RU

Mitochondrial Research Group

If you are at UCL and interested in working with the CfMR, please email Michael Duchen

Prof Robert Unwin

Personal Profile

Name:	Robert Unwin	Email:	robert.unwin@ucl.ac.uk
Title:	Prof	Tel:	0044 207 472 6499
Department:	Internal Medicine	Fax:	0044 0207 472 6476
Position:	Professor of Nephrology and Physiology	Address:	Centre for Nephrology, Royal Free Campus, Rowland Hill Street, London, NW3 2PF
Research Domain:		Web Page:

Profile

Research Description

Most aspects of renal and gastrointestinal transport physiology, especially in a clinical context. These include regulation of potassium and acid-base transport, with relevance to renal 'tubulopathies' and renal stone disease; gut phosphate and glucose absorption in health and disease.
Methods of studying renal tubular function, including micropuncture and microperfusion techniques, and developing ultramicroanalytical methods to facilitate the application of these techniques.
Analytical methods include proteomics, NMR, and mid-infrared spectroscopy as applied to the kidney in biomarker detection and in tubular diseases, e.g., the renal Fanconi syndrome.
Three main themes at present are:
(1) The function of the renal P2 purinoceptor system; its role in transport regulation and some forms of renal disease.
(2) Humoral control of gastrointestinal transport of phosphate and its relationship to changes in renal function.
(3) Renal glucose transport in diabetes.

Research Activities

Diseases of the kidney

Mechanisms and regulation of cellular iron, glucose and phosphate transport

Nephro-Urology

Purinergic Transmission

Renal tubular physiology and the regulation of ion transport

Education Description

I teach medical (and science) undergraduates and postgraduates, and I run an annual national course in applied renal physiology and pathophysiology for clinical postgraduate trainees and interested specialists.

UCL Collaborators

Prof Kevin Moore; Dr Brian King; Prof John Porter; Prof Alan Phillips; Prof Alexander Howie; Prof Patrick Maxwell; Dr Andrea Townsend-Nicholson; Dr David Wheeler; Dr Joanne Marks; Prof Surjit Srai

External Collaborators

Publications

2013

Fish RS, Klootwijk E, Tam FW, Kleta R, Wheeler DC, Unwin RJ, Norman J (2013). ATP and arterial calcification. European Journal of Clinical Investigation, Epub ahead of print, - . doi:10.1111/eci.12055
Jacquillet G, Hoorn EJ, Vilasi A, Unwin RJ (2013). Urinary vesicles: in splendid isolation.. Nephrol Dial Transplant, , - . doi:10.1093/ndt/gfs599
Marks J, Debnam ES, Unwin RJ (2013). The role of the gastrointestinal tract in phosphate homeostasis in health and chronic kidney disease.. Curr Opin Nephrol Hypertens, 22(4), 481 - 487. doi:10.1097/MNH.0b013e3283621310
Deplano S, Cook HT, Russell R, Franchi L, Schneiter S, Bhangal G, Unwin RJ, Pusey CD, Tam FW, Behmoaras J (2013). P2X7 receptor-mediated Nlrp3-inflammasome activation is a genetic determinant of macrophage-dependent crescentic glomerulonephritis.. J Leukoc Biol, 93(1), 127 - 134. doi:10.1189/jlb.0612284
Jacquillet G, Chichger H, Unwin RJ, Shirley DG (2013). Protease stimulation of renal sodium reabsorption in vivo by activation of the collecting duct epithelial sodium channel (ENaC).. Nephrol Dial Transplant, 28(4), 839 - 845. doi:10.1093/ndt/gfs486

2012

Norden AG, Unwin RJ (2012). Is the albumin retrieval hypothesis a paradigm shift for nephrology?. J Am Soc Nephrol, 23(4), 569 - 571. doi:10.1681/ASN.2012020207
Louis-Dit-Picard H, Barc J, Trujillano D, Miserey-Lenkei S, Bouatia-Naji N, Pylypenko O, Beaurain G, Bonnefond A, Sand O, Simian C, Vidal-Petiot E, Soukaseum C, Mandet C, Broux F, Chabre O, Delahousse M, Esnault V, Fiquet B, Houillier P, Bagnis CI, Koenig J, Konrad M, Landais P, Mourani C, Niaudet P, Probst V, Thauvin C, Unwin RJ, Soroka SD, Ehret G, Ossowski S, Caulfield M, Bruneval P, Estivill X, Froguel P, Hadchouel J, Schott JJ, Jeunemaitre X (2012). KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron.. Nat Genet, 44(5), 609 - . doi:10.1038/ng0512-609
Louis-Dit-Picard H, Barc J, Trujillano D, Miserey-Lenkei S, Bouatia-Naji N, Pylypenko O, Beaurain G, Bonnefond A, Sand O, Simian C, Vidal-Petiot E, Soukaseum C, Mandet C, Broux F, Chabre O, Delahousse M, Esnault V, Fiquet B, Houillier P, Bagnis CI, Koenig J, Konrad M, Landais P, Mourani C, Niaudet P, Probst V, Thauvin C, Unwin RJ, Soroka SD, Ehret G, Ossowski S, Caulfield M, International Consortium for Blood Pressure (ICBP) , Bruneval P, Estivill X, Froguel P, Hadchouel J, Schott JJ, Jeunemaitre X (2012). KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron.. Nat Genet, 44(4), 456 - S3. doi:10.1038/ng.2218
Williams EL, Bockenhauer D, van't Hoff WG, Johri N, Laing C, Sinha MD, Unwin R, Viljoen A, Rumsby G (2012). The enzyme 4-hydroxy-2-oxoglutarate aldolase is deficient in primary hyperoxaluria type 3.. Nephrol Dial Transplant, 27(8), 3191 - 3195. doi:10.1093/ndt/gfs039
Jaureguiberry G, De la Dure-Molla M, Parry D, Quentric M, Himmerkus N, Koike T, Poulter J, Klootwijk E, Robinette SL, Howie AJ, Patel V, Figueres ML, Stanescu HC, Issler N, Nicholson JK, Bockenhauer D, Laing C, Walsh SB, McCredie DA, Povey S, Asselin A, Picard A, Coulomb A, Medlar AJ, Bailleul-Forestier I, Verloes A, Le Caignec C, Roussey G, Guiol J, Isidor B, Logan C, Shore R, Johnson C, Inglehearn C, Al-Bahlani S, Schmittbuhl M, Clauss F, Huckert M, Laugel V, Ginglinger E, Pajarola S, Spartà G, Bartholdi D, Rauch A, Addor MC, Yamaguti PM, Safatle HP, Acevedo AC, Martelli-Júnior H, dos Santos Netos PE, Coletta RD, Gruessel S, Sandmann C, Ruehmann D, Langman CB, Scheinman SJ, Ozdemir-Ozenen D, Hart TC, Hart PS, Neugebauer U, Schlatter E, Houillier P, Gahl WA, Vikkula M, Bloch-Zupan A, Bleich M, Kitagawa H, Unwin RJ, Mighell A, Berdal A, Kleta R (2012). Nephrocalcinosis (enamel renal syndrome) caused by autosomal recessive FAM20A mutations.. Nephron Physiol, 122(1-2), 1 - 6. doi:10.1159/000349989
Girfoglio D, Allen D, Kirkham A, Johri N, Wheeler DC, Choong S, Moochhala S, Unwin R (2012). CT SCAN EVALUATION OF PAPILLARY DENSITY IN HYPERCALCIURIC AND NON-HYPERCALCIURIC STONE FORMERS.
Vilasi A, Deplano S, Deplano S, Cutillas P, Unwin R, Tam FWK (2012). PHOSPHOPROTEOMIC ANALYSIS OF THE P2X7 SIGNALLING CASCADE IN MACROPHAGES: A PUTATIVE ROLE IN GLOMERULONEPHRITIS.
Kennedy-Lydon TM, Crawford C, Sawbridge L, Unwin RJ, Wildman SSP, Peppiatt-Wildman CM (2012). Inhibition of medullary prostaglandin E2 (PGE2) by non-steroidal anti-inflammatory drugs (NSAIDs) adversely affects medullary blood flow.
Chichger H, Marks J, Srai SK, Debnam ES, Unwin RJ (2012). Modulation of renal glucose transport by sweet taste sensing at the proximal tubule brush border membrane..
Goodlad C, Unwin R, Reaich D, Cross J (2012). Truly resistant hypertension?. BMJ Case Rep, 2012, - . doi:10.1136/bcr-2012-007396
Booth JW, Tam FW, Unwin RJ (2012). P2 purinoceptors: Renal pathophysiology and therapeutic potential.. Clin Nephrol, 78(2), 154 - 163.
Crawford C, Kennedy-Lydon T, Sprott C, Desai T, Sawbridge L, Munday J, Unwin RJ, Wildman SS, Peppiatt-Wildman CM (2012). An intact kidney slice model to investigate vasa recta properties and function in situ.. Nephron Physiol, 120(3), p17 - p31. doi:10.1159/000339110
Unwin RJ (2012). Back to the future: renal tubular acidosis then and now.. QJM, 105(9), 915 - 916. doi:10.1093/qjmed/hcs134
Wong YF, Wilson PD, Unwin RJ, Norman JT, Arno M, Hendry BM, Xu Q (2012). Retinoic acid receptor-dependent, cell-autonomous, endogenous retinoic acid signaling and its target genes in mouse collecting duct cells.. PLoS One, 7(9), e45725 - . doi:10.1371/journal.pone.0045725
Khositseth S, Bruce LJ, Walsh SB, Bawazir WM, Ogle GD, Unwin RJ, Thong M-K, Sinha R, Choo KE, Chartapisak W, Kingwatanakul P, Sumboonnanonda A, Vasuvattakul S, Yenchitsomanus P, Wrong O (2012). Tropical distal renal tubular acidosis: clinical and epidemiological studies in 78 patients. QJM-AN INTERNATIONAL JOURNAL OF MEDICINE, 105(9), 861 - 877. doi:10.1093/qjmed/hcs139
Walsh SB, Unwin RJ (2012). Renal tubular disorders.. Clin Med, 12(5), 476 - 479.
Scheinman SJ, Feehally J, Feest TG, Norden AG, Thakker RV, Unwin RJ (2012). In memoriam: Oliver M. Wrong.. Kidney Int, 82(2), 121 - 122. doi:10.1038/ki.2012.183
Wang YM, McRae JL, Robson SC, Cowan PJ, Zhang GY, Hu M, Polhill T, Wang Y, Zheng G, Wang Y, Lee VW, Unwin RJ, Harris DC, Dwyer KM, Alexander SI (2012). Regulatory T cells participate in CD39-mediated protection from renal injury.. Eur J Immunol, 42(9), 2441 - 2451. doi:10.1002/eji.201242434
Hoorn EJ, Walsh SB, McCormick JA, Zietse R, Unwin RJ, Ellison DH (2012). Pathogenesis of calcineurin inhibitor-induced hypertension.. J Nephrol, 25(3), 269 - 275. doi:10.5301/jn.5000174
Garcia-Perez I, Villaseñor A, Wijeyesekera A, Posma JM, Jiang Z, Stamler J, Aronson P, Unwin R, Barbas C, Elliott P, Nicholson J, Holmes E (2012). Urinary metabolic phenotyping the slc26a6 (chloride-oxalate exchanger) null mouse model.. J Proteome Res, 11(9), 4425 - 4435. doi:10.1021/pr2012544
Hoorn EJ, Walsh SB, Unwin RJ, Ellison DH (2012). Hypertension after kidney transplantation: calcineurin inhibitors increase salt-sensitivity.. J Hypertens, 30(4), 832 - 833. doi:10.1097/HJH.0b013e32835165e4

2011

Norden AG, Laing RJ, Rowe P, Unwin RJ, Wrong O, Crisp AJ (2011). Oncogenic osteomalacia, raised FGF-23, and renal Fanconi syndrome.. QJM, , - . doi:10.1093/qjmed/hcr247
Bueter M, Ashrafian H, Frankel AH, Tam FW, Unwin RJ, le Roux CW (2011). Sodium and water handling after gastric bypass surgery in a rat model.. Surg Obes Relat Dis, 7(1), 68 - 73. doi:10.1016/j.soard.2010.03.286
Evan AP, Unwin RJ, Williams JC (2011). Renal stone disease: a commentary on the nature and significance of Randall's plaque.. Nephron Physiol, 119(4), p49 - p53. doi:10.1159/000330255
Bueter M, Miras AD, Chichger H, Fenske W, Ghatei MA, Bloom SR, Unwin RJ, Lutz TA, Spector AC, le Roux CW (2011). Alterations of Sucrose Preference after Roux-En-Y Gastric Bypass.
Jacquillet G, Rubera I, Unwin RJ (2011). Potential role of serine proteases in modulating renal sodium transport in vivo.. Nephron Physiol, 119(2), p22 - p29. doi:10.1159/000328926
Bueter M, Miras AD, Chichger H, Fenske W, Ghatei MA, Bloom SR, Unwin RJ, Lutz TA, Spector AC, le Roux CW (2011). Alterations of sucrose preference after Roux-en-Y gastric bypass.. Physiol Behav, 104(5), 709 - 721. doi:10.1016/j.physbeh.2011.07.025
Hall AM, Crawford C, Unwin RJ, Duchen MR, Peppiatt-Wildman CM (2011). Multiphoton imaging of the functioning kidney.. J Am Soc Nephrol, 22(7), 1297 - 1304. doi:10.1681/ASN.2010101054
Walsh SB, Unwin E, Vargas-Poussou R, Houillier P, Unwin R (2011). Does hypokalaemia cause nephropathy? An observational study of renal function in patients with Bartter or Gitelman syndrome.. QJM, 104(11), 939 - 944. doi:10.1093/qjmed/hcr095
Kesteloot H, Tzoulaki I, Brown IJ, Chan Q, Wijeyesekera A, Ueshima H, Zhao L, Dyer AR, Unwin RJ, Stamler J, Elliott P (2011). Relation of urinary calcium and magnesium excretion to blood pressure: The International Study Of Macro- And Micro-nutrients And Blood Pressure and The International Cooperative Study On Salt, Other Factors, And Blood Pressure.. Am J Epidemiol, 174(1), 44 - 51. doi:10.1093/aje/kwr049
Arulkumaran N, Unwin RJ, Tam FW (2011). A potential therapeutic role for P2X7 receptor (P2X7R) antagonists in the treatment of inflammatory diseases.. Expert Opin Investig Drugs, 20(7), 897 - 915. doi:10.1517/13543784.2011.578068
Crawford C, Kennedy-Lydon TM, Callaghan H, Sprott C, Simmons RL, Sawbridge L, Syme HM, Unwin RJ, Wildman SS, Peppiatt-Wildman CM (2011). Extracellular nucleotides affect pericyte-mediated regulation of rat in situ vasa recta diameter.. Acta Physiol (Oxf), 202(3), 241 - 251. doi:10.1111/j.1748-1716.2011.02310.x
Hoppe B, Groothoff JW, Hulton SA, Cochat P, Niaudet P, Kemper MJ, Deschênes G, Unwin R, Milliner D (2011). Efficacy and safety of Oxalobacter formigenes to reduce urinary oxalate in primary hyperoxaluria.. Nephrol Dial Transplant, 26(11), 3609 - 3615. doi:10.1093/ndt/gfr107
Furstenberg A, Walsh SB, Howie A, Jones G, Unwin RJ (2011). Calcineurin-Inhibitor Induced Hypertension, Hyperkalaemia and Metabolic Acidosis Is Caused by Overactivity of the Sodium Chloride Cotransporter..
Vargas-Poussou R, Dahan K, Kahila D, Venisse A, Riveira-Munoz E, Debaix H, Grisart B, Bridoux F, Unwin R, Moulin B, Haymann JP, Vantyghem MC, Rigothier C, Dussol B, Godin M, Nivet H, Dubourg L, Tack I, Gimenez-Roqueplo AP, Houillier P, Blanchard A, Devuyst O, Jeunemaitre X (2011). Spectrum of mutations in Gitelman syndrome.. J Am Soc Nephrol, 22(4), 693 - 703. doi:10.1681/ASN.2010090907
Unwin RJ, Luft FC, Shirley DG (2011). Pathophysiology and management of hypokalemia: a clinical perspective.. Nat Rev Nephrol, 7(2), 75 - 84. doi:10.1038/nrneph.2010.175
Hoorn EJ, Walsh SB, McCormick JA, Fürstenberg A, Yang CL, Roeschel T, Paliege A, Howie AJ, Conley J, Bachmann S, Unwin RJ, Ellison DH (2011). The calcineurin inhibitor tacrolimus activates the renal sodium chloride cotransporter to cause hypertension.. Nat Med, 17(10), 1304 - 1309. doi:10.1038/nm.2497

