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Prof Chris Boshoff

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Personal Profile

Name: Chris Boshoff Email: c.boshoff@ucl.ac.uk
Title: Prof Tel: 0044 20 7679 6549
Department: Research Department of Cancer Biology Fax: 0044 207 67 96817
Position: Honorary Professor Address: UCL Cancer Institute, Paul O'Gorman Building, Huntley Street, London, WC1E 6BT
Research Domain: Cancer, Personalised Medicine Web Page: Personal Web Page

Profile

Research Description

Dr Boshoff is a highly cited clinician scientist, his papers have been cited over 10,000 times by other investigators in the field, and he has published in all the top international scientific and medical Journals including Nature, Science, Nature Medicine, Nature Genetics, Nature Cell Biology, Proceedings of the National Academy of Sciences USA, The Lancet, Lancet Oncology and The New England Journal of Medicine.


Research Activities

Effect of Tumour Biology on Therapeutic Response

Experimental cancer therapeutics

Host and Pathogen Genomics

Humoral immunity to HIV, emerging infections

Regulation and targeting of the hypoxia inducible factor (HIF) pathway

Transcription and chromatin

Understanding the role of stem cells in cancer development

Education Description

.  TEACHING ACTIVITY

 

Facilitated the establishment of an MSc Cancer Course, Cancer Institute PhD Programme and Undergraduate Cancer Teaching.


Regular teacher at:

MSc courses at UCL for Oncology, Molecular Medicine, Urology and Virology.

MSc courses at the London School of Hygiene and Tropical Medicine and at Institute for Cancer Research.

Cancer Introduction and Cancer Biology Lectures to UCL Medical Students.

UCL Collaborators

Prof Barbara Pedley; Prof Daniel Hochhauser; Prof David Gems; Prof Hans Stauss; Dr Ariberto Fassati; Prof Quentin Pankhurst; Prof Peter Coveney; Dr Laurence Lovat; Dr Richard Jenner; Prof Tony Segal; Prof Ivan Gout; Prof Robin Weiss; Dr John Bridgewater; Prof Tim Meyer; Prof Patrick Maxwell; Prof Michael Duchen; Prof Margaret Ashcroft; Prof Mike Ehrenstein; Prof Steve Wilson; Prof Paul Beard; Prof Samuel Janes; Prof Stephen Caddick; Prof Mark Lythgoe; Dr Erik Arstad; Prof Deenan Pillay; Dr Yasu Takeuchi; Prof John Hartley; Prof Greg Towers; Prof Christine Orengo; Dr Adil Butt

External Collaborators

Publications

    2013

    • Cancian L, Hansen A, Boshoff C (2013). Cellular origin of Kaposi's sarcoma and Kaposi's sarcoma-associated herpesvirus-induced cell reprogramming.. Trends Cell Biol, , - . doi:10.1016/j.tcb.2013.04.001
    • Lechner M, Fenton T, West J, Wilson G, Feber A, Henderson S, Thirlwell C, Dibra HK, Jay A, Butcher L, Chakravarthy AR, Gratrix F, Patel N, Vaz F, O'Flynn P, Kalavrezos N, Teschendorff AE, Boshoff C, Beck S (2013). Identification and functional validation of HPV-mediated hypermethylation in head and neck squamous cell carcinoma.. Genome Med, 5(2), 15 - . doi:10.1186/gm419
    • Rodriguez R, Tornin J, Suarez C, Astudillo A, Rubio R, Yauk C, Williams A, Rosu-Myles M, Funes JM, Boshoff C, Menendez P (2013). Expression of FUS-CHOP Fusion Protein in Immortalized/Transformed Human Mesenchymal Stem Cells Drives Mixoid Liposarcoma Formation.. Stem Cells, , - . doi:10.1002/stem.1472
    • Lechner M, Frampton G, Fenton T, Feber A, Palmer G, Jay A, Pillay N, Forster MD, Cronin MT, Lipson D, Miller VA, Henderson S, Vaz F, O'Flynn P, Kalavrezos N, Yelenski R, Beck S, Stephens PJ, Boshoff C (2013). Targeted next-generation sequencing of head and neck squamous cell carcinoma identifies novel genetic alterations in HPV+ and HPV- tumors. Genome Medicine: medicine in the post-genomic era, , - .
    • Yogev O, Boshoff C (2013). Redefining KSHV latency.. Cell Host Microbe, 13(4), 373 - 374. doi:10.1016/j.chom.2013.04.003
    • Wilson GA, Lechner M, Köferle A, Carén H, Butcher LM, Feber A, Fenton T, Jay A, Boshoff C, Beck S (2013). Integrated virus-host methylome analysis in head and neck squamous cell carcinoma.. Epigenetics, 8(9), - .
    • Nikitenko LL, Shimosawa T, Henderson S, Mäkinen T, Shimosawa H, Qureshi U, Pedley RB, Rees MC, Fujita T, Boshoff C (2013). Adrenomedullin haploinsufficiency predisposes to secondary lymphedema.. J Invest Dermatol, 133(7), 1768 - 1776. doi:10.1038/jid.2013.47

    2012

    • Gooding M, Tudzarova S, Worthington RJ, Kingsbury SR, Rebstock AS, Dube H, Simone MI, Visintin C, Lagos D, Quesada JM, Laman H, Boshoff C, Williams GH, Stoeber K, Selwood DL (2012). Exploring the interaction between siRNA and the SMoC biomolecule transporters: implications for small molecule-mediated delivery of siRNA.. Chem Biol Drug Des, 79(1), 9 - 21. doi:10.1111/j.1747-0285.2011.01249.x
    • Boshoff C (2012). Ephrin receptor: a door to KSHV infection.. Nat Med, 18(6), 861 - 863. doi:10.1038/nm.2803
    • Bridge G, Monteiro R, Henderson S, Emuss V, Lagos D, Georgopoulou D, Patient R, Boshoff C, Boshoff C (2012). The microRNA-30 family targets DLL4 to modulate endothelial cell behavior during angiogenesis. Blood, , - .
    • Lee SM, Khan I, Upadhyay S, Lewanski C, Falk S, Skailes G, Marshall E, Woll PJ, Hatton M, Lal R, Jones R, Toy E, Chao D, Middleton G, Bulley S, Ngai Y, Rudd R, Hackshaw A, Boshoff C (2012). First-line erlotinib in patients with advanced non-small-cell lung cancer unsuitable for chemotherapy (TOPICAL): a double-blind, placebo-controlled, phase 3 trial.. Lancet Oncol, 13(11), 1161 - 1170. doi:10.1016/S1470-2045(12)70412-6
    • Westrop SJ, Lagos D, Boshoff C, Bower M, Imami N (2012). African ancestry and innate immunity contribute to the incidence of multicentric Castleman's disease in HIV-1/Kaposi's sarcoma herpesvirus-coinfected individuals. FUTURE VIROLOGY, 7(7), 729 - 734. doi:10.2217/FVL.12.54
    • Lee S, Upadhyay S, Lewanski C, Falk S, Skailes G, Marshall E, Ngai Y, Rudd R, Hackshaw A, Boshoff C (2012). TOPICAL: RANDOMIZED PHASE III TRIAL OF ERLOTINIB COMPARED WITH PLACEBO IN PATIENTS WITH ADVANCED NON-SMALL CELL LUNG CANCER (NSCLC) UNSUITABLE FOR FIRST-LINE CHEMOTHERAPY: UPDATED ANALYSIS.

