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Prof Stephen Moss

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Personal Profile

Name: Stephen Moss Email: s.moss@ucl.ac.uk
Title: Prof Tel: 020 7608 6973
Department: Inst Ophthalmology - Cell Biology Fax: 020 7608 4034
Position: Ashton Professor of Biomedical Research Address: 11-43 Bath Street, London, London, EC1V 9EL
Research Domain: Ageing, Basic Life Sciences, Biomedical Imaging (Frontier Disciplines), Cardiometabolic Science, Experimental Medicine, Neuroscience, Personalised Medicine Web Page:  

Profile

Research Description

For many years our lab focused on an investigation of proteins of the annexin family. Annexins are an evolutionarily conserved multigene family with multiple roles, and through this work we developed cell biological approaches to vesicle trafficking, phospholipid metabolism, actin dynamics, apoptosis and cell transformation (tumours). More recently the focus in the lab has switched to angiogenesis, and particularly the abnormal pathological angiogenesis that characterises the wet form of age-related macular disease (AMD), and proliferative diabetic retinopathy.

In a project co-directed with John Greenwood we undertook a gene expression analysis of abnormal blood vessels isolated from the retinas of four rodent models of retinal vascular disease. We found a set of genes conserved within these models, several of which were either of unknown function or previously had no known link to angiogenesis. So far we have begun investigations into three of these genes and have identified one as being a critical regulator of the angiogenic activity of TGFbeta. Work on this gene has led to us filing a patent application in regard to its suitability as a target for anti-angiogenic therapies, and in funding obtained from the MRC we are currently developing a blocking monoclonal antibody against this protein that we intend to take to a phase I clinical trial in 2014.

Other work in lab is aimed at understanding the roles of complement proteins and complement-mediated cell attack in the retinal pigment epithelium. This is highly relevant to AMD, where variants in several complement genes are linked to disease susceptibility.


Research Activities

A New Window on to Cellular Mechanisms of Neuronal Apoptosis and Vision Loss in Glaucoma

Angiogenesis

Annexin 2 and Diabetic Retinopathy

Calcium signalling and mitochondrial function in cell physiology and pathophysiology.

Glaucoma & Retinal Neurodegeneration research

Inhibition of angiogenesis

Investigation of the molecular basis of ocular angiogenesis and the development of effective novel therapeutic approaches for patients with ocular neovascular diseases.

Mitochondrial dysfunction

The Cell Biology of Eye Disease

Education Description

UCL Collaborators

Dr Freya Margarete Mowat; Dr Jonathan Gale; Professor Francesca Cordeiro; Prof Clare Futter; Prof David Selwood; Prof Michael Duchen; Dr Marcus Fruttiger; Dr Tim Levine; Prof Tony Schapira; Prof Amit Nathwani; Dr Li Guo; Dr Ilias Tachtsidis

External Collaborators

Publications

    2014

    • Davis BM, Normando EM, Guo L, O'Shea P, Moss SE, Somavarapu S, Cordeiro MF (2014). Topical Delivery of Avastin to the Posterior Segment of the Eye In Vivo Using Annexin A5-associated Liposomes.. Small, , - . doi:10.1002/smll.201303433

    2013

    • Williams JA, Greenwood J, Moss SE (2013). Retinal changes precede visual dysfunction in the complement factor h knockout mouse.. PLoS One, 8(7), e68616 - . doi:10.1371/journal.pone.0068616
    • Wang X, Abraham S, McKenzie JA, Jeffs N, Swire M, Tripathi VB, Luhmann UF, Lange CA, Zhai Z, Arthur HM, Bainbridge JW, Moss SE, Greenwood J (2013). LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling.. Nature, 499(7458), 306 - 311. doi:10.1038/nature12345
    • Chlystun M, Campanella M, Law AL, Duchen MR, Fatimathas L, Levine TP, Gerke V, Moss SE (2013). Regulation of mitochondrial morphogenesis by annexin A6.. PLoS One, 8(1), e53774 - . doi:10.1371/journal.pone.0053774

