Staff Profile

UCL Division of Medicine

Staff Profile

Prof William Mckenna

Personal Profile

Name:	William Mckenna	Email:	w.mckenna@ucl.ac.uk
Title:	Prof	Tel:	0203 456 4502
Department:	Centre for Cardiology in the Young	Fax:	0203 456 4901
Position:	Professor of Cardiology	Address:	16-18 Westmoreland Street, , London, W1G 8PH
Research Domain:	Cardiometabolic Science, Global Health	Web Page:

Profile

Research Description

At UCL there are 22 centres of cardiovascular related medicine. At the recommendation of the recent biomedicine review the Institute of Cardiovascular Science (ICS) has been established to enable coordination of research, training, funding and governance across UCL and its affiliated hospitals. Research themes from ‘Birth to Grave’ have been mapped for ICS West (UCLH) and ICS East (GOSH) with the overall aim to translate scientific discovery and innovation into measurable improvements in cardiovascular health.

Research Activities

Paediatric Neurology

Education Description

UCL Collaborators

Prof Adrian Thrasher; Prof Michael Duchen; Prof Mary Reilly; Prof Francesco Muntoni; Prof Perry Elliott; Dr Jenny Morgan

External Collaborators

Publications

2013

Hodgkinson KA, Connors SP, Merner N, Haywood A, Young T-L, McKenna WJ, Gallagher B, Curtis F, Bassett AS, Parfrey PS (2013). The natural history of a genetic subtype ofarrhythmogenic right ventricular cardiomyopathy caused by a p.S358L mutation in TMEM43. CLINICAL GENETICS, 83(4), 321 - 331. doi:10.1111/j.1399-0004.2012.01919.x
Bayliss CR, Jacques AM, Leung M-C, Ward DG, Redwood CS, Gallon CE, Copeland O, McKenna WJ, dos Remedios C, Marston SB, Messer AE (2013). Myofibrillar Ca2+ sensitivity is uncoupled from troponin I phosphorylation in hypertrophic obstructive cardiomyopathy due to abnormal troponin T. CARDIOVASCULAR RESEARCH, 97(3), 500 - 508. doi:10.1093/cvr/cvs322
O'Mahony C, Tome-Esteban M, Lambiase PD, Pantazis A, Dickie S, McKenna WJ, Elliott PM (2013). A validation study of the 2003 American College of Cardiology/European Society of Cardiology and 2011 American College of Cardiology Foundation/American Heart Association risk stratification and treatment algorithms for sudden cardiac death in patients with hypertrophic cardiomyopathy.. Heart, 99(8), 534 - 541. doi:10.1136/heartjnl-2012-303271
Coats CJ, Gallagher MJ, Foley M, O'Mahony C, Critoph C, Gimeno J, Dawnay A, McKenna WJ, Elliott PM (2013). Relation between serum N-terminal pro-brain natriuretic peptide and prognosis in patients with hypertrophic cardiomyopathy.. Eur Heart J, , - . doi:10.1093/eurheartj/eht070
Lopes LR, Zekavati A, Syrris P, Hubank M, Giambartolomei C, Dalageorgou C, Jenkins S, McKenna W, Uk10k Consortium , Plagnol V, Elliott PM (2013). Genetic complexity in hypertrophic cardiomyopathy revealed by high-throughput sequencing.. J Med Genet, 50(4), 228 - 239. doi:10.1136/jmedgenet-2012-101270
Quarta G, Husain SI, Flett AS, Sado DM, Chao CY, Tomé Esteban MT, McKenna WJ, Pantazis A, Moon JC (2013). Arrhythmogenic right ventricular cardiomyopathy mimics: role of cardiovascular magnetic resonance.. J Cardiovasc Magn Reson, 15, 16 - . doi:10.1186/1532-429X-15-16

2012

Pasquale F, Syrris P, Kaski JP, Mogensen J, McKenna WJ, Elliott P (2012). Long-term outcomes in hypertrophic cardiomyopathy caused by mutations in the cardiac troponin T gene. Circulation. Cardiovascular Genetics, 5(1), 10 - 17.
O'Mahony C, Lambiase PD, Quarta G, Cardona M, Calcagnino M, Tsovolas K, Al-Shaikh S, Rahman SM, Arnous S, Jones S, McKenna W, Elliott P (2012). The long-term survival and the risks and benefits of implantable cardioverter defibrillators in patients with hypertrophic cardiomyopathy.. Heart, 98(2), 116 - 125. doi:10.1136/hrt.2010.217182
Coats CJ, Patel A, Mist B, Tome M, Dickie S, McKenna WJ, Elliott PM (2012). Sub-maximal exercise parameters are important prognostic markers in hypertrophic cardiomyopathy.
O'Mahony C, Tome-Esteban M, Pantazis A, Dickie S, McKenna W, Elliott P (2012). Validation of the 2003 ACC/ESC guidelines on the risk stratification of sudden cardiac death in hypertrophic cardiomyopathy.
O'Mahony C, Rahman S, Biagini E, Rappezzi C, Monseratt L, Gimeno JR, Limongelli G, Anastasakis A, McKenna W, Elliott P (2012). A novel clinical risk prediction model for sudden cardiac death in hypertrophic cardiomyopathy: a proof of concept study.
Caforio ALP, Zachara E, Re F, Baratta P, Schiavo A, Thiene G, Iliceto S, Syrris P, McKenna WJ (2012). Involvement of autoimmunity in arrhythmogenic right ventricular cardiomyopathy: serum anti-intercalated disk autoantibodies are associated with desmosomal gene mutations.
Sen-Chowdhry S, Tomé Esteban MT, McKenna WJ (2012). Insights and challenges in hypertrophic cardiomyopathy, 2012.. Herzschrittmacherther Elektrophysiol, 23(3), 174 - 185. doi:10.1007/s00399-012-0227-5
Sado DM, Flett AS, Banypersad SM, White SK, Maestrini V, Quarta G, Lachmann RH, Murphy E, Mehta A, Hughes DA, McKenna WJ, Taylor AM, Hausenloy DJ, Hawkins PN, Elliott PM, Moon JC (2012). Cardiovascular magnetic resonance measurement of myocardial extracellular volume in health and disease.. Heart, 98(19), 1436 - 1441. doi:10.1136/heartjnl-2012-302346
Sen-Chowdhry S, Jacoby D, McKenna WJ (2012). The implications of inheritance for clinical management.. Circ Cardiovasc Genet, 5(4), 467 - 476. doi:10.1161/CIRCGENETICS.110.959361
Moon JC, McKenna WJ (2012). Myocardial crypts: a prephenotypic marker of hypertrophic cardiomyopathy?. Circ Cardiovasc Imaging, 5(4), 431 - 432. doi:10.1161/CIRCIMAGING.112.975888
Kaski JP, Syrris P, Shaw A, Alapi KZ, Cordeddu V, Esteban MT, Jenkins S, Ashworth M, Hammond P, Tartaglia M, McKenna WJ, Elliott PM (2012). Prevalence of sequence variants in the RAS-mitogen activated protein kinase signaling pathway in pre-adolescent children with hypertrophic cardiomyopathy.. Circ Cardiovasc Genet, 5(3), 317 - 326. doi:10.1161/CIRCGENETICS.111.960468
Lambiase PD, Nunn LM, Bhar-Amato J, Lowe MD, Macfarlane PW, Rogers P, McKenna WJ, Elliott PM (2012). Reply.. J Am Coll Cardiol, 59(18), 1660 - 1661. doi:10.1016/j.jacc.2012.01.031
Ramon Gimeno J, Teresa Tome M, McKenna WJ (2012). Alcohol Septal Ablation in Hypertrophic Cardiomyopathy: An Opportunity to Be Taken. REVISTA ESPANOLA DE CARDIOLOGIA, 65(4), 314 - 318. doi:10.1016/j.rec.2011.11.014
Jacoby DL, DePasquale EC, Lour O, Pomianowski P, McKenna WJ (2012). Familial Dilated Cardiomyopathy (FDCM) Prevalence in End-Stage Non-Ischemic Heart Failure (ESHF).
DePasquale EC, Dries D, McKenna WJ, Jacoby DL (2012). Outcomes of Familial Dilated Cardiomyopathy (FDCM) Post Heart Transplant (HT).
Sen-Chowdhry S, McKenna WJ (2012). Sudden death from genetic and acquired cardiomyopathies.. Circulation, 125(12), 1563 - 1576. doi:10.1161/CIRCULATIONAHA.111.025528
Sniderman JD, Sado DM, Sniderman AD, McKenna WJ (2012). Evaluation of suspected right ventricular pathology in the athlete.. Prog Cardiovasc Dis, 54(5), 397 - 406. doi:10.1016/j.pcad.2012.01.005
Jacoby D, McKenna WJ (2012). Genetics of inherited cardiomyopathy. EUROPEAN HEART JOURNAL, 33(3), 296 - U163. doi:10.1093/eurheartj/ehr260
Page SP, Kounas S, Syrris P, Christiansen M, Frank-Hansen R, Andersen PS, Elliott PM, McKenna WJ (2012). Cardiac myosin binding protein-C mutations in families with hypertrophic cardiomyopathy: disease expression in relation to age, gender, and long term outcome.. Circ Cardiovasc Genet, 5(2), 156 - 166. doi:10.1161/CIRCGENETICS.111.960831
Gomes J, Finlay M, Ahmed AK, Ciaccio EJ, Asimaki A, Saffitz JE, Quarta G, Nobles M, Syrris P, Chaubey S, McKenna WJ, Tinker A, Lambiase PD (2012). Electrophysiological abnormalities precede overt structural changes in arrhythmogenic right ventricular cardiomyopathy due to mutations in desmoplakin-A combined murine and human study.. Eur Heart J, 33(15), 1942 - 1953. doi:10.1093/eurheartj/ehr472
Quarta G, Syrris P, Ashworth M, Jenkins S, Zuborne Alapi K, Morgan J, Muir A, Pantazis A, McKenna WJ, Elliott PM (2012). Mutations in the Lamin A/C gene mimic arrhythmogenic right ventricular cardiomyopathy.. Eur Heart J, 33(9), 1128 - 1136. doi:10.1093/eurheartj/ehr451
O'Mahony C, Lambiase PD, Rahman SM, Cardona M, Calcagnino M, Quarta G, Tsovolas K, Al-Shaikh S, McKenna W, Elliott P (2012). The relation of ventricular arrhythmia electrophysiological characteristics to cardiac phenotype and circadian patterns in hypertrophic cardiomyopathy.. Europace, 14(5), 724 - 733. doi:10.1093/europace/eur362
Gehmlich K, Syrris P, Reimann M, Asimaki A, Ehler E, Evans A, Quarta G, Pantazis A, Saffitz JE, McKenna WJ (2012). Molecular changes in the heart of a severe case of arrhythmogenic right ventricular cardiomyopathy caused by a desmoglein-2 null allele.. Cardiovasc Pathol, 21(4), 275 - 282. doi:10.1016/j.carpath.2011.09.005
Bayés de Luna A, Brugada J, Baranchuk A, Borggrefe M, Breithardt G, Goldwasser D, Lambiase P, Riera AP, Garcia-Niebla J, Pastore C, Oreto G, McKenna W, Zareba W, Brugada R, Brugada P (2012). Current electrocardiographic criteria for diagnosis of Brugada pattern: a consensus report.. J Electrocardiol, 45(5), 433 - 442. doi:10.1016/j.jelectrocard.2012.06.004

