Nick Everdell

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I joined the Biomedical Optics Research Laboratory in 2001. For the past few years I have been working on near infrared imaging systems. They are being used for topographic imaging of the brain cortex amongst other things. Click here to look at our web page about optical topography. For an overview document about the systems and their applications click here (downloadable pdf). Click here to look at a journal article (also pdf). I also help to develop and maintain the MONSTIR system, which is used for tomographic imaging of the brain and breast. Another project I've worked on is a new type of retinal imaging camera. There's some more details about that here. I've also been working on a wireless, portable spectroscopy system, designed primarily to look at muscle tissue oxygenation.

I did my PhD at Middlesex University, finishing in 2001. It involved designing and building a haemodialysis system for treating premature babies with acute renal failure. Such a system is needed because these babies are too small to be treated using conventional paediatric dialysis systems. The work was done in cooperation with the paediatric nephrology department of the Royal Victoria Infirmary, Newcastle. Click here for a short tv appearance that the system made (the video will take a while to start so be patient, or download it first).

Before that I did an MSc in Biomedical Engineering at Surrey University (Guildford).
My 1st degree was in Engineering, specializing in fluid mechanics.  

Contact

Nick Everdell
Senior Research Associate
Department of Medical Physics and Bioengineering
Malet Place Engineering Building
University College London
London WC1E 6BT
UK

Phone: (44-20) 7679-0267
Fax: (44-20) 7679-0255

Refereed articles

Everdell N L , D Airantzis, C Kolvya, T Suzuki, C E Elwell (2013) "A portable wireless near-infrared spatially resolved spectroscopy system for use on brain and muscle" Medical Engineering and Physics (in press)

Correia T, Lloyd-Fox S, N L Everdell, A Blasi, C Elwell, J C Hebden, A Gibson (2012) "Three-dimensional optical topography of brain activity in infants watching videos of human movement" Physics in Medicine and Biology 57 1135-1146

Cooper RJ, Hebden, JC, O'Reilly H, Mitra S, Mitchell A, Everdell NL, Gibson AP, Austin T (2011) "Transient haemodynamic events in neurologically compromised infants: A simultaneous EEG and diffuse optical imaging study" Neuroimage 55(4) 1610-1616 Download PDF file

Lloyd-Fox S, A Blasi, N L Everdell, C E Elwell, M H Johnson (2011) "Selective cortical mapping of biological motion processing in young infants" Journal of Cognitive Neuroscience 23(9) 2521-2532 Download PDF file

Everdell N L, I B Styles, A Calcagni, J Gibson, J Hebden, E Claridge (2010) "Multispectral imaging of the ocular fundus using LED illumination" Review of Scientific Instruments 81, 093706 Download PDF file

Correia T, A Banga, N L Everdell, A P Gibson, J C Hebden (2009) "A quantitative assessment of the depth sensitivity of an optical topography system using a solid dynamic tissue-phantom" Physics in Medicine and Biology 54 6277-6286 Download PDF file

Cooper R J, D Bhatt, N L Everdell, J C Hebden (2009) "A tissue-like, optically turbid and electrically conducting phantom for simultaneous EEG and near-infrared imaging" Physics in Medicine and Biology 54 N403-N408 Download PDF file

Cooper R J, N L Everdell, L C Enfield, ,A P Gibson, A Worley, J C Hebden (2009) "Design and evaluation of a probe for simultaneous EEG and near-infrared imaging of cortical activation" Physics in Medicine and Biology 54, 2093-2102 Download PDF file

Lloyd-Fox S, A Blasi, A Volein, N Everdell, C E Elwell, M H Johnson (2009) "Social Perception in Infancy: a near infrared spectroscopy study" Child Development 80(4), 986-999 Download PDF file

Hebden, JC, Correia, T, Khakoo, I, Gibson, AP, and Everdell, N (2008) "A dynamic optical imaging phantom based on an array of semiconductor diodes" Physics in Medicine and Biology 53, N407-N413

Hebden, JC, Brunker, J, Correia, T, Price, BD, Gibson, AP, and Everdell, N (2008): An electrically-activated dynamic tissue-equivalent phantom for assessment of diffuse optical imaging systems, Physics in Medicine and Biology 53, 329-337. Download PDF file.

Blasi, A, Fox, S, Everdell, N, Volein, A, Tucker, L, Csibra, G, Gibson, AP, Hebden, JC, Johnson, MH, and Elwell, CE (2007): Investigation of depth dependent changes in cerebral haemodynamics during face perception in infants, Physics in Medicine and Biology 52, 6849-6864. Download PDF file.

Enfield, LC, Gibson, AP, Everdell, NL, Delpy, DT, Schweiger, M, Arridge, SR, Richardson, C, Keshtgar, M, Douek, M, and Hebden, JC (2007): Three-dimensional time-resolved optical mammography of the uncompressed breast, Applied Optics 46, 3628-3638. Download PDF file.

