Prof Sandy Macrobert

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Personal Profile

Name: Sandy Macrobert Email: a.macrobert@ucl.ac.uk
Title: Prof Tel:
Department: Research Department of General Surgery Fax:
Position: Professor of Photochemistry and Photobiology Address: Charles Bell House, 67-73 Riding House St, London, W1W7EJ
Research Domain: Biomedical Imaging (Frontier Disciplines), Cancer, Nanotechnology (Frontier Disciplines), Personalised Medicine Web Page: Personal Web Page

Profile

Research Description


Research Activities

Optical Therapy and Diagnostics

Photodynamic Therapy

Education Description

UCL Collaborators

Dr Laurence Lovat; Dr Sandy Mosse; Dr Elnaz Yaghini; Miss Melissa Bovis; Prof Stephen Bown; Dr Josephine Helen Woodhams; Dr Adil Butt

External Collaborators

Publications

    2013

    • Kimani SG, Phillips JB, Bruce JI, Golding JP, Shmigol TA, Malakhov MV, Hammond S, MacRobert AJ (2013). Fully protected glycosylated zinc (II) phthalocyanine shows high uptake and photodynamic cytotoxicity in MCF-7 cancer cells. Photochemistry and Photobiology, 89(1), 139 - 149. doi:10.1111/j.1751-1097.2012.01204.x
    • Wong JP, MacRobert AJ, Cheema U, Brown RA (2013). Mechanical anisotropy in compressed collagen produced by localised photodynamic cross-linking.. J Mech Behav Biomed Mater, 18, 132 - 139. doi:10.1016/j.jmbbm.2012.11.002
    • Noimark S, Parkin IP, Bovis M, MacRobert AJ, Correia A, Allan E, Wilson M (2013). Photobactericidal polymers; The incorporation of crystal violet and nanogold into medical grade silicone. RSC Advances, 3(40), 18383 - 18394. doi:10.1039/c3ra42629g
    • Kimani SG, Shmigol TA, Hammond S, Phillips JB, Bruce JI, MacRobert AJ, Malakhov MV, Golding JP (2013). Fully protected glycosylated zinc (II) phthalocyanine shows high uptake and photodynamic cytotoxicity in MCF-7 cancer cells.. Photochem Photobiol, 89(1), 139 - 149. doi:10.1111/j.1751-1097.2012.01204.x
    • Abbasakoor F, Farooqui N, Boulos P, Woodhams J, Bown S, MacRobert A, Novelli M (2013). Safe ablation of the anal mucosa and perianal skin in rats using Photodynamic Therapy-A promising approach for treating Anal Intraepithelial Neoplasia. Photodiagnosis and Photodynamic Therapy, , - . doi:10.1016/j.pdpdt.2013.06.003
    • Nazir S, Hussain T, Ayub A, Rashid U, Macrobert AJ (2013). Nanomaterials in combating cancer: Therapeutic applications and developments.. Nanomedicine, , - . doi:10.1016/j.nano.2013.07.001
    • Wang JT, Berg K, Høgset A, Bown SG, MacRobert AJ (2013). Photophysical and photobiological properties of a sulfonated chlorin photosensitiser TPCS(2a) for photochemical internalisation (PCI).. Photochem Photobiol Sci, 12(3), 519 - 526. doi:10.1039/c2pp25328c
    • Bovis MJ, Woodhams JH, Rojnik M, Kocbek P, Kos J, Bown SG, MacRobert AJ, Loizidou M (2013). M-THPC delivery via pegylated plga nanoparticles for in vivo photodynamic therapy (PDT).
    • Yaghini E, Giuntini F, Eggleston IM, Suhling K, Seifalian AM, Macrobert AJ (2013). Fluorescence Lifetime Imaging and FRET-Induced Intracellular Redistribution of Tat-Conjugated Quantum Dot Nanoparticles through Interaction with a Phthalocyanine Photosensitiser.. Small, , - . doi:10.1002/smll.201301459

    2012

    • Wong JPF, MacRobert AJ, Cheema U, Brown RA (2012). Engineering anisotropy in mechanical properties by orientated collagen cross-linking. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE, 6, 162 - 163.
    • François A, Bezdetnaya L, Guillemin F, D'Hallewin M-A, Battah S, MacRobert AJ (2012). Fluorescence diagnosis of bladder cancer: A novel in vivo approach using 5-aminolevulinic acid (ALA) dendrimers. BJU International, 110(11 C), - . doi:10.1111/j.1464-410X.2012.11407.x
    • Wright KE, Phillips JB, MacRobert AJ (2012). Inhibition of specific cellular antioxidant pathways increases the sensitivity of neurons to meta-tetrahydroxyphenyl chlorin-mediated photodynamic therapy in a 3d co-culture model. Photochemistry and Photobiology, 88(6), 1539 - 1545. doi:10.1111/j.1751-1097.2012.01185.x
    • Cheema U, Rong Z, Kirresh O, Macrobert AJ, Vadgama P, Brown RA (2012). Oxygen diffusion through collagen scaffolds at defined densities: implications for cell survival in tissue models.. J Tissue Eng Regen Med, 6(1), 77 - 84. doi:10.1002/term.402
    • Kimani SG, Phillips JB, Bruce JI, Golding JP, MacRobert AJ (2012). Antioxidant inhibitors potentiate the cytotoxicity of photodynamic therapy. Photochemistry and Photobiology, 88(1), 175 - 187. doi:10.1111/j.1751-1097.2011.01022.x
    • Adigbli DK, Seebaluk J, Macrobert AJ, Loizidou M (2012). Bioluminescence mediated photodynamic therapy in breast cancer cell line.
    • Adigbli DK, MacRobert AJ (2012). Photochemical internalisation: the journey from basic scientific concept to the threshold of clinical application.. Curr Opin Pharmacol, 12(4), 434 - 438. doi:10.1016/j.coph.2012.04.005
    • Wright KE, MacRobert AJ, Phillips JB (2012). Inhibition of specific cellular antioxidant pathways increases the sensitivity of neurons to meta-tetrahydroxyphenyl chlorin-mediated photodynamic therapy in a 3D co-culture model.. Photochem Photobiol, 88(6), 1539 - 1545. doi:10.1111/j.1751-1097.2012.01185.x
    • François A, Battah S, MacRobert AJ, Bezdetnaya L, Guillemin F, D'Hallewin MA (2012). Fluorescence diagnosis of bladder cancer: a novel in vivo approach using 5-aminolevulinic acid (ALA) dendrimers.. BJU Int, 110(11 Pt C), E1155 - E1162. doi:10.1111/j.1464-410X.2012.11407.x
    • Rojnik M, Kocbek P, Moret F, Compagnin C, Celotti L, Bovis MJ, Woodhams JH, Macrobert AJ, Scheglmann D, Helfrich W, Verkaik MJ, Papini E, Reddi E, Kos J (2012). In vitro and in vivo characterization of temoporfin-loaded PEGylated PLGA nanoparticles for use in photodynamic therapy.. Nanomedicine (Lond), 7(5), 663 - 677. doi:10.2217/nnm.11.130

    2011

    • Cheema U, Alekseeva T, Kirresh O, Brown RA, MacRobert AJ, Rong Z, Vadgama P (2011). O diffusion through collagen scaffolds at defined densities: Implications for cell survival and angiogenic signalling in tissue models. IFMBE Proceedings, 30 IFMBE, 13 - 16. doi:10.1007/978-3-642-19044-5_4
    • Jawad H, Kuraishi A, Alkseeva T, Brown R, Austwick M, MacRobert S, Tully F (2011). Monitoring collagen gelling by elastic scattering spectroscopy (ESS).
    • Compagnin C, Moret F, Celotti L, Miotto G, Woodhams JH, MacRobert AJ, Scheglmann D, Iratni S, Reddi E (2011). Meta-tetra(hydroxyphenyl)chlorin-loaded liposomes sterically stabilised with poly(ethylene glycol) of different length and density: characterisation, in vitro cellular uptake and phototoxicity.. Photochem Photobiol Sci, 10(11), 1751 - 1759. doi:10.1039/c1pp05163f
    • AUSTWICK M, Woodhams JH, Chalau V, Mosse CA, Eliot C, Lovat LB, MacRobert AJ, Bigio IJ, Bown SG (2011). Optical Pharmacokinetics measurements of photosensitizer concentrations in vivo. Journal of Innovative Optical Health Sciences, 4(2), 97 - 111. doi:10.1142/S1793545811001460