2011

McKenna W, Elliott P (2011). Diseases of the myocardium and endocardium. In Goldman L, Schaffer AI (Ed.), Cecil Medicine (pp. 318 - 333). : Saunders Elsevier.
Caforio AL, Zachara E, Re F, Baratta P, Bagato F, Thiene G, Iliceto S, Syrris P, McKenna WJ (2011). Serum Anti-Intercalated Disk Autoantibodies in Arrhythmogenic Right Ventricular Cardiomyopathy are Autoimmune Markers Associated with Pathogenic Desmosomal Mutations. CIRCULATION, 124(21), - .
Tripathi S, Schultz I, Becker E, Montag J, Borchert B, Francino A, Navarro-Lopez F, Perrot A, Oezcelik C, Osterziel K-J, McKenna WJ, Brenner B, Kraft T (2011). Unequal allelic expression of wild-type and mutated beta-myosin in familial hypertrophic cardiomyopathy. BASIC RESEARCH IN CARDIOLOGY, 106(6), 1041 - 1055. doi:10.1007/s00395-011-0205-9
Asimaki A, Tandri H, Duffy ER, Winterfield JR, Mackey-Bojack S, Picken MM, Cooper LT, Wilber DJ, Marcus FI, Basso C, Thiene G, Tsatsopoulou A, Protonotarios N, Stevenson WG, McKenna WJ, Gautam S, Remick DG, Calkins H, Saffitz JE (2011). Altered Desmosomal Proteins in Granulomatous Myocarditis and Potential Pathogenic Links to Arrhythmogenic Right Ventricular Cardiomyopathy. CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, 4(5), 743 - U240. doi:10.1161/CIRCEP.111.964890
Ackerman MJ, Priori SG, Willems S, Berul C, Brugada R, Calkins H, Camm AJ, Ellinor PT, Gollob M, Hamilton R, Hershberger RE, Judge DP, Le Marec H, McKenna WJ, Schulze-Bahr E, Semsarian C, Towbin JA, Watkins H, Wilde A, Wolpert C, Zipes DP (2011). HRS/EHRA Expert Consensus Statement on the State of Genetic Testing for the Channelopathies and Cardiomyopathies. HEART RHYTHM, 8(8), 1308 - 1339. doi:10.1016/j.hrthm.2011.05.020
Gehmlich K, Syrris P, Peskett E, Evans A, Ehler E, Asimaki A, Anastasakis A, Tsatsopoulou A, Vouliotis AI, Stefanadis C, Saffitz JE, Protonotarios N, McKenna WJ (2011). Mechanistic insights into arrhythmogenic right ventricular cardiomyopathy caused by desmocollin-2 mutations.. Cardiovasc Res, 90(1), 77 - 87. doi:10.1093/cvr/cvq353
Nunn LM, Bhar-Amato J, Lowe MD, Macfarlane PW, Rogers P, McKenna WJ, Elliott PM, Lambiase PD (2011). Prevalence of J-point elevation in sudden arrhythmic death syndrome families.. J Am Coll Cardiol, 58(3), 286 - 290. doi:10.1016/j.jacc.2011.03.028
Ashrafian H, McKenna WJ, Watkins H (2011). Disease Pathways and Novel Therapeutic Targets in Hypertrophic Cardiomyopathy. CIRC RES, 109(1), 86 - 96. doi:10.1161/CIRCRESAHA.111.242974
Quarta G, Muir A, Pantazis A, Syrris P, Gehmlich K, Garcia-Pavia P, Ward D, Sen-Chowdhry S, Elliott PM, McKenna WJ (2011). Familial evaluation in arrhythmogenic right ventricular cardiomyopathy: impact of genetics and revised task force criteria.. Circulation, 123(23), 2701 - 2709. doi:10.1161/CIRCULATIONAHA.110.976936
Desai MY, Ommen SR, McKenna WJ, Lever HM, Elliott PM (2011). Imaging phenotype versus genotype in hypertrophic cardiomyopathy.. Circ Cardiovasc Imaging, 4(2), 156 - 168. doi:10.1161/CIRCIMAGING.110.957936
Gehmlich K, Lambiase PD, Asimaki A, Ciaccio EJ, Ehler E, Syrris P, Saffitz JE, McKenna WJ (2011). A novel desmocollin-2 mutation reveals insights into the molecular link between desmosomes and gap junctions.. Heart Rhythm, 8(5), 711 - 718. doi:10.1016/j.hrthm.2011.01.010
Ackerman MJ, Priori SG, Willems S, Berul C, Brugada R, Calkins H, Camm AJ, Ellinor PT, Gollob M, Hamilton R, Hershberger RE, Judge DP, Le Marec H, McKenna WJ, Schulze-Bahr E, Semsarian C, Towbin JA, Watkins H, Wilde A, Wolpert C, Zipes DP (2011). HRS/EHRA Expert Consensus Statement on the State of Genetic Testing for the Channelopathies and Cardiomyopathies. EUROPACE, 13(8), 1077 - 1109. doi:10.1093/europace/eur245

2010

Syrris P, McKenna WJ (2010). Arrhythmogenic right ventricular cardiomyopathy. In Kumar D (Ed.), Principles and Practice of Clinical Cardiovascular Genetics (pp. 213 - 226). : Oxford University Press.
Corrado D, Pelliccia A, Heidbuchel H, Sharma S, Link M, Basso C, Biffi A, Buja G, Delise P, Gussac I, Anastasakis A, Borjesson M, Bjornstad HH, Carre F, Deligiannis A, Dugmore D, Fagard R, Hoogsteen J, Mellwig KP, Panhuyzen-Goedkoop N, Solberg E, Vanhees L, Drezner J, Estes NAM, Iliceto S, Maron BJ, Peidro R, Schwartz PJ, Stein R, Thiene G, Zeppilli P, McKenna WJ, European Assoc Cardiovasc Preventi , European Soc Cardiology (2010). Recommendations for interpretation of 12-lead electrocardiogram in the athlete. EUR HEART J, 31(2), 243 - 259. doi:10.1093/eurheartj/ehp473
Potter SLP, Holmqvist F, Platonov PG, Steding K, Arheden H, Pahlm O, Starc V, McKenna WJ, Schlegel TT (2010). Detection of hypertrophic cardiomyopathy is improved when using advanced rather than strictly conventional 12-lead electrocardiogram. J ELECTROCARDIOL, 43(6), 713 - 718. doi:10.1016/j.jelectrocard.2010.08.010
Charron P, Arad M, Arbustini E, Basso C, Bilinska Z, Elliott P, Helio T, Keren A, McKenna WJ, Monserrat L, Pankuweit S, Perrot A, Rapezzi C, Ristic A, Seggewiss H, van Langen I, Tavazzi L (2010). Genetic counselling and testing in cardiomyopathies: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases. EUR HEART J, 31(22), 2715 - 2728B. doi:10.1093/eurheartj/ehq271
Hoskins AC, Jacques A, Bardswell SC, McKenna WJ, Tsang V, dos Remedios CG, Ehler E, Adams K, Jalilzadeh S, Avkiran M, Watkins H, Redwood C, Marston SB, Kentish JC (2010). Normal passive viscoelasticity but abnormal myofibrillar force generation in human hypertrophic cardiomyopathy. J MOL CELL CARDIOL, 49(5), 737 - 745. doi:10.1016/j.yjmcc.2010.06.006
Corrado D, Calkins H, Link MS, Leoni L, Favale S, Bevilacqua M, Basso C, Ward D, Boriani G, Ricci R, Piccini JP, Dalal D, Santini M, Buja G, Iliceto S, Estes NAM, Wichter T, McKenna WJ, Thiene G, Marcus FI (2010). Prophylactic Implantable Defibrillator in Patients With Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia and No Prior Ventricular Fibrillation or Sustained Ventricular Tachycardia. CIRCULATION, 122(12), 1144 - 1152. doi:10.1161/CIRCULATIONAHA.109.913871
Delmar M, McKenna WJ (2010). The Cardiac Desmosome and Arrhythmogenic Cardiomyopathies From Gene to Disease. CIRC RES, 107(6), 700 - 714. doi:10.1161/CIRCRESAHA.110.223412
O'Hanlon R, Grasso A, Roughton M, Moon JC, Clark S, Wage R, Webb J, Kulkarni M, Dawson D, Sulaibeekh L, Chandrasekaran B, Bucciarelli-Ducci C, Pasquale F, Cowie MR, McKenna WJ, Sheppard MN, Elliott PM, Pennell DJ, Prasad SK (2010). Prognostic significance of myocardial fibrosis in hypertrophic cardiomyopathy.. J Am Coll Cardiol, 56(11), 867 - 874. doi:10.1016/j.jacc.2010.05.010
Gehmlich K, Lambiase P, Syrris P, Mckenna WJ (2010). A novel mutation in desmocollin-2 reveals a functional link between desmosomes and gap junctions.
Nunn LM, Bhar-Amato J, Lowe MD, Elliott PM, Mckenna WJ, Lambiase PD (2010). Clinical characteristics and referral patterns of the Brugada population in a UK tertiary cardiac centre.
Finegold J, Giunti P, Mckenna W, Elliott P, Pantazis A (2010). Description of the cardiomyopathy associated with friedreich's ataxia.
Pasquale F, Syrris P, Quarta G, Mahony CO, Tome-Esteban MT, Pantazis A, Kaski JP, McKenna WJ, Elliott PM (2010). Long-term outcomes in hypertrophic cardiomyopathy caused by mutations in the cardiac troponin T gene.
Garcia-Pavia P, Syrris P, Segovia J, Salas C, Gonzalez-Mirelis J, Gomez-Bueno M, Bornstein B, McKenna WJ, Alonso-Pulpon L, Elliott PM (2010). Mutations in desmosomal genes in heart transplant patients with idiopathic dilated cardiomyopathy.
Kaski JP, Syrris PM, Shaw AC, Esteban MTT, Mckenna WJ, Elliott PM (2010). Mutations in the RAS/MAPK signalling pathway cause idiopathic hypertrophic cardiomyopathy in pre-adolescent children.
Kaski JP, Esteban MTT, Consuegra L, Deanfield JE, McKenna WJ, Elliott PM (2010). Natural history, survival and risk stratification in pre-adolescent hypertrophic cardiomyopathy.
O'mahony C, Elliott P, Syrris P, Evans A, Soresen C, Sheppard M, Pantazis A, Mckenna W (2010). Prevalence of desmosomal protein gene mutations in patients with dilated cardiomyopathy.
Gehmlich K, Asimaki A, Cahill TJ, Ehler E, Syrris P, Zachara E, Re F, Avella A, Monserrat L, Saffitz JE, McKenna WJ (2010). Novel missense mutations in exon 15 of desmoglein-2: role of the intracellular cadherin segment in arrhythmogenic right ventricular cardiomyopathy?. Heart Rhythm, 7(10), 1446 - 1453. doi:10.1016/j.hrthm.2010.08.007
Elliott P, O'Mahony C, Syrris P, Evans A, Rivera Sorensen C, Sheppard MN, Carr-White G, Pantazis A, McKenna WJ (2010). Prevalence of desmosomal protein gene mutations in patients with dilated cardiomyopathy.. Circ Cardiovasc Genet, 3(4), 314 - 322. doi:10.1161/CIRCGENETICS.110.937805
Sen-Chowdhry S, Syrris P, Pantazis A, Quarta G, McKenna WJ, Chambers JC (2010). Mutational heterogeneity, modifier genes, and environmental influences contribute to phenotypic diversity of arrhythmogenic cardiomyopathy.. Circ Cardiovasc Genet, 3(4), 323 - 330. doi:10.1161/CIRCGENETICS.109.935262
Abozguia K, Elliott P, McKenna W, Phan TT, Nallur-Shivu G, Ahmed I, Maher AR, Ashrafian H, Watkins H, Frenneaux MP (2010). METABOLIC ALTERATION IN HYPERTROPHIC CARDIOMYOPATHY (METAL-HCM STUDY): RANDOMISED DOUBLE BLINDED PLACEBO CONTROLLED TRIAL OF PERHEXILINE THERAPY IN PATIENT WITH HYPERTROPHIC CARDIOMYOPATHY. doi:10.1136/hrt.2010.195966.9
Puntmann VO, Yap YG, McKenna W, Camm J (2010). T-Wave Alternans and Left Ventricular Wall Thickness in Predicting Arrhythmic Risk in Patients With Hypertrophic Cardiomyopathy. CIRC J, 74(6), 1197 - 1204. doi:10.1253/circj.CJ-09-1003
Quarta G, Ward D, Tomé Esteban MT, Pantazis A, Elliott PM, Volpe M, Autore C, McKenna WJ (2010). Dynamic electrocardiographic changes in patients with arrhythmogenic right ventricular cardiomyopathy.. Heart, 96(7), 516 - 522. doi:10.1136/hrt.2009.182949
Lambiase PD, Ahmed AK, Ben-Simon R, Chow AW, Lowe MD, McKenna WJ, Ciaccio EJ, Brugada R, Lizotte E, Chaubey (2010). Response to Letter Regarding Article, "High-Density Substrate Mapping in Brugada Syndrome: Combined Role of Conduction and Repolarization Heterogeneities in Arrhythmogenesis". CIRCULATION, 121(11), E249 - E249. doi:10.1161/CIR.0b013e3181d8d4b5
Puntmann VO, Yap YG, McKenna W, Camm AJ (2010). Significance of Maximal and Regional Left Ventricular Wall Thickness in Association With Arrhythmic Events in Patients With Hypertrophic Cardiomyopathy. CIRC J, 74(3), 531 - 537. doi:10.1253/circj.CJ-09-0723
Chambers JC, Zhao J, Terracciano CM, Bezzina CR, Zhang W, Kaba R, Navaratnarajah M, Lotlikar A, Sehmi JS, Kooner MK, Deng G, Siedlecka U, Parasramka S, El-Hamamsy I, Wass MN, Dekker LR, de Jong JS, Sternberg MJ, McKenna W, Severs NJ, de Silva R, Wilde AA, Anand P, Yacoub M, Scott J, Elliott P, Wood JN, Kooner JS (2010). Genetic variation in SCN10A influences cardiac conduction.. Nat Genet, 42(2), 149 - 152. doi:10.1038/ng.516
Sen-Chowdhry S, Morgan RD, Chambers JC, McKenna WJ (2010). Arrhythmogenic Cardiomyopathy: Etiology, Diagnosis, and Treatment. ANNU REV MED, 61, 233 - 253. doi:10.1146/annurev.med.052208.130419
Lambiase PD, Ahmed AK, Ciaccio EJ, Brugada R, Lizotte E, Chaubey S, Ben-Simon R, Chow AW, Lowe MD, McKenna WJ (2010). High-density substrate mapping in Brugada syndrome: combined role of conduction and repolarization heterogeneities in arrhythmogenesis.Letter response,. Circulation, 121, e249 - .
Sen-Chowdhry S, McKenna WJ (2010). Reconciling the protean manifestations of arrhythmogenic cardiomyopathy.. Circ Arrhythm Electrophysiol, 3(6), 566 - 570. doi:10.1161/CIRCEP.110.960237

