Prof Anthony Dickenson

Photo

Personal Profile

Name: Anthony Dickenson Email: anthony.dickenson@ucl.ac.uk
Title: Prof Tel: 020 7679 3742
Department: Neuroscience, Physiology & Pharmacology Fax: 020 7679 7298
Position: Professor of Neuropharmacology Address: Pharmacology, Medical Sciences Building, UCL South Cloisters, Gower St, London, WC1E 6BT
Research Domain: Basic Life Sciences, Experimental Medicine, Neuroscience, Personalised Medicine Web Page: Personal Web Page

Profile

Research Description

Our research has been based on understanding the transmission and control of pain related to improving its treatment, either through better knowledge of mechanisms or characterization of novel targets. The approach has been to understand how pain changes the nervous system.The groupI have studied how neuronal systems alter in patho-physiological states and how novel and licensed drugs produce their effects on pain processes. We have made many major advances in this area and the aim has been to translate the basic research into clinical applications.

Early on we described Diffuse Noxious Inhibitory controls (DNIC) and subsequently provided a detailed description of their neural basis. DNIC are used as a possible diagnostic in chronic pain patients. At UCL, our original pioneering work on the neuronal actions of opioid receptors lead to major advances in opioid function, the idea of pre-emptive analgesia and other important clinical translations. We were the first group to show the NMDA receptor mediation of wind-up, then its role in persistent pain. This and our continuing work on central hyperexcitability has been seminal in understanding of pain in animals and humans.
We further initiated some of the very first studies on the pharmacology of the developing spinal cord related to paediatric pain control. We have studied a number of novel mediators ranging from nitric oxide, adenosine, nicotinic ligands and newer opioids. Assessment of drug combinations has also guided clinical practice.

More recently, we have taken our work on the plasticity of spinal signalling after inflammation to other pain states to examine changes after nerve injury and adapted and further developed a rodent model of bone cancer, all of which have informed clinical practice. At the same time we have some very fruitful collaborations with molecular groups. We have provided evidence for roles of targets that include sodium channels found in peripheral neurons and central G-protein linked receptors within integrated systems using levels and ranges of stimuli that cannot be assessed by behavioural approaches. Further advances using pharmacological tools are exemplified by functional identification of roles for Kv7/M and other potassium channels that could be novel pain targets. Ongoing active studies include assessing tissue specific knock-outs with Prof J Wood, and our original extensive work on calcium channel function in pain has lead to international collaborations on the roles of splice variants and over-expressing of calcium channel subunits. Finally, in the last 2 years, our original studies with novel techniques on spinal neurones that project to the brain and engage descending brainstem serotonergic influences to the cord to enhance spinal excitability have had major implications for the understanding how pain shapes emotional changes. We have shown the integrity of this pathway is a crucial determinant of both the abnormal neuronal and behavioural manifestation of nerve injury. This pathway also has a major bearing on efficacy of drugs used in neuropathic pain and has been verified in humans through imaging and clinical trials of novel analgesics.


Research Activities

Bioinformatics - prediction of protein functions and functional networks

Plasticity in pain mechanisms

molecular neurobiology

Education Description

UCL Collaborators

Prof David Jones; Dr Mike Hubank; Dr Andrew Martin; Prof Steve Hunt; Prof Christine Orengo

External Collaborators

Publications

    2014

    • Bannister K, Lee YS, Goncalves L, Porreca F, Lai J, Dickenson AH (2014). Neuropathic plasticity in the opioid and non-opioid actions of dynorphin A fragments and their interactions with bradykinin B2 receptors on neuronal activity in the rat spinal cord.. Neuropharmacology, 85C, 375 - 383. doi:10.1016/j.neuropharm.2014.06.005
    • Falk S, Patel R, Heegaard A, Mercadante S, Dickenson AH (2014). Spinal neuronal correlates of tapentadol analgesia in cancer pain: A back-translational approach.. Eur J Pain, , - . doi:10.1002/ejp.530
    • Falk S, Dickenson AH (2014). Pain and Nociception: Mechanisms of Cancer-Induced Bone Pain.. J Clin Oncol, , - . doi:10.1200/JCO.2013.51.7219
    • Patel R, Goncalves L, Newman R, Jiang FL, Goldby A, Reeve J, Hendrick A, Teall M, Hannah D, Almond S, Brice N, Dickenson AH (2014). Novel TRPM8 Antagonist Attenuates Cold Hypersensitivity Following Peripheral Nerve Injury in Rats.. J Pharmacol Exp Ther, , - . doi:10.1124/jpet.113.211243
    • Rahman W, Dickenson AH (2014). Pain: nonmalignant disease.. Curr Opin Support Palliat Care, , - . doi:10.1097/SPC.0000000000000052
    • Thakur M, Dickenson AH, Baron R (2014). Osteoarthritis pain: nociceptive or neuropathic?. Nat Rev Rheumatol, , - . doi:10.1038/nrrheum.2014.47
    • Gilron I, Dickenson AH (2014). Emerging drugs for neuropathic pain.. Expert Opin Emerg Drugs, , - . doi:10.1517/14728214.2014.915025

    2013

    • Eijkelkamp N, Linley JE, Torres JM, Bee L, Dickenson AH, Gringhuis M, Minett MS, Hong GS, Lee E, Oh U, Ishikawa Y, Zwartkuis FJ, Cox JJ, Wood JN (2013). A role for Piezo2 in EPAC1-dependent mechanical allodynia.. Nat Commun, 4, 1682 - . doi:10.1038/ncomms2673
    • Currie GL, Delaney A, Bennett MI, Dickenson AH, Egan KJ, Vesterinen HM, Sena ES, Macleod MR, Colvin LA, Fallon MT (2013). Animal models of bone cancer pain: systematic review and meta-analyses.. Pain, 154(6), 917 - 926. doi:10.1016/j.pain.2013.02.033
    • Burnham LJ, Dickenson AH (2013). The antinociceptive effect of milnacipran in the monosodium iodoacetate model of osteoarthritis pain and its relation to changes in descending inhibition.. J Pharmacol Exp Ther, 344(3), 696 - 707. doi:10.1124/jpet.112.199489
    • Dickenson AH, Kehlet H (2013). Can we stop pain before it starts?. Pain, , - . doi:10.1016/j.pain.2013.11.016
    • Baron R, Hans G, Dickenson AH (2013). Peripheral input and its importance for central sensitization.. Ann Neurol, 74(5), 630 - 636. doi:10.1002/ana.24017
    • Lana B, Schlick B, Martin S, Pratt WS, Page KM, Goncalves L, Rahman W, Dickenson AH, Bauer CS, Dolphin AC (2013). Differential up-regulation in DRG neurons of an α2δ-1 splice variant with a lower affinity for gabapentin after peripheral sensory nerve injury.. Pain, , - . doi:10.1016/j.pain.2013.12.001
    • Hirsch SJ, Dickenson AH (2013). Morphine sensitivity of spinal neurons in the chronic constriction injury neuropathic rat pain model.. Neurosci Lett, , - . doi:10.1016/j.neulet.2013.10.007
    • Dickenson AH (2013). Commentary on: Opioid and noradrenergic contributions of tapentadol in experimental neuropathic pain.. Neurosci Lett, , - . doi:10.1016/j.neulet.2013.09.069
    • Gilron I, Jensen TS, Dickenson AH (2013). Combination pharmacotherapy for management of chronic pain: from bench to bedside.. Lancet Neurol, , - . doi:10.1016/S1474-4422(13)70193-5
    • Patel R, Bauer CS, Nieto-Rostro M, Margas W, Ferron L, Chaggar K, Crews K, Ramirez JD, Bennett DL, Schwartz A, Dickenson AH, Dolphin AC (2013). α2δ-1 Gene Deletion Affects Somatosensory Neuron Function and Delays Mechanical Hypersensitivity in Response to Peripheral Nerve Damage.. J Neurosci, 33(42), 16412 - 16426. doi:10.1523/JNEUROSCI.1026-13.2013
    • Rahman W, Dickenson AH (2013). Voltage gated sodium and calcium channel blockers for the treatment of chronic inflammatory pain.. Neurosci Lett, , - . doi:10.1016/j.neulet.2013.08.004
    • Tesfaye S, Boulton AJ, Dickenson AH (2013). Mechanisms and management of diabetic painful distal symmetrical polyneuropathy.. Diabetes Care, 36(9), 2456 - 2465. doi:10.2337/dc12-1964
    • Sikandar S, Dickenson AH (2013). II. No need for translation when the same language is spoken.. Br J Anaesth, 111(1), 3 - 6. doi:10.1093/bja/aet210
    • Sikandar S, Ronga I, Iannetti GD, Dickenson AH (2013). Neural coding of nociceptive stimuli-from rat spinal neurones to human perception.. Pain, , - . doi:10.1016/j.pain.2013.03.041
    • Sikandar S, Patel R, Patel S, Sikander S, Bennett DL, Dickenson AH (2013). Genes, molecules and patients--emerging topics to guide clinical pain research.. Eur J Pharmacol, 716(1-3), 188 - 202. doi:10.1016/j.ejphar.2013.01.069

    2012

    • O'Neill J, Brock C, Olesen AE, Andresen T, Nilsson M, Dickenson AH (2012). Unravelling the mystery of capsaicin: a tool to understand and treat pain.. Pharmacol Rev, 64(4), 939 - 971. doi:10.1124/pr.112.006163
    • Gonçalves L, Dickenson AH (2012). Asymmetric time-dependent activation of right central amygdala neurones in rats with peripheral neuropathy and pregabalin modulation.. Eur J Neurosci, 36(9), 3204 - 3213. doi:10.1111/j.1460-9568.2012.08235.x
    • Sikandar S, Bannister K, Dickenson AH (2012). Brainstem facilitations and descending serotonergic controls contribute to visceral nociception but not pregabalin analgesia in rats.. Neurosci Lett, 519(1), 31 - 36. doi:10.1016/j.neulet.2012.05.009
    • Neziri AY, Dickenmann M, Scaramozzino P, Andersen OK, Arendt-Nielsen L, Dickenson AH, Curatolo M (2012). Effect of intravenous tropisetron on modulation of pain and central hypersensitivity in chronic low back pain patients.. Pain, 153(2), 311 - 318. doi:10.1016/j.pain.2011.10.008
    • Minett MS, Nassar MA, Clark AK, Passmore G, Dickenson AH, Wang F, Malcangio M, Wood JN (2012). Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons.. Nat Commun, 3, 791 - . doi:10.1038/ncomms1795
    • Thakur M, Rahman W, Hobbs C, Dickenson AH, Bennett DL (2012). Characterisation of a peripheral neuropathic component of the rat monoiodoacetate model of osteoarthritis.. PLoS One, 7(3), e33730 - . doi:10.1371/journal.pone.0033730
    • Sikandar S, Dickenson AH (2012). Visceral pain: the ins and outs, the ups and downs.. Curr Opin Support Palliat Care, 6(1), 17 - 26. doi:10.1097/SPC.0b013e32834f6ec9
    • Passmore GM, Reilly JM, Thakur M, Keasberry VN, Marsh SJ, Dickenson AH, Brown DA (2012). Functional significance of M-type potassium channels in nociceptive cutaneous sensory endings.. Front Mol Neurosci, 5, 63 - . doi:10.3389/fnmol.2012.00063

