Dr Andrew Mcquillin

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Personal Profile

Name: Andrew Mcquillin Email: a.mcquillin@ucl.ac.uk
Title: Dr Tel: 020 3108 2188
Department: Division of Psychiatry Fax: 020 3108 2194
Position: Senior Lecturer Address: Rockefeller Building, Gower Street, London, WC1E 6BT
Research Domain: Genetics (Frontier Disciplines), Neuroscience Web Page: Personal Web Page

Profile

Research Description

Research in the Molecular Psychiatry laboratory has centred on the use of genetics to develop an understanding of the abnormal neurobiology that increases the risk of developing schizophrenia, bipolar disorder, ADHD and alcoholism.
We have contributed to large scale international multi centre genome wide association studies of schizophrenia, bipolar disorder and Alzheimer's dementia. These studies have implicated a number of genes in the different disorders. Genome wide association scans are planned on a second sample of bipolar cases and also in a large alcohol dependence syndrome sample. Genetic effects in susceptibility to Wernicke Korsakov's syndrome and alcoholic cirrhosis of the liver are also being investigated. We are also interested in the overlap between genes that increase susceptibility to bipolar disorder and alcoholism.


Research Activities

Genetics and Neurobiology of Mental Illness

Molecular genetics

Education Description

I am co-director of the new MRes in Brain Sciences course that will start in the 2013 academic year. For more information please visit see the course website www.ucl.ac.uk/mresbrainsciences.

I teach Biological Psychiatry and Bioinformatics on the MSc in Psychiatric Research and supervise MSc project students on the MSc in the Genetics of Human Disease.

UCL Collaborators

Prof Andres Ruiz-Linares; Prof Michelle Saunders; Dr Clare Stanford; Prof Marsha Morgan; Prof Steve Hunt

External Collaborators

Publications

    2014

    • Morris DW, Pearson RD, Cormican P, Kenny EM, O'Dushlaine CT, Lemieux Perreault LP, Giannoulatou E, Tropea D, Maher BS, Wormley B, Kelleher E, Fahey C, Molinos I, Bellini S, Pirinen M, Strange A, Freeman C, Thiselton DL, Elves RL, Regan R, Ennis S, Dinan TG, McDonald C, Murphy KC, O'Callaghan E, Waddington JL, Walsh D, O'Donovan M, Grozeva D, Craddock N, Stone J, Scolnick E, Purcell S, Sklar P, Coe B, Eichler EE, Ophoff R, Buizer J, Szatkiewicz J, Hultman C, Sullivan P, Gurling H, McQuillin A, St Clair D, Rees E, Kirov G, Walters J, Blackwood D, Johnstone M, Donohoe G, International Schizophrenia Consortium , SGENE+ Consortium , O'Neill FA, Wellcome Trust Case Control Consortium 2 , Kendler KS, Gill M, Riley BP, Spencer CC, Corvin A (2014). An inherited duplication at the gene p21 Protein-Activated Kinase 7 (PAK7) is a risk factor for psychosis.. Hum Mol Genet, , - . doi:10.1093/hmg/ddu025
    • Xu W, Cohen-Woods S, Chen Q, Noor A, Knight J, Hosang G, Parikh SV, De Luca V, Tozzi F, Muglia P, Forte J, McQuillin A, Hu P, Gurling HM, Kennedy JL, McGuffin P, Farmer A, Strauss J, Vincent JB (2014). Genome-wide association study of bipolar disorder in Canadian and UK populations corroborates disease loci including SYNE1 and CSMD1.. BMC Med Genet, 15(1), 2 - . doi:10.1186/1471-2350-15-2

    2013

    • Anstee QM, Knapp S, Maguire EP, Hosie AM, Thomas P, Mortensen M, Bhome R, Martinez A, Walker SE, Dixon CI, Ruparelia K, Montagnese S, Kuo YT, Herlihy A, Bell JD, Robinson I, Guerrini I, McQuillin A, Fisher EM, Ungless MA, Gurling HM, Morgan MY, Brown SD, Stephens DN, Belelli D, Lambert JJ, Smart TG, Thomas HC (2013). Mutations in the Gabrb1 gene promote alcohol consumption through increased tonic inhibition.. Nat Commun, 4, 2816 - . doi:10.1038/ncomms3816
    • Cross-Disorder Group of the Psychiatric Genomics Consortium , Lee SH, Ripke S, Neale BM, Faraone SV, Purcell SM, Perlis RH, Mowry BJ, Thapar A, Goddard ME, Witte JS, Absher D, Agartz I, Akil H, Amin F, Andreassen OA, Anjorin A, Anney R, Anttila V, Arking DE, Asherson P, Azevedo MH, Backlund L, Badner JA, Bailey AJ, Banaschewski T, Barchas JD, Barnes MR, Barrett TB, Bass N, Battaglia A, Bauer M, Bayés M, Bellivier F, Bergen SE, Berrettini W, Betancur C, Bettecken T, Biederman J, Binder EB, Black DW, Blackwood DH, Bloss CS, Boehnke M, Boomsma DI, Breen G, Breuer R, Bruggeman R, Cormican P, Buccola NG, Buitelaar JK, Bunney WE, Buxbaum JD, Byerley WF, Byrne EM, Caesar S, Cahn W, Cantor RM, Casas M, Chakravarti A, Chambert K, Choudhury K, Cichon S, Cloninger CR, Collier DA, Cook EH, Coon H, Cormand B, Corvin A, Coryell WH, Craig DW, Craig IW, Crosbie J, Cuccaro ML, Curtis D, Czamara D, Datta S, Dawson G, Day R, De Geus EJ, Degenhardt F, Djurovic S, Donohoe GJ, Doyle AE, Duan J, Dudbridge F, Duketis E, Ebstein RP, Edenberg HJ, Elia J, Ennis S, Etain B, Fanous A, Farmer AE, Ferrier IN, Flickinger M, Fombonne E, Foroud T, Frank J, Franke B, Fraser C, Freedman R, Freimer NB, Freitag CM, Friedl M, Frisén L, Gallagher L, Gejman PV, Georgieva L, Gershon ES, Geschwind DH, Giegling I, Gill M, Gordon SD, Gordon-Smith K, Green EK, Greenwood TA, Grice DE, Gross M, Grozeva D, Guan W, Gurling H, De Haan L, Haines JL, Hakonarson H, Hallmayer J, Hamilton SP, Hamshere ML, Hansen TF, Hartmann AM, Hautzinger M, Heath AC, Henders AK, Herms S, Hickie IB, Hipolito M, Hoefels S, Holmans PA, Holsboer F, Hoogendijk WJ, Hottenga JJ, Hultman CM, Hus V, Ingason A, Ising M, Jamain S, Jones EG, Jones I, Jones L, Tzeng JY, Kähler AK, Kahn RS, Kandaswamy R, Keller MC, Kennedy JL, Kenny E, Kent L, Kim Y, Kirov GK, Klauck SM, Klei L, Knowles JA, Kohli MA, Koller DL, Konte B, Korszun A, Krabbendam L, Krasucki R, Kuntsi J, Kwan P, Landén M, Långström N, Lathrop M, Lawrence J, Lawson WB, Leboyer M, Ledbetter DH, Lee PH, Lencz T, Lesch KP, Levinson DF, Lewis CM, Li J, Lichtenstein P, Lieberman JA, Lin DY, Linszen DH, Liu C, Lohoff FW, Loo SK, Lord C, Lowe JK, Lucae S, Macintyre DJ, Madden PA, Maestrini E, Magnusson PK, Mahon PB, Maier W, Malhotra AK, Mane SM, Martin CL, Martin NG, Mattheisen M, Matthews K, Mattingsdal M, McCarroll SA, McGhee KA, McGough JJ, McGrath PJ, McGuffin P, McInnis MG, McIntosh A, McKinney R, McLean AW, McMahon FJ, McMahon WM, McQuillin A, Medeiros H, Medland SE, Meier S, Melle I, Meng F, Meyer J, Middeldorp CM, Middleton L, Milanova V, Miranda A, Monaco AP, Montgomery GW, Moran JL, Moreno-De-Luca D, Morken G, Morris DW, Morrow EM, Moskvina V, Muglia P, Mühleisen TW, Muir WJ, Müller-Myhsok B, Murtha M, Myers RM, Myin-Germeys I, Neale MC, Nelson SF, Nievergelt CM, Nikolov I, Nimgaonkar V, Nolen WA, Nöthen MM, Nurnberger JI, Nwulia EA, Nyholt DR, O'Dushlaine C, Oades RD, Olincy A, Oliveira G, Olsen L, Ophoff RA, Osby U, Owen MJ, Palotie A, Parr JR, Paterson AD, Pato CN, Pato MT, Penninx BW, Pergadia ML, Pericak-Vance MA, Pickard BS, Pimm J, Piven J, Posthuma D, Potash JB, Poustka F, Propping P, Puri V, Quested DJ, Quinn EM, Ramos-Quiroga JA, Rasmussen HB, Raychaudhuri S, Rehnström K, Reif A, Ribasés M, Rice JP, Rietschel M, Roeder K, Roeyers H, Rossin L, Rothenberger A, Rouleau G, Ruderfer D, Rujescu D, Sanders AR, Sanders SJ, Santangelo SL, Sergeant JA, Schachar R, Schalling M, Schatzberg AF, Scheftner WA, Schellenberg GD, Scherer SW, Schork NJ, Schulze TG, Schumacher J, Schwarz M, Scolnick E, Scott LJ, Shi J, Shilling PD, Shyn SI, Silverman JM, Slager SL, Smalley SL, Smit JH, Smith EN, Sonuga-Barke EJ, St Clair D, State M, Steffens M, Steinhausen HC, Strauss JS, Strohmaier J, Stroup TS, Sutcliffe JS, Szatmari P, Szelinger S, Thirumalai S, Thompson RC, Todorov AA, Tozzi F, Treutlein (2013). Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs.. Nat Genet, , - . doi:10.1038/ng.2711
    • Sharp SI, Hu Y, Weymer JF, Rizig M, McQuillin A, Hunt SP, Gurling HM (2013). The effect of clozapine on mRNA expression for genes encoding G protein-coupled receptors and the protein components of clathrin-mediated endocytosis.. Psychiatr Genet, 23(4), 153 - 162. doi:10.1097/YPG.0b013e32835fe51d
    • Way MJ, McQuillin AS, Gurling HM, Morgan MY (2013). THE ZNF699 GENE IS NOT ASSOCIATED WITH ALCOHOL DEPENDENCE IN A UK SAMPLE BUT MAY ALTER RISK FOR ALCOHOL-RELATED CIRRHOSIS.
    • Kandaswamy R, McQuillin A, Sharp SI, Fiorentino A, Anjorin A, Blizard RA, Curtis D, Gurling HM (2013). Genetic association, mutation screening, and functional analysis of a Kozak sequence variant in the metabotropic glutamate receptor 3 gene in bipolar disorder.. JAMA Psychiatry, 70(6), 591 - 598. doi:10.1001/jamapsychiatry.2013.38
    • Ruderfer DM, Fanous AH, Ripke S, McQuillin A, Amdur RL, Schizophrenia Working Group of the Psychiatric Genomics Consortium , Bipolar Disorder Working Group of the Psychiatric Genomics Consortium , Cross-Disorder Working Group of the Psychiatric Genomics Consortium , Gejman PV, O'Donovan MC, Andreassen OA, Djurovic S, Hultman CM, Kelsoe JR, Jamain S, Landén M, Leboyer M, Nimgaonkar V, Nurnberger J, Smoller JW, Craddock N, Corvin A, Sullivan PF, Holmans P, Sklar P, Kendler KS (2013). Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia.. Mol Psychiatry, , - . doi:10.1038/mp.2013.138
    • Way MJ, McQuillin A, Gurling HMD, Morgan MY (2013). THE PNPA3 I148M MUTATION SIGNIFICANTLY INCREASES THE RISK OF DEVELOPING ALCOHOL-RELATED CIRRHOSIS IN ALCOHOL DEPENDENT INDIVIDUALS.
    • Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Williams A, Jones N, Thomas C, Stretton A, Morgan AR, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Morgan K, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Holmes C, Mann D, Smith AD, Love S, Kehoe PG, Hardy J, Mead S, Fox N, Rossor M, Collinge J, Maier W, Jessen F, Schürmann B, Heun R, van den Bussche H, Heuser I, Kornhuber J, Wiltfang J, Dichgans M, Frölich L, Hampel H, Hüll M, Rujescu D, Goate AM, Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Sleegers K, Bettens K, Engelborghs S, De Deyn PP, Van Broeckhoven C, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Tsolaki M, Singleton AB, Guerreiro R, Mühleisen TW, Nöthen MM, Moebus S, Jöckel KH, Klopp N, Wichmann HE, Carrasquillo MM, Pankratz VS, Younkin SG, Holmans PA, O'Donovan M, Owen MJ, Williams J (2013). Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.. Nat Genet, 45(6), 712 - . doi:10.1038/ng0613-712a