2010

Walsh SB, Unwin RJ (2010). Clinical hypokalemia and hyperkalemia at the bedside.. J Nephrol, 23 Suppl 16, S105 - S111.
Johri N, Jacquillet G, Unwin R (2010). Heavy metal poisoning: the effects of cadmium on the kidney.. Biometals, 23(5), 783 - 792. doi:10.1007/s10534-010-9328-y
Nikitorowitcz J, Aden N, Xu SW, Black C, Denton C, Unwin R, Abraham D, Stratton R (2010). Activation of stress induced signaling pathways in the epidermis in systemic sclerosis. CLIN EXP RHEUMATOL, 28(5), S72 - S72.
Srai SK, Chung B, Marks J, Pourvali K, Solanky N, Rapisarda C, Chaston TB, Hanif R, Unwin RJ, Debnam ES, Sharp PA (2010). Erythropoietin regulates intestinal iron absorption in a rat model of chronic renal failure.. Kidney Int, 78(7), 660 - 667. doi:10.1038/ki.2010.217
Marks J, Debnam ES, Unwin RJ (2010). Phosphate homeostasis and the renal-gastrointestinal axis.. Am J Physiol Renal Physiol, 299(2), F285 - F296. doi:10.1152/ajprenal.00508.2009
Chichger H, Marks J, Srai K, Debnam ES, Unwin RJ (2010). Modulation Of Renal Glucose Transport By Sweet Taste Sensing At The Proximal Tubule Brush Border Membrane. FASEB JOURNAL, 24, - .
Hall AM, Campanella M, Loesch A, Duchen MR, Unwin RJ (2010). Albumin uptake in OK cells exposed to rotenone: a model for studying the effects of mitochondrial dysfunction on endocytosis in the proximal tubule?. Nephron Physiol, 115(2), p9 - p19. doi:10.1159/000314540
Cesaro A, Brest P, Hofman V, Hébuterne X, Wildman S, Ferrua B, Marchetti S, Doglio A, Vouret-Craviari V, Galland F, Naquet P, Mograbi B, Unwin R, Hofman P (2010). Amplification loop of the inflammatory process is induced by P2X7R activation in intestinal epithelial cells in response to neutrophil transepithelial migration.. Am J Physiol Gastrointest Liver Physiol, 299(1), G32 - G42. doi:10.1152/ajpgi.00282.2009
Johri N, Cooper B, Robertson W, Choong S, Rickards D, Unwin R (2010). An Update and Practical Guide to Renal Stone Management. NEPHRON CLIN PRACT, 116(3), C159 - C171. doi:10.1159/000317196
Srai SK, Sharp PA, Marks J, Unwin RJ, Debnam ES (2010). The regulation of intestinal iron transport in a rat model of chronic renal failure. FASEB JOURNAL, 24, - .
Kennedy-Lydon TM, Crawford C, Sawbridge L, Unwin RJ, Wildman SSP, Peppiatt-Wildman CM (2010). Inhibition of medullary prostaglandin E2 (PGE2) by non-steroidal anti-inflammatory drugs (NSAIDs) adversely affects medullary blood flow. FASEB JOURNAL, 24, - .
Shirley DG, Faria NJ, Unwin RJ, Dobbie H (2010). Direct micropuncture evidence that matrix extracellular phosphoglycoprotein inhibits proximal tubular phosphate reabsorption.. Nephrol Dial Transplant, 25(10), 3191 - 3195. doi:10.1093/ndt/gfq263

2009

Unwin RJ, Shirley DG (2009). P2 purinoceptors and the kidney.. Purinergic Signal, 5(4), 431 - . doi:10.1007/s11302-009-9155-1
Hulton SA, Hoppe B, Milliner DS, Groothoff JW, Cochat P, Niaudet P, Kemper MJ, Deschenes G, Unwin R, Int Study Grp (2009). DOUBLE BLIND PLACEBO CONTROLLED TRIAL EVALUATING THE USE OF OXALOBACTER FORMIGENES (OXABACT (TM)) TREATMENT IN PRIMARY HYPEROXALURIA (PH). PEDIATR NEPHROL, 24(9), 1794 - 1794.
Bueter M, Ashrafian H, Frankel A, Tam F, Unwin R, Bloom S (2009). Upper Gastrointestinal Investigations Before Gastric Banding.
Bueter M, Ashrafian H, Frankel A, Tam F, Unwin R, Bloom S (2009). Energy Expenditure After Roux-En-Y Gastric Bypass in Rats.
Wildman SS, Boone M, Peppiatt-Wildman CM, Contreras-Sanz A, King BF, Shirley DG, Deen PM, Unwin RJ (2009). Nucleotides downregulate aquaporin 2 via activation of apical P2 receptors.. J Am Soc Nephrol, 20(7), 1480 - 1490. doi:10.1681/ASN.2008070686
Taylor SR, Turner CM, Elliott JI, McDaid J, Hewitt R, Smith J, Pickering MC, Whitehouse DL, Cook HT, Burnstock G, Pusey CD, Unwin RJ, Tam FW (2009). P2X7 deficiency attenuates renal injury in experimental glomerulonephritis.. J Am Soc Nephrol, 20(6), 1275 - 1281. doi:10.1681/ASN.2008060559
Peppiatt-Wildman CM, Crawford C, Desai TD, Unwin RJ (2009). Pericyte-mediated regulation of vasa recta capillaries in situ.. FASEB JOURNAL, 23, - .
Hall AM, Unwin RJ, Parker N, Duchen MR (2009). Multiphoton imaging reveals differences in mitochondrial function between nephron segments.. Journal of the American Society of Nephrology, 20(6), 1293 - 1302.
Bokenkamp A, Bockenhauer D, Cheong HI, Hoppe B, Tasic V, Unwin R, Ludwig M (2009). Dent-2 Disease: A Mild Variant of Lowe Syndrome. Journal of Pediatrics, 155(1), 94 - 99.
Shrimpton AE, Hoopes RR, Knohl SJ, Hueber P, Reed AA, Christie PT, Igarashi T, Lee P, Lehman A, White C, Milford DV, Sanchez MR, Unwin R, Wrong OM, Thakker RV, Scheinman SJ (2009). OCRL1 mutations in Dent 2 patients suggest a mechanism for phenotypic variability.. Nephron Physiol, 112(2), p27 - p36. doi:10.1159/000213506
Loesch A, Unwin R, Gandhi V, Burnstock G (2009). Sympathetic nerve varicosities in close apposition to basolateral membranes of collecting duct epithelial cells of rat kidney.. Nephron Physiol, 113(3), p15 - p21. doi:10.1159/000235246
Peppiatt-Wildman CM, Crawford C, Desai TD, Unwin RJ (2009). Pericyte-mediated regulation of vasa recta capillaries in situ.. FASEB JOURNAL, 23, - .
Kolman P, Pica A, Carvou N, Boyde A, Cockcroft S, Loesch A, Pizzey A, Simeoni M, Capasso G, Unwin RJ (2009). Insulin uptake across the luminal membrane of the rat proximal tubule in vivo and in vitro.. Am J Physiol Renal Physiol, 296(5), F1227 - F1237. doi:10.1152/ajprenal.90351.2008

2008

Vilasi A, Cutillas PR, Unwin RJ (2008). Application of proteomic techniques to the study of urine and renal tissue. PROTEOM CLIN APPL, 2(12), 1564 - 1574. doi:10.1002/prca.200800035
Nikali K, Vanegas JJ, Burley MW, Martinez J, Lopez LM, Bedoya G, Wrong OM, Povey S, Unwin RJ, Ruiz-Linares A (2008). Extensive founder effect for distal renal tubular acidosis (dRTA) with sensorineural deafness in an isolated South American population.. Am J Med Genet A, 146A(20), 2709 - 2712. doi:10.1002/ajmg.a.32495
Hall AM, Unwin RJ, Hanna MG, Duchen MR (2008). Renal function and mitochondrial cytopathy (MC): more questions than answers?. QJM, 101(10), 755 - 766. doi:10.1093/qjmed/hcn060
Norden AG, Gardner SC, Van't Hoff W, Unwin RJ (2008). Lysosomal enzymuria is a feature of hereditary Fanconi syndrome and is related to elevated CI-mannose-6-P-receptor excretion.. Nephrol Dial Transplant, 23(9), 2795 - 2803. doi:10.1093/ndt/gfm898
Walsh S, Borgese F, Gabillat N, Unwin R, Guizouarn H (2008). Cation transport activity of anion exchanger 1 mutations found in inherited distal renal tubular acidosis.. Am J Physiol Renal Physiol, 295(2), F343 - F350. doi:10.1152/ajprenal.00587.2007
Wildman S, Unwin R (2008). Luminal factors affecting apical P2 receptor mediated regulation of renal EnaC. PURINERG SIGNAL, 4, S102 - S102.
Marks J, Churchill LJ, Debnam ES, Unwin RJ (2008). Matrix Extracellular Phosphoglycoprotein Inhibits Phosphate Transport.. Journal of the American Society of Nephrology, 19, 2313 - 2320. doi:10.1681/ASN.2008030315
Dobbie H, Unwin RJ, Faria NJ, Shirley DG (2008). Matrix extracellular phosphoglycoprotein causes phosphaturia in rats by inhibiting tubular phosphate reabsorption.. Nephrol Dial Transplant, 23(2), 730 - 733. doi:10.1093/ndt/gfm535
Debnam ES, Marks J, Unwin RJ (2008). Glucose transport across the proximal tubule brush border membrane: response to diabetes mellitus.. Kidney Int, 73(3), 361 - 362. doi:10.1038/sj.ki.5002670
Anty R, Dahman M, Bekri S, Iannelli A, Gual P, Staccini-Myx A, Saint-Paul MC, Huet PM, Srai SKS, Unwin R, Le Marchand-Brustel Y, Gugenheim J, Tran A (2008). Low hepatic iron burden in morbidly obese women: A link with chronic inflammation.
Michell AR, Debnam ES, Unwin RJ (2008). Regulation of renal function by the gastrointestinal tract: potential role of gut-derived peptides and hormones. Annual Review of Physiology, 70, 379 - 403. doi:10.1146/annurev.physiol.69.040705.141330
Wildman SSP, Marks J, Turner CM, Yew-Booth L, Peppiatt-Wildman CM, King BF, Shirley DG, Wang W, Unwin RJ (2008). Sodium-dependent regulation of renal amiloride sensitive currents by apical P2 receptors.. Journal of The American Society of Nephrology, 19, 731 - 742. doi:10.1681/ASN.2007040443
Wildman SS, Shirley DG, King BF, Unwin RJ (2008). Sodium dependent regulation of ENaC by apical P2 receptors in rat collecting duct: are P2X receptors luminal sodium sensors?.
Anty R, Dahman M, Iannelli A, Gual P, Staccini-Myx A, Amor IB, Luciani N, Saint-Paul MC, Huet PM, Sadoul JL, Srai S K U, R G, J LM-B, Y T, A B, S (2008). Bariatric surgery can correct iron depletion in morbidly obese women: a link with chronic inflammation.. Obesity Surgery, 18(6), 709 - 714. doi:10.1007/s11695-007-9276-y

2007

Turner CM, King BF, Srai KS, Unwin RJ (2007). Antagonism of endogenous putative P2Y receptors reduces the growth of MDCK-derived cysts cultured in vitro.. American Journal of Physiology, 292, F15 - F25.
Capasso G, Debnam ES, Cutillas P, Brunskill NJ, Unwin RJ (2007). Classical and novel hormonal influences on renal tubular transport and the emerging concept of intracrine regulation. In Seldin DW, Giebisch G (Ed.), The Kidney: Physiology and Pathophysiology (pp. 979 - 1003). : Lippincott, Williams & Wilkins.
Walsh SB, Turner CM, Toye A, Wagner C, Jaeger P, Laing C, Unwin R (2007). Immunohistochemical comparison of a case of inherited distal renal tubular acidosis (with a unique AE1 mutation) with an acquired case secondary to autoimmune disease.. Nephrology Dialysis Transplantation, 22(3), 807 - 812.
Hall AM, Unwin RJ (2007). The not so 'mighty chondrion': emergence of renal diseases due to mitochondrial dysfunction.. Nephron Physiol, 105(1), p1 - 10. doi:10.1159/000096860
Shirley DG, Walsh SB, Wrong OM, Unwin RJ (2007). Response to 'Simultaneous fludrocortisone and furosemide for assessment of urinary acidification'. KIDNEY INT, 72(9), 1164 - 1164. doi:10.1038/sj.ki.5002535
Goestemeyer AK, Marks J, Srai SK, Debnam ES, Unwin RJ (2007). GLUT2 protein at the rat proximal tubule brush border membrane correlates with protein kinase C (PKC)-betal and plasma glucose concentration.. Diabetologia, 50(10), 2209 - 2217. doi:10.1007/s00125-007-0778-x
Carvou N, Norden AG, Unwin RJ, Cockcroft S (2007). Signalling through phospholipase C interferes with clathrin-mediated endocytosis. Cellular Signalling, 19(1), 42 - 51.
Marks J, Churchill LJ, Srai SK, Biber J, Murer H, Jaeger P, Debnam ES, Unwin RJ (2007). Intestinal phosphate absorption in a model of chronic renal failure.. Kidney International, 72(2), 166 - 173. doi:10.1038/sj.ki.5002292
Wildman SSP, Turner CM, Marks J, Shirley DG, King BF, Unwin RJ (2007). Differential regulation of renal ENaC by apical P2X and P2Y receptors.
Norden AG, Rodriguez-Cutillas P, Unwin RJ (2007). Clinical urinary peptidomics: learning to walk before we can run.. Clin Chem, 53(3), 375 - 376. doi:10.1373/clinchem.2006.084038
Walsh S, Turner CM, Toye A, Wagner C, Jaeger P, Laing C, Unwin R (2007). Immunohistochemical comparison of a case of inherited distal renal tubular acidosis (with a unique AE1 mutation) with an acquired case secondary to autoimmune disease. NEPHROL DIAL TRANSPL, 22(3), 807 - 812. doi:10.1093/ndt/gf1662
Turner CM, Tam FWK, Lai P-C, Tarzi RM, Burnstock G, Pusey CD, Cook HT, Unwin RJ (2007). Increased expression of the pro-apoptotic ATP-sensitive P2X7 receptor in experimental and human glomerulonephritis. Nephrology Dialysis Transplantation, 22(2), 386 - 395.
Walsh SB, Shirley DG, Wrong OM, Unwin RJ (2007). Urinary acidification assessed by simultaneous furosemide and fludrocortisone treatment: an alternative to ammonium chloride.. Kidney International, 71(12), 1310 - 1316.
Vilasi A, Cutillas PR, Maher AD, Zirah SF, Capasso G, Norden AW, Holmes E, Nicholson JK, Unwin RJ (2007). Combined proteomic and metabonomic studies in three genetic forms of the renal Fanconi syndrome.. Am J Physiol Renal Physiol, 293(2), F456 - F467. doi:10.1152/ajprenal.00095.2007