    2011

    • Marchand F, D'Mello R, Yip PK, Calvo M, Muller E, Pezet S, Dickenson AH, McMahon SB (2011). Specific involvement of atypical PKCζ/PKMζ in spinal persistent nociceptive processing following peripheral inflammation in rat.. Mol Pain, 7, 86 - . doi:10.1186/1744-8069-7-86
    • Dickenson AH, Baron R (2011). Descending controls: insurance against pain?. Pain, 152(12), 2677 - 2678. doi:10.1016/j.pain.2011.07.003
    • Sikandar S, Dickenson AH (2011). Pregabalin modulation of spinal and brainstem visceral nociceptive processing.. Pain, 152(10), 2312 - 2322. doi:10.1016/j.pain.2011.06.020
    • Neziri AY, Scaramozzino P, Andersen OK, Dickenson AH, Arendt-Nielsen L, Curatolo M (2011). Reference values of mechanical and thermal pain tests in a pain-free population.. Eur J Pain, 15(4), 376 - 383. doi:10.1016/j.ejpain.2010.08.011
    • D'Mello R, Marchand F, Pezet S, McMahon SB, Dickenson AH (2011). Perturbing PSD-95 interactions with NR2B-subtype receptors attenuates spinal nociceptive plasticity and neuropathic pain.. Mol Ther, 19(10), 1780 - 1792. doi:10.1038/mt.2011.42
    • Rahman W, Bannister K, Bee LA, Dickenson AH (2011). A pronociceptive role for the 5-HT2 receptor on spinal nociceptive transmission: an in vivo electrophysiological study in the rat.. Brain Res, 1382, 29 - 36. doi:10.1016/j.brainres.2011.01.057
    • Bee LA, Bannister K, Rahman W, Dickenson AH (2011). Mu-opioid and noradrenergic α(2)-adrenoceptor contributions to the effects of tapentadol on spinal electrophysiological measures of nociception in nerve-injured rats.. Pain, 152(1), 131 - 139. doi:10.1016/j.pain.2010.10.004
    • Bannister K, Sikandar S, Bauer CS, Dolphin AC, Porreca F, Dickenson AH (2011). Pregabalin suppresses spinal neuronal hyperexcitability and visceral hypersensitivity in the absence of peripheral pathophysiology.. Anesthesiology, 115(1), 144 - 152. doi:10.1097/ALN.0b013e31821f6545

    2010

    • Kaan TK, Yip PK, Patel S, Davies M, Marchand F, Cockayne DA, Nunn PA, Dickenson AH, Ford AP, Zhong Y, Malcangio M, McMahon SB (2010). Systemic blockade of P2X3 and P2X2/3 receptors attenuates bone cancer pain behaviour in rats.. Brain, 133(9), 2549 - 2564. doi:10.1093/brain/awq194
    • Asante CO, Dickenson AH (2010). Descending serotonergic facilitation mediated by spinal 5-HT3 receptors engages spinal rapamycin-sensitive pathways in the rat.. Neurosci Lett, 484(2), 108 - 112. doi:10.1016/j.neulet.2010.08.024
    • Neziri AY, Andersen OK, Petersen-Felix S, Radanov B, Dickenson AH, Scaramozzino P, Arendt-Nielsen L, Curatolo M (2010). The nociceptive withdrawal reflex: Normative values of thresholds and reflex receptive fields. EUR J PAIN, 14(2), - . doi:10.1016/j.ejpain.2009.04.010
    • Bauer CS, Rahman W, Tran-van-Minh A, Lujan R, Dickenson AH, Dolphin AC (2010). The anti-allodynic alpha(2)delta ligand pregabalin inhibits the trafficking of the calcium channel alpha(2)delta-1 subunit to presynaptic terminals in vivo.. Biochem Soc Trans, 38(2), 525 - 528. doi:10.1042/BST0380525
    • Bannister K, Dickenson AH (2010). Opioid hyperalgesia.. Curr Opin Support Palliat Care, 4(1), 1 - 5. doi:10.1097/SPC.0b013e328335ddfe
    • Asante CO, Wallace VC, Dickenson AH (2010). Mammalian target of rapamycin signaling in the spinal cord is required for neuronal plasticity and behavioral hypersensitivity associated with neuropathy in the rat.. J Pain, 11(12), 1356 - 1367. doi:10.1016/j.jpain.2010.03.013

    2009

    • Bee LA, Dickenson AH (2009). The importance of the descending monoamine system for the pain experience and its treatment.. F1000 Med Rep, 1, - . doi:10.3410/M1-83
    • Neziri AY, Andersen OK, Dickenson AH, Arendt-Nielsen L, Curatolo M (2009). Interaction of gender with age for pressure pain thresholds in pain-free humans. SWISS MED WKLY, 139(41-42), 5S - 5S.
    • Bannister K, Bee LA, Dickenson AH (2009). Preclinical and early clinical investigations related to monoaminergic pain modulation.. Neurotherapeutics, 6(4), 703 - 712. doi:10.1016/j.nurt.2009.07.009
    • Vonsy JL, Ghandehari J, Dickenson AH (2009). Differential analgesic effects of morphine and gabapentin on behavioural measures of pain and disability in a model of osteoarthritis pain in rats.. Eur J Pain, 13(8), 786 - 793. doi:10.1016/j.ejpain.2008.09.008
    • Bee LA, Dickenson AH (2009). Effects of lacosamide, a novel sodium channel modulator, on dorsal horn neuronal responses in a rat model of neuropathy.. Neuropharmacology, 57(4), 472 - 479. doi:10.1016/j.neuropharm.2009.06.021
    • Bauer CS, Nieto-Rostro M, Rahman W, Tran-Van-Minh A, Ferron L, Douglas L, Kadurin I, Sri Ranjan Y, Fernandez-Alacid L, Millar NS, Dickenson AH, Lujan R, Dolphin AC (2009). The increased trafficking of the calcium channel subunit alpha2delta-1 to presynaptic terminals in neuropathic pain is inhibited by the alpha2delta ligand pregabalin.. J Neurosci, 29(13), 4076 - 4088. doi:10.1523/JNEUROSCI.0356-09.2009
    • Harvey VL, Caley A, Müller UC, Harvey RJ, Dickenson AH (2009). A Selective Role for alpha3 Subunit Glycine Receptors in Inflammatory Pain.. Front Mol Neurosci, 2, 14 - . doi:10.3389/neuro.02.014.2009
    • Nguyen D, Deng P, Matthews EA, Kim DS, Feng GP, Dickenson AH, Xu ZC, Luo ZD (2009). Enhanced pre-synaptic glutamate release in deep-dorsal horn contributes to calcium channel alpha-2-delta-1 protein-mediated spinal sensitization and behavioral hypersensitivity. MOL PAIN, 5, - . doi:10.1186/1744-8069-5-6
    • Bauer C, Nieto-Rostro M, Rahman W, Tran-Van-Minh A, Ferron L, Douglas L, Kadurin I, Sri Ranjan Y, Fernandez-Alacid L, Millar NS, Dickenson AH, Lujan R, Dolphin AC (2009). The increased trafficking of the calcium channel subunit α2δ-1 to presynaptic terminals in neuropathic pain is inhibited by the α2δ ligand pregabalin.. Journal of Neuroscience, 29, 4076 - 4088.
    • Rahman W, Bauer CS, Bannister K, Vonsy J-L, Dolphin AC, Dickenson AH (2009). Descending serotonergic facilitation and the antinociceptive effects of pregabalin in a rat model of osteoarthritic pain.. Molecular Pain, 5, 45 - .
    • Harvey VL, Dickenson AH (2009). Behavioural and electrophysiological characterisation of experimentally induced osteoarthritis and neuropathy in C57Bl/6 mice.. Mol Pain, 5, 18 - . doi:10.1186/1744-8069-5-18
    • Asante CO, Wallace VC, Dickenson AH (2009). Formalin-induced behavioural hypersensitivity and neuronal hyperexcitability are mediated by rapid protein synthesis at the spinal level.. Mol Pain, 5, 27 - . doi:10.1186/1744-8069-5-27
    • Maratou K, Wallace VCJ, Hasnie FS, Okuse K, Hosseini R, Jina N, Blackbeard J, Pheby T, Orengo C, Dickenson AH, McMahon SB, Rice ASC (2009). Comparison of dorsal root ganglion gene expression in rat models of traumatic and HIV-associated neuropathic pain. EUR J PAIN, 13(4), 387 - 398. doi:10.1016/j.ejpain.2008.05.011

    2008

    • Bee LA, Dickenson AH (2008). Descending facilitation from the brainstem determines behavioural and neuronal hypersensitivity following nerve injury and efficacy of pregabalin.. Pain, 140(1), 209 - 223. doi:10.1016/j.pain.2008.08.008
    • D'Mello R, Dickenson AH (2008). Spinal cord mechanisms of pain.. Br J Anaesth, 101(1), 8 - 16. doi:10.1093/bja/aen088
    • Rahman W, Suzuki R, Hunt SP, Dickenson AH (2008). Selective ablation of dorsal horn NK1 expressing cells reveals a modulation of spinal alpha2-adrenergic inhibition of dorsal horn neurones. Neuropharmacology, 54(8), 1208 - 1214. doi:10.1016/j.neuropharm.2008.03.014
    • Harvey VL, Dickenson AH (2008). Mechanisms of pain in nonmalignant disease.. Curr Opin Support Palliat Care, 2(2), 133 - 139. doi:10.1097/SPC.0b013e328300eb24
    • Abrahamsen B, Zhao J, Asante CO, Cendan CM, Marsh S, Martinez-Barbera JP, Nassar MA, Dickenson AH, Wood JN (2008). The cell and molecular basis of mechanical, cold, and inflammatory pain. Science, 321(5889), 702 - 705.
    • Perrot S, Dickenson AH, Bennett RM (2008). Fibromyalgia: harmonizing science with clinical practice considerations.. Pain Pract, 8(3), 177 - 189. doi:10.1111/j.1533-2500.2008.00190.x
    • Pezet S, Marchand F, D'Mello R, Grist J, Clark AK, Malcangio M, Dickenson AH, Williams RJ, McMahon SB (2008). Phosphatidylinositol 3-kinase is a key mediator of central sensitization in painful inflammatory conditions. J NEUROSCI, 28(16), 4261 - 4270. doi:10.1523/JNEUROSCI.5392-07.2008
    • Rahman W, D'Mello R, Dickenson AH (2008). Peripheral Nerve Injury-Induced Changes in Spinal alpha(2)-Adrenoceptor-Mediated Modulation of Mechanically Evoked Dorsal Horn Neuronal Responses.. The Journal of Pain, 9(4), 350 - 359.
    • Rahman W, Sikandar S, Suzuki R, Hunt SP, Dickenson AH (2008). Superficial NK1 expressing spinal dorsal horn neurones modulate inhibitory neurotransmission mediated by spinal GABA(A) receptors (vol 419, pg 278, 2007). NEUROSCI LETT, 434(3), 315 - 315. doi:10.1016/j.neulet.2008.02.001
    • Urch CE, Dickenson AH (2008). Neuropathic pain in cancer.. Eur J Cancer, 44(8), 1091 - 1096. doi:10.1016/j.ejca.2008.03.015

