Experimental Models

Many different small animal models are used for NCL research. These range from single celled organisms, such as yeasts, through nematode worms or flies, which have simple nervous systems, through to vertebrate fish models.

Each model has its own advantages. These include access to the complete sequence of their genome, their genetic tractability and easily monitored brain development. The use of some of these in NCL research is still under development

List of Models

Budding Yeast - Saccharomyces cerevisiae

Fission Yeast - Schizosaccharonmyces pombe

Nematotode worm - Caenorhabditis elegans

Fly - Drosophila melanogaster

Zebrafish