2006

Kolman P, Pica A, Boyde A, Unwin RJ (2006). Real-time in vivo quantitative fluorescence measurements in rat kidney physiology. J ANAT, 209(3), 417 - 417.
Vekaria RM, Unwin R J S, D G (2006). Intraluminal ATP concentrations in rat renal tubules.. Journal of the American Society of Nephrology, 17(7), 1841 - 1847. doi:10.1681/ASN.2005111171
Laing CM, Roberts R, Summers S, Friedland JS, Lighstone L, Unwin RJ (2006). Distal renal tubular acidosis in association with HIV infection and AIDS (vol 21, pg 1420, 2006). NEPHROL DIAL TRANSPL, 21(7), 2044 - 2044. doi:10.1093/ndt/gfl377
Robertson W, Choong S, Jaeger P, Unwin R (2006). The relationship between calculated and measured urinary pH in patients with urolithiasis.
Laing CM, Roberts R, Summers S, Friedland JS, Lighstone L, Unwin RJ (2006). Distal renal tubular acidosis in association with HIV infection and AIDS.. Nephrology Dialysis Transplantation, 21(5), 1420 - 1422.
Unwin RJ, Capasso G (2006). Bartter's and Gitelman's syndromes: their relationship to the actions of loop and thiazide diuretics.. Current Opinion in Pharmacology, 6(2), 208 - 213.
Wildman SS, Boone M, Peppiatt CM, Churchill LJ, Shirley DG, King BF, Deen PMT, Unwin RJ (2006). Immunofluorescent labelling reveals dDAVP-dependent P2 receptor expression and apical P2 receptor-mediated inhibition of AQP2 expression in mpkCCD(cl4) cultures..
Vekaria RM, Shirley DG, Sevigny J, Unwin RJ (2006). Immunolocalization of ectonucleotidases along the rat nephron.. American Journal of Physiology - Renal Physiology, 290(2), F550 - F560.
Bailey MA, Shirley DG, King BF, Burnstock G, Unwin RJ (2006). Extracellular nucleotides and renal function. In Alpern RJ, Hebert SC (Ed.), Seldin and Giebisch's The Kidney (pp. 477 - 496). : Elsevier.
Marks J, Srai SK, Biber J, Murer H, Unwin RJ, Debnam ES (2006). Intestinal phosphate absorption and the effect of Vitamin D: a comparison of rat with mouse. Experimental Physiology, 91(3), 531 - 537.
Wildman SS, Turner CM, Marks J, Peppiatt CM, Churchill LJ, Li D, Shirley DG, Wang W, King BF, Unwin RJ (2006). Evidence for P2X receptor-mediated inhibition of sodium reabsorption in collecting ducts from sodium-restricted rats..
Wildman SS, Peppiatt CM, Boone M, Konings I, Marks J, Churchill LJ, Turner CM, Shirley DG, King BF, Deen PMT, Unwin RJ (2006). Possible role of apical P2 receptors in modulating aquaporin-2-mediatiated water reabsorption in the collecting duct..
Chapman E, Hussain S, Peppiatt CM, Marks J, Churchill LJ, Turner CM, King BF, Unwin RJ, Wildman SS (2006). Immunohistochemical localisation of P2 receptors in the rat renal collecting duct:effects of altering dietary sodium intake..
Laing CM, Unwin RJ (2006). Renal tubular acidosis.. J Nephrol, 19 Suppl 9, S46 - S52.

2005

Neild GH, Thakker RV, Unwin RJ, Wrong OM (2005). Dent's disease.. Nephrology Dialysis Transplantation, 20(10), 2284 - 2285.
Laing CM, Toye AM, Capasso G, Unwin RJ (2005). Renal tubular acidosis: developments in our understanding of the molecular basis.. The International Journal of Biochemistry and Cell Biology, 37(6), 1151 - 1161.
Shirley DG, Bailey MA, Unwin RJ (2005). In vivo stimulation of apical P2 receptors in collecting ducts: evidence for inhibition of sodium reabsorption.. American Journal of Physiology - Renal Physiology, 288(6), F1243 - F1248.
Vekaria RM, Unwin RJ, Shirley DG (2005). Is adenosine 5 '-triphosphate secreted into the proximal tubular lumen?.
Hillman KA, Burnstock G, Unwin R (2005). The P2X₇ ATP receptor in the kidney: a matter of life or death?. Nephron Experimental Nephrology, 101, E24 - E30.
Cutillas PR, Biber J, Marks J, Jacob R, Steiger B, Cramer R, Waterfield MD, Burlingame AL, Unwin RJ (2005). Proteomics analysis of plasma membrane vesicles isolated from the rat renal cortex. Proteomics, 5(1), 101 - 112.
Capasso G, Jaeger P, Robertson WG, Unwin RJ (2005). Uric acid and the kidney: urate transport, stone disease and progressive renal failure.. Current Pharmaceutical Design, 11(32), 4153 - 4159.
Wildman SS, Marks J, Churchill LJ, Peppiatt CM, Horisburger JD, King BF, Unwin RJ (2005). Molecular cross-talk between epithelial sodium channels and ATP-gated P2X receptors.
Wildman SS, Marks J, Churchill LJ, Peppiatt CM, Chraibi A, Shirley DG, Horisberger JD, King BF, Unwin RJ (2005). Regulatory interdependence of cloned epithelial Na+ channels and P2X receptors.. Journal of the American Society of Nephrology, Sep;16(9), 2586 - 2597.
Faria NJ, Dobbie H, Slater JM, Shirley DG, Stocking CJ, Unwin RJ (2005). Simultaneous determination of anions in nanoliter volumes.. Kidney International, 67(1), 357 - 363.
Wildman SS, Marks J, Churchill LJ, Peppiatt CM, Horisberger J-D, King BF, Unwin RJ (2005). Molecular interactions between cloned epithelial sodium channels and ATP-gated P2X receptors..
Unwin RJ, Capasso G, Robertson WG, Choong S (2005). A guide to renal stone disease.. Practitioner, 249(1666), 18 - passim.
Bekri S, Enica A, Ghafari T, Plaza G, Champenois I, Choukroun G, Unwin R, Jaeger P (2005). Fabry disease in patients with end-stage renal failure: the potential benefits of screening.. Nephron Clin Pract, 101(1), c33 - c38. doi:10.1159/000085709

2004

Hillman KA, Woolf AS, Johnson TM, Wade A, Unwin RJ, Winyard PJ (2004). The P2X7 ATP receptor modulates renal cyst development in vitro. Biochemical and Biophysical Research Communications, 322(2), 434 - 439.
Wildman SS, Shirley DG, King BF, Unwin RJ (2004). Potential regulation of Na+ reabsorption in Na+-restricted rats by an ATP-gated P2X4/6 receptor:pharmacological evidence..
Simeoni M, Boyde A, Shirley DG, Capasso G, Unwin RJ (2004). Application of red laser video-rate scanning confocal microscopy to in vivo assessment of tubular function in the rat: selective action of diuretics on tubular diameter.. Experimental Physiology, 89(2), 181 - 185.
Wildman SS, Shirley DG, King BF, Unwin RJ (2004). Indirect evidence for regulation of sodium reabsorption in sodium-restricted rats by an ATP-gated heteromeric P2X receptor..
Cutillas PR, Norden AG, Cramer R, Burlingame AL, Unwin RJ (2004). Urinary proteomics of renal Fanconi syndrome.. Contributions to Nephrology, 141, 155 - 169.
Turner CM, Tam FWK, Lai PC, Tarzi RM, Burnstock G, Pusey CD, Cook HT, Unwin R (2004). Glomerular expression of the ATP-sensitive P2X₇ receptor is increased in proliferative glomerulonephritis.
Bailey MA, Turner CM, Hus-Citharel A, Marchetti J, Imbert-Teboul M, Milner P, Burnstock G, Unwin RJ (2004). P2Y receptors present in the native and isolated rat glomerulus.. Nephron Physiology, 96(3), p79 - p90.
Turner CM, Ramesh B, Srai SK, Burnstock G, Unwin RJ (2004). Altered ATP-sensitive P2 receptor subtype expression in the Han:SPRD cy/+ rat, a model of autosomal dominant polycystic kidney disease.. Cells Tissues Organs, 178(3), 168 - 179.
Unwin RJ, Capasso G, Shirley DG (2004). An overview of divalent cation and citrate handling by the kidney.. Nephron Physiology, 98(2), p15 - p20.
Vonend O, Turner CM, Chan CM, Loesch A, Dell'Anna GC, Srai KS, Burnstock G, Unwin RJ (2004). Glomerular expression of the ATP-sensitive P2X receptor in diabetic and hypertensive rat models.. Kidney International, 66(1), 157 - 166.
Cutillas PR, Chalkley RJ, Hansen KC, Cramer R, Norden AG, Waterfield MD, Burlingame AL, Unwin RJ (2004). The urinary proteome in Fanconi syndrome implies specificity in the reabsorption of proteins by renal proximal tubule cells.. American Journal of Physiology - Renal Physiology, 287(3), F353 - F364.
Cutillas PR, Norden AGW, Cramer R, Burlingame AL, Unwin RJ (2004). Urinary proteomics of renal Fanconi syndrome. In Thongboonkerd V, Klein JB (Ed.), Vol. 141: Proteomics in Nephrology (pp. 142 - 154). : Karger.
Norden AGW, Sharratt P, Cutillas PR, Cramer R, Gardner SC, Unwin RJ (2004). Quantitative amino acid and proteomic analysis: very low excretion of polypeptides >750Da in normal urine. Kidney International, 66(5), 1994 - 2004.
Cutillas PR, Chalkley RJ, Hansen KC, Cramer R, Norden AGW, Waterfield MD, Burlingame AL, Unwin RJ (2004). The urinary proteome in the Fanconi syndrome implies specificity in the reabsorption of proteins by renal proximal tubule cells. American Journal of Physiology - Renal Physiology, 287(3), F353 - F364.
Cutillas PR, Biber J, Marks J, Jacob R, Steiger B, Cramer R, Waterfield M, Burlingame AL, Unwin RJ (2004). Proteomic analysis of plasma membrane vesicles isolated from the rat renal cortex. Proteomics, 5, 101 - 112.
Cutillas PR, Norden AG, Cramer R, Burlingame AL, Unwin RJ (2004). Urinary proteomics in Fanconi Syndrome. In Thonboonkerd V, Klein JB (Ed.), Proteomics in Nephrology, Contributions to Nephrology (pp. 155 - 169). : Karger.
Albano L, Champenois I, Cassuto-Vignier E, Gigante M, Amiel J, Unwin RJ, Robertson WG, Jaeger PH (2004). Nephrolithiasis in kidney transplant patients (KTP): the chicken and egg story revisited. In Gohel MDI, Au DWT (Ed.), Kidney Stones: Inside or Out (pp. 207 - 208). : Hong Kong Polytechnic University Press.
Robertson WG, Champenois I, Unwin RJ, Amiel J, Jaeger PH (2004). Diet and renal leaks in the pathogenesis of calcium nephrolithiasis - an integrated model. In Gohel MDI, Au DWT (Ed.), Kidney Stones: Inside or Out (pp. 346 - 348). : Hong Kong Polytechnic University Press.
Robertson WG, Jaeger PH, Unwin RJ (2004). Invited editors of special issue on Urolithiasis. Nephron, 98(2), - .
Cutillas P, Burlingame A, Unwin R (2004). Proteomic strategies and their application in studies of renal function.. News in Physiological Sciences, 19, 114 - 119.

