Reta Lila Weston Institute
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Dr Roberto Simone



Roberto Simone, PhD
Postdoctoral Research Fellow

Roberto Simone
Born in Italy, Roberto obtained an MSc degree in Biological Sciences from University  “La Sapienza” of Rome in 2003 where he spent 2 years in the laboratory of Prof. Irene Bozzoni, working on the biogenesis of small nucleolar RNAs in yeast, a peculiar class of ncRNAs involved in the processing and post-transcriptional methylation mainly of ribosomal transcripts.  He moved to Trieste where he did his PhD in Structural and Functional Genomics in the group of Mouse Molecular Neurobiology of Prof. Stefano Gustincich at International School of Advanced Studies (ISAS), working on single-cell gene espression analysis and mouse whole-transcriptome promoters analysis of two neuronal populations (A9-A10) differently affected in Parkinson’s disease. From 2006 to 2007 he worked at RIKEN Genome Science Laboratory in Tokyo with Dr. Piero Carninci and Charles Plessy where he developed a new sequencing–based approach (nanoCAGE) for measuring the position and the level of expression of all transcripts along the mouse genome in an unbiased way.  Roberto joined the RLWI in 2010 as a Postdoctoral Research Associate to investigate the specific effects of the inversion and of different genomic contexts to the transcriptional and splicing regulation of human MAPT gene, whose alterations have been associated to the development of many different neurodegenerative conditions.  
Tel:   +44-20-7679 4032 (Internal: 24032)
Fax:   +44-20-7278 4993
Email: r.simone[at]ucl.ac.uk
 

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