Contribute to our understanding of the impact of ageing on the immune system

When the human body is confronted with an infection or an injury, the immune system is activated and inflammation can ensue.

As we age, the immune system becomes less effective and the elderly are more susceptible to infections. 

This project aims to further our understanding of the properties of neutrophils, a type of white blood cell that helps fight infection. Previous research has found differences in the way these cells move towards a chemoattractant (the process of chemotaxis), which may explain why the elderly are more prone to infections. Participants are needed to give blood samples to further investigate this phenomenon.

Who is it for?

Health adults who are:

• aged 18-40, or over 65
• non-smokers
• ideally not taking any medication

Some medications may significantly affect outcomes. However, this can be discussed on an individual basis, as some may not have any impact.

What will it involve? 

Participants will be required to give a small volume of blood (20ml) to be studied. The research will take place in the Rayne Building (Centre for Clinical Pharmacology and Therapeutics) and participants will be needed for approximately 15 minutes.

What else do I need to know?

Blood donation is entirely voluntary, and participants will not be reimbursed. Should you wish to take part, you are able to withdraw at any time without giving a reason.  

To find out more, or to take part, contact Nikita Patel. 

This study has been approved by the UCL Research Ethics Committee, reference: BRD/06/132. All the information collected as part of the study will be kept strictly confidential.

Nikita Patel, 4th Year Pharmacology (MSci) student, UCL Department of Neuroscience, Physiology and Pharmacology