    2010

    • Bourré L, Giuntini F, Eggleston IM, Mosse CA, Macrobert AJ, Wilson M (2010). Effective photoinactivation of Gram-positive and Gram-negative bacterial strains using an HIV-1 Tat peptide-porphyrin conjugate.. Photochem Photobiol Sci, 9(12), 1613 - 1620. doi:10.1039/c0pp00146e
    • Woodhams J, Lou PJ, Selbo PK, Mosse A, Oukrif D, MacRobert A, Novelli M, Peng Q, Berg K, Bown SG (2010). Intracellular re-localisation by photochemical internalisation enhances the cytotoxic effect of gelonin--quantitative studies in normal rat liver.. J Control Release, 142(3), 347 - 353. doi:10.1016/j.jconrel.2009.11.017

    2009

    • Yaghini E, Seifalian AM, MacRobert AJ (2009). Quantum dots and their potential biomedical applications in photosensitization for photodynamic therapy.. Nanomedicine (Lond), 4(3), 353 - 363. doi:10.2217/nnm.09.9
    • Bourre L, Giuntini F, Eggleston IM, Wilson M, MacRobert AJ (2009). Protoporphyrin IX enhancement by 5-aminolaevulinic acid peptide derivatives and the effect of RNA silencing on intracellular metabolism.. British Journal of Cancer, in press, - .
    • Giuntini F, Bourré L, Macrobert AJ, Wilson M, Eggleston IM (2009). Improved peptide prodrugs of 5-ALA for PDT: rationalization of cellular accumulation and protoporphyrin IX production by direct determination of cellular prodrug uptake and prodrug metabolization. Journal of Medicinal Chemistry, 52(13), 4026 - 4037.
    • Wright KE, Liniker E, Loizidou M, Moore C, MacRobert AJ, Phillips JB (2009). Peripheral neural cell sensitivity to mTHPC-mediated photodynamic therapy in a 3D in vitro model. British Journal of Cancer, 101(4), 658 - 665.
    • Di Venosa G, Hermida L, Fukuda H, Defain MV, Rodriguez L, Mamone L, MacRobert A, Casas A, Batlle A (2009). Comparation of liposomal formulations of ALA Undecanoyl ester for its use in photodynamic therapy.. J Photochem Photobiol B, 96(2), 152 - 158. doi:10.1016/j.jphotobiol.2009.06.001
    • Casas A, Battah S, Di Venosa GD, P F, H B, A M, A J (2009). Sustained and efficient pophyrin generation in vivo using dendrimer conjugates of 5-ALA for photodynamic therapy. Journal of Controlled Release, in press, - .

    2008

    • Wright KE, MacRobert AJ, Phillips JB (2008). Assessing the effect of photodynamic therapy on peripheral nerve and cancer cells using a thin tissue engineered collagen culture model.
    • Giuntini F, Bourre L, Wilson M, MacRobert AJ, Eggleston IM (2008). A novel approach to improve cellular delivery of 5-aminolaevulinic acid: New ALA-containing peptide Prodrugs for photodynamic therapy. J PEPT SCI, 14(8), 156 - 156.
    • Giuntini F, Bourre L, MacRobert AJ, Wilson M, Eggleston IM (2008). Quantitative determination of 5-aminolaevulinic acid and its esters in cell lysates by HPLC-fluorescence.. Journal of Chromatography B, 875, 562 - 566.
    • Austwick M, Woodhams J, Mosse CA, Elliot-Laize C, Chalau V, MacRobert AJ, Bigio IJ, Bown S (2008). Optical pharmacokinetics measurement of photosensitising drug concentrations for photodynamic therapy. Biomedical Optics, BIOMED 2008, , - .
    • Cheema U, Brown RA, Alp B, MacRobert AJ (2008). Spatially defined oxygen gradients and vascular endothelial growth factor expression in an engineered 3D cell model. Cellular and Molecular Life Sciences, 65(1), 177 - 186.
    • U Cheema TA, A J MacRobert BA, V Mudera RAB (2008). Effect of Hypoxia on Vascular Endothelial Growth Factor Expression in an Engineered 3D Cell Model.
    • R A Brown UC, B Alp ZR, V Mudera AJM (2008). Perfusion and Tissue Engineering Scaffolds: Micro versus Nano Pores.
    • Bourré L, Giuntini F, Eggleston IM, Wilson M, Macrobert AJ (2008). 5-aminolaevulinic acid peptide prodrugs enhance photosensitization for photodynamic therapy. Molecular Cancer Therapeutics, 7(6), 1720 - 1729.
    • Di Venosa G, Hermida L, Batlle A, Fukuda H, Defain MV, Mamone L, Rodriguez L, MacRobert A, Casas A (2008). Characterisation of liposomes containing aminolevulinic acid and derived esters. Journal of Photochemistry and Photobiology B: Biology, 92(1), 1 - 9.

    2007

    • Battah S, Balaratnam S, Casas A, O'Neill S, Edwards C, Batlle A, Dobbin P, MacRobert AJ (2007). Macromolecular delivery of 5-aminolaevulinic acid for photodynamic therapy using dendrimer conjugates. Molecular Cancer Therapeutics, 6(3), 876 - 885.
    • Alp B, Rong Z, Cheema U, MacRobert AJ, Vadgama P, Brown RA (2007). Measurement of glucose and oxygen concentration in biomimetic constructs.
    • Dixon MJ, Bourre L, MacRobert AJ, Eggleston IM (2007). Novel prodrug approach to photodynamic therapy: Fmoc solid-phase synthesis of a cell permeable peptide incorporating 5-aminolaevulinic acid. Bioorganic and Medicinal Chemistry Letters, 17(16), 4518 - 4522.
    • Woodhams JH, MacRobert AJ, Bown SG (2007). The role of oxygen monitoring during photodynamic therapy and its potential for treatment dosimetry. Photochemical and Photobiological Sciences, 6(12), 1246 - 1256.
    • Adigbli DK, Wilson DGG, Farooqui N, Risley P, Taylor I, MacRobert AJ, Loizidou M (2007). Photochemical internalisation of chemotherapy potentiates killing of multidrug resistant breast and bladder cancer cells.. British Journal of Cancer, 97(4), 507 - 512. doi:10.1038/sj.bjc.6603895
    • Kunz L, Connelly JP, Woodhams JH, MacRobert AJ (2007). Photodynamic modi. cation of disulfonated aluminium phthalocyanine. fluorescence in a macrophage cell line. Photochemical and Photobiological Sciences, 6(9), 940 - 948.
    • Ayaru L, Wittmann J, MacRobert AJ, Novelli M, Bown SG, Pereira SP (2007). Photodynamic therapy using verteporfin photosensitization in the pancreas and surrounding tissues in the Syrian golden hamster. Pancreatology, 7(1), 20 - 27.
    • Rodriguez L, DiVenosa G, Batlle A, MacRobert A, Casas A (2007). Response to ALA-based PDT in an immortalised normal breast cell line and its counterpart transformed with the Ras oncogene. Photochemical and Photobiological Sciences, 6(12), 1306 - 1310.