    2012

    • Gerrish A, Russo G, Richards A, Moskvina V, Ivanov D, Harold D, Sims R, Abraham R, Hollingworth P, Chapman J, Hamshere M, Pahwa JS, Dowzell K, Williams A, Jones N, Thomas C, Stretton A, Morgan AR, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Morgan K, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Johnston JA, Holmes C, Mann D, Smith AD, Love S, Kehoe PG, Hardy J, Mead S, Fox N, Rossor M, Collinge J, Maier W, Jessen F, Kölsch H, Heun R, Schürmann B, van den Bussche H, Heuser I, Kornhuber J, Wiltfang J, Dichgans M, Frölich L, Hampel H, Hüll M, Rujescu D, Goate AM, Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Davies G, Harris SE, Starr JM, Deary IJ, Al-Chalabi A, Shaw CE, Tsolaki M, Singleton AB, Guerreiro R, Mühleisen TW, Nöthen MM, Moebus S, Jöckel KH, Klopp N, Wichmann HE, Carrasquillo MM, Pankratz VS, Younkin SG, Jones L, Holmans PA, O'Donovan MC, Owen MJ, Williams J (2012). The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease.. J Alzheimers Dis, 28(2), 377 - 387. doi:10.3233/JAD-2011-110824
    • Hollingworth P, Sweet R, Sims R, Harold D, Russo G, Abraham R, Stretton A, Jones N, Gerrish A, Chapman J, Ivanov D, Moskvina V, Lovestone S, Priotsi P, Lupton M, Brayne C, Gill M, Lawlor B, Lynch A, Craig D, McGuinness B, Johnston J, Holmes C, Livingston G, Bass NJ, Gurling H, McQuillin A, GERAD Consortium , National Institute on Aging Late-Onset Alzheimer's Disease Family Study Group , Holmans P, Jones L, Devlin B, Klei L, Barmada MM, Demirci FY, DeKosky ST, Lopez OL, Passmore P, Owen MJ, O'Donovan MC, Mayeux R, Kamboh MI, Williams J (2012). Genome-wide association study of Alzheimer's disease with psychotic symptoms.. Mol Psychiatry, 17(12), 1316 - 1327. doi:10.1038/mp.2011.125
    • Szyszka P, Sharp SI, Dedman A, Gurling HM, McQuillin A (2012). A nonconservative amino acid change in the UPF3B gene in a patient with schizophrenia.. Psychiatr Genet, 22(3), 150 - 151. doi:10.1097/YPG.0b013e32834accbe
    • Kandaswamy R, McQuillin A, Curtis D, Gurling H (2012). Tests of linkage and allelic association between markers in the 1p36 PRKCZ (protein kinase C zeta) gene region and bipolar affective disorder.. Am J Med Genet B Neuropsychiatr Genet, 159B(2), 201 - 209. doi:10.1002/ajmg.b.32014
    • Rizig MA, McQuillin A, Ng A, Robinson M, Harrison A, Zvelebil M, Hunt SP, Gurling HM (2012). A gene expression and systems pathway analysis of the effects of clozapine compared to haloperidol in the mouse brain implicates susceptibility genes for schizophrenia.. J Psychopharmacol, 26(9), 1218 - 1230. doi:10.1177/0269881112450780
    • Dedman A, McQuillin A, Kandaswamy R, Sharp S, Anjorin A, Gurling H (2012). Sequencing of the ANKYRIN 3 gene (ANK3) encoding ankyrin G in bipolar disorder reveals a non-conservative amino acid change in a short isoform of ankyrin G.. Am J Med Genet B Neuropsychiatr Genet, 159B(3), 328 - 335. doi:10.1002/ajmg.b.32030
    • Rizig MA, McQuillin A, Ng A, Robinson M, Harrison A, Zvelebil M, Hunt SP, Gurling HM (2012). A gene expression and systems pathway analysis of the effects of clozapine compared to haloperidol in the mouse brain implicates susceptibility genes for schizophrenia. JOURNAL OF PSYCHOPHARMACOLOGY, 26(9), 1218 - 1230. doi:10.1177/0269881112450780

