peripheral pathology of kuru: pathological analysis of a recent case and comparison with other forms of human prion disease. Philosophical Transactions of the Royal Society B: Biological Sciences, 363(1510), 3755 - 3763. doi:10.1098/rstb.2008.0091
    • Collinge J, Whitfield J, McKintosh E, Frosh A, Mead S, Hill AF, Brandner S, Thomas D, Alpers MP (2008). A clinical study of kuru patients with long incubation periods at the end of the epidemic in Papua New Guinea. Philosophical Transactions of the Royal Society B: Biological Sciences, 363(1510), 3725 - 3739. doi:10.1098/rstb.2008.0068
    • Collinge J, Alpers MP (2008). Reminiscences and reflections on kuru, personal and scientific. Philosophical Transactions of the Royal Society B: Biological Sciences, 363(1510), 3613 - . doi:10.1098/rstb.2008.0098
    • Wadsworth JDF, Joiner S, Linehan JM, Asante EA, Brandner S, Collinge J (2008). Review: The origin of the prion agent of kuru: molecular and biological strain typing. Philosophical Transactions of the Royal Society B: Biological Sciences, 363(1510), 3747 - 3753. doi:10.1098/rstb.2008.0069
    • Whitfield JT, Pako WH, Collinge J, Alpers MP (2008). Mortuary rites of the South Fore and kuru. Philosophical Transactions of the Royal Society B: Biological Sciences, 363(1510), 3721 - 3724. doi:10.1098/rstb.2008.0074
    • Webb TEF, Poulter M, Beck J, Uphill J, Adamson G, Campbell T, Linehan J, Powell C, Brandner S, Pal S, Siddique D, Wadsworth JD, Joiner S, Alner K, Petersen C, Hampson S, Rhymes C, Treacy C, Storey E, Geschwind MD, Nemeth AH, Wroe S, Collinge J, Mead S (2008). Phenotypic heterogeneity and genetic modification of P102L inherited prion disease in an international series. Brain, 131(10), 2632 - 2646. doi:10.1093/brain/awn202
    • Ratte S, Prescott SA, Collinge J, Jefferys JGR (2008). Hippocampal bursts caused by changes in NMDA receptor-dependent excitation in a mouse model of variant CJD. Neurobiology of Disease, 32(1), 96 - 104. doi:10.1016/j.nbd.2008.06.007
    • Webb TEF, Pal S, Siddique D, Heaney DC, Linehan JM, Wadsworth JDF, Joiner S, Beck J, Wroe SJ, Stevenson V, Brandner S, Mead S, Collinge J (2008). First report of Creutzfeldt-Jakob disease occurring in 2 siblings unexplained by PRNP mutation. Journal of Neuropathology and Experimental Neurology, 67(9), 838 - 841. doi:10.1097/NEN.0b013e318182f36e
    • O'Shea M, Maytham EG, Linehan JM, Brandner S, Collinge J, Lloyd SE (2008). Investigation of Mcp1 as a quantitative trait gene for prion disease incubation time in mouse. Genetics, 180(1), 559 - 566. doi:10.1534/genetics.108.090984
    • O'Shea M, Maytham EG, Linehan JM, Brandner S, Collinge J, Lloyd SE (2008). Investigation of mcp1 as a quantitative trait gene for prion disease incubation time in mouse.. Genetics, 180(1), 559 - 566. doi:10.1534/genetics.108.090894
    • Rohrer JD, Warren JD, Barnes J, Mead S, Beck J, Pepple T, Boyes R, Omar R, Collinge J, Stevens JM, Warrington EK, Rossor MN, Fox NC (2008). Mapping the progression of progranulin-associated frontotemporal lobar degeneration. Nature Clinical Practice Neurology, 4(8), 455 - 460. doi:10.1038/ncpneuro0869
    • Isaacs AM, Powell C, Webb TE, Linehan JM, Collinge J, Brandner S (2008). Lack of TAR-DNA binding protein-43 (TDP-43) pathology in human prion diseases. Neuropathology and Applied Neurobiology, 34(4), 446 - 456. doi:10.1111/j.1365-2990.2008.00963.x
    • White MD, Farmer M, Mirabile I, Brandner S, Collinge J, Mallucci GR (2008). Single treatment with RNAi against prion protein rescues early neuronal dysfunction and prolongs survival in mice with prion disease. Proceedings of the National Academy of Sciences of the United States of America, 105(29), 10238 - 10243. doi:10.1073/pnas.0802759105
    • Rohrer JD, Warren JD, Omar R, Mead S, Beck J, Revesz T, Holton J, Stevens JM, Al-Sarraj S, Pickering-Brown SM, Hardy J, Fox NC, Collinge J, Warrington EK, Rossor MN (2008). Parietal lobe deficits in frontotemporal lobar degeneration caused by a mutation in the progranulin gene. Archives of Neurology, 65(4), 506 - 513. doi:10.1001/archneur.65.4.506
    • Wadsworth JDF, Joiner S, Linehan JM, Desbruslais M, Fox K, Cooper S, Cronier S, Asante EA, Mead S, Brandner S, Hill AF, Collinge J (2008). Kuru prions and sporadic Creutzfeldt-Jakob disease prions have equivalent transmission properties in transgenic and wild-type mice.. Proceedings of the National Academy of Sciences of the United States of America, 105(10), 3885 - 3890. doi:10.1073/pnas.0800190105
    • Beck J, Rohrer JD, Campbell T, Isaacs A, Morrison KE, Goodall EF, Warrington EK, Stevens J, Revesz T, Holton J, Al-Sarraj S, King A, Scahill R, Warren JD, Fox NC, Rossor MN, Collinge J, Mead S (2008). A distinct clinical, neuropsychological and radiological phenotype is associated with progranulin gene mutations in a large UK series. Brain, 131(3), 706 - 720. doi:10.1093/brain/awm320
    • Wadsworth JDF, Powell C, Beck JA, Joiner S, Linehan JM, Brandner S, Mead S, Collinge J (2008). Molecular diagnosis of human prion disease. Methods in Molecular Biology, 459, 197 - 227. doi:10.1007/978-1-59745-234-2_14
    • Wadsworth JD, Collinge J (2008). Prions of vertebrates. In Mahy BWJ, Van Regenmoretl MHV (Ed.), Encyclopedia of virology (pp. 330 - 336). : Elsevier Academic Press.
    • Beck JA, Campbell TA, Adamson G, Poulter M, Uphill JB, Molou E, Collinge J, Mead S (2008). Association of a null allele of SPRN with variant Creutzfeldt-Jakob disease. Journal of Medical Genetics, 45(12), 813 - 817. doi:10.1136/jmg.2008.061804
    • Mead S, Poulter M, Beck J, Uphill J, Jones C, Ang CE, Mein CA, Collinge J (2008). Successful amplification of degraded DNA for use with high-throughput SNP genotyping platforms. Human Mutation, 29(12), 1452 - 1458. doi:10.1002/humu.20782
    • Mead S, Whitfield J, Poulter M, Shah P, Uphill J, Beck J, Campbell T, Al-Dujaily H, Hummerich H, Alpers MP, Collinge J (2008). Genetic susceptibility, evolution and the kuru epidemic. Philosophical Transactions of the Royal Society B: Biological Sciences, 363(1510), 3741 - 3746. doi:10.1098/rstb.2008.0087
    • Collinge J (2008). Review. Lessons of kuru research: background to recent studies with some personal reflections. Philosophical Transactions of the Royal Society B: Biological Sciences, 363(1510), 3689 - 3696. doi:10.1098/rstb.2008.0121
    • Collinge J, Alpers MP (2008). Introduction: It was an extraordinary meeting that is reflected in the proceedings published in this issue of the Philosophical Transactions of the Royal Society. Philosophical Transactions of the Royal Society B: Biological Sciences, 363(1510), 3607 - 3612.
    • Isaacs JD, Garden OA, Kaur G, Collinge J, Jackson GS, Altmann DM (2008). The cellular prion protein is preferentially expressed by CD4+ CD25+ Foxp3+ regulatory T cells.. Immunology, 125(3), 313 - 319. doi:10.1111/j.1365-2567.2008.02853.x
    • Powell AD, Toescu EC, Collinge J, Jefferys JGR (2008). Alterations in Ca2+-buffering in prion-null mice: Association with reduced afterhyperpolarizations in CA1 hippocampal neurons. Journal of Neuroscience, 28(15), 3877 - 3886. doi:10.1523/JNEUROSCI.0675-08.2008
    • van der Zee J, Urwin H, Engelborghs S, Bruyland M, Vandenberghe R, Dermaut B, De Pooter T, Peeters K, Santens P, De Deyn PP, Fisher EM, Collinge J, Isaacs AM, Van Broeckhoven C (2008). CHMP2B C-truncating mutations in frontotemporal lobar degeneration are associated with an aberrant endosomal phenotype in vitro.. Hum Mol Genet, 17(2), 313 - 322. doi:10.1093/hmg/ddm309
    • Collinge J, Alpers MP (2008). Introduction.. Philos Trans R Soc Lond B Biol Sci, 363(1510), 3607 - 3612. doi:10.1098/rstb.2008.0103

