If you are at UCL and interested in working with the CfMR, please email Michael Duchen
Prof Alison Lloyd
Personal Profile
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Profile
Research Description
Research Activities
Cell Growth and Regeneration
Leukocyte trafficking in tissue damage
Education Description
UCL Collaborators
Prof Ashley Groves; Dr Joanna Porter; Prof David Moores
External Collaborators
Publications
- Roberts SA, Lloyd AC (2012). Aspects of cell growth control illustrated by the Schwann cell.. Curr Opin Cell Biol, 24(6), 852 - 857. doi:10.1016/j.ceb.2012.10.003
- Kalamarides M, Acosta MT, Babovic-Vuksanovic D, Carpen O, Cichowski K, Evans DG, Giancotti F, Hanemann CO, Ingram D, Lloyd AC, Mayes DA, Messiaen L, Morrison H, North K, Packer R, Pan D, Stemmer-Rachamimov A, Upadhyaya M, Viskochil D, Wallace MR, Hunter-Schaedle K, Ratner N (2012). Neurofibromatosis 2011: a report of the Children's Tumor Foundation annual meeting. Acta Neuropathol, 123(3), 369 - 380. doi:10.1007/s00401-011-0905-0
- Collins MJ, Napoli I , Ribeiro S, Roberts S, Lloyd AC (2012). Loss of Rb Cooperates with Ras to Drive Oncogenic Growth in Mammalian Cells.. Current Biology, 22(19), 1765 - 1773.
- Napoli I, Noon LA, Ribeiro S, Kerai AP, Parrinello S, Rosenberg LH, Collins MJ, Harrisingh MC, White IJ, Woodhoo A, Lloyd AC (2012). A central role for the ERK-signaling pathway in controlling Schwann cell plasticity and peripheral nerve regeneration in vivo.. Neuron, 73(4), 729 - 742. doi:10.1016/j.neuron.2011.11.031
- Feber A, Wilson GA, Zhang L, Presneau N, Idowu B, Down TA, Rakyan VK, Noon LA, Lloyd AC, Stupka E, Schiza V, Teschendorff AE, Schroth GP, Flanagan A, Beck S (2011). Comparative methylome analysis of benign and malignant peripheral nerve sheath tumors.. Genome Res, 21(4), 515 - 524. doi:10.1101/gr.109678.110
- Parrinello S, Napoli I, Ribeiro S, Wingfield Digby P, Fedrova M, Parkinson DB, Doddrell RDS, Nakayama M, Adams RH, Lloyd AC (2010). EphB signalling directs peripheral nerve regeneration through Sox2-dependent Schwann cell sorting. Cell, 143, 145 - 155.
- Danovi D, Cremona CA, Machado-da-Silva G, Basu S, Noon LA, Parrinello P, Lloyd AC (2010). A genetic screen for anchorage-independent proliferation in mammalian cells identifies a membrane-bound neuregulin. PLoSONE, 5(7), e11774 - .
- Parrinello , Lloyd SA, A C (2009). Neurofibroma development in NF1--insights into tumour initiation.. Trends in Cell Biology, 19(8), 395 - 403.
- Echave P, Machado-da-Silva G, Arkell RS, Duchen MR, Jacobson J, Mitter R, Lloyd AC (2009). Extracellular growth factors and mitogens cooperate to drive mitochondrial biogenesis.. Journal of Cell Science, 122(24), 4516 - 4525.
- Cremona CA, Lloyd AC (2009). Loss of anchorage in checkpoint-deficient cells increases genomic instability and promotes oncogenic transformation.. J Cell Sci, 122(Pt 18), 3272 - 3281. doi:10.1242/jcs.047126
- Rubio D, Garcia S, Paz MF, De LCT, Lopez-Fernandez LA, Lloyd AC, Garcia-Castro J, Bernad A (2008). Molecular characterization of spontaneous mesenchymal stem cell transformation.. PLoS ONE, 3(1), e1398 - .
- Parkinson DB, Bhaskaran A, Arthur-Farraj P, Noon LA, Woodhoo A, Lloyd AC, Feltri ML, Wrabetz L, Behrens A, Mirsky R, Jessen KR (2008). c-Jun is a negative regulator of myelination. The Journal of Cell Biology, 181(4), 625 - 637. doi:10.1083/jcb.200803013
- Parrinello S, Noon LA, Harrisingh MC, Wingfield Digby P, Echave P, Cremona CA, Rosenberg LH, Flanagan AM, Parada LF, Lloyd AC (2008). NF1 loss disrupts Schwann cell-axonal interactions: a novel role for semaphorin 4F.. Genes and Development, 22(23), 3335 - 3348.
- Echave P, Conlon IJ, Lloyd AC (2007). Cell size regulation in mammalian cells.. Cell Cycle, 6(2), 218 - 224.
- Noon LA, Lloyd AC (2007). Treating Leprosy: an Erb-al remedy?. Trends in Pharmacological Sciences, 28(3), 103 - 105.
- Rubio D, Garcia S, De LCT, Paz MF, Lloyd AC, Bernad A, Garcia-Castro J (2007). Human mesenchymal stem cell transformation is associated with a mesenchymal-epithelial transition.. Experimental Cell Research, 314(4), 691 - 698.
- Lloyd AC (2006). Distinct functions for ERKs?. Journal of Biology, 5, 13 - .
- Noon LAAL, A C (2005). Hijacking the ERK signaling pathway: Mycobacterium leprae shuns MEK to drive the proliferation of infected Schwann cells.. Science STKE, 309, pe52 - .