    2011

    • Rapp GE, Pineda-Trujillo N, McQuillin A, Tonetti M (2011). Genetic power of a Brazilian three-generation family with generalized aggressive periodontitis. II.. Braz Dent J, 22(1), 68 - 73.
    • Lydall GJ, Saini J, Ruparelia K, Montagnese S, McQuillin A, Guerrini I, Rao H, Reynolds G, Ball D, Smith I, Thomson AD, Morgan MY, Gurling HM (2011). Genetic association study of GABRA2 single nucleotide polymorphisms and electroencephalography in alcohol dependence.. Neurosci Lett, 500(3), 162 - 166. doi:10.1016/j.neulet.2011.05.240
    • Kasiakogia-Worlley K, McQuillin A, Lydall GJ, Patel S, Kottalgi G, Gunwardena P, Cherian R, Rao H, Hillman A, Gobikrishnan N, Douglas E, Qureshi SY, Jauhar S, Ball D, Okane A, Owens L, Dedman A, Sharp SI, Kandaswamy R, Guerrini I, Thomson AD, Smith I, Dar K, Morgan MY, Gurling HM (2011). Lack of allelic association between markers at the DRD2 and ANKK1 gene loci with the alcohol-dependence syndrome and criminal activity.. Psychiatr Genet, 21(6), 323 - 324. doi:10.1097/YPG.0b013e3283458a68
    • Jones L, Holmans PA, Hamshere ML, Harold D, Moskvina V, Ivanov D, Pocklington A, Abraham R, Hollingworth P, Sims R, Gerrish A, Pahwa JS, Jones N, Stretton A, Morgan AR, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Morgan K, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Holmes C, Mann D, Smith AD, Love S, Kehoe PG, Mead S, Fox N, Rossor M, Collinge J, Maier W, Jessen F, Schürmann B, van den Bussche H, Heuser I, Peters O, Kornhuber J, Wiltfang J, Dichgans M, Frölich L, Hampel H, Hüll M, Rujescu D, Goate AM, Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Singleton AB, Guerreiro R, Mühleisen TW, Nöthen MM, Moebus S, Jöckel KH, Klopp N, Wichmann HE, Rüther E, Carrasquillo MM, Pankratz VS, Younkin SG, Hardy J, O'Donovan MC, Owen MJ, Williams J (2011). Correction: genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease.. PLoS One, 6(2), - . doi:10.1371/annotation/a0bb886d-d345-4a20-a82e-adce9b047798
    • Pereira AC, McQuillin A, Puri V, Anjorin A, Bass N, Kandaswamy R, Lawrence J, Curtis D, Sklar P, Purcell SM, Gurling HM (2011). Genetic association and sequencing of the insulin-like growth factor 1 gene in bipolar affective disorder.. Am J Med Genet B Neuropsychiatr Genet, 156(2), 177 - 187. doi:10.1002/ajmg.b.31153
    • McQuillin A, Bass N, Anjorin A, Lawrence J, Kandaswamy R, Lydall G, Moran J, Sklar P, Purcell S, Gurling H (2011). Analysis of genetic deletions and duplications in the University College London bipolar disorder case control sample.. Eur J Hum Genet, 19(5), 588 - 592. doi:10.1038/ejhg.2010.221
    • Lydall GJ, Bass NJ, McQuillin A, Lawrence J, Anjorin A, Kandaswamy R, Pereira A, Guerrini I, Curtis D, Vine AE, Sklar P, Purcell SM, Gurling HM (2011). Confirmation of prior evidence of genetic susceptibility to alcoholism in a genome-wide association study of comorbid alcoholism and bipolar disorder.. Psychiatr Genet, 21(6), 294 - 306. doi:10.1097/YPG.0b013e32834915c2
    • Sims R, Dwyer S, Harold D, Gerrish A, Hollingworth P, Chapman J, Jones N, Abraham R, Ivanov D, Pahwa JS, Moskvina V, Dowzell K, Thomas C, Stretton A, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Morgan K, Brown KS, Passmore PA, Craig D, McGuiness B, Todd S, Johnston JA, Holmes C, Mann D, Smith AD, Love S, Kehoe PG, Hardy J, Mead S, Fox N, Rossor M, Collinge J, Livingston G, Bass NJ, Gurling H, McQuillin A, Jones L, Holmans PA, O'Donovan M, Owen MJ, Williams J (2011). No evidence that extended tracts of homozygosity are associated with Alzheimer's disease.. Am J Med Genet B Neuropsychiatr Genet, 156B(7), 764 - 771. doi:10.1002/ajmg.b.31216
    • Ingason A, Kirov G, Giegling I, Hansen T, Isles AR, Jakobsen KD, Kristinsson KT, le Roux L, Gustafsson O, Craddock N, Möller HJ, McQuillin A, Muglia P, Cichon S, Rietschel M, Ophoff RA, Djurovic S, Andreassen OA, Pietiläinen OP, Peltonen L, Dempster E, Collier DA, St Clair D, Rasmussen HB, Glenthøj BY, Kiemeney LA, Franke B, Tosato S, Bonetto C, Saemundsen E, Hreidarsson SJ, GROUP Investigators , Nöthen MM, Gurling H, O'Donovan MC, Owen MJ, Sigurdsson E, Petursson H, Stefansson H, Rujescu D, Stefansson K, Werge T (2011). Maternally derived microduplications at 15q11-q13: implication of imprinted genes in psychotic illness.. Am J Psychiatry, 168(4), 408 - 417. doi:10.1176/appi.ajp.2010.09111660
    • Curtis D, Vine AE, McQuillin A, Bass NJ, Pereira A, Kandaswamy R, Lawrence J, Anjorin A, Choudhury K, Datta SR, Puri V, Krasucki R, Pimm J, Thirumalai S, Quested D, Gurling HM (2011). Case-case genome-wide association analysis shows markers differentially associated with schizophrenia and bipolar disorder and implicates calcium channel genes.. Psychiatr Genet, 21(1), 1 - 4. doi:10.1097/YPG.0b013e3283413382
    • Chen X, Lee G, Maher BS, Fanous AH, Chen J, Zhao Z, Guo A, van den Oord E, Sullivan PF, Shi J, Levinson DF, Gejman PV, Sanders A, Duan J, Owen MJ, Craddock NJ, O'Donovan MC, Blackman J, Lewis D, Kirov GK, Qin W, Schwab S, Wildenauer D, Chowdari K, Nimgaonkar V, Straub RE, Weinberger DR, O'Neill FA, Walsh D, Bronstein M, Darvasi A, Lencz T, Malhotra AK, Rujescu D, Giegling I, Werge T, Hansen T, Ingason A, Nöethen MM, Rietschel M, Cichon S, Djurovic S, Andreassen OA, Cantor RM, Ophoff R, Corvin A, Morris DW, Gill M, Pato CN, Pato MT, Macedo A, Gurling HM, McQuillin A, Pimm J, Hultman C, Lichtenstein P, Sklar P, Purcell SM, Scolnick E, St Clair D, Blackwood DH, Kendler KS, GROUP investigators , International Schizophrenia Consortium (2011). GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia.. Mol Psychiatry, 16(11), 1117 - 1129. doi:10.1038/mp.2010.96
    • Hamshere ML, O'Donovan MC, Jones IR, Jones L, Kirov G, Green EK, Moskvina V, Grozeva D, Bass N, McQuillin A, Gurling H, St Clair D, Young AH, Ferrier IN, Farmer A, McGuffin P, Sklar P, Purcell S, Holmans PA, Owen MJ, Craddock N (2011). Polygenic dissection of the bipolar phenotype. BRIT J PSYCHIAT, 198(4), 284 - 288. doi:10.1192/bjp.bp.110.087866
    • Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium (2011). Genome-wide association study identifies five new schizophrenia loci.. Nat Genet, 43(10), 969 - 976. doi:10.1038/ng.940
    • Psychiatric GWAS Consortium Bipolar Disorder Working Group (2011). Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.. Nat Genet, 43(10), 977 - 983. doi:10.1038/ng.943
    • Hollingworth P, Harold D, Sims R, Gerrish A, Lambert JC, Carrasquillo MM, Abraham R, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Jones N, Stretton A, Thomas C, Richards A, Ivanov D, Widdowson C, Chapman J, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Holmes C, Mann D, Smith AD, Beaumont H, Warden D, Wilcock G, Love S, Kehoe PG, Hooper NM, Vardy ER, Hardy J, Mead S, Fox NC, Rossor M, Collinge J, Maier W, Jessen F, Rüther E, Schürmann B, Heun R, Kölsch H, van den Bussche H, Heuser I, Kornhuber J, Wiltfang J, Dichgans M, Frölich L, Hampel H, Gallacher J, Hüll M, Rujescu D, Giegling I, Goate AM, Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Sleegers K, Bettens K, Engelborghs S, De Deyn PP, Van Broeckhoven C, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Tsolaki M, Singleton AB, Guerreiro R, Mühleisen TW, Nöthen MM, Moebus S, Jöckel KH, Klopp N, Wichmann HE, Pankratz VS, Sando SB, Aasly JO, Barcikowska M, Wszolek ZK, Dickson DW, Graff-Radford NR, Petersen RC, Alzheimer's Disease Neuroimaging Initiative , van Duijn CM, Breteler MM, Ikram MA, DeStefano AL, Fitzpatrick AL, Lopez O, Launer LJ, Seshadri S, CHARGE consortium , Berr C, Campion D, Epelbaum J, Dartigues JF, Tzourio C, Alpérovitch A, Lathrop M, EADI1 consortium , Feulner TM, Friedrich P, Riehle C, Krawczak M, Schreiber S, Mayhaus M, Nicolhaus S, Wagenpfeil S, Steinberg S, Stefansson H, Stefansson K, Snaedal J, Björnsson S, Jonsson PV, Chouraki V, Genier-Boley B, Hiltunen M, Soininen H, Combarros O, Zelenika D, Delepine M, Bullido MJ, Pasquier F, Mateo I, Frank-Garcia A, Porcellini E, Hanon O, Coto E, Alvarez V, Bosco P, Siciliano G, Mancuso M, Panza F, Solfrizzi V, Nacmias B, Sorbi S, Bossù P, Piccardi P, Arosio B, Annoni G, Seripa D, Pilotto A, Scarpini E, Galimberti D, Brice A, Hannequin D, Licastro F, Jones L, Holmans PA, Jonsson T, Riemenschneider M, Morgan K, Younkin SG, Owen MJ, O'Donovan M, Amouyel P, Williams J (2011). Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.. Nat Genet, 43(5), 429 - 435. doi:10.1038/ng.803