2009

Elliott P, McKenna W (2009). The science of uncertainty and the art of probability: syncope and its consequences in hypertrophic cardiomyopathy.. Circulation, 119(13), 1697 - 1699.
Kaski J, Syrris P, Tome EM, Jenkins S, Pantazis A, Deanfield J, McKenna W, Elliott P (2009). Prevalence of Sarcomere Protein Gene Mutations in Pre-Adolescent Children with Hypertrophic Cardiomyopathy. Circulation: cardiovascular genetics, 2, 436 - 441.
Messer AE, Gallon CE, McKenna WJ, Dos Remedios CG, Marston SB (2009). The use of phosphate-affinity SDS-PAGE to measure the cardiac troponin I phosphorylation site distribution in human heart muscle. PROTEOM CLIN APPL, 3(12), 1371 - 1382. doi:10.1002/prca.200900071
Taylor J, McKenna WJ (2009). Pioneer in Cardiology: William John McKenna, BA, MD, DSc, FRCP, FMedSci, FESC, FACC. CIRCULATION, 120(19), F109 - F111.
Abozguia K, Elliott P, McKenna W, Phan T, Nallur-Shivu G, Ahmed I, Maher AR, Henning A, Ashrafian H, Watkins H, Frenneaux M (2009). Metabolic Modulation With Perhexiline Corrects Energy Deficiency and Improves Exercise Capacity in Symptomatic Hypertrophic Cardiomyopathy.
McKenna WJ, Kaski JP (2009). Pacemaker Therapy in Hypertrophic Obstructive Cardiomyopathy: Still Awaiting the Evidence. REV ESP CARDIOL, 62(11), 1217 - 1220.
McKenna WJ (2009). Clinical and Molecular Genetics of ARVC.
Seebohm B, Matinmehr F, Kohler J, Francino A, Navarro-Lopez F, Perrot A, Ozcelik C, McKenna WJ, Brenner B, Kraft T (2009). Cardiomyopathy Mutations Reveal Variable Region of Myosin Converter as Major Element of Cross-Bridge Compliance. BIOPHYS J, 97(3), 806 - 824. doi:10.1016/j.bpj.2009.05.023
Marston S, Copeland O, Jacques A, Livesey K, Tsang V, McKenna WJ, Jalilzadeh S, Carballo S, Redwood C, Watkins H (2009). Evidence From Human Myectomy Samples That MYBPC3 Mutations Cause Hypertrophic Cardiomyopathy Through Haploinsufficiency. CIRC RES, 105(3), 219 - U39. doi:10.1161/CIRCRESAHA.109.202440
Moulik M, Vatta M, Witt SH, Arola AM, Murphy RT, McKenna WJ, Boriek AM, Oka K, Labeit S, Bowles NE, Arimura T, Kimura A, Towbin JA (2009). ANKRD1, the Gene Encoding Cardiac Ankyrin Repeat Protein, Is a Novel Dilated Cardiomyopathy Gene. J AM COLL CARDIOL, 54(4), 325 - 333. doi:10.1016/j.jacc.2009.02.076
Lambiase PD, Ahmed AK, Ciaccio EJ, Brugada R, Lizotte E, Chaubey S, Ben-Simon R, Chow AW, Lowe MD, McKenna WJ (2009). High-density substrate mapping in Brugada Syndrome: combined role of conduction and repolarization heterogeneities in arrhythmogenesis. Circulation, 120(2), 106 - 117. doi:10.1161/CIRCULATIONAHA.108.771401
Abozguia K, Shivu GN, Ahmed I, Phan TT, Karla R, Weaver R, McKenna W, Sanderson J, Elliott PM, Frenneaux MP (2009). VENTRICULAR TWIST AND STRAIN IN HYPERTROPHIC CARDIOMYOPATHY: RELATION TO EXERCISE CAPACITY.
Asimaki A, Syrris P, Ward D, Guereta LG, Saffitz JE, McKenna WJ (2009). Unique epidermolytic bullous dermatosis with associated lethal cardiomyopathy related to novel desmoplakin mutations.. J Cutan Pathol, 36(5), 553 - 559. doi:10.1111/j.1600-0560.2008.01112.x
Sen-Chowdhry S, Syrris P, Prasad SK, Hughes SE, Merrifield R, Ward D, Pennell DJ, McKenna WJ (2009). Left Dominant Arrhythmogenic Cardiomyopathy A New Clinical Entity Without a Typical Substrate of Myocardial Damage Reply. J AM COLL CARDIOL, 53(17), 1571 - 1572. doi:10.1016/j.jacc.2009.01.045
Asimaki A, Tandri H, Huang H, Halushka MK, Gautam S, Basso C, Thiene G, Tsatsopoulou A, Protonotarios N, McKenna WJ, Calkins H, Saffitz JE (2009). A new diagnostic test for arrhythmogenic right ventricular cardiomyopathy. N.Engl.J.Med., 360(11), 1075 - 1084.
Moon JC, McKenna WJ (2009). The emerging role of cardiovascular magnetic resonance in refining the diagnosis of hypertrophic cardiomyopathy.. Nat Clin Pract Cardiovasc Med, 6(3), 166 - 167. doi:10.1038/ncpcardio1442
Elliott P, McKenna WJ (2009). How should hypertrophic cardiomyopathy be classified?: Molecular diagnosis for hypertrophic cardiomyopathy: Not ready for prime time.. Circ Cardiovasc Genet, 2(1), 87 - 89. doi:10.1161/CIRCGENETICS.108.835645
Simpson MA, Mansour S, Ahnood D, Kalidas K, Patton MA, McKenna WJ, Behr ER, Crosby AH (2009). Homozygous Mutation of Desmocollin-2 in Arrhythmogenic Right Ventricular Cardiomyopathy with Mild Palmoplantar Keratoderma and Woolly Hair. CARDIOLOGY, 113(1), 28 - 34. doi:10.1159/000165696
Coats CJ, Quarta G, Flett AS, Pantazis AA, McKenna WJ, Moon JC (2009). Arrhythmogenic left ventricular cardiomyopathy.. Circulation, 120(25), 2613 - 2614. doi:10.1161/CIRCULATIONAHA.109.874628

2008

McKenna WJ (2008). Diseases of the myocardium and endocardium. In Goldman L, Ausiello D (Ed.), Cecil Medicine 23rd edition (pp. 372 - 390). : Saunders Elsevier.
Sen-Chowdhry S, McKenna WJ (2008). The utility of magnetic resonance imaging in the evaluation of arrhythmogenic right ventricular cardiomyopathy.. Curr Opin Cardiol, 23(1), 38 - 45. doi:10.1097/HCO.0b013e3282f2c96e
Menasché P, Alfieri O O, Janssens S, McKenna WJ, Reichenspurner H, Trinquart L, Vilquin J-T, Marolleau J-P, Seymour B, Larghero J, Lake S, Chatellier G, Solomon S, Desnos M, Hagège AA (2008). The Myoblast Autologous Grafting in Ischemic Cardiomyopathy (MAGIC) Trial. First Randomized Placebo-Controlled Study of Myoblast Transplantation. Circulation, 117(9), 1189 - 1200.
Huang H, Asimaki A, Lo D, McKenna W, Saffitz J (2008). Disparate Effects of Different Mutations in Plakoglobin on Cell Mechanical Behavior. CELL MOTIL CYTOSKEL, 65(12), 964 - 978. doi:10.1002/cm.20319
McKenna WJ, Sen-Chowdhry S (2008). From Teare to the Present Day: A Fifty Year Odyssey in Hypertrophic Cardiomyopathy, a Paradigm for the Logic of the Discovery Process. REV ESP CARDIOL, 61(12), 1239 - 1244.
Kaski JP, Syrris P, Burch M, Tomé-Esteban MT, Fenton M, Christiansen M, Andersen PS, Sebire N, Ashworth M, Deanfield JE, McKenna WJ, Elliott PM (2008). Idiopathic restrictive cardiomyopathy in children is caused by mutations in cardiac sarcomere protein genes.. Heart, 94(11), 1478 - 1484. doi:10.1136/hrt.2007.134684
Sen-Chowdhry S, Sevdalis E, Wage R, Mist B, Kilner PJ, McKenna WJ (2008). Syncope in an adolescent: a case of conflicting tests and dual pathology.. Int J Clin Pract, 62(11), 1803 - 1807. doi:10.1111/j.1742-1241.2006.00898.x
Caforio AL, Zachara E, Vinci A, Re F, Baratta P, Tona F, Thiene G, Iliceto S, Tondo C, McKenna WJ (2008). Serum Organ-Specific Anti-Heart Autoantibodies in Arrhythmogenic Right Ventricular Cardiomyopathy Patients and Relatives: Evidence for Autoimmune Involvement in a Genetically-Determined Myocarditis.
Kaski JP, Tome-Esteban MT, Mead-Regan SJ, Pantazis A, Marek J, Deanfield JE, McKenna WJ, Elliott PMM (2008). B-type natriuretic peptide predicts disease severity in children with hypertrophic cardiomyopathy. Heart, 94(10), 1307 - 1311.
Elliott P, McKenna W (2008). Hypertrophic cardiomyopathy: a 50th anniversary. Preface.. Heart, 94(10), 1247 - 1248. doi:10.1136/hrt.2008.154344
Frank-Hansen R, Page SP, Syrris P, McKenna WJ, Christiansen M, Andersen PS (2008). Micro-exons of the cardiac myosin binding protein C gene: flanking introns contain a disproportionately large number of hypertrophic cardiomyopathy mutations.. Eur J Hum Genet, 16(9), 1062 - 1069. doi:10.1038/ejhg.2008.52
Jacques AM, Copeland O, Messer AE, Gallon CE, King K, McKenna WJ, Tsang VT, Marston SB (2008). Myosin binding protein C phosphorylation in normal, hypertrophic and failing human heart muscle. J MOL CELL CARDIOL, 45(2), 209 - 216. doi:10.1016/j.yjmcc.2008.05.020
Carballo S, Copeland O, Livesey K, Jacques A, McKenna W, Redwood C, Marston S, Watkins H (2008). Direct evidence in man for haploinsufficiency as the mechanism of action of myosin-binding protein C mutations that cause hypertrophic cardiomyopathy.
Sen-Chowdhry S, McKenna WJ (2008). Non-invasive risk stratification in hypertrophic cardiomyopathy: don't throw out the baby with the bathwater. EUR HEART J, 29(13), 1600 - 1602. doi:10.1093/eurheartj/ehn238
Rogers DP, Marazia S, Chow AW, Lambiase PD, Lowe MD, Frenneaux M, McKenna WJ, Elliott PM (2008). Effect of biventricular pacing on symptoms and cardiac remodelling in patients with end-stage hypertrophic cardiomyopathy.. Eur J Heart Fail, 10(5), 507 - 513. doi:10.1016/j.ejheart.2008.03.006
Sen-Chowdhry S, McKenna WJ (2008). Left ventricular noncompaction and cardiomyopathy: cause, contributor, or epiphenomenon?. Curr Opin Cardiol, 23(3), 171 - 175. doi:10.1097/HCO.0b013e3282fdc939
Keren A, Syrris P, McKenna WJ (2008). Hypertrophic cardiomyopathy: the genetic determinants of clinical disease expression.. Nat Clin Pract Cardiovasc Med, 5(3), 158 - 168. doi:10.1038/ncpcardio1110
Kohli SK, Pantazis AA, Shah JS, Adeyemi B, Jackson G, McKenna WJ, Sharma S, Elliott PM (2008). Diagnosis of left-ventricular non-compaction in patients with left-ventricular systolic dysfunction: time for a reappraisal of diagnostic criteria?. European Heart Journal, 29(1), 89 - 95.
Rogers DP, Marazia S, Chow AW, Lambiase PD, Lowe MD, Frenneaux M, McKenna WJ, Elliott PM (2008). Effect of biventricular pacing on symptoms and cardiac remodelling in patients with end-stage hypertrophic cardiomyopathy.. 2008 May;10(5):507-13. Epub 2008 Apr 10.. European Journal of Heart Failure, 10(5), 507 - 513.
Garratt CJ, Elliott P, Behr E, Blair E, Connelly D, Cowan C, Davidson N, Grace A, Griffith M, Jolly A, Lambiase P, McKenna W (2008). Heart Rhythm UK Familial Sudden Death Syndromes Statement Development Group. Clinical indications for genetic testing in familial sudden cardiac death syndromes: an HRUK position statement.. Heart, 94(4), 502 - 507.
Kaski JP, Syrris P, Burch M, Tome-Esteban MTT, Fenton M, Christiansen M, Andersen PS, Sebire NJ, Ashworth M, Deanfield JE, McKenna WJ, Elliott PM (2008). Idiopathic Restrictive Cardiomyopathy in Children is Caused by Mutations in Cardiac Sarcomere Protein Genes.
Shah JS, Esteban MT, Thaman R, Sharma R, Mist B, Pantazis A, Ward D, Kohli SK, Page SP, Demetrescu C, Sevdalis E, Keren A, Pellerin D, McKenna WJ, Elliott PM (2008). Prevalence of exercise-induced left ventricular outflow tract obstruction in symptomatic patients with non-obstructive hypertrophic cardiomyopathy.. Heart, 94(10), 1288 - 1294.
Morgan JF, O'Donoghue AC, McKenna WJ, Schmidt MM (2008). Psychiatric disorders in hypertrophic cardiomyopathy. GEN HOSP PSYCHIAT, 30(1), 49 - 54. doi:10.1016/j.genhosppsych.2007.09.005
Sen-Chowdhry S, Syrris P, Prasad SK, Hughes SE, Merrifield R, Ward D, Pennell DJ, McKenna WJ (2008). Left-dominant arrhythmogenic cardiomyopathy: an under-recognized clinical entity.. J Am Coll Cardiol, 52(25), 2175 - 2187. doi:10.1016/j.jacc.2008.09.019

