UCL CfMR5

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If you are at UCL and interested in working with the CfMR, please email Michael Duchen


People

Andrey Abramov

Parkinson Disease Society Senior Research Fellow

Pathophysiological mechanisms of mitochondrial mutations associated with Parkinson’s Disease.

Department: Molecular Neuroscience, UCL Institute of Neurology

Andrey Abramov

Margaret Ashcroft

Regulation and targeting of the hypoxia inducible factor (HIF) pathway

Department: Metabolism and Experimental Therapeutics, UCL Division of Medicine

Prof Margaret Ashcroft

James Baker

Organic Synthesis; Chemical Biology; Organic Photochemistry; Ligand Discovery

Department: Chemistry

James Baker

Chris Boshoff

Viral oncology; cancer biology and metabolism

Department: Cancer Biology, UCL Cancer Institute

Chris Boshoff

Neil Bradman

Use of genetic variation in the study of demographic history; Pharmacogenetics

Department: Division of Biosciences

Neil Bradman

Stephen Caddick

Chemical Biology; Organic Synthesis; Catalysis Synthetic Methodology; Diversity Oriented Synthesis; Protein Ligand Interactions; Structure based design; Medicinal chemistry

Department: Chemistry

Steve Caddick

Michelangelo Campanella

Roles of the mitochondrial proteins IF1 and the mitochondrial benzodiazepine receptor in the regulation of cell fate and disease

Department: Royal Veterinary College

Michelangelo Campanella

John Carroll

Cell signalling; mammalian oocytes and embryos; imaging; reproduction; roles of mitochondria in fertility

Department: Cell and Developmental Biology

Prof John Carroll

Chris Cooper

Non-invasive cytochrome oxidase measurements and mitochondrial kinetic modelling 

Honorary Professor of UCL in the Department of Medical Physics and Bioengineering

Department: Biological Sciences, University of Essex

Chris Cooper

J. Mark Cooper

Neurodegenerative diseases, in particular the investigation of the molecular mechanisms of Parkinson's disease

Department: Clinical Neurocience, UCL Institute of Neurology

Mark Cooper

Martin Crompton

Mitochondria; Permeability transition; Calcium;  Oxidative stress, Cyclophilins; Cell death

Department: Structural & Molecular Biology

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Michael Duchen

Neurodegenerative diseases; mitochondrial genetic disease; comparative mitochondrial cell biology; fluorescence imaging of mitochondrial function; cell death pathways; mitochondria and calcium signaling

Department: Cell and Developmental Biology

Prof Michael Duchen

Clare Elwell

Development of novel optical systems for monitoring the healthy and injured brain

Department: Medical Physics and Bioengineering

Prof Clare Elwell

Elizabeth Fisher

The neurogenetics of neurodegenerative disease

Department: Neurodegenerative Diseases, UCL Institute of Neurology

Elizabeth Fisher

Lazaros Foukas

Mammalian PI 3-kinase signalling and ageing

Department: Institute of Healthy Ageing, UCL Genetics, Evolution and Environment

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Jonathan Gale

Repair and regeneration of hair epithelia; mitochondrial dysfunction in deafness

Department: Ear Institute

Jonathan Gale

Alex Gourine 

Autonomic neuroscience.

Department: Neuroscience, Physiology & Pharmacology

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Ivan Gout

Regulation of growth and energy metabolism via the mTOR/S6K pathway in normal and cancer cells

Department: Structural and Molecular Biology


Prof Ivan Gout

Linda Greensmith

Development and Neurodegeneration of Motor Neurons; Motor Neuron Diseases; Neuromuscular Diseases

Department: Sobell Research Department of Motor Neuroscience & Movement Disorders

Linda Greensmith

Andrew Hall

Department: Centre for Nephrology

Dr Andrew Hall

John Hancock

Mathematical modelling of complex biological processes

Department: MRC Harwell

John Hancock

Michael Hanna

Human neuromuscular diseases and diseases related to mtDNA mutations

Department: Institute of Neurology

Michael Hanna

John Hardy

Neurological disease. Genetic studies of neurological disease, population genetics.

Department: Molecular Neuroscience, UCL Institute of Neurology

John Hardy

Derek J Hausenloy

Clinical Lecturer and Hon Consultant Cardiologist

Mitochondria and cardioprotection

Department: The Hatter Cardiovascular Institute, UCL

Derek Hauslenloy

Simon Heales

Mitochondrial dysfunction and oxidative stress in neurodegenerative disease

Department: Institute of Neurology

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Katherine Holt

Scanning Electrochemical Microscopy; Boron-doped Diamond Ultramicroelectrodes; Diamond Nanoparticles; Redox properties of living cells and cell components; Electrochemistry of model biological systems and biomimetic molecules; Electrochemical aspects of future energy technologies

Department: Chemistry

Katherine Holt

Stefan Howorka

Protein biochemistry and protein engineering; Bioconjugate chemistry; Single-molecule detection; Nanobiotechnology; Surface chemistry

Department: Chemistry

Stefan Howorka

Josef Kittler

Cell biological mechanisms underlying neuronal excitability and synaptic plasticity. Mitochondrial trafficking in neurons