    2011

    • Cheng F, Pekkonen P, Laurinavicius S, Sugiyama N, Henderson S, Günther T, Rantanen V, Kaivanto E, Aavikko M, Sarek G, Hautaniemi S, Biberfeld P, Aaltonen L, Grundhoff A, Boshoff C, Alitalo K, Lehti K, Ojala PM (2011). KSHV-initiated notch activation leads to membrane-type-1 matrix metalloproteinase-dependent lymphatic endothelial-to-mesenchymal transition.. Cell Host Microbe, 10(6), 577 - 590. doi:10.1016/j.chom.2011.10.011
    • He M, Bakken T, Kassimova A, Boshoff C, Philpott N, Cannon ML (2011). Focal adhesion kinase is required for KSHV vGPCR signaling.. Mol Carcinog, , - . doi:10.1002/mc.20790
    • Yi JM, Dhir M, Van Neste L, Downing SR, Jeschke J, Glöckner SC, de Freitas Calmon M, Hooker CM, Funes JM, Boshoff C, Smits KM, van Engeland M, Weijenberg MP, Iacobuzio-Donahue CA, Herman JG, Schuebel KE, Baylin SB, Ahuja N (2011). Genomic and epigenomic integration identifies a prognostic signature in colon cancer.. Clin Cancer Res, 17(6), 1535 - 1545. doi:10.1158/1078-0432.CCR-10-2509
    • Boshoff C (2011). Unraveling virus-induced lymphomagenesis.. J Clin Invest, 121(3), 838 - 841. doi:10.1172/JCI46499

    2010

    • Lagos D, Pollara G, Henderson S, Gratrix F, Fabani M, Milne RS, Gotch F, Boshoff C (2010). miR-132 regulates antiviral innate immunity through suppression of the p300 transcriptional co-activator.. Nat Cell Biol, 12(5), 513 - 519. doi:10.1038/ncb2054
    • Lechner M, Boshoff C, Beck S (2010). Cancer Epigenome. EPIGENETICS AND CANCER, PT A, 70, 247 - 276. doi:10.1016/S0065-2660(10)70009-2
    • Lechner M, Boshoff C, Beck S (2010). Cancer epigenome.. Adv Genet, 70, 247 - 276. doi:10.1016/B978-0-12-380866-0.60009-5
    • Hansen A, Henderson S, Lagos D, Nikitenko L, Coulter E, Roberts S, Gratrix F, Plaisance K, Renne R, Bower M, Kellam P, Boshoff C (2010). KSHV-encoded miRNAs target MAF to induce endothelial cell reprogramming.. Genes Dev, 24(2), 195 - 205. doi:10.1101/gad.553410
    • Flanagan JM, Cocciardi S, Waddell N, Johnstone CN, Marsh A, Henderson S, Simpson P, da Silva L, kConFab Investigators , Khanna K, Lakhani S, Boshoff C, Chenevix-Trench G (2010). DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status.. Am J Hum Genet, 86(3), 420 - 433. doi:10.1016/j.ajhg.2010.02.008
    • Wild L, Funes JM, Boshoff C, Flanagan JM (2010). In vitro transformation of mesenchymal stem cells induces gradual genomic hypomethylation.. Carcinogenesis, 31(10), 1854 - 1862. doi:10.1093/carcin/bgq080
    • Flanagan J, Kugler S, Waddell N, Johnstone C, Marsh A, Henderson S, Simpson P, da Silva L, Khanna K, Lakhani S, Boshoff C, Chenevix-Trench G (2010). DNA methylome of familial breast cancer identifies distinct profiles defined by mutation status.. Breast Cancer Res, 12 Suppl 1, O4 - . doi:10.1186/bcr2495
    • Mesri EA, Cesarman E, Boshoff C (2010). Kaposi's sarcoma and its associated herpesvirus.. Nat Rev Cancer, 10(10), 707 - 719. doi:10.1038/nrc2888

    2009

    • Flanagan JM, Munoz-Alegre M, Henderson S, Tang T, Sun P, Johnson N, Fletcher O, Dos Santos Silva I, Peto J, Boshoff C, Narod S, Petronis A (2009). Gene-body hypermethylation of ATM in peripheral blood DNA of bilateral breast cancer patients.. Hum Mol Genet, 18(7), 1332 - 1342. doi:10.1093/hmg/ddp033
    • Boshoff C, Posner M (2009). Targeting EGFR in head and neck cancer: a decade of progress.. Nat Clin Pract Oncol, 6(3), 123 - . doi:10.1038/ncponc1328
    • Emuss V, Lagos D, Pizzey A, Gratrix F, Henderson SR, Boshoff C (2009). KSHV manipulates Notch signaling by DLL4 and JAG1 to alter cell cycle genes in lymphatic endothelia.. PLoS Pathog, 5(10), e1000616 - . doi:10.1371/journal.ppat.1000616
    • Flanagan JM, Funes JM, Henderson S, Wild L, Carey N, Boshoff C (2009). Genomics screen in transformed stem cells reveals RNASEH2A, PPAP2C, and ADARB1 as putative anticancer drug targets.. Mol Cancer Ther, 8(1), 249 - 260. doi:10.1158/1535-7163.MCT-08-0636
    • Robey RC, Lagos D, Gratrix F, Henderson S, Matthews NC, Vart RJ, Bower M, Boshoff C, Gotch FM (2009). The CD8 and CD4 T-cell response against Kaposi's sarcoma-associated herpesvirus is skewed towards early and late lytic antigens.. PLoS One, 4(6), e5890 - . doi:10.1371/journal.pone.0005890

    2008

    • Bagnéris C, Ageichik AV, Cronin N, Wallace B, Collins MK, Boshoff C, Waksman G, Barrett T (2008). Crystal structure of a vFlip-IKKgamma complex: insights into viral activation of the IKK signalosome.. Molecular Cell, 30(5), 620 - 631. doi:10.1016/j.molcel.2008.04.029
    • Di Bartolo DL, Cannon M, Liu YF, Renne R, Chadburn A, Boshoff C, Cesarman E (2008). KSHV LANA inhibits TGF-beta signaling through epigenetic silencing of the TGF-beta type II receptor.. Blood, 111(9), 4731 - 4740. doi:10.1182/blood-2007-09-110544
    • Mutalima N, Molyneux E, Jaffe H, Kamiza S, Borgstein E, Mkandawire N, Liomba G, Batumba M, Lagos D, Gratrix F, Boshoff C, Casabonne D, Carpenter LM, Newton R (2008). Associations between Burkitt lymphoma among children in Malawi and infection with HIV, EBV and malaria: results from a case-control study.. PLoS One, 3(6), e2505 - . doi:10.1371/journal.pone.0002505
    • Lagos D, Vart RJ, Gratrix F, Westrop SJ, Emuss V, Wong PP, Robey R, Imami N, Bower M, Gotch F, Boshoff C (2008). Toll-like receptor 4 mediates innate immunity to Kaposi sarcoma herpesvirus.. Cell Host Microbe, 4(5), 470 - 483. doi:10.1016/j.chom.2008.09.012

