Animal Models

As well as causing disease in humans, animals also develop NCL. NCL has been described in many species including dogs, cats, sheep, cattle, pigs, mice and birds.

Some of these animals are being studied to understand more about disease progression, and may be used in clinical trials as new therapies are developed. Others are being used to identify new NCL genes that will help to complete the picture in terms of which genes cause NCL. Some genes that cause disease in animals may not cause disease in human patients.

DNA tests are available for these genes to identify carrier animals. Careful breeding prevents the disease being passed onto any offspring.

Dogs

Sheep

Cow

Mouse

Fish