Department: Neuroscience, Physiology & Pharmacology

Josef Kittler

Nick Lane

Provost's Venture Research Fellow

Mitochondria and evolution

Department: Genetics, Evolution and Environment

Nick Lane

Mark Lythgoe

Biomedical Imaging

Department: Centre for Advanced Biomedical Imaging


Mark Lythgoe

Derek MacMillan

Organic Synthesis; Carbohydrate and glycopeptide chemistry; Peptide and protein synthesis; Engineering and directed evolution of protein

Department: Chemistry

Derek MacMillan

Patrick Maxwell

Oxygen sensing; von Hippel Lindau disease;  Renal cancer; Genetics of renal disease

Department:
Metabolism and Experimental Therapeutics, UCL Division of Medicine

Patrick Maxwell

Adam McKay

Department: Chemistry

Adam McKay

Vidya Mohamed-Ali

Biology of adipocytes and the role of adipose tissue as an endocrine organ. Regulation of metabolism and obesity

Department: Metabolism and Experimental Therapeutics

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Salvador Moncada

NO biology; septic shock syndrome; regulation of mitochondrial metabolism

Department: Wolfson Institute of Biomedical Research

Prof Salvador Moncada

Hugh Montgomery

Critical care medicine; hypoxic adaptation; human performance; renin-angiotensin systems

Department: Division of Medicine

Hugh Montgomery
Steve Moss

Department: Institute of Ophthalmology
Prof Stephen Moss

Tom Mrsic-Flogel

Experience-dependent cortical plasticity; Circuits underlying sensory processing and behaviour

Department: Neuroscience, Physiology & Pharmacology

Tom Mrsic-Flogel

Francesco Muntoni

Paediatric neurology, neuromuscular disease

Department: Neurosciences & Mental Health, UCL Institute of Child Health

Francesco Muntoni

Arokia Nathan

Nano-structured electronic materials; Micro-/nano- electro-mechanical systems; Electronics on non-conventional substrates; Nano-scale thin film transistors and circuits; Biomedical imaging and protein crystallography; Organic light emitting diode displays

Department: Centre for Materials Research

Arokia Nathan

Richard Orrell

Clinical Neurosciences and Consultant Neurologist

Department: Clinical Neurosciences, Institute of Neurology

Prof Orrell

Linda Partridge

Biology of Ageing

Department: Genetics, Evolution & Environment

Linda Partridge

Saul Purton

The biology and biotechnology of algae

Department: Structural & Molecular Biology

Saul Purton
Shamima Rahman

Mitochondrial DNA replication and mutations

Department: Institute of Child Health


Shamina Rahman

Peter R Rich

Biological electron transfer; Infrared spectroscopy

Department: Structural & Molecular Biology

Peter Rich

Bill Richardson

Properties and functions of neural stem cells and their progeny in the embryonic and postnatal CNS

Department: Wolfson Institute of Biomedical Research

Bill Richardson

Anthony Schapira

Neurodegenerative diseases, particularly Parkinson's disease, Huntington's disease and Friedreich's Ataxia. Interest is mainly focused on the molecular mechanisms involved in pathogenesis. Additional research: mitochondrial dysfunction

Department: Clinical Neurocience, UCL Institute of Neurology

Anthony Schapira

Kenneth Smith

Pathophysiology of inflammatory demyelinating disease; Electrophysiology; Imaging; Nitric oxide

Department: Neuroinflammation, UCL Institute of Neurology

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Paul Simons

Neural development; Ageing; Neurodegeneration; Myloidosis

Department: Inflammation, UCL Division of Medicine

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Mervyn Singer

Sepsis; Multiple organ failure; Infection; Haemodynamics; Haemodynamic monitoring

Department: Clinical Physiology, UCL Division of Medicine

Mervyn Singer

Gyorgy Szabadkai

Mitochondrial replication and cancer; mitochondria and calcium signalling; mitochondria and cell death

Department: Cell and Developmental Biology

szabadkai

Jan Willem Taanman

Experimental cell culture models of neurodegenerative disease, including Parkinson's disease and mitochondrial encephalomyopathies

Department: Clinical Neurocience, UCL Institute of Neurology

Jan-Willem Taanman

Andy Tinker 

Ion channels in particular K channels; G-proteins and GPCRs; Cell signalling; Cardiac arrhythmia

Department: Metabolism and Experimental Therapeutics, UCL Division of Medicine

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Robert Unwin 

Renal tubular physiology and the regulation of ion transport

Department: Internal Medicine, UCL Division of Medicine

Robert Unwin
Jonathan Wilden

Department: Chemistry
Dr Johnathan Wilden

Dominic Withers 

The central nervous system regulation of energy homeostasis

Department: Metabolism and Experimental Therapeutics, UCL Division of Medicine

Dominic Withers

Nicholas Wood

Genetic basis of neurodegenerative disease

Department: Wolfson Institute of Biomedical Research

Nicholas Wood

Takehiro Yasukawa 

Mechanisms of mitochondrial DNA maintenance

Department: Wolfson Institute of Biomedical Research

Takehiro Yasukawa

Derek Yellon

The pathophysiology of ischaemia-reperfusion injury in the basic and clinical arena

Department: Cardiovascular Medicine, UCL Division of Medicine

Derek Yellon

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