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Centre for Molecular Medicine

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Key Publications

1Sewell, G. W., D. J. Marks, and A. W. Segal. 2009. The immunopathogenesis of Crohn's disease: a three-stage model. Curr. Opin. Immunol.
2Smith, A. M., F. Z. Rahman, B. Hayee, S. J. Graham, D. J. Marks, G. W. Sewell, C. D. Palmer, J. Wilde, B. M. Foxwell, I. S. Gloger, T. Sweeting, M. Marsh, A. P. Walker, S. L. Bloom, and A. W. Segal. 2009. Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease. J. Exp. Med. 206:1883.
3Rahman, F. Z., D. J. Marks, B. H. Hayee, A. M. Smith, S. L. Bloom, and A. W. Segal. 2008. Phagocyte dysfunction and inflammatory bowel disease. Inflamm. Bowel. Dis. 14:1443.
4Marks, D. J., M. W. Harbord, R. MacAllister, F. Z. Rahman, J. Young, B. Al-Lazikani, W. Lees, M. Novelli, S. Bloom, and A. W. Segal. 2006. Defective acute inflammation in Crohn's disease: a clinical investigation. Lancet 367:668.
5Segal, A. W. 2005. How neutrophils kill microbes. Annu. Rev. Immunol. 23:197.
6Reeves, E. P., H. Lu, H. L. Jacobs, C. G. Messina, S. Bolsover, G. Gabella, E. O. Potma, A. Warley, J. Roes, and A. W. Segal. 2002. Killing activity of neutrophils is mediated through activation of proteases by K+ flux. Nature 416:291.