- Rubio D, Garcia-Castro J, Martin MC, de LFR, Cigudosa JC, Lloyd ACABA (2005). Spontaneous human adult stem cell transformation. cancer research, 65(8), 3035 - 3039.
- Harrisingh MC, Lloyd AC (2004). Ras/Raf/ERK signalling and NF1.. Cell Cycle, 3(10), 1255 - 1258.
- Harrisingh MC, Perez-Nadales E, Parkinson DB, Malcolm DS, Mudge AW, Lloyd AC (2004). The Ras/Raf/ERK signalling pathway drives Schwann cell dedifferentiation.. The EMBO Journal, 23(15), 3061 - 3071. doi:10.1038/sj.emboj.7600309
- Conlon I, Lloyd AC, Raff MC (2004). Co-ordination of cell growth and cell-cycle progression in proliferating mammalian cells.. In Hall MN, Raff M, Thomas G (Ed.), Cell Growth: Control of Cell Size (pp. 85 - 101). : Cold Spring Harbour Laboratory Press.
- Perez-Nadales E, Lloyd AC (2004). Essential function for ErbB3 in breast cancer proliferation.. Breast Cancer Research, 6, 137 - 139.
- Mitchell PJ, Perez-Nadales E, Malcolm DS, Lloyd AC (2003). Dissecting the Contribution of p16 INK4A and the Rb Family to the Ras Transformed Phenotype. Molecular and Cellular Biology, 23(7), 2530 - 2542. doi:10.1128/MCB.23.7.2530-2542.2003
- Lloyd AC (2002). Limits to lifespan.. Nat Cell Biol, 4(2), E25 - E27. doi:10.1038/ncb0202-e25
- Lloyd AC (2002). Limits to Lifespan. Nature Cell Biology, 4, 0 - 0.
- Mathon NF, Lloyd AC (2001). Cell Senescence and Cancer. Nature Reviews Cancer, 1, 203 - 213.
- Tang DG, Tokumoto YM, Apperly JA, Lloyd AC, Raff MC (2001). Lack of replicative senescence in cultured oligodendrocyte precursor cells. Science, 291(5505), 868 - 871. doi:10.1126/science.1056780
- Mathon NF, Malcolm DS, Harrisingh MC, Cheng L, Lloyd AC (2001). Lack of replicative senescence in normal rodent glia. Science, 291, 872 - 875. doi:10.1126/science.1056782
- (2000). p53: Only ARF the story. Nature Cell Biology, 2, 48 - 50.
- Lloyd AC (1998). Ras versus cyclin-dependent kinase inhibitors. Current Opinion in Genetics and Development, 8, 43 - 48.
- Lloyd AC, Obermuller F, Staddon S, Barth C, McMahon M, Land H (1997). Co-operating Oncogenes Target Cyclin/Cdk Activity. Genes and Development, 11, 663 - 677.
- Sewing A, Wiseman B, Lloyd AC, Land H (1997). high Intensity Raf Signal Causes Cell-Cycle Arrest Mediated by p21Cip1.. Molecular and Cellular Biology, 17, 5588 - 5597.
- Lloyd AC, Yancheva N, Wasylyk B (1991). Transformation suppressor Activity of a Jun transcription Factor Lacking its Activation Domain. Nature, 352, 635 - 638.
- Marshall CJ, Lloyd AC, Morris JD, Paterson H, Price B, Hall A (1989). Signal transduction by p21ras.. International Journal of Cancer - Supplement, 4, 29 - 31.
- Lloyd AC, Davies SA, Crossley I, Whitaker M, Houslay MD, Hall A, Marshall CJ, Wakelam MJO (1989). Bombesin stimulation of inositol 1,4,5-trisphosphate generation and intracellular calcium release is amplified in a cell line overexpressing the N-ras proto-oncogene.. Biochemical Journal, 260, 813 - 819.
- Morris JDH, Price B, Lloyd AC, Self AJ, Marshall CJ, Hall A (1989). Scrape-loading of Swiss 3T3 cells with ras protein rapidly activates protein kinase C in the absence of phosphoinositide hydrolysis.. Oncogene, 4, 27 - 31.
- Lloyd AC, Paterson HF, Morris JD, Hall A, Marshall CJ (1989). p21H-Ras Induced Morphological Transformation and Increases in c-myc Expression are Independent of functional Protein kinase C. The EMBO Journal, 8, 1099 - 1104.
- Flores P, Gutman A, Imler JL, Lloyd AC, Schneikert J, Wasylyk C, Wasylyk B (1989). AP1 and PEA3 are Nuclear targets for Transcriptional Activation by Non-nuclear oncogenes. Hormones and Cell Regulation, 198, 57 - 62.
- Hall A, Cales C, Hancock JF, Lloyd AC, Self A, Gardener S, Houslay MD, Wakelam MJ, Marshall CJ (1988). Analysis of mammalian Ras effector function. Cold Spring Harbor Symposium on Quantitative Biology, 53, 855 - 862.
- Lloyd AC, Carpenter CA, Saggerson ED (1986). Intertissue differences in the hysteretic behaviour of carnitine palmitoyltransferase in the presence of malonyl-CoA. Biochemical Journal, 237, 289 - 291.
- NAPOLI I, NOON L, RIBEIRO S, KERAI A, PARRINELLO S, ROSENBERG L, COLLINS M, HARRISINGH M, WHITE I, WOODHOO A, LLOYD A (). A central role for the ERK-signaling pathway in controlling Schwann cell plasticity and peripheral nerve regeneration in vivo. NEURON, , - .
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