    2010

    • Jones L, Holmans PA, Hamshere ML, Harold D, Moskvina V, Ivanov D, Pocklington A, Abraham R, Hollingworth P, Sims R, Gerrish A, Pahwa JS, Jones N, Stretton A, Morgan AR, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Morgan K, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Holmes C, Mann D, Smith AD, Love S, Kehoe PG, Mead S, Fox N, Rossor M, Collinge J, Maier W, Jessen F, Schürmann B, Heun R, Kölsch H, van den Bussche H, Heuser I, Peters O, Kornhuber J, Wiltfang J, Dichgans M, Frölich L, Hampel H, Hüll M, Rujescu D, Goate AM, Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Singleton AB, Guerreiro R, Mühleisen TW, Nöthen MM, Moebus S, Jöckel KH, Klopp N, Wichmann HE, Rüther E, Carrasquillo MM, Pankratz VS, Younkin SG, Hardy J, O'Donovan MC, Owen MJ, Williams J (2010). Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease.. PLoS One, 5(11), e13950 - . doi:10.1371/journal.pone.0013950
    • Nyegaard M, Severinsen JE, Als TD, Hedemand A, Straarup S, Nordentoft M, McQuillin A, Bass N, Lawrence J, Thirumalai S, Pereira AC, Kandaswamy R, Lydall GJ, Sklar P, Scolnick E, Purcell S, Curtis D, Gurling HM, Mortensen PB, Mors O, Borglum AD (2010). Support of association between BRD1 and both schizophrenia and bipolar affective disorder. Am J Med Genet B Neuropsychiatr Genet, 153B, 582 - 591. doi:10.1002/ajmg.b.31023
    • Perlis RH, Huang J, Purcell S, Fava M, Rush AJ, Sullivan PF, Hamilton SP, McMahon FJ, Schulze TG, Potash JB, Zandi PP, Willour VL, Penninx BW, Boomsma DI, Vogelzangs N, Middeldorp CM, Rietschel M, Nöthen M, Cichon S, Gurling H, Bass N, McQuillin A, Hamshere M, Wellcome Trust Case Control Consortium Bipolar Disorder Group , Craddock N, Sklar P, Smoller JW (2010). Genome-wide association study of suicide attempts in mood disorder patients.. Am J Psychiatry, 167(12), 1499 - 1507. doi:10.1176/appi.ajp.2010.10040541
    • Datta SR, McQuillin A, Rizig M, Blaveri E, Thirumalai S, Kalsi G, Lawrence J, Bass NJ, Puri V, Choudhury K, Pimm J, Crombie C, Fraser G, Walker N, Curtis D, Zvelebil M, Pereira A, Kandaswamy R, St Clair D, Gurling HM (2010). A threonine to isoleucine missense mutation in the pericentriolar material 1 gene is strongly associated with schizophrenia. Mol Psychiatry, 15, 615 - 628. doi:10.1038/mp.2008.128
    • Rapp GE, Pineda-Trujillo N, McQuillin A, Tonetti M (2010). Genetic power of a Brazilian three-generation family with generalized aggressive periodontitis.. Braz Dent J, 21(2), 137 - 141.
    • Yan TC, McQuillin A, Thapar A, Asherson P, Hunt SP, Stanford SC, Gurling H (2010). NK1 (TACR1) receptor gene 'knockout' mouse phenotype predicts genetic association with ADHD. J Psychopharmacol, 24, 27 - 38. doi:10.1177/0269881108100255
    • Lydall GJ, McQuillin A, Guerrini I, O'Kane A, Jauhar S, Patel S, Qureshi S, Gobikrishnan B, Douglas E, Hillman A, Kottalgi G, Reynolds G, Cherian R, Thomson AD, Ball D, Smith I, Rao H, Cook C, Morgan MY, Gurling HMD (2010). MAPPING OF SUSCEPTIBILITY GENES EXPLAINING THE COMORBIDITY BETWEEN THE ALCOHOL DEPENDENCE SYNDROME AND BIPOLAR AFFECTIVE DISORDER.