    2012

    • Cordeiro MF, Moss SE, fitzke FW (2012). FLUORESCENT MARKER FOR CELL DEATH IN THE EYE.
    • Faber C, Williams J, Juel HB, Greenwood J, Nissen MH, Moss SE (2012). Complement Factor H Deficiency Results in Decreased Neuroretinal Expression of Cd59a in Aged Mice. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 53(10), 6324 - 6330. doi:10.1167/iovs.12-10385
    • Grskovic I, Kutsch A, Frie C, Groma G, Stermann J, Schloetzer-Schrehardt U, Niehoff A, Moss SE, Rosenbaum S, Poeschl E, Chmielewski M, Rappl G, Abken H, Bateman JF, Cheah KSE, Paulsson M, Brachvogel B (2012). Depletion of Annexin A5, Annexin A6, and Collagen X Causes No Gross Changes in Matrix Vesicle-Mediated Mineralization, but Lack of Collagen X Affects Hematopoiesis and the Th1/Th2 Response. JOURNAL OF BONE AND MINERAL RESEARCH, 27(11), 2399 - 2412. doi:10.1002/jbmr.1682
    • Moss SE (2012). How actin gets the PIP.. Sci Signal, 5(213), pe7 - . doi:10.1126/scisignal.2002839
    • McKenzie JA, Fruttiger M, Abraham S, Lange CA, Stone J, Gandhi P, Wang X, Bainbridge J, Moss SE, Greenwood J (2012). Apelin is required for non-neovascular remodeling in the retina.. Am J Pathol, 180(1), 399 - 409. doi:10.1016/j.ajpath.2011.09.035
    • Grieve AG, Moss SE, Hayes MJ (2012). Annexin A2 at the interface of actin and membrane dynamics: a focus on its roles in endocytosis and cell polarization. International Journal of Cell Biology, , - . doi:10.1155/2012/852430
    • Minashima T, Small W, Moss SE, Kirsch T (2012). Intracellular Modulation of Signaling Pathways by Annexin A6 Regulates Terminal Differentiation of Chondrocytes. JOURNAL OF BIOLOGICAL CHEMISTRY, 287(18), 14803 - 14815. doi:10.1074/jbc.M111.297861

    2011

    • Carr AJ, Vugler AA, Yu L, Semo M, Coffey P, Moss SE, Greenwood J (2011). The expression of retinal cell markers in human retinal pigment epithelial cells and their augmentation by the synthetic retinoid fenretinide.. Mol Vis, 17, 1701 - 1715.
    • Coxon KM, Duggan J, Cordeiro MF, Moss SE (2011). Purification of annexin V and its use in the detection of apoptotic cells.. Methods Mol Biol, 731, 293 - 308. doi:10.1007/978-1-61779-080-5_24
    • Grieve AG, Daniels RD, Sanchez-Heras E, Hayes MJ, Moss SE, Matter K, Lowe M, Levine TP (2011). Lowe Syndrome protein OCRL1 supports maturation of polarized epithelial cells.. PLoS One, 6(8), e24044 - . doi:10.1371/journal.pone.0024044
    • Cordeiro MF, Migdal C, Bloom P, Fitzke FW, Moss SE (2011). Imaging apoptosis in the eye. EYE, 25(5), 545 - 553. doi:10.1038/eye.2011.64
    • Lueck K, Wasmuth S, Williams J, Hughes TR, Morgan BP, Lommatzsch A, Greenwood J, Moss SE, Pauleikhoff D (2011). Sub-lytic C5b-9 induces functional changes in retinal pigment epithelial cells consistent with age-related macular degeneration. EYE, 25(8), 1074 - 1082. doi:10.1038/eye.2011.109