Everdell N L (2007) "A haemodialysis system for the treatment of acute renal failure and metabolic disorders in neonates"  Medical Engineering and Physics 29(4),516-524. Download PDF file

Gibson A P, T Austin, N L Everdell, M Schweiger, S R Arridge, J Meek, J S Wyatt, D T Delpy, J C Hebden (2006) "Three-dimensional whole-head optical tomography of passive motor evoked responses in the neonate" Neuroimage 30, 521-528.

Everdell, NL, Gibson, AP, Tullis, IDC, Vaithianathan, T, Hebden, JC, and Delpy, DT (2005): A frequency multiplexed near infrared topography system for imaging functional activation in the brain, Review of Scientific Instruments 76(9). Download PDF file

Austin T, Gibson AP, Everdell NL, et al. (2005): Three dimensional optical imaging of neonatal brain activation, Pediatric Research 58 (2): 357-357

Yates, TD, Hebden, JC, Gibson, AP, Enfield, L, Everdell, NL, Arridge, SR, and Delpy, DT (2005): time-resolved optical mammography using a liquid coupled interface, Journal of Biomedical Optics  10(5) 054011

Everdell N L, M G Coulthard, J Crosier, M J Kier (2005) "A machine for haemodialysing very small infants" Pediatric Nephrology 20(5) 636-643. Download PDF file

Yates T D, J C Hebden, A P Gibson, N Everdell, S R Arridge, and M Douek (2005) "Optical tomography of the breast using a multi-channel time-resolved imager" Phys. Med. Biol. 50, 2503-2517.

Hebden J C, T D Yates, A P Gibson, N Everdell, S R Arridge, D W Chicken, M Douek, M R S Kashtgar (2005) "Monitoring recovery following laser surgery of the breast using optical tomography: a case
study" Appl. Opt. 44(10), 1898-1904

Gibson, A P, J C Hebden, J Riley, N Everdell, M Schweiger, S R Arridge, D T Delpy (2005) "Linear and non-linear reconstruction for optical tomography of phantoms with non-scattering regions" Appl. Opt. 44(19), 3925-3936

Vaithianathan T, I D C Tullis, N Everdell, T Leung, A P Gibson, D T Delpy (2004): The Design of a  portable infrared mapping system for functional imaging on babies Rev. Sci. Instrum. 75 (10) p3276-3283 .

Hebden J C, A Gibson, T Austin, R Md Yusof, N Everdell, D T Delpy, S R Arridge, J H Meek, J S Wyatt (2004) "Imaging changes in blood volume and oxygenation in the newborn infant brain using three-dimensional optical tomography" Phys. Med. Biol. 49(7) p1117-1130

Gibson A P, R Md Yusof, H Dehghani, J Riley, N Everdell, R Richards, J C Hebden, M Schweiger, S R Arridge, D T Delpy (2003). "Optical tomography of a realistic neonatal head phantom" Applied Optics 42(16) p1-8

Hebden J C, F M Gonzalez, A P Gibson, E M C Hillman, R Md. Yusof, N Everdell, D T Delpy, G Zaccanti and F Martelli (2003). "Assessment of an in situ temporal calibration method for time-resolved optical tomography," Journal of Biomedical Optics 8(1) p87-92

Hebden J C, A P Gibson, R Md Yusof, N Everdell, E M C Hillman, D T Delpy, S R Arridge, T Austin, J Meek, J S Wyatt (2002). "Three-dimensional optical tomography of the premature infant brain" Phys. Med. Biol. 47: 4155-4166

Selected conference proceedings

Everdell N L, I B Styles, E Claridge, J Hebden, A Calcagni, J Gibson (2009) "Multispectral Imaging of the Ocular Fundus using LED Illumination" OSA European Conferences on Biomedical Optics, Munich 14-18 June 2009

Enfield L C, A P Gibson, N L Everdell, J C Hebden, S R Arridge, A Sharma, R Sainsbury, M Douek, M Keshtger (2008) "Sensitivity and specificity of 3D optical mammography" OSA Biomedical Optics Topical Meeting St Petersburg, Florida 16-20 March 2008

Sharma A, L Enfield, A P Gibson, N L Everdell, M Schweiger, S Arridge , D T Delpy, J C Hebden, M Keshtgar, R S Sainsbury, M Douek (2007) "Breast optical tomography: sensitivities and specificities for the detection of cancer" 30th Annual San Antonio Breast Cancer Symposium, December 13-16, 2007 San Antonio: Breast Cancer Research and Treatment Volume:106 Pages:S49-S49

Minagawa-Kawai Y, A Shestakova, E Kushnerenko, H van der Lely, J Meek, J C Hebden, N Everdell, E Dupoux (2007) “Newborn’s brain responses to temporally and spectrally different sound changes measured with NIRS” Proceedings of International symposium: Topical problems of Biophotonics, Moscow (3-34), 250-251

Fox S, L Tucker, A Volein, G Csibra, M Johnson, A Blasi, N Everdell, J Hebden, C Elwell (2006) "Shedding light on the infant brain: A novel non-invasive method for studying brain function in young infants" Breakthroughs in Neuroscience and Mental Health MRC Showcase, London, UK.