    2007

    • Lagos D, Trotter MW, Vart RJ, Wang HW, Matthews NC, Hansen A, Flore O, Gotch F, Boshoff C (2007). Kaposi sarcoma herpesvirus-encoded vFLIP and vIRF1 regulate antigen presentation in lymphatic endothelial cells.. Blood, 109(4), 1550 - 1558. doi:10.1182/blood-2006-05-024034
    • Hansen A, Boshoff C, Lagos D (2007). Kaposi sarcoma as a model of oncogenesis and cancer treatment.. Expert Rev Anticancer Ther, 7(2), 211 - 220. doi:10.1586/14737140.7.2.211
    • Okuyama M, Laman H, Kingsbury S, Visintin C, Leo E, Eward KL, Stoeber K, Boshoff C, Williams GH, Selwood DL (2007). Small molecule mimics of an α-helix for rapid and efficient transport of proteins into cells. Nature Methods, 4(2), 153 - 159. doi:10.1038/nmeth997
    • Hansen A, Boshoff C, Lagos D (2007). Kaposi sarcoma as a model of oncogenesis and cancer treatment. Expert Review of Anti-Cancer Therapy, 7(2), 211 - 220.
    • Lagos D, Trotter MWB, Vart RJ, Wang HW, Matthews NC, Hansen A, Flore O, Gotch F, Boshoff C (2007). Kaposi sarcoma herpesvirus-encoded vFLIP and vIRF1 regulate antigen presentation in lymphatic endothelial cells. Blood, 109(4), 1550 - 1558.
    • Okuyama M, Laman H, Kingsbury SR, Visintin C, Leo E, Eward KL, Stoeber K, Boshoff C, Williams GH, Selwood DL (2007). Small-molecule mimics of an alpha-helix for efficient transport of proteins into cells. Nature Methods, 4(2), 153 - 159. doi:10.1038/nmeth997
    • Vart RJ, Nikitenko LL, Leonid L, Lagos D, Trotter MWB, Cannon M, Bourboulia D, Gratrix F, Takeuchi B, C (2007). Kaposi's sarcoma-associated herpesvirus-encoded interleukin-6 and G-protein-coupled receptor regulate angiopoletin-2 expression in lymphatic endothelial cells. Cancer Research, 67(9), 4042 - 4051.
    • Malcles M-H, Wang H-W, Koumi A, Tsai Y-H, Yu M, Godfrey A, Boshoff C (2007). Characterisation of the anti-apoptotic function of survivin-Delta Ex3 during TNF alpha-mediated cell death. British Journal of Cancer, 96(11), 1659 - 1666.
    • Bousdras K, O'Donnell P, Vujovic S, Henderson S, Boshoff C, Flanagan AM (2007). Chondroblastomas but not chondromyxoid fibromas express cytokeratins: an unusual presentation of a chondroblastoma in the metaphyseal cortex of the tibia. HISTOPATHOLOGY, 51(3), 414 - 416. doi:10.1111/j.1365-2559.2007.02777.x
    • O Donnell P, Tirabosco R, Vujovic S, Bartlett W, Briggs TWR, Henderson S, Boshoff C, Flanagan AM (2007). Diagnosing an extra-axial chordoma of the proximal tibia with the help of brachyury, a molecule required for notochordal differentiation. Skeletal radiology, 36, 59 - 65.
    • Funes JM, Quintero M, Henderson S, Martinez D, Qureshi U, Westwood C, Clements MO, Bourboulia D, Pedley RB, Moncada S, others (2007). Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production. Proceedings of the National Academy of Sciences, 104, 6223 - 6228.

    2006

    • Cannon M, Cesarman E, Boshoff C (2006). KSHV G protein-coupled receptor inhibits lytic gene transcription in primary-effusion lymphoma cells via p21-mediated inhibition of Cdk2. BLOOD, 107(1), 277 - 284.
    • Boshoff C (2006). The Biology of Cancer Robert A Weinberg. Nature, 444(549), 796 - 796. doi:10.1038/444549a
    • Nikitenko L, Boshoff C (2006). Endothelial cells and cancer.. Handb Exp Pharmacol, (176 Pt 2), 307 - 334.
    • Lai CS, Boshoff C, Falzon M, Lee SM (2006). Complete response to erlotinib treatment in brain metastases from recurrent NSCLC.. Thorax, 61(1), 91 - . doi:10.1136/thx.2005.052233
    • Clements MO, Godfrey A, Crossley J, Wilson SJ, Takeuchi Y, Boshoff C (2006). Lentiviral manipulation of gene expression in human adult and embryonic stem cells. TISSUE ENGINEERING, 12(7), 1741 - 1751.
    • Markusen JF, Mason C, Hull DA, Town MA, Tabor AB, Clements M, Boshoff CH, Dunnill P (2006). Behavior of adult human mesenchymal stem cells entrapped in alginate-GRGDY beads.. Tissue Engineering, 12(4), 821 - 830. doi:10.1089/ten.2006.12.821
    • Lai CSL, Boshoff C, Falzon M, Lee SM (2006). Complete response to erlotinib treatment in brain metastases from recurrent NSCLC.
    • Vujovic S, Henderson S, Presneau N, Odell E, Jacques TS, Tirabosco R, Boshoff C, Flanagan AM (2006). Brachyury, a crucial regulator of notochordal development, is a novel biomarker for chordomas. The Journal of pathology, 209, 157 - 165.
    • Newton R, Carpenter L, Casabonne D, Beral V, Babiker A, Darbyshire J, Weller I, Weiss R, Kwan A, Bourboulia D, Munoz F, Lagos D, Boshoff C (2006). A prospective study of Kaposi's sarcoma-associated herpesvirus and Epstein-Barr virus in adults with human immunodeficiency virus-1. BRITISH JOURNAL OF CANCER, 94(10), 1504 - 1509. doi:10.1038/sj.bjc.6603100

    2005

    • Laman H, Funes JM, Ye H, Henderson S, Galinanes-Garcia L, Hara E, Knowles P, McDonald N, Boshoff C (2005). Transforming activity of Fbxo7 is mediated specifically through regulation of cyclin D/cdk6.. EMBO J, 24(17), 3104 - 3116. doi:10.1038/sj.emboj.7600775
    • Godfrey A, Anderson WJ, Papanastasiou A, Takeuchi Y, Boshoff C (2005). Inhibiting primary effusion lymphoma, by lentiviral vectors encoding short hairpin RNA. Blood, 105(6), 2510 - 2518. doi:10.1182/blood-2004-08-3052
    • Laman H, Funes JM, Ye H, Henderson S, Galinanes-Garcia L, Hara E, Knowles P, McDonald N, Boshoff C (2005). Transforming activity of Fbxo7 is mediated specifically through regulation of cyclin D/cdk6. The EMBO journal, 24, 3104 - 3116.
    • Lagos D, Bourboulia D, Vart R, Trotter M, Malcles M, Wang HW, Boshoff C (2005). Kaposi sarcoma herpesvirus: Update. RETROVIROLOGY, 2, - . doi:10.1186/1742-4690-2-S1-S40
    • Wang HW, Boshoff C (2005). Linking Kaposi virus to cancer-associated cytokines. , 11(7), 309 - 312.
    • Henderson SR, Guiliano D, Presneau N, McLean S, Frow R, Vujovic S, Anderson J, Sebire N, Whelan J, Athanasou N, others (2005). A molecular map of mesenchymal tumors. Genome biology, 6, 76 - 76.
    • McLean SR, Gana-Weisz M, Hartzoulakis B, Frow R, Whelan J, Selwood D, Boshoff C (2005). Imatinib binding and cKIT inhibition is abrogated by the cKIT kinase domain I missense mutation Val(654)Ala. Molecular Cancer Therapeutics, 4(12), 2008 - 2012.