    2010

    • Hasan SM, Vugler AA, Miljan EA, Sinden JD, Moss SE, Greenwood J (2010). Immortalized human fetal retinal cells retain progenitor characteristics and represent a potential source for the treatment of retinal degenerative disease.. Cell Transplant, 19(10), 1291 - 1306. doi:10.3727/096368910X505477
    • Cordeiro MF, Guo L, Coxon KM, Duggan J, Nizari S, Normando EM, Sensi SL, Sillito AM, Fitzke FW, Salt TE, Moss SE (2010). Imaging multiple phases of neurodegeneration: a novel approach to assessing cell death in vivo. CELL DEATH DIS, 1, - . doi:10.1038/cddis.2009.3
    • Parmalee NL, Schubert C, Merriam JE, Allikmets K, Bird AC, Gillies MC, Peto T, Figueroa M, Friedlander M, Fruttiger M, Greenwood J, Moss SE, Smith LEH, Toomes C, Inglehearn CF, Allikmets R (2010). Analysis of candidate genes for macular telangiectasia type 2. MOL VIS, 16(289-90), 2718 - 2726.
    • Parmalee NL, Schubert C, Merriam JE, Allikmets K, Bird AC, Gillies MC, Peto T, Figueroa M, Friedlander M, Fruttiger M, Greenwood J, Moss SE, Smith LEH, Toomes C, Inglehearn CF, Allikmets R (2010). Analysis of candidate genes for macular telangiectasia type 2. MOL VIS, 16(189-90), 2718 - 2726.
    • Fatimathas L, Moss SE (2010). Annexins as disease modifiers.. Histol Histopathol, 25(4), 527 - 532.

    2009

    • Fatimathas L, Moss SE (2009). Characterisation of the sarcoidosis-associated variant of annexin A11.
    • Hayes MJ, Shao DM, Grieve A, Levine T, Bailly M, Moss SE (2009). Annexin A2 at the interface between F-actin and membranes enriched in phosphatidylinositol 4,5,-bisphosphate. Biochim.Biophys.Acta, 1793(6), 1086 - 1095.
    • Longbottom R, Fruttiger M, Douglas RH, Martinez-Barbera JP, Greenwood J, Moss SE (2009). Genetic ablation of retinal pigment epithelial cells reveals the adaptive response of the epithelium and impact on photoreceptors.. Proc Natl Acad Sci U S A, 106(44), 18728 - 18733. doi:10.1073/pnas.0902593106
    • Schmitz-Valckenberg S, Guo L, Cheung W, Moss SE, Fitzke FW, Cordeiro MF (2009). [In vivo imaging of retinal cell apoptosis following acute light exposure.]. Ophthalmologe, , - .
    • Belluoccio D, Grskovic I, Niehoff A, Schlotzer-Schrehardt U, Rosenbaum S, Etich J, Frie C, Pausch F, Moss SE, Poschl E, Bateman JF, Brachvogel B (2009). Deficiency of Annexins A5 and A6 Induces Complex Changes in the Transcriptome of Growth Plate Cartilage, But Does Not Inhibit the Induction of Mineralisation. J.Bone Miner.Res., , - .
    • Hayes MJ, Moss SE (2009). Annexin 2 has a dual role as regulator and effector of v-Src in cell transformation. J.Biol.Chem., 284(15), 10202 - 10210.
    • Law AL, Ling Q, Hajjar KA, Futter CE, Greenwood J, Adamson P, Wavre-Shapton ST, Moss SE, Hayes MJ (2009). Annexin A2 Regulates Phagocytosis of Photoreceptor Outer Segments in the Mouse Retina. Mol.Biol.Cell, , - .

