Proteomics plays a central role in post-genomic molecular biology, biomedicine and discovery of biomarkers and drug targets. In the past decade, Mass Spectrometry (MS) has emerged as the dominant technology for in-depth characterisation of the protein components of biological systems. Because of its unparalleled ability to acquire high content quantitative information about biological samples of high complexity, MS is a major driving force behind proteomics science.
co-ordinates existing proteomics activities at UCL and is a multi-site proteomics/mass spectrometry centre that now links the current UCL proteomics groups. It provides expertise and facilities in cutting-edge proteomics research.
The aims of UCL Proteomics are to:
• Provide an interface for potential users of proteomic technologies to get information on matters such as availability of facilities, expertise, typical sample requirements, news, publications, the strengths of the different types of MS equipment and proteomics strategies
• Provide an academic environment for maintaining and developing proteomics knowledge and expertise
• Coordinate collaboration amongst various groups
• Provide new information and guidance from the Human Proteome Organization and other national and international proteomics organizations
• Provide educational activities
UCL Proteomics supports state-of-the-art mass spectrometry, quantitative protein profiling, shotgun proteomics, MS tissue imaging and metabolomics expertise. In addition, UCL Proteomics is experienced in building the databases needed to effectively analyse, archive, and interpret the large amounts of protein data that are produced by proteomics experiments.
consists of four research groups:
Prof J. Godovac-Zimmermann's Rayne Institute Molecular Cell Dynamics Group
Prof J. Hsuan's RF CBS Proteomics Unit
Dr K. Mills' ICH Mass Spectrometry Group
Dr J. Timms' IfWH Cancer Proteomics Group