    2007

    • Webb T, Mead S, Poulter M, Beck J, Uphill J, Campbell T, Adamson G, Pal S, Siddique D, Treacy C, Brandner S, Wroe S, Collinge J (2007). Inherited prion disease with the P102L mutation: Update of a worldwide kindred originating in England and multiple unrelated European kindreds.
    • Rohrer JD, Warren JD, Omar R, Mead S, Beck J, Stevens JM, Revesz T, Holton J, Collinge J, Hardy J, Warrington EK, Fox NC, Rossor MN (2007). Parietal lobe deficits are a feature of frontotemporal lobar degeneration caused by a mutation in the progranulin gene.
    • Smithson S, Leonard S, James MA, King C, Newbury-Ecob RA, Wroe SJ, Collinge J, Mead S (2007). Inherited Creutzfeldt-Jakob disease: phenotypes, genotypes and public health implications.
    • Mead S, Webb TE, Campbell TA, Beck J, Linehan JM, Rutherfoord S, Joiner S, Wadsworth JD, Heckmann J, Wroe S, Doey L, King A, Collinge J (2007). Inherited prion disease with 5-OPRI: phenotype modification by repeat length and codon 129. Neurology, 69(8), 730 - 738. doi:10.1212/01.wnl.0000267642.41594.9d
    • Rohrer JD, Warren JD, Omar R, Barnes J, Mead S, Beck J, Collinge J, Stevens JM, Warrington EK, Rossor MN, Fox NC (2007). Longitudinal clinical, radiological and neuropsychological profile of an at-risk family member from a kindred with progranulin-associated frontotemporal lobar degeneration.
    • Knight WD, Kennedy J, Mead S, Rossor MN, Beck J, Collinge J, Mummery C (2007). A novel presenilin 1 deletion (p.L166del) associated with early onset familial Alzheimer's disease. European Journal of Neurology, 14(7), 829 - 831. doi:10.1111/j.1468-1331.2007.01857.x
    • Wadsworth JD, Collinge J (2007). Update on human prion disease. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1772(6), 598 - 609. doi:10.1016/j.bbadis.2007.02.010
    • Kristiansen M, Deriziotis P, Dimcheff DE, Jackson GS, Ovaa H, Naumann H, Clarke AR, van Leeuwen FWB, Menendez-Benito V, Dantuma NP, Portis JL, Collinge J, Tabrizi SJ (2007). Disease-associated prion protein oligomers inhibit the 26S proteasome.. Molecular Cell, 26(2), 175 - 188. doi:10.1016/j.molcel.2007.04.001
    • Kovacs T, Beck JA, Papp MI, Lantos PL, Aranyi Z, Szirmai IG, Farsang M, Stuke A, Csillik A, Collinge J (2007). Familial prion disease in a Hungarian family with a novel 144-base pair insertion in the prion protein gene. Journal of Neurology, Neurosurgery and Psychiatry, 78(3), 321 - 323. doi:10.1136/jnnp.2006.104372
    • Mallucci GR, White MD, Farmer M, Dickinson A, Khatun H, Powell AD, Brandner S, Jefferys JG, Collinge J (2007). Targeting cellular prion protein reverses early cognitive deficits and neurophysiological dysfunction in prion-infected mice. Neuron, 53(3), 325 - 335. doi:10.1016/j.neuron.2007.01.005
    • Pal S, Jones S, Collinge J, Jackson GS (2007). A novel method for immunodiagnosis of variant Creutzfeldt- Jakob disease.
    • Webb T, Pal S, Siddique D, Heaney D, Brandner S, Wroe S, Stevenson V, Collinge J (2007). Sporadic Creutzfeldt-Jakob disease occurring in two siblings.
    • Pal S, Siddique D, Hyare H, Hewitt P, Collinge J, Wroe SJ (2007). Ante-mortem presentation of blood transfusion association vCJD.
    • Stone LA, Jackson GS, Collinge J, Wadsworth JD, Clarke AR (2007). Inhibition of proteinase K activity by copper(II) ions. Biochemistry, 46(1), 245 - 252.
    • Wadsworth JDF, Joiner S, Fox K, Linehan JM, Desbruslais M, Brandner S, Asante EA, Collinge J (2007). Prion infectivity in variant Creutzfeldt-Jakob disease rectum. Gut, 56(1), 90 - 94. doi:10.1136/gut.2006.091637
    • Mead S, Joiner S, Desbruslais M, Beck JA, O'Donoghue M, Lantos P, Wadsworth JD, Collinge J (2007). Creutzfeldt-Jakob disease, prion protein gene codon 129VV, and a novel PrPSc type in a young British woman. Archives of Neurology, 64(12), 1780 - 1784.
    • Khalili-Shirazi A, Kaisar M, Mallinson G, Jones S, Bhelt D, Fraser C, Clarke AR, Hawke SH, Jackson GS, Collinge J (2007). beta-PrP form of human prion protein stimulates production of monoclonal antibodies to epitope 91-110 that recognise native PrP(Sc). Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1774(11), 1438 - 1450. doi:10.1016/j.bbapap.2007.08.028
    • Siddique D, Wroe SJ, Hyare H, Webb TEF, Pal S, Collinge J, Walker S, Yousry T, Thornton J (2007). Correlation of magnetisation transfer ratio histogram measures with clinical disease severity in Inherited Prion Disease.
    • Pal S, Webb T, Alner K, Hewitt P, Brander S, Wadsworth JD, Collinge J, Wroe SJ (2007). Atypical presentation of variant Creutzfeldt-Jakob disease in a 73-year-old transfusion recipient.
    • Siddique D, Wroe S, Hyare H, Webb T, Pal S, Collinge J, Walker S, Yousry T, Thornton JS (2007). A correlation of magnetisation transfer ratio histogram measures with clinical disease severity in inherited prion disease.
    • Macfarlane RG, Wroe SJ, Collinge J, Yousry TA, Jager HR (2007). Neuroimaging findings in human prion disease. Journal of Neurology, Neurosurgery and Psychiatry, 78(7), 664 - 670.
    • Collinge J, Clarke AR (2007). A general model of prion strains and their pathogenicity. Science, 318(5852), 930 - 936. doi:10.1126/science.1138718

    2006

    • Wells MA, Jackson GS, Jones S, Hosszu LLP, Craven CJ, Clarke AR, Collinge J, Waltho JP (2006). A reassessment of copper(II) binding in the full-length prion protein. Biochemical Journal, 399(3), 435 - 444.
    • Wadsworth JDF, Collinge J (2006). Molecular pathology of prion diseases. In Turner M (Ed.), Creutzfeldt-Jakob disease: managing the risk of transfusion transmission (pp. 1 - 36). : American Association of Blood Banks Press.
    • Kotta K, Paspaltsis I, Bostantjopoulou S, Latsoudis H, Plaitakis A, Kazis D, Collinge J, Sklaviadis T (2006). Novel mutation of the PRNP gene of a clinical CJD case. BMC Infectious Diseases, 6, 169 - . doi:10.1186/1471-2334-6-169
    • Trevitt CR, Collinge J (2006). A systematic review of prion therapeutics in experimental models. BRAIN, 129, 2241 - 2265. doi:10.1093/brain/aw1150
    • Mead S, Poulter M, Beck J, Webb TEF, Campbell TA, Linehan JM, Desbruslais M, Joiner S, Wadsworth JDF, King A, Lantos P, Collinge J (2006). Inherited prion disease with six octapeptide repeat insertional mutation - molecular analysis of phenotypic heterogeneity. BRAIN, 129, 2297 - 2317. doi:10.1093/brain/aw1226
    • Tattum MH, Cohen-Krausz S, Thumanu K, Wharton CW, Khalili-Shirazi A, Jackson GS, Orlova EV, Collinge J, Clarke AR, Saibil HR (2006). Elongated oligomers assemble into mammalian PrP amyloid fibrils (vol 357, pg 975, 2006). J MOL BIOL, 361(4), 811 - 811. doi:10.1016/j.jmb.2006.06.001
    • Lewis PA, Tattum MH, Jones S, Bhelt D, Batchelor M, Clarke AR, Collinge J, Jackson GS (2006). Codon 129 polymorphism of the human prion protein influences the kinetics of amyloid formation. Journal of General Virology, 87(8), 2443 - 2449.
    • Lewis PA, Properzi F, Prodromidou K, Clarke AR, Collinge J, Jackson GS (2006). Removal of the glycosylphosphatidylinositol anchor from PrPSc by cathepsin D does not reduce prion infectivity. Biochemical Journal, 395(2), 443 - 448.
    • Skibinski G, Parkinson N, Fisher E, Collinge J, Freja Consortium (2006). Mutations in the endosomal ESCRTIII complex subunit CHMP2B in frontotemporal dementia.
    • Collinge J, Whitfield J, McKintosh E, Beck J, Mead S, Thomas DJ, Alpers MP (2006). Kuru in the 21st century - an acquired human prion disease with very long incubation periods. The Lancet, 367(9528), 2068 - 2074.
    • Tattum MH, Cohen-Krausz S, Khalili-Shirazi A, Jackson GS, Orlova EV, Collinge J, Clarke AR, Saibil HR (2006). Elongated oligomers assemble into mammalian PrP amyloid fibrils. Journal of Molecular Biology, 357(3), 975 - 985.
    • Hill AF, Joiner S, Beck JA, Campbell TA, Dickinson A, Poulter M, Wadsworth JDF, Collinge J (2006). Distinct glycoform ratios of protease resistant prion protein associated with PRNP point mutations. Brain, 129(3), 676 - 685.
    • Parkinson N, Ince PG, Smith MO, Highley R, Skibinski G, Andersen PM, Morrison KE, Pall HS, Hardiman O, Collinge J, Shaw PJ, EMC F, Study MRCPIALS, Consortium F (2006). ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B).. Neurology, 67(6), 1074 - 1077. doi:10.1212/01.wnl.0000231510.89311.8b
    • Jackson GS, ELECTROPHORETICS LTD, MEDICAL RESEARCH COUNCIL, UNIVERSITY COLLEGE LONDON, Ward MA, Collinge J, McGregor E, Leeds NL, Campbell J, Westbrook JA, Byers HL (2006). Diagnosis of neurodegenerative diseases.
    • Wroe SJ, Pal S, Siddique D, Hyare H, MacFarlane R, Joiner S, Linehan JM, Brandner S, Wadsworth JDF, Hewitt P, Collinge J (2006). Clinical presentation and pre-mortem diagnosis of variant Creutzfeldt-Jakob disease associated with blood transfusion: a case report. The Lancet, 368(9552), 2061 - 2067.
    • Rohrer JD, Mead S, Omar R, Poulter M, Warren JD, Collinge J, Rossor MN (2006). Prion protein (PRNP) genotypes in frontotemporal lobar degeneration syndromes. Annals of Neurology, 60(5), 616 - 616.
    • Isaacs JD, Ingram RJ, Collinge J, Altmann DM, Jackson GS (2006). The human prion protein residue 129 polymorphism lies within a cluster of epitopes for T cell recognition.. J Neuropathol Exp Neurol, 65(11), 1059 - 1068. doi:10.1097/01.jnen.0000240467.18381.49
    • Collinge J, Alpers MP (2006). Incubation period of human prion disease - Reply. LANCET, 368(9539), 914 - 915.
    • Mead S, Poulter M, Beck J, Webb TEF, Campbell TA, Linehan JM, Desbruslais M, Joiner S, Wadsworth JDF, King A, Lantos P, Collinge J (2006). Inherited prion disease with six octapeptide repeat insertional mutation - molecular analysis of phenotypic heterogeneity. Brain, 129(9), 2297 - 2317.
    • Trevitt CR, Collinge J (2006). A systematic review of prion therapeutics in experimental models. Brain, 129(9), 2241 - 2265.
    • Asante EA, Linehan JM, Gowland I, Joiner S, Fox K, Cooper S, Osiguwa O, Gorry M, Welch J, Houghton R, Desbruslais M, Brandner S, Wadsworth JD, Collinge J (2006). Dissociation of pathological and molecular phenotype of variant Creutzfeldt-Jakob disease in transgenic human prion protein 129 heterozygous mice. Proceedings of the National Academy of Sciences of the United States of America, 103(28), 10759 - 10764. doi:10.1073/pnas.0604292103
    • Waldman AD, Cordery RJ, MacManus DG, Godbolt A, Collinge J, Rossor MN (2006). Regional brain metabolite abnormalities in inherited prion disease and asymptomatic gene carriers demonstrated in vivo by quantitative proton magnetic resonance spectroscopy. Neuroradiology, 48(6), 428 - 433. doi:10.1007/s00234-006-0068-1
    • Wadsworth JDF, Joiner S, Linehan JM, Cooper S, Powell C, Mallinson G, Buckell J, Gowland I, Asante EA, Budka H, Brandner S, Collinge J (2006). Phenotypic heterogeneity in inherited prion disease (P102L) is associated with differential propagation of protease-resistant wild-type and mutant prion protein. Brain, 129(6), 1557 - 1569.
    • Godbolt AK, Beck JA, Collinge JC, Cipolotti L, Fox NC, Rossor MN (2006). A second family with familial AD and the V717L APP mutation has a later age at onset. Neurology, 66(4), 611 - 612.
    • Collinge J, Wadsworth JDF (2006). Molecular basis of prion diseases. In Siegel GJ, Albers RW, Brady ST, Price DL (Ed.), Basic neurochemistry: molecular, cellular, and medical aspects (pp. 791 - 803). : Elsevier Academic Press.
    • Webb T, Pal S, Siddique D, Brandner S, Wroe S, Collinge J (2006). Bilateral sequential alien limb in a pathologically confirmed case of Creutzfeldt-Jakob disease (SCJD).
    • Wells MA, Jelinska C, Hosszu LLP, Craven CJ, Clarke AR, Collinge J, Waltho JP, Jackson GS (2006). Multiple forms of copper (II) co-ordination occur throughout the disordered N-terminal region of the prion protein at pH 7.4. Biochemical Journal, 400(3), 501 - 510.