    2006

    • Wright KE, Liniker E, MacRobert AJ, Brown RA, Saffrey MJ, Phillips JB (2006). Investigating the effect of photodynamic therapy on nerves using tissue engineered culture models.
    • MacRobert AJ (2006). Photosensitising properties of protoporphyrin IX and photoprotoporphyrin in relation to photodynamic therapy. In Phillips D, Barber J (Ed.), The life and scientific legacy of George Porter (pp. 469 - 485). : Imperial College Press.
    • Di Venosa GM, Casas AG, Battah S, Dobbin P, Fukuda H, MacRobert AJ, Batlle A (2006). Investigation of a novel dendritic derivative of 5-aminolaevulinic acid for photodynamic therapy. The International Journal of Biochemistry and Cell Biology, 38(1), 82 - 91.
    • Cheema U, Alp B, Brown RA, MacRobert AJ (2006). Perfusion of oxygen in 3D plastic compressed collagen constructs.
    • Komerik N, MacRobert AJ (2006). Photodynamic therapy as an alternative antimicrobial modality for oral infections.. Journal of Environmental Pathology Toxicology and Oncology, 25(1-2), 487 - 504.
    • Rodriguez L, Batlle A, Di Venosa G, MacRobert AJ, Battah S, Daniel H, Casas A (2006). Study of the mechanisms of uptake of 5-aminolevulinic acid derivatives by PEPT1 and PEPT2 transporters as a tool to improve photodynamic therapy of tumours. The International Journal of Biochemistry and Cell Biology, 38(9), 1530 - 1539.
    • Sharwani A, Jerjes W, Hopper C, Lewis MP, El-Maaytah M, Khalil HSM, MacRobert AJ, Upile T, Salih V (2006). Photodynamic therapy down-regulates the invasion promoting factors in human oral cancer. Archives of Oral Biology, 51(12), 1104 - 1111. doi:10.1016/j.archoralbio.2006.05.012
    • Lou PJ, Lai PS, Shieh MJ, MacRobert AJ, Berg K, Bown SG (2006). Reversal of doxorubicin resistance in breast cancer cells by photochemical internalization. International Journal of Cancer, 119(11), 2692 - 2698.
    • Di Venosa G, Batlle A, Fukuda H, MacRobert A, Casas A (2006). Distribution of 5-aminolevulinic acid derivatives and induced porphyrin kinetics in mice tissues. Cancer Chemotherapy and Pharmacology, 58(4), 478 - 486.
    • Di Venosa G, Fukuda H, Batlle A, MacRobert A, Casas A (2006). Photodynamic therapy: Regulation of porphyrin synthesis and hydrolysis from ALA esters. Journal of Photochemistry and Photobiology B: Biology, 83(2), 129 - 136.
    • Sharwani A, Jerjes W, Salih V, MacRobert AJ, El-Maaytah A, Khalil HSM, Hopper C (2006). Fluorescence spectroscopy combined with 5-aminolevulinic acid-induced protoporphyrin IX fluorescence in detecting oral premalignancy. Journal of Photochemistry and Photobiology B: Biology, 83(1), 27 - 33. doi:10.1016/j.jphotobiol.2005.11.007
    • Curnow A, MacRobert AJ, Bown SG (2006). Comparing and combining light dose fractionation and iron chelation to enhance experimental photodynamic therapy with aminolevulinic acid. Lasers in Surgery and Medicine, 38(4), 325 - 331.
    • Rodriguez L, Batlle A, Di Venosa G, Battah S, Dobbin P, MacRobert AJ, Casas A (2006). Mechanisms of 5-aminolevulic acid ester uptake in mammalian cells. British Journal of Pharmacology, 147(7), 825 - 833.
    • Woodhams JH, MacRobert AJ, Novelli M, Bown SG (2006). Photodynamic therapy with WST09 (Tookad): Quantitative studies in normal colon and transplanted tumours. International Journal of Cancer, 118(2), 477 - 482. doi:10.1002/ijc.21335
    • Battah S, O'Neill S, Edwards C, Balaratnam S, Dobbin P, MacRobert AJ (2006). Enhanced porphyrin accumulation using dendritic derivatives of 5-aminolaevulinic acid for photodynamic therapy: An in vitro study. The International Journal of Biochemistry and Cell Biology, 38(8), 1382 - 1392. doi:10.1016/j.biocel.2006.02.001

    2005

    • Rogers LMA, McGivern PG, Butler AR, MacRobert AJ, Eggleston IM (2005). An efficient synthesis of 5-aminolaevulinic acid (ALA)-containing peptides for use in photodynamic therapy. Tetrahedron, 61(29), 6951 - 6958.
    • Harada M, Woodhams J, MacRobert AJ, Feneley MR, Kato H, Bown SG (2005). The vascular response to photodynamic therapy with ATX-S10Na(II) in the normal rat colon. J PHOTOCH PHOTOBIO B, 79(3), 223 - 230. doi:10.1016/j.j.photobiol.2004.08.011

    2004

    • MacRobert AJ, Theodossiou T (2004). Photodynamic therapy of cancer. In Guenther BD, Steel DG, Bayvel L (Ed.), Encyclopedia of Modern Optics (pp. 53 - 62). : Elsevier.
    • Perotti C, Fukuda H, DiVenosa G, MacRobert AJ, Batlle A, Casas A (2004). Porphyrin synthesis from ALA derivatives for photodynamic therapy. In vitro and in vivo studies. British Journal of Cancer, 90(8), 1660 - 1665.
    • Woodhams JH, Kunz L, Bown SG, MacRobert AJ (2004). Correlation of real-time haemoglobin oxygen saturation monitoring during photodynamic therapy with microvascular effects and tissue necrosis in normal rat liver. British Journal of Cancer, 91(4), 788 - 794. doi:10.1038/sj.bjc.6602036
    • Theodossiou T, Spiro MD, Jacobson J, Hothersall JS, MacRobert AJ (2004). Evidence for intracellular aggregation of hypericin and the impact on its photocytotoxicity in PAM 212 murine keratinocytes. Photochemistry and Photobiology, 80(3), 438 - 443.

    2003

    • Theodossiou T, Hothersall JS, Woods EA, Okkenhaug K, Jacobson J, MacRobert AJ (2003). Firefly luciferin-activated Rose Bengal: In vitro photodynamic therapy by intracellular chemiluminescence in transgenic NIH 3T3 cells. Cancer Research, 63(8), 1818 - 1821.
    • Komerik N, Nakanishi H, MacRobert AJ, Henderson B, Speight P, Wilson M (2003). In vivo killing of Porphyromonas gingivalis by toluidine blue-mediated photosensitization in an animal model. Antimicrobial Agents and Chemotherapy, 47(3), 932 - 940. doi:10.1128/AAC.47.3.932-940.2003
    • Woodhams JH, Kunz L, Bown SG, MacRobert AJ (2003). Monitoring the effect of PDT on in vivo oxygen saturation and microvascular circulation. Oxygen Transport to Tissue Xxv, 540, 235 - 244.

    2002

    • Marenzana M, Pickard D, MacRobert AJ, Brown RA (2002). Optical measurement of three-dimensional collagen gel constructs by elastic scattering spectroscopy. Tissue Engineering, 8(3), 409 - 418.
    • Kunz L, MacRobert AJ (2002). Intracellular photobleaching of 5,10,15,20-tetrakis(m-hydroxyphenyl) chlorin (Foscan((R))) exhibits a complex dependence on oxygen level and fluence rate. Photochemistry and Photobiology, 75(1), 28 - 35.
    • Tsutsui H, MacRobert AJ, Curnow A, Rogowska A, Buonaccorsi G, Kato H, Bown SG (2002). Optimisation of illumination for photodynamic therapy with mTHPC on normal colon and a transplantable tumour in rats. Lasers in Medical Science, 17(2), 101 - 109.
    • Komerik N, Curnow A, MacRobert AJ, Hopper C, Speight PM, Wilson M (2002). Fluorescence biodistribution and photosensitising activity of toluidine blue O on rat buccal mucosa. Lasers in Medical Science, 17(2), 86 - 92.
    • Bhatti M, MacRobert A, Henderson B, Wilson M (2002). Exposure of Porphyromonas gingivalis to red light in the presence of the light-activated antimicrobial agent toluidine blue decreases membrane fluidity. Current Microbiology, 45(2), 118 - 122.
    • Theodossiou T, MacRobert AJ (2002). Comparison of the photodynamic effect of exogenous photoprotoporphyrin and protoporphyrin IX on PAM 212 murine keratinocytes. Photochemistry and Photobiology, 76(5), 530 - 537.

