Adrien Desjardins




Room 3.03
Dept. Medical Physics and Bioengineering
Malet Place Engineering Building
University College London
Gower Street

Contact details

Room number:
Email address
+44 (0)20 7679 0300
+44 (0)20 7679 0255


  • Ph.D. (Biophysics; Medical Engineering and Medical Physics) Harvard University and Harvard-MIT Division of Health Sciences and Technology, Boston, USA (2007)
  • B.Sc. (Mathematics and Physics), University of British Columbia, Vancouver, Canada (2001)

Research Interests

  • Medical devices and image-guided interventions
  • Optical coherence tomography
  • Confocal laser scanning microscopy
  • Optical spectroscopy
  • E-learning in science and medicine

Non-Research Activities


  • Desjardins AE, Hendriks BHW, van der Voort M, Nachabé R, Bierhoff W, Braun G, Babic D, Rathmell JP, Holmin S, Söderman M, Holmström B. Epidural needle with embedded optical fibers for spectroscopic differentiation of tissue: ex vivo feasibility study. Biomedical Optics Express. 2011;2(6):1452-61.
  • Hendriks BH, Bierhoff WC, Horikx JJL, Desjardins AE, Hezemans CA, 't Hooft GW, Lucassen GW, Mihajlovic N.  High-resolution resonant and nonresonant fiber-scanning confocal microscope. Journal of Biomedical Optics. 2011;16(2):026007.
  • Rathmell JP, Desjardins AE, van der Voort M, Hendriks BH, Nachabé R, Roggeveen S, Babic D, Söderman M, Brynolf M, Holmström B. Identification of the Epidural Space with Optical Spectroscopy: An In Vivo Swine Study. Anesthesiology. 2010;113(6):1406-18.
  • Nachabé R, Hendriks BHW, van der Voort M, Desjardins AE, Sterenborg HJCM.  Estimation of biological chromophores using diffuse optical spectroscopy: benefit of extending the UV-VIS wavelength range to include 1000 to 1600 nm. Biomedical Optics Express. 2010;1(5):1432-42.
  • Nachabé R, Hendriks BHW, Desjardins AE, van der Voort M, van der Mark MB, Sterenborg HJCM. Estimation of lipid and water concentrations in scattering media with diffuse optical spectroscopy from 900 to 1600 nm. Journal of Biomedical Optics. 2010;15(3):037015.
  • Desjardins AE, Vakoc BJ, Suter MJ, Yun S-H, Tearney GJ, Bouma BE. Real-time FPGA Processing for High-Speed Optical Frequency Domain Imaging. IEEE Transactions on Medical Imaging. 2009;28(9):1468-72.
  • Boudoux C, Leuin SC, Oh WY, Suter MJ, Desjardins AE, Vakoc BJ, Bouma BE, Hartnick CJ, Tearney GJ. Optical microscopy of the pediatric vocal fold. Archives of Otolaryngology. 2009;135(1):53-64.
  • Tearney GJ, Waxman S, Shishkov M, Vakoc BJ, Suter MJ, Freilich MI, Desjardins AE, Oh WY, Bartlett LA, Rosenberg M, Bouma BE. Three-Dimensional Coronary Artery Microscopy by Intracoronary Optical Frequency Domain Imaging. Journal of the American College of Cardiology: Cardiovascular Imaging. 2008;1(6):752-61.
  • Oh WY, Yun SH, Vakoc BJ, Shishkov M, Desjardins AE, Park BH, de Boer JF, Tearney GJ, Bouma BE. High-speed polarization sensitive optical frequency domain imaging with frequency multiplexing. Optics Express. 2008;16(2):1096-103.
  • Desjardins AE, Vakoc BJ, Tearney GJ, Bouma BE. Backscattering Spectroscopic Contrast with Angle-Resolved Fourier Domain OCT. Optics Letters. 2007;32(21):3158-60.
  • Ozcan A, Bilenca A, Desjardins AE, Bouma BE, Tearney GJ. Speckle reduction in optical coherence tomography images using digital filtering. Journal of the Optical Society of America A. 2007;24(7):1901-10.
  • Desjardins AE, Vakoc BJ, Oh WY, Nezam SMRM, Tearney GJ, Bouma BE. Angle-resolved Optical Coherence Tomography with sequential angular selectivity for speckle reduction. Optics Express. 2007;15(10):6200-9.
  • Nezam SMRM, Vakoc BJ, Desjardins AE, Tearney GJ, Bouma BE. Increased ranging depth in optical frequency domain imaging by frequency encoding. Optics Letters. 2007;32(9):2768-70.
  • Vakoc BJ, Shishkov M, Yun SH, Oh WY, Suter MJ, Desjardins AE, Evans JA, Nishioka NS, Tearney GJ, Bouma BE. Comprehensive esophageal microscopy by using optical frequency-domain imaging (with video). Gastrointestinal Endoscopy. 2007;65(6):898-905.
  • Desjardins AE, Vakoc BJ, Bilenca A, Tearney GJ, Bouma BE. Estimation of the Scattering Coefficients of Turbid Media using Angle-Resolved Optical Frequency-Domain Imaging. Optics Letters. 2006;32(11):1560-2.
  • Yun SH, Tearney GJ, Vakoc BJ, Shishkov M, Oh WY, Desjardins AE, Suter MJ, Chan RC, Evans JA, Jang I-K, Nishioka NS, de Boer JF, Bouma BE. Comprehensive volumetric optical microscopy in vivo. Nature Medicine. 2006;12(12):1429-33.
  • Desjardins AE, Vakoc BJ, Tearney GJ, Bouma BE. Speckle Reduction in OCT using Massively-Parallel Detection and Frequency-Domain Ranging. Optics Express. 2006;14(11):4736-45.
  • Desjardins AE. Angularly Resolved Backscattering of Light from Turbid Suspensions of Dielectric Spheres. Journal of Quantitative Spectroscopy and Radiative Transfer. 2006;102(2):139-51.
  • Bilenca A, Desjardins AE, Bouma BE, Tearney GJ. Multicanonical Monte-Carlo simulations of light propagation in biological media. Optics Express. 2005;13(24):9822-33.
  • Tunnell JW, Desjardins AE, Galindo L, Georgakoudi I, McGee SA, Mirkovic J, Mueller MG, Nazemi J, Nguyen FT, Wax A, Zhang QG, Dasari RR, Feld MS. Instrumentation for multi-modal spectroscopic diagnosis of epithelial dysplasia. Technology in Cancer Research and Treatment. 2003;2(6):505-14.
  • Desjardins AE, Li Y-X, Reinker S, Miura RM, Neuman RS. The Influences of I-h on Temporal Summation in Hippocampal CA1 Pyramidal Neurons: A Modeling Study. Journal of Computational Neuroscience. 2003;15(2):131-42.
  • Desjardins AE, Kiehl KA, Liddle PF. Removal of confounding effects of global signal in functional MRI analyses. Neuroimage. 2001;13(4):751-58.
  • Percy JR, Desjardins AE, Yu L, Landis HJ. Small-amplitude red variables in the AAVSO photoelectric program: Light curves and periods. Publications of the Astronomical Society of the Pacific. 1996;108:139-45.
  • Percy JR, Desjardins AE. Pulsation mode switching in the small-amplitude red variable W Bootis. Publications of the Astronomical Society of the Pacific. 1996;108:847-50.