2007

Sen-Chowdhry S, Syrris P, McKenna WJ (2007). Role of genetic analysis in the management of patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy.. J Am Coll Cardiol, 50(19), 1813 - 1821. doi:10.1016/j.jacc.2007.08.008
Caforio AL, Mahon NG, Baig MK, Tona F, Murphy RT, Elliott PM, McKenna WJ (2007). Prospective familial assessment in dilated cardiomyopathy: cardiac autoantibodies predict disease development in asymptomatic relatives.. Circulation, 115(1), 76 - 83.
Asimaki A, Huang H, McKenna WJ, Saffitz JE (2007). Disparate biomechanical effects of two arrhythimogenic right ventricular cardiomyopathy-causing mutations in plakoglobin.
Melacini P, Cianfrocca C, Calore C, Bovolato F, Di Paolo F, Quattrini F, Pelliccia F, Sharma S, McKenna WJ, Maron BJ, Pelliccia A, Corrado D (2007). Marginal overlap between electrocardiographic abnormalities in patients with hypertrophic cardiomyopathy and trained athletes: Implications for preparticipation screening.
Corrado D, Leoni L, Link MS, Calkins H, Wichter T, Bevilacqua M, Basso C, McKenna WJ, Estes MN, Favale S, Santini M, Buja G, Thiene G, Iliceto S (2007). Programmed ventricular stimulation does not predict the outcome of patients with arrhythmogenic right ventricular cardiomyopathy (from DARVIN study).
Lambiase PD, Kaski JC, Firman E, Elliott PM, Ahmed AK, Chow AW, Sheppard M, Lowe MD, Christiansen M, McKenna WJ (2007). Sudden arrhythmic death syndrome-diagnostic yield of combined clinical & genetic screening in a British specialist clinic.
Limongelli G, Pacileo G, Marino B, Digilio MC, Sarkozy A, Elliott P, Versacci P, Calabro P, De Zorzi A, Di Salvo G, Syrris P, Patton M, McKenna WJ, Dallapiccola B, Calabro R (2007). Prevalence and clinical significance of cardiovascular abnormalities in patients with the LEOPARD syndrome.. Am J Cardiol, 100(4), 736 - 741. doi:10.1016/j.amjcard.2007.03.093
Corrado D, McKenna WJ (2007). Appropriate interpretation of the athlete's electrocardiogram saves lives as well as money. EUR HEART J, 28(16), 1920 - 1922. doi:10.1093/eurheartj/ehm275
Holmqvist F, Platonov PG, Carlson J, Havmoller R, Waktare JEP, McKenna WJ, Olsson SB, Meurling CJ (2007). Variable interatrial conduction illustrated in a hypertrophic cardiomyopathy population. ANN NONINVAS ELECTRO, 12(3), 227 - 236.
Lambiase P, Kaski J, Firman E, Elliott P, Ahmed A, Chow A, Hughes S, Sheppard M, Lowe M, McKenna W (2007). Sudden arrhythmic death syndrome: Diagnostic yield of clinical screening in family members at the Heart Hospital, University College London, 2003-6.
Sen-Chowdhry S, Syrris P, Ward D, Asimaki A, Sevdalis E, McKenna WJ (2007). Clinical and genetic characterization of families with arrhythmogenic right ventricular dysplasia/cardiomyopathy provides novel insights into patterns of disease expression.. Circulation, 115(13), 1710 - 1720. doi:10.1161/CIRCULATIONAHA.106.660241
Syrris P, Ward D, Asimaki A, Evans A, Sen-Chowdhry S, Hughes SE, McKenna WJ (2007). Desmoglein-2 mutations in arrhythmogenic right ventricular cardiomyopathy: a genotype-phenotype characterization of familial disease. EUR HEART J, 28(5), 581 - 588. doi:10.1093/eurheartj/hl380
Syrris P, Ward D, Asimaki A, Evans A, Sen-Chowdhry S, Hughes SE, McKenna WJ (2007). Desmoglein-2 mutations in arrhythmogenic right ventricular cardiomyopathy: a genotype-phenotype characterization of familial disease.. European Heart Journal, 28(5), 581 - 588.
Caforio AL, Mahon NG, Baig MK, Tona F, Murphy RT, Elliott PM, McKenna WJ (2007). Prospective familial assessment in dilated cardiomyopathy: cardiac autoantibodies predict disease development in asymptomatic relatives.. Circulation, 115(1), 76 - 83. doi:10.1161/CIRCULATIONAHA.106.641472
Arola AM, Sanchez X, Murphy RT, Hasle E, Li H, Elliott PM, McKenna WJ, Towbin JA, Bowles NE (2007). Mutations in PDLIM3 and MYOZ1 encoding myocyte Z line proteins are infrequently found in idiopathic dilated cardiomyopathy.. Molecular Genetics and Metabolism, 90(4), 435 - 440.
Kaski JP, Tomé Esteban MT, Lowe M, Sporton S, Rees P, Deanfield JE, McKenna WJ, Elliott PM (2007). Outcomes Following Implantable Cardioverter-Defibrillator Therapy in Children with Hypertrophic Cardiomyopathy. Heart, , - .
Kubo T, Gimeno JR, Bahl A, Steffensen U, Steffensen M, Osman E, Thaman R, Mogensen J, Elliott PM, Doi Y, McKenna WJ (2007). Prevalence, clinical significance, and genetic basis of hypertrophic cardiomyopathy with restrictive phenotype.. Journal of the American College of Cardiology, 49(25), 2419 - 2426.
Asimaki A, Syrris P, Wichter T, Matthias P, Saffitz JE, McKenna WJ (2007). A novel dominant mutation in plakoglobin causes arrhythmogenic right ventricular cardiomyopathy.. Am J Hum Genet, 81(5), 964 - 973. doi:10.1086/521633

2006

Sen-Chowdhry S, McKenna WJ (2006). Sudden cardiac death in the young: the impact of inherited cardiovascular disease. In Topol EJ, Califf RM, Prystowsky EN, Thomas JD, Thompson PD (Ed.), Textbook of Cardiovascular Medicine (pp. - ). : Lippincott-Raven Publishers.
Thaman R, Esteban MT, Barnes S, Gimeno JR, Mist B, Murphy R, Collinson PO, McKenna WJ, Elliott PM (2006). Usefulness of N-terminal pro-B-type natriuretic Peptide levels to predict exercise capacity in hypertrophic cardiomyopathy.. The American Journal of Cardiology, 98(4), 515 - 519.
Caforio AL, Zachara E, Re F, Bottaro S, Baratta P, Tona F, Vinci A, Dequal G, Gerosa G, Thiene G, McKenna WJ, Iliceto S, Toldo C (2006). High frequency of circulating organ-specific anti-heart autoantibodies in arrhythmogenic right ventricular cardiomyopathy: Evidence of immune-mediated pathogenesis.
Stoevring B, Andersen PS, Havndrup O, Bundgaard H, Mckenna WJ, Christiansen M (2006). Novel mutations in the molecular chaperone alphaB-Crystallin cause cardiomyopathies.
Corrado D, Leoni L, Calkins H, Favale S, Ward D, Boriani G, Link MS, Ricci S, Piccini JP, Basso C, Dalal D, Estes NAM, Santini M, Buja G, McKenna WJ, Thiene G, Iliceto S (2006). Prophylactic implantable defibrillator in patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia and no prior sustained ventricular tachyarrhythmias: Therapy-based risk stratification during a long term follow-up.
Antoniades L, Tsatsopoulou A, Anastasakis A, Syrris P, Asimaki A, Panagiotakos D, Zambartas C, Stefanadis C, McKenna WJ, Protonotarios N (2006). Arrhythmogenic right ventricular cardiomyopathy caused by deletions in plakophilin-2 and plakoglobin (Naxos disease) in families from Greece and Cyprus: genotype-phenotype relations, diagnostic features and prognosis.. European Heart Journal, 27(18), 2208 - 2016.
Kaski JP, Tome Esteban MT, Lowe MD, Sporton S, Rees P, Deanfield JE, McKenna WJ, Elliott PM (2006). Outcomes Following Implantable Cardioverter-Defibrillator Therapy in Children with Hypertrophic Cardiomyopathy. Heart, , - .
Pantazis AA, Kohli SK, Sharma S, Jackson G, Shah J, Mckenna WJ, Elliott PM (2006). A comparison of published diagnostic criteria for left ventricular noncompaction in patients with heart failure.
Dhillon PS, Patel PM, Gray R, Jacques A, Marston S, Mckenna W, Fry CH, Peters NS (2006). Increased connexin 43 expression in the left ventricular septum is associated with a family history of sudden cardiac death in patients with hypertrophic obstructive cardiomyopathy.
Dhillon PS, Patel PM, Gray R, Jacques A, Marston S, Fry CH, Mckenna W, Peters NS (2006). Intracellular and gap-junction conductance correlates with connexin43 quantity in left ventricular septal myocardium in patients with hypertrophic obstructive cardiomyopathy.
Christiansen M, Stoevring B, Havndrup O, Bundgaard H, Andersen PS, Mckenna WJ (2006). Mutations in CRYAB cause hypertrophic cardiomyopathy.
Frank-Hansen R, Andersen PS, Havndrup O, Bundgaard H, Mckenna WJ, Christiansen M (2006). The significance of polymorphisms and intronic variants in MYBPC3: Pitfalls in genetic diagnosis of hypertrophic cardiomyopathy.
Dhillon P, Patel P, Gray R, Jacques A, Marston S, Tsang V, Fry C, McKenna W, Peters N (2006). Increased connexin43 expression in the left ventricular septum is associated with a family history of sudden cardiac death in patients with hypertrophic obstructive cardiomyopathy.
Dhillon P, Patel P, Gray R, Jacques A, Chowdhury R, Martins YA, Tsang V, Marston S, Fry C, McKenna W, Peters N (2006). Intracellular and gap-junction conductance correlates with connexin43 quantity in left ventricular septal myocardium in patients with hypertrophic obstructive cardiomyopathy.
Sen-Chowdhry S, Syrris P, McKenna WJ, Norman M, Mogensen J, Shaw A, Rowland E, Simpson M, Crosby A, Hughes S (2006). Letter regarding article by Norman et al, "Novel mutation in desmoplakin causes arrhythmogenic left ventricular cardiomyopathy" - Response. CIRCULATION, 113(5), E69 - E69. doi:10.1161/CIRCULATIONAHA.105.581868
Syrris P, Ward D, Asimaki A, Sen-Chowdhry S, Ebrahim HY, Evans A, Hitomi N, Norman M, Pantazis A, Shaw AL, Elliott PM, McKenna WJ (2006). Clinical expression of plakophilin-2 mutations in familial arrhythmogenic right ventricular cardiomyopathy. Circulation, 113(3), 356 - 364. doi:10.1161/CIRCULATIONAHA.105.561654
Tsatsopoulou AA, Protonotarios NI, McKenna WJ (2006). Arrhythmogenic right ventricular dysplasia, a cell-adhesion cardiomyopathy: insights into disease pathogenesis from preliminary genotype-phenotype assessment. Heart, , - .
Syrris P, Ward D, Evans A, Asimaki A, Gandjbakhch E, Sen-Chowdhry S, McKenna WJ (2006). Arrhythmogenic right ventricular dysplasia/cardiomyopathy associated with mutations in the desmosomal gene desmocollin-2.. The American Journal of Human Genetics, 79, 978 - 984. doi:10.1086/509122
Caforio A, Mahon N, Tona F, McKenna W (2006). Circulating cardiac autoantibodies in dilated cardiomyopathy and myocarditis: pathogenetic and clinical significance. European Journal of Heart Failure, 4(4), 411 - .
Varma C, O'Callaghan P, Rowland E, Mahon NG, McKenna W, Camm AJ, Brecker SJ (2006). Comparison between biventricular pacing and single site pacing in patients with poor ventricular function: a hemodynamic study.. PACE, 26(2), 551 - 558.
Elliott PM, Kindler H, Shah JS, Sachdev B, Rimoldi O, Tomé MT, McKenna WJ, Lee P, Camici PG (2006). Coronary Microvascular Dysfunction in Male Patients With Anderson-Fabry Disease and the Effect of Treatment With Alpha Galactosidase A.. Heart, 92(3), 357 - 360.
Mercuri E, Brown SC, Nihoyannopoulos P, Poulton J, Kinali M, Richard P, Piercy R, Messina S, Sewry C, Burke MM, McKenna W, Bonne G, Muntoni F (2006). Extreme variability of skeletal and cardiac muscle involvement in patients with mutations in exon 11 of the lamin A/C gene. Muscle & Nerve, 31(5), 602 - 609.
Hofman-Bang J, Behr ER, Hedley P, Tfelt-Hansen J, Kanters JK, Haunsø S, McKenna WJ, Christiansen M (2006). High-efficiency Multiplex Capillary Electrophoresis Single Strand Conformation Polymorphism (Multi-CE-SSCP) Mutation Screening of SCN5A: A Rapid Genetic Approach to Cardiac Arrhythmia.. Clinical Genetics, 69(6), 504 - 511.
Elliott PM, Gimeno JR, Thaman R, Shah J, Ward D, Dickie S, Tomé MT, McKenna WJ (2006). Historical Trends in Reported Survival Rates in Patients with Hypertrophic Cardiomyopathy. Heart, 92, 785 - 791.
Elliott PM, Gimeno JR, Thaman R, Shah J, Ward D, Dickie S, Tomé MT, McKenna WJ (2006). Historical trends in reported survival rates in patients with hypertrophic cardiomyopathy. Heart, 92(3), 357 - 360.
McKoy G, Protonotarios N, Crosby A, Tsatsopoulou A, Anastasakis A, Coonar A, Toutouzas P, Norman M, Baboonian C, Jeffery S, McKenna WJ (2006). Identification of a deletion in plakoglobin in arrhythmogenic right ventricular cardiomyopathy with palmoplantar keratoderma and woolly hair (Naxos disease). The Lancet, 355, 2119 - 2124.
Elliott PM, Gimeno JR, Tomé MT, Shah J, Ward D, Thaman R, Mogensen J, McKenna WJ (2006). Left Ventricular Outflow Tract Obstruction and Sudden Death Risk in Patients with Hypertrophic Cardiomyopathy.. European Heart Journal, 27(16), 1933 - 1941.
Sharma R, Smith J, Elliott PM, McKenna WJ, Pellerin D (2006). Left ventricular outflow tract obstruction caused by accessory mitral valve tissue. Journal of the American Society of Echocardiography, 19(3), 354.E5 - 354.E8.
Whyte G, Lumley S, George K, Gates P, Sharma S, Prasad K, McKenna WJ (2006). Physiological profile and predictors of cycling performance in ultra-endurance triathletes. Journal of Sports Medicine and Physical Fitness, 40(2), 103 - 109.
Sen-Chowdhry S, McKenna WJ (2006). Sudden cardiac death in the young: a strategy for prevention by targeted evaluation.. Cardiology, 105(4), 196 - 206. doi:10.1159/000091640
Levine TBFTM-1I (2006). The design of the mortality assessment in congestive heart failure trial (MACH-1, Mibefradil).. Clinical Cardiology, 20(320), 326 - .
Sen-Chowdhry S, Prasad SK, Syrris P, Wage R, Ward D, Merrifield R, Smith GC, Firmin DN, Pennell DJ, McKenna WJ (2006). Cardiovascular magnetic resonance in arrhythmogenic right ventricular cardiomyopathy revisited: comparison with task force criteria and genotype.. J Am Coll Cardiol, 48(10), 2132 - 2140. doi:10.1016/j.jacc.2006.07.045