    2007

    • Woolf CJ, Dickenson AH, Taylor CP, Tolle TR (2007). alpha(2)-delta and chronic disorders - A journey of exploration.
    • Bee LA, Dickenson AH (2007). Rostral ventromedial medulla control of spinal sensory processing in normal and pathophysiological states.. Neuroscience, 147(3), 786 - 793.
    • Altier C, Dale CS, Kisilevsky AE, Chapman K, Castiglioni AJ, Matthews EA, Evans RM, Dickenson AH, Lipscombe D, Vergnolle N, Zamponi GW (2007). Differential role of N-type calcium channel splice isoforms in pain.. Journal of Neuroscience, 27(24), 6363 - 6373.
    • Rahman W, Sikander S, Suzuki R, Hunt SP, Dickenson AH (2007). Superficial NK1 expressing spinal dorsal horn neurones modulate inhibitory neurotransmission mediated by spinal GABAA receptors. Neuroscience Letters, 419(3), 278 - 283. doi:10.1016/j.neulet.2007.04.039
    • Dickenson AH, Ghandehari J (2007). Anti-convulsants and anti-depressants.. Handb Exp Pharmacol, (177), 145 - 177.
    • Rojas-Piloni G, Dickenson AH, Condà s-Lara M (2007). Superficial dorsal horn neurons with double spike activity in the rat.. Neuroscience Letters, 419(2), 147 - 152.
    • Gordon-Williams RM, Dickenson AH (2007). Central neuronal mechanisms in cancer-induced bone pain.. Curr Opin Support Palliat Care, 1(1), 6 - 10. doi:10.1097/SPC.0b013e328133f5e9
    • Hasnie FS, Breuer J, Parker S, Wallace V, Blackbeard J, Lever I, Kinchington PR, Dickenson AH, Pheby T, Rice AS (2007). Further characterization of a rat model of varicella zoster virus-associated pain: Relationship between mechanical hypersensitivity and anxiety-related behavior, and the influence of analgesic drugs.. Neuroscience, 144(4), 1495 - 1508.
    • Matthews EA, Bee LA, Stephens GJ, Dickenson AH (2007). The Cav2.3 calcium channel antagonist SNX-482 reduces dorsal horn neuronal responses in a rat model of chronic neuropathic pain.. European Journal of Neuroscience, 25(12), 3561 - 3569.

    2006

    • Li CY, Zhang XL, Matthews EA, Li KW, Kurwa A, Boroujerdi A, Gross J, Gold MS, Dickenson AH, Feng G, Luo ZD (2006). Calcium channel alpha2delta1 subunit mediates spinal hyperexcitability in pain modulation.. Pain, 125(1), 20 - 34.
    • Suzuki R, Porreca F, Dickenson AH (2006). Evidence for spinal dorsal horn hyperexcitability in rats following sustained morphine exposure.. Neuroscience Letters, 407(2), 156 - 161.
    • Foulkes T, Nassar MA, Lane T, Matthews EA, Baker MD, Gerke V, Okuse K, Dickenson AH, Wood JN (2006). Deletion of annexin 2 light chain p11 in nociceptors causes deficits in somatosensory coding and pain behavior.. Journal of Neuroscience, 26(41), 10499 - 10507. doi:10.1523/JNEUROSCI.1997-06.2006
    • Rahman W, Suzuki R, Webber M, Hunt SP, Dickenson AH (2006). Depletion of endogenous spinal 5-HT attenuates the behavioural hypersensitivity to mechanical and cooling stimuli induced by spinal nerve ligation.. Pain, 123(3), 264 - 274.
    • Rygh LJ, Suzuki R, Rahman W, Wong Y, Vonsy JL, Sandhu H, Webber M, Hunt S, Dickenson AH (2006). Local and descending circuits regulate long-term potentiation and zif268 expression in spinal neurons. European Journal of Neuroscience, 24(3), 761 - 772.
    • Geranton S, Dickenson AH, Hunt SP (2006). New targets for the control of chronic pain: where should we look. ACTA PHARMACOL SIN, 27, 5 - 5.
    • Suzuki R, Dickenson AH (2006). Differential pharmacological modulation of the spontaneous stimulus-independent activity in the rat spinal cord following peripheral nerve injury.. Experimental Neurology, 198(1), 72 - 80.
    • Suzuki R, Dickenson AH (2006). Differential pharmacological modulation of the spontaneous stimulus-independent activity in the rat spinal cord following peripheral nerve injury. EXP NEUROL, 198(1), 72 - 80. doi:10.1016/j.expneruol.2005.10.032
    • Donovan-Rodriguez T, Urch CE, Dickenson AH (2006). Evidence of a role for descending serotonergic facilitation in a rat model of cancer-induced bone pain.. Neuroscience Letters, 393(2), 237 - 242.
    • Mathews E, Wood JN, Dickenson AH (2006). Nav 1.8-null mice show stimulus-dependent deficits in spinal neuronal activity. Molecular Pain, 14(2), 5 - .

    2005

    • Dickenson AH, Bee LA, Suzuki R (2005). Pains, gains, and midbrains.. Proceedings of the National Academy of Sciences of the United States of America, 102(50), 17885 - 17886.
    • Urch CE, Donovan-Rodriguez T, Gordon-Williams R, Bee LA, Dickenson AH (2005). Efficacy of chronic morphine in a rat model of cancer-induced bone pain: behavior and in dorsal horn pathophysiology.. The Journal of Pain, 6(12), 837 - 845.
    • Suzuki R, Rahman W, Rygh LJ, Webber M, Hunt SP, Dickenson AH (2005). Spinal-supraspinal serotonergic circuits regulating neuropathic pain and its treatment with gabapentin. Pain, 117, 292 - 303. doi:10.1016/j.pain.2005.06.015
    • Condes-Lara M, Maie IA, Dickenson AH (2005). Oxytocin actions on afferent evoked spinal cord neuronal activities in neuropathic but not in normal rats.. Brain Research, 1045(1), 124 - 133.
    • Stirling LC, Forlani G, Baker MD, Wood JN, Matthews EA, Dickenson AH, Nassar MA (2005). Nociceptor-specific gene deletion using heterozygous NaV1.8-Cre recombinase mice.. Pain, 113(1), 27 - 36.
    • Dickenson AH, Suzuki R (2005). Opioids in neuropathic pain: clues from animal studies.. European Journal of Pain, 9(2), 113 - 116.
    • Hansson PT, Dickenson AH (2005). Pharmacological treatment of peripheral neuropathic pain conditions based on shared commonalities despite multiple etiologies.. Pain, 113(3), 251 - 254.
    • Donovan-Rodriguez T, Dickenson AH, Urch CE (2005). Gabapentin normalizes spinal neuronal responses that correlate with behavior in a rat model of cancer-induced bone pain. Anesthesiology, 102, 132 - 140.
    • Bahia PK, Suzuki R, Benton DCH, Jowett AJ, Chen M, Trezise DJ, Dickenson AH, Moss GWJ (2005). A Functional Role for Small-Conductance Calcium-Activated Potassium Channels in Sensory Pathways Including Nociceptive Processes.. Journal of Neuroscience, 25, 3489 - 3498. doi:10.1523/JNEUROSCI.0597-05.2005

    2004

    • Donovan-Rodriguez T, Dickenson AH, Urch CE (2004). Gabapentin normalises the dorsal horn neuronal response in a rat model of cancer-induced bone pain. FUNDAMENTAL & CLINICAL PHARMACOLOGY, 18, 106 - 106.
    • Williams DG, Dickenson AH, Fitzgerald M, Howard RF (2004). Developmental regulation of codeine analgesia in the rat. Anesthesiology, 100, 92 - 97.
    • Nassar MA, Stirling LC, Forlani G, Baker MD, Matthews EA, Dickenson AH, Wood JN (2004). Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1) in acute and inflammatory pain. Proceedings of the National Academy of Sciences of the United States of America, (101), 12706 - 12711. doi:10.1073/pnas.0404915101
    • Suzuki R, Edwards M, Dickenson AH (2004). ReN-1869 [(R)-1-(3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-propyl)-3-piperidine carboxylic acid], a novel histamine H1 receptor antagonist, produces potent and selective antinociceptive effects on dorsal horn neurons after inflammation and neuropathy.. J Pharmacol Exp Ther, 309(3), 1230 - 1238. doi:10.1124/jpet.103.063511
    • Suzuki R, Rahman W, Hunt SP, Dickenson AH (2004). Descending facilitatory control of mechanically evoked responses is enhanced in deep dorsal horn neurones following peripheral nerve injury. Brain Research, 1019(1-2), 68 - 76.
    • Rahman W, Suzuki R, Rygh LJ, Dickenson AH (2004). Descending serotonergic facilitation mediated through spinal 5HT3 receptors is unaltered following carrageenan inflammation. Neuroscience Letters, 361, 229 - 231.
    • Maie IA, Dickenson AH (2004). Cholecystokinin fails to block the spinal inhibitory effects of nociceptin of sham operated and neuropathic rats. European Journal of Pharmacology, 484, 235 - 240.
    • Suzuki R, Edwards M, Dickenson AH (2004). ReN-1869 [(R)-1-(3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-propyl)-3-piperidine carboxylic acid], a novel histamine H1 receptor antagonist, produces potent and selective antinociceptive effects on dorsal horn neurons after inflammation and. Journal of Experimental Therapeutics, 309, 1230 - 1238.
    • Williams G, Fitzgerald M, Dickenson AH, Howard R (2004). Developmental regulation of codeine analgesia. Anesthesiology, 100, 92 - 97.
    • Seagrove LC, Suzuki R, Dickenson AH (2004). Electrophysiological characterisations of rat lamina I dorsal horn neurones and the involvement of excitatory amino acid receptors. Pain, 108, 76 - 87.
    • Matthews EA, Dickenson AH (2004). Effects of spinally administered adenine on dorsal horn neuronal responses in a rat model of inflammation. Neuroscience Letters, (356), 211 - 214.
    • Donovan-Rodriguez T, Dickenson AH, Urch CE (2004). Superficial dorsal horn neuronal responses and the emergence of behavioural hyperalgesia in a rat model of cancer-induced bone pain. Neuroscience Letters, (360), 29 - 32.
    • Flatters SJL, Fox A, Dickenson AH (2004). Nerve injury alters the effects of interleukin-6 on nociceptive transmission in peripheral afferents. European Journal of Pharmacology, (484), 183 - 191.
    • Stanfa LC, Dickenson AH (2004). In vivo electrophysiology of dorsal-horn neurons. Methods in Molecular Medicine, (99), 139 - 153.
    • Chaddock JA, Purkiss JR, Alexander FC, Doward S, Fooks SJ, Friis LM, Hall YH, Kirby ER, Leeds N, Moulsdale HJ, Dickenson A, Green GM, Rahman W, Suzuki R, Duggan MJ, Quinn CP, Shone CC, Foster KA (2004). Retargeted clostridial endopeptidases: inhibition of nociceptive neurotransmitter release in vitro, and antinociceptive activity in in vivo models of pain. Movement Disorders, 19(Suppl), S42 - S47.
    • Suzuki R, Rygh LJ, Dickenson AH (2004). Bad news from the brain: descending 5-HT pathways that control spinal pain processing. Trends in Pharmacological Sciences, (25), 613 - 617.
    • (2004). The Pain System in Normal and Pathological States: A Primer for Clinicians Progress in Pain Research and Management.
    • Suzuki R, Rahman W, Hunt SP, Dickenson AH (2004). Descending facilitatory control of mechanically evoked responses is enhanced in deep dorsal horn neurones following peripheral nerve injury. BRAIN RES, 1019(1-2), 68 - 76. doi:10.1016/j.brianres.2004.05.108