    2001

    • jamieson NF, Lovat LB, MacRobert AJ, Bown SG (2001). Selectivity of mucosal ablation using photodynamic therapy with mTHPC: effect of drug-light interval, power and dose.
    • Gerscher S, Rhodes LE, Watt LP, Connelly JP, Macrobert AJ, Beijersbergen Van Henegouwen GMJ (2001). Carbon dioxide laser for removal of multiple cutaneous neurofibromas [8]. British Journal of Dermatology, 144(5), 1096 - 1098. doi:10.1046/j.1365-2133.2001.04214.x
    • Suhr MAA, Hopper C, Macrobert AJ, Speight PM, Kubler AC, Kunz L (2001). A clinical pilot study on the use of interstitial photodynamic therapy for advanced head and neck tumours. Mund-, Kiefer- und Gesichtschirurgie, 5(5), 277 - 282.
    • Oldham TC, Phillips D, MacRobert AJ (2001). Attempts to measure sensitiser photophysics in opaque tissue. Journal of Photochemistry and Photobiology B: Biology, 61(3), 129 - 136.
    • Connelly JP, Botchway SW, Kunz L, Pattison D, Parker AW, MacRobert AJ (2001). Time-resolved fluorescence imaging of photosensitiser distributions in mammalian cells using a picosecond laser line-scanning microscope. Journal of Photochemistry and Photobiology A: Chemistry, 142(2-3), 169 - 175.
    • Battah SH, Chee CE, Nakanishi H, Gerscher S, MacRobert AJ, Edwards C (2001). Synthesis and biological studies of 5-aminolevulinic acid-containing dendrimers for photodynamic therapy. Bioconjugate Chemistry, 12(6), 980 - 988.
    • Suhr MA, Hopper C, MacRobert AJ, Speight PM, Kübler AC, Kunz L (2001). [Clinical pilot study of interstitial photodynamic therapy for treatment of advanced head and neck tumors].. Mund Kiefer Gesichtschir, 5(5), 277 - 282.
    • Gerscher S, Connelly JP, van Henegouwen GMJB, MacRobert AJ, Watt P, Rhodes LE (2001). A quantitative assessment of protoporphyrin IX metabolism and phototoxicity in human skin following dose-controlled delivery of the prodrugs 5-aminolaevulinic acid and 5-aminolaevulinic acid-n-pentylester. British Journal of Dermatology, 144(5), 983 - 990.
    • Bhatti M, Nair SP, MacRobert AJ, Henderson B, Shepherd P, Cridland J, Wilson M (2001). Identification of photolabile outer membrane proteins of Porphyromonas gingivalis. Current Microbiology, 43(2), 96 - 99.

    2000

    • Suhr MAA, Hopper C, Jones L, George JGD, Bown SG, MacRobert AJ (2000). Optical biopsy systems for the diagnosis and monitoring of superficial cancer and precancer. International Journal of Oral and Maxillofacial Surgery, 29(6), 453 - 457.
    • Marenzana M, Mudera V, Sethi KK, MacRobert AJ, Brown R (2000). Novel use of photodynamic therapy for regulation of fibroblast contraction of 3D collagen constructs.
    • Bhatti M, MacRobert A, Henderson B, Shepherd P, Cridland J, Wilson M (2000). Antibody-targeted lethal photosensitization of Porphyromonas gingivalis. Antimicrobial Agents and Chemotherapy, 44(10), 2615 - 2618.
    • Gerscher S, Connelly JP, Griffiths J, Brown SB, MacRobert AJ, Wong G, Rhodes LE (2000). Comparison of the pharmacokinetics and phototoxicity of protoporphyrin IX metabolized from 5-aminolevulinic acid and two derivatives in human skin in vivo. Photochemistry and Photobiology, 72(4), 569 - 574.
    • Scott MA, Hopper C, Sahota A, Springett R, McIlroy BW, Bown SG, MacRobert AJ (2000). Fluorescence photodiagnostics and photobleaching studies of cancerous lesions using ratio imaging and spectroscopic techniques. Lasers in Medical Science, 15(1), 63 - 72.
    • Gerscher S, Wong G, Rhodes LE, Connelly JP, MacRobert AJ, Griffiths J, Brown SB (2000). Comparison of the pharmacokinetics and phototoxicity of protoporphyrin IX metabolized from 5-aminolevulinic acid and two derivatives in human skin in vivo. Photochemistry and Photobiology, 72(4), 569 - 574. doi:10.1562/0031-8655(2000)072<0569:COTPAP>2.0.CO;2

    1999

    • Casas A, Batlle AMD, Butler AR, Robertson D, Brown EH, MacRobert A, Riley PA (1999). Comparative effect of ALA derivatives on protoporphyrin IX production in human and rat skin organ cultures. British Journal of Cancer, 80(10), 1525 - 1532.
    • (1999). Topical versus systemic 5-aminolevulinic acid administration for photodynamic therapy of the colon in B10.RBP mice. Journal of Biomedical Optics, 4(3), 286 - 291.
    • Jackson Z, Meghji S, MacRobert A, Henderson B, Wilson M (1999). Killing of the yeast and hyphal forms of Candida albicans using a light-activated antimicrobial agent. Lasers in Medical Science, 14(2), 150 - 157.
    • Curnow A, McIlroy BW, Postle-Hacon MJ, MacRobert AJ, Bown SG (1999). Light dose fractionation to enhance photodynamic therapy using 5-aminolevulinic acid in the normal rat colon. Photochemistry and Photobiology, 69(1), 71 - 76.
    • Ripley PM, MacRobert AJ, Mills TN, Bown SG (1999). A comparative optical analysis of cylindrical diffuser fibres for laser therapy using fluorescence imaging. Lasers in Medical Science, 14(4), 257 - 268.
    • Fielding DI, Buonaccorsi GA, MacRobert AJ, Hanby AM, Hetzel MR, Bown SG (1999). Fine-needle interstitial photodynamic therapy of the lung parenchyma - Photosensitizer distribution and morphologic effects of treatment. Chest, 115(2), 502 - 510.

    1998

    • Bhatti M, MacRobert A, Meghji S, Henderson B, Wilson M (1998). A study of the uptake of toluidine blue O by Porphyromonas gingivalis and the mechanism of lethal photosensitization. Photochemistry and Photobiology, 68(3), 370 - 376.
    • Jenkins MP, Buonaccorsi G, MacRobert A, Bishop CCR, Bown SG, McEwan JR (1998). Intra-arterial photodynamic therapy using 5-ALA in a swine model. European Journal of Vascular and Endovascular Surgery, 16(4), 284 - 291.
    • Mlkvy P, Messmann H, Regula J, Conio M, Pauer M, Millson CE, MacRobert AJ, Bown SG (1998). Photodynamic therapy for gastrointestinal tumors using three photosensitizers - ALA induced PPIX, Photofrin (R) and MTHPC. A pilot study. Neoplasma, 45(3), 157 - 161.
    • Jenkins MP, Buonaccorsi G, MacRobert A, Bishop CCR, Bown SG, McEwan JR (1998). Pharmacokinetics and efficacy of 5-aminolaevulinic acid for endovascular photodynamic therapy in a swine model..
    • Curnow A, Postle-Hacon MJ, MacRobert AJ, Brown SG (1998). Enhancement of 5-aminolaevulinic acid induced photodynamic therapy using light dose fractionation and iron chelating agents..
    • Ketabchi A, MacRobert A, Speight PM, Bennett JH (1998). Induction of apoptotic cell death by photodynamic therapy in human keratinocytes. Archives of Oral Biology, 43(2), 143 - 149.
    • McIlroy BW, Curnow A, Buonaccorsi G, Scott MA, Bown SG, MacRobert AJ (1998). Spatial measurement of oxygen levels during photodynamic therapy using time-resolved optical spectroscopy. Journal of Photochemistry and Photobiology B: Biology, 43(1), 47 - 55.
    • Scully AD, Ostler RB, MacRobert AJ, Parker AW, de Lara C, O'Neill P, Phillips D (1998). Laser line-scanning confocal fluorescence imaging of the photodynamic action of aluminum and zinc phthalocyanines in V79-4 Chinese hamster fibroblasts. Photochemistry and Photobiology, 68(2), 199 - 204.
    • Datta SN, Loh CS, MacRobert AJ, Whatley SD, Matthews PN (1998). Quantitative studies of the kinetics of 5-aminolaevulinic acid induced fluorescence in bladder transitional cell carcinoma. British Journal of Cancer, 78(8), 1113 - 1118.
    • Curnow A, McIlroy BW, Postle-Hacon MJ, Porter JB, MacRobert AJ, Bown SG (1998). Enhancement of 5-aminolaevulinic acid-induced photodynamic therapy in normal rat colon using hydroxypyridinone iron-chelating agents. British Journal of Cancer, 78(10), 1278 - 1282.
    • Milgrom L, MacRobert S (1998). Light years ahead.. Chemistry in Britain, 34(5), 45 - 504.