2003

Cutillas PR, Norden AG, Cramer R, Burlingame AL, Unwin RJ (2003). Detection and analysis of urinary peptides by on-line liquid chromatography and mass spectrometry: application to patients with renal Fanconi syndrome.. Clinical Science, 104(5), 483 - 490.
Miller RF, Shahmonesh M, Hanna MG, Unwin RJ, Schapira AH, Weller IV (2003). Polyphenotypic expression of mitochondrial toxicity caused by nucleoside reverse transcriptase inhibitors.. Antiviral Therapy, 8(3), 253 - 257.
Hooper KM, Unwin RJ, Sutters M (2003). The isolated C-terminus of polycystin-1 promotes increased ATP-stimulated chloride secretion in a collecting duct cell line.. Clinical Science, 104(3), 217 - 221.
Marks J, Debnam ES, Dashwood MR, Srai SK, Unwin RJ (2003). Detection of glucagon receptor mRNA in the rat proximal tubule: potential role for glucagon in the control of renal glucose transport.. Clin Sci (Lond), 104(3), 253 - 258. doi:10.1042/CS20020336
Marks J, Debnam ES, Dashwood MR, Srai SK, Unwin RJ (2003). Detection of glucagon receptor mRNA in the rat proximal tubule: potential role for glucagon in the control of renal glucose transport.. Clinical Science, 104, 253 - 258.
Marks J, Debnam ES, Churchill L, Srai SK, Unwin RJ (2003). GLUT2 protein is translocated to the rat proximal tubule BBM in response to diabetic hyperglycemia.
Wildman SS, Unwin RJ, King BF (2003). Extended pharmacological profiles of rat P2Y₂ and rat P2Y₄ receptors and their sensitivity to extracellular H⁺ and Zn²⁺ ions.. British Journal of Pharmacology, 140(7), 1177 - 1186.
Wildman SS, Hooper KM, Turner CM, Sham JS, Lakatta EG, King BF, Unwin RJ, Sutters M (2003). The isolated polycystin-1 cytoplasmic COOH terminus prolongs ATP-stimulated Cl- conductance through increased Ca2+ entry.. American Journal of Physiology - Renal Physiology, 285, F1168 - F1178.
Blaikley JF, Sutton P, Walters M, Lapsley M, Norden A, Pugsley W, Unwin R (2003). Tubular proteinuria and enzymuria following open heart surgery. Intensive Care Medicine, 8, 1364 - 1367.
Wildman SS, King BF, Unwin RJ (2003). Recharacterisation of UTP-sensitive P2Y receptors found in rat kidney.
Wildman SS, Chraibi A, Horisberger J-D, King BF, Unwin RJ (2003). Downstream regulation of ENaC by ATP-gated P2X receptors.
Wildman SS, Chraibi A, Horisberger J-D, King BF, Unwin RJ (2003). Does ENaC regulate membrane trafficking of other ion-channels?.
Sutters M, Wildman SS, Hooper KM, Turner CM, Sham J, Lakatta EG, King BF, Unwin RJ (2003). The isolated cytoplasmic C-terminus of polycystin-1 prolongs ATP-stimulated chloride conductance through agonist simulated calcium entry.
Turner CM, Vonend O, Chan C, Burnstock G, Unwin RJ (2003). The pattern of distribution of selected ATP-sensitive P2 receptor subtypes in normal rat kidney: an immunohistological study.. Cells Tissues Organs, 175(2), 105 - 117.
Marks J, Carvou N, Debnam E, Srai SKS, Unwin RJ (2003). Diabetes increases facilitative glucose uptake and GLUT 2 expression at the proximal tubule brush border membrane. The Journal of Physiology, 553, 137 - 145.
Shirley DG, Capasso G, Bailey M, Unwin RJ (2003). Fundamentals of Renal Physiology. In Glynne P, Allen A, Pusey C (Ed.), Acute renal failure in practice (pp. 3 - 36). : Imperial College Press.
Unwin RJ, Capasso G, Robertson WG (2003). Urinary stones, nephrocalcinosis and renal tubular acidosis. In Warrell DA, Cox TM, Firth JD, Benz Jr EJ (Ed.), The Oxford Textbook of Medicine (pp. 434 - 446). : Oxford University Press.
Dobbie H, Capasso G, Unwin R (2003). Diuretics and ß-blockers. In Wilcox C, Brady H (Ed.), Therapy in Nephrology and Hypertension. A companion to Brenner and Rector's The Kidney (pp. 537 - 545). : W.B.Saunders Company.
Capasso G, Unwin RJ (2003). La syndrome di Fanconi. In De Santo NG, Camussi G, D'Armiento M (Ed.), Malattie Dell' Apparato Urinario (pp. 149 - 154). : Editoriale Bios..
Unwin RJ, Bailey MA, Burnstock G (2003). Purinergic signaling along the renal tubule: the current state of play. News in Physiological Sciences, 18, 237 - 241.
Leipziger J, Bailey MA, Unwin RJ (2003). Purinergic receptors in the kidney. In Schwiebert EM (Ed.), Purinergic Receptors and Signaling (Current Topics in Membranes 54) (pp. 369 - 394). : Academic Press.
Shirley DG, Capasso G, Unwin RJ (2003). Renal Physiology. In Johnson R, Feehally J (Ed.), Principles of Clinical Nephrology (pp. 2.1 - 2.11). : J. Mosby International.
Unwin RJ, Capasso G (2003). Acid-base and electrolytes: common fluid and electrolyte disorders. Medicine, 31(5), 11 - 17.
Cutillas PR, Marks J, Cramer R, Unwin RJ (2003). Proteomic analysis of renal cortical brush border membrane preparations: towards characterizing the proximal tubular cell apical membrane proteome.
Turner CM, Srai KS, Unwin RJ (2003). The effect of modulators of ATP-sensitive P2 receptors on MDCK-derived cysts in vitro.
Turner CM, Srai KS, Unwin RJ (2003). Altered kidney expression of ATP-sensitive P2 receptor subtype mRNA in a rat model of autosomal dominant polycystic kidney disease, the Han:SPRD rat.
Turner CM, Srai SKS, Unwin RJ (2003). The effect of P2 receptor inhibition on cultured MDCK cysts in vitro.
Pica A, Unwin RJ, Capasso G (2003). Acidosi tubulare renale. In De Santo NG, Camussi G, D'Armiento M (Ed.), Malattie Dell' Apparato Urinario (pp. 121 - 126). : Editoriale Bios..
Wildman SS, Unwin RJ, King BF (2003). Extended pharmacological profiles of rat P2Y2 and rat P2Y4 receptors and their sensitivity to extracellular H+ and Zn2+ ions.. Br J Pharmacol, 140(7), 1177 - 1186. doi:10.1038/sj.bjp.0705544
Marks J, Carvou NJ, Debnam ES, Srai SK, Unwin RJ (2003). Diabetes increases facilitative glucose uptake and GLUT2 expression at the rat proximal tubule brush border membrane.. The Journal of Physiology, 553(1), 137 - 145. doi:10.1113/jphysiol.2003.046268
Wildman SS, Chraibi A, Horisberger JD, King BF, Unwin RJ (2003). Downstream regulation of ENaC by ATP-gated P2X receptors.
Wildman SS, Chraibi A, Horisberger JD, King BF, Unwin RJ (2003). Does ENaC regulate membrane trafficking of other ion-channels?.
Norden AGW, Sharratt P, Cutillas PR, O'Driscoll E, Gardner SC, Unwin RJ (2003). Quantitative amino acid and proteomic analysis of normal and Fanconi urine: No evidence for significant excretion of plasma protein fragments in normal urine.
Carvou NJC, Unwin R, Cockcroft S (2003). Insulin and beta 2-glycoprotein I are endocytosed via different pathways in the kidney proximal tubule.
Cutillas PR, Marks J, Cramer R, Burlingame AL, Unwin RJ (2003). Protcomic analysis of the renal cortical brush border membrane preparation: Towards characterizing the proximal tubular cell apical membrane proteome.
Dobbie H, Shirley DG, Faria NJ, Rowe PS, Slater JM, Unwin RJ (2003). Infusion of the Bone-Derived protein MEPE causes phosphaturia in rats..
Shirley DG, Vekaria RM, Unwin RJ (2003). Proximal and distal tubular fluid ATP concentrations in vivo..
Wildman SS, King BF, Unwin RJ (2003). Recharacterisation of UTP-sensitive P2V receptors found in rat kidney..
Vekaria RM, Shirley DG, Unwin RJ (2003). Immunolocalisation of ectonucleotidases in the renal tubule..
Sutters M, Wildman SS, Hooper KM, Turner CM, Sham JSK, Lakatta EG, King BF, Unwin RJ (2003). The isolated cystoplasmic C-terminus of polycystin-1 prolongs ATP-Stimulated chloride conductance through increased agonist stimulated calcium entry..
Turner CM, Srai KS, Unwin RJ (2003). The effect of modulators of ATP-Sensitive P2 receptors on MDCK-Derived cysts cultured In Vitro..
Hillman KA, Unwin RJ, Woolf AS, Winyard PJ (2003). P2X7 signalling is a modifier of epithelial lumen formation..
Turner CM, Srai KS, Unwin RJ (2003). Altered kidney expression of ATP-Sensitive p2 receptor subtype mRNA in a rat model of autosomal dominant polycystic kidney disease, the Han : SPRD rat..
Cutillas PR, Chalkley R, Hansen K, Cramer R, Norden AWG, Burlingame AL, Unwin RJ (2003). Probing the specificity of the megalin-mediated endocytic pathway by proteomics..
Albano L, Casez JP, Cassuto-Viguier E, Saussac S, Unwin R, Jaeger P (2003). Effect of tacrolimus versus cyclosporine a on bone metabolism after kidney transplantation: A cross-section study in 28 patients..
Hillman KA, Harada H, Chan CM, Townsend-Nicholson A, Moss SE, Miyamoto K, Suketa Y, Burnstock G, Unwin RJ, Dunn PM (2003). Chicken DT40 cells stably transfected with the rat P2X7 receptor ion channel: a system suitable for the study of purine receptor-mediated cell death. Biochemical Pharmacology, 66(3), 415 - 424.
Bailey MA, Haton C, Orea V, Sassard J, Bailly C, Unwin RJ, Imbert-Teboul M (2003). ETA receptor-mediated Ca²⁺ signaling in thin descending limbs of Henle's loop: impairment in genetic hypertension.. Kidney International, 63(4), 1276 - 1284.

2002

Wildman SS, Brown SG, Rahman M, Noel CA, Churchill L, Burnstock G, Unwin RJ, King BF (2002). Sensitization by extracellular Ca⁽²⁺⁾ of rat P2X₅ receptor and its pharmacological properties compared with rat P2X₁.. Molecular Pharmacology, 62(4), 957 - 966. doi:10.1124/mol.62.4.957
Hillman KA, Johnson TM, Winyard PJ, Burnstock G, Unwin RJ, Woolf AS (2002). P2X(7) receptors are expressed during mouse nephrogenesis and in collecting duct cysts of the cpk/cpk mouse. Experimental Nephrology, 10(1), 34 - 42.
Cutillas PR, Norden AGW, Cramer R, Burlingame AL, Unwin RJ (2002). Proteomic analysis of renal Fanconi urine.. J AM SOC NEPHROL, 13, 80A - 80A.
Hooper KM, Unwin RJ, Sutters M (2002). Expression of the isolated C terminus of polycystin-1 augments ATP stimulated chloride secretion.. J AM SOC NEPHROL, 13, 107A - 107A.
Hillman KA, Johnson TM, Unwin RJ, Woolf AS, Winyard PJ (2002). The P2X7 ATP receptor modulates renal cyst morphogenesis.. J AM SOC NEPHROL, 13, 115A - 115A.
Marks J, Debnam ES, Churchill L, Srai SK, Unwin RJ (2002). Diabetic hyperglycemia causes the expression of GLUT2 at the proximal tubule brush border membrane..
Norden AG, Lapsley M, Lee PJ, Pusey CD, Scheinman SJ, Tam FW, Thakker RV, Unwin RJ, Wrong O (2002). Fragmentation of filtered proteins and implications for glomerular protein sieving in Fanconi syndrome. Kidney International, 62(1), 349 - .
Unwin RJ, Shirley DG, Capasso G (2002). Urinary acidification and distal renal tubular acidosis. Journal of Nephrology, 15(S5), S142 - S150.
Toye AM, Bruce LJ, Unwin RJ, Wrong O, Tanner MJ (2002). Band 3 Walton, a C-terminal deletion associated with distal renal tubular acidosis, is expressed in the red cell membrane but retained internally in kidney cells. Blood, 99(1), 342 - 347.
Turner C, Vonend O, Burnstock G, Unwin R (2002). P2 nucleotide receptor distribution in isolated normal rat kidney.
Capasso G, Unwin R, Rizzo M, Pica A, Giebisch G (2002). Bicarbonate transport along the loop of Henle: molecular mechanisms and regulation. Journal of Nephrology, 15(suppl.), S88 - S96.
Dobbie H, Lanham J, Unwin R (2002). Morphea presenting as widespread oedema. Journal of the Royal Society of Medicine, 95(9), 459 - 460.
Marks J, Debnam ES, Churchill L, Srai SK, Unwin RJ (2002). Diabetic hyperglycaemia causes the expression of GLUT2 at the proximal tubule brush border membrane.
Wildman SS, Brown SG, Rahman M, Burnstock G, Unwin R, King B (2002). The rP2X5 receptor is pharmacologically similar to the rP2X1 receptor, but operationally different..
Wrong O, Bruce LJ, Unwin RJ, Toye AM, Tanner MJA (2002). Band 3 mutations, distal renal tubular acidosis, and Southeast Asian ovalocytosis. Kidney International, 62(1), 10 - 19.
Capasso G, Unwin RJ, Pica A, Quagliuolo L, Giovane A (2002). Iothalamate measured by capillary electrophoresis is a suitable alternative to radiolabeled inulin in renal micropuncture. Kidney International, 62(3), 1068 - 1074.
Hillman KA, Johnson TM, Winyard PJD, Burnstock G, Unwin RJ, Woolf AS (2002). P2X7, an extracellular ATP receptor, is expressed site-specifically through mouse nephrogenesis and in cpk/cpk kidney collecting duct cysts. Experimental Nephrology, 10, 34 - 42.
Marks J, Dehnam ES, Norgate D, Srai SKS, Unwin RJ (2002). Differential effect of streptozotocin diabetes on expression of glucagon receptor (GR) and glucagon-like peptide-1 receptor (GLP-1R) mRNA in isolated defined rat nephron segments.
Norden AG, Lapsley M, Igarashi T, Kelleher CL, Lee PJ, Matsuyama T, Scheinman SJ, Shiraga H, Sundin DP, Thakker RV, Unwin RJ, Verroust PJ, Moestrup SK (2002). Urinary megalin deficiency implicates abnormal tubular endocytic megalin function in Fanconi syndrome. Journal of the American Society of Nephrology, 13, 125 - 133.
Norden AG, Lapsley M, Igarashi T, Kelleher CL, Lee PJ, Matsuyama T, Scheinman SJ, Shiraga H, Sundin DP, Thakker RV, Unwin RJ, Verroust P, Moestrup SK (2002). Urinary megalin deficiency implicates abnormal tubular endocytic function in Fanconi syndrome. Journal of the American Society of Nephrology, 13(1), 125 - 133.
Shirley DG, Capasso G, Unwin RJ (2002). Renal haemodynamics and glomerular filtration. In Glynne PA, Allen AR, Pusey CD (Ed.), Acute renal failure in practice (pp. - ). : Imperial College Press.
Shirley DG, Capasso G, Bailey MA, Unwin RJ (2002). Renal tubular function. In Glynne PA, Allen AR, Pusey CD (Ed.), Acute renal failure in practice (pp. - ). : Imperial College Press.
Turner CM, Vonend O, Burnstock G, Unwin RJ (2002). P2 nucleotide receptor distribution in isolated normal rat kidney. The Journal of Physiology, 539P, 138P - .
Unwin RJ, Shirley DG, Capasso G (2002). Urinary acidification and distal renal tubular acidosis. Journal of Nephrology, 15(Suppl.), S142 - S150.
Unwin RJ, Shirley DG, Capasso G (2002). Urinary acidification and distal renal tubular acidosis. Journal of Nephrology, 15(5), S142 - S150.
Wildman SS, Turner C, Burnstock G, Unwin R, King B (2002). P2Y4 receptor abundance in rat kidney epithelial cysts and its properties in vitro..
Wildman SS, Brown SG, Rahman M, Noel CA, Churchill L, Burnstock G, Unwin RJ, King BF (2002). Sensitization by extracellular Ca(2+) of rat P2X(5) receptor and its pharmacological properties compared with rat P2X(1).. Mol Pharmacol, 62(4), 957 - 966.

