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Prof Martin Crompton

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Personal Profile

Name: Martin Crompton Email: m.crompton@ucl.ac.uk
Title: Prof Tel:
Department: Div of Biosciences Fax:
Position: Emeritus Professor of Biochemistry Address: Department of Structural and Molecular Biology, University College London, Gower Street, WC1E 6BT
Research Domain: Basic Life Sciences, Cardiometabolic Science, Neuroscience, Personalised Medicine Web Page:  

Profile

Research Description

Ischaemic diseases, notably myocardial infarction and stroke, are the leading cause of death and disability throughout the world. Twenty years ago we put forward a mitochondrial model for ischaemia / reperfusion (I/R)injury based on the commonality between factors that induce formation of the permeability transition pore in mitochondria and critical cellular changes in I/R, principally cellular calcium overload, oxidative stress and depleted adenine nucleotides. This led to our identification of cyclosporin A as a potent pore inhibitor able to attenuate I/R injury and of mitochondrial cyclophilin-D as a key component. Current work is aimed at understanding the role of cyclophilin-D in pore formation and on the development of pore inhibitors for use as tools in evaluating permeability transition-mediated mitochondrial dysfunction in cell injury and disease, and as potential therapeutic agents. The cyclophilin work has also been broadened to include the cytosolic isoform, cyclophilin-A, and its role in apoptosis.

Research Activities

The mitochondrial permeability transition pore

Education Description

UCL Collaborators

External Collaborators

Publications

    2012

    • Dube H, Selwood D, Malouitre S, Capano M, Simone MI, Crompton M (2012). A mitochondrial-targeted cyclosporin A with high binding affinity for cyclophilin D yields improved cytoprotection of cardiomyocytes.. Biochem J, 441(3), 901 - 907. doi:10.1042/BJ20111301

    2010

    • Malouitre S, Dube H, Selwood D, Crompton M (2010). Mitochondrial targeting of cyclosporin A enables selective inhibition of cyclophilin-D and enhanced cytoprotection after glucose and oxygen deprivation.. Biochemical Journal, 425, 137 - 148. doi:10.1042/BJ20090332

    2008

    • Gillick K, Crompton M (2008). Evaluating cytochrome c diffusion in the intermembrane spaces of mitochondria during cytochrome c release. Journal of Cell Science, 121(5), 618 - 625. doi:10.1242/jcs.021303

    2005

    • Capano M, Crompton M (2005). Bax translocates to mitochondria of heart cells during simulated ischaemia; involvement of AMP-activated and p38 mitogen activated protein kinases. Biochemical Journal, 395, 57 - 64. doi:10.1042/BJ20051654

    2004

    • Brustovetskty N, Brustovetsky T, Park KJ, Capano M, Crompton M, Dubinsky JM (2004). Increased susceptibilty of striated mitochondria to the calcium-induced permeability transition.
    • Crompton M (2004). Mitochondria and aging: a role for the permeability transition?. Aging Cell, 3(1), 3 - 6.
    • Li Y, Johnson N, Capano M, Edwards M, Crompton M (2004). Cyclophilin-D promotes the mitochondrial permeability transition but has opposite effects on apoptosis and necrosis.. Biochemical Journal, 383, 101 - 109. doi:10.1042/BJ20040669

    2003

    • Brustovetsky N, Brustovetsky T, Purl KJ, Capano M, Crompton M, Dubinsky JM (2003). Increased susceptibility of striatal mitochondria to calcium-induced permeability transition. Journal of Neuroscience, 23(12), 4858 - 4867.
    • Crompton M (2003). On the involvement of mitochondrial intermembrane junctional complexes in apoptosis. Current Medicinal Chemistry, 10(16), 1473 - 1484.