    2003

    • Suzuki R, Hunt SP, Dickenson AH (2003). The coding of noxious mechanical and thermal stimuli of deep dorsal horn neurones is attenuated in NK1 knockout mice. Neuropharmacology, 45(8), 1093 - 1100. doi:10.1016/S0028-3908(03)00281-8
    • McCleane GJ, Suzuki R, Dickenson AH (2003). Does a single intravenous injection of the 5HT3 receptor antagonist ondansetron have an analgesic effect in neuropathic pain? A double-blinded, placebo-controlled cross-over study. ANESTH ANALG, 97(5), 1474 - 1478. doi:10.1213/01.ANE.0000085640.69855.51
    • Carpenter KJ, Sen S, Matthews EA, Flatters SL, Wozniak KM, Slusher BS, Dickenson AH (2003). Effects of GCP-II inhibition on responses of dorsal horn neurones after inflammation and neuropathy: an electrophysiological study in the rat.. Neuropeptides, 37(5), 298 - 306.
    • Flatters SJ, Fox AJ, Dickenson AH (2003). Spinal interleukin-6 (IL-6) inhibits nociceptive transmission following neuropathy.. Brain Res, 984(1-2), 54 - 62.
    • Suzuki R, Morcuende S, Webber M, Hunt SP, Dickenson AH (2003). What the brain tells the spinal cord: Lamina I/III NK1-expressing neurons control spinal activity via descending pathways.
    • Urch CE, Donovan-Rodriguez T, Dickenson AH (2003). Alterations in dorsal horn neurones in a rat model of cancer-induced bone pain. Pain, 106(3), 347 - 356.
    • Urch CE, Dickenson AH (2003). Neuronal nitric oxide synthase modulation of dorsal horn neuronal response in the rat: a developmental study. Developmental Neuroscience, 25(5), 301 - 307.
    • Urch CE, Dickenson AH (2003). In vivo single unit extracellular recordings from spinal cord neurones of rats. Brain Research Protocols, 12(1), 26 - 24.
    • Flatters SJ, Fox AJ, Dickenson AH (2003). In vivo and in vitro effects of peripheral galanin on nociceptive transmission in naive and neuropathic states. Neuroscience, 116(4), 1005 - 1012.
    • Passmore GM, Selyanko AA, Mistry M, Al Qatari M, Marsh SJ, Matthews EA, Dickenson AH, Brown TA, Burbidge SA, Main M, Brown DA (2003). KCNQ/M currents in sensory neurons: significance for pain therapy. Journal of Neuroscience, 23(18), 7227 - 7236.

    2002

    • Suzuki R, Morcuende S, Webber M, Hunt SP, Dickenson AH (2002). Superficial NK1-expressing neurons control spinal excitability through activation of descending pathways. Nature Neuroscience, 5(12), 1319 - 1326. doi:10.1038/nn966
    • Carpenter KJ, Dickenson AH (2002). Molecular aspects of pain research.. Pharmacogenomics J, 2(2), 87 - 95.
    • Dickenson AH (2002). Recent advances in the mechanisms of pain. BRIT J PHARMACOL, 136, - .
    • Chaddock JA, Duggan MJ, Hall YHJ, Kirby ER, Moulsdale HJ, Purkiss JR, Quinn CP, Shone CC, Dickenson AH, Cui M, Aoki KR, Foster KA (2002). Retargeted clostridial endopeptidases: Inhibition of nociceptive neurotransmitter release in vitro, and antinociceptive activity in in vivo models of pain. N-S ARCH PHARMACOL, 365, R15 - R15.
    • Carpenter KC, Dickenson AH (2002). Molecular aspects of pain. Pharmacogenetics Journal, 2, 87 - 95.
    • Dickenson AH, Matthews EA, Suzuki R (2002). Neurobiology of neuropathic pain: mode of action of anticonvulsants. European Journal of Pain, 6(0), 51 - 60.
    • Dickenson AH (2002). Gate Control Theory of pain stands the test of time. British Journal of Anaesthesia, 88(6), 755 - 757.
    • Duggan MJ, Quinn CP, Chaddock JA, Purkiss JR, Alexander FCG, Doward S, Fooks SJ, Friis LM, Hall YHJ, Kirby ER, Leeks N, Moulsdale HJ, Dickenson AH, Green GM, Rahman W, Suzuki R, Shone CC, Foster KA (2002). Inhibition of release of neurotransmitters from rat dorsal root ganglia by a novel conjugate of a Clostridium botulinum toxin A endopeptidase fragment and Erythrina cristagalli lectin. Journal of Biological Chemistry, 277, 34846 - 34852.
    • Flatters SJL, Fox AJ, Dickenson AH (2002). Nerve injury induces plasticity that results in spinal inhibitory effects of galanin. Pain, 98, 249 - 258.
    • Matthews EA, Dickenson AH (2002). A combination of gabapentin and morphine mediates enhanced inhibitory effects on dorsal horn neuronal responses in a rat model of neuropathy. Anesthesiology, 96(3), 633 - 640.
    • Suzuki R, Dickenson AH (2002). Nerve injury-induced changes in opioid modulation of wide dynamic range dorsal column nuclei neurones. Neuroscience, 111(1), 215 - 228.
    • Suzuki R, Green GM, Millan MJ, Dickenson AH (2002). Electrophysiologic characterization of the antinociceptive actions of S18616, a novel and potent alpha2-adrenoceptor agonist, after acute and persistent pain states. The Journal of Pain, 3(3), 234 - 243.
    • Suzuki R, Dickenson AH (2002). Neuropharmacological targets and agents in fibromyalgia. Pain and Headache Reviews, 6, 267 - 273.
    • Suzuki R, Dickenson AH (2002). The pharmacology of central sensitization. Journal of Musculoskeletal Pain, 10, 35 - 43.
    • Flatters SJL, Fox AJ, Dickenson AH (2002). Nerve injury induces plasticity that results in spinal inhibitory effects of galanin (vol 98, pg 249, 2002). PAIN, 99(3), 611 - 613.

    2001

    • Suzuki R, Stanfa L, Kowaluk E, Williams M, Jarvis M, Dickenson AH (2001). The effect of ABT-702, a novel adenosine kinase inhibitor, on the responses of spinal neurons following carrageenan inflammation and peripheral nerve injury. British Journal of Pharmacology, 132, 1615 - 1623.
    • Matthews EM, Dickenson AH (2001). Effects of ethosuximide, a T-type calcium channel blocker, on dorsal horn neuronal responses in rats. European Journal of Pharmacology, 415, 141 - 149.
    • Urch CE, Rahman W, Dickenson AH (2001). Electrophysiological studies on the role of the NMDA receptor in nociception in the developing rat spinal cord. Developmental Brain Research, 126, 81 - 89.
    • Dickenson AH (2001). A lot of gain but not much pain. TRENDS PHARMACOL SCI, 22(4), 208 - 209.
    • Kontinen VK, Stanfa LC, Basu A, Dickenson AH (2001). Electrophysiologic evidence for increased endogenous gabaergic but not glycinergic inhibitory tone in the rat spinal nerve ligation model of neuropathy.. Anesthesiology, 94(2), 333 - 339.
    • Carpenter KJ, Nandi M, Dickenson AH (2001). Peripheral administration of low pH solutions causes activation and sensitisation of convergent dorsal horn neurons in the anaesthetized rat. Neuroscience Letters, 298, 179 - 182.
    • Carpenter KJ, Dickenson AH (2001). Amino acids are still as exciting as ever. Current Opinion in Pharmacology, 1, 57 - 61.
    • Dickenson AH, Matthews EA, Suzuki R (2001). Function and Dysfunction of Opioid Receptors in the Spinal Cord. In Hanson PT, Fields HL, Hill RG, Marchettini P (Ed.), Neuropathic Pain Pathophysiology and Treatment, Progress in Pain Research and Management (pp. 185 - 206). : IASP Press.
    • Dickenson AH (2001). Opiates. In Elsevier (Ed.), Encyclopaedia of Life Sciences (web only) (pp. - ). : .
    • Dickenson AH (2001). Pain and Analgesia. In Webster RA (Ed.), Neurotransmitters, Drugs and Brain Function (pp. 453 - 476). : Wiley.
    • Dickenson AH (2001). Drug Dependence and Abuse. In Webster RA (Ed.), Neurotransmitters, Drugs and Brain Function (pp. 499 - 520). : Wiley.
    • Dickenson AH (2001). Amino Acids: excitatory. In Webster RA (Ed.), Neurotransmitters, Drugs and Brain Function (pp. 211 - 224). : Wiley.
    • Dickenson AH (2001). Peptides. In Webster RA (Ed.), Neurotransmitters, Drugs and Brain Function (pp. 251 - 264). : Wiley.
    • Hodgson DM, Maxwell CR, Wisedale R, Matthews IR, Carpenter KJ, Dickenson AH, Wonnacott S (2001). 6-substituted 2-azabicyclo[2.2.1]hept-5-enes by nitrogen-directed radical rearrangement: synthesis of an epibatidine analogue with high binding affinity at the nicotinic acetylcholine receptor. Journal of the Chemical Society, Perkin Transactions 1, 2001(23), 3150 - 3158. doi:10.1039/b107414h
    • Kontinen VC, Stanfa L, Suzuki R, Dickenson AH (2001). Electrophysiological evidence for increased endogenous GABAergic but not glycinergic inhibitory tone in the rat spinal nerve ligation model of neuropathy. Anesthesiology, 94, 313 - 329.
    • Matthews EM, Dickenson AH (2001). Effects of spinally delivered N- and P-type voltage-dependent calcium channel antagonists on dorsal horn neuronal responses in a rat model of neuropathy. Pain, 92, 235 - 246.
    • Suzuki R, Matthews EM, Dickenson AH (2001). Comparison of the effects of MK-801, ketamine and memantine on responses of spinal dorsal horn neurons in a rat model of mononeuropathy. Pain, 91, 101 - 109.