    1997

    • Mlkvy P, Messman H, MacRobert AJ, Pauer M, Sams VR, Davies CL, Stewart JCM, Bown SG (1997). Photodynamic therapy of a transplanted pancreatic cancer model using meta-tetrahydroxyphenylchlorin (mTHPC). British Journal of Cancer, 76(6), 713 - 718.
    • Chang SC, Buonaccorsi GA, MacRobert AJ, Bown SG (1997). Interstitial photodynamic therapy in the canine prostate with disulfonated aluminum phthalocyanine and 5-aminolevulinic acid-induced protoporphyrin IX. Prostate, 32(2), 89 - 98.
    • Bech O, Phillips D, Moan J, MacRobert AJ (1997). A hydroxypyridinone (CP94) enhances protoporphyrin IX formation in 5-aminolaevulinic acid treated cells. Journal of Photochemistry and Photobiology B: Biology, 41(1-2), 136 - 144.
    • Jenkins MP, McEwan J, MacRobert AJ, Bishop CCR, Bown SG (1997). Photosensitisation with 5-ALA allows selective targeting of the arterial wall using photodynamic therapy. Lasers in Medical Science, 12(3), 290 - 290.
    • Scully AD, Ostler RB, Phillips KMS, Townsend P, O'Neil P, MacRobert AJ (1997). Application of fluorescence lifetime imaging microscopy to the investigation of intracellular PDT mechanisms. Bioimaging, (5), 9 - 18.
    • Jackson Z, Macrobert AJ, Meghji S, Henderson B, Wilson M (1997). Lethal photosensitisation of the hyphal form of Candida albicans.
    • Bhatti M, MacRobert A, Meghji S, Henderson B, Wilson M (1997). Effect of dosimetric and physiological factors on the lethal photosensitization of Porphyromonas gingivalis in vitro. Photochemistry and Photobiology, 65(6), 1026 - 1031.
    • Chang SC, MacRobert AJ, Porter JB, Bown SG (1997). The efficacy of an iron chelator (CP94) in increasing cellular protoporphyrin IX following intravesical 5-aminolaevulinic acid administration: An in vivo study. Journal of Photochemistry and Photobiology B: Biology, 38(2-3), 114 - 122.
    • Dhami S, Rumbles G, MacRobert AJ, Phillips D (1997). Comparative photophysical study of disulfonated aluminum phthalocyanine in unilamellar vesicles and leukemic K562 cells. Photochemistry and Photobiology, 65(1), 85 - 90.
    • (1997). Effect of environmental and physiological factors on the lethal photosensitisation of porphyromas gingivalis in vitro. Photochemistry and Photobiology, 65, 1026 - 1031.
    • Chang SC, Buonaccorsi G, MacRobert AJ, Bown SG (1997). 5-aminolevulinic acid (ALA)-induced protoporphyrin IX fluorescence and photodynamic effects in the rat bladder: An in vivo study comparing oral and intravesical ALA administration. Lasers in Surgery and Medicine, 20(3), 254 - 264.
    • Millson CE, Thurrell W, Buonaccorsi G, Wilson M, MacRobert AJ, Bown SG (1997). The effect of low-power laser light at different doses on gastric mucosa sensitized with methylene blue, haematoporphyrin derivative or toluidine blue. Lasers in Medical Science, 12(2), 145 - 150.

    1996

    • Chang SC, MacRobert AJ, Bown SG (1996). Biodistribution of protoporphyrin IX in rat urinary bladder after intravesical instillation of 5-aminolevulinic acid. The Journal of Urology, 155(5), 1744 - 1748.
    • Jackson Z, MacRobert AJ, Henderson B, Meghji S, Wilson M (1996). Susceptibility of Candida albicans to a light activated antimicrobial agent. Journal of Dental Research, 75(5), 1137 - 1137.
    • Millson CE, Wilson M, MacRobert AJ, Bedwell J, Bown SG (1996). The killing of Helicobacter pylori by low-power laser light in the presence of a photosensitiser. Journal of Medical Microbiology, 44(4), 245 - 252.
    • Ravi B, Regula J, Buonaccorsi GA, MacRobert AJ, Loh CS, Bown SG (1996). Sensitization and photodynamic therapy of normal pancreas, duodenum and bile ducts in the hamster using 5-aminolaevulinic acid. LASER MED SCI, 11(1), 11 - 21.
    • Chang SC, Buonaccorsi G, MacRobert A, Bown SG (1996). Interstitial and transurethral photodynamic therapy of the canine prostate using meso-tetra-(m-hydroxyphenyl) chlorin. International Journal of Cancer, 67(4), 555 - 562.
    • Fan KFM, Hopper C, Speight PM, Buonaccorsi G, MacRobert AJ, Bown SG (1996). Photodynamic therapy using 5-aminolevulinic acid for premalignant and malignant lesions of the oral cavity. Cancer, 78(7), 1374 - 1383.
    • Kleemann D, MacRobert AJ, Mentzel T, Speights PM, Bown SG (1996). Photodynamic therapy on the normal rabbit larynx with phthalocyanine and 5-aminolaevulinic acid induced protoporphyrin IX photosensitisation. British Journal of Cancer, 74(1), 49 - 58.
    • Mlkvy P, Messmann H, Pauer M, Stewart JCM, Millson CE, MacRobert AJ, Bown SG (1996). Distribution and photodynamic effects of meso-tetrahydroxyphenylchlorin (mTHPC) in the pancreas and adjacent tissues in the Syrian golden hamster. British Journal of Cancer, 73(12), 1473 - 1479.
    • Mlkvy P, Messmann H, Pauer M, Stewart JC, Millson CE, MacRobert AJ, Bown SG (1996). Distribution and photodynamic effects of meso-tetrahydroxyphenylchlorin (mTHPC) in the pancreas and adjacent tissues in the Syrian golden hamster.. Br J Cancer, 73(12), 1473 - 1479.
    • Chang SC, MacRobert AJ, Bown SG (1996). Biodistribution of protoporphyrin IX in rat urinary bladder after intravesical instillation of 5-aminolevulinic acid.. J Urol, 155(5), 1744 - 1748.
    • Chang SC, MacRobert AJ, Bown SG (1996). Photodynamic therapy on rat urinary bladder with intravesical instillation of 5-aminolevulinic acid: Light diffusion and histological changes. The Journal of Urology, 155(5), 1749 - 1753.
    • Chang SC, MacRobert AJ, Bown SG (1996). Photodynamic therapy on rat urinary bladder with intravesical instillation of 5-aminolevulinic acid: light diffusion and histological changes.. J Urol, 155(5), 1749 - 1753.
    • Scully AD, MacRobert AJ, Botchway S, O'Neil P, Parker AW, Ostler RBAPD (1996). Development of a laser-based fluorescence microscope with sub-nanosecond time resolution. Journal of Fluorescence, 6, 119 - 125.
    • Millson CE, Wilson M, MacRobert AJ, Bown SG (1996). Ex-vivo treatment of gastric Helicobacter infection by photodynamic therapy. Journal of Photochemistry and Photobiology B: Biology, 32(1-2), 59 - 65.
    • Nyamekye I, Buonaccorsi G, McEwan J, MacRobert A, Bown S, Bishop C (1996). Inhibition of intimal hyperplasia in balloon injured arteries with adjunctive phthalocyanine sensitised photodynamic therapy. European Journal of Vascular and Endovascular Surgery, 11(1), 19 - 28.
    • Chang SC, Buonaccorsi G, MacRobert AJ, Bown SG (1996). Interstitial photodynamic therapy of canine prostate with meso-tetra-(m-hydroxyphenyl)chlorin and 5-aminolaevulinic acid: A preliminary study.
    • Davies CL, Duffy PM, MacRobert AJ, Loizidou MC, Cooper AJ, Taylor I (1996). Localization of anthracycline accumulation in sensitive and resistant urothelial tumor cell lines. Cancer Detection and Prevention, 20(6), 625 - 633.
    • Loh CS, MacRobert AJ, Buonaccorsi G, Krasner N, Bown SG (1996). Mucosal ablation using photodynamic therapy for the treatment of dysplasia: An experimental study in the normal rat stomach. Gut, 38(1), 71 - 78.
    • Loh CS, MacRobert AJ, Buonaccorsi G, Krasner N, Bown SG (1996). Mucosal ablation using photodynamic therapy for the treatment of dysplasia: an experimental study in the normal rat stomach.. Gut, 38(1), 71 - 78.