    2008

    • Hayes MJ, Shao DM, Grieve A, Levine T, Bailly M, Moss SE (2008). Annexin A2 at the interface between F-actin and membranes enriched in phosphatidylinositol 4,5,-bisphosphate. Biochim.Biophys.Acta, , - .
    • Schmitz-Valckenberg S, Guo L, Maass A, Cheung W, Vugler A, Moss SE, Munro PM, Fitzke FW, Cordeiro MF (2008). Real-time in vivo imaging of retinal cell apoptosis after laser exposure.. Investigative Ophthalmology and Visual Science, 49(6), 2773 - 2280.
    • Hastie C, Masters JR, Moss SE, Naaby-Hansen S (2008). Interferon-gamma reduces cell surface expression of annexin 2 and suppresses the invasive capacity of prostate cancer cells. Journal of Biological Chemistry, 283, 12595 - 12603.
    • Ghazi-Nouri SM, Ellis JS, Moss S, Limb GA, Charteris DG (2008). Expression and localisation of BDNF, NT4 and TrkB in proliferative vitreoretinopathy. Exp.Eye Res., 86(5), 819 - 827.
    • Hastie C, Masters JR, Moss SE, Naaby-Hansen S (2008). IFN-I reduces cell surface expression of annexin 2 and suppresses the invasive capacity of prostate cancer cells. J Biol Chem, , 12595 - 12603.

    2007

    • Kim H, Moss SE, Kirsch T (2007). Loss of annexin VI affects endochondral bone formation.
    • Guo L, Salt TE, Luong V, Wood N, Cheung W, Maass A, Ferrari G, Russo-Marie F, Sillito AM, Cheetham ME, Moss SE, Fitzke FW, Cordeiro M (2007). Targeting amyloid-β in glaucoma treatment. Proceedings of the National Academy of Sciences of the United States of America, 104(33), 13444 - 13449. doi:10.1073/pnas.0703707104
    • Hayes MJ, Longbottom RE, Evans MA, Moss SE (2007). Annexinopathies. Subcell.Biochem., 45, 1 - 28.
    • Peters S, Cree IA, Alexander R, Turowski P, Ockrim Z, Patel J, Boyd SR, Joussen AM, Ziemssen F, Hykin PG, Moss SE (2007). Angiopoietin modulation of vascular endothelial growth factor: Effects on retinal endothelial cell permeability.. Cytokine, 40(2), 144 - 150.
    • Coffey PJ, Gias C, McDermott CJ, Lundh P, Pickering MC, Sethi C, Bird A, Fitzke FW, Maass A, Chen LL, Holder GE, Luthert PJ, Salt TE, Moss SE, Greenwood J (2007). Complement factor H deficiency in aged mice causes retinal abnormalities and visual dysfunction. Proceedings of the National Academy of Sciences of the United States of America, 104(42), 16651 - 16656. doi:10.1073/pnas.0705079104
    • Psatha MI, Razi M, Koffer A, Moss SE, Sacks DB, Bolsover SR (2007). Targeting of calcium:calmodulin signals to the cytoskeleton by IQGAP1. Cell Calcium, 41, 593 - 605. doi:10.1016/j.ceca.2006.10.009

    2006

    • Moss SE, Gerke V (2006). Meeting Report: 9th European Symposium on Calcium. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1763(11), 1136 - 1138.
    • Guo L, Salt TE, Maass A, Luong V, Moss SE, Fitzke FW, Cordeiro MF (2006). Assessment of neuroprotective effects of glutamate modulation on glaucoma-related retinal ganglion cell apoptosis in vivo. Investigative Ophthalmology and Visual Science, 47(2), 626 - 633.
    • Hayes MJ, Shao DM, Bailly M, Moss SE (2006). Regulation of actin dynamics by annexin 2. EMBO J, 25(9), 1816 - 1826. doi:10.1038/sj.emboj.761078
    • Hayes MJ, Shao D, Bailly M, Moss SE (2006). Regulation of actin dynamics by annexin 2. The EMBO Journal, 25(9), 1816 - 1826. doi:10.1038/sj.emboj.7601078
    • White IJ, Bailey LM, Razi Aghakhani M, Moss SE, Futter CE (2006). EGF stimulates annexin 1-dependent inward vesiculation within a sub-population of multivesicular endosomes.. The EMBO Journal, 25(1), 1 - 12. doi:10.1038/sj.emboj.7600759