    2000

    • Suzuki R, Kontinen VK, Matthews E, Williams E, Dickenson AH (2000). Enlargement of the receptive field size to low intensity mechanical stimulation in the rat spinal nerve ligation model of neuropathy.. Exp Neurol, 163(2), 408 - 413. doi:10.1006/exnr.2000.7371
    • Suzuki R, Gale A, Dickenson AH (2000). Altered effects of an A(1) adenosine receptor agonist on the evoked responses of spinal dorsal horn neurones in a rat model of mononeuropathy. J PAIN, 1(2), 99 - 110. doi:10.1054/xb.2000.6055
    • Suzuki R, Kontinen V, Matthews E, Williams E, Dickenson AH (2000). Enlargement of the receptive field size to low intensity mechanical stimulation in the spinal nerve ligation model of neuropathy in rats. Experimental Neurology, 163, 408 - 413.
    • Green GM, Scarth J, Dickenson AH (2000). An excitatory role for 5-HT in spinal inflammatory nociceptive transmission; state-dependent actions via dorsal horn 5-HT3 receptors in the anaesthetised rat. Pain, 89, 81 - 88.
    • Carpenter K, Chapman V, Dickenson AH (2000). Neuronal inhibitory effects of methadone are predominantly opioid receptor mediated in the rat spinal cord in vivo. European Journal of Pain, 4, 19 - 26.
    • Carpenter K, Vithlani M, Dickenson AH (2000). Unaltered peripheral excitatory actions of nociceptin contrast with enhanced spinal inhibitory effects after carrageenan inflammation: an electrophysiological study in the rat. Pain, 85, 433 - 441.
    • Dickenson AH, Suzuki R, Reeve A (2000). Adenosine as a potential analgesic target in inflammatory and neuropathic pains. CNS Drugs, 13, 77 - 85.
    • Kontinen V, Dickenson AH (2000). Effects of midazolam in the spinal nerve ligation model of neuropathic pain in rats. Pain, 85, 425 - 431.
    • Rygh LJ, Green M, Athauda N, Tjolsen A, Dickenson AH (2000). The effect of spinal morphine following long-term potentiation of wide dynamic range neurones in the rat. Anesthesiology, 92, 140 - 146.
    • Rygh LJ, Kontinen V, Suzuki R, Dickenson AH (2000). Different increase in C-fibre evoked responses after nociceptive conditioning stimulation in sham-operated and neuropathic rats. Neuroscience Letters, 288, 99 - 103.
    • Souslova V, Cesare P, Ding Y, Akopian AN, Stanfa L, Suzuki R, Carpenter K, Dickenson AH, Boyce S, Hill R, Nebenius-Oosthuizen D, Smith AH, Kidd EJ, Wood JN (2000). Warm coding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors. Nature, 407, 1015 - 1017.
    • Stanfa LC, Kontinen V, Dickenson AH (2000). Effect of spinally administered P2X receptor agonists and antagonists on the responses of dorsal horn neurones recorded in normal, carrageenan-inflamed and neuropathic rats. British Journal of Pharmacology, 129, 351 - 359.
    • Stanfa LC, Hampton DW, Dickenson AH (2000). Role of Ca2+ permeable non-NMDA glutmate receptors in spinal nociceptive transmission. NeuroReport, 11, 3199 - 3202.
    • Suzuki R, Dickenson AH (2000). Neuropathic pain: Nerves bursting with excitement. NeuroReport, 11, - .
    • Suzuki R, Gale A, Dickenson AH (2000). The inhibitory effects of the A1 adenosine receptor agonist, N6-cyclopentyladenosine on the electrical and natural evoked responses of spinal dorsal horn neurons in a rat model of mononeuropathy. The Journal of Pain, 1, 99 - 110.
    • Dickenson AH, Chapman V (2000). New and old anticonvulsants as analgesics.
    • Dickenson AH, Stanfa LC, Kontinen V, Suzuki R, Carpenter K (2000). Comment on: Svendsen et al., Some problems with wind-up and its calculation, PAIN 83 (1999) 109-111. PAIN, 85(3), 524 - 524.

    1999

    • Dickenson AH, Carpenter K, Suzuki R (1999). Pain relief.. IDrugs, 2(11), 1130 - 1132.
    • Carpenter KJ, Dickenson AH (1999). NMDA receptors and pain - Hopes for novel analgesics. REGION ANESTH PAIN M, 24(6), 506 - 508.
    • Chizh BA, Dickenson AH, Wnendt S (1999). The race to control pain: more participants, more targets.. Trends Pharmacol Sci, 20(9), 354 - 357.
    • Marsh D, Dickenson A, Hatch D, Fitzgerald M (1999). Epidural opioid analgesia in infant rats I: mechanical and heat responses. Pain, 82(1), 23 - 32.
    • Marsh D, Dickenson A, Hatch D, Fitzgerald M (1999). Epidural opioid analgesia in infant rats II: responses to carrageenan and capsaicin. Pain, 82(1), 33 - 38.
    • Akopian AN, Souslova V, England S, Okuse K, Ogata N, Ure J, Smith A, Kerr BJ, McMahon SB, Boyce S, Hill R, Stanfa LC, Dickenson AH, Wood JN (1999). The tetrodotoxin-resistant sodium channel SNS has a specialized function in pain pathways. Nature Neuroscience, , 541 - 548.
    • Chizh BA, Dickenson AH, Whendt S (1999). The race to pain control: more participants, more targets. Trends in Pharmacological Sciences, 20, 354 - 357.
    • Dickenson AH, Reeve A (1999). Neurophysiology of Acute and Chronic Pain. In Sawynok J, Cowan A (Ed.), Novel Aspects of Pain Management: Opioids and Beyond (pp. 1 - 20). : Wiley-Liss.
    • Dickenson AH, Rahman W (1999). Mechanisms of Chronic Pain and the Developing Nervous System. In McGrath PJ, Finley GA (Ed.), Chronic and Recurrent Pain in Children and Adolescents, Progress in Pain Research and Management (pp. 1 - 34). : IASP Press.
    • Dickenson AH, Suzuki R (1999). Function and Dysfunction of Opioid Receptors in the Spinal Cord. In Kalso E, McQuay HJ, Wiesenfeld-Hallen Z (Ed.), Opioid Sensitivity of Chronic Noncancer Pain, Progress in Pain Research and Management (pp. 1 - 28). : IASP Press.
    • Dickenson AH, McQuay H (1999). 25 years of advances in pain research. IASP Newsletter, , - .
    • Dickenson AH, Carpenter K, Suzuki R (1999). International Association for the Study of Pain - meeting news. Investigational Drugs, 37, 27 - 30.
    • Rahman W, Dickenson AH (1999). Electrophysiological studies on the postnatal development of spinal antinociceptive effects of the delta opioid receptor agonist DPDPE in the rat. British Journal of Pharmacology, 126, 1115 - 1122.
    • Rahman W, Dickenson AH (1999). Development of spinal opioid systems. Journal of Regional Anaesthesia, 24, 383 - 385.
    • Stanfa LC, Dickenson AH (1999). The role of non-NMDA inonotropic receptors in the spinal transmission of nociception in normal animals and after carrageenan inflammation. Neuroscience, 93, 1391 - 1398.
    • Suzuki R, Chapman V, Dickenson AH (1999). The effectiveness of spinal and systemic morphine on rat dorsal horn neuronal responses in the spinal nerve ligation model of neuropathic pain. Pain, 80, 215 - 228.
    • Stanfa LC, Dickenson AH (1999). The role of non-N-methyl-D-aspartate ionotropic glutamate receptors in the spinal transmission of nociception in normal animals and animals with carrageenan inflammation.. Neuroscience, 93(4), 1391 - 1398.
    • Dickenson AH, Rahman W (1999). Mechanisms of chronic pain and the developing nervous system.
    • Dickenson AH, Suzuki R (1999). Function and dysfunction of opioid receptors in the spinal cord.

    1998

    • Bannon AW, Decker MW, Holladay MW, Curzon P, Donnelly-Roberts D, Puttfarcken PS, Bitner RS, Diaz A, Dickenson AH, Porsolt RD, Williams M, Arneric SP (1998). Broad-spectrum, non-opioid analgesic activity by selective modulation of neuronal nicotinic acetylcholine receptors. Science, 279, 77 - 81.
    • Diaz A, Mayer S, Dickenson AH (1998). Role of imidazoline I-2 receptors in acute and persistent nociception at the level of the spinal cord.. N-S ARCH PHARMACOL, 358(1), R171 - R171.
    • Rahman W, Dashwood MR, Fitzgerald M, Aynsley-Green A, Dickenson AH (1998). Postnatal development of multiple opioid receptors in the spinal cord and development of spinal morphine analgesia.. Brain Res Dev Brain Res, 108(1-2), 239 - 254.
    • Ebert B, Andersen S, Hjeds H, Dickenson AH (1998). Dextropropoxyphene acts as a noncompetitive N-methyl-D-aspartate antagonist. J PAIN SYMPTOM MANAG, 15(5), 269 - 274.
    • Reeve AJ, Dickenson AH, Kerr NC (1998). Spinal effects of bicuculline: modulation of an allodynia-like state by an A1-receptor agonist, morphine, and an NMDA-receptor antagonist.. J Neurophysiol, 79(3), 1494 - 1507.
    • Dickenson AH (1998). New pharmacological strategies in the treatment of pain. N-S ARCH PHARMACOL, 358(4), R770 - R770.
    • Green M, Lyons L, Dickenson AH (1998). à2 adrenoceptor antagonists enhance responses of dorsal horn neurones to formalin induced inflammation. European Journal of Pharmacology, 347, 201 - 204.
    • Rahman W, Dashwood MR, Fitzgerald M, Aynsley-Green A, Dickenson AH (1998). Postnatal development of multiple opioid receptors in the spinal cord and development of spinal morphine analgesia. Developmental Brain Research, 108, 239 - 254.
    • Carpenter KC, Dickenson AH (1998). Evidence that [Phe1y (CH2-NH) Gly2] nociceptin (1-13), a peripheral ORL-1 receptor antagonist, acts as an agonist in the rat spinal cord. British Journal of Pharmacology, 125, 949 - 951.
    • Chapman V, Suzuki R, Dickenson AH (1998). Electrophysiological characterisation of spinal neuronal response properties in anaesthetized rats after ligation of spinal nerves L5-L6. The Journal of Physiology, 507, 881 - 894.
    • Chapman V, Charmarette H, Suzuki R, Rygh L, Dickenson AH (1998). Effects of systemic carbamazepine and gabapentin on spinal neuronal responses in spinal nerve ligated rats. Pain, 75, 261 - 272.
    • Chapman V, Ng J, Dickenson AH (1998). A novel spinal site of action of mexiletine on somatosensory transmission in nerve-injured rats. Pain, 77, 289 - 296.
    • Ebert B, Andersen S, Hjeds H, Dickenson AH (1998). Dextropropoxyphene acts as non-competitive NMDA antagonist. Journal of Pain and Symptom Management, 15, 269 - 274.
    • Reeve AJ, Dickenson AH, Kerr NC (1998). Electrophysiology of an allodynia-like state: effects of NMDA antagonist, adenosine A1 receptor agonist and morphine. Journal of Neurophysiology, 79, 1494 - 1507.
    • Stanfa LC, Dickenson AH (1998). Inflammation alters the effects of mGlu receptor agonists on spinal nociceptive neurones. European Journal of Pharmacology, 347, 165 - 172.
    • Taylor F, Dickenson AH (1998). Nociceptin/orphanin FQ: new opioid new analgesic?. NeuroReport, , - .
    • Chapman V, Ng J, Dickenson AH (1998). A novel spinal action of mexiletine in spinal somatosensory transmission of nerve injured rats.. Pain, 77(3), 289 - 296.