    1995

    • Grant WE, Buonaccorsi G, Speight PM, MacRobert AJ, Hopper C, Bown SG (1995). The effect of photodynamic therapy on the mechanical integrity of normal rabbit carotid arteries.. Laryngoscope, 105(8 Pt 1), 867 - 871. doi:10.1288/00005537-199508000-00019
    • Kleemann D, MacRobert AJ, Mentzel T, Brown SG (1995). Experimental photodynamic therapy of the larynx using 5-aminolaevulinic acid.. Adv Otorhinolaryngol, 49, 36 - 38.
    • Mĺkvy P, Messmann H, Regula J, Conio M, Pauer M, Millson CE, MacRobert AJ, Bown SG (1995). Sensitization and photodynamic therapy (PDT) of gastrointestinal tumors with 5-aminolaevulinic acid (ALA) induced protoporphyrin IX (PPIX). A pilot study.. Neoplasma, 42(3), 109 - 113.
    • Regula J, MacRobert AJ, Gorchein A, Buonaccorsi GA, Thorpe SM, Spencer GM, Hatfield AR, Bown SG (1995). Photosensitisation and photodynamic therapy of oesophageal, duodenal, and colorectal tumours using 5 aminolaevulinic acid induced protoporphyrin IX--a pilot study.. Gut, 36(1), 67 - 75.
    • MacRobert AJ (1995). Photodynamic therapy using systemically administered 5-aminolaevulinic acid;. Trends in Photochemistry and Photobiology, 3, 403 - 408.
    • CHANG SC, MACROBERT AJ, BOWN SG (1995). THE BIODISTRIBUTION AND PHOTODYNAMIC EFFECT OF PROTOPORPHYRIN-IX IN RAT URINARY BLADDERS AFTER INTRAVESICAL INSTILLATION OF 5-AMINOLAEVULINIC ACID.
    • GRANT WE, HOPPER C, BUONACCORSI G, SPEIGHT PM, MACROBERT A, FAN K, BOWN SG (1995). PHOTODYNAMIC THERAPY OF ARTERIES - PRESERVATION OF MECHANICAL INTEGRITY.
    • NYAMEKYE I, MACROBERT A, BISHOP C, BOWN S (1995). Limitations of the rat carotid balloon de-endothelialization model in arterial photodynamic therapy: A study using 5-aminolaevulinic acid..
    • MILLSON C, WILSON M, MACROBERT A, THURRELL W, MILKVY P, DAVIES C, BOWN S (1995). LETHAL PHOTOSENSITISATION OF HELICOBACTER SPECIES.
    • Messmann H, Mlkvy P, Buonaccorsi G, Davies CL, MacRobert AJ, Bown SG (1995). Enhancement of photodynamic therapy with 5-aminolaevulinic acid-induced porphyrin photosensitisation in normal rat colon by threshold and light fractionation studies.. Br J Cancer, 72(3), 589 - 594.
    • Messmann H, Mlkvy P, Buonaccorsi G, Davies CL, MacRobert A, Bown SG (1995). Enhancement of Photodynamic Therapy with 5-Aminolevulinic Acid-Induced Porphyrin Photosensitization in Normal Rat Colon by Threshold and Light Fractionation Studies. British Journal of Cancer, 72(3), 589 - 594.
    • Grant WE, Buonaccorsi G, Speight PM, MacRobert AJ, Hopper C, Bown SG (1995). The Effect of Photodynamic Therapy on the Mechanical Integrity of Normal Rabbit Carotid Arteries. Laryngoscope, 105(8), 867 - 871.
    • Mlkvy P, Messmann H, Debinski H, Regula J, Conio M, MacRobert A, Spigelman A, Phillips R, Bown SG (1995). Photodynamic Therapy for Polyps in Familial Adenomatous Polyposis - A Pilot-Study. European Journal of Cancer, 31A(7-8), 1160 - 1165.
    • Anson K, Buonaccorsi G, Eddowes M, MacRobert A, Mills T, Watson G (1995). A Comparative Optical Analysis of Laser Side-Firing Devices - A Guide to Treatment. British Journal of Urology, 75(3), 328 - 334.
    • Nyamekye I, Anglin S, McEwan J, MacRobert A, Bown S, Bishop C (1995). Photodynamic Therapy of Normal and Balloon-Injured Rat Carotid Arteries Using 5-Amino-Levulinic Acid. Circulation, 91(2), 417 - 425.
    • CHANG SC, MACROBERT AJ, PORTER JB, BOWN SG (1995). APPLICATION OF 1,2-DIETHYL-3-HYDROXYPYRIDIN-4-ONE TO ENHANCE TISSUE SELECTIVITY FOR PHOTODYNAMIC THERAPY OF THE BLADDER.
    • MLKVY P, MESSMANN H, REGULA J, CONIO M, PAUER M, MILLSON CE, MACROBERT AJ, BOWN SG (1995). SENSITISATION AND PHOTODYNAMIC THERAPY OF OESOPHAGEAL, DUODENAL AND COLONIC TUMOURS WITH 5-AMINOLAEVULINIC ACID (ALA) INDUCED PROTOPORPHYRIN-IX (PPIX).
    • MLKVY P, MESSMANN H, STEWART JC, PAUER M, MILLSON CE, MACROBERT AJ, BOWN SG (1995). DISTRIBUTION AND PHOTODYNAMIC EFFECT OF META-TETRAHYDROXYPHENYLCHLORIN (MTHPC) IN THE PANCREAS AND ADJACENT TISSUES IN THE SYRIAN GOLDEN HAMSTERS.
    • MESSMANN H, MLKVY P, MONTAN S, WANG I, NILSSON A, SVANBERG K, SVANBERG S, MACROBERT AJ, BOWN SG (1995). ENDOSCOPIC FLUORESCENCE OF GASTROINTESTINAL NEOPLASIA AFTER SENSITISATION WITH 5-AMINOLAEVULINIC ACID (ALA) OR PHOTOFRIN.
    • MILLSON CE, BUONACCORSI G, MACROBERT AJ, MLKVY P, BOWN SG (1995). FLUORESCENCE TISSUE DISTRIBUTION OF METHYLENE BLUE USED FOR PHOTODYNAMIC THERAPY OF HELICOBACTER-PYLORI.
    • MESSMANN H, MLKVY P, DAVIES C, MACROBERT AJ, BOWN SG (1995). THRESHOLD EFFECTS OF PDT IN THE NORMAL RAT COLON WITH ALA PHOTOSENSITISATION.

    1994

    • Regula J, Ravi B, Bedwell J, MacRobert AJ, Bown SG (1994). Photodynamic therapy using 5-aminolaevulinic acid for experimental pancreatic cancer--prolonged animal survival.. Br J Cancer, 70(2), 248 - 254.
    • NYAMEKYE I, MCEWAN J, MACROBERT A, BISHOP C, BOWN S (1994). ADJUNCTIVE ARTERIAL INJURY AND PHOTODYNAMIC THERAPY WITH ALUMINIUM DISULPHONATED PHTHALOCYANINE INHIBITS INTIMAL HYPERPLASIA.
    • Ambroz M, MacRobert AJ, Morgan J, Rumbles G, Foley MSC, Philips D (1994). Time-Resolved Fluorescence Spectroscopy and Intracellular Imaging of Disulfonated Aluminum Phthalocyanine. Journal of Photochemistry and Photobiology B: Biology, 22(2), 105 - 117.
    • NYAMEKYE I, MCEWAN J, MACROBERT A, BISHOP C, BOWN S (1994). PHOTODYNAMIC THERAPY OF CONTRACTILE ARTERIAL SMOOTH MUSCLE CELLS INVIVO USING ALUMINIUM DISULPHONATED PHTHALOCYANINE - IMPLICATIONS FOR ANGIOPLASTY INDUCED INTIMAL HYPERPLASIA.
    • Grant WE, Speight PM, MacRobert AJ, Hopper C, Bown SG (1994). Photodynamic therapy of normal rat arteries after photosensitisation using disulphonated aluminium phthalocyanine and 5-aminolaevulinic acid.. Br J Cancer, 70(1), 72 - 78.
    • NYAMEKVE I, GRANT W, MACROBERT S, BOWN S, ADISESHIAH M, BISHOP C (1994). PHOTODYNAMIC TREATMENT OF NORMAL ARTERIES USING A NEW PHTHALOCYANINE AND 675-NM LASER-LIGHT. BRIT J SURG, 81(4), 618 - 619.
    • MACROBERT AJ, JUDD MD, REGULA J, LOH CS, BROWN SG (1994). FLUORESCENCE STUDIES OF 5-AMINOLEVULINIC ACID-INDUCED PROTOPORPHYRIN-IX AND SULFONATED ALUMINUM PHTHALOCYANINE TISSUE DISTRIBUTIONS.

