Infection, Immunology & Inflammation
The Infection, Immunology and Inflammation (III) Theme is a major grouping of cross-disciplinary expertise that brings together around 250 group leaders and post-doctoral researchers from across UCL.
By working together, UCL III researchers are increasing our understanding of diseases, such as HIV, TB, malaria, asthma, arthritis, and cancer. This cross-disciplinary culture also provides an excellent training environment for PhD students and post-doctoral scientists.
The UCL III community comes together once a year for the III Symposium, which showcases research activity and stimulates new collaborations.
Examples of Research
Professor Greg Towers has shown that blocking HIV infection by ‘uncloaking’ the virus particles may provide a new way of preventing infection. This work required expertise from several disciplines including virology, immunology and chemistry.
Professor Ali Zumla is leading studies to develop new diagnostic tools and treatments for tuberculosis; work that involves biochemistry, cell biology, clinical trials expertise and international collaborations.
Aging immune system
Professor Arne Akbar has developed new ways to monitor changes in the aging immune system and is interested in how older people respond to infection and inflammation. This work requires collaboration across the III Theme, with partnerships in clinical and basic biology as well as industry collaborations.
Other areas of focus across the Theme include:
- Bacterial infections (e.g.TB, Staph aureas), antimicrobial resistance
- Viruses (e.g. HIV, VZV), anti-viral immunity, and the development of new anti-viral drugs and diagnostics
- Parasitic diseases (e.g. malaria)
- Infectious diseases in children
- Bacterial and viral disease latency (i.e. periods of dormancy) and reactivation
- Lung infections and lung inflammation
- Rheumatic and autoimmune diseases such as rheumatoid arthritis and diabetes
- The effect of aging on the immune system
- Cancer immunology and immunotherapy
and computational studies of the immune response (which may help manage disease
in the future).
Below is a list of researchers who are currently working in the field at UCL. Click on their names to find their contact details and more information about their work.
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