David Carmichael

Profile

At present, I work at the Department of clinical and Experimental Epilepsy (DCEE), Institute of Neurology (IoN) as a Senior Research Fellow.

The IoN provides teaching and research of the highest quality in neurology and the neurosciences and has achieved the highest research rating. Within this organisation the department DCEE excels in both basic and clinical scientific research in many complementary disciplines. The role of this MRC funded position is to investigate and improve the efficacy of scalp EEG-fMRI for localisation of epileptic activity and to investigate the feasibility of simultaneous intracranial EEG-fMRI.

Interests

My interests encompass the development of novel neuroimaging techniques, combinations, and applications. My current work is focussed on using functional MRI and electroencephalography (EEG) to better understand epilepsy and how to treat it surgically. I have particular experience in MRI pulse sequence and hardware development as well as MRI safety and am increasingly involved in using new methods to combine and process data from different modalities such as EEG and fMRI.

Publications (last five years) 

2009

Reducing ghosting due to k-space discontinuities in Fast Spin Echo (FSE) imaging by a new combination of K-space ordering and parallel imaging

Carmichael DW, Thomas DL, Ordidge RJ.

Doi: 10.1016/j.jmr.2009.06.013 - In Press

Causal Hierarchy within the Thalamo-Cortical Network in Spike and Wave Discharges

Vaudano A, Laufs H, Kiebel S, Carmichael DW, Hamandi K, Guye M, Thornton R, Rodionov R, Friston K, Duncan J, Lemieux L

PloS One In press

The spatio-temporal mapping of epileptic networks: combination of EEG-fMRI and EEG source imaging

Vulliemoz S, Thornton R, Rodionov R, Carmichael DW, Guye M, Lhatoo S, McEvoy AW, Spinelli L, Michel CM, Duncan JS, Lemieux L.

Neuroimage. 2009 Jul 1;46(3):834-43.

Subpixel enhancement of nonuniform tissue (SPENT): a novel MRI technique for quantifying BMD

Yiannakas MC, Carmichael DW, Farquharson MJ, Ordidge RJ.

J Bone Miner Res. 2009 Feb;24(2):324-33.

PMID: 18767933 [PubMed - in process]

2008

Safety of localizing epilepsy monitoring intracranial electroencephalograph electrodes using MRI: radiofrequency-induced heating

Carmichael DW, Thornton JS, Rodionov R, Thornton R, McEvoy A, Allen PJ, Lemieux L.

J Magn Reson Imaging. 2008 Nov;28(5):1233-44.

PMID: 18972332 [PubMed - indexed for MEDLINE]

An investigation of the relationship between BOLD and perfusion signal changes during epileptic generalised spike wave activity

Carmichael DW, Hamandi K, Laufs H, Duncan JS, Thomas DL, Lemieux L.

Magn Reson Imaging. 2008 Sep;26(7):870-3. Epub 2008 May 22.

PMID: 18501544 [PubMed - indexed for MEDLINE]

Recent advances in recording electrophysiological data simultaneously with magnetic resonance imaging

Laufs H, Daunizeau J, Carmichael DW, Kleinschmidt A.

Neuroimage. 2008 Apr 1;40(2):515-28. Epub 2007 Dec 7. Review.

PMID: 18201910 [PubMed - indexed for MEDLINE]

2007

Greater hypoxia-induced cell death in prenatal brain after bacterial-endotoxin pretreatment is not because of enhanced cerebral energy depletion: a chicken embryo model of the intrapartum response to hypoxia and infection

Wang X, Carmichael DW, Cady EB, Gearing O, Bainbridge A, Ordidge RJ, Raivich G, Peebles DM.

J Cereb Blood Flow Metab. 2008 May;28(5):948-60. Epub 2007 Nov 21.

PMID: 18030303 [PubMed - indexed for MEDLINE]

BOLD and perfusion changes during epileptic generalised spike wave activity

Hamandi K, Laufs H, Nöth U, Carmichael DW, Duncan JS, Lemieux L.

Neuroimage. 2008 Jan 15;39(2):608-18. Epub 2007 Jul 19.

PMID: 17920297 [PubMed - indexed for MEDLINE]

Independent component analysis of interictal fMRI in focal epilepsy: comparison with general linear model-based EEG-correlated fMRI

Rodionov R, De Martino F, Laufs H, Carmichael DW, Formisano E, Walker M, Duncan JS, Lemieux L.

Neuroimage. 2007 Nov 15;38(3):488-500. Epub 2007 Aug 17.

PMID: 17889566 [PubMed - indexed for MEDLINE]

Functional MRI with active, fully implanted, deep brain stimulation systems: safety and experimental confounds

Carmichael DW, Pinto S, Limousin-Dowsey P, Thobois S, Allen PJ, Lemieux L, Yousry T, Thornton JS.

Neuroimage. 2007 Aug 15;37(2):508-17. Epub 2007 May 18.

PMID: 17590355 [PubMed - indexed for MEDLINE]

Noncanonical spike-related BOLD responses in focal epilepsy

Lemieux L, Laufs H, Carmichael D, Paul JS, Walker MC, Duncan JS.

Hum Brain Mapp. 2008 Mar;29(3):329-45.

PMID: 17510926 [PubMed - indexed for MEDLINE]

Modelling large motion events in fMRI studies of patients with epilepsy

Lemieux L, Salek-Haddadi A, Lund TE, Laufs H, Carmichael D.

Magn Reson Imaging. 2007 Jul;25(6):894-901. Epub 2007 May 8.

PMID: 17490845 [PubMed - indexed for MEDLINE]

2006

Improving whole brain structural MRI at 4.7 Tesla using 4 irregularly shaped receiver coils

Carmichael DW, Thomas DL, De Vita E, Fernández-Seara MA, Chhina N, Cooper M, Sunderland C, Randell C, Turner R, Ordidge RJ.

Neuroimage. 2006 Sep;32(3):1176-84. Epub 2006 Jun 27.

PMID: 16806980 [PubMed - indexed for MEDLINE]

2005

Common SENSE (sensitivity encoding using hardware common to all MR scanners): a new method for single-shot segmented echo planar imaging

Carmichael DW, Priest AN, De Vita E, Ordidge RJ.

Magn Reson Med. 2005 Aug;54(2):402-10.

PMID: 16032675 [PubMed - indexed for MEDLINE]