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Children with mental health problems more likely to be out of work by 55

Physical and mental illness at younger ages can have a significant impact on people’s prospects of being in employment in later life, according to two reports from the International Longevity Centre (ILC-UK) and the renEWL research team based at UCL.

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Improving clinical trials with machine learning

Machine learning could improve our ability to determine whether a new drug works in the brain, potentially enabling researchers to detect drug effects that would be missed entirely by conventional statistical tests, finds a new UCL study published today in Brain.

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Sex differences important for medical research

The sex of animals frequently has an effect in biomedical research and therefore should be considered in scientific studies, according to UCL scientists.

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Type 2 diabetes genetic mapping identifies new ‘loci’

Scientists are closer to understanding the genetic causes of type 2 diabetes by identifying 111 new chromosome locations (‘loci’) on the human genome that indicate susceptibility to the disease, according to a UCL-led study in collaboration with Imperial College London.

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How gut bacteria change cancer drug activity

The activity of cancer drugs changes depending on the types of microbes living in the gut, according to a UCL-led study into how nematode worms and their microbes process drugs and nutrients.

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UCL part of new £100 million Rosalind Franklin Institute

UCL is involved in the Rosalind Franklin Institute (RFI) – a major new £100 million investment by the government into the development of an innovative multi-disciplinary science and technology research centre.

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'Brute force' can overcome antibiotic resistance

Antibiotics can still kill drug-resistant bacteria if they 'push' hard enough into bacterial cells, finds new UCL-led research funded by the Engineering and Physical Sciences Research Council.

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Light therapy effectively treats early prostate cancer

A new non-surgical treatment for low-risk prostate cancer can effectively kill cancer cells while preserving healthy tissue, reports a new UCL-led phase III clinical trial in 413 patients. The trial was funded by STEBA Biotech which holds the commercial license for the treatment.

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Pain sensors specialised for specific sensations

Many pain-sensing nerves in the body are thought to respond to all types of ‘painful events’, but new UCL research in mice reveals that in fact most are specialised to respond to specific types such as heat, cold or mechanical pain.

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‘Middle England’ faces lowest psychosis risk

The risk of developing a psychotic disorder such as schizophrenia is highest for young people, men, ethnic minorities and people living in urban areas and poorer neighbourhoods, finds a new study by UCL and the University of Cambridge.

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UCL receives largest share of NHS research funding

UCL’s three biomedical research centres (BRCs) have won more than £167 million in funding from the National Institute for Health Research (NIHR) to further world-leading biomedical research conducted with partner hospitals. UCL has received more funding than any other UK university, followed by King's College London and Oxford University, which received £133m and £127m respectively.

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Science begins in the new Francis Crick Institute building

The first scientists have moved into the new £650 million Francis Crick Institute building in London and are starting work in their purpose-built labs. Next to St Pancras station and the British Library, the Crick will be the biggest biomedical research institute under one roof in Europe.

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Refining the genetic causes of schizophrenia

An international study involving UCL has made advances in understanding the ways in which genetic risk factors alter gene function in schizophrenia.

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Heart drug could reduce diabetes related blindness

Researchers at UCL and Queen’s University Belfast have discovered that a drug originally developed to treat cardiovascular disease has the potential to reduce diabetes related blindness.

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Cancer drugs could target autoimmune diseases

Drugs currently being trialled in cancer patients have been used to successfully target an autoimmune condition in mice at UCL and King’s College London.

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New team to develop radiotherapies that target cancer more effectively

Safer precision radiotherapies that will be able to cure more cancers with fewer side-effects will be available within five years under ambitious new plans for research and treatment at the UCL Cancer Institute and University College London Hospitals (UCLH) NHS Foundation Trust.

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