    2002

    • Capano M, Virji S, Crompton M (2002). Cyclophilin a is involved in excitotoxin induced caspase activation in rat neuronal B50 cells.. Biochemical Journal, 363, 29 - 36.
    • Crompton M, Barksby E, Johnson N, Capano M (2002). Mitochondrial intermembrane junctional complexes and their involvement in cell death. Biochimie, 84, 143 - 152. doi:10.1016/S0300-9084(02)01368-8
    • Capano M, Crompton M (2002). Biphasic translocation of Bax to mitochondria. Biochemical Journal, 367, 169 - 178. doi:10.1042/BJ20020805

    2000

    • Crompton M (2000). Mitochondrial intermembrane junctional complexes and their role in cell death. The Journal of Physiology, 529, 11 - 21.
    • Crompton M (2000). Bax, Bid and the permeabilization of the mitochondrial outer membrane in apoptosis. Current Opinion in Cell Biology, 12(4), 414 - 419.
    • Crompton M (2000). Mitochondrial intermembrane junctional complexes and their role in cell death. doi:10.1111/j.1469-7793.2000.00011.x

    1999

    • Crompton M (1999). The mitochondrial permeability transition pore and its role in cell death.. The Biochemical journal, 341, - .
    • Crompton M, Virji S, Johnson N, Doyle V, Ward JM (1999). The mitochondrial permeability transition pore. Biochemical Society Symposium, 66, 167 - 179.
    • Crompton M (1999). The mitochondrial permeability transition pore and its role in cell death. Biochemical Journal, 341, 233 - 249.
    • Doyle V, Virji S, Crompton M (1999). Evidence that cyclophilin-A protects cells against oxidative stress. Biochemical Journal, 341, 127 - 132.
    • Johnson N, Khan A, Virji S, Ward JM, Crompton M (1999). Import and processing of heart mitochondrial cyclophilin D. European Journal of Biochemistry, 263(2), 353 - 359.
    • Johnson N, Khan A, Virji S, Ward JM, Crompton M (1999). Import and processing of heart mitochondrial cyclophilin D. European Journal of Biochemistry, 263(2), 353 - 359. doi:10.1046/j.1432-1327.1999.00490.x

    1998

    • Duchen MR, Leyssens A, Crompton M (1998). Transient Mitochondrial Depolarizations Reflect Focal Sarcoplasmic Reticular Calcium Release in Single Rat Cardiomyocytes. The Journal of Cell Biology, 142(4), 975 - 988.
    • Johnson N, Virji S, Ward JM, Crompton M (1998). 30 Mitochondrial import of cyclophilin-D. Biochemical Society Transactions, 26(4), - .
    • Doyle V, Virji S, Crompton M (1998). Suppression of cyclophilin-A activity in rat cardiomyocytes. Biochemical Society Transactions, 26, - .
    • Crompton M, Virji S, Doyle V, Johnson N, Ward JM (1998). The nature of a cyclophilin D regulated mitochondrial pore.
    • Duchen MR, Leyssens A, Crompton M (1998). Transient mitochondrial depolarisations in response to focal SR calcium release in single rat cardiomyocytes. The Journal of Cell Biology, 142, 975 - 988.
    • Johnson N, Virji S, Ward JM, Crompton M (1998). Mitochondrial import of cyclophilin-D. Biochemical Society Transactions, 26, - .
    • Crompton M, Virji S, Ward JM (1998). Cyclophilin-D binding proteins. Biochemical Society Transactions, 26, - .
    • Crompton M, Virji S, Ward JM (1998). Cyclophilin-D binds strongly to complexes of the voltage dependent anion channel and the adenine nucleotide translocase to form the permeability transition pore. European Journal of Biochemistry, 258, 729 - 735.

    1996

    • Leyssens A, Nowicky AV, Patterson L, Crompton M, Duchen MR (1996). The relationship between mitochondrial state, ATP hydrolysis, [Mg2+]i and [Ca2+]i studied in isolated rat cardiomyocytes.. J Physiol, 496 ( Pt 1), 111 - 128.
    • Leyssens A, Crompton M, Duchen MR (1996). A role of the mitochondrial permeability transition pore in cell injury by reactive oxygen species in isolated rat cardiomyocytes.
    • Tanveer A, Virji S, Andreeva L, Totty NF, Hsuan JJ, Ward JM, Crompton M (1996). Involvement of cyclophilin D in the activation of a mitochondrial pore by Ca2+ and oxidant stress. European Journal of Biochemistry, 238(1), 166 - 172. doi:10.1111/j.1432-1033.1996.0166q.x

    1995

    • Andreeva L, Tanveer A, Crompton M (1995). Evidence for the involvement of a membrane-associated cyclosporin-A-binding protein in the Ca(2+)-activated inner membrane pore of heart mitochondria.. Eur J Biochem, 230(3), 1125 - 1132.
    • Leyssens A, Anderson M, Craske M, Rastoghi R, Crompton M, Duchen MR (1995). Transient depolarizations of mitochondria localized to discrete areas of single rat cardiomyocytes caused by free radicals and local calcium release.
    • Crompton M, Andreeva L, Tanveer A, Leyssens A (1995). The nature of the cyclosporin A binding component of the mitochondrial Ca2+ dependent pore. In Palmieri F (Ed.), Progress in cell research (pp. 125 - 128). : Elsevier.
    • Leyssens A, Nowicky AV, Patterson L, Crompton M, Duchen MR (1995). Changes in intracellular magnesium and ATP regulated K+ channel activity with changing metabolic state in isolated rat cardiomyocytes.