    2005

    • Guo L, Moss SE, Alexander RA, Ali R, Fitzke F, Cordeiro MF (2005). Retinal ganglion cell apoptosis in glaucoma is related to intraocular pressure and IOP-induced effects on extracellular matrix. Investigative Ophthalmology and Visual Science, 46(1), 175 - 182. doi:10.1167/iovs.04-0832
    • Guo L, Salt TE, Maass A, Luong V, Moss SE, Fitzke FW, Cordeiro MF (2005). Activation of group II mGlu receptors is neuroprotective in retinal ganglion cell apoptosis in in vivo models of glaucoma.
    • Lievremont JP, Numaga T, Vazquez G, Lemonnier L, Hara Y, Mori E, Trebak M, Moss SE, Bird GS, Mori Y, Putney JW, Jr (2005). The role of canonical transient receptor potential 7 in B-cell receptor-activated channels. J BIOL CHEM, 280(42), 35346 - 35351.
    • Gerke V, Creutz CE, Moss SE (2005). Annexins: linking Ca2+ signalling to membrane dynamics. NAT REV MOL CELL BIOL, 6(6), 449 - 461.

    2004

    • Hayes MJ, Merrifield CJ, Shao D, Ayala-Sanmartin J, Schorey CD, Levine TP, Proust J, Curran J, Bailly M, Moss SE (2004). Annexin 2 binding to phosphatidylinositol 4,5-bisphosphate on endocytic vesicles is regulated by the stress response pathway.. Journal of Biological Chemistry, 279(14), 14157 - 14164.
    • Tomas A, Futter C, Moss SE (2004). Annexin 11 is required for midbody formation and completion of the terminal phase of cytokinesis.. The Journal of cell biology, 165(6), 813 - 822. doi:10.1083/jcb.200311054
    • Moss SE, Morgan RO (2004). The annexins.. Genome Biology, 5(4), 219 - .
    • Hayes MJ, Rescher U, Gerke V, Moss SE (2004). Annexin-actin interactions.. Traffic, 5(8), 571 - 576.
    • Cordeiro MF, Guo L, Luong V, Harding G, Wang W, Jones HE, Moss SE, Sillito AM, Fitzke FW (2004). Real-time imaging of single nerve cell apoptosis in retinal neurodegeneration.. Proceedings of the National Academy of Sciences of the United States of America, 101(36), 13352 - 13356. doi:10.1073/pnas.0405479101
    • Cordeiro MF, Guo L, Luong V, Harding G, Wang W, Jones HE, Moss SE, Sillito AM, Fitzke FW (2004). Real-time imaging of single nerve cell apoptosis in retinal neurodegeneration. P NATL ACAD SCI USA, 101(36), 13352 - 13356. doi:10.1079/pnas.0405479101
    • Hayes MJ, Moss SE (2004). Annexins and disease.. Biochemical and Biophysical Research Communications, 322(4), 1166 - 1170.
    • Ahir A, Cammer M, Condeelis J, Moss SE, Khaw PT, Bailly M (2004). Sequential cell mediated contractile activity and MMP-mediated physical and chemical matrix remodelling define two distinct phases in tissue contraction.
    • Turowski P, Adamson P, Sathia J, Zhang JJ, Moss SE, Aylward GW, Hayes MJ, Kanuga N, Greenwood J (2004). Basement membrane-dependent modification of phenotype and gene expression in human retinal pigment epithelial ARPE-19 cells.. Investigative Ophthalmology and Visual Science, 45(8), 2786 - 2794. doi:10.1167/iovs.03-0943
    • Moss SE (2004). Small change.. Nature, 428(6982), 467 - .
    • Peters S, Cree IA, Hykin PG, Moss SE (2004). Angiopoietin-2 multiplies the permeability-enhancing effect of Vascular Endothelial Growth Factor on retinal endothelial cells.
    • Psatha M, Koffer A, Erent M, Moss SE, Bolsover S (2004). Calmodulin spatial dynamics in RBL-2H3 mast cells.. Cell Calcium, 36(1), 51 - 59. doi:10.1016/j.ceca.2003.11.009

