Early quantitative and qualitative results from the ProDEED trial
Monday, 21st March 2011
1pm - 2pm (sandwiches from 12.45 onwards)
Seminar Room, PCPH, Upper 3rd Floor, Royal Free Campus
Marta Buszewicz and Madeleine Hutson
Introduction: Care for people with long-term depression is
often inconsistent, with significant psychological, physical and
and high financial costs.
Aims of the ProCEED study (Pro-active care and its
evaluation for enduring depression):
(1) To establish whether structured, pro-active care of primary
care patients with chronic depression leads to cost-effective
in medical and social outcomes compared with usual general
practitioner (GP) care.
(ii) To assess whether training general practice nurses leads to
improved assessment and follow-up of patients with chronic
and provides on-going skills in this area
Methods: Recruitment was from 42 UK general practices. Eligible
participants had chronic major or recurrent major depression or
confirmed by Composite International Diagnostic Interview (CIDI)
and scored 14 or above on the Beck Depression Inventory (BDI-II).
Consented participants were randomised to GP treatment as usual
(controls) or the practice nurse intervention.
Qualitative in-depth interviews were conducted with 15/42 practice
nurses and 26/282 Intervention patients
Results: The early trial results are promising and show a positive effect
of the nurse intervention on the BDI-II results and a
significantly positive effect
on the WASAS questionnaire, which measures how people are
functioning in their lives. We are still awaiting the health
In the qualitative study most intervention patients reported
positive impacts - both on mental health and other areas of their
All nurses interviewed reported improved confidence in dealing
with mental health issues and most reported a beneficial impact on
their clinical skills.
Conclusions: The trial results should have significant implications for the
management of depression in primary care and the potential role of
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by Orla O'Donnell