    1994

    • Crompton M, Andreeva L (1994). On the interactions of Ca2+ and cyclosporin A with a mitochondrial inner membrane pore: a study using cobaltammine complex inhibitors of the Ca2+ uniporter.. Biochem J, 302 ( Pt 1), 181 - 185.
    • Andreeva L, Crompton M (1994). An ADP-sensitive cyclosporin-A-binding protein in rat liver mitochondria.. Eur J Biochem, 221(1), 261 - 268.

    1993

    • Crompton M, Andreeva L (1993). On the involvement of a mitochondrial pore in reperfusion injury.. Basic Res Cardiol, 88(5), 513 - 523.
    • Duchen MR, McGuinness O, Brown LA, Crompton M (1993). On the involvement of a cyclosporin A sensitive mitochondrial pore in myocardial reperfusion injury.. Cardiovasc Res, 27(10), 1790 - 1794.
    • DUCHEN MR, CROMPTON M, PEUCHEN S, NOWICKY AV (1993). THE USE OF A CARBOCYANINE DYE, JC-1, TO MONITOR CHANGES OF MITOCHONDRIAL POTENTIAL IN ISOLATED MAMMALIAN-CELLS. J PHYSIOL-LONDON, 473, P7 - P7.

    1992

    • Crompton M, McGuinness O, Nazareth W, Brown L, Duchen MR (1992). On the involvement of a cyclosporin A sensitive mitochondrial pore in myocardial reperfusion injury.
    • Crompton M, McGuinness O, Nazareth W (1992). The involvement of cyclosporin A binding proteins in regulating and uncoupling mitochondrial energy transduction.. Biochim Biophys Acta, 1101(2), 214 - 217.

    1991

    • Nazareth W, Yafei N, Crompton M (1991). Inhibition of anoxia-induced injury in heart myocytes by cyclosporin A.. J Mol Cell Cardiol, 23(12), 1351 - 1354.
    • Brown GC, Crompton M, Wray S (1991). Cytochrome oxidase content of rat brain during development.. Biochim Biophys Acta, 1057(2), 273 - 275.
    • McCormack JG, Crompton M (1991). The role and study of mammalian mitochondrial Ca2+ transport and matrix Ca2+. In McCormack JG, Cobbold PH (Ed.), Cellular calcium. A practical approach (pp. 345 - 382). : IRL press.

    1990

    • Crompton M, Costi A (1990). A heart mitochondrial Ca2(+)-dependent pore of possible relevance to re-perfusion-induced injury. Evidence that ADP facilitates pore interconversion between the closed and open states.. Biochem J, 266(1), 33 - 39.
    • Yafei N, Belin J, Smith T, Crompton M (1990). Cyclosporin and mitochondrial phospholipid degradation.. Biochem Soc Trans, 18(5), 884 - 885.
    • McGuinness O, Crompton M (1990). Cyclosporin and mitochondrial dysfunction.. Biochem Soc Trans, 18(5), 883 - 884.
    • McGuinness O, Yafei N, Costi A, Crompton M (1990). The presence of two classes of high-affinity cyclosporin A binding sites in mitochondria. Evidence that the minor component is involved in the opening of an inner-membrane Ca(2+)-dependent pore.. Eur J Biochem, 194(2), 671 - 679.
    • Crompton M (1990). The role of Ca2+ in the function and dysfunction of heart mitochondria. In Langer G (Ed.), Calcium and the heart (pp. 167 - 198). : Raven Press.
    • Crompton M (1990). The role of mitochondria in intracellular calcium regulation. In Bronner F (Ed.), Intracellular calcium regulation (pp. 181 - 210). : Wiley-Liss.