    2004

    • Wang HW, Trotter MWB, Lagos D, Bourboulia D, Henderson S, Mäkinen T, Elliman S, Flanagan AM, Alitalo K, Boshoff C (2004). Kaposi sarcoma herpesvirus–induced cellular reprogramming contributes to the lymphatic endothelial gene expression in Kaposi sarcoma. Nature genetics, 36, 687 - 693.
    • Sharp TV, Munoz F, Bourboulia D, Presneau N, Darai E, Wang HW, Cannon M, Butcher DN, Nicholson AG, Klein G, Imreh S, Boshoff C (2004). LIM domains-containing protein 1 (LIMD1), a tumor suppressor encoded at chromosome 3p21.3, binds pRB and represses E2F-driven transcription.. Proc Natl Acad Sci U S A, 101(47), 16531 - 16536. doi:10.1073/pnas.0407123101
    • Bourboulia D, Aldam D, Lagos D, Allen E, Williams I, Cornforth D, Copas A, Boshoff C (2004). Short- and long-term effects of highly active antiretroviral therapy on Kaposi sarcoma-associated herpesvirus immune responses and viraemia. AIDS, 18(3), 485 - 493. doi:10.1097/00002030-200402200-00015
    • Bourboulia D, Aldam D, Lagos D, Allen E, Williams I, Cornforth D, Copas A, Boshoff C (2004). Short- and long-term effects of highly active antiretroviral therapy on Kaposi sarcoma-associated herpesvirus immune responses and viraemia.. AIDS, 18(3), 485 - 493.
    • Hamoudi RA, Diss TC, Oksenhendler E, Pan L, Carbone A, Ascoli V, Boshoff C, Isaacson P, Du MQ (2004). Distinct cellular origins of primary effusion lymphoma with and without EBV infection. Leukemia Research, 28(4), 333 - 338.
    • Godfrey A, Anderson J, Papanastasiou A, Takeuchi Y, Boshoff C (2004). Related ArInhibiting primary effusion lymphoma by lentiviral vectors encoding short hairpin RNA.. Blood, , - .
    • Sharp TV, Munoz F, Bourboulia D, Presneau N, Darai E, Wang HW, Cannon M, Butcher DN, Nicholson AG, Klein G, Imreh S, Boshoff C (2004). LIM domains-containing protein 1 (LIMD1), a tumor suppressor encoded at chromosome 3p21.3, binds pRB and represses E2F-driven transcription.. Proceedings of the National Academy of Sciences of the United States of America, 101(47), 16531 - 16536. doi:10.1073/pnas.0407123101
    • Sharp T, Munoz F, Bourboulia D, Presneau N, Darai E, Wang HW, Cannon M, Burcher DN, Nicholson AG, Klein G, Imreh S, Boshoff C (2004). LIMD1, a tumor suppressor at 3p21.3, binds pRb and represses E2F-driven transcription. Proceedings of the National Academy of Sciences of the United States of America, 10, 16531 - 16536. doi:10.1073/pnas.0407123101
    • Adib TR, Henderson S, Perrett C, Hewitt D, Bourmpoulia D, Ledermann J, Boshoff C (2004). Predicting biomarkers for ovarian cancer using gene-expression microarrays. British journal of cancer, 90, 686 - 692.
    • Adib TR, Henderson S, Perrett C, Hewitt D, Bourmpoulia D, Ledermann J, Boshoff C (2004). Predicting biomarkers for ovarian cancer using gene-expression microarrays.. Br J Cancer, 90(3), 686 - 692. doi:10.1038/sj.bjc.6601603

    2003

    • Leonard P, Sharp T, Henderson S, Hewitt D, Pringle J, Sandison A, Goodship A, Whelan J, Boshoff C (2003). Gene expression array profile of human osteosarcoma. British journal of cancer, 89, 2284 - 2288.
    • Jenner RG, Maillard K, Cattini N, Weiss RA, Boshoff C, Wooster R, Kellam P (2003). Kaposi's sarcoma-associated herpes virus-infected primary effusion lymphoma has a plasma cell gene expression profile. Proceedings of the National Academy of Sciences of the United States of America, 100(18), 10399 - 10404. doi:10.1073/pnas.1630810100
    • Newton R, Ziegler J, Bourboulia D, Casabonne D, Beral V, Mbidde E, Carpenter L, Parkin DM, Wabinga H, Mbulaiteye S, Jaffe H, Weiss R, Boshoff C (2003). Infection with Kaposi's sarcoma-associated herpesvirus (KSHV) and human immunodeficiency virus (HIV) in relation to the risk and clinical presentation of Kaposi's sarcoma in Uganda.. Br J Cancer, 89(3), 502 - 504. doi:10.1038/sj.bjc.6601113
    • Newton R, Ziegler J, Ateenyi-Agaba C, Bousarghin L, Casabonne D, Beral V, Mbidde E, Carpenter L, Reeves G, Parkin DM, Wabinga H, Mbulaiteye S, Jaffe H, Bourboulia D, Boshoff C, Touze A, Coursaget P, Uganda Kaposi's Sarcoma Study Grp (2003). The epidemiology of conjunctival squamous cell carcinoma in Uganda (vol 87, pg 301, 2002). BRIT J CANCER, 89(2), 423 - 423. doi:10.1038/sj.bjc.6601128
    • Stebbing J, Bourboulia D, Johnson M, Henderson S, Williams I, Wilder N, Tyrer M, Youle M, Imami N, Kobu T, Kuon W, Sieper J, Gotch F, Boshoff C (2003). Kaposi's sarcoma-associated herpesvirus cytotoxic T lymphocytes recognize and target Darwinian positively selected autologous K1 epitopes.. J Virol, 77(7), 4306 - 4314.
    • Ziegler J, Newton R, Bourboulia D, Casabonne D, Beral V, Mbidde E, Carpenter L, Reeves G, Parkin DM, Wabinga H, Mbulaiteye S, Jaffe H, Weiss R, Boshoff C, Uganda Kaposi's Sarcoma Study Group (2003). Risk factors for Kaposi's sarcoma: a case-control study of HIV-seronegative people in Uganda.. Int J Cancer, 103(2), 233 - 240. doi:10.1002/ijc.10818
    • Mason C, Markusen JF, Boshoff CH (2003). Methods employing cells derived from adult bone marrow.
    • Chakraborty R, Rees G, Bourboulia D, Cross AM, Dixon JR, D'Agostino A, Musoke R, Boshoff C, Rowland-Jones SL, Klenerman P (2003). Viral coinfections among African children infected with human immunodeficiency virus type 1. Clinical Infectious Diseases, 36(7), 922 - 924.
    • Field N, Low W, Daniels M, Howell S, Daviet L, Boshoff C, Collins M (2003). KSHV vFLIP binds to IKK-gamma to activate IKK. Journal of Cell Science, 116, 3721 - 3728.
    • Godfrey A, Laman H, Boshoff C (2003). RNA interference: a potential tool against Kaposi's sarcoma-associated herpesvirus. Current Opinion in Infectious Diseases, 16, 593 - 600.
    • Boshoff C (2003). Kohn to Kaposi. NAT MED, 9(3), 262 - 262. doi:10.1038/nm0303-262
    • Newton R, Ziegler J, Bourboulia D, Casabonne D, Beral V, Mbidde E, Carpenter L, Reeves G, Parkin DM, Wabinga H, Mbulaiteye S, Jaffe H, Weiss R, Boshoff C, Uganda Kaposi's Sarcoma Study Group (2003). The sero-epidemiology of Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) in adults with cancer in Uganda.. Int J Cancer, 103(2), 226 - 232. doi:10.1002/ijc.10817
    • Boshoff C (2003). Kaposi virus scores cancer coup. Nature Medicine, 9(3), 261 - 262.