2005

Norman M, Simpson M, Jens M, Shaw A, Hughes S, Sen-Chowdry S, Rowland E, Crosby A, McKenna WJ (2005). A novel desmoplakin mutation causes left ventricular arrhythmogenic ventricular cardiomyopathy.
Sharma S, McKenna WJ (2005). The role of electrophysiological studies in the evaluation and management of hypertrophic cardiomyopathy.. Cardiac Electrophysiology Review, , - .
Gray R, Dhillon P, Jacques A, Peters N, Walker M, McIntyre H, McKenna W, Fry C (2005). Electromechanical properties of isolated myocardium from patients with hypertrophic obstructive cardiomyopathy (hocm).
Thaman R, Elliott PM, Shah JS, Mist B, Williams L, Murphy RT, McKenna WJ, Frenneaux MP (2005). Reversal of inappropriate peripheral vascular responses in hypertrophic cardiomyopathy.. J Am Coll Cardiol, 46(5), 883 - 892. doi:10.1016/j.jacc.2005.05.053
Pelliccia A, Fagard R, Bjornstad HH, Anastassakis A, Arbustini E, Assanelli D, Biffi A, Borjesson M, Carre F, Corrado D, Delise P, Dorwarth U, Hirth A, Heidbuchel H, Hoffmann E, Mellwig KP, Panhuyzen-Goedkoop N, Pisani A, Solberg EE, Van-Buuren F, Vanhees L, Blomstrom-Lundqvist C, Deligiannis A, Dugmore D, Glikson M, Hoff PI, Hoffmann A, Horstkotte D, Nordrehaug JE, Oudhof J, Mckenna WJ, Penco M, Prior S, Reybrouck T, Senden PJF, Spataro A, Thiene G, Study Grp Sports Cardiology Workin , Working Grp Myocardial Pericardial (2005). Recommendations for competitive sports participation in athletes with cardiovascular disease. MED SPORT, 58(3), 157 - 191.
Norman M, Simpson M, Mogensen J, Shaw A, Hughes S, Syrris P, Sen-Chowdhry S, Rowland E, Crosby A, McKenna WJ (2005). Novel mutation in desmoplakin causes arrhythmogenic left ventricular cardiomyopathy.. Circulation, 112(5), 636 - 642. doi:10.1161/CIRCULATIONAHA.104.532234
Sen-Chowdhry S, Syrris P, McKenna WJ (2005). Desmoplakin disease in arrhythmogenic right ventricular cardiomyopathy: early genotype-phenotype studies.. Eur Heart J, 26(16), 1582 - 1584. doi:10.1093/eurheartj/ehi343
Murphy RT, Mogensen J, McGarry K, Bahl A, Evans A, Osman E, Syrris P, Gorman G, Farrell M, Holton JL, Hanna MG, Hughes S, Elliott PM, Macrae CA, McKenna WJ (2005). Adenosine monophosphate-activated protein kinase disease mimicks hypertrophic cardiomyopathy and Wolff-Parkinson-White syndrome: natural history. Journal of the American College of Cardiology, 45(6), 922 - 930.
Kirschner SE, Becker E, Antognozzi M, Kubis HP, Francino A, Navarro-Lopez F, Bit-Avragim N, Perrot A, Mirrakhimov MM, Osterziel KJ, McKenna WJ, Brenner B, Kraft T (2005). Hypertrophic cardiomyopathy-related beta-myosin mutations cause highly variable calcium sensitivity with functional imbalances among individual muscle cells.. American Journal of Physiology - Heart and Circulatory Physiology, 288(3), H1242 - H1251.
Norman MW, Simpson M, Mogensen J, Shaw A, Hughes S, Sen-Chowdhry S, Rowland E, Crosby A, McKenna WJ (2005). A novel mutation in desmoplakin causes arrhythmogenic left ventricular cardiomyopathy. Circulation, 112(5), 636 - 642.
Caforio ALP, Daliento L, Angelini A, Bottaro S, Vinci A, Dequal G, Tona F, Iliceto S, Thiene G, McKenna WJ (2005). Autoimmune myocarditis and dilated cardiomyopathy: focus on cardiac autoantibodies.. Lupus, 14(9), 652 - 655.
Corrado D, Pelliccia A, Bjornstad HH, Vanhees L, Biffi A, Borjesson M, Panhuyzen-Goedkoop D, A S, E D, D M, K P A, D D, P V-B, F A, A H, H H, E F, R P, S G B, C A, E B-L, C M, W J T, G (2005). Cardiovascular pre-participation screening of young competitive athletes for prevention of sudden death: proposal for a common European protocol. Consensus Statement of the Study Group of Sport Cardiology of the Working Group of Cardiac Rehabilitation and Exercise Physiology and the Working Group of Myocardial and Pericardial Diseases of the European Society of Cardiology.. European Heart Journal, 26(5), 516 - 524.
Sen-Chowdhry S, Syrris P, McKenna WJ (2005). Desmoplakin disease in arrhythmogenic right ventricular cardiomyopathy: early genotype–phenotype studies [editorial].. European Heart Journal, 26(16), 1582 - 1584.
Mirza M, Marston S, Willott R, Ashley C, Mogensen J, McKenna W, Robinson P, Redwood C, Watkins H (2005). Dilated cardiomyopathy mutations in three thin filament regulatory proteins result in a common functional phenotype.. Journal of Biological Chemistry, 280(31), 28498 - 28506.
Mahon NG, Murphy RT, MacRae CA, Caforio AL, Elliott PM, McKenna WJ (2005). Echocardiographic evaluation in asymptomatic relatives of patients with dilated cardiomyopathy reveals preclinical disease.. Annals of Internal Medicine, 143(2), 108 - 115.
Robinson PJ, Mirza M, Marston S, Willott R, Ashley C, Mogensen J, McKenna W, Watkins H, Redwood C (2005). Effects of DCM mutations in thin filament regulatory proteins on contractile function.
Grunnet M, Behr ER, Calloe K, Hoffman-Bang J, Till J, Christiansen M, McKenna WJ, Olesen SP, Schmitt N (2005). Functional assessment of compound mutations in the KCNQ1 and KCNH2 genes associated with long QT syndrome. Heart Rhythm, 2, 1238 - 1249.
Sen-Chowdhry S, Syrris P, McKenna WJ (2005). Genetics of right ventricular cardiomyopathy. Journal of Cardiovascular Electrophysiology, 16(8), 927 - 935.
Sherrid MV, Barac I, McKenna WJ, Elliott PM, Dickie S, Chojnowska L, Casey SA, Maron BJ (2005). Multicenter Study of the Efficacy and Safety of Disopyramide in Obstructive Hypertrophic Cardiomyopathy. Journal of the American College of Cardiology, 45(8), 1251 - 1258.
Moon JC, Mogensen J, Elliott PM, Smith GC, Elkington AG, Prasad SK, Pennell DJ, McKenna WJ (2005). Myocardial enhancement by cardiovascular magnetic resonance in hypertrophic cardiomyopathy caused by mutations in troponin I.. Heart, 91(8), 1036 - 1040.
Moon JC, Mogensen J, Elliott PM, Smith GC, Elkington AG, Prasad SK, Pennell DJ, McKenna WJ (2005). Myocardial late gadolinium enhancement cardiovascular magnetic resonance in hypertrophic cardiomyopathy caused by mutations in troponin I. Heart, 91, 1036 - 1040.
Murphy RT, Thaman R, Gimeno Blanes J, Ward D, Sevdalis E, Papra E, Kiotsekolglou A, Tome MT, Pellerin D, McKenna WJ, Elliott PM (2005). Natural History and Familial Characteristics of Isolated Left Ventricular Non-Compaction. European Heart Journal, 26, 187 - 192.
Hughes SE, McKenna WJ (2005). New insights into the pathology of inherited cardiomyopathy. Heart, (91), 257 - 264.
Makan J, Sharma S, Firoozi S, Whyte G, Jackson PG, McKenna WJ (2005). Physiological upper limits of ventricular cavity size in highly trained adolescent athletes. Heart, 91(4), 495 - 499.
Thaman R, Gimeno JR, Murphy RT, Kubo T, Sachdev B, Mogensen J, Elliott PM, McKenna WJ (2005). Prevalence and Clinical Significance of Systolic Impairment in Hypertrophic Cardiomyopathy.. Heart, 91, 920 - 925.
Thaman R, Gimeno JR, Murphy RT, Kubo T, Sachdev B, Mogensen J, Elliott PM, McKenna WJ (2005). Prevalence and Clinical Significance of Systolic Impairment in Hypertrophic Cardiomyopathy.. Heart, 91(7), 920 - 925.
Pelliccia A, Fagard R, Bjornstad HH, Anastasakis A, Arbustini E, Assanelli D, Biffi A, Borjesson M, Carre F, Corrado D, Delise P, Dorwarth U, Hirth A, Heidbuchel H, Hoffmann E, Mellwig KP, Panhuyzen-Goedkoop N, Pisani A, Solberg EE, van-Buuren F, Vanhees L, Blomstrom-Lundqvist C, Deligiannis A, Dugmore D, Glikson H, P I H, A H, E H, D N, J E O, J M, W J P, M P, S R, T S, J S, A T, G (2005). Recommendations for competitive sports participation in athletes with cardiovascular disease.. European Heart Journal, 26(14), 1422 - 1445.
Thaman R, Elliott PM, Shah JS, Mist B, Williams L, Murphy RT, McKenna WJ, Frenneaux MP (2005). Reversal of inappropriate peripheral vascular responses in hypertrophic cardiomyopathy.. Journal of the American College of Cardiology, 46, 883 - 892.
Thaman R, Elliott PM, Shah JS, Mist B, Williams L, Murphy RT, McKenna WJ, Frenneaux MP (2005). Thaman R, Elliott PM, Shah JS, Mist B, Williams L, Murphy RT, McKenna WJ, Frenneaux MP. Reversal of Inappropriate Peripheral Vascular Responses in Hypertrophic Cardiomyopathy.. Journal of the American College of Cardiology, 46(5), 883 - 892.
Hodgkinson KA, Parfrey PS, Bassett AS, Kupprion C, Drenckhahn J, Norman MW, Thierfelder L, Stuckless SN, Dicks EL, McKenna WJ, Connors SP (2005). The impact of implantable cardioverter-defibrillator therapy on survival in autosomal-dominant arrhythmogenic right ventricular cardiomyopathy (ARVD5). Journal of the American College of Cardiology, 45(3), 400 - 408.
Watkins H, McKenna WJ (2005). The prognostic impact of septal myectomy in obstructive hypertrophic cardiomyopathy. Journal of the American College of Cardiology, 46(3), 477 - 479.
Borggrefe M, Veltmann C, McKenna W (2005). Efficacy of implantable cardioverter defibrillators for prevention of sudden cardiac death in young patients with hypertrophic cardiomyopathy.