    1989

    • Crompton M (1989). Pulsed flow measurements of a Ca2+-activated pore in mitochondria. In (Ed.), Biochemical approaches to cellular calcium. methodological surveys in biochemistry and analysis (pp. 357 - 364). : Royal Society of Chemistry.

    1988

    • Crompton M (1988). The effect of ruthenium red and other agents on mitochondrial calcium metabolism. In (Ed.), Calcium in drug action. handbook of experimental pharmacology (pp. 185 - 194). : Springer-Verlag.
    • Crompton M, Costi A (1988). Kinetic evidence for a heart mitochondrial pore activated by Ca2+, inorganic phosphate and oxidative stress. A potential mechanism for mitochondrial dysfunction during cellular Ca2+ overload.. Eur J Biochem, 178(2), 489 - 501.
    • Crompton M, Ellinger H, Costi A (1988). Inhibition by cyclosporin A of a Ca2+-dependent pore in heart mitochondria activated by inorganic phosphate and oxidative stress.. Biochem J, 255(1), 357 - 360.

    1987

    • Crompton M, Costi A, Hayat L (1987). Evidence for the presence of a reversible Ca2+-dependent pore activated by oxidative stress in heart mitochondria.. Biochem J, 245(3), 915 - 918.
    • Hayat LH, Crompton M (1987). The effects of Mg2+ and adenine nucleotides on the sensitivity of the heart mitochondrial Na+-Ca2+ carrier to extramitochondrial Ca2+. A study using arsenazo III-loaded mitochondria.. Biochem J, 244(3), 533 - 538.
    • Crompton M, Costi A, Hayat L, Al Nasser I (1987). A reversible Ca2+-dependent pore activated by oxidative stress in mitochondria.
    • Goldstone TP, Roos I, Crompton M (1987). Effects of adrenergic agonists and mitochondrial energy state on the Ca transport systems of mitochondria. Biochemistry, 26(1), 246 - 254.

    1986

    • Goldstone TP, Crompton M (1986). The beta-adrenergic activation of the Na+-Ca2+ carrier in rat liver mitochondria.
    • Al-Nasser I, Crompton M (1986). The entrapment of the Ca indicator arsenazo III in the matrix space of rat liver mitochondria by permeabilization and resealing. Na-dependent and -independent effluxes of Ca in arsenazo III-loaded mitochondria. Biochemical Journal, 239(1), 31 - 40.
    • Al-Nasser I, Crompton M (1986). The reversible Ca-induced permeabilization of rat liver mitochondria. Biochemical Journal, 239(1), 19 - 29.
    • Crompton M, Goldstone TP, Al Nasser I (1986). The regulation of mitochondrial calcium. In Bader H, Gietzen K, Rosenthal J, Rudel R, Wolf HU (Ed.), Intracellular Calcium regulation (pp. 67 - 78). : Manchester Univ Press.
    • Crompton M, Goldstone TP (1986). The regulation of mitochondrial calcium by glucagon and adrenergic agonists. In Kraus-Friedmann N (Ed.), Hormonal control of gluconeogenesis (pp. 61 - 70). : CRC Press.
    • Crompton M, Goldstone TP (1986). The involvement of calcium in the stimulation of respiration in isolated rat hepatocytes by adrenergic agonists and glucagon. FEBS Letters, 204(2), 198 - 202.

    1985

    • Crompton M (1985). The regulation of mitochondrial calcium in heart. In (Ed.), Current topics in membranes and transport (pp. 231 - 276). : Academic Press.
    • Crompton M, Roos I (1985). On the hormonal control of heart mitochondrial Ca. Biochemical Society Transactions, 13(4), 667 - 669.
    • Crompton M (1985). The Regulation of Mitochondrial Calcium Transport in Heart. Current Topics in Membranes and Transport, 25(C), 231 - 276. doi:10.1016/S0070-2161(08)60769-8
    • Hayat LH, Crompton M (1985). Ca-dependent inhibition by trifluoperazine of the Na-Ca carrier in mitoplasts derived from heart mitochondria. FEBS Letters, 182(2), 281 - 286.
    • Crompton M, Goldstone TP (1985). The hormonal regulation of mitochondrial calcium. In Quagliariello E (Ed.), Achievements and perspectives in mitochondrial research (pp. 489 - 497). : Elsevier.
    • Crompton M (1985). The calcium carriers of mitochondria. In (Ed.), The enzymes of biological membranes (pp. 249 - 286). : Plenum.

