UCL School of Pharmacy
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UCL School of Pharmacy
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Understanding the mechanisms of hyposmia in a novel model of early stage Parkinson's Disease (ESPD) and its reversal by exendin-4

Project description

Applications are invited for a 3 year funded PhD studentship in the laboratories of Dr. Andy Constanti and Dr. Peter Whitton at The UCL School of Pharmacy. The work in our laboratories is currently focused on investigating a new model of early stage Parkinson’s Disease (ESPD) with a particular focus on the mechanisms responsible for hyposmia, one of the so-called early ‘pre-motor’ symptoms exhibited by many PD patients and its reversal by exendin-4, a recently introduced anti-diabetic drug, also currently being evaluated in clinical trials as a novel treatment for PD. The proposed project will involve mainly neurochemical, histological and possibly also intracellular in vitro electrophysiological techniques, therefore will involve a variety of disciplines including neuropharmacology, immunocytochemistry and neurophysiology. The project will allow development of skills in these areas as appropriate. The successful candidate will work in an established laboratory currently funded by the Cure Parkinson’s Trust. The candidate will also have access to specialized training courses as required.

Further information

Applications are sought from candidates with a first or upper second class honours degree in Neuroscience, Pharmacology, Physiology, Biology, Biochemistry, Pharmacy or an equivalent subject.  An MSc in Neuroscience or Pharmacology or a relevant industrial placement of 6 months or more are desirable though not a requirement.

This studentship is limited to students with Home/ EU tuition fee status and it covers the tuition fees and a maintenance stipend for three years. For 2012/13 the stipend rate is £15,590. The start date of the studentship is flexible but we would ideally wish to make an appointment to start from 8 April 2013 at the latest. 

Informal enquiries may be addressed to

Dr Andy Constanti:

 http://iris.ucl.ac.uk/iris/browse/profile?upi=ACONS16

or Dr Peter Whitton:

 https://iris.ucl.ac.uk/iris/browse/profile?upi=PWHIT00

Applications must include CV, personal statement plus the names of two referees and should be sent to Victor Diran.

Application closing date is 22 March 2013.

The UCL School of Pharmacy is committed to equality of opportunity and selection on merit.

Page last modified on 28 feb 13 17:18