2004

Mogensen J, Murphy RT, Shaw T, Bahl A, Redwood C, Watkins H, Burke M, Elliott PM, McKenna WJ (2004). Severe disease expression of cardiac troponin C and T mutations in patients with idiopathic dilated cardiomyopathy.. Journal of the American College of Cardiology, 44(10), 2033 - 2040.
Sen-Chowdhry S, Lowe MD, Sporton SC, McKenna WJ (2004). Arrhythmogenic right ventricular cardiomyopathy: clinical presentation, diagnosis, and management.. The American Journal of Medicine, 117(9), 685 - 695.
Sen-Chowdhry S, Lowe MD, Sporton SC, McKenna WJ (2004). Arrhythmogenic right ventricular cardiomyopathy: clinical presentation, diagnosis, and management.. Am J Med, 117(9), 685 - 695. doi:10.1016/j.amjmed.2004.04.028
Behr ER, Syrris P, Dalageorgou C, Christiansen M, Jeffery S, McKenna WJ (2004). Sudden arrhythmic death syndrome: Cardiological evaluation identifies inherited heart disease in over half of all families.
Tome Esteban MT, Garcia-Pinilla JM, McKenna WJ (2004). [Update in arrhythmogenic right ventricular cardiomyopathy: genetic, clinical presentation and risk stratification]. Revista Española de Cardiología, 57(8), 757 - 767.
Sen-Chowdhry S, Prasad SK, McKenna WJ (2004). Complementary role of echocardiography and cardiac magnetic resonance in the non-invasive evaluation of suspected arrhythmogenic right ventricular cardiomyopathy.. Journal of Interventional Cardiac Electrophysiology, 11(1), 15 - 17.
Sen-Chowdhry S, Prasad SK, McKenna WJ (2004). Complementary role of echocardiography and cardiac magnetic resonance in the non-invasive evaluation of suspected arrhythmogenic right ventricular cardiomyopathy.. J Interv Card Electrophysiol, 11(1), 15 - 17. doi:10.1023/B:JICE.0000035923.16175.78
Tsatsopoulou AA, Kaplan SR, Gard JJ, Basso C, Anastasakis A, McKenna WJ, Protonotarios NI, Saffitz JE (2004). Remodeling of gap junctions in Naxos disease: a potential mechanism of lethal arrhythmias in arrhythmogenic right ventricular cardiomyopathy.
Whyte GP, George K, Sharma S, Firoozi S, Stephens N, Senior R, McKenna WJ (2004). The upper limit of physiological cardiac hypertrophy in elite male and female athletes: the British experience.. European Journal of Applied Physiology, 92(4-5), 592 - 597. doi:10.1007/s00421-004-1052-2
Thaman R, Gimeno JR, Reith S, Esteban MT, Limongelli G, Murphy RT, Mist B, McKenna WJ, Elliott PM (2004). Progressive left ventricular remodeling in patients with hypertrophic cardiomyopathy and severe left ventricular hypertrophy.. Journal of the American College of Cardiology, 44(2), 398 - 405. doi:10.1016/j.jacc.2004.01.054
Whyte GP, George K, Nevill A, Shave R, Sharma S, McKenna WJ (2004). Left ventricular morphology and function in female athletes: a meta-analysis.. International Journal of Sports Medicine, 25(5), 380 - 383.
Elliott P, McKenna WJ (2004). Hypertrophic cardiomyopathy.. The Lancet, 363(9424), 1881 - 1891.
Moon JC, Fisher NG, McKenna WJ, Pennell DJ (2004). Detection of apical hypertrophic cardiomyopathy by cardiovascular magnetic resonance in patients with non-diagnostic echocardiography.. Heart, 90(6), 645 - 649.
Kenton AB, Sanchez X, Coveler KJ, Makar KA, Jimenez S, Ichida F, Murphy RT, Elliott PM, McKenna W, Bowles NE, Towbin JA, Bowles KR (2004). Isolated left ventricular noncompaction is rarely caused by mutations in G4.5, alpha-dystrobrevin and FK Binding Protein-12.. Molecular Genetics and Metabolism, 82(2), 162 - 166.
Ward D, Shah JS, Tome M, Murphy RT, Elliott PM, McKenna WJ (2004). AMP kinase mutations in hypertrophic cardiomyopathy: Prevalence, penetrance, and clinical characterisation.
Pellerin D, Sharma RS, Ward D, McKenna WJ, Elliott PM (2004). Detection of myocardial hypertrophy in patients with unexplained negative T waves on ECG.
Kiotsekoglou A, Sharma RS, McKenna WJ, Elliott PM, Pellerin D (2004). Improvement of left ventricular diastolic function after septal surgical myectomy or percutaneous septal alcohol ablation in patients with hypertrophic obstructive cardiomyopathy.
Ward D, Shah JS, Tome M, McGarry K, Murphy RT, McKenna WJ, Elliott PM (2004). Left ventricular non-compaction (LVNC): Inheritance and natural history.
Kindler H, Sachdev B, Rimoldi O, Shah JS, Tome M, Lee P, McKenna WJ, Camici PG, Elliott PM (2004). Male patients with Anderson-Fabry disease (AFD) presenting with coronary microvascular dysfunction.
Kaplan SR, Gard JJ, Protonotarios N, Tsatsopoulou A, Spiliopoulou C, Anastasakis A, Squarcioni CP, McKenna WJ, Thiene G, Basso C, Brousse N, Fontaine G, Saffitz JE (2004). Remodeling of myocyte gap junctions in arrhythmogenic right ventricular cardiomyopathy due to a deletion in plakoglobin (Naxos disease).. Heart Rhythm, 1(1), 3 - 11.
Shah JS, Thaman R, Hughes D, Murphy R, Lee P, Mehta A, McKenna WJ, Elliott PM (2004). The natural history of left ventricular systolic function in Anderson Fabry's disease (AFD).
Whyte G, Stephens N, Sharma S, Shave R, Budgett R, McKenna WJ (2004). Spontaneous atrial fibrillation in a freestyle skier.. British Journal of Sports Medicine, 38(2), 230 - 232.
Basso C, Wichter T, Danieli GA, Corrado D, Czarnowska E, Fontaine G, McKenna WJ, Nava A, Protonotarios N, Antoniades L, Wlodarska K, D'Alessi F, Thiene G (2004). Arrhythmogenic right ventricular cardiomyopathy: clinical registry and database, evaluation of therapies, pathology registry, DNA banking.. European Heart Journal, 25(6), 531 - 534.
Whyte G, Stephens N, Budgett R, Sharma S, Shave RE, McKenna WJ (2004). Exercise induced neurally mediated syncope in an elite rower: a treatment dilemma.. British Journal of Sports Medicine, 38(1), 84 - 85.
Murphy RT, Mogensen J, Shaw A, Kubo T, Hughes S, McKenna WJ (2004). Novel mutation in cardiac troponin I in recessive idiopathic dilated cardiomyopathy.. The Lancet, 363(9406), 371 - 372. doi:10.1016/S0140-6736(04)15468-8
Kirschner SE, Becker E, Kubis HP, Navarro-Lopez F, Mirrakhimov MM, Osterziel KJ, McKenna W, Brenner B, Kraft T (2004). Familial hypertrophic cardiomyopathy: Point mutations in beta-MHC can increase or decrease calcium-sensitivity.
Mogensen J, Murphy RT, Kubo T, Bahl A, Moon JC, Klausen IC, Elliott PM, McKenna WJ (2004). Frequency and clinical expression of cardiac troponin I mutations in 748 consecutive families with hypertrophic cardiomyopathy. Journal of the American College of Cardiology, 44, 2315 - .