    1984

    • Crompton M, Goldstone TP, Al Nasser I (1984). The regulation of mitochondrial calcium.

    1983

    • Kessar P, Crompton M (1983). The sequestration of Ca by mitochondria in rat heart cells. Cell Calcium, 4(4), 295 - 305.
    • Crompton M, Kessar P, Al Nasser I (1983). The α-adrenergic-mediated activation of the cardiac mitochondrial Ca uniporter and its role in the control of intramitochondrial Ca in vivo. Biochemical Journal, 216(2), 333 - 342.
    • Goldstone TP, Duddridge RJ, Crompton M (1983). The activation of Na+-dependent efflux of Ca2+ from liver mitochondria by glucagon and beta-adrenergic agonists. Biochemical Journal, 210, 463 - 472.
    • Goldstone TP, Crompton M (1983). Hormonal regulation of Ca2+ efflux from mitochondria.

    1982

    • Crompton M, Hayat LH, Goldstone TP, Kessar P (1982). The regulation of the sodium-calcium cycle in heart and liver mitochondria.
    • Hayat LH, Crompton M (1982). Evidence for the existence of regulatory sites for Ca2+ on the Na+/Ca2+ carrier of cardiac mitochondria. Biochemical Journal, 202, 509 - 518.
    • Goldstone TP, Crompton M (1982). Evidence for beta-adrenergic activation of Na+-dependent efflux of Ca2+ from isolated liver mitochondria. Biochemical Journal, 204, 369 - 371.

    1981

    • Panfili E, Crompton M, Sottocasa GL (1981). Immunochemical evidence of the independence of the Ca/Na antiporter and electrophoretic Ca uniporter in heart mitochondria. FEBS Letters, 123(1), 30 - 32.
    • Kessar P, Crompton M (1981). The alpha-adrenergic mediated activation of Ca2+ influx into cardiac mitochondria. Biochemical Journal, 200, 379 - 388.
    • Kessar P, Crompton M (1981). The alpha-adrenergic activation of the Ca2+ uniporter of cardiac mitochondria.
    • Crompton M, Kessar P (1981). The activation of the calcium uniporter of cardiac mitochondria by alpha-adrenergic agonists. In Palmieri F (Ed.), Vectorial reactions in electron and ion transport in mitochondria and bacteria (pp. 261 - 264). : Elsevier.

    1980

    • Carafoli E, Crompton M, Caroni P, Schwerzmann K, Roos I (1980). The cycling of calcium across the inner mitochondrial membrane. In (Ed.), Frontiers of bioorganic chemistry and molecular biology (pp. 405 - 416). : Pergamon.
    • Nicholls DG, Crompton M (1980). Mitochondrial calcium transport. FEBS Letters, 111, 261 - 268.
    • Crompton M (1980). The sodium ion/calcium ion cycle of cardiac mitochondria.
    • Roos I, Crompton M, Carafoli E (1980). The role of inorganic phosphate in the release of calcium from rat liver mitochondria. European Journal of Biochemistry, 110, 319 - 325.
    • Crompton M, Heid I, Carfoli E (1980). The activation by potassium of the sodium-calcium carrier of cardiac mitochondria. FEBS Letters, 115(2), 257 - 259.

