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Third of over 75s unaware they have chronic kidney disease

Over one-third of people aged over 75 show evidence of having severe chronic kidney disease, according to research from UCL published this week in the latest NHS Digital Health Survey for England. By comparison, only 5 per cent of adults of that age reported that they had been diagnosed with chronic kidney disease by a doctor.

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Drug lowers deadly Huntington’s disease protein

The first drug targeting the cause of Huntington’s disease was safe and well-tolerated in its first human trial led by UCL scientists. It successfully lowered the level of the harmful huntingtin protein in the nervous system.

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Psychosis incidence highly variable internationally

Rates of psychosis can be close to eight times higher in some regions compared to others, finds a new study led by researchers at UCL, King’s College London and the University of Cambridge.

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Children with mental health problems more likely to be out of work by 55

Physical and mental illness at younger ages can have a significant impact on people’s prospects of being in employment in later life, according to two reports from the International Longevity Centre (ILC-UK) and the renEWL research team based at UCL.

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Rising levels of HIV drug resistance

HIV drug resistance is approaching and exceeding 10% in people living with HIV who are about to initiate or reinitiate first-line antiretroviral therapy, according to a new study led by researchers at UCL and the World Health Organization (WHO).

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Ultrasound imaging needle to transform heart surgery

Heart tissue can be imaged in real-time during keyhole procedures using a new optical ultrasound needle developed by researchers at UCL and Queen Mary University of London (QMUL).

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Marriage may help stave off dementia

Marriage may lower the risk of developing dementia, concludes a UCL-led synthesis of the available evidence published online in the Journal of Neurology Neurosurgery & Psychiatry.

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Avatar therapy to reduce auditory hallucinations for people with schizophrenia

An experimental therapy which involves a face-to-face discussion between a person with schizophrenia and an avatar representing their auditory hallucination may help reduce symptoms, when provided alongside usual treatment, according to a study published in The Lancet Psychiatry journal.

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Gastric acid suppressant lansoprazole may target tuberculosis

A cheap and widely used drug, used to treat conditions such as heartburn, gastritis and ulcers, could work against the bacteria that cause tuberculosis (TB), according to new research from UCL and the London School of Hygiene & Tropical Medicine.

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Austerity linked to 120,000 extra deaths in England

Health and social care spending cuts since 2010 are linked to nearly 120,000 excess deaths in England, with the over 60s and care home residents most affected, finds new UCL research.

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Improving clinical trials with machine learning

Machine learning could improve our ability to determine whether a new drug works in the brain, potentially enabling researchers to detect drug effects that would be missed entirely by conventional statistical tests, finds a new UCL study published today in Brain.

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Society's excluded people ten times more likely to die early

People excluded from mainstream society in high-income countries have a tenfold increased risk of early death, according to research from UCL, homeless health charity Pathway and an international team of experts.

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