    1993

    • Grant WE, Hopper C, Speight PM, Macrobert AJ, Bown SG (1993). Photodynamic therapy of malignant and premalignant lesions in patients with 'field cancerization' of the oral cavity. Journal of Laryngology and Otology, 107(12), 1140 - 1145. doi:10.1017/S0022215100125496
    • MACROBERT AJ, BEDWELL J, LOH CS, CHATLANI PT, BOWN SG (1993). COMPARISON OF ALUMINUM SULFONATED PHTHALOCYANINE WITH 5-AMINOLEVULINIC ACID-INDUCED PROTOPORPHYRIN-IX - TISSUE DISTRIBUTIONS, PHOTODAMAGE AND PHOTODEGRADATION.
    • BUONACCORSI GA, BURKE T, MACROBERT AJ, HILL PD, ESSENPREIS ME, MILLS TN (1993). A CYLINDRICALLY DISTRIBUTING OPTICAL-FIBER TIP FOR UNIFORM LASER ILLUMINATION OF HOLLOW ORGANS.
    • Smith SGT, Bedwell J, MacRobert AJ, Griffiths MH, Bown SG, Hetzel MR (1993). Experimental Studies to Assess the Potential of Photodynamic Therapy for the Treatment of Bronchial Carcinomas. Thorax, 48(5), 474 - 480.
    • Loh CS, MacRobert AJ, Bedwell J, Regula J, Krasner N, Bown SG (1993). Oral versus intravenous administration of 5-aminolaevulinic acid for photodynamic therapy.. Br J Cancer, 68(1), 41 - 51.
    • Grant WE, Hopper C, MacRobert AJ, Speight PM, Bown SG (1993). Photodynamic therapy of oral cancer: photosensitisation with systemic aminolaevulinic acid. The Lancet, 342(8864), 147 - 148.
    • Loh CS, Vernon D, MacRobert AJ, Bedwell J, Bown SG, Brown SB (1993). Endogenous Porphyrin Distribution Induced by 5-Aminolevulinic Acid in the Tissue Layers of the Gastrointestinal-Tract. Journal of Photochemistry and Photobiology B: Biology, 20(1), 47 - 54.
    • Bishop SM, Khoo BJ, MacRobert AJ, Simpson MSC, Phillips D, Beeby A (1993). Characterization of the Photochemotherapeutic Agent Disulphonated Aluminum Phthalocyanine and Its High-Performance Liquid Chromatographic Separated Components. Journal of Chromatography A, 646(2), 345 - 350. doi:10.1016/0021-9673(93)83347-U

    1992

    • Bremner JC, Adams GE, Pearson JK, Sansom JM, Stratford IJ, Bedwell J, Bown SG, MacRobert AJ, Phillips D (1992). Increasing the effect of photodynamic therapy on the RIF-1 murine sarcoma, using the bioreductive drugs RSU1069 and RB6145.. Br J Cancer, 66(6), 1070 - 1076.
    • Morgan J, MacRobert AJ, Gray AG, Huehns ER (1992). Use of Photosensitive, Antibody Directed Liposomes to Destroy Target Populations of Cells in Bone-Marrow - A Potential Purging Method for Autologous Bone-Marrow Transplantation. British Journal of Cancer, 65(1), 58 - 64.
    • SIMPSON MSC, BEEBY A, BISHOP SM, MACROBERT AJ, PARKER AW, PHILLIPS D (1992). TIME RESOLVED SPECTROSCOPIC STUDIES OF SULFONATED ALUMINUM PHTHALOCYANINE TRIPLET-STATES.
    • LOH CS, BEDWELL J, MACROBERT AJ, KRASNER N, PHILLIPS D, BOWN SG (1992). THE KINETICS OF 5-AMINOLEVULINIC ACID PHOTOSENSITIZATION IN THE RAT STOMACH.
    • MACROBERT AJ, PHILLIPS D (1992). FLUORESCENCE IMAGING IN PHOTODYNAMIC THERAPY.
    • MARKMILLER U, BECK OJ, BEDWELL J, BOWN SG, ENDERS S, GONNERT M, LUDWIG M, MACROBERT AJ, STUMMER W, UNSOLD E (1992). DISTRIBUTION OF ALUMINUM-PHTHALOCYANINE (ALS2PC) IN NORMAL AND NEOPLASTIC RABBIT BRAIN FOLLOWING STEREOTAXIC AND SYSTEMIC APPLICATION FOR PDT IN NEUROSURGERY.
    • CHATLANI PT, BEDWELL J, MACROBERT AJ, BOWN SG (1992). DISTRIBUTION AND PHOTODYNAMIC EFFECTS OF DI-SULFONATED AND TETRA-SULFONATED ALUMINUM PHTHALOCYANINES (ALS2PC AND ALS4PC) IN NORMAL AND NEOPLASTIC RAT COLON.
    • JUDD MD, BEDWELL J, MACROBERT AJ, BOWN SG (1992). COMPARISON OF THE DISTRIBUTION OF PHTHALOCYANINE AND ALA-INDUCED PORPHYRIN SENSITIZERS WITHIN THE RABBIT UTERUS.
    • BEEBY A, BISHOP SM, KHOO BJ, MACROBERT AJ, PHILLIPS D (1992). CHEMICAL AND SPECTROSCOPIC CHARACTERIZATION OF DISULFONATED ALUMINUM PHTHALOCYANINE.
    • Bedwell J, MacRobert AJ, Phillips D, Bown SG (1992). Fluorescence distribution and photodynamic effect of ALA-induced PP IX in the DMH rat colonic tumour model.. Br J Cancer, 65(6), 818 - 824.
    • Chatlani PT, Nuutinen PJ, Toda N, Barr H, MacRobert AJ, Bedwell J, Bown SG (1992). Selective necrosis in hamster pancreatic tumours using photodynamic therapy with phthalocyanine photosensitization.. Br J Surg, 79(8), 786 - 790.
    • MacRobert AJ, Phillips D (1992). Photodynamic Therapy. Chemistry & Industry, 1, 17 - 20.
    • Loh CS, Bedwell J, MacRobert AJ, Krasner N, Phillips D, Bown SG (1992). Photodynamic therapy of the normal rat stomach: a comparative study between di-sulphonated aluminium phthalocyanine and 5-aminolaevulinic acid.. Br J Cancer, 66(3), 452 - 462.

    1991

    • Barr H, Chatlani P, Tralau CJ, MacRobert AJ, Boulos PB, Bown SG (1991). Local eradication of rat colon cancer with photodynamic therapy: correlation of distribution of photosensitiser with biological effects in normal and tumour tissue.. Gut, 32(5), 517 - 523.
    • Ambroz M, Beeby A, MacRobert AJ, Simpson MSC, Svensen RK, Phillips D (1991). Preparative, Analytical and Fluorescence Spectroscopic Studies of Sulfonated Aluminum Phthalocyanine Photosensitizers. Journal of Photochemistry and Photobiology B: Biology, 9(1), 87 - 95.
    • Chatlani PT, Bedwell J, MacRobert AJ, Barr H, Boulos PB, Krasner N, Phillips D, Bown SG (1991). Comparison of distribution and photodynamic effects of di- and tetra-sulphonated aluminium phthalocyanines in normal rat colon.. Photochem Photobiol, 53(6), 745 - 751.
    • Bedwell J, Chatlani PT, MacRobert AJ, Roberts JE, Barr H, Dillon J, Bown SG (1991). Enhanced Tumor Selectivity of Photodynamic Therapy in the Rat Colon Using A Radioprotective Agent. Photochemistry and Photobiology, 53(6), 753 - 756.
    • Nuutinen PJ, Chatlani PT, Bedwell J, MacRobert AJ, Phillips D, Bown SG (1991). Distribution and photodynamic effect of disulphonated aluminium phthalocyanine in the pancreas and adjacent tissues in the Syrian golden hamster.. Br J Cancer, 64(6), 1108 - 1115.
    • Pope AJ, MacRobert AJ, Phillips D, Bown SG (1991). The detection of phthalocyanine fluorescence in normal rat bladder wall using sensitive digital imaging microscopy.. Br J Cancer, 64(5), 875 - 879.