2003

Vatta M, Mohapatra B, Jimenez S, Sanchez X, Faulkner G, Perles Z, Sinagra G, Lin JH, Vu TM, Zhou Q, Bowles KR, Di Lenarda A, Schimmenti L, Fox M, Chrisco MA, Murphy RT, McKenna W, Elliott P, Bowles NE, Chen J, Valle G, Towbin JA (2003). Mutations in Cypher/ZASP in patients with dilated cardiomyopathy and left ventricular non-compaction. Journal of the American College of Cardiology, 42(11), 2014 - 2027.
Priori SG, Aliot E, Blomstrom-Lundqvist C, Bossaert L, Breithardt G, Brugada P, Camm JA, Cappato R, Cobbe SM, Di Mario C, Maron BJ, McKenna WJ, Pedersen AK, Ravens U, Schwartz PJ, Trusz-Gluza M, Vardas P, Wellens HJ, Zipes DP (2003). Update of the guidelines on sudden cardiac death of the European Society of Cardiology. European Heart Journal, 24(1), 13 - 15.
Maron BJ, McKenna WJ, Danielson GK, Kappenberger LJ, Kuhn HJ, Seidman CE, Shah PM, Spencer WH, III S, P TC, F J W, E D V, R A A, J B, E R B, B R D, P G G, G H, M A H, J S K, S L, R C L, J R O, R A P, G M S, R S T, C M W, W L J, Klein WW, Priori SG, Alonso-Garcia A, Blomstrom-Lundqvist C, De Backer G, Deckers J, Flather M, Hradec J, Oto A, Parkhomenko A, Silber S, Torbicki A (2003). American College of Cardiology/European Society of Cardiology clinical expert consensus document on hypertrophic cardiomyopathy. A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents and the European Society of Cardiology Committee for Practice Guidelines.. Journal of the American College of Cardiology, 42(9), 1687 - 1713.
Maron BJ, McKenna WJ, Danielson GK, Kappenberger LJ, Kuhn HJ, Seidman CE, Shah PM, Spencer WH, III S, P TC, F J W, E D V, R A A, J B, E R B, B R D, P G G, G H, M A H, J S K, S L, R C L, J R O, R A P, G M S, R S T, C M W, W L J, Klein WW, Priori SG, Alonso-Garcia A, Blomstrom-Lundqvist C, De Backer G, Deckers J, Flather M, Hradec J, Oto A, Parkhomenko A, Silber S, Torbicki A (2003). American College of Cardiology/European Society of Cardiology Clinical Expert Consensus Document on Hypertrophic Cardiomyopathy. A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents and the European Society of Cardiology Committee for Practice Guidelines.. European Heart Journal, 24(21), 1965 - 1991.
Behr E, Wood DA, Wright M, Syrris P, Sheppard MN, Casey A, Davies MJ, McKenna W (2003). Cardiological assessment of first-degree relatives in sudden arrhythmic death syndrome.. The Lancet, 362(9394), 1457 - 1459. doi:10.1016/S0140-6736(03)14692-2
Sharma RS, Elliott PM, McKenna WJ, Veyrat C, Pellerin D (2003). Differentiation of ischaemic and idiopathic dilated cardiomyopathy: Tissue Doppler characteristics in patients with global systolic left ventricular dysfunction.
Kiotsekoglou A, Sharma RS, McKenna WJ, Elliott PM, Pellerin D (2003). Improvement of left ventricular diastolic function after septal surgical myectomy or percutaneous septal alcohol ablation in patients with hypertrophic obstructive cardiomyopathy.
Behr ER, McKenna WJ (2003). Genetic risk for acquired arrhythmia. Trends in Genetics, 19(9), 470 - 473.
Mohapatra B, Jimenez S, Lin JH, Bowles KR, Coveler KJ, Marx JG, Chrisco MA, Murphy RT, Lurie PR, Schwartz RJ, Elliott PM, Vatta M, McKenna W, Towbin JA, Bowles NE (2003). Mutations in the muscle LIM protein and alpha-actinin-2 genes in dilated cardiomyopathy and endocardial fibroelastosis. Molecular Genetics and Metabolism, 80(1-2), 207 - 215.
Baboonian C, McKenna W (2003). Eradication of viral myocarditis: is there hope?. Journal of the American College of Cardiology, 42(3), 473 - 476.
McCrohon JA, Moon JC, Prasad SK, McKenna WJ, Lorenz CH, Coats AJ, Pennell DJ (2003). Differentiation of heart failure related to dilated cardiomyopathy and coronary artery disease using gadolinium-enhanced cardiovascular magnetic resonance. Circulation, 108(1), 54 - 59.
Sorajja P, Sweeney MG, Chalmers R, Sachdev B, Syrris P, Hanna M, Wood ND, McKenna WJ, Elliott PM (2003). Cardiac abnormalities in patients with Leber's hereditary optic neuropathy. Heart, 89(7), 791 - 792.
Thaman R, Varnava A, Hamid MS, Firoozi S, Sachdev B, Condon M, Gimeno JR, Murphy R, Elliott PM, McKenna WJ (2003). Pregnancy related complications in women with hypertrophic cardiomyopathy. Heart, 89(7), 752 - 756.
Firoozi S, Sharma S, McKenna WJ (2003). Risk of competitive sport in young athletes with heart disease. Heart, 89(7), 710 - 714.
Campbell R, Manyari DE, McKenna WJ, Frenneaux M (2003). What is the mechanism of abnormal blood pressure response on exercise in hypertrophic cardiomyopathy?. Journal of the American College of Cardiology, 41(11), 2102 - 2104.
Crilley JG, Boehm EA, Blair E, Rajagopalan B, Blamire AM, Styles P, McKenna WJ, Ostman-Smith I, Clarke K, Watkins H (2003). Hypertrophic cardiomyopathy due to sarcomeric gene mutations is characterized by impaired energy metabolism irrespective of the degree of hypertrophy. Journal of the American College of Cardiology, 41(10), 1776 - 1782.
Moon J, McKenna WJ, McCrohon JA, Elliott PM, Smith GC, Pennell DJ (2003). Toward clinical risk assessment in hypertrophic cardiomyopathy with gadolinium cardiovascular magnetic resonance. Journal of the American College of Cardiology, 41(9), 1561 - 1567. doi:10.1016/S0735-1097(03)00189-X
Mogensen J, Bahl A, Kubo T, Elanko N, Taylor R, McKenna WJ (2003). Comparison of fluorescent SSCP and denaturing HPLC analysis with direct sequencing for mutation screening in hypertrophic cardiomyopathy. Journal of Medical Genetics, 40(5), e59 - .
Firoozi S, Behr E, McKenna W (2003). Elite athletes with recurrent ERS. European Heart Journal, 24(8), 783 - 784.
Mogensen J, Bahl A, McKenna WJ (2003). Hypertrophic cardiomyopathy-the clinical challenge of managing a hereditary heart condition. European Heart Journal, 24(6), 496 - 498.
Varma C, Sharma S, Firoozi S, McKenna WJ, Daubert JC (2003). Atriobiventricular pacing improves exercise capacity in patients with heart failure and intraventricular conduction delay. Journal of the American College of Cardiology, 41(4), 582 - 588.
Mogensen J, Kubo T, Duque M, Uribe W, Shaw A, Murphy R, Gimeno JR, Elliott P, McKenna WJ (2003). Idiopathic restrictive cardiomyopathy is part of the clinical expression of cardiac troponin I mutations. Journal of Clinical Investigation, 111(2), 209 - 216. doi:10.1172/JCI200316336
Monserrat L, Elliott PM, Gimeno JR, Sharma S, Penas-Lado M, McKenna WJ (2003). Non-sustained ventricular tachycardia in hypertrophic cardiomyopathy: an independent marker of sudden death risk in young patients. Journal of the American College of Cardiology, 42, 873 - 879.
Moon J, Sachdev B, Elkington AG, McKenna WJ, Mehta A, Pennell DJ, Leed PJ, Elliott PM (2003). Gadolinium enhanced cardiovascular magnetic resonance in Anderson-Fabry disease. Evidence for a disease specific abnormality of the myocardial interstitium. European Heart Journal, 24(23), 2151 - 2155. doi:10.1016/j.ehj.2003.09.017

2002

McKenna WJ, Mogensen J, Elliott PM (2002). Role of genotyping in risk factor assessment for sudden death in hypertrophic cardiomyopathy. J Am Coll Cardiol., 39(2049), 2051 - .
McKenna WJ, Mogensen J, Elliott PM (2002). Role of genotyping in risk factor assessment for sudden death in hypertrophic cardiomyopathy [editorial].. Journal of the American College of Cardiology, 39(12), 2049 - 2051.
Niimura H, Patton KK, McKenna WJ, Soults J, Maron BJ, Seidman JG, Seidman CE (2002). Sarcomere protein gene mutations in hypertrophic cardiomyopathy of the elderly. Circulation, (105), 4 - 446.
Firoozi S, Elliott P, Sharma S, Murday A, Brecker S, Hamid M, Sachdev B, Thaman R, McKenna W (2002). Septal myotomy-myectomy and transcoronary septal alcohol ablation in hypertrophic obstructive cardiomyopathy. A comparison of clinical, haemodynamic and exercise outcomes.. European Heart Journal, 23(1617), - .
Priori SG, Aliot E, Blomstrom-Lundqvist C, Bossaert L, Breithardt G, Brugada P, Camm AJ, Cappato R, Cobbe SM, Di MC, Maron BJ, McKenna WJ, Pedersen AK, Ravens U, Schwartz PJ, Trusz-Gluza M, Vardas P, Wellens HJ, Zipes DP (2002). Task Force on Sudden Cardiac Death, European Society of Cardiology. Europace, 4(1), 3 - 18.
Priori SG, Aliot E, Blomstrom-Lundqvist C, Bossaert L, Breithardt G, Brugada P, Camm JA, Cappato R, Cobbe SM, Di M, C M, B J M, W J P, A K R, U S, P J T-G, M V, P W, H J Z, D P (2002). Task Force on Sudden Cardiac Death, European Society of Cardiology.. Italian Heart Journal, 3(S10), 1051 - 1065.
Knoll R, Hoshijima M, Hoffman HM, Person V, Lorenzen-Schmidt I, Bang ML, Hayashi T, Shiga N, Yasukawa H, Schaper W, McKenna W, Yokoyama M, Schork NJ, Omens JH, McCulloch AD, Kimura A, Gregorio CC, Poller W, Schaper J, Schultheiss HP, Chien KR (2002). The cardiac mechanical stretch sensor machinery involves a Z disc complex that is defective in a subset of human dilated cardiomyopathy.. Cell, 111(7), 943 - 955.
McKenna WJ, Behr ER (2002). Hypertrophic cardiomyopathy: management, risk stratification, and prevention of sudden death [Review]. Heart, 87(2), 169 - 176.
Matsumura Y, Elliott PM, Virdee MS, Sorajja P, Doi Y, McKenna WJ (2002). Left ventricular diastolic function assessed using Doppler tissue Imaging in Patients with Hypertrophic Cardiomyopathy: Relation to Symptoms and Exercise Capacity. Heart, 87, 247 - .
Linde C, Leclercq C, Rex S, Garrigue S, Lavergne T, Cazeau S, McKenna W, Fitzgerald M, Deharo JC, Alonso C, Walker S, Braunschweig F, Bailleul C, Daubert JC (2002). Long-term benefits of biventricular pacing in congestive heart failure: results from the MUltisite STimulation in Cardiomyopathy (MUSTIC) study.. Journal of the American College of Cardiology, 40(1), 111 - 118.
Tan RS, Behr ER, McKenna WJ, Mohiaddin RH (2002). Occult anomalous pulmonary venous drainage. The clinical value of cardiac magnetic resonance imaging. Circulation, 105, E27 - E28.
Buell HE, Stables RH, DeLong ER, Shuping KB, Killip DM, Lever HM, McKenna WJ, Rubin D, Sigwart U, Takayama M, Wagner GD, Eisenstein L, Spencer WH (2002). Percutaneous transluminal septal reduction for hypertrophic obstructive cardiomyopathy. Report from an International Pilot Study.. Journal of Medical Systems, 26(4), 293 - 300.
Sharma S, Maron BJ, Whyte G, Firoozi S, Elliott PM, McKenna WJ (2002). Physiologic limits of left ventricular hypertrophy in elite junior athletes: relevance to differential diagnosis of athlete's heart and hypertrophic cardiomyopathy. Journal of the American College of Cardiology, 16(40), 1431 - 1436.
Hamid M, Norman M, Quraishi A, Firoozi S, Thaman R, Gimeno JR, Sachdev B, Rowland E, Elliott P, McKenna WJ (2002). Prospective evaluation of relatives for familial arrhythmogenic right ventricular cardiomyopathy/ dysplasia reveals a need for broadening of the diagnostic criteria.. Journal of the American College of Cardiology, 40, 1445 - .
Hamid M, Norman M, Quraishi A, Firoozi S, Thaman R, Gimeno JR, Sachdev B, Rowland E, Elliott P, McKenna WJ (2002). Prospective evaluation of relatives for familial arrhythmogenic right ventricular cardiomyopathy/dysplasia reveals a need to broaden diagnostic criteria. Journal of the American College of Cardiology, 40(8), 1445 - 1450.
Elliott PM, Sachdev B, McKenna WJ, Takenaka T, Teraguchi H, Tei C, Lee P (2002). Prevalence of Anderson-Fabry disease in male patients with late onset hypertrophic cardiomyopathy - Reply. CIRCULATION, 106(15), E73 - E73.
Sachdev B, Takenaka T, Teraguchi H, Tei C, Lee P, McKenna WJ, Elliott PM (2002). Prevalence of Anderson-Fabry disease in male patients with late onset hypertrophic cardiomyopathy.. Circulation, 105(12), 1407 - 1411. doi:10.1161/01.CIR.0000012626.81324.38
Kohler J, Winkler G, Schulte I, Scholz T, McKenna W, Brenner B, Kraft T (2002). Mutation of the myosin converter domain alters cross-bridge elasticity.. Proceedings of the National Academy of Sciences of the United States of America, 99(6), 3557 - 3562. doi:10.1073/pnas.062415899
Mahon NG, Madden BP, Caforio ALP, Elliott PM, Haven AJ, Keogh BE, Davies MJ, McKenna WJ (2002). Immunohistologic Evidence of myocardial disease in apparently healthy relatives of patients with dilated cardiomyopathy. Journal of the American College of Cardiology, 39(3), 455 - 462. doi:10.1016/S0735-1097(01)01762-4
Mahon NG, Young JB, McKenna WJ (2002). Beta adrenergic blockers in chronic congestive cardiac failure: a call for action. European Journal of Internal Medicine, 13(2), 96 - 100.
Arad M, Benson DW, Perez-Atayde AR, McKenna WJ, Sparks EA, Kanter RJ, McGarry K, Seidman JG, Seidman CE (2002). Constitutively active AMP kinase mutations cause glycogen storage disease mimicking hypertrophic cardiomyopathy. Journal of Clinical Investigation, 109(3), 357 - 362.
Shaw T, Elliott P, McKenna W (2002). Dilated cardiomyopathy: a genetically heterogeneous disease. The Lancet, 360(9334), 654 - .
Betocchi S, Elliott PM, Briguori C, Virdee M, Losi MA, Matsumura Y, Miranda M, McKenna WJ, Chiariello M (2002). Dual chamber pacing in hypertrophic cardiomyopathy: long-term effects on diastolic function. Pacing and clinical electrophysiology, 25, 1433 - 1440.
Varma C, O'Callaghan P, Mahon NG, Hnatkova K, McKenna W, Camm AJ, Rowland E, Brecker SJD (2002). Effect of multisite pacing on ventricular coordination. Heart, 87(4), 322 - 328.
Mahon NG, Hedman AE, Padula M, Gang Y, Savelieva I, Waktare JE, Malik MM, Huikuri HV, McKenna WJ (2002). Fractal correlation properties of R-R interval dynamics in asymptomatic relatives of patients with dilated cardiomyopathy.. Journal of Heart Failure, 4(2), 151 - 158.
Ortlepp JR, Vosberg HP, Reith S, Ohme F, Mahon NG, Schroder D, Klues HG, Hanrath P, McKenna WJ (2002). Genetic polymorphisms in the renin-angiotensin-aldosterone system associated with expression of left ventricular hypertrophy in hypertrophic cardiomyopathy: a study of five polymorphic genes in a family with a disease causing mutation in the myosin binding protein C gene.. Heart., 87(3), 270 - 275.
Brown DC, Macfarlane CE, McKenna WJ, Patton MA, Dunger DB, Savage MO, Kelnar CJ (2002). Growth hormone therapy in Noonan's syndrome: non-cardiomyopathic congenital heart disease does not adversely affect growth improvement. Journal of Pediatric Endocrinology and Metabolism, 15(6), 851 - 2.

