Core Facilities

CABI - The Centre for Advanced Biomedical Imaging

The Centre for Advanced Biomedical Imaging (CABI), based in the Paul O’Gorman building on Huntley Street, provides state-of-the-art high-field magnetic resonance imaging (MRI), a new Photoacoustic Imaging facility, Optical Projection Tomography, Light-Sheet Imaging, Ultrasound, Bioluminescence and Fluorescence imaging, Confocal Endoscopy, as well as SPECT/CT and  PET/MRI/CT. The Centre is ideally suited for cross-disciplinary work in neuroscience, cardiovascular biology and oncology. For more information and contact details click on the following links:

Wolfson Institute for Biomedical Research
Perkin Elmer Spinning Disk Confocal
The Perkin Elmer's revolutionary spinning-disk technology allows the system to scan the sample faster than any other available system - 1,000 times per second - yet provides superior image quality due to greater image averaging and a cooled ECCD camera.
Leica TCS SP2 Confocal Microscope
The Leica functions as a 3-colour, UV and visible confocal microscope in one system, utilizing fiber coupled UV, VIS and IR lasers (allowing rapid switching between laser-firing). There is even a “Design-a-filter” application for ultimate flexibility, or new dyes and difficult dye combinations, and allows easy wavelength selection from pre-programmed spectra of all popular dyes.
CyAn ADP FACS Analyser
The CyAn ADP High-Performance Flow Cytometer is a state-of-the-art flow cytometer that utilizes multiple laser excitation sources to analyze biological cells, beads, or other microscopic particles. It remains a closed fluidic system – also allowing analysis of biohazardous samples (such as human blood samples, bacteria, etc), with appropriate precautions and authorization.
Speciality Support Station Includes:

Flow Cytometry

Summit 4.3
Specialty Software Workstation
Kaluza v1.2

Imaging

Volocity (Quantification and Visualisation)
Axiovision Rel 4.7
MacBiophotonics Image J

Genomics

Sequence scanner v1.0
Partek Genommics Suite 6.6
Partek Genommics Suite 6.6 Beta
CLC Genomics Workbench 4

Miscellaneous

SeaHorse xF24

All enquiries should be directed to the Applications Specialist (Microscopy & FACS) Robert Francis 020 7679 6895 (ext. 46895) from 18th August.  Until then, please contact Alison Kelly

 
Royal Free Campus
Centre for Biomedical Science (CBS) This centre comprises expert staff and platforms for Advanced Microscopy, Proteomics and Transgenics and prioritises collaborations with investigators located on the Royal Free Campus.

Major platforms include confocal microscopes, UPLC-Orbitrap/ETD and MALDI-TOF/TOF mass spectrometers, and plasmid micro-injection stages. All three units offer advice for project design, costing and grant application, operate on a cost recovery basis, and welcome new collaborations in translational biomedical research.

Contact Prof Justin Hsuan for further details j.hsuan@ucl.ac.uk
Electron Microscopy Unit
The Electron Microscopy Unit, based at UCL’s Royal Free Campus (Lower Ground Floor), has been delivering an excellent service to clinicians and academics for almost 40 years.  The Unit offers high quality transmission and scanning electron microscopy, x-ray microanalysis and immune-electron microscopy expertise. The service is open to all users within and outside UCL.  For further details please contact Innes Clatworthy, EM Unit Manager (i.clatworthy@ucl.ac.uk).
Rayne Building
Flow cytometry

The flow cytometry facility is a fully-managed state-of-the-art centre with of 5 analysers, a high speed cell sorter and ImagestreamX Mk2 imaging flow cytometer. (see equipment).

All enquiries for training and registration to use the facility should be made to the core facility manager, Jamie Evans, jamie.evans@ucl.ac.uk  tel: 020 3108 2174

Tissue Culture
The Rayne Tissue Culture suite is a fully managed facility for culture of primary cells and cell lines, equipped with 9 class 2 cabinets and 17 CO2 incubators, bench-top and microcentrifuges, microscopes, and other supporting equipment. New users should contact the facility manager, Jutta Palmen, to arrange an induction session, and for further information: Jutta Palmen j.palmen@ucl.ac.uk Tel: 020 7679 6977 (Ext 46977)
Organ bath and myography
This facility is equipped for measurement of vascular and gastrointestinal contractility and reactivity using organ bath and wire myography in tissues from a range of species including mice, humans and rat.

For more information and to arrange training sessions, contact Professor Lucie Clapp l.clapp@ucl.ac.uk Tel 020 7679 6180 (Ext 46180)
Washup and autoclaving
A service is provided for washing glassware and autoclave sterilisation of glassware and liquid media for microbiological or cell culture.  For more information, contact Stephen McElvaney s.mcelvaney@ucl.ac.uk
Cell Imaging
A part-managed facility containing a Zeiss Axioskop 2 fluorescent microscope linked to computer controlled colour and black & white cameras. Also available are a Typhoon 8600 variable mode imager, for imaging gels/membranes using chemiluminescence, fluorescence or phosphor, and DIGE imaging of cy- labelled proteins with software for proteomic analysis. These facilities are available through a booking system at low cost. For information on cost and to arrange access, contact Dr Shanie Budhram-Mahadeo (v.budhram-mahadeo@ucl.ac.uk) or Dr Ian Evans (i.evans@ucl.ac.uk).

Page last modified on 11 nov 14 10:35