    2002

    • Boshoff C (2002). Targets for treatment: Lessons from aids-related malignancies. BRIT J CANCER, 86, S11 - S11.
    • Gill J, Bourboulia D, Wilkinson J, Hayes P, Cope A, Marcelin AG, Calvez V, Gotch F, Boshoff C, Gazzard B (2002). Prospective study of the effects of antiretroviral therapy on Kaposi sarcoma-associated herpesvirus infection in patients with and without Kaposi sarcoma. JAIDS-J ACQ IMM DEF, 31(4), 384 - 390.
    • Boshoff C, Weiss R (2002). AIDS-related malignancies.. Nat Rev Cancer, 2(5), 373 - 382. doi:10.1038/nrc797
    • Oksenhendler E, Boulanger E, Galicier L, Du MQ, Dupin N, Diss TC, Hamoudi R, Daniel MT, Agbalika F, Boshoff C, Clauvel JP, Isaacson PG, Meignin V (2002). High incidence of Kaposi sarcoma-associated herpesvirus-related non-Hodgkin lymphoma in patients with HIV infection and multicentric Castleman disease.. Blood, 99(7), 2331 - 2336.
    • Wilkinson J, Cope A, Gill J, Bourboulia D, Hayes P, Imami N, Kubo T, Marcelin A, Calvez V, Weiss R, Gazzard B, Boshoff C, Gotch F (2002). Identification of Kaposi's sarcoma-associated herpesvirus (KSHV)-specific cytotoxic T-lymphocyte epitopes and evaluation of reconstitution of KSHV-specific responses in human immunodeficiency virus type 1-infected patients receiving highly active antiretroviral therapy. J VIROL, 76(6), 2634 - 2640. doi:10.1128/JVI.76.6.2634-2640.2002
    • Gill J, Bourboulia D, Wilkinson J, Hayes P, Cope A, Marcelin AG, Calvez V, Gotch F, Boshoff C, Gazzard B (2002). Prospective study of the effects of antiretroviral therapy on Kaposi sarcoma-associated herpesvirus infection in patients with and without Kaposi sarcoma. JAIDS: Journal of Acquired Immune Deficiency Syndromes, 31(4), 384 - 390.
    • Boshoff C (2002). Kaposi's sarcoma biology. IUBMB Life, 53(4-5), 259 - 261.
    • Newton R, Ziegler J, Ateenyi-Agaba C, Bousarghin L, Casabonne D, Beral V, Mbidde E, Carpenter L, Reeves G, Parkin DM, Wabinga H, Mbulaiteye S, Jaffe H, Bourboulia D, Boshoff C, Touze A, Coursaget P (2002). The epidemiology of conjunctival squamous cell carcinoma in Uganda. British Journal of Cancer, 87(3), 301 - 308.
    • Wang HW, Sharp TV, Koumi A, Koentges G, Boshoff C (2002). Characterization of an anti-apoptotic glycoprotein encoded by Kaposi's sarcoma-associated herpesvirus which resembles a spliced variant of human survivin. The EMBO Journal, 21(11), 2602 - 2615. doi:10.1093/emboj/21.11.2602
    • Zong J, Ciufo DM, Viscidi R, Alagiozoglou L, Tyring S, Rady P, Orenstein J, Boto W, Kalumbuja H, Romano N, Melbye M, Kang GH, Boshoff C, Hayward GS (2002). Genotypic analysis at multiple loci across Kaposi's sarcoma herpesvirus (KSHV) DNA molecules: clustering patterns, novel variants and chimerism.. J Clin Virol, 23(3), 119 - 148.
    • Sharp TV, Wang HW, Koumi A, Hollyman D, Endo Y, Ye H, Du MQ, Boshoff C (2002). K15 protein of Kaposi's sarcoma-associated herpesvirus is latently expressed and binds to HAX-1, a protein with antiapoptotic function.. J Virol, 76(2), 802 - 816.
    • Hamoudi RA, Diss TC, Oksenhendler E, Pan LX, Carbone A, Boshoff C, Isaacson P, Du MQ (2002). Different cellular origin between primary effusion lymphoma with and without EBV infection..
    • Boshoff C (2002). Kaposi's sarcoma biology. IUBMB LIFE, 53(4-5), 259 - 261. doi:10.1080/15216540290099034
    • Jenner RG, Boshoff C (2002). The molecular pathology of Kaposi's sarcoma-associated herpesvirus. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1602(1), 1 - 22.

    2001

    • Boshoff C, Weiss R (2001). Cancer processes in immunodeficient populations: an introduction.. Eur J Cancer, 37(10), 1202 - 1208.
    • Gambús G, Bourboulia D, Esteve A, Lahoz R, Rodriguez C, Bolao F, Sirera G, Muga R, del Romero J, Boshoff C, Whitby D, Casabona J (2001). Prevalence and distribution of HHV-8 in different subpopulations, with and without HIV infection, in Spain.. AIDS, 15(9), 1167 - 1174.
    • Low W, Harries M, Ye H, Du MQ, Boshoff C, Collins M (2001). Internal ribosome entry site regulates translation of Kaposi's sarcoma-associated herpesvirus FLICE inhibitory protein.. J Virol, 75(6), 2938 - 2945. doi:10.1128/JVI.75.6.2938-2945.2001
    • Boshoff C, Weiss RA (2001). Epidemiology and pathogenesis of Kaposi's sarcoma-associated herpesvirus. Philosophical Transactions of the Royal Society B: Biological Sciences, 356(1408), 517 - 534.
    • Davidovici B, Karakis I, Bourboulia D, Ariad S, Zong JC, Benharroch D, Dupin N, Weiss R, Hayward G, Sarov B, Boshoff C (2001). Seroepidemiology and molecular epidemiology of Kaposi's sarcoma-associated herpesvirus among Jewish population groups in Israel. Journal of the National Cancer Institute, 93(3), 194 - 202. doi:10.1093/jnci/93.3.194
    • Boshoff C (2001). Gammaherpesviral infections and neoplasia in immunocompromised populations.
    • Du MO, Liu H, Diss TC, Hamoudi RA, Ye H, Dupin N, Oksenhendler E, Boshoff C, Isaacson PG (2001). KSHV infects monotypic (IgM lambda) but polyclonal naive B-cells in Castleman's disease and associated lymphoproliferative disorders. J PATHOL, 193, 3A - 3A.
    • Jenner RG, Alba MM, Boshoff C, Kellam P (2001). Kaposi's sarcoma-associated herpesvirus latent and lytic gene expression as revealed by DNA arrays. Journal of Virology, 75(2), 891 - 902.
    • Laman H, Boshoff C (2001). Is KSHV lytic growth induced by a methylation-sensitive switch?. Trends in Microbiology, 9(10), 464 - 466.
    • Boshoff C, Chang Y (2001). Kaposi's sarcoma-associated herpesvirus: a new DNA tumor virus.. Annu Rev Med, 52, 453 - 470. doi:10.1146/annurev.med.52.1.453
    • Du MQ, Liu H, Diss TC, Ye H, Hamoudi RA, Dupin N, Meignin V, Oksenhendler E, Boshoff C, Isaacson PG (2001). Kaposi sarcoma-associated herpesvirus infects monotypic (IgM lambda) but polyclonal naive B cells in Castleman disease and associated lymphoproliferative disorders.. Blood, 97(7), 2130 - 2136.