    2009

    • Vine AE, McQuillin A, Bass NJ, Pereira A, Kandaswamy R, Robinson M, Lawrence J, Anjorin A, Sklar P, Gurling HM, Curtis D (2009). No evidence for excess runs of homozygosity in bipolar disorder. Psychiatr Genet, 19, 165 - 170. doi:10.1097/YPG.0b013e32832a4faa
    • McQuillin A, Bass NJ, Choudhury K, Puri V, Kosmin M, Lawrence J, Curtis D, Gurling HM (2009). Case-control studies show that a non-conservative amino-acid change from a glutamine to arginine in the P2RX7 purinergic receptor protein is associated with both bipolar- and unipolar-affective disorders. Mol Psychiatry, 14, 614 - 620. doi:10.1038/mp.2008.6
    • Sharp SI, McQuillin A, Gurling HM (2009). Genetics of attention-deficit hyperactivity disorder (ADHD). Neuropharmacology, 57, 590 - 600. doi:10.1016/j.neuropharm.2009.08.011
    • Hennah W, Thomson P, McQuillin A, Bass N, Loukola A, Anjorin A, Blackwood D, Curtis D, Deary IJ, Harris SE, Isometsä ET, Lawrence J, Lönnqvist J, Muir W, Palotie A, Partonen T, Paunio T, Pylkkö E, Robinson M, Soronen P, Suominen K, Suvisaari J, Thirumalai S, St Clair D, Gurling H, Peltonen L, Porteous D (2009). DISC1 association, heterogeneity and interplay in schizophrenia and bipolar disorder.. Mol Psychiatry, 14(9), 865 - 873. doi:10.1038/mp.2008.22
    • Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Williams A, Jones N, Thomas C, Stretton A, Morgan AR, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Morgan K, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Holmes C, Mann D, Smith AD, Love S, Kehoe PG, Hardy J, Mead S, Fox N, Rossor M, Collinge J, Maier W, Jessen F, Schurmann B, van den Bussche H, Heuser I, Kornhuber J, Wiltfang J, Dichgans M, Frolich L, Hampel H, Hull M, Rujescu D, Goate AM, Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Sleegers K, Bettens K, Engelborghs S, De Deyn PP, Van Broeckhoven C, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Tsolaki M, Singleton AB, Guerreiro R, Muhleisen TW, Nothen MM, Moebus S, Jockel KH, Klopp N, Wichmann HE, Carrasquillo MM, Pankratz VS, Younkin SG, Holmans PA, O'Donovan M, Owen MJ, Williams J (2009). Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat Genet, 41, 1088 - 1093. doi:10.1038/ng.440
    • Ng MY, Levinson DF, Faraone SV, Suarez BK, DeLisi LE, Arinami T, Riley B, Paunio T, Pulver AE, Irmansyah , Holmans PA, Escamilla M, Wildenauer DB, Williams NM, Laurent C, Mowry BJ, Brzustowicz LM, Maziade M, Sklar P, Garver DL, Abecasis GR, Lerer B, Fallin MD, Gurling HM, Gejman PV, Lindholm E, Moises HW, Byerley W, Wijsman EM, Forabosco P, Tsuang MT, Hwu HG, Okazaki Y, Kendler KS, Wormley B, Fanous A, Walsh D, O'Neill FA, Peltonen L, Nestadt G, Lasseter VK, Liang KY, Papadimitriou GM, Dikeos DG, Schwab SG, Owen MJ, O'Donovan MC, Norton N, Hare E, Raventos H, Nicolini H, Albus M, Maier W, Nimgaonkar VL, Terenius L, Mallet J, Jay M, Godard S, Nertney D, Alexander M, Crowe RR, Silverman JM, Bassett AS, Roy MA, Merette C, Pato CN, Pato MT, Roos JL, Kohn Y, Amann-Zalcenstein D, Kalsi G, McQuillin A, Curtis D, Brynjolfson J, Sigmundsson T, Petursson H, Sanders AR, Duan J, Jazin E, Myles-Worsley M, Karayiorgou M, Lewis CM (2009). Meta-analysis of 32 genome-wide linkage studies of schizophrenia. Mol Psychiatry, 14, 774 - 785. doi:10.1038/mp.2008.135
    • International Schizophrenia C, Purcell SM, Wray NR, Stone JL, Visscher PM, O'Donovan MC, Sullivan PF, Sklar P (2009). Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature, 460, 748 - 752. doi:10.1038/nature08185
    • Bass NJ, Datta SR, McQuillin A, Puri V, Choudhury K, Thirumalai S, Lawrence J, Quested D, Pimm J, Curtis D, Gurling HM (2009). Evidence for the association of the DAOA (G72) gene with schizophrenia and bipolar disorder but not for the association of the DAO gene with schizophrenia. Behav Brain Funct, 5, 28 - . doi:10.1186/1744-9081-5-28
    • Perlis RH, Smoller JW, Ferreira MA, McQuillin A, Bass N, Lawrence J, Sachs GS, Nimgaonkar V, Scolnick EM, Gurling H, Sklar P, Purcell S (2009). A genomewide association study of response to lithium for prevention of recurrence in bipolar disorder. Am J Psychiatry, 166, 718 - 725. doi:10.1176/appi.ajp.2009.08111633
    • Rapp G, McQuillin A, Brett PM, Tonetti MS, Donos N (2009). Evidence of linkage on 1022-23.2 to periodontitis in Brazilian families.

    2008

    • Knapp S, Hosie AM, Anstee QM, Thomos P, Mortensen M, Martinez A, Tymowska-Lalanne Z, McQuillin A, Gurling HM, Morgan MY, Kuo YT, Herlihy A, Bell JD, Robinson I, Fisher E, Brown S, Stephens D, Smart TG, Thomas HC (2008). IDENTIFICATION OF A MODEL OF ALCOHOL PREFERENCE AND ITS SIMILARITY TO HUMAN ALCOHOLISM.
    • Sklar P, Smoller JW, Fan J, Ferreira MA, Perlis RH, Chambert K, Nimgaonkar VL, McQueen MB, Faraone SV, Kirby A, de Bakker PI, Ogdie MN, Thase ME, Sachs GS, Todd-Brown K, Gabriel SB, Sougnez C, Gates C, Blumenstiel B, Defelice M, Ardlie KG, Franklin J, Muir WJ, McGhee KA, MacIntyre DJ, McLean A, VanBeck M, McQuillin A, Bass NJ, Robinson M, Lawrence J, Anjorin A, Curtis D, Scolnick EM, Daly MJ, Blackwood DH, Gurling HM, Purcell SM (2008). Whole-genome association study of bipolar disorder. Mol Psychiatry, 13, 558 - 569. doi:10.1038/sj.mp.4002151
    • Hennah W, Thomson P, McQuillin A, Bass N, Loukola A, Anjorin A, Blackwood D, Curtis D, Deary IJ, Harris E, Isometsä ET, Lawrence , Lönnqvist J, Muir M, Palotie A, Partonen T, Paunio T, Pylkkö E, Robinson M, Soronen P, Suominen K, Suvisaari J, Thirumalai S, StClair D, Gurling H, Peltonen L, P D DA (2008). Heterogeneity and Interplay in Schizophrenia and Bipolar Disorder. Molecular Psychiatry, , - .
    • Puri V, McQuillin A, Datta S, Choudhury K, Pimm J, Thirumalai S, Krasucki R, Lawrence J, Quested D, Bass N, Crombie C, Fraser G, Walker N, Moorey H, Ray MK, Sule A, Curtis D, St Clair D, Gurling H (2008). Confirmation of the genetic association between the U2AF homology motif (UHM) kinase 1 (UHMK1) gene and schizophrenia on chromosome 1q23.3. Eur J Hum Genet, 16, 1275 - 1282. doi:10.1038/ejhg.2008.76
    • International Schizophrenia C (2008). Rare chromosomal deletions and duplications increase risk of schizophrenia. Nature, 455, 237 - 241. doi:10.1038/nature07239
    • Puri V, McQuillin A, Datta S, Choudhury K, Pimm J, Thirumalai S, Krasucki R, Lawrence J, Quested D, Bass N, Crombie C, Fraser G, Walker N, Moorey H, Ray MK, Sule A, Curtis D, St Clair D, Gurling H (2008). Confirmation of the genetic association between the U2AF homology motif (UHM) kinase 1 (UHMK1) gene and schizophrenia on chromosome 1q23.3.. Eur J Hum Genet, 16(10), 1275 - 1282. doi:10.1038/ejhg.2008.76
    • Ferreira MA, O'Donovan MC, Meng YA, Jones IR, Ruderfer DM, Jones L, Fan J, Kirov G, Perlis RH, Green EK, Smoller JW, Grozeva D, Stone J, Nikolov I, Chambert K, Hamshere ML, Nimgaonkar VL, Moskvina V, Thase ME, Caesar S, Sachs GS, Franklin J, Gordon-Smith K, Ardlie KG, Gabriel SB, Fraser C, Blumenstiel B, Defelice M, Breen G, Gill M, Morris DW, Elkin A, Muir WJ, McGhee KA, Williamson R, MacIntyre DJ, MacLean AW, St CD, Robinson M, Van Beck M, Pereira AC, Kandaswamy R, McQuillin A, Collier DA, Bass NJ, Young AH, Lawrence J, Ferrier IN, Anjorin A, Farmer A, Curtis D, Scolnick EM, McGuffin P, Daly MJ, Corvin AP, Holmans PA, Blackwood DH, Gurling HM, Owen MJ, Purcell SM, Sklar P, Craddock N, Wellcome Trust Case Control C (2008). Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nat Genet, 40, 1056 - 1058. doi:10.1038/ng.209