    2005

    • Mead S, Prout K, Collinge J (2005). Questionnaire to reduce the risk of iatrogenic prion disease transmission. Journal of Hospital Infection, 60(4), 378 - 379.
    • McKintosh E, Jackson G, Flechsig E, Prodromidou K, Hirsch P, Linehan J, Brandner S, Clarke A, Weissmann C, Collinge J (2005). A detergent-enzyme method for effective prion decontamination of surgical steel.
    • Hosszu LL, Wells MA, Jackson GS, Jones S, Batchelor M, Clarke AR, Craven CJ, Waltho JP, Collinge J (2005). Definable equilibrium states in the folding of human prion protein. Biochemistry, 44(50), 16649 - 16657.
    • Khalili-Shirazi A, Summers L, Linehan J, Mallinson G, Anstee D, Hawke S, Jackson GS, Collinge J (2005). PrP glycoforms are associated in a strain-specific ratio in native PrPSc. Journal of General Virology, 86(9), 2635 - 2644.
    • Kennedy A, Siddique D, Thomas DJ, Hill D, Tolley N, Collinge J (2005). Tonsil biopsy in the investigation of suspected variant Creutzfeldt-Jakob disease - A cohort study of 50 patients.
    • Hirsch N, Beckett A, Collinge J, Scaravilli F, Tabrizi S, Berry S (2005). Lymphocyte contamination of laryngoscope blades - a possible vector for transmission of variant Creutzfeldt-Jakob disease. Anaesthesia, 60(7), 664 - 667.
    • Khalili-Shirazi A, Quaratino S, Londei M, Summers L, Tayebi M, Clarke AR, Hawke SH, Jackson GS, Collinge J (2005). Protein conformation significantly influences immune responses to prion protein. The Journal of Immunology, 174(6), 3256 - 3263.
    • Lloyd SE, Collinge J (2005). Genetic susceptibility to Prion diseases in humans and mice. Current Genomics, 6(1), 1 - 11.
    • Khalili-Shirazi A, Quaratino S, Londei M, Jackson G, Collinge J (2005). Protein conformation influences immune responses to prion protein..
    • Collinge J (2005). Creutzfeldt-Jakob disease and other prion diseases. In O'Brien JT, Ames D, Burns A (Ed.), Dementia (pp. 763 - 776). : Oxford University Press.
    • Siddique D, Kennedy A, Thomas D, Wroe S, Stevens J, Wadsworth J, Brandner S, Linehan J, Joiner S, Jones J, Frosh A, Hill D, Tolley N, Rossor M, Collinge J (2005). Tonsil biopsy in the investigation of suspected variant Creutzfeldt-.Jakob disease - A cohort study of 50 patients.
    • Wroe S, Thomas D, Rossor M, Walker A, Keogh G, Siddique D, Webb T, Pal S, Darbyshire J, Collinge J (2005). PRION-1 TRIAL: Therapies for human prion disease (ISRCTN06722585).
    • Joiner S, Linehan JM, Brandner S, Wadsworth JDF, Collinge J (2005). High levels of disease related prion protein in the ileum in variant Creutzfeldt-Jakob disease. Gut, 54(10), 1506 - 1508.
    • Kristiansen M, Messenger MJ, Klohn PC, Brandner S, Wadsworth JD, Collinge J, Tabrizi SJ (2005). Disease-related prion protein forms aggresomes in neuronal cells leading to caspase-activation and apoptosis. Journal of Biological Chemistry, 280(46), 38851 - 38861. doi:10.1074/jbc.M506600200
    • Skibinski G, Parkinson NJ, Brown JM, Chakrabarti L, Lloyd SL, Hummerich H, Nielsen JE, Hodges JR, Spillantini MG, Thusgaard T, Brandner S, Brun A, Rossor MN, Gade A, Johannsen P, Sorensen SA, Gydesen S, EMC F, Collinge J (2005). Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia. NAT GENET, 37(8), 806 - 808. doi:10.1038/ng1609
    • Collinge J (2005). Molecular neurology of prion disease. Journal of Neurology, Neurosurgery and Psychiatry, 76(7), 906 - 919.
    • Cordery RJ, Alner K, Cipolotti L, Ron M, Kennedy A, Collinge J, Rossor MN (2005). The neuropsychology of variant CJD: a comparative study with inherited and sporadic forms of prion disease. Journal of Neurology, Neurosurgery and Psychiatry, 76(3), 330 - 336.
    • Jackson GS, McKintosh E, Flechsig E, Prodromidou K, Hirsch P, Linehan J, Brandner S, Clarke AR, Weissmann C, Collinge J (2005). An enzyme-detergent method for effective prion decontamination of surgical steel. Journal of General Virology, 86(3), 869 - 878.
    • Mallucci G, Collinge J (2005). Rational targeting for prion therapeutics. Nature Reviews Neuroscience, 6(1), 23 - 34.
    • Jones S, Batchelor M, Bhelt D, Clarke AR, Collinge J, Jackson GS (2005). Recombinant prion protein does not possess SOD-1 activity. Biochemical Journal, 392(2), 309 - 312.

    2004

    • Hill AF, Collinge J (2004). Prion strains and species barriers.. Contrib Microbiol, 11, 33 - 49.
    • Lloyd SE, Thompson SR, Beck JA, Linehan JM, Wadsworth JD, Brandner S, Collinge J, Fisher EMC (2004). Identification and characterization of a novel mouse prion gene allele.. Mamm Genome, 15(5), 383 - 389. doi:10.1007/s00335-004-3041-5
    • Beck JA, Poulter M, Campbell T, Uphill JB, Adamson G, Geddes JF, Revesz T, Davis M, Wood NW, Collinge J, Tabrizi SJ (2004). Nuclear somatic mosaicism in sporadic early-onset Alzheimer's disease.
    • Medical Research COUNCIL, Jackson GS, Collinge J, Clarke AR (2004). Prion decontamination.
    • Asante EA, Li YG, Gowland I, Jefferys JG, Collinge J (2004). Pathogenic human prion protein rescues PrP null phenotype in transgenic mice. Neuroscience Letters, 360(1-2), 33 - 36.
    • Brown J, Gydesen S, Johannsen P, Gade A, Skibinski G, Chakrabarti L, Brun A, Spillantini M, Yancopoulou D, Thusgaard T, Sorensen A, Fisher E, Collinge J, FReJA (2004). Frontotemporal dementia linked to chromosome 3.. Dement Geriatr Cogn Disord, 17(4), 274 - 276. doi:10.1159/000077153
    • Hill AF, Asante EA, Collinge J (2004). Bioassays for prions. In Nunnally BK, Krull IS (Ed.), Prions and mad cow disease (pp. 151 - 179). : Marcel Dekker.
    • Collinge J (2004). Human prion diseases. In Zuckerman AJ, Banatvala JE, Pattison JR, Griffiths PD, Schoub BD (Ed.), Principles and practice of clinical virology (pp. 779 - 811). : John Wiley.
    • Beck JA, Poulter M, Campbell TA, Uphill JB, Adamson G, Geddes JF, Revesz T, Davis MB, Wood NW, Collinge J, Tabrizi SJ (2004). Somatic and germline mosaicism in sporadic early-onset Alzheimer's disease. Human Molecular Genetics, 13(12), 1219 - 1224. doi:10.1093/hmg/ddh134
    • Wadsworth JD, Asante EA, Desbruslais M, Linehan JM, Joiner S, Gowland I, Welch J, Stone L, Lloyd SE, Hill AF, Brandner S, Collinge J (2004). Human prion protein with valine 129 prevents expression of variant CJD phenotype. Science, 306(5702), 1793 - 1796. doi:10.1126/science.1103932
    • Hafezparast M, Brandner S, Linehan J, Martin JE, Collinge J, Fisher EMC (2004). Prion disease incubation time is not affected in mice heterozygous for a dynein mutation. Biochemical and Biophysical Research Communications, 326(1), 18 - 22.
    • Mallucci G, Collinge J (2004). Update on Creutzfeldt-Jakob disease. Current Opinion in Neurology, 17(6), 641 - 647.
    • Godbolt A, Beck J, Collinge J, Garrard P, Warren JD, Fox NC, Rossor MN (2004). A presenilin 1 R2781 mutation presenting with language impairment. Neurology, 63(9), 1702 - 1704.
    • Frosh A, Smith LC, Jackson CJ, Linehan JM, Brandner S, Wadsworth JDF, Collinge J (2004). Analysis of 2000 consecutive UK tonsillectomy specimens for disease-related prion protein. The Lancet, 364(9441), 1260 - 1262.
    • Beringue V, Vilette D, Mallinson G, Archer F, Kaisar M, Tayebi M, Jackson GS, Clarke AR, Laude H, Collinge J, Hawke S (2004). PrPSc binding antibodies are potent inhibitors of prion replication in cell lines. Journal of Biological Chemistry, 279(38), 39671 - 39676.
    • Lloyd SE, Linehan JM, Desbruslais M, Joiner S, Buckell J, Brandner S, Wadsworth JD, Collinge J (2004). Characterization of two distinct prion strains derived from bovine spongiform encephalopathy transmissions to inbred mice. Journal of General Virology, 85(8), 2471 - 2478.
    • Tabrizi SJ, Beck JA, Poulter M, Campbell T, Uphill JB, Adamson G, Geddes JF, Revesz T, Davis M, Wood N, Collinge J (2004). Somatic mosaicism in sporadic early-onset Alzheimer's disease.
    • Hosszu LLP, Jackson GS, Trevitt CR, Jones S, Batchelor M, Bhelt D, Prodromidou K, Clarke AR, Waltho JP, Collinge J (2004). The residue 129 polymorphism in human prion protein does not confer susceptibility to Creutzfeldt-Jakob disease by altering the structure or global stability of PrPC. Journal of Biological Chemistry, 279(27), 28515 - 28521.
    • Kristiansen M, Klohn PC, Messenger MJ, Sutton LM, Podesta JE, Collinge J, Tabrizi SJ (2004). Prion infection renders neuronal cells more susceptible to proteasome inhibition and apoptotic stimuli.
    • Tayebi M, Enever P, Sattar Z, Collinge J, Hawke S (2004). Disease-associated prion protein elicits immunoglobulin M responses in vivo. Molecular Medicine, 10(7-12), 104 - 111.