    2000

    • Codish S, Abu-Shakra M, Ariad S, Zirkin HJ, Yermiyahu T, Dupin N, Boshoff C, Sukenik S (2000). Manifestations of three HHV-8-related diseases in an HIV-negative patient: immunoblastic variant multicentric Castleman's disease, primary effusion lymphoma, and Kaposi's sarcoma.. Am J Hematol, 65(4), 310 - 314.
    • Radkov SA, Kellam P, Boshoff C (2000). The latent nuclear antigen of Kaposi sarcoma-associated herpesvirus targets the retinoblastoma-E2F pathway and with the oncogene Hras transforms primary rat cells.. Nat Med, 6(10), 1121 - 1127. doi:10.1038/80459
    • Boshoff C (2000). Kaposi's sarcoma herpesvirus: from cell biology to pathogenesis. AIDS, 14, S5 - S5.
    • Zago A, Bourboulia D, Viana MC, Collandre H, Dietze R, Boshoff C, Keller R (2000). Seroprevalence of human herpesvirus 8 and its association with Kaposi sarcoma in Brazil.. Sex Transm Dis, 27(8), 468 - 472.
    • Weiss R, Boshoff C (2000). Addressing controversies over Kaposi's sarcoma.. J Natl Cancer Inst, 92(9), 677 - 679.
    • Ariad S, Benharroch D, Lupu L, Davidovici B, Dupin N, Boshoff C (2000). Early peripheral lymph node involvement of human herpesvirus 8-associated, body cavity-based lymphoma in a human immunodeficiency virus-negative patient.. Arch Pathol Lab Med, 124(5), 753 - 755. doi:10.1043/0003-9985(2000)124<0753:EPLNIO>2.0.CO;2
    • Dupin N, Diss T, Kellam P, Tulliez M, Du MQ, Sicard D, Weiss RA, Isaacson PG, Boshoff C (2000). HHV-8 is associated with a plasmablastic variant of Castleman disease that is linked to HHV-8-positive plasmablastic lymphoma. BLOOD, 95(4), 1406 - 1412.
    • Eisen T, Boshoff C, Mak I, Sapunar F, Vaughan MM, Pyle L, Johnston SR, Ahern R, Smith IE, Gore ME (2000). Continuous low dose Thalidomide: a phase II study in advanced melanoma, renal cell, ovarian and breast cancer.. Br J Cancer, 82(4), 812 - 817. doi:10.1054/bjoc.1999.1004
    • Whitby D, Luppi M, Sabin C, Barozzi P, Di Biase AR, Balli F, Cucci F, Weiss RA, Boshoff C, Torelli G (2000). Detection of antibodies to human herpesvirus 8 in Italian children: evidence for horizontal transmission. British Journal of Cancer, 82(3), 702 - 704.
    • Mittnacht S, Boshoff C (2000). Viral cyclins.. Rev Med Virol, 10(3), 175 - 184.
    • Oksenhendler E, Meignin V, Dupin N, Boshoff C, Isaacson PG, Clauvel JP (2000). High incidence of non-Hogkin's lymphoma (NHL) in HIV/HHV8 associated Castleman's disease (CD). J ACQ IMMUN DEF SYND, 23(3), A24 - A24.
    • Sharp TV, Boshoff C (2000). Kaposi's sarcoma-associated herpesvirus: from cell biology to pathogenesis.. IUBMB Life, 49(2), 97 - 104. doi:10.1080/15216540050022395
    • Stine JT, Wood C, Hill M, Epp A, Raport CJ, Schweickart VL, Endo Y, Sasaki T, Simmons G, Boshoff C, Clapham P, Chang Y, Moore P, Gray PW, Chantry D (2000). KSHV-encoded CC chemokine vMIP-III is a CCR4 agonist, stimulates angiogenesis, and selectively chemoattracts TH2 cells.. Blood, 95(4), 1151 - 1157.

    1999

    • Whitby D, Smith NA, Matthews S, O'Shea S, Sabin CA, Kulasegaram R, Boshoff C, Weiss RA, de Ruiter A, Best JM (1999). Human herpesvirus 8: seroepidemiology among women and detection in the genital tract of seropositive women.. J Infect Dis, 179(1), 234 - 236. doi:10.1086/314563
    • Boshoff C (1999). Kaposi's sarcoma associated herpesvirus. CANCER SURV, 33, 157 - 190.
    • Ablashi D, Chatlynne L, Cooper H, Thomas D, Yadav M, Norhanom AW, Chandana AK, Churdboonchart V, Kulpradist SA, Patnaik M, Liegmann K, Masood R, Reitz M, Cleghorn F, Manns A, Levine PH, Rabkin C, Biggar R, Jensen F, Gill P, Jack N, Edwards J, Whitman J, Boshoff C (1999). Seroprevalence of human herpesvirus-8 (HHV-8) in countries of Southeast Asia compared to the USA, the Caribbean and Africa.. Br J Cancer, 81(5), 893 - 897. doi:10.1038/sj.bjc.6690782
    • Bourboulia D, Boshoff C, Sitas F (1999). HHV-8 peripheral-blood viral load and the titer of antibodies against HHV-8 - Reply. NEW ENGL J MED, 341(16), 1242 - 1242.
    • DeMartini JC, Halsey W, Boshoff C, York D, Howell MD (1999). Comparison of a maedi-visna virus CA-TM fusion protein ELISA with other assays for detecting sheep infected with North American ovine lentivirus strains.. Vet Immunol Immunopathol, 71(1), 29 - 40.
    • Osman M, Kubo T, Gill J, Neipel F, Becker M, Smith G, Weiss R, Gazzard B, Boshoff C, Gotch F (1999). Identification of human herpesvirus 8-specific cytotoxic T-cell responses.. J Virol, 73(7), 6136 - 6140.
    • Sitas F, Carrara H, Beral V, Newton R, Reeves G, Bull D, Jentsch U, Pacella-Norman R, Bourboulia D, Whitby D, Boshoff C, Weiss R (1999). Antibodies against human herpesvirus 8 in black South African patients with cancer.. N Engl J Med, 340(24), 1863 - 1871. doi:10.1056/NEJM199906173402403
    • Sitas F, Newton R, Boshoff C (1999). Increasing probability of mother-to-child transmission of HHV-8 with increasing maternal antibody titer for HHV-8.. N Engl J Med, 340(24), 1923 - . doi:10.1056/NEJM199906173402414
    • Kellam P, Bourboulia D, Dupin N, Shotton C, Fisher C, Talbot S, Boshoff C, Weiss RA (1999). Characterization of monoclonal antibodies raised against the latent nuclear antigen of human herpesvirus 8.. J Virol, 73(6), 5149 - 5155.
    • Boshoff C, Weiss RA (1999). Introduction. Semin Cancer Biol, 9(3), 149 - 150. doi:10.1006/scbi.1999.0120
    • Boshoff C, Weiss RA (1999). HHV8/KSHV - Introduction. SEMIN CANCER BIOL, 9(3), 149 - 150.
    • Boshoff C (1999). Human herpesvirus-8 encoded chemokines.
    • Pellett PE, Spira TJ, Bagasra O, Boshoff C, Corey L, de Lellis L, Huang ML, Lin JC, Matthews S, Monini P, Rimessi P, Sosa C, Wood C, Stewart JA (1999). Multicenter comparison of PCR assays for detection of human herpesvirus 8 DNA in semen.. J Clin Microbiol, 37(5), 1298 - 1301.
    • Talbot SJ, Weiss RA, Kellam P, Boshoff C (1999). Transcriptional analysis of human herpesvirus-8 open reading frames 71, 72, 73, K14, and 74 in a primary effusion lymphoma cell line.. Virology, 257(1), 84 - 94.
    • Dupin N, Fisher C, Kellam P, Ariad S, Tulliez M, Franck N, van Marck E, Salmon D, Gorin I, Escande JP, Weiss RA, Alitalo K, Boshoff C (1999). Distribution of human herpesvirus-8 latently infected cells in Kaposi's sarcoma, multicentric Castleman's disease, and primary effusion lymphoma.. Proc Natl Acad Sci U S A, 96(8), 4546 - 4551.
    • Ellis M, Chew YP, Fallis L, Freddersdorf S, Boshoff C, Weiss RA, Lu X, Mittnacht S (1999). Degradation of p27(Kip) cdk inhibitor triggered by Kaposi's sarcoma virus cyclin-cdk6 complex.. EMBO J, 18(3), 644 - 653. doi:10.1093/emboj/18.3.644
    • Smith NA, Sabin CA, Gopal R, Bourboulia D, Labbet W, Boshoff C, Barlow D, Band B, Peters BS, de Ruiter A, Brown DW, Weiss RA, Best JM, Whitby D (1999). Serologic evidence of human herpesvirus 8 transmission by homosexual but not heterosexual sex. The Journal of Infectious Diseases, 180(3), 600 - 606.