    2007

    • Choudhury K, McQuillin A, Puri V, Pimm J, Datta S, Thirumalai S, Krasucki R, Lawrence J, Bass NJ, Quested D, Crombie C, Fraser G, Walker N, Nadeem H, Johnson S, Curtis D, St Clair D, Gurling HM (2007). A genetic association study of chromosome 11q22-24 in two different samples implicates the FXYD6 gene, encoding phosphohippolin, in susceptibility to schizophrenia.. Am J Hum Genet, 80(4), 664 - 672. doi:10.1086/513475
    • McQuillin A, Rizig M, Gurling HM (2007). A microarray gene expression study of the molecular pharmacology of lithium carbonate on mouse brain mRNA to understand the neurobiology of mood stabilization and treatment of bipolar affective disorder. Pharmacogenet Genomics, 17, 605 - 617. doi:10.1097/FPC.0b013e328011b5b2
    • Gurling H, Pimm J, McQuillin A (2007). Replication of genetic association studies between markers at the Epsin 4 gene locus and schizophrenia in two Han Chinese samples. Schizophr Res, 89, 357 - 359. doi:10.1016/j.schres.2006.08.024
    • Datta SR, McQuillin A, Puri V, Choudhury K, Thirumalai S, Lawrence J, Pimm J, Bass N, Lamb G, Moorey H, Morgan J, Punukollu B, Kandasami G, Kirwin S, Sule A, Quested D, Curtis D, Gurling HM (2007). Failure to confirm allelic and haplotypic association between markers at the chromosome 6p22.3 dystrobrevin-binding protein 1 (DTNBP1) locus and schizophrenia. Behav Brain Funct, 3, 50 - . doi:10.1186/1744-9081-3-50
    • Guerrini I, McQuillin A, Thomson AD, Gurling HMD (2007). Genetic linkage supports the presence oftwo susceptibility loci on chromosome 1p22.1-11.2 and 1q21.3-24.2 in alcoholism.
    • Puri V, McQuillin A, Choudhury K, Datta S, Pimm J, Thirumalai S, Krasucki R, Lawrence J, Quested D, Bass N, Moorey H, Morgan J, Punukollu B, Kandasami G, Curtis D, Gurling H (2007). Fine mapping by genetic association implicates the chromosome 1q23.3 gene UHMK1, encoding a serine/threonine protein kinase, as a novel schizophrenia susceptibility gene. Biol Psychiatry, 61, 873 - 879. doi:10.1016/j.biopsych.2006.06.014
    • Choudhury K, McQuillin A, Thirumalai S, Lawrence J, Krasucki R, Puri V, Datta S, Quested D, Bass N, Pimm J, Kandasami G, Morgan J, Punukollu B, Nadeem H, Curtis D, Gurling H (2007). A genetic association study implicates the chromosome 11q23.3 gene FXYD6 encoding phopshohippolin in susceptibility to schizophrenia in University College London and Aberdeen case control samples. The American Journal of Human Genetics, 80(4), 664 - 672.
    • Gurling HMD, Critchley H, Datta SR, McQuillin A, Blaveri E, Thirumalai S, Pimm J, Krasucki R, Kalsi G, Quested D, Lawrence J, Bass N, Choudhury K, Puri V, O'Daly O, Curtis D, Blackwood D, Muir W, Malhotra AK, Buchanan RW, Good CD, Frackowiak RSJ, Dolan RJ (2007). Gene-brain structure relationships: arbitrary assumptions of heterogeneity generate unfalsifiable claims - In reply. ARCH GEN PSYCHIAT, 64(9), 1098 - 1099.

    2006

    • Bass N, McQuillin A, Lawrence J, Choudhury K, Puri V, Kalsi G, Curtis D, Gurling H (2006). Failure to confirm allelic association between COMT and bipolar disorder in a large UK sample.
    • Pereira ACP, McQuillin A, Mors O, Olsen IM, Puri V, Choudhury K, Bass NJ, Gurling HM (2006). Detection and characterisation of the bipolar susceptibility gene Slynar in the mouse.
    • Choudhury K, McQuillin A, Puri V, Thirumalai S, Lawrence J, Krasucki R, Datta SR, Bass NJ, Pimm J, Curtis D, Gurling HMD (2006). A genetic association study implicates the chromosome 11q23.3 gene FXYD6 in susceptibility to schizophrenia.
    • McQuillin A, Rizig M, Gurling H (2006). A microarray gene expression study of the effects lithium carbonate on mouse brain mRNA in order to understand the neurobiology of mood stabilisation and treatment of bipolar affective disorder.
    • Puri V, McQuillin A, Thirumalai S, Lawrence J, Krasucki R, Choudhury K, Datta S, Kerwin S, Quested D, Bass N, Pimm J, Lamb G, Moorey H, Kandasami G, Badacsonyi A, Kelly K, Morgan J, Punukollu B, Nadeem H, Curtis D, Gurling HM (2006). Failure to confirm allelic association between markers at the CAPON gene locus and schizophrenia in a British sample. Biol Psychiatry, 59, 195 - 197. doi:10.1016/j.biopsych.2005.08.015
    • Kalsi G, McQuillin A, Degn B, Lundorf MD, Bass NJ, Lawrence J, Choudhury K, Puri V, Nyegaard M, Curtis D, Mors O, Kruse T, Kerwin S, Gurling H (2006). Identification of the Slynar gene (AY070435) and related brain expressed sequences as a candidate gene for susceptibility to affective disorders through allelic and haplotypic association with bipolar disorder on chromosome 12q24. Am J Psychiatry, 163, 1767 - 1776. doi:10.1176/appi.ajp.163.10.1767
    • Gurling HM, Critchley H, Datta SR, McQuillin A, Blaveri E, Thirumalai S, Pimm J, Krasucki R, Kalsi G, Quested D, Lawrence J, Bass N, Choudhury K, Puri V, O'Daly O, Curtis D, Blackwood D, Muir W, Malhotra AK, Buchanan RW, Good CD, Frackowiak RS, Dolan RJ (2006). Genetic association and brain morphology studies and the chromosome 8p22 pericentriolar material 1 (PCM1) gene in susceptibility to schizophrenia. Arch Gen Psychiatry, 63, 844 - 854. doi:10.1001/archpsyc.63.8.844
    • McQuillin A, Bass NJ, Kalsi G, Lawrence J, Puri V, Choudhury K, Detera-Wadleigh SD, Curtis D, Gurling HM (2006). Fine mapping of a susceptibility locus for bipolar and genetically related unipolar affective disorders, to a region containing the C21ORF29 and TRPM2 genes on chromosome 21q22.3. Mol Psychiatry, 11, 134 - 142. doi:10.1038/sj.mp.4001759
    • Rizig MA, McQuillin A, Puri V, Choudhury K, Datta S, Thirumalai S, Lawrence J, Quested D, Pimm J, Bass N, Lamb G, Moorey H, Badacsonyi A, Kelly K, Morgan J, Punukollu B, Kandasami G, Curtis D, Gurling H (2006). Failure to confirm genetic association between schizophrenia and markers on chromosome 1q23.3 in the region of the gene encoding the regulator of G-protein signaling 4 protein (RGS4). Am J Med Genet B Neuropsychiatr Genet, 141B, 296 - 300. doi:10.1002/ajmg.b.30288
    • Kandaswamy R, Bass N, Choudhury K, Puri V, Mcquillin A, Lawrence J, Curtis D, Gurling H (2006). Fine mapping of a new bipolar and unipolar affective disorder locus on chromosome 1p36.

    2005

    • Choudhury KH, Rizig MA, McQuillin A, Puri V, Datta SR, Thirumalai S, Lawrence J, Bass N, Curtis D, Gurling HM (2005). Genetic association and gene expression studies implicate the chromosome 11q23.3 gene FXYD2 in susceptibility to schizophrenia.
    • Pimm J, McQuillin A, Thirumalai S, Lawrence J, Quested D, Bass N, Lamb G, Moorey H, Datta SR, Kalsi G, Badacsonyi A, Kelly K, Morgan J, Punukollu B, Curtis D, Gurling H (2005). The Epsin 4 gene on chromosome 5q, which encodes the clathrin-associated protein enthoprotin, is involved in the genetic susceptibility to schizophrenia. Am J Hum Genet, 76, 902 - 907. doi:10.1086/430095
    • Guerrini I, Cook CC, Kest W, Devitgh A, McQuillin A, Curtis D, Gurling HM (2005). Genetic linkage analysis supports the presence of two susceptibility loci for alcoholism and heavy drinking on chromosome 1p22.1-11.2 and 1q21.3-24.2. BMC Genet, 6, 11 - . doi:10.1186/1471-2156-6-11
    • Rizig M, Gurling H, McQuillin A, Stephen HP (2005). A gene expression study of clozapine compared to haloperidol and how these drugs interact with genes implicated in schizophrenia.
    • McQuillin A, Kalsi G, Degn B, Lundorf MD, Bass NJ, Lawrence J, Choudhury K, Puri VH, Nyegaard M, Curtis D, Mors O, Kruse T, Gurling HM (2005). Allelic and haplotypic association with bipolar disorder implicates a 300 kilobase region on chromosome 12q24.3 containing novel brain expressed gene sequences.
    • Bass N, McQuillin A, Lawrence J, Choudhury , Puri V, Kalsi G, Curtis D, Gurling HM (2005). Evidence of allelic association of bipolar disorder with two genes P2RX7 and AY070435 6 MB apart on 12q24.
    • Datta SR, McQuillin A, Rizig MA, Puri V, Choudhury KH, Thirumalai S, Lawrence J, Bass N, Curtis D, Gurling HM (2005). Detection of potential aetiological base pair changes causing genetic susceptibility to schizophrenia in the pericentriolar material 1 (PCM1) gene on chromosome 8p22 supports evidence from allelic association.
    • Puri V, Rizig MA, McQuillin A, Choudhury KH, Datta SR, Thirumalai S, Lawrence J, Bass N, Moorey H, Badacsonyi A, Kelly K, Morgan J, Punukollu B, Gurling H (2005). Failure to confirm association between schizophrenia and markers on chromosome 1q23.3 at the RGS4 and CAPON genes.
    • Guerrini I, Thomson AD, Cook CC, McQuillin A, Sharma V, Kopelman M, Reynolds G, Jauhar P, Harper C, Gurling HM (2005). Direct genomic PCR sequencing of the high affinity thiamine transporter (SLC19A2) gene identifies three genetic variants in Wernicke Korsakoff syndrome (WKS). Am J Med Genet B Neuropsychiatr Genet, 137B, 17 - 19. doi:10.1002/ajmg.b.30194

