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THE ADVANCED MAGNETIC RESONANCE IMAGING GROUP
Nuclear Magnetic Resonance (NMR) involves the measurement of radiofrequency signals arising from transitions between nuclear energy states that are formed when spinning nuclei align with an applied magnetic field. In Magnetic Resonance Imaging (MRI) it is the spatial distribution of protons (eg. hydrogen nuclei and hence water) that are mapped in the 2 or 3 dimensional image. In Magnetic Resonance Spectroscopy (MRS), the concentration of important metabolites are measured in the body, usually from a well defined rectangular volume located relative to the MR image. In both cases, the technique is non-invasive and can be applied repetitively with no harm to the patient. MR scanners are costly (up to several million dollars/pounds) and incorporate a powerful magnet which is usually superconducting.
Who we Are
Research at AMRIG
At AMRIG we have projects that are split amongst several different imaging systems. For human imaging we have a 3 Tesla Siemens Trio, and for pre-clinical imaging we work closely with groups at the Insitute of Neurology (IoN) and the Centre for Advanced Biomedical Imaging (CABI), using their 9.4 Tesla Varian scanners.
The Siemens 3T TRIO scanner in the UCL High Field laboratory was established with grants from the Wellcome Trust and the Brain Research Trust in September 2005, and the facility is led by Prof Roger Ordidge. The concept was for the new facility to accommodate brain imaging projects led by two groups: the Advanced MRI Group (AMRIG) and the Wellcome Trust Centre for Neuroimaging (WTCN). AMRIG is made up of PIs from a number of different UCL MRI groupings including investigators from the UCL Department of Medical Physics and Bioengineering and the UCL Institute of Neurology (ION). A significant proportion of research projects from both groups is patient-based, and draws on the large number of patients treated in our partner hospital, the National Hospital for Neurology and Neurosurgery (UCLH NHS Trust) and the expertise of the NHNN Department of Neuroradiology. The TRIO facility provides a UCL-wide clinical research platform which benefits from the considerable neuroimaging expertise across UCL.
MRI methodologies available at AMRIG
Our research is split into:
Providing scientific support for clinical research projects.
Methods development on human and pre-clinical imaging systems.
Hardware development of radiofrequency (RF) coils
Magnetic Resonance at UCL
NMR is a well established and very flexible modality that has applications in many fields, and consequently there are several groups at UCL that actively use NMR techniques as part of their research
David Carmichael has won the 2009 UCL Centre for Neuroimaging Techniques Investigator of the Year award, in recognition of his work recording electrical data from the brain whilst performing Magnetic Resonance Imaging (MRI). More...
Published: Aug 25, 2010 12:21:48 PM
Our research publications are listed here.