Richardson C E, L Enfield, A P Gibson, N L Everdell, J C Hebden, S R Arridge, M R Keshtgar, R Sainsbury, M Douek (2006) "Non-invasive optical imaging in patients with breast cancer" European Society of Surgical Oncologists (ESSO) Conference, December 2006

Richardson C E, L Enfield, A P Gibson, N L Everdell, J C Hebden, S R Arridge, D T Delpy, M Keshtgar, R Sainsbury, M Douek (2006) "Imaging Breast Cancer Non-invasively Using Three Dimensional Optical Tomography" British Association of Surgical Oncologists

Richardson C E, L Enfield, A P Gibson, N L Everdell, J C Hebden, S R Arridge, D T Delpy, M Keshtgar, R Sainsbury, M Douek (2006) "Non-invasive three dimensional optical mammography" 8th Milan Breast Cancer Conference

Enfield L C, A P Gibson, N L Everdell, D T Delpy, and J C Hebden, S R Arridge, M Douek, and M R S Keshtgar (2006) "Three-dimensional time-resolved optical mammography of the uncompressed breast" OSA Biomedical Optics Topical Meetings, Washington DC

Gibson A P, N L Everdell, J C Hebden, T Austin, F Wong, J H Meek, J S Wyatt, M Schweiger, S R Arridge (2006) "Anatomically constrained optical tomography of the neonatal brain" OSA Biomedical Optics Topical Meetings, Miami

Austin T, A P Gibson, N L Everdell, J C Hebden, M Schweiger, S R Arridge, J H Meek, J S Wyatt (2005) "Three dimensional optical imaging of neonatal brain activation" Pediatric Research 58 (2): 357-357

Becker, W, Bergmann, A, Gibson, A, Everdell, N, Jennions, D, Schweiger, M, Arridge, SR, and Hebden, JC (2005): Multi-dimensional time-correlated single photon counting applied to diffuse optical tomography, Proc. SPIE 5693, 34-42. 

Gibson A P, T Austin, N Everdell, J Meek, J S Wyatt, M Schweiger, S R Arridge, D T Delpy, J C Hebden (2005) "3D optical tomography of the neonatal brain" Proc. SPIE 5859

Everdell N, A Gibson, I D C Tullis, T Vaithanian, J Hebden, D Delpy (2004). "A frequency multiplexed near infra-red topography system for imaging functional activation in the brain." OSA Biomedical Topic Meetings, Miami.

Hebden J C, Gibson, A P, Everdell N, Yusof R Md, Delpy D T (2004). "Three-dimensional optical imaging of hemodynamic and oxygenation changes in the newborn infant brain" OSA Biomedical Topic Meetings, Miami

Yates T D, J C Hebden, A P Gibson, S R Arridge, N L Everdell, M Douek, W Chicken, D T Delpy (2004). "Clinical results from a 32-channel time resolved system used to image the breast" OSA Biomedical Topic Meetings, Miami.

Yusof R Md, J C Hebden, A Gibson, N Everdell, T Austin, J H Meek, S R Arridge, J S Wyatt, D T Delpy (2003). "Validation of the use of homogenous reference phantoms for optical tomography of the neonatal brain" SPIE Proc. "Optical Tomography and Spectroscopy of Tissue V" Vol. 4955, pages 6-11.

Gibson A, R Md Yusof, H Dehghani, J Riley, N Everdell, R Richards, J Hebden, M Schweiger, S Arridge, D T Delpy (2002). "Optical tomography of a realistic head-shaped phantom". OSA Biomedical Topic Meetings, Miami.

Bland T, J Hebden, E M C Hillman, A Gibson, N Everdell, D T Delpy, S R Arridge, M Douek (2002). "Optical Tomography of the breast using a 32-channel time-resolved imager." OSA Biomedical Topic Meetings, Miami.

Hebden J, E M C Hillman, A Gibson, N Everdell, R Yusof, D T Delpy, S R Arridge, T Austin, J H Meek (2002). "Time resolved optical imaging of the newborn infant brain: initial clinical results". OSA Biomedical Topic Meetings, Miami.

Vaithianathan T, I D C Tullis, N Everdell, T Leung, J Meek, D T Delpy (2003): Functional imaging of the brain using a portable NIR instrument, Proceedings of SPIE, San Jose, USA.

Vaithianathan T, I D C Tullis, N Everdell, J Meek, T Austin, D T Delpy (2002): A portable near infrared spectroscopy system for mapping functional activation in infants, 8th International Conference on Functional Mapping of the Human Brain, Sendai, Japan.

PhD

N. Everdell (2001) "A Haemodialysis System for the Treatment of Acute Renal Failure and Metabolic Disorders in Neonates". Middlesex University