    2003

    • Tabrizi SJ, Collinge J (2003). Transmissable spongiform encephalopathies of humans and animals. In Cohen J, Powderly WG (Ed.), Infectious diseases (pp. 297 - 305). : Mosby.
    • Wadsworth JD, Hill AF, Beck JA, Collinge J (2003). Molecular and clinical classification of human prion disease.. Br Med Bull, 66, 241 - 254.
    • Hill AF, Collinge J (2003). Subclinical prion infection. Trends in Microbiology, 11(12), 578 - 584.
    • Beringue V, Mallinson G, Kaisar M, Tayebi M, Sattar Z, Jackson G, Anstee D, Collinge J, Hawke S (2003). Regional heterogeneity of cellular prion protein isoforms in the mouse brain.. Brain, 126(Pt 9), 2065 - 2073. doi:10.1093/brain/awg205
    • Hill AF, Joiner S, Wadsworth JD, Sidle KC, Bell JE, Budka H, Ironside JW, Collinge J (2003). Molecular classification of sporadic Creutzfeldt-Jakob disease.. Brain, 126(Pt 6), 1333 - 1346.
    • King A, Doey L, Rossor M, Mead S, Collinge J, Lantos P (2003). Phenotypic variability in the brains of a family with a prion disease characterized by a 144-base pair insertion in the prion protein gene.. Neuropathol Appl Neurobiol, 29(2), 98 - 105.
    • Janssen JC, Beck JA, Campbell TA, Dickinson A, Fox NC, Harvey RJ, Houlden H, Rossor MN, Collinge J (2003). Early onset familial Alzheimer's disease: Mutation frequency in 31 families.. Neurology, 60(2), 235 - 239.
    • Orth M, Tabrizi SJ (2003). Models of Parkinson's disease.. Mov Disord, 18(7), 729 - 737. doi:10.1002/mds.10447
    • Hill AF, Collinge J (2003). Subclinical prion infection. In Rappocciolo E (Ed.), Trends in microbiology (pp. 578 - 584). : Oxford University Press.
    • MEDICAL RESEARCH COUNCIL, Jackson GS, Collinge J, Wadsworth JDF, Clarke AR, Hawke S (2003). Sarcosyl buffer and its use for the purification of prion protein.
    • MEDICAL RESEARCH COUNCIL, Jackson GS, Collinge J (2003). Method for determining susceptibility to prion disease.
    • Mallucci G, Dickinson A, Linehan J, Klohn PC, Brandner S, Collinge J (2003). Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis. Science, 302(5646), 871 - 874. doi:10.1126/science.1090187
    • Mead S, Heckmann J, Rutherfoord S, Poulter M, Collinge J (2003). Inherited prion disease caused by octapeptide repeat insertion: Genetic modifiers and haplotype background in large UK and South African families.
    • Ratte S, Collinge J, Jefferys JGR (2003). AMPA/KA receptor independent epileptiform bursts in the hippocampus of a mouse model of variant CJD.
    • Mead S, Stumpf MP, Whitfield J, Beck JA, Poulter M, Campbell T, Uphill JB, Goldstein D, Alpers M, EMC F, Collinge J (2003). Balancing selection at the prion protein gene consistent with prehistoric kurulike epidemics.. Science, 300(5619), 640 - 643. doi:10.1126/science.1083320
    • McKintosh E, Tabrizi SJ, Collinge J (2003). Prion diseases. Journal of Neurovirology, 9(2), 183 - 193.
    • Collinge J, Brandner S, Kennedy A, Rossor M, Smith P, Stevens J, Rudge P (2003). A 38-year-old man with a 9 month history of neurological and cognitive impairment. The Lancet Neurology, 2(3), 189 - 194.
    • White AR, Enever P, Tayebi M, Mushens R, Linehan J, Brandner S, Anstee D, Collinge J, Hawke S (2003). Monoclonal antibodies inhibit prion replication and delay the development of prion disease. Nature, 422(6927), 80 - 83. doi:10.1038/nature01457
    • Johannsen P, Gydesen S, Brown J, Gade A, Chakrabarti L, Skibinski G, Englund E, Brun A, Rossor M, Soerensen SA, Fisher E, Collinge J (2003). Chromosome 3 related frontotemporal dementia. INT PSYCHOGERIATR, 15, 81 - 81.
    • Hill AF, Collinge J (2003). Subclinical prion infection in humans and animals.. Br Med Bull, 66, 161 - 170.

    2002

    • Mead S, Mahal S, Beck J, Farall M, Fisher EMC, Collinge J (2002). Identification of new prion disease susceptibility loci. J NEUROL NEUROSUR PS, 73(2), 223 - 223.
    • Hill AF, Collinge J (2002). Species-barrier-independent prion replication in apparently resistant species. Apmis, 110(1), 44 - 53.
    • Collinge J, Wadsworth J (2002). Distribution of infectivity in variant Creutzfeldt-Jakob disease - Reply. LANCET, 359(9308), 801 - 801.
    • Asante EA, Linehan JM, Desbruslais M, Joiner S, Gowland I, Wood AL, Welch J, Hill AF, Lloyd SE, Wadsworth JD, Collinge J (2002). BSE prions propagate as either variant CJD-like or sporadic CJD-like prion strains in transgenic mice expressing human prion protein. The EMBO Journal, 21(23), 6358 - 6366.
    • Mallucci GR, Ratte S, Asante EA, Linehan J, Gowland I, Jefferys JGR, Collinge J (2002). Post-natal knockout of prion protein alters hippocampal CA1 properties, but does not result in neurodegeneration. The EMBO Journal, 21(3), 202 - 210.
    • Hill AF, Collinge J (2002). Strain variations and species barriers. In (Ed.), Prions - A challenge for science, medicine and public health systems (pp. 48 - 57). : Basel: Karger.
    • Joiner S, Linehan J, Brandner S, Wadsworth JD, Collinge J (2002). Irregular presence of abnormal prion protein in appendix in variant Creutzfeldt-Jakob disease. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 73(5), 597 - 598.
    • La Bella V, Collinge J, Pocchiari M, Piccoli F (2002). Variant Creutzfeldt-Jakob disease in an Italian woman. The Lancet, 360(9338), 997 - 998.
    • Lloyd SE, Uphill JB, Targonski PV, Fisher EM, Collinge J (2002). Identification of genetic loci affecting mouse-adapted bovine spongiform encephalopathy incubation time in mice. Neurogenetics, 4(2), 77 - 81.
    • Makrinou E, Collinge J, Antoniou M (2002). Genomic characterization of the human prion protein (PrP) gene locus. Mammalian Genome, 13(12), 696 - 703.
    • O'Riordan S, McMonagle P, Janssen JC, Fox NC, Farrell M, Collinge J, Rossor MN, Hutchinson M (2002). Presenilin-1 mutation (E280G), spastic paraparesis, and cranial MRI whitematter abnormalities. Neurology, 59(7), 1108 - 1110.
    • Janssen JC, Beck JA, Campbell TA, Dickinson A, Fox NC, Harvey RJ, Houlden H, Rosser MN, Collinge J (2002). Early onset familial alzheimer's disease: Mutation frequency in 31 families. J NEUROL NEUROSUR PS, 73(2), 219 - 219.
    • Janssen JC, Fox NC, Harvey RJ, Houlden H, Rossor MN, Beck JA, Campbell TA, Dickinson A, Collinge J (2002). Early-onset familial Alzheimer's disease: Mutation frequency in 31 families. NEUROBIOL AGING, 23(1), S311 - S311.
    • Makrinou E, Antoniou M, Collinge J, Collinge J (2002). Genomic characterisation of the human prion protein (PrP) gene locus.
    • Mallucci GR, Ratte S, Asante EA, Linehan J, Gowland I, Jefferys JGR, Collinge J (2002). Post-natal knockout of prion protein alters hippocampal CA1 properties, but does not result in neurodegeneration (vol 21, pg 202, 2002). EMBO J, 21(5), 1240 - 1240.
    • Asante EA, Gowland I, Linehan JM, Mahal SP, Collinge J (2002). Expression pattern of a mini human PrP gene promoter in transgenic mice.. Neurobiol Dis, 10(1), 1 - 7.
    • Gydesen S, Brown JM, Brun A, Chakrabarti L, Gade A, Johannsen P, Rossor M, Thusgaard T, Grove A, Yancopoulou D, Spillantini MG, EMC F, Collinge J, Sorensen SA (2002). Chromosome 3 linked frontotemporal dementia (FTD-3).. Neurology, 59(10), 1585 - 1594.
    • Collinge J (2002). Molecular pathology of human prion disease. NEUROBIOL AGING, 23(1), S428 - S428.

    2001

    • Jackson GS, Collinge J (2001). The molecular pathology of CJD: old and new variants.. Mol Pathol, 54(6), 393 - 399.
    • Flechsig E, Hegyi I, Enari M, Schwarz P, Collinge J, Weissmann C (2001). Transmission of scrapie by steel-surface-bound prions.. Mol Med, 7(10), 679 - 684.
    • Mead SH, Mahal SP, Farrall M, Fisher EMC, Collinge J (2001). Association of prion protein gene single nucleotide polymorphism haplotypes with Creutzfeldt-Jakob disease.. AM J HUM GENET, 69(4), 182 - 182.
    • Hasnain SS, Murphy LM, Strange RW, Grossmann JG, Clarke AR, Jackson GS, Collinge J (2001). XAFS study of the high-affinity copper-binding site of human PrP(91-231) and its low-resolution structure in solution.. J Mol Biol, 311(3), 467 - 473. doi:10.1006/jmbi.2001.4795
    • Jackson GS, Murray I, Hosszu LL, Gibbs N, Waltho JP, Clarke AR, Collinge J (2001). Location and properties of metal-binding sites on the human prion protein. Proceedings of the National Academy of Sciences of the United States of America, 98(15), 8531 - 8535. doi:10.1073/pnas.151038498
    • Beck JA, Mead S, Campbell TA, Dickinson A, Wientjens DP, Croes EA, Van Duijn CM, Collinge J (2001). Two-octapeptide repeat deletion of prion protein associated with rapidly progressive dementia.. Neurology, 57(2), 354 - 356.
    • Wadsworth JD, Joiner S, Hill AF, Campbell TA, Desbruslais M, Luthert PJ, Collinge J (2001). Tissue distribution of protease resistant prion protein in variant Creutzfeldt-Jakob disease using a highly sensitive immunoblotting assay. The Lancet, 358(9277), 171 - 180. doi:10.1016/S0140-6736(01)05403-4
    • Mahal SP, Asante EA, Antoniou M, Collinge J (2001). Isolation and functional characterisation of the promoter region of the human prion protein gene.. Gene, 268(1-2), 105 - 114.
    • Lloyd SE, Onwuazor ON, Beck JA, Mallinson G, Farrall M, Targonski P, Collinge J, Fisher EMC (2001). Identification of multiple quantitative trait loci linked to prion disease incubation period in mice.. Proceedings of the National Academy of Sciences of the United States of America, 98, 6279 - 6283. doi:10.1073/pnas.101130398
    • Clarke AR, Jackson GS, Collinge J (2001). The molecular biology of prion propagation. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES, 356(1406), 185 - 194.
    • Pepys HB, Collinge J, Barron LD, Collinge J, Masel J, Tahari-Alaoui A, Lansbury P, Exley C, Feizi T (2001). The molecular biology of prion propagation - Discussion. PHILOS T R SOC B, 356(1406), 194 - 195.
    • Mead S, Mahal SP, Beck J, Campbell T, Farrall M, Fisher EMC, Collinge J (2001). Sporadic - but not variant - Creutzfeldt-Jakob disease is associated with polymorphisms upstream of PRNP Exon 1. AM J HUM GENET, 69(6), 1225 - 1235. doi:10.1086/324710
    • Asante EA, Collinge J (2001). Transgenic studies of the influence of the PrP structure on TSE diseases.. Adv Protein Chem, 57, 273 - 311.
    • Kulczycki J, Collinge J, Lojkowska W, Parnowski T, Wierzba-Bobrowicz T (2001). Report on the first polish case of the Gerstmann-Sträussler-Scheinker syndrome.. Folia Neuropathol, 39(1), 27 - 31.
    • Imperial College Innovations LTD, Collinge J, Clarke AR, Waltho JP, Jackson GS, Hosszu LLP (2001). Fragments of cellular prion protein and methods useful in the diagnosis and treatment of prion diseases.
    • Makrinou E, Collinge J, Antoniou M (2001). Genomic characterisation of the human PRNP/PRND locus.. AM J HUM GENET, 69(4), 369 - 369.
    • Jackson GS, Beck JA, Navarrete C, Brown J, Sutton PM, Contreras M, Collinge J (2001). Pathogenesis - HLA-DQ7 antigen and resistance to variant CJD. NATURE, 414(6861), 269 - 270.
    • Hill AF, Collinge J (2001). Strain variations and species barriers.. Contrib Microbiol, 7, 48 - 57.
    • Murphy LM, Hasnain SS, Strange RW, Grossmann JG, Clarke AR, Jackson GS, Collinge J (2001). A new copper binding site in N-terminal truncated recombinant human PrP91-231. J INORG BIOCHEM, 86(1), 351 - 351.
    • Pepys MB, Caughey B, Kelly JW, Ellis RJ, Collinge J, Perutz MF, Masel J (2001). Prion protein interconversions - Discussion. PHILOS T R SOC B, 356(1406), 200 - 202.
    • Jackson GS, Beck JA, Navarrete C, Brown J, Sutton PM, Contreras M, Collinge J (2001). HLA-DQ7 antigen and resistance to variant CJD. Nature, 414(6861), 269 - 270.
    • Janssen JC, Lantos PL, Fox NC, Harvey RJ, Beck J, Dickinson A, Campbell TA, Collinge J, Hanger DP, Cipolotti L, Stevens JM, Rossor MN (2001). Autopsy-confirmed familial early-onset Alzheimer disease caused by the L153V presenilin 1 mutation. Archives of Neurology, 58(6), 953 - 958.
    • Collinge J (2001). Prion diseases of humans and animals: their causes and molecular basis.. Annu Rev Neurosci, 24, 519 - 550. doi:10.1146/annurev.neuro.24.1.519
    • Sattar Z, Tayebi M, Kaisar M, Khalili-Shirazi A, Mallinson G, Jackson GS, Collinge J, Hawke S (2001). PrP conformation and genotype profoundly influence anti-PrP antibody specificity.