    1997

    • Dickenson AH (1997). Pains, brains, and opium. BEHAV BRAIN SCI, 20(3), 479 - 482.
    • Dickenson AH (1997). NMDA receptor antagonists: interactions with opioids.. Acta Anaesthesiol Scand, 41(1 Pt 2), 112 - 115.
    • Chapman V, Wildman MA, Dickenson AH (1997). Distinct electrophysiological effects of two spinally administered membrane stabilising drugs, bupivacaine and lamotrigine.. Pain, 71(3), 285 - 295.
    • Chapman V, Dickenson AH (1997). Inflammation reveals inhibition of noxious responses of rat spinal neurones by carbamezapine. NeuroReport, 8, 1399 - 1404.
    • Chapman V, Wildman M, Dickenson AH (1997). Distinct electrophysiological effects of two spinally administered membrane stabilising drugs, bupivacaine and lamotrigine. Pain, 71, 275 - 285.
    • Chapman V, Diaz A, Dickenson AH (1997). Distinct inhibitory effects of spinal endomorphin-1 and endomorphin-1 on evoked dorsal horn neuronal responses in the rat. British Journal of Pharmacology, 122, 1537 - 1539.
    • Diaz A, Dickenson AH (1997). Blockade of spinal N- and P-type, but not L-type, calcium channels inhibits the excitability of rat dorsal horn neurones produced by subcutaneous formalin inflammation. Pain, 69, 93 - 100.
    • Diaz A, Mayet S, Dickenson AH (1997). BU-224 produces spinal antinociception as an agonist at imidazoline I2 receptors. European Journal of Pharmaceutical Sciences, 333, 9 - 15.
    • Dickenson AH, Besson JM (1997). The Pharmacology of Pain.
    • Dickenson AH, Chapman V, Green M (1997). The Pharmacology of excitatory and inhibitory amino-acid mediated events in the transmission and modulation of pain in the spinal cord. General Pharmacology, 28, 633 - 638.
    • Dickenson AH (1997). Plasticity: implication for opioid and other pharmacological interventions in specific pain states. Behavioral and Brain Sciences, 20(3), 392 - 403.
    • Dickenson AH (1997). NMDA - receptor antagonists: interactions with morphine. Acta Anaesthesiologica Scandinavica, 41, 112 - 115.
    • Dickenson AH (1997). GABA and persistent pain. Dolor, 12, 10 - 11.
    • Green M, Dickenson AH (1997). GABA receptor control of the amplitude and duration of the neuronal responses to formalin in the rat spinal cord. European Journal of Pain, 1, 95 - 104.
    • Stanfa LC, Singh L, Williams RG, Dickenson AH (1997). Gabapentin, ineffective in normal rats, markedly reduces C-fibre evoked responses after inflammation. NeuroReport, 8, 587 - 590.
    • Dickenson AH (1997). Nervous, excited and touchy: NMDA receptors in the spinal cord - A commentary. NEUROREPORT, 8(9-10), R1 - R1.

    1996

    • Stanfa LC, Misra C, Dickenson AH (1996). Amplification of spinal nociceptive transmission depends on the generation of nitric oxide in normal and carrageenan rats.. Brain Res, 737(1-2), 92 - 98.
    • Andersen S, Dickenson AH, Kohn M, Reeve A, Rahman W, Ebert B (1996). The opioid ketobemidone has a NMDA blocking effect. PAIN, 67(2-3), 369 - 374.
    • Boxall SJ, Thompson SW, Dray A, Dickenson AH, Urban L (1996). Metabotropic glutamate receptor activation contributes to nociceptive reflex activity in the rat spinal cord in vitro.. Neuroscience, 74(1), 13 - 20.
    • Dickenson AH (1996). Balances between excitatory and inhibitory events in the spinal cord and chronic pain.. Prog Brain Res, 110, 225 - 231.
    • Boxall SJ, Thompson SWN, Dray A, Dickenson AH, Urban L (1996). Metabotropic glutamate receptor activation contributes to the nociceptive reflex response in the neonatal rat spinal cord in vitro. BRIT J PHARMACOL, 117, P330 - P330.
    • Dickenson AH (1996). Opioid receptors: electrophysiological and neurophysiological approaches.. Acta Anaesthesiol Belg, 47(3), 101 - 104.
    • Stanfa LC, Chapman V, Kerr N, Dickenson AH (1996). Inhibitory action of nociceptin on spinal dorsal horn neurones of the rat, in vivo.. Br J Pharmacol, 118(8), 1875 - 1877.

    1995

    • Chapman V, Dickenson AH (1995). Time-related roles of excitatory amino acid receptors during persistent noxiously evoked responses of rat dorsal horn neurones.. Brain Res, 703(1-2), 45 - 50.
    • Reeve AJ, Dickenson AH (1995). The roles of spinal adenosine receptors in the control of acute and more persistent nociceptive responses of dorsal horn neurones in the anaesthetized rat.. Br J Pharmacol, 116(4), 2221 - 2228.
    • Dickenson AH (1995). Central acute pain mechanisms.. Ann Med, 27(2), 223 - 227.
    • Reeve AJ, Dickenson AH (1995). Electrophysiological study on spinal antinociceptive interactions between adenosine and morphine in the dorsal horn of the rat.. Neurosci Lett, 194(1-2), 81 - 84.
    • Dickenson AH (1995). Spinal cord pharmacology of pain.. Br J Anaesth, 75(2), 193 - 200.

    1994

    • Chapman V, Haley JE, Dickenson AH (1994). Electrophysiologic analysis of preemptive effects of spinal opioids on N-methyl-D-aspartate receptor-mediated events.. Anesthesiology, 81(6), 1429 - 1435.
    • Sullivan AF, Hewett K, Dickenson AH (1994). Differential modulation of alpha 2-adrenergic and opioid spinal antinociception by cholecystokinin and cholecystokinin antagonists in the rat dorsal horn: an electrophysiological study.. Brain Res, 662(1-2), 141 - 147.
    • Chapman V, Dickenson AH, Tjølsen A (1994). Bi-directional effects of intrathecal NMDA and substance P on rat dorsal horn neuronal responses.. Neurosci Lett, 178(1), 90 - 94.
    • Chapman V, Dickenson AH (1994). Enhanced responses of rat dorsal horn neurons after UV irradiation of the hindpaw; roles of the NMDA receptor.. Neurosci Lett, 176(1), 41 - 44.
    • Dickenson AH (1994). Neurophysiology of opioid poorly responsive pain.. Cancer Surv, 21, 5 - 16.
    • DICKENSON AH (1994). WHERE AND HOW DO OPIOIDS ACT.
    • STANFA LC, DICKENSON AH (1994). ENHANCED ALPHA-2-ADRENERGIC CONTROLS AND SPINAL MORPHINE POTENCY IN INFLAMMATION. NEUROREPORT, 5(4), 469 - 472.
    • Devillers JP, Mazarguil H, Allard M, Dickenson AH, Zajac JM, Simonnet G (1994). Characterization of a potent agonist for NPFF receptors: binding study on rat spinal cord membranes.. Neuropharmacology, 33(5), 661 - 669.
    • DICKENSON AH (1994). PRESYNAPTIC AND POSTSYNAPTIC EFFECTS OF OPIOIDS AT THE SPINAL LEVEL.
    • DEVILLERS JP, REEVE A, MAZARGUIL H, ALLARD M, ZAJAC JM, DICKENSON AH, SIMONNET G (1994). BIOCHEMICAL-CHARACTERIZATION OF A SYNTHETIC NPFF AGONIST WITH HIGH-AFFINITY AND RESISTANCE TO BRAIN PEPTIDASE INACTIVATION.
    • CHAPMAN V, DICKENSON AH (1994). SPINAL OPIATE SENSITIVITY IN MODELS OF INFLAMMATORY PAIN.
    • Stanfa LC, Dickenson AH (1994). Electrophysiological studies on the spinal roles of endogenous opioids in carrageenan inflammation.. Pain, 56(2), 185 - 191.
    • DICKENSON AH (1994). NMDA RECEPTOR ANTAGONISTS AS ANALGESICS.

    1993

    • Chapman V, Dickenson AH (1993). The effect of intrathecal administration of RP67580, a potent neurokinin 1 antagonist on nociceptive transmission in the rat spinal cord.. Neurosci Lett, 157(2), 149 - 152.
    • STANFA LC, DICKENSON AH (1993). CHANGES IN OPIOID SYSTEMS IN THE RAT SPINAL-CORD FOLLOWING PERIPHERAL CARRAGEENAN INFLAMMATION. BRIT J PHARMACOL, 109, P106 - P106.
    • Stanfa LC, Dickenson AH (1993). Cholecystokinin as a factor in the enhanced potency of spinal morphine following carrageenin inflammation.. Br J Pharmacol, 108(4), 967 - 973.
    • Hewett K, Dickenson AH, McQuay HJ (1993). Lack of effect of morphine-3-glucuronide on the spinal antinociceptive actions of morphine in the rat: an electrophysiological study.. Pain, 53(1), 59 - 63.
    • Kalso EA, Sullivan AF, McQuay HJ, Dickenson AH, Roques BP (1993). Cross-tolerance between mu opioid and alpha-2 adrenergic receptors, but not between mu and delta opioid receptors in the spinal cord of the rat.. J Pharmacol Exp Ther, 265(2), 551 - 558.