    1979

    • Crompton M, Carafoli E (1979). A look at Ca efflux. Trends in Biochemical Sciences, 4(2), - .
    • Crompton M, Heid I, Baschera C, Carafoli E (1979). The resolution of calcium fluxes in heart and liver mitochondria using the lanthanide series. FEBS Letters, 104(2), 352 - 354.
    • Crompton M, Chappell JB (1979). Anion transport in mitochondria. In Carafoli E, Semenza G (Ed.), Membrane biochemistry: a laboratory manual on transport and bioenergetics (pp. 98 - 102). : Springer-Verlag.
    • Chappell JB, Crompton M (1979). Determination of the membrane potential and pH difference across the mitochondrial inner membrane. In Carafoli E, Semenza G (Ed.), Membrane biochemistry: a laboratory manual on transport and bionergetics (pp. 92 - 97). : Springer-Verlag.
    • Crompton M, Carafoli E (1979). The measurement of calcium movements in miotchondria. In Fleischer S, Packer L (Ed.), Methods in Enzymology (pp. 338 - 352). : Academic Press.
    • Carafoli E, Crompton M (1979). Mechanisms for the transport of calcium in mitochondria. In Quagliariello E, Palmieri F, Papa S, Klingenberg M (Ed.), Function and molecular aspects of biomembrane transport (pp. 157 - 169). : Elsevier.
    • Gazzotti P, Malmstrom K, Crompton M (1979). Preparation and assay of animal mitochondria and submitochondrial particles. In Carafoli E, Semenza G (Ed.), Membrane biochemistry: a laboratory manual on transport and bioenergetics (pp. 62 - 76). : Springer-Verlag.
    • Crompton M, Carafoli E (1979). The application of calcium-selective electrodes and inhibitor-stop techniques to the resolution of calcium fluxes in mitochondria. In Ashley CC, Campbell AK (Ed.), Detection and measurement of free calcium in cells (pp. 373 - 382). : Elsevier.
    • Crompton M, Sigel E, Carafoli E (1979). Distinguishing the two calcium carriers of mitochondria. In Quagliariello E, Palmieri F, Papa S, Klingenberg M (Ed.), Function and molecular aspects of biomembrane transport (pp. 171 - 174). : Elsevier.

    1978

    • Carafoli E, Crompton M (1978). The regulation of intracellular calcium by mitochondria. Annals of the new york academy of sciences, 307, 269 - 284.
    • CROMPTON M, HEDIGER M, CARAFOLI E (1978). EFFECT OF INORGANIC-PHOSPHATE ON CALCIUM INFLUX INTO RAT-HEART MITOCHONDRIA. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 80(3), 540 - 546. doi:10.1016/0006-291X(78)91602-9
    • CROMPTON M, MOSER R, LUDI H, CARAFOLI E (1978). INTERRELATIONS BETWEEN TRANSPORT OF SODIUM AND CALCIUM IN MITOCHONDRIA OF VARIOUS MAMMALIAN-TISSUES. EUROPEAN JOURNAL OF BIOCHEMISTRY, 82(1), 25 - 31. doi:10.1111/j.1432-1033.1978.tb11993.x
    • Carafoli E, Crompton M (1978). The regulation of intracellular calcium. Current Topics in Membranes and Transport, 10(C), 151 - 216. doi:10.1016/S0070-2161(08)60835-7
    • Crompton M, Heid I (1978). The cycling of calcium, sodium and protons across the inner membrane of cardiac mitochondria. European Journal of Biochemistry, 91, 599 - 608.
    • Roos I, Crompton M, Carafoli E (1978). The effect of phosphoenolpyruvate on the retention of calcium by liver mitochondria. FEBS Letters, 94(2), 418 - 421. doi:10.1016/0014-5793(78)80990-9
    • Carafoli E, Scherzmann K, Roos I, Crompton M (1978). Proetins in mitochondrial calcium transport. In Blauer G, Sund H (Ed.), Transport by proteins (pp. 171 - 186). : de Gruyter.

    1977

    • Carafoli E, Crompton M, Malmstrom K, Sigel E, Salzmann M, Chiesi M, Affolter H (1977). Mitochondrial calcium transport and intracellular calcium homeostasis.
    • CROMPTON M, KUNZI M, CARAFOLI E (1977). CALCIUM-INDUCED AND SODIUM-INDUCED EFFLUXES OF CALCIUM FROM HEART-MITOCHONDRIA - EVIDENCE FOR A SODIUM-CALCIUM CARRIER. EUROPEAN JOURNAL OF BIOCHEMISTRY, 79(2), 549 - 558. doi:10.1111/j.1432-1033.1977.tb11839.x
    • Carafoli E, Crompton M, Malmstrom K (1977). The reversibility of mitochondrial calcium transport and its physiological implications.
    • Roos I, Crompton M, Carafoli E (1977). The effect of phosphoenolpyruvate on the retention of calcium by liver mitochondria.
    • Crompton M, Carafoli E (1977). The carriers responsible for the distribution of calcium between cardiac mitochondria and cytoplasm.