    1998

    • Luppi M, Barozzi P, Morabito F, Iannitto E, Tabilio A, Cavanna L, Vallisa D, Giacca M, Cucci F, Ferrari MG, Morselli M, Marasca R, Whitby D, Boshoff C, Weiss RA, Torelli G (1998). HHV-8 infection in blood donors and patients with malignant and reactive lymphoproliferations from different regions of Italy.
    • Whitby D, Luppi M, Barozzi P, Boshoff C, Weiss RA, Torelli G (1998). Human herpesvirus 8 seroprevalence in blood donors and lymphoma patients from different regions of Italy.. J Natl Cancer Inst, 90(5), 395 - 397.
    • Boshoff C, Gao SJ, Healy LE, Matthews S, Thomas AJ, Coignet L, Warnke RA, Strauchen JA, Matutes E, Kamel OW, Moore PS, Weiss RA, Chang Y (1998). Establishing a KSHV+ cell line (BCP-1) from peripheral blood and characterizing its growth in Nod/SCID mice.. Blood, 91(5), 1671 - 1679.
    • Weiss RA, Whitby D, Talbot S, Kellam P, Boshoff C (1998). Human herpesvirus Type 8 and Kaposi's sarcoma. Journal of the National Cancer Institute Monographs, 23, 51 - 54.
    • Conraads VM, Colebunders RL, Boshoff C, Van Marck E, Bosmans JM, Claeys MJ, Vrints CJ (1998). Primary pulmonary hypertension in a patient with HIV infection.. Acta Cardiol, 53(6), 367 - 369.
    • Bourboulia D, Whitby D, Boshoff C, Newton R, Beral V, Carrara H, Lane A, Sitas F (1998). Serologic evidence for mother-to-child transmission of Kaposi sarcoma-associated herpesvirus infection.. JAMA, 280(1), 31 - 32.
    • Boshoff C (1998). Viral pirates on a cellular sea. NATURE, 391(6662), 24 - 24.
    • Boshoff C (1998). Kaposi's sarcoma. Coupling herpesvirus to angiogenesis.. Nature, 391(6662), 24 - 25. doi:10.1038/34054
    • Baldeweg T, Catalan J, Gazzard BG, Weiss RA, Boshoff C (1998). Kaposi's sarcoma and protection from HIV dementia. Science, 280, 362 - 362.
    • Whitby D, Boshoff C (1998). Kaposi's sarcoma herpesvirus as a new paradigm for virus-induced oncogenesis.. Curr Opin Oncol, 10(5), 405 - 412.
    • Luppi M, Whitby D, Barozzi P, Boshoff C, Weiss R, Cucci F, Torelli G (1998). Age- and sex-specific seroprevalence of human herpesvirus 8 in Jamaica - Response. J NATL CANCER I, 90(14), 1103 - 1104.
    • Boshoff C, Weiss RA (1998). Kaposi's sarcoma-associated herpesvirus.. Adv Cancer Res, 75, 57 - 86.

    1997

    • OLeary JJ, Kennedy M, Boshoff C, Issacson P, Gatter K (1997). Human herpes virus 8 (HHV8) localisation in Castleman's disease raises important questions in relation to disease pathogenesis. J PATHOL, 182, A11 - A11.
    • Boshoff C, Whitby D, Talbot S, Weiss RA (1997). Etiology of AIDS-related Kaposi's sarcoma and lymphoma.. Oral Dis, 3 Suppl 1, S129 - S132.
    • Boshoff C, Talbot S, Whitby D, Reeves J, Weiss RA (1997). AIDS associated tumors and HHV8. J ACQ IMMUN DEF SYND, 14(4), S9 - S9.
    • Oliver RTD, Boshoff C (1997). Adjuvant trials in bladder cancer: Scientific background, review, and new directions.
    • Boshoff C, Moore PS (1997). Kaposi's sarcoma--associated herpesvirus: a newly recognized pathogen.. AIDS Clin Rev, , 323 - 347.
    • Howard MR, Whitby D, Bahadur G, Suggett F, Boshoff C, Tenant-Flowers M, Schulz TF, Kirk S, Matthews S, Weller IVD, Tedder RS, Weiss RA (1997). Detection of human herpesvirus 8 DNA in semen from HIV-infected individuals but not healthy semen donors. AIDS, 11, F15 - F19.
    • Boshoff C, Weiss RA (1997). Kaposi's sarcoma-associated herpesvirus. CURR OPIN INFECT DIS, 10(1), 26 - 31.
    • Godden-Kent D, Talbot SJ, Boshoff C, Chang Y, Moore P, Weiss RA, Mittnacht S (1997). The cyclin encoded by Kaposi's sarcoma-associated herpesvirus stimulates cdk6 to phosphorylate the retinoblastoma protein and histone H1.. J Virol, 71(6), 4193 - 4198.
    • Torelli G, Luppi M, Barozzi P, Ferrari MG, Marasca R, Morselli M, CeccheriniNelli L, Boshoff C, Weiss R, Whitby D (1997). HHV-8 seroprevalence and DNA sequences in patients with lymphoproliferative disease and normal population from Italy.. J ACQ IMMUN DEF SYND, 14(4), 106 - 106.
    • Chetty R, Dada MA, Boshoff CH, Comley MA, Biddolph SC, Schneider JW, Mason DY, Pulford KA, Gatter KC (1997). TAL-1 protein expression in vascular lesions.. J Pathol, 181(3), 311 - 315. doi:10.1002/(SICI)1096-9896(199703)181:3<311::AID-PATH775>3.0.CO;2-B
    • Sitas F, Taylor L, Madhoo J, Cooper K, Carrara H, Boshoff C, Weiss RA (1997). Occurrence of human herpes virus 8 in Kaposi's sarcoma and other tumours in South Africa.. S Afr Med J, 87(8), 1020 - 1022.
    • Boshoff C, Endo Y, Collins PD, Takeuchi Y, Reeves JD, Schweickart VL, Siani MA, Sasaki T, Williams TJ, Gray PW, Moore PS, Chang Y, Weiss RA (1997). Angiogenic and HIV-inhibitory functions of KSHV-encoded chemokines.. Science, 278(5336), 290 - 294.
    • Gao SJ, Boshoff C, Jayachandra S, Weiss RA, Chang Y, Moore PS (1997). KSHV ORF K9 (vIRF) is an oncogene which inhibits the interferon signaling pathway.. Oncogene, 15(16), 1979 - 1985. doi:10.1038/sj.onc.1201571
    • Boshoff C, Weiss RA (1997). Aetiology of Kaposi's sarcoma: current understanding and implications for therapy.. Mol Med Today, 3(11), 488 - 494. doi:10.1016/S1357-4310(97)01116-7
    • Kellam P, Boshoff C, Whitby D, Matthews S, Weiss RA, Talbot SJ (1997). Identification of a major latent nuclear antigen, LNA-1, in the human herpesvirus 8 genome.. J Hum Virol, 1(1), 19 - 29.
    • Whitby D, Boshoff C, Luppi M, Torelli G (1997). Kaposi's sarcoma-associated herpesvirus infection and multiple myeloma.. Science, 278(5345), 1971 - 1972.