    1990

    • Tralau CJ, Barr H, MacRobert AJ, Bown SG (1990). Relative merits of porphyrin and phthalocyanine sensitization for photodynamic therapy. In Kessel D (Ed.), Photodynamic Therapy of Neoplastic Disease (pp. 263 - 277). : CRC Press.
    • Bedwell J, Holton J, Vaira D, MacRobert AJ, Bown SG (1990). In vitro killing of Helicobacter pylori with photodynamic therapy.. Lancet, 335(8700), 1287 - .
    • Barr H, Tralau CJ, Boulos PB, MacRobert AJ, Krasner N, Phillips D, Bown SG (1990). Selective Necrosis in Dimethylhydrazine-Induced Rat Colon Tumors Using Phthalocyanine Photodynamic Therapy. Gastroenterology, 98(6), 1532 - 1537.
    • Pope AJ, Masters JRW, MacRobert AJ (1990). The Photodynamic Effect of A Pulsed Dye-Laser on Human Bladder-Carcinoma Cells-Invitro. Urological Research, 18(4), 267 - 270.
    • Barr H, MacRobert AJ, Tralau CJ, Boulos PB, Bown SG (1990). The significance of the nature of the photosensitizer for photodynamic therapy: quantitative and biological studies in the colon.. Br J Cancer, 62(5), 730 - 735.

    1989

    • Barr H, Boulos PB, MacRobert AJ, Tralau CJ, D PD, Bown SG (1989). Comparison of Lasers for Photodynamic Therapy with a Phthalocyanine Photosensitiser. Lasers in Medical Science, 4, 7 - 12.
    • Phillips D, MacRobert AJ (1989). Spectroscopic studies of photosensitisers and selectivity in photodynamic therapy. In Kotyk A, Skoda J, Paces V, Kostka V (Ed.), Highlights of Modern Biochemistry (pp. 1517 - 1525). : VSP Int. Science. Publishers, Zeist.
    • MacRobert AJ, Bown SG, Phillips D (1989). What are the Ideal Photoproperties for a Sensitizer. Ciba Foundation Symposia, 146, 4 - 16.
    • Chan WS, MacRobert AJ, Phillips D, Hart IR (1989). Use of Charge Coupled Device Camera for Imaging of Intracellular Phthalocyanines. Photochemistry and Photobiology, 50(5), 617 - 624.
    • Tralau CJ, Young AR, Walker NP, Vernon DI, MacRobert AJ, Brown SB, Bown SG (1989). Mouse skin photosensitivity with dihaematoporphyrin ether (DHE) and aluminium sulphonated phthalocyanine (AlSPc): a comparative study.. Photochem Photobiol, 49(3), 305 - 312.

    1988

    • Barr H, Tralau CJ, Macrobert AJ, Morrison I, Phillips D, Bown SG (1988). Fluorescence photometric techniques for determination of microscopic tissue distribution of phthalocyanine photosensitizers for photodynamic therapy. Lasers in Medical Science, 3(2), 81 - 86.

    1987

    • Barr H, Tralau CJ, Boulos PB, MacRobert AJ, Tilly R, Bown SG (1987). The contrasting mechanisms of colonic collagen damage between photodynamic therapy and thermal injury.. Photochem Photobiol, 46(5), 795 - 800.
    • Cross FW, Aldhahir RK, Dyer PE, MacRobert AJ (1987). Time-Resolved Photoacoustic Studies of Vascular Tissue Ablation at 3 Laser Wavelengths. Applied Physics Letters, 50(15), 1019 - 1021.
    • Tralau CJ, MacRobert AJ, Coleridge-Smith PD, Barr H, Bown SG (1987). Photodynamic therapy with phthalocyanine sensitisation: quantitative studies in a transplantable rat fibrosarcoma.. Br J Cancer, 55(4), 389 - 395.
    • Feldmann D, Kutzner J, Laukemper J, MacRobert S, Welge KH (1987). Mass Spectroscopic Studies of the ArF-Laser Photoablation of Polystyrene. Applied Physics B: Lasers and Optics, 44(2), 81 - 85.
    • Barr H, Tralau CJ, MacRobert AJ, Krasner N, Boulos PB, Clark CG, Bown SG (1987). Photodynamic therapy in the normal rat colon with phthalocyanine sensitisation.. Br J Cancer, 56(2), 111 - 118.
    • Barr H, Tralau CJ, MacRobert AJ, Morrison I, Phillips DABSG (1987). Barr H, Tralau CJ, MacRobert AJ, Morrison I, Phillips D and Bown SG (1988) Fluorescence Photometric Techniques for Determination of Microscopic Tissue Distribution of Phthalocyanine Photosensitizers for Photodynamic Therapy. Lasers in Medical Science, 3, 81 - 86.

    1986

    • HANCOCK G, HARRISON PD, MACROBERT AJ (1986). RATE-CONSTANT MEASUREMENT OF THE O(P-3)+CF2(X-APPROXIMATELY-1A1) REACTION. J CHEM SOC FARAD T 2, 82, 647 - 651.
    • Feldmann D, Kutzner J, Laukemper J, Preuss M, MacRobert AJ, Welge KH (1986). Laser VUV photoionisation mass spectrometry. Advances in Mass Spectrometry, B, 971 - 973.
    • Hancock G, Harrison PD, MacRobert AJ (1986). Rate-Constant Measurement of the O(P3)+CF2(X1A1) Reaction. Journal of the Chemical Society, Faraday Transactions 2: Molecular and Chemical Physics, 82, 647 - 651.

    1985

    • Clyne MAA, MacRobert AJ, Stief LJ (1985). Elementary Reactions of the NCl Radical .2. Kinetics of the NCl+ClO and NCl+NO Reactions. Journal of the Chemical Society, Faraday Transactions 2: Molecular and Chemical Physics, 81(JAN), 159 - 167.

    1984

    • Clyne MAA, MacRobert AJ, Murrells TP, Stief LJ (1984). Kinetics of the Reactions of Atomic Chlorine with H2S, HS and OCS. Journal of the Chemical Society, Faraday Transactions 2: Molecular and Chemical Physics, 80, 877 - 886.
    • Ashfold MNR, Atkins CG, Hancock G, MacRobert AJ (1984). Infrared Photochemistry with Shaped Laser-Pulses. Israel Journal of Chemistry, 24(3), 197 - 203.
    • Hancock G, Ketley GW, MacRobert AJ (1984). CHF(X1A') Radical Kinetics .2. Reaction with O-Atoms and N-Atoms. Journal of Physical Chemistry, 88(10), 2104 - 2109.
    • Hancock G, Ketley GW, MacRobert AJ (1984). CHF(X̃A′) radical kinetics. 2. Reaction with O and N atoms. Journal of Physical Chemistry, 88(10), 2104 - 2109.

    1983

    • Beresford JR, Hancock G, MacRobert AJ, Catanzarite J, Radhakrishnan G, Reisler H, Wittig C (1983). Energy Distributions in the CN (X2Sigma+) Fragment from Infrared Multiple-photon Dissociation of CF3CN. A Comparison Between Experimental Results and the Predictions of Statistical-Theories. Faraday Discussions, (75), 211 - 222.
    • Clyne MAA, MacRobert AJ, Brunning J, Cheah CT (1983). Kinetics of Metastable Singlet NCl Radicals. Journal of the Chemical Society, Faraday Transactions 2: Molecular and Chemical Physics, 79, 1515 - 1524.
    • HANCOCK G, KETLEY GW, MACROBERT AJ, MCKENDRICK KG (1983). KINETIC-STUDIES OF CHF AND NCO RADICALS USING LASER-INDUCED FLUORESCENCE. B SOC CHIM BELG, 92(6-7), 638 - 638.
    • Hancock G, MacRobert AJ (1983). Quantitative and Separate Fluence and Intensity Dependences of Infrared Multiple-Photon Absorption in SF6. Chemical Physics Letters, 101(3), 312 - 316.
    • Clyne MAA, MacRobert AJ (1983). Elementary reactions of the NCl radical: Part 1. - Rate constants for the reactions NCl + NCl → N + 2Cl and O + NCl → NO + Cl. Journal of the Chemical Society, Faraday Transactions 2: Molecular and Chemical Physics, 79(2), 283 - 293. doi:10.1039/F29837900283

    1981

    • Clyne MAA, MacRobert AJ (1981). Kinetic-Studies of Free-Radical Reactions by Mass-Spectrometry .2. the Reactions of SO+ClO, SO+OclO and SO+BrO. International Journal of Chemical Kinetics, 13(2), 187 - 197.

    1980

    • Clyne MAA, MacRobert AJ (1980). Kinetic-Studies of Free-Radical Reactions by Mass-Spectrometry .1. Reactions SO+NO2 and ClO+NO. International Journal of Chemical Kinetics, 12(2), 79 - 96.

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