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Maternal Mortality
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Selection Bias

PRAiS2 work published in the Annals of Thoracic Surgery

3 May 2017

The PRAiS2 project, led by Principal Investigator Christina Pagel, built on the earlier PRAiS project, which developed a risk-adjustment model equation for mortality after paediatric cardiac surgery. The PRAiS (Partial Risk Adjustment in Surgery) model, and computer software that implements it, uses risk factors to estimate the chance of death within 30 days of surgery. This helps clinical teams to take account of the types of patient they have operated upon when studying their recent survival data.

The PRAiS2 project updated the original PRAiS model with new comorbid risk factors, an increased amount of diagnostic information included, and an improved treatment of weight and age in the model. A website was also developed during the project, which includes interactive tools and a short video, to help families, the public and the media interpret published survival data for children having heart surgery.

The team at CORU worked with clinicians from across the UK, experts in clinical coding and communication of risk and the charities Children’s Heart Federation and Sense about Science throughout the project.

The work has been published online by the Annals of Thoracic Surgery as 3 joint papers, to be accompanied by an editorial when published in print in July 2017. The three open access papers detailing the model update process, development of the new comorbid risk factors, and the development of online resources to explain risk-adjusted survival can be found on the Annals of Thoracic Surgery website.

Funding acknowledgement

This project was funded by the National Institute for Health Research Health Services and Delivery Research Programme (project number 14/19/13).

Department of Health disclaimer

The views and opinions expressed therein are those of the authors and do not necessarily reflect those of the Health Services and Delivery Research Programme, NIHR, NHS or the Department of Health.