My study is focused on sensory transduction and transmission in peripheral nervous system, especially in pain signalling. I use gene targeting in/transgenic mice as a model, combining molecular biochemistry, electrophysiology and behavioural approaches to identify the genes or molecules involved and to understand the molecular, cellular physiological and pathological mechanisms involved. Currently I am investigating 1) the trafficking of sodium channel Nav1.7, 2) the role of BDNF in chronic pain, 3) the function of microRNA in pain signalling and 4) the role of sodium channel Nav1.8 in cardiac conduction.
Telephone:020 7679 6722, e-Mail: firstname.lastname@example.org
I am an MRC Research Career Development Fellow focussing on the genetic basis of human pain. We study families with rare inherited pain disorders (either with pain insensitivity or chronic pain conditions). By sequencing the genome of our patients with pain disorders we aim to identify novel gene mutations. This enables us to highlight genes and pathways that are critical for normal pain sensation and potentially reveal new analgesic drug targets..
Telephone:020 7679 6704, e-Mail: email@example.com
Dr Ana-Paula Luiz
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Dr Edward Emery
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Dr Shafaq Sikandar
Telephone:020 7679 6722, e-Mail firstname.lastname@example.org
Dr Jane Sexton
Telephone:020 7679 6722, e-Mail email@example.com