    2000

    • Mead S, Beck J, Dickinson A, Fisher E, Collinge J (2000). Examination of the human prion protein-like gene doppel for genetic susceptibility to sporadic and variant Creutzfeldt-Jakob disease.. Neuroscience Letters, 290(2), 117 - 120.
    • King A, Rossor M, Doey L, Collinge J, Lantos P (2000). Phenotypic variations in a familiar prion disease characterised by a 144 base pair insertion in the Prion protein gene. BRAIN PATHOL, 10(4), 669 - 669.
    • Hill AF, Joiner S, Linehan J, Desbruslais M, Lantos PL, Collinge J (2000). Species-barrier-independent prion replication in apparently resistant species.. Proc Natl Acad Sci U S A, 97(18), 10248 - 10253.
    • Barrow PA, Mallucci G, Collinge J, Jefferys JGR (2000). Rescue of a physiological phenotype in mice with ablated PrP gene but expressing a transgene cassette for PrP. J PHYSIOL-LONDON, 523, 203P - 204P.
    • Collinge J (2000). Creutzfeldt-Jakob disease and other prion diseases. In O'Brien JT, Ames D, Burns A (Ed.), Dementia (pp. - ). : Hodder Arnold.
    • Janssen JC, Hall M, Fox NC, Harvey RJ, Beck J, Dickinson A, Campbell T, Collinge J, Lantos PL, Cipolotti L, Stevens JM, Rossor MN (2000). Alzheimer's disease due to an intronic presenilin-1 (PSEN1 intron 4) mutation: a clinicopathological study. Brain, 123, 894 - 907.
    • D-GEN LTD, Collinge J, Wadsworth JDF, Thomas PJD (2000). Method to type prion proteins.
    • D-GEN LTD, Collinge J, Clarke AR, Jackson GS (2000). Biological materials and methods useful in the diagnosis and treatment of prion diseases.
    • Jackson GS, Collinge J (2000). Prion disease - the propagation of infectious protein topologies. MICROBES INFECT, 2(12), 1445 - 1449.
    • Collinge J (2000). Human prion diseases. BRAIN PATHOL, 10(4), 607 - 607.
    • Collinge J (2000). Prion diseases. In Ledingham JGG, Warrell DA (Ed.), Concise Oxford textbook of medicine (pp. 1307 - 1311). : Oxford University Press.

    1999

    • Jackson GS, Hill AF, Joseph C, Hosszu L, Power A, Waltho JP, Clarke AR, Collinge J (1999). Multiple folding pathways for heterologously expressed human prion protein.. Biochim Biophys Acta, 1431(1), 1 - 13.
    • Jackson GS, Hosszu LL, Power A, Hill AF, Kenney J, Saibil H, Craven CJ, Waltho JP, Clarke AR, Collinge J (1999). Reversible conversion of monomeric human prion protein between native and fibrilogenic conformations.. Science, 283(5409), 1935 - 1937.
    • Hill AF, Antoniou M, Collinge J (1999). Protease-resistant prion protein produced in vitro lacks detectable infectivity.. J Gen Virol, 80 ( Pt 1), 11 - 14.
    • Mallucci GR, Campbell TA, Dickinson A, Beck J, Holt M, Plant G, de Pauw KW, Hakin RN, Clarke CE, Howell S, Davies-Jones GA, Lawden M, Smith CM, Ince P, Ironside JW, Bridges LR, Dean A, Weeks I, Collinge J (1999). Inherited prion disease with an alanine to valine mutation at codon 117 in the prion protein gene.. Brain, 122 ( Pt 10), 1823 - 1837.
    • Palmer MS, Beck JA, Campbell TA, Humphries CB, Roques PK, Fox NC, Harvey R, Rossor MN, Collinge J (1999). Pathogenic presenilin 1 mutations (P436S & I143F) in early-onset Alzheimer's disease in the UK. Mutations in brief no. 223. Online.. Hum Mutat, 13(3), 256 - . doi:10.1002/(SICI)1098-1004(1999)13:3<256::AID-HUMU12>3.0.CO;2-M
    • Wadsworth JD, Jackson GS, Hill AF, Collinge J (1999). Molecular biology of prion propagation.. Curr Opin Genet Dev, 9(3), 338 - 345.
    • Collinge J (1999). Variant Creutzfeldt-Jakob disease.. Lancet, 354(9175), 317 - 323. doi:10.1016/S0140-6736(99)05128-4
    • Hill AF, Butterworth RJ, Joiner S, Jackson G, Rossor MN, Thomas DJ, Frosh A, Tolley N, Bell JE, Spencer M, King A, Al Sarraj S, Ironside JW, Lantos PL, Collinge J (1999). Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples. The Lancet, 353, 183 - 189.
    • Ashworth A, Lloyd S, Brown J, Gydesen S, Sorensen SA, Brun A, Englund E, Humphreys C, Housman D, Badura M, Stanton V, Taylor K, Cameron J, Munroe D, Johansson J, Rossor M, Fisher EMC, Collinge J (1999). Molecular genetic characterisation of frontotemporal dementia on chromosome 3. Dementia and Geriatric Cognitive Disorders, 10(Suppl.1), 93 - 101.
    • Almer G, Hainfellner JA, Brücke T, Jellinger K, Kleinert R, Bayer G, Windl O, Kretzschmar HA, Hill A, Sidle K, Collinge J, Budka H (1999). Fatal familial insomnia: a new Austrian family.. Brain, 122 ( Pt 1), 5 - 16.
    • Telling GC, Collinge J (1999). Transmissible spongiform encephalopathies of humans and animals. In Armstrong D, Cohen J (Ed.), Central nervous system (pp. 191 - 195). : Mosby International.
    • Hosszu LL, Baxter NJ, Jackson GS, Power A, Clarke AR, Waltho JP, Craven CJ, Collinge J (1999). Structural mobility of the human prion protein probed by backbone hydrogen exchange.. Nat Struct Biol, 6(8), 740 - 743. doi:10.1038/11507
    • Wadsworth JD, Hill AF, Joiner S, Jackson GS, Clarke AR, Collinge J (1999). Strain-specific prion-protein conformation determined by metal ions.. Nat Cell Biol, 1(1), 55 - 59. doi:10.1038/9030

    1998

    • Collinge J (1998). Assessing risks of BSE transmission to humans.
    • Collinge J, Beck J, Campbell TA, Desbuslais M, Gowland I, Hill A, Mahal S, Meads J, Sidle KCL, Jefferys JGR (1998). Molecular, genetic and transgenetic studies of human prion disease.
    • Jackson G, Hill A, Joseph C, Clarke A, Collinge J (1998). Structural properties of recombinant human prion protein.
    • Collinge J (1998). Human prion diseases: Aetiology and clinical features. In Growdon JH, Rossor M (Ed.), The dementias (pp. 113 - 148). : Newton, Butterworth-Heinemann.
    • Collinge J, Hawke S (1998). B lymphocytes in prion neuroinvasion: central or peripheral players?. Nat Med, 4(12), 1369 - 1370. doi:10.1038/3955
    • Fisher E, Telling G, Collinge J (1998). Prions and the prion disorders.. Mamm Genome, 9(7), 497 - 502.
    • Piccardo P, Langeveld JP, Hill AF, Dlouhy SR, Young K, Giaccone G, Rossi G, Bugiani M, Bugiani O, Meloen RH, Collinge J, Tagliavini F, Ghetti B (1998). An antibody raised against a conserved sequence of the prion protein recognizes pathological isoforms in human and animal prion diseases, including Creutzfeldt-Jakob disease and bovine spongiform encephalopathy.. Am J Pathol, 152(6), 1415 - 1420.
    • Sidle K, Will B, Lantos P, Collinge J (1998). Transmission studies of fatal familial insomnia.
    • Alvarez XA, Barker S, Binetti G, Boller F, Bracco L, Breteler M, Brun A, Cacabelos R, Caims N, Cappa S, Cipolotti L, Collinge J, Englund E, Forleo P, Forstl H, Grassi E, Harvey R, Hodges J, Gustafson L, Kurz A, Lantos P, Lautenschlager N, Lebert F, Muggia S, Pasquier F, Passant U, Ravid R, Rossor M, Sorbi S, Spinnler H, Stevens J, Van Swieten J, Warrington E, Xuereb J (1998). Provisional clinical and neuroradiological criteria for the diagnosis of Pick's disease. European Journal of Neurology, 5, 519 - 520.
    • Harvey RJ, Ellison D, Hardy J, Hutton M, Rogues P, Collinge J, Fox NC, Rossor MN (1998). Chromosome 14 familial Alzheimer's disease: the clinical and neuropathological characteristics of a family with a leucine->serine (L250S) substitution at codon 250 of the presenilin 1 gene. Journal of Neurology, Neurosurgery and Psychiatry, 64, 44 - 49.
    • Brett FM, Cervenakova L, Collinge J, Farrell MA, Gibbs CJ, Traynor B, Staunton H (1998). Sporadic fatal dementia with thalamic gliosis and D178N PrP genotype but with absence of spongiform change and negative PrP immunocytochemistry.. J NEUROPATH EXP NEUR, 57(5), 492 - 492.
    • Jackson GS, Hill A, Joseph C, Clarke AR, Collinge J (1998). Structural properties of recombinant human prion protein. In Morrison DO (Ed.), Prions and brain diseases in animals and humans. (pp. 197 - 202). : Plenum.
    • Hill AF, Sidle KC, Joiner S, Keyes P, Martin TC, Dawson M, Collinge J (1998). Molecular screening of sheep for bovine spongiform encephalopathy.. Neurosci Lett, 255(3), 159 - 162.
    • Collinge J, Rossor MN, Thomas D, Frosh A, Tolley N (1998). Diagnosis of Creutzfeldt-Jakob disease by measurement of S100 protein in serum - Tonsil biopsy helps diagnose new variant Creutzfeldt-Jakob disease. BRIT MED J, 317(7156), 472 - 472.