    1976

    • CROMPTON M, SIGEL E, SALZMANN M, CARAFOLI E (1976). KINETIC STUDY OF ENERGY-LINKED INFLUX OF CA2+ INTO HEART-MITOCHONDRIA. EUROPEAN JOURNAL OF BIOCHEMISTRY, 69(2), 429 - 434. doi:10.1111/j.1432-1033.1976.tb10927.x
    • Carafoli E, Crompton M (1976). Binding proteins and membrane transport. In (Ed.), The enzymes of biological membranes (pp. 193 - 219). : Plenum.
    • Carafoli E, Malmstrom K, Sigel E, Crompton M (1976). The regulation of intracellular calcium. Clinical Endocrinology, 5, 49s - 59s.
    • CROMPTON M, CAPANO M, CARAFOLI E (1976). RESPIRATION-DEPENDENT EFFLUX OF MAGNESIUM-IONS FROM HEART-MITOCHONDRIA. BIOCHEMICAL JOURNAL, 154(3), 735 - 742.
    • CROMPTON M, CAPANO M, CARAFOLI E (1976). SODIUM-INDUCED EFFLUX OF CALCIUM FROM HEART-MITOCHONDRIA - POSSIBLE MECHANISM FOR REGULATION OF MITOCHONDRIAL CALCIUM. EUROPEAN JOURNAL OF BIOCHEMISTRY, 69(2), 453 - 462. doi:10.1111/j.1432-1033.1976.tb10930.x
    • Carafoli E, Crompton M (1976). Calcium ions and mitochondria. In (Ed.), Calcium in biological systems (pp. 89 - 115). : Cambridge University Press.

    1975

    • Carafoli E, Malmstrom K, Capano M, Sigel E, Crompton M (1975). Mitochondria and the regulation of cell calcium.
    • Crompton M, Palmieri F, Capano M, Quagliariello E (1975). A kinetic study of sulphate transport in rat liver mitochondria. Biochemical Journal, 146, 667 - 673.

    1974

    • Crompton M, Palmieri F, Capano M, Quagliariello E (1974). Mitochondrial sulphate and sulphite transport. In (Ed.), Biomembranes: Architecture, Biogenesis, Bioenergetics and Differentiation (pp. 213 - 220). : Academic Press.
    • Crompton M, Palmieri F, Capano M, Quagiariello E (1974). The transport of thiosulphate in rat liver mitochondria. FEBS Letters, 46, 247 - 250.

    1973

    • Crompton M, McGivan JD, Chappell JB (1973). The intramitochondrial location of the glutaminase isoenzymes of pig kidney. Biochemical Journal, 132, 27 - 34.
    • Crompton M, Palmieri F, Capano M, Quagliariello E (1973). The transport of sulphate and sulphite in rat liver mitochondria. Biochemical Journal, 142, 127 - 137.
    • Crompton M, Chappell JB (1973). Transport of glutamine and glutamate in kidney mitochondria in relation to glutamine deamidation. Biochemical Journal, 132, 35 - 46.
    • Crompton M, Chappell JB, McGivan JD (1973). Mitochondrial glutamine and glutamate transport during renal gluconeogenesis. Atti del Seminario di Studi Biologici, 5, 239 - 252.
    • McGivan JD, Bradford N, Crompton M, Chappell JB (1973). Effect of Leucine on the nitrogen metabolism of isolated rat liver mitochondria. Biochemical Journal, 134, 209 - 215.
    • Raison JK, Laties GG, Crompton M (1973). The role of state 4 electron transport in the activation of state 3 respiration in potato mitochondria. Journal of Bioenergetics and Biomembranes, 4, 409 - 422.

    1972

    • Chappell JB, McGivan JD, Crompton M (1972). The anion transporting systems of mitochondria and their biological significance.

    1971

    • Crompton M, Laties GG (1971). The regulatory function of potato pyruvate dehydrogenase. Archives of Biochemistry and Biophysics, 143, 143 - 150.

    1969

    • Crompton M, Polakis SE (1969). The labelling of tissue components during the pharate adult life of Lucilia cuprina, after injection of U-C-glucose. Journal of Insect Physiology, 15(8), 1323 - 1329.
    • Crompton M, Birt LM (1969). Changes in the in vitro activity of glycolytic enzymes during metamorphosis of the blowfly, Lucilia cuprina. Journal of Insect Physiology, 15(7), 1119 - 1127.

    1967

    • Crompton M, Birt LM (1967). Changes in the amounts of carbohydrates, phosphagen, and related compounds during the metamorphosis of the blowfly, Lucilia cuprina. Journal of Insect Physiology, 13(10), 1575 - 1592.