    2003

    • Hillman KA, Harada H, Chan CM, Townsend-Nicholson A, Moss SE, Miyamoto K, Suketa Y, Burnstock G, Unwin RJ, Dunn PM (2003). Chicken DT40 cells stably transfected with the rat P2X7 receptor ion channel: a system suitable for the study of purine receptor-mediated cell death. Biochemical Pharmacology, 66(3), 415 - 424.
    • Draeger A, Monastyrskaya K, Burkhard FC, Wobus AM, Moss SE, Babiychuk EB (2003). Membrane segregation and downregulation of raft markers during sarcolemmal differentiation in skeletal muscle cells. Developmental Biology, 262(2), 324 - 334.
    • Ahir A, Moss SE, Khaw PT, Bailly M (2003). Cell motility and extracellular matrix remodelling during cell mediated collagen contraction - The effect of matrix metalloproteinase modulation.
    • Moss SE (2003). Annexins and calcium signaling. In Bradshaw RA, Dennis E (Ed.), Handbook of Cellular Signaling (pp. 101 - 103). : Elsevier Science.
    • Tomas A, Hayes MJ, Das D, Young BP, Moss SE (2003). Annexin gene knock-out models. In Bandorowicz-Pikula J (Ed.), Annexins: Biological Importance and Annexin-Related Pathologies (pp. 79 - 85). : Landes Press.
    • Tomas A, Moss SE (2003). Calcium- and cell cycle-dependent association of annexin 11 with the nuclear envelope. Journal of Biological Chemistry, 278(22), 20210 - 20216.

    2002

    • Limb GA, Salt TE, Munro PM, Moss SE, Khaw PT (2002). In vitro characterization of a spontaneously immortalized human Muller cell line (MIO-M1). Investigative Ophthalmology and Visual Science, 43(3), 864 - 869.
    • Song G, Harding SE, Duchen MR, Tunwell R, O'Gara P, Hawkins TE, Moss SE (2002). Altered mechanical properties and intracellular calcium signaling in cardiomyocytes from annexin 6 null-mutant mice. The FASEB Journal, 16(6), 622 - 624.
    • Sacre SM, Moss SE (2002). Intracellular localization of endothelial cell annexins is differentially regulated by oxidative stress. Experimental Cell Research, 274(2), 254 - 263.
    • Gerke V, Moss SE (2002). Annexins: from structure to function. Physiological Reviews, 82(2), 331 - 371.
    • Hawkins TE, Das D, Young B, Moss SE (2002). DT40 cells lacking the Ca2+-binding protein annexin 5 are resistant to Ca2+-dependent apoptosis. Proceedings of the National Academy of Sciences of the United States of America, 99(12), 8054 - 8059. doi:10.1073/pnas.132598099
    • Moss SE, Rubin G, Greenwood J, Sillito A (2002). UK government closes its eyes to medical needs. Nature, 420(6913), 268 - .

    2001

    • Merrifield CJ, Rescher U, Almers W, Proust J, Gerke V, Sechi AS, Moss SE (2001). Annexin 2 has an essential role in actin-based macropinocytic rocketing. Current Biology, 11(14), 1136 - 1141. doi:10.1016/S0960-9822(01)00321-9
    • Song GJ, Hawkins TE, Moss SE (2001). Targeted disruption of the annexin 6 gene improves resistance to hypoxia injury in the adult mice cardiaomyocyte. CIRCULATION, 104(17), 201 - 201.
    • Moss SE (2001). Speak out against wrong done in your name. Nature, 414(6862), 393 - 393.