    1997

    • Hill AF, Will RG, Ironside J, Collinge J (1997). Type of prion protein in UK farmers with Creutzfeldt-Jakob disease. LANCET, 350(9072), 188 - 188.
    • Lantos PL, Bhatia K, Doey LJ, al-Sarraj S, Doshi R, Beck J, Collinge J (1997). Is the neuropathology of new variant Creutzfeldt-Jakob disease and kuru similar?. Lancet, 350(9072), 187 - 188.
    • Budka H, Hainfellner JA, Almer G, BrOcke T, Windl O, Kretzschmar HA, Hill A, Collinge J (1997). A new Austrian family with fatal familial insomnia: Brain pathology without detectable PrPres. BRAIN PATHOL, 7(4), 1267 - 1267.
    • Piccardo P, Tagliavini F, Dlouhy SR, Young K, Seiler C, Rossi G, Hill AF, Bugiani M, Bugiani O, Langeveld JPM, Collinge J, Ghetti B (1997). Species and disease specific prion protein (PrP) isoforms are detected by antibodies (abs) raised against a highly conserved mid-region sequence. BRAIN PATHOL, 7(4), 1248 - 1248.
    • Collinge J, Palmer MS, Sidle KCL, Hill AF, Gowland I, Meads J, Asante E, Bradley R, Doey LJ, Lantos PL (1997). Unaltered susceptibility to BSE in transgenic mice expressing human prion protein (vol 378, pg 779, 1995). NATURE, 389(6650), 526 - 526.
    • Hill AF, Desbruslais M, Joiner S, Sidle KCL, Gowland I, Collinge J, Doey LJ, Lantos P (1997). The same prion strain causes vCJD and BSE. NATURE, 389(6650), 448 - 450.
    • Mallucci GR, Collinge J (1997). Neuropsychiatric presentations of prion disease. CURR OPIN PSYCHIATR, 10(1), 59 - 62.
    • Collinge J (1997). Human prion diseases and bovine spongiform encephalopathy (BSE).. Hum Mol Genet, 6(10), 1699 - 1705.
    • Piccardo P, Tagliavini F, Dlouhy SR, Young K, Seiler C, Rossi G, Hill AF, Bugiani O, Collinge J, Ghetti B (1997). An antiserum to residues 95-108 of human PrP detects PrPres in a variety of human and animal prion diseases.. J NEUROPATH EXP NEUR, 56(5), 73 - 73.
    • Hill AF, Zeidler M, Ironside J, Collinge J (1997). Diagnosis of new variant Creutzfeldt-Jakob disease by tonsil biopsy.. Lancet, 349(9045), 99 - 100. doi:10.1016/S0140-6736(97)24002-X
    • Collinge J, Hill AF, Sidle KCL, Ironside J (1997). Biochemical typing of scrapie strains - Reply. NATURE, 386(6625), 564 - 564.
    • Colling SB, Khana M, Collinge J, Jefferys JG (1997). Mossy fibre reorganization in the hippocampus of prion protein null mice.. Brain Res, 755(1), 28 - 35.
    • Basun H, Almkvist O, Axelman K, Brun A, Campbell TA, Collinge J, Forsell C, Froelich S, Wahlund LO, Wetterberg L, Lannfelt L (1997). Clinical characteristics of a chromosome 17-linked rapidly progressive familial frontotemporal dementia.. Arch Neurol, 54(5), 539 - 544.
    • Collinge J, Hill AF, Ironside J, Zeidler M (1997). Diagnosis of new variant Creutzfeldt-Jakob disease by tonsil biopsy - Reply. LANCET, 349(9061), 1323 - 1323.
    • Lachmann P, Allen I, Anderson R, Biggs P, Bostock C, Collinge J, Heap B, Kimberlin R, Klug A, Raff M, Swales J, Southwood R, Wilesmith J, Will B, Weissman C (1997). Update on BSE. INTERDISCIPL SCI REV, 22(3), 181 - 186.
    • Budka H, Hainfellner JA, Jellinger K, Kleinert R, Maier H, Pilz P, Sciot R, Martin JJ, BojsenMoller M, Laursen H, StTeglbjaerg P, Haltia M, Kovanen J, Delisle MB, Dormont D, Lasmezas C, Gray F, Hauw JJ, Seilhean D, Heldt N, Mikol J, Vital C, Foncin JF, ElHachimi K, Kopp N, Bergmann M, Bilzer T, CervosNavarro J, Diringer H, Feiden W, Goebel HH, Bohl J, Gullotta F, Jendroska K, Kretzschmar HA, Linke RP, Meyermann R, Boellaard JW, Mehraein P, Schlote W, Schroder JM, Schroder R, Volk B, Walter GF, Hori A, Wiestler OD, Balloyannis SJ, Davaki P, Patsouris E, Georgsson G, Farrell M, Keohane C, Bugiani O, Macchi G, Masullo C, Costanzi G, Pocchiari M, Rizzutto N, Schiffer D, Trabattoni GR, Giangaspero F, Jansen GH, Grinde B, Mork SJ, Skullerud K, Lima C, Pimentel J, CruzSanchez FF, Berciano JA, MartinezLage J, Navarro C, Cabello A, Brun A, Kristensson K, Lundberg PO, Olsson Y, Collinge J, Esiri MM, Graham D, Ironside JW, Lantos PL, MacKenzie JM, Scaravilli F, Weller RO, Will RG, Allen IV, Mirakhur M, Majtenyi K, Liberski PP, Petrescu A, Mitrova E, Popovic M, Aguzzi A, Janzer RC, Pizzolato G, Stamm B, Vandevelde M, Masters CL, Tateishi J, Kitamoto T, Brown P (1997). The human prion diseases: from neuropathology to pathobiology and molecular genetics - Final report of an EU Concerted Action. NEUROPATH APPL NEURO, 23(5), 416 - 422.
    • Aguzzi A, Collinge J (1997). Post-exposure prophylaxis after accidental prion inoculation.. Lancet, 350(9090), 1519 - 1520. doi:10.1016/S0140-6736(05)63941-4
    • Smith CJ, Drake AF, Banfield BA, Bloomberg GB, Palmer MS, Clarke AR, Collinge J (1997). Conformational properties of the prion octa-repeat and hydrophobic sequences.. FEBS Lett, 405(3), 378 - 384.
    • Collinge J, Hill AF, Sidle KCL, Ironside J (1997). Typing prion isoforms - Reply. NATURE, 386(6622), 233 - 234.
    • Esiri MM, Gordon WI, Collinge J, Patten JS (1997). Peripheral neuropathy in Creutzfeldt-Jakob disease. NEUROLOGY, 48(3), 784 - 784.
    • Deslys JP, Lasmézas CI, Streichenberger N, Hill A, Collinge J, Dormont D, Kopp N (1997). New variant Creutzfeldt-Jakob disease in France.. Lancet, 349(9044), 30 - 31.
    • Collinge J (1997). Assessing risks of BSE transmission to humans. In Goebel K (Ed.), International seminar on nuclear war and planetary emergencies (pp. 54 - 54). : World Scientific.
    • Fox NC, Kennedy AM, Harvey RJ, Lantos PL, Roques P, Collinge J, Hardy J, Hutton M, Stevens JM, Warrington EK, Rossor MN (1997). Clinicopathological features of familial Alzheimer's disease associated with the M139V mutation in the presenilin 1 gene - pedigree but not mutation specific age at onset provides evidence for a further genetic factor. Brain, 120, 491 - 501.

    1996

    • Palmer MS, van Leeven RH, Mahal SP, Campbell TA, Humphreys CB, Collinge J (1996). Sequence variation in intron of prion protein gene, crucial for complete diagnostic strategies.. Hum Mutat, 7(3), 280 - 281. doi:10.1002/(SICI)1098-1004(1996)7:3<280::AID-HUMU17>3.0.CO;2-Z
    • Budka H, Aguzzi A, Brown P, Brucher JM, Bugiani O, Collinge J, Diringer H, Gullotta F, Haltia M, Hauw JJ, Ironside JW, Kretzschmar HA, Lantos PL, Masullo C, Pocchiari M, Schlote W, Tateishi J, Will RG (1996). Tissue handling in suspected Creutzfeldt-Jakob disease (CJD) and other human spongiform encephalopathies (prion diseases). PATHOLOGE, 17(2), 171 - 175.
    • Budka H, Aguzzi A, Brown P, Brucher JM, Bugiani O, Collinge J, Diringer H, Gullotta F, Haltia M, Hauw JJ, Ironside JW, Kretzschmar HA, Lantos PL, Masullo C, Pocchiari M, Schlote W, Tateishi J, Will RG (1996). [Consensus report: tissue handling in suspected Creutzfeldt-Jakob disease and other spongiform encephalopathies (prion diseases) in the human. European Union Biomed-1 Concerted Action].. Pathologe, 17(2), 171 - 175.
    • Campbell TA, Palmer MS, Will RG, Gibb WR, Luthert PJ, Collinge J (1996). A prion disease with a novel 96-base pair insertional mutation in the prion protein gene.. Neurology, 46(3), 761 - 766.
    • Collinge J, Beck J, Campbell T, Estibeiro K, Will RG (1996). Prion protein gene analysis in new variant cases of Creutzfeldt-Jakob disease. LANCET, 348(9019), 56 - 56.
    • Windl O, Dempster M, Estibeiro JP, Lathe R, de Silva R, Esmonde T, Will R, Springbett A, Campbell TA, Sidle KC, Palmer MS, Collinge J (1996). Genetic basis of Creutzfeldt-Jakob disease in the United Kingdom: a systematic analysis of predisposing mutations and allelic variation in the PRNP gene.. Hum Genet, 98(3), 259 - 264.
    • Tabrizi SJ, Scaravilli F, Howard RS, Collinge J, Rossor MN (1996). Creutzfeldt-Jakob disease in a young woman.. The Lancet, 347(9006), 945 - 948.
    • Collinge J (1996). Prion diseases. In Weatherall DJ, Ledingham J, Warrell D (Ed.), Oxford textbook of medicine (pp. 3977 - 3981). : Oxford University Press.
    • Colling SB, Collinge J, Jefferys JG (1996). Hippocampal slices from prion protein null mice: disrupted Ca(2+)-activated K+ currents.. Neurosci Lett, 209(1), 49 - 52.
    • Rossor MN, Fox NC, Beck J, Campbell TC, Collinge J (1996). Incomplete penetrance of familial Alzheimer's disease in a pedigree with a novel presenilin-1 gene mutation. LANCET, 347(9014), 1560 - 1560.
    • Collinge J (1996). New diagnostic tests for prion diseases.. N Engl J Med, 335(13), 963 - 965. doi:10.1056/NEJM199609263351310
    • Collinge J, Sidle KC, Meads J, Ironside J, Hill AF (1996). Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD.. Nature, 383(6602), 685 - 690. doi:10.1038/383685a0
    • Collinge J, Rossor M (1996). A new variant of prion disease.. Lancet, 347(9006), 916 - 917.