    2004

    • McQuillin A, Bass N, Kalsi G, Lawrence J, Smyth C, Curtis D, Gurling HMD (2004). Resequencing of the TRPM2 and TSPEAR genes provides additional SNPs in the 21q22.3 region of chromosome 21 that show strengthened allelic and haploptypic association with bipolar disorder.
    • Rizig MA, McQuillin A, Datta SR, Pimm J, Thirumalai S, Moorey H, Quested DD, Kalsi G, Bass N, Lawrence J, Curtis D, Hubank M, Hunt SP, Gurling HMD (2004). A microarray gene expression and genetic association study of the RGS4 gene in schizophrenia.
    • Buttenschon HN, Mors O, Ewald H, McQuillin A, Kalsi G, Lawrence J, Gurling H, Kruse TA (2004). No association between a neuronal nitric oxide synthase (NOS1) gene polymorphism on chromosome 12q24 and bipolar disorder. Am J Med Genet B Neuropsychiatr Genet, 124B, 73 - 75. doi:10.1002/ajmg.b.20040
    • Rizig MA, McQuillin A, Hubank M, Hunt SP, Gurling HMD (2004). A microarray gene expression study of the side effects of the antipsychotic drugs clozapine and haloperidol: Antipsychotic metabolic signatures in the right side of the mouse brain as model for the treatment of schizophrenia.
    • Puri V, Rizig MA, Datta SR, McQuillin A, Thirumalai S, Pimm J, Moorey H, Quested D, Kalsi G, Bass N, Lawrence J, Curtis D, Gurling HMD (2004). Fine mapping of the chromosome 1q23-24.2 schizophrenia susceptibility region near the RGS4 D1S196 and Capon loci.
    • Choudhury K, Puri V, McQuillin A, Kalsi G, Bass N, Lawrence J, Curtis D, Gurling HMD (2004). Attempted confirmation of the fine mapping of a putative bipolar susceptibility locus on chromosome 4P16.1 at the PPP2R2C gene locus.
    • Curtis D, Brett P, Dearlove AM, McQuillin A, Kalsi G, Robertson MM, Gurling HM (2004). Genome scan of Tourette syndrome in a single large pedigree shows some support for linkage to regions of chromosomes 5, 10 and 13. Psychiatr Genet, 14, 83 - 87.
    • Rizig M, McQuillin A, Hubank M, Hunt S, Gurling H (2004). The molecular pharmacology behind the antipsychotic and antimanic effects of clozapine: microarray gene expression profiles of the conventional antipsychotic drug haloperidol compared with the atypical antipsychotic clozapine.

    2003

    • Segurado R, Detera-Wadleigh SD, Levinson DF, Lewis CM, Gill M, Nurnberger JI, Craddock N, DePaulo JR, Baron M, Gershon ES, Ekholm J, Cichon S, Turecki G, Claes S, Kelsoe JR, Schofield PR, Badenhop RF, Morissette J, Coon H, Blackwood D, McInnes LA, Foroud T, Edenberg HJ, Reich T, Rice JP, Goate A, McInnis MG, McMahon FJ, Badner JA, Goldin LR, Bennett P, Willour VL, Zandi PP, Liu J, Gilliam C, Juo SH, Berrettini WH, Yoshikawa T, Peltonen L, Lonnqvist J, Nothen MM, Schumacher J, Windemuth C, Rietschel M, Propping P, Maier W, Alda M, Grof P, Rouleau GA, Del-Favero J, Van Broeckhoven C, Mendlewicz J, Adolfsson R, Spence MA, Luebbert H, Adams LJ, Donald JA, Mitchell PB, Barden N, Shink E, Byerley W, Muir W, Visscher PM, Macgregor S, Gurling H, Kalsi G, McQuillin A, Escamilla MA, Reus VI, Leon P, Freimer NB, Ewald H, Kruse TA, Mors O, Radhakrishna U, Blouin JL, Antonarakis SE, Akarsu N (2003). Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder. Am J Hum Genet, 73, 49 - 62. doi:10.1086/376547
    • Carbonell J, Allen R, Kalsi G, McQuillin A, Livingston G, Katona C, Walker Z, Katz A, Rands G, Stevens T, Crossan I, Curtis D, Gurling H (2003). Variation in the DCP1 gene, encoding the angiotensin converting enzyme ACE, is not associated with increased susceptibility to Alzheimer's disease. Psychiatr Genet, 13, 47 - 50. doi:10.1097/01.ypg.0000054711.85338.5c
    • Lewis CM, Levinson DF, Wise LH, DeLisi LE, Straub RE, Hovatta I, Williams NM, Schwab SG, Pulver AE, Faraone SV, Brzustowicz LM, Kaufmann CA, Garver DL, Gurling HM, Lindholm E, Coon H, Moises HW, Byerley W, Shaw SH, Mesen A, Sherrington R, O'Neill FA, Walsh D, Kendler KS, Ekelund J, Paunio T, Lonnqvist J, Peltonen L, O'Donovan MC, Owen MJ, Wildenauer DB, Maier W, Nestadt G, Blouin JL, Antonarakis SE, Mowry BJ, Silverman JM, Crowe RR, Cloninger CR, Tsuang MT, Malaspina D, Harkavy-Friedman JM, Svrakic DM, Bassett AS, Holcomb J, Kalsi G, McQuillin A, Brynjolfson J, Sigmundsson T, Petursson H, Jazin E, Zoega T, Helgason T (2003). Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia. Am J Hum Genet, 73, 34 - 48. doi:10.1086/376549
    • Curtis D, Kalsi G, Brynjolfsson J, McInnis M, O'Neill J, Smyth C, Moloney E, Murphy P, McQuillin A, Petursson H, Gurling H (2003). Genome scan of pedigrees multiply affected with bipolar disorder provides further support for the presence of a susceptibility locus on chromosome 12q23-q24, and suggests the presence of additional loci on 1p and 1q. Psychiatr Genet, 13, 77 - 84. doi:10.1097/01.ypg.0000056684.89558.d2

    2002

    • McQuillin A, Kalsi G, Lawrence J, Smyth C, Curtis D, Bass NJ, Gurling HMD (2002). Positive allelic association of the marker d21sl71 with bipolar disorder identifies TRPC7, a calcium channel protein on chromosome 21 at 21q22.3, as being a candidate gene for increasing genetic susceptibility to bipolar and related unipolar affective disorders..
    • Guerrini I, Cook CH, Kest W, Devitgh A, McQuillin A, Curtis D, Gurling HMD (2002). Genome scan of alcoholism in multiplex British families supports the presence of susceptibility loci on chromosome 1p and 1q.
    • Kalsi G, Rizig MAA, Theobald S, Mcquillin A, Bass N, Curtis D, Pickard B, Blackwood D, Gurling HMD (2002). An allelic association study in a UK case-control sample testing the schizophrenia susceptibility locus on chromosome 1q21-22.
    • Jorgensen TH, Degn B, Wang AG, Vang M, Gurling H, Kalsi G, McQuillin A, Kruse TA, Mors O, Ewald H (2002). Linkage disequilibrium and demographic history of the isolated population of the Faroe Islands. Eur J Hum Genet, 10, 381 - 387. doi:10.1038/sj.ejhg.5200816
    • McQuillin A, Kalsi G, Moorey H, Lamb G, Mayet S, Quested D, Baker P, Curtis D, Gurling HM (2002). A novel polymorphism in exon 11 of the WKL1 gene, shows no association with schizophrenia. EUR J HUM GENET, 10(8), 491 - 494. doi:10.1038/sj/ejhg.5200837
    • Kalsi G, Mcquillin A, Curtis D, Bass N (2002). Allelic association study investigating GABRA3 and markers in G6PD region in a UK bipolar case-control sample..
    • Blaveri E, Critchley HD, Gurling HMD, O'Daly O, Kalsi G, Datta SR, McQuillin A, Moorey H, Quested D, Curtis D, Lawrence J, Bass N, Good CD, Frackowiak RS, Dolan R (2002). Genetic markers showing linkage disequilibrium with a chromosome 8p22 schizophrenia susceptibility locus near the pericentriolar material gene (PCM1) are associated with reduced left orbitofrontal cortex grey matter volume and other cerebral morphology changes at MRI compared to non chromosome 8p22 associated schizophrenics..
    • Rizig MA, McQuillin A, Fletcher D, Hubank M, Hunt SP, Gurling HMD (2002). Differences in mouse brain microarray detected gene expression profiles in response to the antipsychotic drugs Clozapine and haloperidol: What gene expression pathways mediate clozapine's superior clinical efficacy?.
    • Kalsi G, Lawrence J, Mcquillin A, Curtis D, Bass N, Gurling HMD (2002). X linkage in bipolar disorder: Allelic association studies of the Xq26-28 region implicate the G6PD locus and flanking region but not the a3 subunit of the GABA receptor gene (GABRA3) in a UK bipolar case-control sample.
    • Bass N, McQuillin A, Lawrence J, Darragh N, Kalsi G, Curtis D, Gurling HMD (2002). Investigation of the gene encoding tryptophan hydroxylase (TPH) and suicide behaviour in bipolar affective disorder shows allelic association with poor pre-morbid social and work adjustment and with violent suicide.
    • Gurling HMD, Blaveri E, Datta S, Kalsi G, McQuillin A, Moorey H, Quested D, Lamb G, Lawrence J, Chowdhury U, Bass N, O'Daly O, Curtis D, Critchley HD, Good CD, Frackowiak RSJ, Dolan R (2002). Genetic markers showing linkage disequilibrium with a chromosome 8p22 schizophrenia susceptibility locus near the pericentriolar material gene (PCM1) are associated with reduced left orbitofrontal cortex grey matter volume and other cerebral morphology changes at MRI compared to non chromosome 8p22 associated schizophrenics.
    • McQuillin A, Kalsi G, Lawrence J, Smyth C, Curtis D, Bass N, Gurling HMD (2002). Positive allelic association of the marker D21S171 with bipolar disorder identifies TRPC7, a calcium channel protein on chromosome 21 at 21q22.3, as being a candidate gene for increasing susceptibility to bipolar and related unipolar affective disorders.

