Key Publications

1 Mercer,P.F., Johns,R.J., Scotton,C.J., Krupiczojc,M.A., Howell,D.C.J., Koenigshoff,M., McAnulty,R.J., Das,A., Thorley,A.J., Tetley,T.D., Eickelberg,O., Chambers,R.C. (2009). Pulmonary epithelium is a prominent source of proteinase-activated receptor-1-inducible CCL2 in pulmonary fibrosis. American Journal of Respiratory and Critical Care Medicine 179(5), 414-425. ISSN: 1073-449X PubMed link
2 Scotton,C.J., Krupiczojc,M.A., Koenigshoff,M., Mercer,P.F., Lee,Y.C.G., Kaminski,N., Morser,J., Post,J.M., Maher,T.M., Nicholson,A.G, Moffatt,J.D., Laurent,G.J., Derian,C.K., Eickelberg,O., Chambers,R.C (2009). Increased local expression of coagulation factor X contributes to the fibrotic response in human and murine lung injury. Journal of Clinical Investigation 119(9), 2550-2563. ISSN: 0021-9738
3 Deng,X., Mercer,P.F., Scotton,C.J., Gilchrist,A., Chambers,R.C. (2008). Thrombin induces fibroblast CCL2/JE production and release via coupling of PAR1 to Gαq and cooperation between ERK1/2 and Rho kinase signaling pathways. Molecular Biology of the Cell 19(6), 2520-2533. ISSN: 1059-1524
4 Mercer P.F., Johns R.H., Scotton C.J., Krupiczojc M.A., Königshoff M., Howell D.C., McAnulty R.J., Das A., Thorley A.J., Tetley T.D., Eickelberg O., Chambers R.C. Pulmonary epithelium is a prominent source of proteinase-activated receptor-1-inducible CCL2 in pulmonary fibrosis. Am J Respir Crit Care Med. 2009. 179(5):414-25.
5 Scotton, C.J., and Chambers, R.C. Molecular targets in pulmonary fibrosis: the myofibroblast in focus. Chest. 2007. 132(4):1311-21.
6.
Scotton, C.J., Martinez, F.O., Smelt, M.J., Sironi, M., Locati, M., Mantovani, A., and Sozzani, S. Transcriptional profiling reveals complex regulation of the monocyte IL-1β system by IL-13. J Immunol. 2005. 174(2):834-845.