    1995

    • ASHWORTH A, BROWN J, GYDESEN S, SORENSEN A, ROSSOR MN, HARDY J, PALMER MS, COLLINGE J (1995). A LOCUS FOR FAMILIAL NON SPECIFIC DEMENTIA MAPS TO CHROMOSOME-3. AM J HUM GENET, 57(4), 1063 - 1063.
    • CLARK RF, HUTTON M, FULDNER RA, FROELICH S, KARRAN E, TALBOT C, CROOK R, LENDON C, PRIHAR G, HE C, KORENBLAT K, MARTINEZ A, WRAGG M, BUSFIELD F, BEHRENS MI, MYERS A, NORTON J, MORRIS J, MEHTA N, PEARSON C, LINCOLN S, BAKER M, DUFF K, ZEHR C, PEREZTUR J, HOULDEN H, RUIZ A, OSSA J, LOPERA F, ARCOS M, MADRIGAL L, COLLINGE J, HUMPHREYS C, ASHWORTH A, SARNER S, FOX N, HARVEY R, KENNEDY A, ROQUES P, CLINE RT, PHILLIPS CA, VENTER JC, FORSELL L, AXELMAN K, LILIUS L, JOHNSTON J, COWBURN R, VIITANEN M, WINBLAD B, KOSIK K, HALTIA M, POYHONEN M, DICKSON D, MANN D, NEARY D, SNOWDEN J, LANTOS P, LANNFELT L, ROSSOR M, ROBERTS GW, ADAMS MD, HARDY J, GOATE A (1995). THE STRUCTURE OF THE PRESENILIN-1 (S182) GENE AND IDENTIFICATION OF 6 NOVEL MUTATIONS IN EARLY-ONSET AD FAMILIES. NAT GENET, 11(2), 219 - 222.
    • Brown J, Ashworth A, Gydesen S, Sorensen A, Rossor M, Hardy J, Collinge J (1995). Familial non-specific dementia maps to chromosome 3.. Hum Mol Genet, 4(9), 1625 - 1628.
    • Collinge J, Palmer MS, Sidle KC, Gowland I, Medori R, Ironside J, Lantos P (1995). Transmission of fatal familial insomnia to laboratory animals.. Lancet, 346(8974), 569 - 570.
    • YULUG IG, KATSANIS N, DEBELLEROCHE J, COLLINGE J, FISHER EMC (1995). AN IMPROVED PROTOCOL FOR THE ANALYSIS OF SOD1 GENE-MUTATIONS, AND A NEW MUTATION IN EXON-4 (VOL 4, PG 1101, 1995). HUM MOL GENET, 4(8), 1474 - 1474.
    • Houlden H, Crook R, Duff K, Hutton M, Collinge J, Roques P, Rossor M, Hardy J (1995). Apolipoprotein E alleles but neither apolipoprotein B nor apolipoprotein AI/CIII alleles are associated with late onset, familial Alzheimer's disease.. Neurosci Lett, 188(3), 202 - 204.
    • MULLAN M, BENNETT C, FIGUEREDO C, HUGHES D, MANT R, OWEN M, WARREN A, MCINNIS M, MARSHALL A, LANTOS P, COLLINGE J, GOATE A, HOULDEN H, CRAWFORD F (1995). CLINICAL-FEATURES OF EARLY-ONSET, FAMILIAL ALZHEIMERS-DISEASE LINKED TO CHROMOSOME-14. AM J MED GENET, 60(1), 44 - 52.
    • Budka H, Aguzzi A, Brown P, Brucher JM, Bugiani O, Collinge J, Diringer H, Gullotta F, Haltia M, Hauw JJ (1995). Tissue handling in suspected Creutzfeldt-Jakob disease (CJD) and other human spongiform encephalopathies (prion diseases). Brain Pathol, 5(3), 319 - 322.
    • Yulug IG, Katsanis N, de Belleroche J, Collinge J, Fisher EM (1995). An improved protocol for the analysis of SOD1 gene mutations, and a new mutation in exon 4.. Hum Mol Genet, 4(6), 1101 - 1104.
    • WHITTINGTON MA, SIDLE KCL, GOWLAND I, MEADS J, HILL AF, PALMER MS, JEFFERYS JGR, COLLINGE J (1995). RESCUE OF NEUROPHYSIOLOGICAL PHENOTYPE SEEN IN PRP NULL MICE BY TRANSGENE ENCODING HUMAN PRION PROTEIN, (VOL 9, PG 197, 1995). NAT GENET, 9(4), 451 - 451.
    • Whittington MA, Sidle KC, Gowland I, Meads J, Hill AF, Palmer MS, Jefferys JG, Collinge J (1995). Rescue of neurophysiological phenotype seen in PrP null mice by transgene encoding human prion protein.. Nat Genet, 9(2), 197 - 201. doi:10.1038/ng0295-197
    • Smith C, Collinge J (1995). Molecular pathology of prion diseases.. Essays Biochem, 29, 157 - 174.
    • Collinge J (1995). Molecular genetics of human prion disease and the development of transgenic models. In Prusiner SB (Ed.), Current topics in microbiology and immunology (pp. 35 - 36). : Scientific Publishing Services (P) Ltd.
    • Collinge J, Palmer MS, Sidle KC, Hill AF, Gowland I, Meads J, Asante E, Bradley R, Doey LJ, Lantos PL (1995). Unaltered susceptibility to BSE in transgenic mice expressing human prion protein.. Nature, 378(6559), 779 - 783. doi:10.1038/378779a0
    • Britton TC, al-Sarraj S, Shaw C, Campbell T, Collinge J (1995). Sporadic Creutzfeldt-Jakob disease in a 16-year-old in the UK.. Lancet, 346(8983), 1155 - .
    • Bateman D, Hilton D, Love S, Zeidler M, Beck J, Collinge J (1995). Sporadic Creutzfeldt-Jakob disease in a 18-year-old in the UK.. Lancet, 346(8983), 1155 - 1156.
    • Ashworth A, Brown J, Gydesen S, Sorensen SA, Rossor MN, Hardy J, Collinge J (1995). Frontal lobe or 'nonspecific' dementias are genetically heterogeneous.. Neurology, 45(9), 1781 - .

    1994

    • Houlden H, Crook R, Hardy J, Roques P, Collinge J, Rossor M (1994). Confirmation that familial clustering and age of onset in late onset Alzheimer's disease are determined at the apolipoprotein E locus.. Neurosci Lett, 174(2), 222 - 224.
    • Collinge J, Palmer MS, Sidle KC, Mahal SP, Campbell T, Brown J, Hardy J, Brun AE, Gustafson L, Bakker E (1994). Familial Pick's disease and dementia in frontal lobe degeneration of non-Alzheimer type are not variants of prion disease.. J Neurol Neurosurg Psychiatry, 57(6), 762 - .
    • Collinge J, Palmer MS (1994). Human prion diseases. In Harding AE (Ed.), Genetics in Neurology (pp. 241 - 257). : Bailliere Tindall.
    • Collinge J, Palmer MS (1994). Molecular genetics of human prion diseases.. Philos Trans R Soc Lond B Biol Sci, 343(1306), 371 - 378. doi:10.1098/rstb.1994.0031
    • Collinge J, Whittington MA, Sidle KC, Smith CJ, Palmer MS, Clarke AR, Jefferys JG (1994). Prion protein is necessary for normal synaptic function.. Nature, 370(6487), 295 - 297. doi:10.1038/370295a0
    • Collinge J, Palmer MS (1994). Prion diseases. In Burns A, Levy R (Ed.), Dementia (pp. 835 - 853). : Chapman and Hall.
    • Telling GC, Scott M, Hsiao KK, Foster D, Yang SL, Torchia M, Sidle KC, Collinge J, DeArmond SJ, Prusiner SB (1994). Transmission of Creutzfeldt-Jakob disease from humans to transgenic mice expressing chimeric human-mouse prion protein.. Proc Natl Acad Sci U S A, 91(21), 9936 - 9940.
    • Ashworth A, Campbell T, Palmer M, Collinge J, Brown J (1994). G/T polymorphism in CRYA2 gene.. Hum Mol Genet, 3(9), 1712 - .
    • Collinge J, Palmer MS (1994). Human prion diseases.. Baillieres Clin Neurol, 3(2), 241 - 247.
    • COLLINGE J (1994). MOLECULAR-BIOLOGY OF PRION DISEASES - PREFACE. PHILOS T ROY SOC B, 343(1306), 353 - 353.

    1993

    • HOULDEN H, CROOK R, DUFF K, COLLINGE J, ROQUES P, ROSSOR M, HARDY J (1993). CONFIRMATION THAT THE APOLIPOPROTEIN E4 ALLELE IS ASSOCIATED WITH LATE-ONSET, FAMILIAL ALZHEIMERS-DISEASE. NEURODEGENERATION, 2(4), 283 - 286.
    • HARDY J, HOULDEN H, COLLINGE J, KENNEDY A, NEWMAN S, ROSSOR M, LANNFELT L, LILIUS L, WINBLAD B, CROOK R, DUFF K (1993). APOLIPOPROTEIN-E GENOTYPE AND ALZHEIMERS-DISEASE. LANCET, 342(8873), 737 - 738.
    • Brown J, Gydesen S, Sorensen SA, Brun A, Smith S, Houlden H, Twells R, Mullan M, Rossor M, Collinge J (1993). Genetic characterization of a familial non-specific dementia originating in Jutland, Denmark.. J Neurol Sci, 114(2), 138 - 143.
    • Collinge J, Palmer MS, Campbell T, Sidle KC, Carroll D, Harding A (1993). Inherited prion disease (PrP lysine 200) in Britain: two case reports.. BMJ, 306(6873), 301 - 302.
    • Weber T, Tumani H, Holdorff B, Collinge J, Palmer M, Kretzschmar HA, Felgenhauer K (1993). Transmission of Creutzfeldt-Jakob disease by handling of dura mater.. Lancet, 341(8837), 123 - 124.
    • Collinge J (1993). Inherited prion diseases. In Harding AE (Ed.), Advances in neurology: inherited ataxias (pp. 155 - 165). : Raven Press.
    • Collinge J, Palmer MS (1993). Prion diseases in humans and their relevance to other neurodegenerative diseases.. Dementia, 4(3-4), 178 - 185.
    • Collinge J, Palmer MS, Rossor MN, Janota I, Lantos PL (1993). Prion dementia.. Lancet, 341(8845), 627 - .
    • Palmer MS, Collinge J (1993). Mutations and polymorphisms in the prion protein gene.. Hum Mutat, 2(3), 168 - 173. doi:10.1002/humu.1380020303
    • Collinge J (1993). Inherited prion diseases.. Adv Neurol, 61, 155 - 165.
    • Palmer MS, Mahal SP, Campbell TA, Hill AF, Sidle KC, Laplanche JL, Collinge J (1993). Deletions in the prion protein gene are not associated with CJD.. Hum Mol Genet, 2(5), 541 - 544.