2001

Bailey MA, Unwin RJ, Shirley DG (2001). In vivo inhibition of renal 11β-hydroxysteroid dehydrogenase in the rat stimulates collecting duct sodium reabsorption. Clinical Science, 101(2), 195 - 198.
Norden AG, Lapsley M, Lee PJ, Pusey CD, Scheinman SJ, Tam FW, Thakker RV, Unwin RJ, Wrong O (2001). Glomerular protein sieving and implications for renal failure in Fanconi syndrome. Kidney International, 60(5), 1885 - 1892.
Vonend O, Turner C, Loesch A, Srai K, Burnstock G, Unwin R (2001). P2X7 receptor expression in diabetic nephropathy.
Unwin RJ, Capasso G (2001). The renal tubular acidoses. Journal of the Royal Society of Medicine, 94(5), 221 - 225.
Simeoni M, Shirley DG, Boyde A, Capasso G, Unwin R (2001). Application of video-rate scanning confocal microscopy in vivo: selective effects of diuretics on renal tubular diameter.
Bailey MA, Imbert-Teboul M, Turner C, Marsy S, Srai SKS, Burnstock G, Unwin RJ (2001). Axial distribution and characterisation of basolateral P2Y receptors along renal tubule. Kidney International, 58, 1893 - 1901.
Biller KJ, Unwin RJ, Shirley DG (2001). Distal tubular electrolyte transport during inhibition of renal 11 beta-hydroxysteroid dehydrogenase. American Journal of Physiology - Renal Physiology, 280(1), F172 - F179.
Baigent SA, Unwin R, Yeng CC (2001). Mathematical modelling of profiled haemodialysis: a simplified approach. Journal of Theoretical Medicine, 3(2), 143 - 160. doi:10.1080/10273660108833070
Capasso G, Debnam ES, Unwin RJ (2001). Hormonal influences on renal tubule transport: Glucagon, Somatostatin, Insulin, Glucocorticoid and Thyroid Hormones, Catecholamines and selected gut-renal peptides. In Seldin DW, Giebisch G (Ed.), The Kidney: Physiology and Pathophysiology (pp. 1411 - 1439). : Lippincott, Williams and Wilkins.
Norden AGW, Lapsley M, Lee PJ, Pusey CD, Scheinman SJ, Tam FWK, Thakker RV, Unwin RJ, Verroust PJ, Wrong O (2001). Proteinuria of the Fanconi syndrome comprises proteins in the mass range from insulin to IgG. Kidney International, 60, 1885 - 1892.
Wilon F, Disse-Nicodeme S, choate K, Ishikawa K, Nelson-Willians C, Desitter I, Unwin RJ, Gunal M, Milford D, Lipkin G, Achard JM, Feely M, Dussol B, Berland Y, Simon D, Farfel Z, Jeunemaitre X, Lifton R (2001). Mutations in WNK kinases reveal a novel mechanism of human hypertension. Science, 293, 1107 - 1112.
Bailey MA, Unwin RJ, Shirley DG (2001). In vivo inhibition of renal 11 beta-hydroxysteroid dehydrogenase in the rat stimulates collecting duct sodium reabsorption. Clinical Science, 101, 195 - 198.
Wilson FH, Disse-Nicodème S, Choate KA, Ishikawa K, Nelson-Williams C, Desitter I, Gunel M, Milford DV, Lipkin GW, Achard JM, Feely MP, Dussol B, Berland Y, Unwin RJ, Mayan H, Simon DB, Farfel Z, Jeunemaitre X, Lifton RP (2001). Human hypertension caused by mutations in WNK kinases. Science, 293(5532), 1107 - 1112. doi:10.1126/science.1062844
Bailey MA, Imbert-Teboul M, Turner C, Srai SK, Burnstock G, Unwin RJ (2001). Evidence for basolateral P2Y(6) receptors along the rat proximal tubule: functional and molecular characterization. Journal of the American Society of Nephrology, 12(8), 1640 - 1647.
Bailey MA, Unwin RJ, Shirley DG (2001). In vivo inhibition of renal 11beta-hydroxysteroid dehydrogenase in the rat stimulates collecting duct sodium reabsorption. Clinical Science, 101(2), 195 - 198.
Blackwell VC, Salis P, GROVES RW, Baldeweg SE, Conway GS, Unwin RJ (2001). Partial lipodystrophy, polycystic ovary syndrome and proteinuria: a common link to insulin resistance?. Journal of the Royal Society of Medicine, 94(5), 238 - 240.
Simeoni M, Unwin RJ, Shirley DG, Capasso G, Boyde A (2001). Red laser video-rate scanning confocal microscopy in vivo: experience in studies of renal tubular function.
Marks J, Debnam ES, Norgate D, Srai SKS, Unwin RJ (2001). Detection of glucagon receptor (GR) mRNA in defined nephron segments: the effect of streptozotocin-induced diabetes on mRNA expression.
Biller KJ, Unwin RJ, Shirley DG (2001). Distal tubular electrolyte transport during inhibition of renal 11β- hydroxysteroid dehydrogenase. American Journal of Physiology - Renal Physiology, 280(1), F172 - F179.
Walter SJ, Shirley DG, Folkerd EJ, Unwin RJ (2001). Effects of the potassium channel blocker barium on sodium and potassium transport in the rat loop of Henle in vivo . Experimental Physiology, 86(4), 469 - 474.
Turner CM, Vonend OW, Gretz N, Srai SKS, Burnstock G, Unwin RJ (2001). P2 nucleotide receptors expression in a rat model of polycystic kidney disease.

2000

Bruce LJ, Wrong O, Toye AM, Young MT, Ogle G, Ismail Z, Sinha AK, McMaster P, Hwaihwanje I, Nash GB, Hart S, Lavu E, Palmer R, Othman A, Unwin RJ, Tanner MJA (2000). Band 3 mutations, renal tubular acidosis and South-East Asian ovalocytosis in Malaysia and Papua New Guinea: loss of up to 95% band 3 transport in red cells (vol 350, pg 41, 2000). BIOCHEM J, 351, 839 - 839.
Thompson A, Bailey MA, Michael AE, Unwin RJ (2000). Effects of changes in dietary intake of sodium and potassium and of metabolic acidosis on 11 beta-hydroxysteroid dehydrogenase activities in rat kidney. EXP NEPHROL, 8(1), 44 - 51.
Bruce LJ, Wrong O, Toye AM, Young MT, Ogle G, Ismail Z, Sinha AK, McMaster P, Hwaihwanje I, Nash GB, Hart S, Lavu E, Palmer R, Othman A, Unwin RJ, Tanner MJ (2000). Band 3 mutations, renal tubular acidosis and South-East Asian ovalocytosis in Malaysia and Papua New Guinea: loss of up to 95% band 3 transport in red cells. Biochemical Journal, 350 Pt, 41 - 51.
Unwin RJ, Walter SJ, Giebisch G, Capasso G, Shirley DG (2000). Localization of diuretic effects along the loop of Henle: an in vivo microperfusion study in rats. Clinical Science, 98(4), 481 - 488.
Bailey MA, Turner C, Imbert-Teboul M, Srai K, Burnstock G, Unwin RJ (2000). P2Y(6) receptors in isolated rat nephron segments. FASEB J, 14(4), A139 - A139.
(2000). Axial distribution and characterization of basolateral P2Y receptors along the rat renal tubule. Kidney International, 58(5), 1893 - 1901.
Marks J, Debnam ES, Unwin RJ, Srai SK (2000). Potential role for purinoceptors in the regulation of glucose transport across isolated rat renal brush border membrane.
Nathwani NC, Unwin R, Brook CG, Hindmarsh PC (2000). The influence of renal and cardiovascular abnormalities on blood pressure in Turner syndrome. Clinical Endocrinology, 52(3), 371 - 377.
Nathwani NC, Unwin R, Brook CG, Hindmarsh PC (2000). Blood pressure and Turner syndrome. Clinical Endocrinology, 52(3), 363 - 370.
Norden AGW, Scheinman SJ, Deschodt-Lanckman M, Lapsley M, Nortier JL, Thakker RV, Unwin RJ, Wrong O (2000). Tubular proteinura defined by a study of Dent's (CLCN5 mutation) and other tubular diseases. Kidney International, 57(240), 249 - .
Norden AGW, Lapsley M, Thakker RV, Unwin RJ, Verroust P, Wrong O (2000). The tubular proteinuria of Dent.
Shirley DG, Unwin RJ (2000). Adrenal steroids and the kidney: 11β- hydroxysteroid dehydrogenase and renal function.
Shirley DG, Bailey MA, Unwin RJ (2000). Corticosterone stimulates sodium reabsorption in collecting ducts during in vivo inhibition of 11 β-hydroxysteroid dehydrogenase.
Thompson A, Bailey MA, Michael AE, Unwin RJ (2000). Effects of changes in dietary intake of sodium and potassium and of metabolic acidosis on 11β- hydroxysteroid dehydrogenase (11β HSD) activities in rat kidney. Experimental Nephrology, 8(1), 44 - 51.
Turner C, Vonend O, Nathan S, Burnstock G, Unwin RJ (2000). Detection of P2X receptors in autosomal dominant polycystic kidney disease (ADPKD) tissue.
Unwin RJ, Walter SJ, Giebisch G, Capasso G, Shirley DG (2000). Localisation of diuretic effects along the loop of Henle: an in vivo microperfusion study in rats . Clinical Science, 98(4), 481 - 488.
Bailey MA, Hillman KA, Unwin RJ (2000). P2 receptors in the kidney. Journal of the Autonomic Nervous System, 81(1), 264 - 270.
Bailey MA, Unwin RJ, Shirley DG (2000). Inhibition of renal 11β-hydroxysteroid dehydrogenase: effect on sodium reabsorption in the collecting duct.
Bailey MA, Imbert-Teboul M, Burnstock G, Unwin RJ (2000). ATP-stimulated phosphoinositide metabolism in rat glomeruli is not enhanced by acute sympathectomy.
Bailey MA, Bailly C, Imbert-Teboul M, Unwin RJ (2000). The endothelin-A receptor is present along the rat thin descending limb of Henle.
Capasso G, Unwin RJ, Ciani G, Rizzo A, Russo F, Pica A, De Santo NG (2000). Inhibition of neutral endopeptidase potentiates the effects of atrial natriuretic peptide on acute cyclosporin-induced nephrotoxicity. Nephron, 86(3), 298 - 305.
Dellow EL, Unwin RJ, Miller RF (2000). Presentation, diagnosis, and management of renal failure in patients with HIV infection. AIDS Patient Care and STDs, 14(2), 71 - 77.
Harada H, Chan CM, Loesch A, Unwin RJ, Burnstock G (2000). Induction of proliferation and apoptotic cell death via P2Y and P2X receptors, respectively, in rat glomerular mesangial cells. Kidney International, 57(3), 949 - 958.
Laing C, Thomas DJ, Mathias CJ, Unwin RJ (2000). Headache, hypertension and Horner's syndrome. Journal of the Royal Society of Medicine, 93(10), 535 - 536.
Norden AG, Scheinman SJ, Deschodt-Lanckman MM, Lapsley M, Nortier JL, Thakker RV, Unwin RJ, Wrong O (2000). Tubular proteinuria defined by a study of Dent's (CLCN5 mutation) and other tubular diseases. Kidney International, 57(1), 240 - 249.
Thompson A, Bailey MA, Michael AE, Unwin RJ (2000). Effects of changes in dietary intake of sodium and potassium and of metabolic acidosis on 11beta-hydroxysteroid dehydrogenase activities in rat kidney. Experimental Nephrology, 8(1), 44 - 51.
Laing C, Unwin RJ (2000). Are calcium antagonists effective in preventing complications of hypertension and progression of renal disease?. Current Opinion in Nephrology and Hypertension, 9(5), 489 - 495.

1999

Norden AGW, Asplin J, Deschodt-Lanckman MM, Lapsley M, Nortier JL, Scheinman SJ, Unwin RJ, Wrong OM (1999). Low molecular weight ('tubular') proteinuria in patients with mutations of the CLCN5 renal chloride channel gene.. KIDNEY INT, 55(6), 2548 - 2548.
Kissmeyer L, Kong C, Cohen J, Unwin RJ, Woolfson RG, Neild GH (1999). Community nephrology: audit of screening for renal insufficiency in a high risk population. Nephrology Dialysis Transplantation, 14(9), 2150 - 2155.
Norden AGW, Asplin J, Deschodt-Lanckman MM, Langman CB, Lapsley M, Nortier JL, Scheinman SJ, Thakker RV, Unwin RJ, Wrong O (1999). Low molecular weight ('tubular') proteinuria in patients with mutations of the CLCN5 renal chloride channel gene.. KIDNEY INT, 55(6), 2581 - 2581.
Yeng CC, Baigent S, Unwin R (1999). Is maintaining the intracellular : extracellular fluid compartment ratio an important consideration in Haemodialysis?. KIDNEY INT, 55(5), 2111 - 2112.
Dellow EL, Unwin RJ, Miller RF, Williams IA, Griffiths MH (1999). Protease inhibitor therapy for HIV infection: the effect on HIV-associated nephrotic syndrome. Nephrology Dialysis Transplantation, 14(3), 744 - 747. doi:10.1093/ndt/14.3.744
Dellow E, Unwin R, Miller R, Williams I, Griffiths M (1999). Protease inhibitor therapy for HIV infection: the effect on HIV-associated nephrotic syndrome. NEPHROL DIAL TRANSPL, 14(3), 744 - 747.
Bailey MA, Imbert-Teboul M, Burnstock G, Unwin RJ (1999). P2-purinoceeptors in the rat outer medullary collecting duct: evidence for two receptor subtypes.
Dunn PM, Burnstock G, Unwin R, Moss SE, Chan CM (1999). Properties of the rat P2X₇ receptor stably expressed in chicken DT40 cells.
Bailey MA, Imbert-Teboul M, Chan CM, Burnstock G, Unwin RJ (1999). P2 purinoceptors in the rat proximal convoluted tubule.
Bailey MA, Imbert-Teboul M, Burnstock G, Unwin RJ (1999). Purinergic and noradrenergic stimulation of phosphoinositide metabolism in isolated rat glomeruli.
Foo M, Unwin RJ (1999). Hypertension in type-2 diabetes mellitus. Geriatric Medicine, 29, 35 - 38.
Foo M, Unwin RJ (1999). Hypertension in type-2 diabetes mellitus. Geriatric Medicine, 29, 39 - 40.
Marks J, Debnam ES, Bailey M, Unwin RJ (1999). Involvement of protein kinase C in control of glucose transport across rat renal brush border membrane (BBM) by glucagon.
Marks J, Debnam ES, Unwin RJ (1999). Protein kinase C (PKC) activation is involved in acute regulation of phlorizin-insensitive glucose transport across isolated renal brush border membrane.
Robertson WG, Longhorn SE, Whitfield HN, Unwin RJ, Mansell MA, Neild GH (1999). The changing pattern of the age at onset of urinary stone disease in the UK. Proceedings 8th Symposium on Urolithiasis, , 165 - 168.
Stocking CJ, Slater JM, Unwin RJ, Walter S, Folkerd E (1999). An automated technique for the simultaneous determination of cations in nanolitre volumes. Kidney International, 56, 338 - 343.
Thompson A, Michael AE, Unwin RJ (1999). Effects of adrenalectomy on inhibition of 11á-hydroxysteroid dehydrogenase (11HSD) activities by carbenoxolone (CBX).
Unwin RJ, Capasso G (1999). The basis of renal function. In Johnson R, Feehally J (Ed.), Principles of Nephrology (pp. 2 - 2). : Mosby International London.
Walter SJ, Shirley DG, Unwin RJ, Wrong OM (1999). Assessment of urinary acidificaton.
Dellow EL, Unwin RJ, Honour JW (1999). Pontefract cakes can be bad for you: refractory hypertension and liquorice excess. Nephrology Dialysis Transplantation, 14(1), 218 - 220.
Dellow EL, Unwin RJ, Honour JW (1999). Pontefract cakes can be bad for your health: A case report of refractory hypertension secondary to liquorice excess. Nephrology Dialysis Transplantation, 14, 218 - 220.
Bailey M, Capasso G, Agulian S, Giebisch G, Unwin R (1999). The relationship between distal tubular proton secretion and dietary potassium depletion: evidence for up-regulation of H+ -ATPase. Nephrology Dialysis Transplantation, 14(6), 1435 - 1440.
Mistry H, Sutton PM, Walter MF, Sumeray MS, Woolfson R, Unwin RJ (1999). Urinary neutral endopeptidase activity: a possible marker for renal damage following cardiac surgery.. KIDNEY INT, 55(6), 2550 - 2550.