    1996

    • Chang Y, Ziegler J, Wabinga H, Katangole-Mbidde E, Boshoff C, Schulz T, Whitby D, Maddalena D, Jaffe HW, Weiss RA, Moore PS (1996). Kaposi's sarcoma-associated herpesvirus and Kaposi's sarcoma in Africa. Uganda Kaposi's Sarcoma Study Group.. Arch Intern Med, 156(2), 202 - 204.
    • Chang Y, Ziegler J, Wabinga H, KatangoleMbidde E, Boshoff C, Schulz T, Whitby D, Maddalena D, Jaffe HW, Weiss RA, Moore PS, Mugerwa JW, Katabira E, Mwidu S, Beral V, Newton R, Parkin M, DeCock K (1996). Kaposi's sarcoma-associated herpesvirus and Kaposi's sarcoma in Africa. ARCH INTERN MED, 156(2), 202 - 204.
    • OLeary JJ, Kennedy M, Boshoff C, Weiss R, McGee JO, Cooper K, Jones RR, Williams I, Picton S, Howells D, Lucas S (1996). Kaposi's sarcoma associated Herpes virus human herpes virus 8: Have we really found the cause of Kaposi's sarcoma?. J PATHOL, 179, A10 - A10.
    • Boshoff C, Talbot S, Kennedy M, O'Leary J, Schulz T, Chang Y (1996). HHV8 and skin cancers in immunosuppressed patients.. Lancet, 347(8997), 338 - 339.
    • Moore PS, Boshoff C, Weiss RA, Chang Y (1996). Molecular mimicry of human cytokine and cytokine response pathway genes by KSHV.. Science, 274(5293), 1739 - 1744.
    • Dada MA, Boshoff CH, Comley MA, Turley H, Schneider JW, Chetty R, Gatter KC (1996). Thymidine phosphorylase expression in Kaposi sarcoma.. J Clin Pathol, 49(5), 400 - 402.
    • Schulz TF, Boshoff CH, Weiss RA (1996). HIV infection and neoplasia.. Lancet, 348(9027), 587 - 591. doi:10.1016/S0140-6736(95)11033-X
    • Simpson GR, Schulz TF, Whitby D, Cook PM, Boshoff C, Rainbow L, Howard MR, Gao SJ, Bohenzky RA, Simmonds P, Lee C, deRuiter A, Hatzakis A, Tedder RS, Weller IVD, Weiss RA, Moore PS (1996). Prevalence of Kaposi's sarcoma associated herpesvirus infection measured by antibodies to recombinant capsid protein and latent immunofluorescence antigen. LANCET, 348(9035), 1133 - 1138.
    • Schultz TF, Boshoff C, Weiss RA (1996). HIV infection and neoplasia - Reply. LANCET, 348(9037), 1318 - 1318.
    • Chang Y, Moore PS, Talbot SJ, Boshoff CH, Zarkowska T, Godden-Kent , Paterson H, Weiss RA, Mittnacht S (1996). Cyclin encoded by KS herpesvirus.. Nature, 382(6590), 410 - . doi:10.1038/382410a0
    • Boshoff C, Talbot S, Kennedy M, O'Leary J, Schulz T, Chang Y (1996). HHV8 and skin cancers in immunosuppressed patients.. Lancet, 348(9020), 138 - .

    1995

    • Boshoff C, Schulz TF, Kennedy MM, Graham AK, Fisher C, Thomas A, McGee JO, Weiss RA, O'Leary JJ (1995). Kaposi's sarcoma-associated herpesvirus infects endothelial and spindle cells.. Nat Med, 1(12), 1274 - 1278.
    • Boshoff C, Oliver RT, Gallagher CJ, Ong J (1995). Accelerated cisplatin-based chemotherapy for advanced bladder cancer.. Eur J Cancer, 31A(10), 1633 - 1636.
    • Boshoff C, Whitby D, Hatziioannou T, Fisher C, van der Walt J, Hatzakis A, Weiss R, Schulz T (1995). Kaposi's-sarcoma-associated herpesvirus in HIV-negative Kaposi's sarcoma.. Lancet, 345(8956), 1043 - 1044.
    • SANDS R, BOSHOFF C, JONES A, STUDD J (1995). CURRENT OPINION - HORMONE REPLACEMENT THERAPY AFTER A DIAGNOSIS OF BREAST-CANCER. MENOPAUSE, 2(2), 73 - 80.
    • WHITBY D, HOWARD MR, TENANTFLOWERS M, BRINK NS, COPAS A, BOSHOFF C, HATZIOANNOU T, SUGGETT FEA, ALDAM DM, DENTON AS, MILLER RF, WELLER IVD, WEISS RA, TEDDER RS, SCHULZ TF (1995). DETECTION OF KAPOSI-SARCOMA ASSOCIATED HERPESVIRUS IN PERIPHERAL-BLOOD OF HIV-INFECTED INDIVIDUALS AND PROGRESSION TO KAPOSIS-SARCOMA. LANCET, 346(8978), 799 - 802.
    • Boshoff C, Begent RH, Oliver RT, Rustin GJ, Newlands ES, Andrews R, Skelton M, Holden L, Ong J (1995). Secondary tumours following etoposide containing therapy for germ cell cancer.. Ann Oncol, 6(1), 35 - 40.

    1994

    • Boshoff C, Rustin G, Begent R, Oliver T, Newlands E, Holden L, Ong J (1994). Treatment of good-risk, stage II, non-seminomatous testis cancer.. Lancet, 344(8929), 1085 - 1086.
    • Boshoff C, Edmonds PM, Gallagher CJ (1994). Cuffed polyurethane catheter for ambulatory infusional chemotherapy.. Br J Hosp Med, 52(4), 171 - 174.