    2000

    • Song G, Tunwell RE, Hawkins TE, Moss SE (2000). Increased cardiac expression of the Na+/Ca2+ exchanger may be responsible for altered myocyte intracellular Ca2+ cycling in mice with targeted disruption of the annexin-6 gene. CIRCULATION, 102(18), 141 - 141.
    • (2000). Annexins and membrane fusion. Subcellular Biochemistry, 34, 73 - 131.
    • (2000). Calcium signaling and annexins. Cell Biochemistry and Biophysics, 33(3), 275 - 296.
    • Song G, Tunwell REA, Hawkins TE, Moss SE (2000). Increased cardiac expression of the Na+/Ca2+ exchanger may be responsible for altered myocyte intracellular Ca2+ cycling in mice with targeted disruption of the annexin-6 gene.

    1999

    • Song GJ, Harding SE, Duchen M, O'Gara P, Hawkins T, Moss SE (1999). Altered cardiomyocyte dynamics in annexin VI knockout mice. CIRCULATION, 100(18), 762 - 763.
    • (1999). Inhibition of EGF-dependent calcium influx by annexin VI is splice-form specific. Biochemical and Biophysical Research Communications, 260, 540 - 546.
    • (1999). Immunological development and cardiovascular function are normal in annexin VI null mutant mice. Molecular and Cellular Biology, 19, 8028 - 8032.
    • (1999). Endocytic vesicles move at the tips of actin tails after they bud from the plasma membrane of cultured mast cells. Nature Cell Biology, 1, 72 - 74.
    • Kubista H, Hawkins TE, Patel DR, Haigler HT, Moss SE (1999). Annexin 5 mediates a peroxide-induced Ca2+ influx in B cells. Current Biology, 9, 1403 - 1406.
    • Kubista H, Hawkins TE, Patel DR, Haigler HT, Moss SE (1999). Annexin 5 mediates a peroxide-induced Ca(2+) influx in B cells.. Curr Biol, 9(23), 1403 - 1406.
    • Merrifield CJ, Moss SE, Ballestrem C, Imhof BA, Giese G, Wunderlich I, Almers W (1999). Endocytic vesicles move at the tips of actin tails in cultured mast cells.. Nat Cell Biol, 1(1), 72 - 74. doi:10.1038/9048
    • (1999). A conserved nuclear element with a role in mammalian gene regulation. Human Molecular Genetics, 8, 1723 - 1728.
    • Donnelly SR, Hawkins TE, Moss SE (1999). A conserved nuclear element with a role in mammalian gene regulation. Human Molecular Genetics, 8, 1723 - 1728.
    • Ashmore JF, Bolsover SR, Cockcroft S, Duchen MR, Koffer A, Moss SE, Swann K (1999). Imaging as applied to cell signalling: work from the Physiology Imaging Consortium (UCL.PIC).
    • Dunn PM, Burnstock G, Unwin R, Moss SE, Chan CM (1999). Properties of the rat P2X7 receptor stably expressed in chicken DT40 cells.

    1998

    • Hawkins TE, Roes J, Moss SE (1998). Targeted disruption of annexin VI in mice.
    • Kubista H, Hawkins T, Moss SE (1998). Characterisation of calcium signalling in DT40 chicken B-cells. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1448(2), 299 - 310.
    • Chan CM, Hillman K, Moss S, Unwin RJ, Burnstock G (1998). Putative cytolytic P2X7 receptor in diabetic rat kidney and its stable transfection in lymphocytes.
    • Donnelly SR, Moss SE (1998). Functional analysis of the human annexin I and VI gene promotors. Biochemical Journal, 332, 681 - 687.
    • Kubista H, Hawkins T, Moss SE (1998). Dependency of Ca2+ signalling on growth conditions in B cells.
    • Sacre SM, Moss SE (1998). Differential responses of endothelial cell annexins I and II to calcium-mobilising agonists.