1998

Unwin R, Capasso G, Wilcox C (1998). Diuretic use in edema and hypertension. In Wilcox C, Brady H (Ed.), Therapy in Nephrology and Hypertension. A Companion to Brenner and Rector's The Kidney (pp. 654 - 664). : W.B. Saunders Company.
Chan CM, Unwin RJ, Burnstock G (1998). Potential functional roles of extracellular ATP in kidney and urinary tract. EXP NEPHROL, 6(3), 200 - 207.
Shirley DG, Walter SJ, Unwin RJ, Giebisch G (1998). Contribution of Na+-H+ exchange to sodium reabsorption in the loop of henle: a microperfusion study in rats. The Journal of Physiology, 513(Pt 1), 243 - 249.
Sewell KJ, Shirley DG, Michael AE, Thompson A, Norgate DP, Unwin RJ (1998). Inhibition of renal 11beta-hydroxysteroid dehydrogenase in vivo by carbenoxolone in the rat and its relationship to sodium excretion. CLIN SCI COLCH, 95(4), 435 - 443.
Chan CM, Unwin RJ, Bardini M, Oglesby IB, Ford AP, Townsend N, Burnstock G (1998). Localization of P2X1 purinoceptors by autoradiography and immunohistochemistry in rat kidneys. AM J PHYSIOL, 274(4 Pt 2), F799 - F804.
Williams DI, Williams DJ, Williams IG, Unwin RJ, Griffiths MH, Miller RF (1998). Presentation, pathology, and outcome of HIV associated renal disease in a specialist centre for HIV/AIDS. SEX TRANSM INFECT, 74(3), 179 - 184.
Shirley DG, Walter SJ, Folkerd EJ, Unwin RJ, Bailey MA (1998). Transepithelial electrochemical gradients in the proximal convoluted tubule during potassium depletion in the rat. The Journal of Physiology, 513(Pt 2), 551 - 557.
Dellow EL, Harley KE, Unwin RJ, Wrong O, Winter GB, Parlins BJ (1998). Amelogenesis imperfecta, nephrocalcinosis, and hypocalciuria syndrome in two siblings from a large family with consanguineous parents. Nephrology Dialysis Transplantation, 13(12), 3193 - 3196.
Bruce LJ, Unwin RJ, Wrong O, Tanner MJ (1998). The association between familial distal renal tubular acidosis and mutations in the red cell anion exchanger (band 3, AE1) gene.. Biochem Cell Biol, 76(5), 723 - 728.
Sewell KJ, Shirley DG, Michael AE, Thompson A, Norgate DP, Unwin RJ (1998). Inhibition of renal 11 beta-hydroxysteroid dehydrogenase in vivo by carbenoxolone in the rat and its relationship to sodium excretion. CLIN SCI, 95(4), 435 - 443.
Unwin RJ (1998). Exploring the function of the intact kidney - Introduction. EXP NEPHROL, 6(5), 381 - 381.
Blaikley JF, Sutton PM, Walter MF, Sumeray MS, Woolfson R, Unwin RJ (1998). Neutral endopeptidase enzymuria following cardiac bypass surgery. J PHYSIOL-LONDON, 509P, 82P - 83P.
Debnam ES, Marks J, Dong R, Srai SK, Unwin RJ (1998). cAMP regulates SGLT-mediated glucose transport across isolated rat renal brush-border membrane.
Walter MF, Unwin RJ (1998). The effect of chronic inhibition of neutral endopeptidase on proximal tubular function in the rat: a micropuncture study. J PHYSIOL-LONDON, 507P, 39P - 40P.
Shirley DG, Walter SJ, Folkerd EJ, Unwin RJ (1998). Bumetanide-induced potassium secretion in perfused loops of Henle in anaesthetized rats: effect of barium. J PHYSIOL-LONDON, 507P, 40P - 40P.
Walter MF, Unwin RJ (1998). Neutral endopeptidase activity in rat urine increases following anaesthesia and surgery. J PHYSIOL-LONDON, 507P, 42P - 42P.
Chan CM, Unwin RJ, Burnstock G (1998). Immunohistochemical localization of P2X₁ and P2X₆ receptors along the normal rat nephron.
Chan CM, Hillman K, Moss S, Unwin RJ, Burnstock G (1998). Putative cytolytic P2X₇ receptor in diabetic rat kidney and its stable transfection in lymphocytes.
Chan CM, Unwin RJ, Bardini M, Oglesby IB, Ford APDW, Townsend-Nicholson A, Burnstock G (1998). Localization of the P2X₁ purinoceptors by autoradiography and immunohistochemistry in rat kidneys. American Journal of Physiology, 274, F799 - 804.
Chan CM, Unwin RJ, Burnstock G (1998). Potential for functional roles of extracellular ATP in the kidney and urinary tract. Experimental Nephrology, 6, 200 - 207.
Bailey MA, Imbert-Teboul M, Burnstock G, Unwin RJ (1998). P2-Purinoceptors in the rat thin limbs of Henle.
Bailey MA, Fletcher RM, Woodrow DF, Unwin RJ, Walter SJ (1998). Upregulation of H+-ATPase in the distal nephron during potassium depletion: structural and functional evidence. American Journal of Physiology, 275(6), F878 - F884.
Blaikley JF, Sutton PM, Walter MF, Sumeray MS, Woolfson R, Unwin R (1998). Neutral endopeptidase enzymuria following cardiac bypass surgery.
Boyde A, Capasso G, Unwin R (1998). Conventional and confocal epi-reflection and fluorescence-microscopy of the rat kidney in vivo. Experimental Nephrology, 6, 398 - 408.
Chan CM, Unwin RJ, Burnstock G (1998). Variable co-localization of P2X₁ and P2X₂ receptors along the rat renal vasculature.
Debnam ES, Marks J, Dong R, Srai SKS, Unwin RJ (1998). cAMP upregulates SGLT-mediated glucose transport across isolated rat renal brush-border membrane.
Debnam ES, Marks J, Unwin RJ, Srai SKS (1998). Circulatory cAMP enhances SGLT-mediated glucose transport at enterocyte BBM.
Karet FE, Gainza FJ, Gyory AZ, Unwin RJ, Wrong OM, Tanner MJ, Nayir A, Santos F, Hulton SA, Bakkalogou A, Ozen S, Cunningham MJ, DiPietro A, Walker WG, Lifton RP (1998). Mutations in the chloride-bicarbonate exchanger gene AE1 cause autosomal dominant but not autosomal recessive distal renal tubular acidosis. Proceedings of the National Academy of Sciences of the United States of America, 95, 6337 - 6342.
Marks J, Debnam ES, Dong R, Srai SK, Unwin RJ (1998). Differential effect of glucagon and cAMP on glucose transport across the rat renal brush border membrane (BB).
Marks J, Debnam ES, Unwin RJ (1998). Rapid stimulation by pancreatic glucagon of facilitated glucose transport across luminal membrane prepared from isolated rat renal cortex.
Norden ACN, Asplin J, Deschodt-Lanckman M, Lapsley M, Nortier JL, Scheinman SJ, Thakker RV, Unwin RJ, Wrong O (1998). Quantitative definition of tubular proteinuria based on studies of patients with mutations of the CLCN5 chloride channel gene (Dents disease and x-linked recessive nephrolithiasis).
Sewell KJ, Shirley DG, Michael AE, Thompson A, Norgate DP, Unwin RJ (1998). In vivo inhibition of renal 11β-hydroxsteroid dehydrogenase by carbenoxolone in the rat and its relationship to sodium excretion. Clinical Science, (95), 435 - 443.
Shirley DG, Sewell KJ, Unwin RJ (1998). Inhibition of 11 β-hydroxysteroid dehydrogenase (11 β-HSD) in vivo stimulates distal tubular potassium secretion.
Shirley DG, Unwin RJ (1998). Renal failure and andrology - Structure and function of the kidney. European Urology, 34, - .
Shirley DG, Walter SJ, Unwin RJ, Giebisch G (1998). Contribution of Na⁺/H⁺ exchange to sodium reabsorption in the thick ascending limb of Henle: A microperfusion study in rats. The Journal of Physiology, 513, 243 - 249.
Thompson A, Bailey M, Michael A, Unwin RJ (1998). Effect of metabolic acidosis on renal 11 β-hydroxysteroid dehydrogenase (11β HSD) activities in rat kidney.

1997

Bailey MA, Unwin RJ, Walter SJ (1997). Functional evidence for up-regulation of H+ ATPase during potassium depletion. KIDNEY INT, 52(1), 265 - 265.
Walter M, Taylor M, Cagag S, Unwin R (1997). The renal effects of chronic inhibition of neutral endopeptidase (NEP, EC 3.4.24.11) in the rat.. J AM SOC NEPHROL, 8, A1898 - A1898.
Bruce LJ, Cope DL, Jones GK, Schofield AE, Burley M, Povey S, Unwin RJ, Wrong O, Tanner MAJ (1997). Familial distal renal tubular acidosis is associated with mutations in the red cell anion exchange. J CLIN INVEST, 100, 1 - 15.
Debnam ES, Unwin RJ, Marks J, Oliva C (1997). Upregulation of phlorizin-insensitive glucose transport across renal brush border (BB) membrane during diabetes mellitus.
Capasso G, Unwin RJM, Forgacs I (1997). The kidney: fluid and electrolyte balance and acid-base regulation. In (Ed.), Essential Clinical Physiology (pp. - ). : Chapman and Hall Press, 1997..
Cope L, Bruce LJ, Schofield AE, Unwin RJ, Wrong OM, Tanner M (1997). Altered red cell anion exchanger (Band 3, AE1) associated with familial distal renal tubular acidosis. Journal of Clinical Investigation, , - .
Unwin RJ, Williams A (1997). Prolonged elevation of serum creatinine kinase (CK) without renal failure after ingestion of ecstasy. Nephrology Dialysis Transplantation, 12, 361 - 362.
Unwin RJ, Dollery CT, Boobis AR, Burley DM (1997). Epoetin. Therapeutic Drugs. In (Ed.), (pp. - ). : Churchill Livingstone 1997..
Unwin RJ, Capasso G, Seldin D, Giebisch G (1997). Hypertension and its treatment: The place of diuretics. Diuretic agents:. In (Ed.), Clinical Physiology and Pharmacology (pp. - ). : Academic Press, 1997..
Walter M, Unwin RJ, Nortier J, Deschodt-Lanckman M (1997). Enhancing endogenous effects of natriuretic peptides: inhibitors of neutral endopeptidase (EC3.4.24.11) and phosphodiesterase. Current Opinion in Nephrology and Hypertension, 6, 468 - 473.
Bruce LJ, Cope DL, Jones GK, Schofield AE, Burley M, Povey S, Unwin RJ, Wrong O, Tanner MJ (1997). Familial distal renal tubular acidosis is associated with mutations in the red cell anion exchanger (Band 3, AE1) gene. J CLIN INVEST, 100(7), 1693 - 1707.
Williams A, Unwin R (1997). Prolonged elevation of serum creatine kinase (CK) without renal failure after ingestion of ecstasy [letter]. NEPHROL DIAL TRANSPLANT, 12(2), 361 - 362.
Bailey MA, Capasso G, Unwin RJ, Walter SJ (1997). Effect of pH on reabsorptive fluxes during in vivo microperfusion of Henle's loop in anaesthetized rats. J PHYSIOL-LONDON, 505P, 109P - 109P.
Debnam ES, Unwin RJ, Marks J, Oliva C (1997). Diabetes mellitus promotes phlorizin-insensitive but not SGLT-mediatd glucose transport across isolated rat renal brush-border membrane..
Unwin R, Stidwell R, Taylor S, Capasso G (1997). The effects of respiratory alkalosis and acidosis on net bicarbonate flux along the rat loop of Henle in vivo.. Am J Physiol, 273(5 Pt 2), F698 - F705.
Debnam ES, Unwin RJ, Marks J, Oliva C (1997). Upregulation of phlorizin(PZ)-insensitive glucose transport across the renal apical brush border membrane (BBM) in a rat model of insulin-dependent diabetes mellitus (DM)..
Chan CM, Bardini M, Unwin RJ, Burnstock G (1997). Immunohistochemical localisation of P2X(1) purinoceptors along the rat renal vasculature.. J AM SOC NEPHROL, 8, A1588 - A1588.
Bruce L, Cope D, Jones G, Schofield A, Burley MW, Povey S, Unwin R, Wrong O, Tanner M (1997). Dominantly inherited distal renal tubular acidosis (dRTA) is associated with mutations in the red cell anion exchanger (BAND 3, AE1) gene.. J AM SOC NEPHROL, 8, A1788 - A1788.
Chan CM, Unwin RJ, Burnstock G (1997). RT-PCR microlocalisation of P2Y(2) purinoceptor mRNA along the rat nephron.. J AM SOC NEPHROL, 8, A2013 - A2013.
Walter SJ, Unwin RJ, Shirley DG (1997). Effect of barium on sodium reabsorption in perfused loops of Henle in anaesthetized rats. J PHYSIOL-LONDON, 501P, P164 - P165.

1996

Unwin R, Wrong O, Cohen E, Tanner M, Thakker R (1996). Unravelling of the molecular mechanisms of kidney stones - Report of a meeting of physicians and scientists, University College London Medical School, London. LANCET, 348(9041), 1561 - 1565.
Singer M, Millar C, Stidwill R, Unwin R (1996). Bladder epithelial oxygen tension--a new means of monitoring regional perfusion? Preliminary study in a model of exsanguination/fluid repletion.. Intensive Care Med, 22(4), 324 - 328.
Parry SM, Walter MF, Simpson CF, Unwin RJ (1996). The application of capillary electrophoresis to the analysis of renal tubular fluid: Peptide and electrolyte assays.. KIDNEY INT, 50(5), 1796 - 1796.
Bailey MA, Fletcher RM, Woodrow DF, Unwin RJ, Walter SJ (1996). Redistribution of H-ATPase in cortical distal nephron segments of the K-depleted rat.. KIDNEY INT, 50(5), 1812 - 1812.
Sewell KJ, Shirley DG, Michael AE, Thompson A, Norgate DP, Unwin RJ (1996). Changes in the urinary Na+:K+ ratio following inhibition of renal 11 beta-hydroxysteroid dehydrogenase (11 beta-HSD) in anaesthetized rats. J PHYSIOL-LONDON, 497P, P90 - P91.
Unwin R, Ligueros M, Capasso G (1996). Major cations in hypertension. J NEPHROL, 9(6), 273 - 279.
Debnam ES, Unwin RJ (1996). Hyperglycemia and intestinal and renal glucose transport: implications for diabetic renal injury.. Kidney Int, 50(4), 1101 - 1109.
Michael AE, Thompson A, Norgate DP, Sewell KJ, Shirley DG, Unwin RJ (1996). Inhibition of renal prostaglandin (PG) and glucocorticoid inactivation by carbenoxolone: Relationship to renal sodium excretion.. J AM SOC NEPHROL, 7(9), A2000 - A2000.
Shirley DG, Walter SJ, Unwin RJ (1996). Mechanism of the impaired natriuretic response to frusemide during sodium depletion: a micropuncture study in rats.. Clin Sci (Lond), 91(3), 299 - 305.
Parry SM, Simpson CF, Walter MF, Unwin RJ (1996). A ''new'' ultramicro-analytical method for measurement of inorganic ions in renal tubular fluid. J AM SOC NEPHROL, 7(9), A0203 - A0203.
Chan CM, Unwin RJ, Burnstock G (1996). Autoradiographic localization of P2U purinoceptors along the rat renal tubule.. J AM SOC NEPHROL, 7(9), A2127 - A2127.
Simon DB, Karet FE, Rudin A, Trachtman H, Fischbach M, Calo L, Hulton S, Sechi G, Unwin R, Lifton RP (1996). The molecular basis of inherited hypokalemic alkalosis: Bartter's and Gitelman's syndromes.. J AM SOC NEPHROL, 7(9), A1871 - A1871.
Walter SJ, Shirley DG, Unwin RJ (1996). Effect of vasopressin on renal lithium reabsorption: a micropuncture and microperfusion study.. Am J Physiol, 271(1 Pt 2), F223 - F229.
Walter SJ, Shirley DG, Unwin RJ (1996). Effect of vasopressin on renal lithium reabsorption: A micropuncture and microperfusion study. AM J PHYSIOL-RENAL, 40(1), F223 - F229.
Bailey MA, Unwin RJ (1996). The effect of bafilomycin on transepithelial potential difference in the distal tubule of anaesthetized rats. J PHYSIOL-LONDON, 493P, P69 - P69.
Bailey MA, Shirley DG, Unwin RJ, Walter SJ (1996). Transepithelial potential difference in proximal tubules of anaesthetized potassium-depleted rats. J PHYSIOL-LONDON, 493P, P77 - P78.
Bailey MA, Fletcher RM, Woodrow DF, Unwin RJ, Walter SJ (1996). Redistribution of H+-ATPase in cortical distal nephron segments of the K+-depleted rat. J PHYSIOL-LONDON, 493P, P95 - P95.
Unwin RJ, Shirley DG, Walter SJ, Capasso G, Giebisch G (1996). Proximal tubular contribution to the effects of diuretics in perfused loops of Henle of anaesthetized rats. J PHYSIOL-LONDON, 493P, P96 - P96.
Sampson M, Kong C, Patel A, Unwin R, Jacobs HS (1996). Ambulatory blood pressure profiles and plasminogen activator inhibitor (PAI-1) activity in lean women with and without the polycystic ovary syndrome. CLIN ENDOCRINOL, 45(5), 623 - 629.

