Centre for Molecular Medicine


Key Publications

1 Sewell, G. W., D. J. Marks, and A. W. Segal. 2009. The immunopathogenesis of Crohn's disease: a three-stage model. Curr. Opin. Immunol.
2 Smith, A. M., F. Z. Rahman, B. Hayee, S. J. Graham, D. J. Marks, G. W. Sewell, C. D. Palmer, J. Wilde, B. M. Foxwell, I. S. Gloger, T. Sweeting, M. Marsh, A. P. Walker, S. L. Bloom, and A. W. Segal. 2009. Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease. J. Exp. Med. 206:1883.
3 Rahman, F. Z., D. J. Marks, B. H. Hayee, A. M. Smith, S. L. Bloom, and A. W. Segal. 2008. Phagocyte dysfunction and inflammatory bowel disease. Inflamm. Bowel. Dis. 14:1443.
4 Marks, D. J., M. W. Harbord, R. MacAllister, F. Z. Rahman, J. Young, B. Al-Lazikani, W. Lees, M. Novelli, S. Bloom, and A. W. Segal. 2006. Defective acute inflammation in Crohn's disease: a clinical investigation. Lancet 367:668.
5 Segal, A. W. 2005. How neutrophils kill microbes. Annu. Rev. Immunol. 23:197.
6 Reeves, E. P., H. Lu, H. L. Jacobs, C. G. Messina, S. Bolsover, G. Gabella, E. O. Potma, A. Warley, J. Roes, and A. W. Segal. 2002. Killing activity of neutrophils is mediated through activation of proteases by K+ flux. Nature 416:291.