    1992

    • Chapman V, Dickenson AH (1992). The effects of sandostatin and somatostatin on nociceptive transmission in the dorsal horn of the rat spinal cord.. Neuropeptides, 23(3), 147 - 152.
    • Chapman V, Dickenson AH (1992). The spinal and peripheral roles of bradykinin and prostaglandins in nociceptive processing in the rat.. Eur J Pharmacol, 219(3), 427 - 433.
    • Stanfa LC, Sullivan AF, Dickenson AH (1992). Alterations in neuronal excitability and the potency of spinal mu, delta and kappa opioids after carrageenan-induced inflammation.. Pain, 50(3), 345 - 354.
    • Kalso EA, Sullivan AF, McQuay HJ, Dickenson AH (1992). Spinal antinociception by Tyr-D-Ser(otbu)-Gly-Phe-Leu-Thr, a selective delta-opioid receptor agonist.. Eur J Pharmacol, 216(1), 97 - 101.
    • Sullivan AF, Kalso EA, McQuay HJ, Dickenson AH (1992). Evidence for the involvement of the mu but not delta opioid receptor subtype in the synergistic interaction between opioid and alpha 2 adrenergic antinociception in the rat spinal cord.. Neurosci Lett, 139(1), 65 - 68.
    • STANFA LC, DICKENSON AH (1992). INCREASED POTENCY OF SPINAL OPIATES AFTER PERIPHERAL INFLAMMATION IN THE HALOTHANE ANESTHETIZED RAT. J PHYSIOL-LONDON, 446, P564 - P564.
    • Fraser HM, Chapman V, Dickenson AH (1992). Spinal local anaesthetic actions on afferent evoked responses and wind-up of nociceptive neurones in the rat spinal cord: combination with morphine produces marked potentiation of antinociception.. Pain, 49(1), 33 - 41.
    • Haley JE, Dickenson AH, Schachter M (1992). Electrophysiological evidence for a role of nitric oxide in prolonged chemical nociception in the rat.. Neuropharmacology, 31(3), 251 - 258.
    • Chapman V, Dickenson AH (1992). The combination of NMDA antagonism and morphine produces profound antinociception in the rat dorsal horn.. Brain Res, 573(2), 321 - 323.
    • Kalliomäki J, Schouenborg J, Dickenson AH (1992). Differential Effects of a Distant Noxious Stimulus on Hindlimb Nociceptive Withdrawal Reflexes in the Rat.. Eur J Neurosci, 4(7), 648 - 652.
    • DICKENSON AH, STANFA LC (1992). THE SEGMENTAL CONTROL OF PAIN.
    • Sullivan AF, Kalso EA, McQuay HJ, Dickenson AH (1992). The antinociceptive actions of dexmedetomidine on dorsal horn neuronal responses in the anaesthetized rat.. Eur J Pharmacol, 215(1), 127 - 133.

    1991

    • Dickenson AH (1991). Recent advances in the physiology and pharmacology of pain: plasticity and its implications for clinical analgesia.. J Psychopharmacol, 5(4), 342 - 351. doi:10.1177/026988119100500424
    • Dickenson AH, Sullivan AF, Stanfa LC, McQuay HJ (1991). Dextromethorphan and levorphanol on dorsal horn nociceptive neurones in the rat.. Neuropharmacology, 30(12A), 1303 - 1308.
    • Dickenson AH, Dray A (1991). Selective antagonism of capsaicin by capsazepine: evidence for a spinal receptor site in capsaicin-induced antinociception.. Br J Pharmacol, 104(4), 1045 - 1049.
    • Magnuson DS, Dickenson AH (1991). Lamina-specific effects of morphine and naloxone in dorsal horn of rat spinal cord in vitro.. J Neurophysiol, 66(6), 1941 - 1950.
    • Sullivan AF, Kalso EA, McQuay HJ, Dickenson AH (1991). FLFQPQRF-amide modulates alpha 2-adrenergic antinociception in the rat dorsal horn in vivo.. Brain Res, 562(2), 327 - 328.
    • KALSO E, SULLIVAN AF, MCQUAY HJ, DICKENSON AH (1991). INTERACTIONS BETWEEN ALPHA-2 ADRENERGIC, OPIOID AND FLFQPQRFAMIDE INFLUENCES ON NOCICEPTION IN THE DORSAL HORN OF ANESTHETIZED RAT. J PHYSIOL-LONDON, 438, P196 - P196.
    • Dickenson AH (1991). Mechanisms of the analgesic actions of opiates and opioids.. Br Med Bull, 47(3), 690 - 702.
    • Dickenson AH (1991). Capsaicin: gaps in our knowledge start to be filled.. Trends Neurosci, 14(7), 265 - 266.
    • Sullivan AF, Dickenson AH (1991). Electrophysiologic studies on the spinal antinociceptive action of kappa opioid agonists in the adult and 21-day-old rat.. J Pharmacol Exp Ther, 256(3), 1119 - 1125.
    • Dickenson AH, Aydar E (1991). Antagonism at the glycine site on the NMDA receptor reduces spinal nociception in the rat.. Neurosci Lett, 121(1-2), 263 - 266.
    • Dickenson AH, Sullivan AF (1991). NMDA receptors and central hyperalgesic states.. Pain, 46(3), 344 - 346.

    1990

    • Dickenson AH (1990). A cure for wind up: NMDA receptor antagonists as potential analgesics.. Trends Pharmacol Sci, 11(8), 307 - 309.
    • Dickenson AH, Sullivan AF, McQuay HJ (1990). Intrathecal etorphine, fentanyl and buprenorphine on spinal nociceptive neurones in the rat.. Pain, 42(2), 227 - 234.
    • Magnuson DS, Sullivan AF, Simonnet G, Roques BP, Dickenson AH (1990). Differential interactions of cholecystokinin and FLFQPQRF-NH2 with mu and delta opioid antinociception in the rat spinal cord.. Neuropeptides, 16(4), 213 - 218.
    • DICKENSON AH, MAGNUSON DSK, SULLIVAN AF (1990). THE ACTIONS OF MORPHINE AND NALOXONE ON SYNAPTICALLY AND L-GLUTAMATE ELICITED ACTIVITY OF RAT DORSAL HORN NEURONS INVITRO. J PHYSIOL-LONDON, 420, P44 - P44.
    • MCQUAY HJ, DICKENSON AH (1990). IMPLICATIONS OF NERVOUS-SYSTEM PLASTICITY FOR PAIN MANAGEMENT. ANAESTHESIA, 45(2), 101 - 102.
    • Dickenson AH, Sullivan AF (1990). Differential effects of excitatory amino acid antagonists on dorsal horn nociceptive neurones in the rat.. Brain Res, 506(1), 31 - 39.
    • DICKENSON AH, HALEY JE (1990). EVIDENCE FOR N-METHYL-D-ASPARTATE RECEPTOR INVOLVEMENT IN PROLONGED CHEMICAL NOCICEPTION IN THE ANESTHETIZED RAT. J PHYSIOL-LONDON, 420, P41 - P41.
    • Haley JE, Sullivan AF, Dickenson AH (1990). Evidence for spinal N-methyl-D-aspartate receptor involvement in prolonged chemical nociception in the rat.. Brain Res, 518(1-2), 218 - 226.

    1989

    • Sullivan AF, Dickenson AH, Roques BP (1989). Delta-opioid mediated inhibitions of acute and prolonged noxious-evoked responses in rat dorsal horn neurones.. Br J Pharmacol, 98(3), 1039 - 1049.
    • SMALLMAN K, DICKENSON AH, HALSEY MJ (1989). ELECTROPHYSIOLOGICAL STUDIES ON THE EFFECTS OF OPIATES ON DORSAL HORN NOCICEPTIVE NEURONS AT 51 ATMOSPHERES ABSOLUTE. PAIN, 38(1), 57 - 64.
    • Poree LR, Dickenson AH, Wei ET (1989). Corticotropin-releasing factor inhibits the response of trigeminal neurons to noxious heat.. Brain Res, 502(2), 349 - 355.
    • Haley JE, Dickenson AH, Schachter M (1989). Electrophysiological evidence for a role of bradykinin in chemical nociception in the rat.. Neurosci Lett, 97(1-2), 198 - 202.
    • McQuay HJ, Sullivan AF, Smallman K, Dickenson AH (1989). Intrathecal opioids, potency and lipophilicity.. Pain, 36(1), 111 - 115.
    • Sullivan AF, McQuay HJ, Bailey D, Dickenson AH (1989). The spinal antinociceptive actions of morphine metabolites morphine-6-glucuronide and normorphine in the rat.. Brain Res, 482(2), 219 - 224.

    1988

    • Dickenson AH, Sullivan AF, Roques BP (1988). Evidence that endogenous enkephalins and a delta opioid receptor agonist have a common site of action in spinal antinociception.. Eur J Pharmacol, 148(3), 437 - 439.
    • Sullivan AF, Dickenson AH (1988). Electrophysiological studies on the spinal effects of dermorphin, an endogenous mu-opioid agonist.. Brain Res, 461(1), 182 - 185.

    1987

    • Dickenson AH, Sullivan AF (1987). Peripheral origins and central modulation of subcutaneous formalin-induced activity of rat dorsal horn neurones.. Neurosci Lett, 83(1-2), 207 - 211.
    • Dickenson AH, Le Bars D (1987). Lack of evidence for increased descending inhibition on the dorsal horn of the rat following periaqueductal grey morphine microinjections.. Br J Pharmacol, 92(2), 271 - 280.
    • Dickenson AH, Sullivan AF (1987). Subcutaneous formalin-induced activity of dorsal horn neurones in the rat: differential response to an intrathecal opiate administered pre or post formalin.. Pain, 30(3), 349 - 360.
    • Dickenson AH, Sullivan AF (1987). Evidence for a role of the NMDA receptor in the frequency dependent potentiation of deep rat dorsal horn nociceptive neurones following C fibre stimulation.. Neuropharmacology, 26(8), 1235 - 1238.
    • Dickenson AH, Le Bars D (1987). Supraspinal morphine and descending inhibitions acting on the dorsal horn of the rat.. J Physiol, 384, 81 - 107.
    • SULLIVAN AF, DASHWOOD MR, DICKENSON AH (1987). ALPHA-2-ADRENOCEPTOR MODULATION OF NOCICEPTION IN RAT SPINAL-CORD - LOCATION, EFFECTS AND INTERACTIONS WITH MORPHINE. EUR J PHARMACOL, 138(2), 169 - 177.
    • Dickenson AH, Sullivan AF, Knox R, Zajac JM, Roques BP (1987). Opioid receptor subtypes in the rat spinal cord: electrophysiological studies with mu- and delta-opioid receptor agonists in the control of nociception.. Brain Res, 413(1), 36 - 44.
    • Dickenson AH, Sullivan AF, Fournie-Zaluski MC, Roques BP (1987). Prevention of degradation of endogenous enkephalins produces inhibition of nociceptive neurones in rat spinal cord.. Brain Res, 408(1-2), 185 - 191.
    • Dickenson AH, Knox RJ (1987). Antagonism of mu-opioid receptor-mediated inhibitions of nociceptive neurones by U50488H and dynorphin A1-13 in the rat dorsal horn.. Neurosci Lett, 75(2), 229 - 234.
    • Knox RJ, Dickenson AH (1987). Effects of selective and non-selective kappa-opioid receptor agonists on cutaneous C-fibre-evoked responses of rat dorsal horn neurones.. Brain Res, 415(1), 21 - 29.