    2001

    • Guerrini I, Cook CCH, Kest W, Devitgh A, McQuillin A, Kalsi G, Curtis D, Gurling HMD (2001). Systematic genome scan of alcoholism using genetic linkage analysis in multiplex British families supports the presence of susceptibility loci on chromosome 1p and 16p..
    • Blaveri E, Kalsi G, Lawrence J, Quested D, Moorey H, Lamb G, Kohen D, Shiwach R, Chowdhury U, Curtis D, McQuillin A, Gramoustianou ES, Gurling HM (2001). Genetic association studies of schizophrenia using the 8p21-22 genes: prepronociceptin (PNOC), neuronal nicotinic cholinergic receptor alpha polypeptide 2 (CHRNA2) and arylamine N-acetyltransferase 1 (NAT1). Eur J Hum Genet, 9, 469 - 472. doi:10.1038/sj.ejhg.5200646
    • McQuillin A, Kalsi G, Moorey H, Lamb G, Mayet S, Quested D, Gurling H (2001). Exon 11 of the chromosome 22 gene WKL1, previously shown to exhibit a base pair mutation in rare cases of schizophrenia, was found to contain an insertion/deletion polymorphism, affecting the receptor channel amino acid sequence..
    • Gurling HM, Kalsi G, Brynjolfson J, Sigmundsson T, Sherrington R, Mankoo BS, Read T, Murphy P, Blaveri E, McQuillin A, Petursson H, Curtis D (2001). Genomewide genetic linkage analysis confirms the presence of susceptibility loci for schizophrenia, on chromosomes 1q32.2, 5q33.2, and 8p21-22 and provides support for linkage to schizophrenia, on chromosomes 11q23.3-24 and 20q12.1-11.23. Am J Hum Genet, 68, 661 - 673. doi:10.1086/318788

    2000

    • Degn B, Lundorf MD, Bruun TG, McQuillin A, Lawrence J, Curtis D, Kalsi G, Chen A, Mors O, Kruse TA, Gurling H, Ewald H (2000). A search for the risk allele for bipolar affective disorder on chromosome 12q24.2..
    • Guerrini I, Cook CC, Kest W, Devitgh A, McQuillin A, Holmes D, Turner A, Curtis D, Gurling HMD (2000). Report of a total genome scan for genes increasing susceptibility to alcoholism by genetic linkage analysis in multiplex British families..

    1999

    • McQuillin A, Lawrence J, Kalsi G, Smyth C, Curtis D, Gurling HMD (1999). An allelic association study of multiple polymorphic markers in the chromosome 21q22.3 region implicated in bipolar affective disorder..
    • Kalsi G, McQuillin A, Lawrence J, Curtis D, Gurling HMD (1999). Positive allelic association between bipolar affective disorder and G6PD polymorphisms on chromosome Xq28..
    • McQuillin A, Lawrence J, Curtis D, Kalsi G, Smyth C, Hannesdottir S, Gurling H (1999). Adjacent genetic markers on chromosome 11p15.5 at or near the tyrosine hydroxylase locus that show population linkage disequilibrium with each other do not show allelic association with bipolar affective disorder. Psychol Med, 29, 1449 - 1454.
    • Curtis D, Kalsi G, McQuillin A, Lawrence J, Murphy P, Brynjolfsson T, McInnis M, Sigmundsson T, Petursson H, Gurling HMD (1999). Genome wide parametric genetic linkage analysis of bipolar and related unipolar affective disorders (manic depression) implicates chromosomes 1 and 12..
    • Blaveri K, Kalsi G, McQuillin A, Quested D, Read T, Murphy P, Brynjolfsson J, Sigmundsson T, Petursson H, Curtis D, Gurling HMD (1999). Linkage and allelic association studies of the 8p schizophrenia locus..
    • Degn B, Bruun TG, McQuillin A, Lawrence J, Curtis D, Kalsi G, Chen A, Kruse TA, Mors O, Gurling H, Ewald H (1999). Association study between patients with bipolar disorder and markers from the candidate region on chromosome 12q24.2-12q24.3..
    • Detera-Wadleigh SD, Barden N, Craddock N, Ewald H, Foroud T, Kelsoe J, McQuillin A (1999). Chromosomes 12 and 16 Workshop.
    • Murray KD, McQuillin A, Stewart L, Etheridge CJ, Cooper RG, Miller AD, Gurling HM (1999). Cationic liposome-mediated DNA transfection in organotypic explant cultures of the ventral mesencephalon. Gene Ther, 6, 190 - 197. doi:10.1038/sj.gt.3300743
    • McQuillin A, Lawrence J, Kalsi G, Chen A, Gurling H, Curtis D (1999). No allelic association between bipolar affective disorder and the tryptophan hydroxylase gene. Arch Gen Psychiatry, 56, 99 - 101.
    • Gurling HMD, Kalsi G, Blaveri E, McQuillin A, Read T, Murphy P, Butler R, Brynjolfsson J, Sigmundsson T, Petursson H, Curtis D (1999). Initial genome wide parametric genetic linkage analysis of schizophrenia and schizophrenia spectrum disorders finds lod scores above 3.00 on four chromosomes at 1Q22-23, 5Q22-35, 8P21-23 and 11Q14-24. a further lod above 3.00 at 4Q21-31 was found within a single family..

    1998

    • McQuillin A, Lawrence J, Curtis D, Kalsi G, Smyth C, Gurling HMD (1998). No allelic association between bipolar affective disorder and the tryptophan hydroxylase gene (TPH)..
    • McQuillin A, Lawrence J, Curtis D, Kalsi G, Smyth C, Gurling HMD (1998). No linkage found between chromosome 11p15.5 markers and manic-depressive illness..
    • McQuillin A, Lawrence J, Curtis D, Kalsi G, Smyth C, Gurling HMD (1998). An allelic association study of candidate genes in the chromosome 21q22.3 region implicated in bipolar affective disorder.

    1997

    • McQuillin A, Murray K, Stuart L, Etheridge CJ, Cooper RG, Miller AD, Gurling HMD (1997). Intrathecal administration of cationic liposome vectors for gene delivery to the central nervous system..
    • McQuillin A, Murray KD, Etheridge CJ, Stewart L, Cooper RG, Brett PM, Miller AD, Gurling HM (1997). Optimization of liposome mediated transfection of a neuronal cell line.. Neuroreport, 8(6), 1481 - 1484.
    • Murray KD, McQuillin A, Gurling HMD (1997). Cationic liposome-mediated transfection of postmitotic ND7 and dorsal root ganglion neurons.. AM J MED GENET, 74(6), 603 - 603.