1995

WALTER SJ, UNWIN RJ, SHIRLEY DG (1995). IMPAIRED NATRIURETIC RESPONSE TO FRUSEMIDE IN SODIUM-DEPLETED, ANESTHETIZED RATS - ROLE OF THE LOOP OF HENLE. J PHYSIOL-LONDON, 489P, P84 - P85.
BOYDE A, WALTER M, UNWIN R, TOROK K (1995). THE USE OF LASER-SCANNING CONFOCAL MICROSCOPY TO STUDY THE UPTAKE OF FLUORESCENT INSULIN IN THE RENAL TUBULE IN-VIVO. J PHYSIOL-LONDON, 489P, P3 - P3.
KONG CH, UNWIN RJ, POURIA S, THOMPSON FD (1995). NOCTURNAL BLOOD-PRESSURE (BP) AND RENAL-FAILURE. J AM SOC NEPHROL, 6(3), 393 - 393.
MILLAR CGM, WOOLFSON RG, UNWIN RJ, NEILD GH (1995). EFFECTS OF ADENOSINE RECEPTOR SUBTYPES IN EXPERIMENTAL RENAL ISCHEMIA-REPERFUSION INJURY. J AM SOC NEPHROL, 6(3), 984 - 984.
Ganz MB, Kasner SE, Unwin RJ (1995). Nitric oxide alters cytosolic potassium in cultured glomerular mesangial cells.. Am J Physiol, 268(6 Pt 2), F1081 - F1086.
GANZ MB, KASNER SE, UNWIN RJ (1995). NITRIC-OXIDE ALTERS CYTOSOLIC POTASSIUM IN CULTURED GLOMERULAR MESANGIAL CELLS. AM J PHYSIOL-RENAL, 37(6), F1081 - F1086.
KITAMURA K, BURTON S, UNWIN R, FINE LG (1995). INTRAGLOMERULAR TRANSPLANTATION OF GENETICALLY-ENGINEERED MESANGIAL CELLS IN-VIVO. KIDNEY INT, 47(2), 689 - 689.
UNWIN RJ, WALTER SJ, SHIRLEY DG (1995). EFFECT OF BARIUM ON SODIUM-REABSORPTION IN PERFUSED LOOPS OF HENLE - IS THE PARS RECTA INVOLVED. KIDNEY INT, 47(2), 663 - 663.
WALTER SJ, UNWIN RJ, SHIRLEY DG (1995). LITHIUM REABSORPTION IN LOOPS OF HENLE OF ANESTHETIZED RATS - INHIBITORY EFFECT OF LOW-SODIUM PERFUSATE. J PHYSIOL-LONDON, 483P, P168 - P169.
Unwin R, Capasso G, Giebisch G (1995). Bicarbonate transport along the loop of Henle effects of adrenal steroids.. Am J Physiol, 268(2 Pt 2), F234 - F239.
UNWIN R, CAPASSO G, GIEBISCH G (1995). BICARBONATE TRANSPORT ALONG THE LOOP OF HENLE - EFFECTS OF ADRENAL-STEROIDS. AM J PHYSIOL-RENAL, 37(2), F234 - F239.
CAPASSO G, SAVIANO C, UNWIN R, VINCIGUERRA M, CIANI F, MOLLICA F, MEDOLLA G, TUCCI A, DESANTO NG (1995). EFFECT OF MEDULLARY HYPOTONICITY ON NET BICARBONATE TRANSPORT ALONG THE LOOP OF HENLE (LOH). KIDNEY INT, 47(2), 667 - 667.
CALAM J, CAPASSO G, MEHTA S, PLAYFORD R, UNWIN R (1995). EFFECTS OF PEPTIDE TYROSINE TYROSINE (PYY) ON RENAL-FUNCTION - A POTENTIAL MEDIATOR OF POSTPRANDIAL NATRIURESIS. KIDNEY INT, 47(2), 682 - 683.
PLAYFORD RJ, MEHTA S, UPTON P, RENTCH R, MOSS S, CALAM J, BLOOM S, PAYNE N, GHATEI M, EDWARDS R, UNWIN R (1995). EFFECT OF PEPTIDE YY ON HUMAN RENAL-FUNCTION. AM J PHYSIOL-RENAL, 37(4), F754 - F759.

1994

Capasso G, Unwin R, Ciani F, De Tommaso G, Vinciguerra M, Russo F, De Santo NG (1994). The effect of acute metabolic alkalosis on bicarbonate transport along the loop of Henle. The role of active transport processes and passive paracellular backflux.. Pflugers Arch, 429(1), 44 - 49.
Unwin R, Capasso G, Giebisch G (1994). Potassium and sodium transport along the loop of Henle: effects of altered dietary potassium intake.. Kidney Int, 46(4), 1092 - 1099.
UNWIN RJ, WALTER SJ, SHIRLEY DG (1994). VASOPRESSIN STIMULATES LITHIUM REABSORPTION IN PERFUSED LOOPS OF HENLE. J AM SOC NEPHROL, 5(3), 280 - 280.
SCHOFIELD AE, TANNER MJA, UNWIN RJ, WRONG OM (1994). ALTERATIONS IN THE RBC ANION TRANSPORTER (BAND-3) ASSOCIATED WITH FAMILIAL DISTAL RENAL TUBULAR-ACIDOSIS (DRTA). J AM SOC NEPHROL, 5(3), 372 - 372.
MILLAR CGM, SINGER M, STIDWILL R, UNWIN RJ, NEILD GH (1994). BLADDER EPITHELIAL OXYGEN-TENSION (BEPO2) IS AN INDEX OF RENAL PERFUSION. J AM SOC NEPHROL, 5(3), 608 - 608.
MILLAR CGM, WOOLFSON RG, UNWIN RJ, NEILD GH (1994). ISCHEMIC PRECONDITIONING DOES NOT PROTECT THE KIDNEY AGAINST ISCHEMIA-REPERFUSION INJURY. J AM SOC NEPHROL, 5(3), 904 - 904.
Hropot M, Klaus E, Unwin R, Giebisch G (1994). Diminished diuretic and natriuretic response to furosemide in potassium-depleted rats.. Ren Physiol Biochem, 17(1), 10 - 20.
KITAMURA M, BURTON S, ENGLISH J, YOKOO T, UNWIN R, SHIMIZU F, FINE LG (1994). IN-VIVO TRANSFER OF A MUTANT-GENE, WHICH ENCODES THE ACTIVE FORM OF TGF-BETA(1), SUPPRESSES INFLAMMATORY RESPONSES IN THE GLOMERULUS. J AM SOC NEPHROL, 5(3), 695 - 695.
CAPASSO G, RIZZO A, UNWIN R, SAVIANO C, CIANI F, DESANTO NG (1994). THE EFFECT OF ENDOPETPTIDASE INHIBITION BY THIORPHAN ON EXPERIMENTAL CYCLOSPORINE NEPHROTOXICITY. J AM SOC NEPHROL, 5(3), 919 - 919.
Kitamura M, Taylor S, Unwin R, Burton S, Shimizu F, Fine LG (1994). Gene transfer into the rat renal glomerulus via a mesangial cell vector: site-specific delivery, in situ amplification, and sustained expression of an exogenous gene in vivo.. J Clin Invest, 94(2), 497 - 505. doi:10.1172/JCI117361
Capasso G, Unwin R, Ciani F, De Santo NG, De Tommaso G, Russo F, Giebisch G (1994). Bicarbonate transport along the loop of Henle. II. Effects of acid-base, dietary, and neurohumoral determinants.. J Clin Invest, 94(2), 830 - 838. doi:10.1172/JCI117403
Cairns HS, Dawnay A, Woolfson RG, Unwin RJ (1994). Evaluation of therapy for cast nephropathy: failure of colchicine to alter urinary Tamm Horsfall glycoprotein excretion in normal subjects.. Exp Nephrol, 2(4), 257 - 258.
Unwin RJ, Walter SJ, Shirley DG (1994). Lithium reabsorption in perfused loops of Henle: effects of perfusion rate and bumetanide.. Am J Physiol, 266(5 Pt 2), F806 - F812.
BOYDE A, UNWIN R, CAPASSO G, WALTER M (1994). APPLICATION OF IN-VIVO CONFOCAL MICROSCOPY TO DYNAMIC STUDIES OF RENAL TUBULE FUNCTION. J AM SOC NEPHROL, 5(3), 306 - 306.

1993

Moss SF, Waheed A, Beardshall K, Gill J, Adamson D, Unwin R, Calam J (1993). Use of endoscopic biopsies and microelectrodes to study human gastric acid secretion in vitro.. Neuropeptides, 25(4), 265 - 269.
Wilkins MR, Unwin RJ, Kenny AJ (1993). Endopeptidase-24.11 and its inhibitors: potential therapeutic agents for edematous disorders and hypertension.. Kidney Int, 43(2), 273 - 285.
Giebisch G, Klein-Robbenhaar G, Klein-Robbenhaar J, Ratheiser K, Unwin R (1993). Renal and extrarenal sites of action of diuretics.. Cardiovasc Drugs Ther, 7 Suppl 1, 11 - 21.
TAYLOR SA, UNWIN RJ (1993). THE EFFECT OF NEUTRAL ENDOPEPTIDASE INHIBITION ON THE RENAL RESPONSE TO SUBSTANCE-P IN ANESTHETIZED RATS. J PHYSIOL-LONDON, 473, P274 - P274.
UNWIN RJ, WALTER SJ, SAMPSON B, SHIRLEY DG (1993). LITHIUM REABSORPTION IN PERFUSED LOOPS OF HENLE OF ANESTHETIZED RATS. J PHYSIOL-LONDON, 459, P376 - P376.

1992

Ligueros M, Unwin R, Wilkins MR, Humphreys J, Coles SJ, Cleland J (1992). A comparison of the effects of the selective peripheral alpha 1-blocker terazosin with the selective beta 1-blocker atenolol on blood pressure, exercise performance and the lipid profile in mild-to-moderate essential hypertension.. Clin Auton Res, 2(6), 373 - 381.
Wilkins MR, Settle SL, Kirk JE, Taylor SA, Moore KP, Unwin RJ (1992). Response to atrial natriuretic peptide, endopeptidase 24.11 inhibitor and C-ANP receptor ligand in the rat.. Br J Pharmacol, 107(1), 50 - 57.
Taylor G, Unwin R, Wilkins M, Capasso G (1992). Arginine derivatives and uraemia.. Lancet, 339(8803), 1243 - .
MOSS SF, UNWIN R, WAHEED A, CALAM J (1992). INHIBITION OF ACID-SECRETION FROM HUMAN ENDOSCOPIC BIOPSIES BY THE GASTRIN RECEPTOR ANTAGONIST CAM-1028. GUT, 33(2), S32 - S32.
SPRINGALL DR, UNWIN R, GANZ MB, BUTTERY LDK, CIANI F, MONCADA S, POLAK JM (1992). RAT MESANGIAL CELLS IN CULTURE CONTAIN NITRIC-OXIDE SYNTHASE IMMUNOREACTIVITY.
SPRINGALL DR, UNWIN R, BUTTERY LDK, MONCADA S, POLAK JM (1992). JUXTAGLOMERULAR CELLS IN RAT-KIDNEY CONTAIN NITRIC-OXIDE SYNTHASE IMMUNOREACTIVITY.
Okusa MD, Unwin RJ, Velázquez H, Giebisch G, Wright FS (1992). Active potassium absorption by the renal distal tubule.. Am J Physiol, 262(3 Pt 2), F488 - F493.

1991

Green R, Giebisch G, Unwin R, Weinstein AM (1991). Coupled water transport by rat proximal tubule.. Am J Physiol, 261(6 Pt 2), F1046 - F1054.
Ligueros M, Unwin R, Wilkins M (1991). Selective alpha 1-adrenoreceptor blockers in the treatment of hypertension: should we be using them more?. Clin Auton Res, 1(3), 251 - 258.
Capasso G, Unwin R, Agulian S, Giebisch G (1991). Bicarbonate transport along the loop of Henle. I. Microperfusion studies of load and inhibitor sensitivity.. J Clin Invest, 88(2), 430 - 437. doi:10.1172/JCI115322
CAPASSO G, GIEBISCH G, UNWIN R (1991). THE EFFECT OF SEVERAL CLASSES OF DIURETIC ON WATER (JV), SODIUM (JNA) AND POTASSIUM (JK) TRANSPORT IN THE ANESTHETIZED RAT LOOP OF HENLE (LOH) INVIVO. J PHYSIOL-LONDON, 438, P65 - P65.
Sutters M, Carmichael DJ, Unwin RJ, Sozi C, Hunter M, Calam J, Lightman SL, Peart WS (1991). 'Low sodium' diuresis and ileal loss in patients with ileostomies: effect of desmopressin.. Gut, 32(6), 649 - 653.
BEARDSHALL K, ADAMSON D, GILL J, UNWIN R, CALAM J (1991). HELICOBACTER-PYLORI RAISES THE PH IN THE JUXTAEPITHELIAL REGION OF THE MUCUS LAYER OF THE GASTRIC ANTRUM AND BODY. GUT, 32(5), A569 - A570.
Capasso G, Unwin R, Giebisch G (1991). Role of the loop of Henle in urinary acidification.. Kidney Int Suppl, 33, S33 - S35.

1990

GREEN R, UNWIN R, WEINSTEIN AM, GIEBISCH G (1990). HYPERTONIC COMPARTMENT IN THE RENAL PROXIMAL TUBULE OF THE RAT. KIDNEY INT, 37(1), 581 - 581.
AGULIAN S, CAPASSO G, GIEBISCH G, UNWIN R (1990). EVIDENCE FOR NET POTASSIUM (K) REABSORPTION AND INCREASED PROTON (H+) SECRETION IN THE DISTAL TUBULE OF POTASSIUM-DEPLETED (LK) ANESTHETIZED RATS. J PHYSIOL-LONDON, 430, P29 - P29.
UNWIN R (1990). BICARBONATE AND CYTOPLASMIC PH. LANCET, 335(8705), 1586 - 1587.
Carmichael DJ, Sutters MS, Unwin RJ, Gordon D, Few J, James VH, Wadsworth J, Peart WS (1990). Time-course and relationship of the early changes in renal sodium excretion and aldosterone secretion during dietary sodium restriction in normal man.. Clin Sci (Lond), 78(6), 605 - 612.
AGULIAN S, CAPASSO G, GIEBISCH G, UNWIN R (1990). BICARBONATE TRANSPORT ALONG THE LOOP OF HENLE - EFFECT OF SPECIFIC TRANSPORT INHIBITORS IN THE ANESTHETIZED RAT. J PHYSIOL-LONDON, 424, P15 - P15.
Unwin RJ, Ganz MD, Sterzel RB (1990). Brain-gut peptides, renal function and cell growth.. Kidney Int, 37(4), 1031 - 1047.
GIEBISCH G, UNWIN RJ (1990). EVIDENCE FOR A DIRECT EFFECT OF VASOACTIVE INTESTINAL POLYPEPTIDE (VIP) AND SULFATED CHOLECYSTOKININ OCTAPEPTIDE (CCK8) ON THE RAT LOOP OF HENLE - A MICROPERFUSION STUDY IN ANESTHETIZED RAT. J PHYSIOL-LONDON, 420, P141 - P141.
CAPASSO G, UNWIN R, GIEBISCH G (1990). BICARBONATE REABSORPTION (JHCO3) BY THE LOOP OF HENLE IS AFFECTED BY CHANGES IN ACID-BASE STATUS. KIDNEY INT, 37(1), 534 - 534.
UNWIN R, CAPASSO G, AGULIAN S, GIEBISCH G (1990). EFFECT OF ADRENAL-STEROIDS ON LOOP OF HENLE BICARBONATE TRANSPORT (JSTARHCO3). KIDNEY INT, 37(1), 548 - 548.
OKUSA MD, UNWIN R, WRIGHT FS, GIEBISCH G, CAPLAN MJ (1990). H+, K+-ATPASE MESSENGER-RNA EXPRESSION IN RAT-KIDNEY. KIDNEY INT, 37(1), 568 - 568.