    1992

    • Lantos PL, McGill IS, Janota I, Doey LJ, Collinge J, Bruce MT, Whatley SA, Anderton BH, Clinton J, Roberts GW (1992). Prion protein immunocytochemistry helps to establish the true incidence of prion diseases.. Neurosci Lett, 147(1), 67 - 71.
    • Palmer MS, Collinge J (1992). Human prion diseases. In Rossor M (Ed.), Unusual dementias (pp. 627 - 651). : Bailliere Tindall.
    • Poulter M, Baker HF, Frith CD, Leach M, Lofthouse R, Ridley RM, Shah T, Owen F, Collinge J, Brown J (1992). Inherited prion disease with 144 base pair gene insertion. 1. Genealogical and molecular studies.. Brain, 115 ( Pt 3), 675 - 685.
    • Collinge J, Brown J, Hardy J, Mullan M, Rossor MN, Baker H, Crow TJ, Lofthouse R, Poulter M, Ridley R (1992). Inherited prion disease with 144 base pair gene insertion. 2. Clinical and pathological features.. Brain, 115 ( Pt 3), 687 - 710.
    • Collinge J, Palmer MS (1992). Prion diseases.. Curr Opin Genet Dev, 2(3), 448 - 454.
    • Palmer MS, Collinge J (1992). Human prion diseases.. Curr Opin Neurol Neurosurg, 5(6), 895 - 901.
    • Owen F, Poulter M, Collinge J, Leach M, Lofthouse R, Crow TJ, Harding AE (1992). A dementing illness associated with a novel insertion in the prion protein gene.. Brain Res Mol Brain Res, 13(1-2), 155 - 157.
    • COLLINGE J, PALMER MS (1992). MOLECULAR-GENETICS OF INHERITED, SPORADIC AND IATROGENIC PRION DISEASE.
    • ANDERTON B, COLLINGE J, POWELL J, PRUSINER SB (1992). AN INTRODUCTION TO PRION RESEARCH.
    • COLLINGE J, PRUSINER SB (1992). TERMINOLOGY OF PRION DISEASES.
    • COLLINGE J, PRUSINER SB (1992). PRIONS AND NEURODEGENERATIVE DISEASES.
    • Anderton BH, Collinge J, Powell J, Prusiner SB (1992). An introduction to prion research. In Prusiner SB, Collinge J, Powell J, Anderton B (Ed.), Prion diseases of humans and animals (pp. 3 - 4). : Ellis Horwood.
    • Crow TJ, Poulter M, Baker HF, Frith CD, Leach M, Lofthouse R, Ridley RM, Shah T, Owen F, Collinge J, Brown G, Hardy J, Mullan MJ, Harding AE, Bennett C, Doshi R (1992). Familial dementia in relation to the 144bp insert and its implications. In Prusiner SB, Collinge J, Powell J, Anderton B (Ed.), Prion diseases of humans & animals (pp. 200 - 214). : Ellis Horwood.
    • CROW TJ, POULTER M, BAKER HF, FRITH CD, LEACH M, LOFTHOUSE R, RIDLEY RM, SHAH T, OWEN F, COLLINGE J, BROWN G, HARDY J, MULLAN MJ, HARDING AE, BENNETT C, DOSHI R (1992). FAMILIAL DEMENTIA IN RELATION TO THE 144 BP INSERT AND ITS IMPLICATIONS.
    • Collinge J, Prusiner SB (1992). Terminology of prion disease. In Prusiner SB, Collinge J, Powell J, Anderton B (Ed.), Prion diseases of humans & animals (pp. 5 - 12). : Ellis Horwood.
    • Collinge J, Palmer S (1992). Molecular genetics of inherited, sporadic and iatrogenic prion disease. In Prusiner SB, Collinge J, Powell J, Anderton B (Ed.), Prion diseases of humans and animals (pp. 95 - 119). : Ellis Horwood.
    • Prusiner SB, Collinge J (1992). Prions and neurodegenerative diseases. In Prusiner SB, Collinge J, Powell J, Anderton B (Ed.), Prion diseases of humans & animals (pp. 568 - 569). : Ellis Horwood.
    • Palmer MS, Collinge J (1992). Human prion diseases.. Baillieres Clin Neurol, 1(3), 627 - 651.

    1991

    • Walsh C, Collinge J, Crow TJ (1991). Molecular and clinical genetics in relation to psychiatric disease.. In Granville-Grossman K (Ed.), Recent Advances in Clinical Psychiatry (pp. 119 - 137). : Churchill-Livingstone.
    • Collinge J, Palmer MS, Dryden AJ (1991). Genetic predisposition to iatrogenic Creutzfeldt-Jakob disease.. Lancet, 337(8755), 1441 - 1442.
    • Collinge J, Poulter M, Davis MB, Baraitser M, Owen F, Crow TJ, Harding AE (1991). Presymptomatic detection or exclusion of prion protein gene defects in families with inherited prion diseases.. Am J Hum Genet, 49(6), 1351 - 1354.
    • Collinge J, Curtis D (1991). Decreased hippocampal expression of a glutamate receptor gene in schizophrenia.. Br J Psychiatry, 159, 857 - 859.
    • BAKER HF, POULTER M, CROW TJ, FRITH CD, LOFTHOUSE R, RIDLEY RM, COLLINGE J (1991). AMINO-ACID POLYMORPHISM IN HUMAN PRION PROTEIN AND AGE AT DEATH IN INHERITED PRION DISEASE. LANCET, 337(8752), 1286 - 1286.
    • Owen F, Poulter M, Collinge J, Leach M, Shah T, Lofthouse R, Chen YF, Crow TJ, Harding AE, Hardy J (1991). Insertions in the prion protein gene in atypical dementias.. Exp Neurol, 112(2), 240 - 242.
    • Collinge J, Delisi LE, Boccio A, Johnstone EC, Lane A, Larkin C, Leach M, Lofthouse R, Owen F, Poulter M (1991). Evidence for a pseudo-autosomal locus for schizophrenia using the method of affected sibling pairs.. Br J Psychiatry, 158, 624 - 629.
    • Brown J, Smith S, Brun A, Collinge J, Gydesen S, Hardy J, Mullan M, Goate A (1991). Genetic characterization of a novel familial dementia.. Ann N Y Acad Sci, 640, 181 - 183.
    • RIDLEY RM, BAKER HF, POULTER M, LOFTHOUSE R, OWEN F, COLLINGE J, CROW TJ (1991). GENETICS OF HUMAN TRANSMISSIBLE DEMENTIA.
    • COLLINGE J (1991). PRION DISEASE - REDEFINING THE PHENOTYPE.
    • Collinge J (1991). Prion disease: redefining the phenotype. In Bradley R, Savey M, Marchant B (Ed.), Sub-acute spongiform encephalopathies (pp. 225 - 231). : Dordrecht: Kluwer.
    • BROWN J, SMITH S, BRUN A, COLLINGE J, GYDESEN S, HARDY J, MULLAN M, GOATE A (1991). GENETIC-CHARACTERIZATION OF A NOVEL FAMILIAL DEMENTIA. ANN NY ACAD SCI, 640, 181 - 183.
    • Roberts GW, Collinge J (1991). Playing clue with prion disease.. Lab Invest, 65(6), 607 - 609.
    • COLLINGE J, PALMER M (1991). CJD DISCREPANCY - REPLY. NATURE, 353(6347), 802 - 802.
    • COLLINGE J (1991). SPONGIFORM ENCEPHALOPATHIES - REPLY. NEUROPATH APPL NEURO, 17(4), 346 - 346.
    • Palmer MS, Dryden AJ, Hughes JT, Collinge J (1991). Homozygous prion protein genotype predisposes to sporadic Creutzfeldt-Jakob disease.. Nature, 352(6333), 340 - 342. doi:10.1038/352340a0
    • Ridley RM, Baker HF, Poulter M, Lofthouse R, Collinge J, Crow TJ (1991). Genetics of human transmissible dementia. In Bradley R, Savey M, Marchant B (Ed.), Sub-acute spongiform encephalopathies (pp. 203 - 218). : Dordrecht: Kluwer.

    1990

    • Collinge J, Owen F, Poulter M, Leach M, Crow TJ, Rossor MN, Hardy J, Mullan MJ, Janota I, Lantos PL (1990). Prion dementia without characteristic pathology.. Lancet, 336(8706), 7 - 9.
    • Owen F, Poulter M, Collinge J, Crow TJ (1990). Codon 129 changes in the prion protein gene in Caucasians.. Am J Hum Genet, 46(6), 1215 - 1216.
    • Owen F, Poulter M, Shah T, Collinge J, Lofthouse R, Baker H, Ridley R, McVey J, Crow TJ (1990). An in-frame insertion in the prion protein gene in familial Creutzfeldt-Jakob disease.. Brain Res Mol Brain Res, 7(3), 273 - 276.
    • COLLINGE J, OWEN F, POULTER M, HARDING AE, ROSSOR M, MULLEN M, LEACH M, CROW TJ (1990). PRION PROTEIN GENE ANALYSIS IN PRESENILE DEMENTING AND ATAXIC ILLNESSES. NEUROBIOL AGING, 11(3), 321 - 321.
    • ROBERTS GW, COLLINGE J (1990). BOVINE SPONGIFORM ENCEPHALOPATHY. BRIT MED J, 300(6729), 943 - 943.
    • OWEN F, POULTER M, COLLINGE J, CROW TJ (1990). A CODON 129 POLYMORPHISM IN THE PRIP GENE. NUCLEIC ACIDS RES, 18(10), 3103 - 3103.

    1989

    • Owen F, Poulter M, Lofthouse R, Collinge J, Crow TJ, Risby D, Baker HF, Ridley RM, Hsiao K, Prusiner SB (1989). Insertion in prion protein gene in familial Creutzfeldt-Jakob disease.. Lancet, 1(8628), 51 - 52.
    • Collinge J, Harding AE, Owen F, Poulter M, Lofthouse R, Boughey AM, Shah T, Crow TJ (1989). Diagnosis of Gerstmann-Sträussler syndrome in familial dementia with prion protein gene analysis.. Lancet, 2(8653), 15 - 17.
    • COLLINGE J, BOCCIO A, DELISI L, JOHNSTONE E, LOFTHOUSE R, OWEN F, POULTER M, RISBY D, SHAH T, TJ C (1989). Evidence for a pseudoautosomal locus for schizophrenia. Cytogenet Cell Genet, 51(1-4), 978 - 978.

    1987

    • Collinge J, Roberts CJ (1987). Study of the action of cicletanine in hyperuricemic patients.. J Clin Pharmacol, 27(10), 802 - 806.

    1983

    • Collinge J, Pycock CJ, Taberner PV (1983). Studies on the interaction between cerebral 5-hydroxytryptamine and gamma-aminobutyric acid in the mode of action of diazepam in the rat.. Br J Pharmacol, 79(3), 637 - 643.

    1982

    • Collinge J, Pycock C (1982). Differential actions of diazepam on the release of [3H]5-hydroxytryptamine from cortical and midbrain raphe slices in the rat.. Eur J Pharmacol, 85(1), 9 - 14.

    • Rossi M, Mead S, Collinge J, Rudge P, Vincent A (). Neuronal antibodies in patients with suspected or confirmed sporadic Creutzfeldt-Jakob Disease. Journal of Neurology, Neurosurgery, and Psychiatry, , - .