    1986

    • Dickenson AH, Sullivan A, Feeney C, Fournie-Zaluski MC, Roques BP (1986). Evidence that endogenous enkephalins produce delta-opiate receptor mediated neuronal inhibitions in rat dorsal horn.. Neurosci Lett, 72(2), 179 - 182.
    • DICKENSON AH, GOLDSMITH G (1986). EVIDENCE FOR A ROLE OF 5-HYDROXYTRYPTAMINE IN THE RESPONSES OF RAT RAPHE MAGNUS NEURONS TO PERIPHERAL NOXIOUS STIMULI. NEUROPHARMACOLOGY, 25(8), 863 - 868.
    • Fournié-Zaluski MC, Bourgoin S, Cesselin F, Hamon M, Le Bars D, Dickenson AH, Roques BP (1986). Increase in met-enkephalin level and antinociceptive effects induced by kelatorphan in the rat spinal cord.. NIDA Res Monogr, 75, 454 - 456.
    • Dickenson AH, Sullivan AF (1986). Electrophysiological studies on the effects of intrathecal morphine on nociceptive neurones in the rat dorsal horn.. Pain, 24(2), 211 - 222.
    • Dickenson AH (1986). Enkephalins. A new approach to pain relief?. Nature, 320(6064), 681 - 682. doi:10.1038/320681a0

    1985

    • Dickenson AH, Brewer CM, Hayes NA (1985). Effects of topical baclofen on C fibre-evoked neuronal activity in the rat dorsal horn.. Neuroscience, 14(2), 557 - 562.

    1984

    • DICKENSON AH, GOLDSMITH GE (1984). INVOLVEMENT OF SEROTONIN IN THE RESPONSES OF NEURONS IN RAT RAPHE MAGNUS TO NOXIOUS PERIPHERAL STIMULI. J PHYSIOL-LONDON, 350(MAY), P23 - P23.

    1983

    • Dickenson AH, Le Bars D (1983). Diffuse noxious inhibitory controls (DNIC) involve trigeminothalamic and spinothalamic neurones in the rat.. Exp Brain Res, 49(2), 174 - 180.
    • Dickenson AH, Le Bars D (1983). Morphine microinjections into periaqueductal grey matter of the rat: effects on dorsal horn neuronal responses to C-fibre activity and diffuse noxious inhibitory controls.. Life Sci, 33 Suppl 1, 549 - 552.

    1982

    • Chitour D, Dickenson AH, Le Bars D (1982). Pharmacological evidence for the involvement of serotonergic mechanisms in diffuse noxious inhibitory controls (DNIC).. Brain Res, 236(2), 329 - 337.
    • LEBARS D, DICKENSON AH, BESSON JM (1982). OPIATE ANALGESIA AND DESCENDING CONTROL-SYSTEMS. ADV PAIN RES THER, 5, 341 - 372.
    • DICKENSON AH, CHITOUR D, LEBARS D (1982). INFLUENCE OF SEROTONINERGIC RECEPTOR BLOCKADE ON DIFFUSE NOXIOUS INHIBITORY CONTROLS IN THE RAT. ADV PAIN RES THER, 5, 155 - 160.

    1981

    • Dickenson AH, Rivot JP, Chaouch A, Besson JM, Le Bars D (1981). Diffuse noxious inhibitory controls (DNIC) in the rat with or without pCPA pretreatment.. Brain Res, 216(2), 313 - 321.
    • Dickenson AH, Le Bars D, Besson JM (1981). Endogenous opiates and nociception: a possible functional role in both pain inhibition and detection as revealed by intrathecal naloxone.. Neurosci Lett, 24(2), 161 - 164.
    • Le Bars D, Chitour D, Kraus E, Clot AM, Dickenson AH, Besson JM (1981). The effect of systemic morphine upon diffuse noxious inhibitory controls (DNIC) in the rat: evidence for a lifting of certain descending inhibitory controls of dorsal horn convergent neurones.. Brain Res, 215(1-2), 257 - 274.
    • LEBARS D, DICKENSON AH, RIVOT JP, CHITOUR D, CHAOUCH A, KRAUS E, BESSON JM (1981). ARE BULBO-SPINAL SEROTONERGIC SYSTEMS INVOLVED IN THE DETECTION OF NOCICEPTIVE MESSAGES. J PHYSIOL-PARIS, 77(2-3), 463 - 471.
    • Dawson NJ, Dickenson AH, Hellon RF, Woolf CJ (1981). Inhibitory controls on thermal neurones in the spinal trigeminal nucleus of cats and rats.. Brain Res, 209(2), 440 - 445.
    • Le Bars D, Chitour D, Kraus E, Dickenson AH, Besson JM (1981). Effect of naloxone upon diffuse noxious inhibitory controls (DNIC) in the rat.. Brain Res, 204(2), 387 - 402.
    • Le Bars D, Dickenson AH, Rivot JP, Chitour D, Chaouch A, Kraus E, Besson JM (1981). [Are bulbo-spinal serotonergic systems involved in the detection of nociceptive messages? (author's transl)].. J Physiol (Paris), 77(2-3), 463 - 471.
    • Dickenson AH, Hellon RF, Woolf CJ (1981). Tooth pulp input to the spinal trigeminal nucleus: a comparison of inhibitions following segmental and raphe magnus stimulation.. Brain Res, 214(1), 73 - 87.

    1980

    • Dickenson AH, Le Bars D, Besson JM (1980). Diffuse noxious inhibitory controls (DNIC). Effects on trigeminal nucleus caudalis neurones in the rat.. Brain Res, 200(2), 293 - 305.
    • Le Bars D, Chitour D, Kraus E, Dickenson AH, Besson JM (1980). [Depression by morphine of various descending inhibitory controls modulating the transmission of nociceptive information at the spinal level in the rat].. C R Seances Acad Sci D, 291(4), 433 - 436.
    • Le Bars D, Dickenson AH, Besson JM (1980). Microinjection of morphine within nucleus raphe magnus and dorsal horn neurone activities related to nociception in the rat.. Brain Res, 189(2), 467 - 481.
    • LEBARS D, RIVOT JP, DICKENSON AH, CHAOUCH A, BESSON JM (1980). ROLE OF SEROTONIN IN DIFFUSE INHIBITORY CONTROLS INDUCED BY NOXIOUS STIMULATIONS. CR ACAD SCI D NAT, 290(4), 379 - 382.
    • LEBARS D, CHITOUR D, KRAUS E, DICKENSON AH, BESSON JM (1980). MORPHINE-INDUCED DEPRESSION OF SOME DESCENDING INHIBITORY CONTROLS MODULATING SPINAL TRANSMISSION OF NOCICEPTIVE INFORMATION IN THE RAT. CR ACAD SCI D NAT, 291(4), 433 - 436.
    • DICKENSON AH, HELLON RF, WOOLF CJ (1980). SEGMENTAL AND RAPHE MAGNUS INHIBITION OF TOOTH-PULP EVOKED NEURONAL RESPONSES IN RAT TRIGEMINAL NUCLEUS CAUDALIS. J PHYSIOL-LONDON, 300(MAR), P29 - P29.
    • Le Bars D, Rivot JP, Dickenson AH, Chaouch A, Besson JM (1980). [Role of serotonin in the diffuse inhibitory controls induced by nociceptive stimulation].. C R Seances Acad Sci D, 290(4), 379 - 382.

    1979

    • Dickenson AH, Fardin V, Le Bars D, Besson JM (1979). Antinociceptive action following microinjection of methionine-enkephalin in the nucleus raphe magnus of the rat.. Neurosci Lett, 15(2-3), 265 - 270.
    • Dickenson AH, Oliveras JL, Besson JM (1979). Role of the nucleus raphe magnus in opiate analgesia as studied by the microinjection technique in the rat.. Brain Res, 170(1), 95 - 111.
    • Dickenson AH, Hellon RF, Taylor DC (1979). Facial thermal input to the trigeminal spinal nucleus of rabbits and rats.. J Comp Neurol, 185(1), 203 - 209. doi:10.1002/cne.901850112
    • Le Bars D, Dickenson AH, Besson JM (1979). Diffuse noxious inhibitory controls (DNIC). II. Lack of effect on non-convergent neurones, supraspinal involvement and theoretical implications.. Pain, 6(3), 305 - 327.
    • Le Bars D, Dickenson AH, Besson JM (1979). Diffuse noxious inhibitory controls (DNIC). I. Effects on dorsal horn convergent neurones in the rat.. Pain, 6(3), 283 - 304.

    1978

    • DICKENSON AH, OLIVERAS JL, BESSON JM (1978). ROLE OF RAPHE MAGNUS IN OPIATE ANALGESIA. CR ACAD SCI D NAT, 287(10), 955 - 958.
    • Dickenson AH, Oliveras JL, Besson JM (1978). [Role of the Raphe Magnus nucleus in morphine analgesia : studies with intracerebral microinjections in the rat].. C R Acad Sci Hebd Seances Acad Sci D, 287(10), 955 - 958.

    1977

    • Dickenson AH (1977). Specific responses of rat raphé neurones to skin temperature.. J Physiol, 273(1), 277 - 293.
    • DEAKIN JFW, DICKENSON AH, DOSTROVSKY JO (1977). MORPHINE EFFECTS ON RAT RAPHE MAGNUS NEURONS. J PHYSIOL-LONDON, 267(1), P43 - P44.
    • Deakin JF, Dickenson AH, Dostrovsky JO (1977). Morphine effects on rat raphé magnus neurones [proceedings].. J Physiol, 267(1), 43P - 45P.

    1976

    • DICKENSON AH (1976). NEURONS IN RAPHE NUCLEI OF RAT RESPONDING TO SKIN TEMPERATURE. J PHYSIOL-LONDON, 256(2), P110 - P110.