1989

STERZEL R, GANZ M, PERFETTO M, UNWIN R (1989). VASOACTIVE PEPTIDES (VPS) PROMOTE GROWTH OF CULTURED MESANGIAL CELLS (MCS). KIDNEY INT, 35(1), 307 - 307.
CAPASSO G, UNWIN R, GIEBISCH G (1989). CHARACTERIZATION OF BICARBONATE TRANSPORT IN THE LOOP OF HENLE. KIDNEY INT, 35(1), 452 - 452.
Loon NR, Wilcox CS, Unwin RJ (1989). Mechanism of impaired natriuretic response to furosemide during prolonged therapy.. Kidney Int, 36(4), 682 - 689.
GIEBISCH G, GREEN R, UNWIN R, WEINSTEIN AM (1989). A HYPERTONIC COMPARTMENT IN THE RENAL PROXIMAL TUBULE OF THE ANESTHETIZED RAT. J PHYSIOL-LONDON, 417, P39 - P39.

1988

Unwin RJ, Carmichael DJ, Peart WS (1988). Severe cardiac failure and leukoerythroblastic anaemia in a patient with giant cell arteritis.. J R Soc Med, 81(1), 49 - 51.
CARMICHAEL D, HUNTER M, LIGHTMAN SL, SOZI C, PEART WS, SUTTERS M, UNWIN RJ (1988). URINARY ARGININE VASOPRESSIN EXCRETION FALLS IN ASSOCIATION WITH A WATER DIURESIS ON DIETARY-SODIUM RESTRICTION IN HUMAN-SUBJECTS WITH ILEOSTOMIES. J PHYSIOL-LONDON, 398, P81 - P81.
UNWIN RJ (1988). CORRECTION. REGUL PEPTIDES, 21(1-2), 183 - 183.
CARMICHAEL DJS, LIGHTMAN SL, PEART WS, SUTTERS M, UNWIN RJ (1988). DESMOPRESSIN REVERSES THE DIURESIS THAT OCCURS ON SODIUM RESTRICTION IN HUMAN-SUBJECTS WITH ILEOSTOMIES. J PHYSIOL-LONDON, 399, P49 - P49.
UNWIN RJ, SHIH AC, GIEBISCH G (1988). VASOACTIVE INTESTINAL POLYPEPTIDE (VIP) AND CHOLECYSTOKININ OCTAPEPTIDE (CCK8) REDUCE SODIUM AND WATER REABSORPTION IN THE LOOP OF HENLE. KIDNEY INT, 33(1), 288 - 288.
Calam J, Unwin RJ, Dorudi S, Taylor C, Springer CJ, Peart WS (1988). Effects of vasoactive intestinal polypeptide infusions on renal function in patients with liver disease.. Clin Exp Pharmacol Physiol, 15(6), 491 - 495.

1987

Unwin RJ, Reed T, Thom S, Calam J, Peart WS (1987). Effects of indomethacin and (+/-)-propranolol on the cardiovascular and renin responses to vasoactive intestinal polypeptide (VIP) infusion in man.. Br J Clin Pharmacol, 23(5), 523 - 528.
Calam J, Gordon D, Peart WS, Taylor SA, Unwin RJ (1987). Renal effects of gastrin C-terminal tetrapeptide (as pentagastrin) and cholecystokinin octapeptide in conscious rabbit and man.. Br J Pharmacol, 91(2), 307 - 314.
Unwin RJ, Calam J, Peart WS, Hanson C, Lee YC, Bloom SR (1987). Renal function during bovine neurotensin infusion in man.. Regul Pept, 18(1), 29 - 35.
Weber JN, Thom S, Barrison I, Unwin R, Forster S, Jeffries DJ, Boylston A, Pinching AJ (1987). Cytomegalovirus colitis and oesophageal ulceration in the context of AIDS: clinical manifestations and preliminary report of treatment with Foscarnet (phosphonoformate).. Gut, 28(4), 482 - 487.
CARMICHAEL DJS, PEART WS, UNWIN RJ (1987). RENAL TUBULAR EFFECTS AND CHANGES IN WHOLE-BLOOD CALCIUM-ION ACTIVITY (ACA) DURING CALCIUM-CHLORIDE (CACL2) INFUSION IN MAN. J PHYSIOL-LONDON, 382, P146 - P146.
HANSON C, MAY CN, UNWIN RJ (1987). EFFECT INVITRO OF PARATHORMONE (PTH) AND THE HOMOLOGOUS PEPTIDE FAMILY VASOACTIVE INTESTINAL POLYPEPTIDE (VIP), GLUCAGON AND SECRETIN ON RENIN RELEASE. J PHYSIOL-LONDON, 382, P37 - P37.
Boulter M, Brink A, Mathias C, Peart S, Stevens J, Stewart G, Unwin R (1987). Unusual cranial and abdominal computed tomographic (CT) scan appearances in a case of systemic lupus erythematosus (SLE).. Ann Rheum Dis, 46(2), 162 - 165.
Few JD, Unwin RJ, Carmichael DJ, James VH (1987). Diurnal fluctuation in saliva aldosterone concentration.. J Steroid Biochem, 26(2), 265 - 271.

1986

CARMICHAEL DJS, PEART WS, UNWIN RJ (1986). INVITRO STUDY OF THE RELATIONSHIP BETWEEN WHOLE-BLOOD CA-2+ ION ACTIVITY (ALPHA-CA) AND TOTAL PLASMA CALCIUM-CONCENTRATION IN RABBIT AND MAN. J PHYSIOL-LONDON, 381, P21 - P21.
Carmichael D, Few J, Peart S, Unwin R (1986). Sodium and water depletion in ileostomy patients.. Lancet, 2(8507), 625 - 626.
CARMICHAEL DJS, FEW JD, PEART WS, UNWIN RJ (1986). CHANGES IN SALIVARY ALDOSTERONE (SA) CONCENTRATION DURING DIETARY-SODIUM RESTRICTION IN 2 HEALTHY-MALES. J PHYSIOL-LONDON, 377, P71 - P71.
ALLEN JM, HANSON C, LEE Y, MATTIN R, UNWIN RJ (1986). RENAL EFFECTS OF THE HOMOLOGOUS NEUROPEPTIDES PANCREATIC-POLYPEPTIDE (PP) AND NEUROPEPTIDE Y (NPY) IN CONSCIOUS RABBITS. J PHYSIOL-LONDON, 376, P24 - P24.
WILCOX C, UNWIN R (1986). NATRIURETIC RESPONSE TO FUROSEMIDE DURING PROLONGED ADMINISTRATION. KIDNEY INT, 29(1), 208 - 208.
UNWIN RJ (1986). CORRECTION. CLIN SCI, 70(3), U307 - U307.
CARMICHAEL D, UNWIN R, WADSWORTH J (1986). ATENOLOL FOR ALCOHOL-WITHDRAWAL. NEW ENGL J MED, 314(12), 783 - 783.
Peart WS, Roddis SA, Unwin RJ (1986). Renal electrolyte excretion and renin release during calcium and parathormone infusions in conscious rabbits.. J Physiol, 373, 329 - 341.
Unwin RJ, Mathias CJ, Peart WS, Frankel HL (1986). Renal vascular responses to saralasin in conscious chemically denervated rabbits and patients with tetraplegia.. Clin Exp Hypertens A, 8(6), 919 - 939.

1985

Unwin RJ, Moss S, Peart WS, Wadsworth J (1985). Renal adaptation and gut hormone release during sodium restriction in ileostomized man.. Clin Sci (Lond), 69(3), 299 - 308.
CALAM J, PEART WS, REED T, THOM S, UNWIN RJ (1985). THE INFLUENCE OF INDOMETHACIN AND DL-PROPRANOLOL ON THE CARDIOVASCULAR AND RENIN RESPONSES TO VASOACTIVE INTESTINAL POLYPEPTIDE (VIP) IN MAN. J PHYSIOL-LONDON, 358(JAN), P121 - P121.

1984

Morice A, Unwin R, Sever P (1984). VIP as bronchodilator.. Lancet, 1(8374), 457 - 458.
Calam J, Unwin RJ, Singh J, Dorudi S, Peart WS (1984). Renal function during vasoactive intestinal peptide (VIP) infusions in normal man and patients with liver disease.. Peptides, 5(2), 441 - 443.
Morice AH, Unwin RJ, Sever PS (1984). Vasoactive intestinal peptide as a bronchodilator in asthmatic subjects.. Peptides, 5(2), 439 - 440.
Mathias CJ, Unwin RJ, Pike FA, Frankel HL, Sever PS, Peart WS (1984). The immediate pressor response to saralasin in man: evidence against sympathetic activation and for intrinsic angiotensin II-like myotropism.. Clin Sci (Lond), 66(5), 517 - 524.
Lightman SL, Unwin RJ, Graham K, Dimaline R, McGarrick G (1984). Vasoactive intestinal polypeptide stimulation of prolactin release and renin activity in normal man and patients with hyperprolactinaemia: effects of pretreatment with bromocriptine and dexamethazone.. Eur J Clin Invest, 14(6), 444 - 448.
MORICE AH, UNWIN RJ, SEVER PS (1984). THE BRONCHODILATING EFFECTS OF INTRAVENOUS VASOACTIVE INTESTINAL PEPTIDE IN HUMAN ASTHMATIC SUBJECTS. CLIN SCI, 66(2), P58 - P58.
MORICE A, UNWIN RJ, SEVER PS (1984). INVIVO BRONCHODILATOR ACTIVITY OF VASOACTIVE INTESTINAL PEPTIDE IN THE CAT. AM REV RESPIR DIS, 129(5), 882 - 882.

1983

Bloom SR, Peart WS, Unwin RJ (1983). Neurotensin and antinatriuresis in the conscious rabbit.. Br J Pharmacol, 79(1), 15 - 18.
Calam J, Dimaline R, Peart WS, Unwin R (1983). Studies on the renin response to vasoactive intestinal polypeptide (VIP) in the conscious rabbit.. Br J Pharmacol, 80(1), 13 - 15.
Dimaline R, Peart WS, Unwin RJ (1983). Effects of vasoactive intestinal polypeptide (VIP) on renal function and plasma renin activity in the conscious rabbit.. J Physiol, 344, 379 - 388.
Morice A, Unwin RJ, Sever PS (1983). Vasoactive intestinal peptide causes bronchodilatation and protects against histamine-induced bronchoconstriction in asthmatic subjects.. Lancet, 2(8361), 1225 - 1227.
Calam J, Dimaline R, Peart WS, Singh J, Unwin RJ (1983). Effects of vasoactive intestinal polypeptide on renal function in man.. J Physiol, 345, 469 - 475.
Calam J, Unwin R, Peart WS (1983). Neurotensin stimulates defaecation.. Lancet, 1(8327), 737 - 738.
PEART WS, UNWIN RJ (1983). EFFECTS OF SUBSTANCE-P (SP) ON RENAL-FUNCTION IN CONSCIOUS RABBITS. J PHYSIOL-LONDON, 343(OCT), P51 - P51.
CALAM J, UNWIN RJ, SINGH J, DORUDI S, PEART WS (1983). RENAL-FUNCTION DURING VASOACTIVE INTESTINAL POLYPEPTIDE (VIP) INFUSION IN NORMAL MAN AND IN PATIENTS WITH LIVER-DISEASE. REGUL PEPTIDES, 6(3), 293 - 293.
CALAM J, PEART WS, UNWIN RJ (1983). RENAL EFFECTS OF CHOLECYSTOKININ OCTAPEPTIDE (CCK8) IN THE CONSCIOUS RABBIT. J PHYSIOL-LONDON, 334(JAN), P122 - P122.
CALAM J, UNWIN RJ, PEART WS (1983). NEUROTENSIN STIMULATES DEFECATION IN MAN. GUT, 24(5), A481 - A481.

1982

CALAM J, PEART WS, SINGH J, UNWIN RJ (1982). RENAL-FUNCTION DURING VASOACTIVE INTESTINAL POLYPEPTIDE (VIP) INFUSION IN MAN. J PHYSIOL-LONDON, 332(NOV), P96 - P97.
CALAM J, DIMALINE R, PEART WS, UNWIN RJ (1982). VASOACTIVE INTESTINAL POLYPEPTIDE (VIP) AND RENIN RELEASE IN THE CONSCIOUS RABBIT. J PHYSIOL-LONDON, 329(AUG), P66 - P66.
FRANKEL HL, MATHIAS CJ, PEART WS, UNWIN RJ (1982). INDOMETHACIN INHIBITS RENIN RELEASE TO TILT, ISOPRENALINE AND FRUSEMIDE IN TETRAPLEGIC SUBJECTS. J PHYSIOL-LONDON, 325(APR), P62 - P62.
BLOOM SR, PEART WS, UNWIN RJ (1982). NEUROTENSIN AND RENAL-FUNCTION IN THE CONSCIOUS RABBIT. J PHYSIOL-LONDON, 332(NOV), P95 - P96.
Unwin RJ, Calam J, Peart WS, Dimaline R, Lightman SL (1982). Vipoma and watery diarrhea.. N Engl J Med, 307(6), 377 - 378. doi:10.1056/NEJM198208053070617

1981

GORDON D, PEART WS, RODDIS SA, UNWIN RJ (1981). RENAL-FUNCTION DURING PENTAGASTRIN INFUSION IN CONSCIOUS RABBITS. J PHYSIOL-LONDON, 310(JAN), P40 - P41.
MATHIAS CJ, UNWIN RJ, FRANKEL HL, DAVIES IB, SEVER PS, PEART WS (1981). MECHANISM OF THE IMMEDIATE PRESSOR-RESPONSE TO SARALASIN - STUDIES IN TETRAPLEGIC MAN. CLIN SCI, 61(3), P37 - P37.
FRANKEL HL, MATHIAS CJ, PEART WS, UNWIN RJ (1981). SARALASIN-INDUCED RENAL VASOCONSTRICTION IS DUE TO INTRINSIC ANGIOTENSIN-II ACTIVITY. J PHYSIOL-LONDON, 319(OCT), P72 - P73.
PEART WS, RODDIS SA, UNWIN RJ (1981). INVIVO EVIDENCE FOR RENAL TUBULAR NA-CA COUNTER TRANSPORT. J PHYSIOL-LONDON, 320(NOV), P64 - P65.

Hall AM, Edwards SG, Lapsley M, Connolly JO, Chetty K, O'Farrell S, Unwin RJ, Williams IG (). Subclinical tubular injury in HIV-infected individuals of antiretroviral therapy: A cross-sectional analysis. American Journal of Kidney Diseases, , - .

UCL CONSORTIUM FOR MITOCHONDRIAL RESEARCH