    1997

    • Gilfillan I, Moss SE (1997). The src-family and the cell cycle.
    • Donnelly SR, Moss SE (1997). Annexins: Gene regulation and function.. FASEB J, 11(9), A1202 - A1202.
    • Donnelly SR, Moss SE (1997). Steroid induction of the annexin I and VI promoters.
    • Donnelly SR, Moss SE (1997). Regulation of annexin I and VI gene expression by steroids.
    • Hawkins T, Moss SE (1997). Investigation of annexin function by targeted disruption in a chick pre-B-cell line.
    • Merrifield C, Moss SE (1997). Imaging of annexin II in living cells.
    • Donnelly SR, Moss SE (1997). Annexins in the secretory pathway. Cellular and Molecular Life Sciences, 53, 533 - 538.
    • Gerke V, Moss SE (1997). Annexins and membrane dynamics. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1357, 129 - 154.
    • Moss SE (1997). Annexins. Trends in Cell Biology, 7, 87 - 89.
    • Gilfillan I, Moss SE (1997). The Src-family and the cell cycle. FASEB J, 11(9), A1388 - A1388.

    1996

    • Francia G, Mitchell SD, Moss SE, Hanby AM, Marshall JF, Hart IR (1996). Identification by differential display of annexin-VI, a gene differentially expressed during melanoma progression. CANCER RES, 56(17), 3855 - 3858.

    1995

    • Theobald J, Hanby A, Patel K, Moss SE (1995). Annexin VI has tumour-suppressor activity in human A431 squamous epithelial carcinoma cells.. Br J Cancer, 71(4), 786 - 788.
    • DUBOIS T, SOULA M, MOSS SE, RUSSOMARIE F, ROTHHUT B (1995). POTENTIAL INTERACTION BETWEEN ANNEXIN-VI AND A 56-KDA PROTEIN-KINASE IN T-CELLS. BIOCHEM BIOPH RES CO, 212(1), 270 - 278.
    • Edwards HC, Moss SE (1995). Functional and genetic analysis of annexin VI.. Mol Cell Biochem, 149-150, 293 - 299.
    • Churcher Y, Moss SE (1995). Inhibition of interleukin-2-mediated DNA synthesis in activated human T-lymphoblasts by okadaic acid is accompanied by hyperphosphorylation of lck.. Biochem J, 308 ( Pt 3), 777 - 783.

    1994

    • Theobald J, Smith PD, Jacob SM, Moss SE (1994). Expression of annexin VI in A431 carcinoma cells suppresses proliferation: a possible role for annexin VI in cell growth regulation.. Biochim Biophys Acta, 1223(3), 383 - 390.
    • Upton AL, Moss SE (1994). Molecular cloning of a novel N-terminal variant of annexin II from rat basophilic leukaemia cells.. Biochem J, 302 ( Pt 2), 425 - 428.
    • Smith PD, Davies A, Crumpton MJ, Moss SE (1994). Structure of the human annexin VI gene.. Proc Natl Acad Sci U S A, 91(7), 2713 - 2717.
    • SMITH PD, MOSS SE (1994). Z-DNA-FORMING SEQUENCES AT A PUTATIVE DUPLICATION SITE IN THE HUMAN ANNEXIN VI-ENCODING GENE. GENE, 138(1-2), 239 - 242.
    • Smythe E, Smith PD, Jacob SM, Theobald J, Moss SE (1994). Endocytosis occurs independently of annexin VI in human A431 cells.. J Cell Biol, 124(3), 301 - 306.
    • Smith PD, Moss SE (1994). Structural evolution of the annexin supergene family.. Trends Genet, 10(7), 241 - 246.
    • Shen WJ, Avery J, Totty NF, Hsuan JJ, Whitaker M, Moss SE (1994). Identification and partial sequence analysis of novel annexins in Lytechinus pictus oocytes. Biochemical Journal, 304(3), 911 - 916.

    1992

    • Moss SE, Jacob SM, Davies AA, Crumpton MJ (1992). A growth-dependent post-translational modification of annexin VI.. Biochim Biophys Acta, 1160(1), 120 - 126.
    • Upton AL, Moss SE (1992). Calcium-binding proteins: beyond hands and loops.. Trends Cell Biol, 2(6), 175 - 176.