2001

Elliott P, Poloniecki J, McKenna W (2001). Sudden death and hypertrophic cardiomyopathy. The Lancet, 357(1975), 1976 - .
Elliott PM, Gimeno Blanes JR, Mahon NG, McKenna WJ (2001). Relation between severity of left-ventricular hypertrophy and prognosis in patients with hypertrophic cardiomyopathy. The Lancet, 357(9254), 420 - 424. doi:10.1016/S0140-6736(00)04005-8
Sachdev B, Takenaka T, Tel C, Lee P, McKenna WJ, Elliott PM (2001). Fabry's disease? A differential diagnosis of late onset hypertrophic cardiomyopathy?.
Priori SG, Aliot E, Blomstrom-Lundqvist C, Bossaert L, Breithardt G, Brugada P, Camm AJ, Cappato R, Cobbe SM, Di Mario C, Maron BJ, McKenna WJ, Pedersen AK, Ravens U, Schwartz PJ, Trusz-Gluza M, Vardas P, Wellens HJ, Zipes DP (2001). Task Force on Sudden Cardiac Death of the European Society of Cardiology.. European Heart Journal, 22(16), 1374 - 1450.
Varnava AM, Elliott PM, Mahon N, Davies MJ, McKenna WJ (2001). Relation between myocyte disarray and outcome in hypertrophic cardiomyopathy. The American Journal of Cardiology, 88, 275 - 279.
Syrris P, Murray A, Carter ND, McKenna W, Jeffery S (2001). Mutation detection in long QT syndrome: a comprehensive set of primers and PCR conditions. Journal of Medical Genetics, 38(10), 705 - 710.
Yi G, Poloniecki J, Dickie S, Elliott PM, Malik M, McKenna WJ (2001). Is QT dispersion associated with sudden cardiac death in patients with hypertrophic cardiomyopathy?. Annals of Noninvasive Electrocardiology, 6, 209 - 215.
Varnava AM, Elliott PM, Baboonian C, Davison F, Davies MJ, McKenna WJ (2001). Hypertrophic cardiomyopathy: histopathological features of sudden death in cardiac troponin T disease.. Circulation, 104, 1380 - 1384.
MacFarlane CE, Brown DC, Johnston LB, Patton MA, DungerD B S, M O M, W J K, J (2001). Growth hormone therapy and growth in children with Noonan's syndrome: results of 3 years' follow-up. Journal of Clinical Endocrinology and Metabolism, 86(5), 1953 - 1956.
Protonotarios N, Tsatsopoulou A, Anastasakis A, Sevdalis E, McKoy G, Stratos K, Gatzoulis K, Tentolouris K, Spiliopoulou C, Panagiotakos D, McKenna W, Toutouzas P (2001). Genotype-phenotype assessment in autosomal recessive arrhythmogenic right ventricular cardiomyopathy (Naxos disease) caused by a deletion in plakoglobin.. Journal of the American College of Cardiology, 38(5), 1477 - 1484.
Caforio ALP, Goldman JH, Baig MK, Mahon NG, Haven AJ, Souberbielle BE, Holt DW, Dalgleish AG, McKenna WJ (2001). Elevated serum levels of soluble interleukin-2 receptor, neopterin and beta-2-microglobulin in idiopathic dilated cardiomyopathy: relation to disease severity and autoimmune pathogenesis. European Journal of Heart Failure, 3(2), 155 - 163.
George K, Sharma S, Elliott PM, Batterham G, Whyte G, McKenna WJ (2001). Allometric analysis of the association between cardiac dimensions and body size variables in 464 junior athletes. Clinical Science, 100(1), 47 - 54.
Mahon NG, Zal B, Arno G, Risley P, Pinto-Basto J, McKenna WJ, Davies MJ, Baboonian C (2001). Absence of viral nucleic acids in early and late dilated cardiomyopathy. Heart, 86(6), 687 - 692.
Khogali SS, Mayosi BM, Beattie JM, McKenna WJ, Watkins H, Poulton J (2001). A common mitochondrial DNA variant associated with susceptibility to dilated cardiomyopathy in two different populations. The Lancet, 357(9264), 1265 - 1267.
Cazeau S, Leclercq C, Lavergne T, Walker S, Varma C, Linde C, Garrigue S, Kappenberger L, Haywood GA, Santini M, Bailleul C, Mabo P, Lazarus A, Ritter P, Levy T, McKenna W, Daubert JC (2001). Effects of Multisite Biventricular Pacing in Patients with Heart Failure and Intraventricular Conduction Delay.. New England Journal of Medicine, 344(12), 873 - 880.

2000

Sharma S, Elliott P, Whyte G, Jones S, Mahon N, Whipp B, McKenna WJ (2000). Utility of cardiopulmonary exercise in the assessment of clinical determinants of functional capacity in hypertrophic cardiomyopathy. The American Journal of Cardiology, 86, 162 - 168.
Sharma S, Elliott PM, Whyte G, Mahon N, Virdee MS, Mist B, McKenna WJ (2000). Utility of metabolic exercise testing in distinguishing hypertrophic cardiomyopathy from physiologic left ventricular hypertrophy in athletes. Journal of the American College of Cardiology, 36(3), 864 - 870.
Elliott PM, Poloniecki J, Dickie S, Sharma S, Monserrat L, Varnava A, Mahon N, McKenna WJ (2000). Sudden Death in Hypertrophic Cardiomyopathy: Identification of High Risk Patients.. Journal of the American College of Cardiology, 36, 2212 - 2218.
Mahon NG, Hamid S, McKenna WJ (2000). Prevalence and natural history of dilated cardiomyopathy. International Journal of Cardiology, 75(2-3), 158 - 159.
Varnava AM, Elliott PM, Sharma S, McKenna WJ, Davies MJ (2000). Hypertrophic cardiomyopathy: the interrelation of disarray, fibrosis, and small vessel disease. Heart, 84(5), 476 - 482. doi:10.1136/heart.84.5.476
Steptoe A, Mohabir A, Mahon NG, McKenna WJ (2000). Health related quality of life and psychological wellbeing in patients with dilated cardiomyopathy. Heart, 83(6), 645 - 650.
Mahon NG, Coonar AS, Jeffery S, Coccolo F, Houlston R, Akiyu J, Zal B, Baboonian C, McKenna WJ (2000). Haemochromatosis gene mutations in idiopathic dilated cardiomyopathy. Heart, 84(5), 541 - 547.
Mahon NG, McKenna WJ (2000). Genes and acquired disease. Beta-adrenoceptor polymorphisms and heart failure (editorial).. European Heart Journal, 21(22), 1810 - 1812.
Levine TB, Bernink PJ, Caspi A, Elkayam U, Geltman EM, Greenberg B, McKenna WJ, Ghali JK, Giles TD, Marmor A, Reisin LH, Ammon S, Lindberg E (2000). Effect of mibefradil, a T-type calcium channel blocker, on morbidity and mortality in moderate to severe congestive heart failure: the MACH-1 study.. Circulation, 101(7), 758 - 764.
Mahon NG, McKenna WJ (2000). Digoxin-like immunoreactive substances in hypertrophic cardiomyopathy (editorial). European Heart Journal, 21(13), 1034 - 1036.
D'Cruz LG, Baboonian C, Phillimore HE, Taylor R, Elliott PM, Varnava A, Davison FD, McKenna WJ, Carter ND (2000). Cytosine methylation confers genetic instability on cardiac troponin T in hypertrophic cardiomyopathy. Journal of Medical Genetics, 37(9), E10 - .
Gheorghiade M, Cody RJ, Francis GS, McKenna WJ, Young JB, Bonow RO (2000). Current medical therapy for advanced heart failure.. Heart Lung, 29(1), 16 - 32.
Whyte GP, George K, Sharma S, Lumley S, Gates P, Prasad K, McKenna WJ (2000). Cardiac fatigue following prolonged endurance exercise of differing distances. Medicine and Science in Sports and Exercise, 32(6), 1067 - 1072.
Yi G, Poloniecki J, Dickie S, Elliott PM, Malik M, McKenna WJ (2000). Can the assessment of dynamic QT dispersion on exercise electrocardiogram predict sudden cardiac death in hypertrophic cardiomyopathy?. Pacing and clinical electrophysiology, 23(11.2), 1953 - 1956.
Corrado D, Fontaine G, Marcus FI, McKenna WJ, Nava A, Thiene G, Wichter T (2000). Arrhythmogenic right ventricular dysplasia/cardiomyopathy: need for an international registry. Working Groups on Myocardial & Pericardial Disease and Arrhythmias of the ESC and of the Scientific Council on Cardiomyopathies of the World Heart Federation.. Journal of Cardiovascular Electrophysiology, 11(7), 827 - 832.
Moolman JA, Reith S, Uhl K, Bailey S, Gautel M, Jeschke B, Fischer C, Ochs J, McKenna WJ, Klues H, Vosberg HP (2000). A newly created splice donor site in exon 24 of the MyBP-C gene is responsible for inherited hypertrophic cardiomyopathy with incomplete disease penetrance.. Circulation, 101(12), 1396 - 1402.
Elliott PM, Mahon NG, Matsumura Y, Hawkins PN, Gillmore JD, McKenna WJ (2000). Tissue Doppler features of cardiac amyloidosis. Clinical Cardiology, 23(9), 701 - .
Mahon NG, Sharma S, Barbeyto S, Baig MK, Elliott PM, McKenna WJ (2000). Abnormal metabolic exercise parameters in relatives of patients with dilated cardiomyopathy who have left ventricular enlargement.. Heart, 83(5), 511 - 517.

1999

Choudhury L, Elliott P, Rimoldi O, Ryan M, Lammertsma AA, Boyd H, McKenna WJ, Camici PG (1999). Transmural myocardial blood flow distribution in hypertrophic cardiomyopathy.. Basic Research in Cardiology, 94, 49 - 59.
Elliott PM, Hanna MG, Ward SA, Chinnery PF, Turnbull DM, Wood NW, McKenna WJ (1999). Diagnostic utility of metabolic exercise testing in a patient with cardiovascular disease. Heart, 81(4), 441 - 443.
Varnava A, Baboonian C, Davison F, de Cruz L, Elliott PM, Davies MJ, McKenna WJ (1999). A new mutation of the cardiac troponin T gene causing familial hypertrophic cardiomyopathy without left ventricular hypertrophy.. Heart, 82, 621 - 624.
Whyte G, Sharma S, George K, McKenna WJ (1999). Alterations in cardiac morphology and function in elite multi-disciplinary athletes.. International Journal of Sports Medicine, 20(4), 222 - 226.
Maron BJ, Nishimura RA, McKenna WJ, Rakowski H, Josephson ME, Kieval RS (1999). Assessment of permanent dual-chamber pacing as a treatment for drug-refractory symptomatic patients with obstructive hypertrophic cardiomyopathy: a randomized, double-blind, crossover study (M-PATHY).. Circulation, 99, 2927 - 2933.
O'Connor CM, Gattis WA, Zannad F, McNulty SE, Gheorghiade M, Adams KF, Califf RM, McKenna WJ, Soler-Soler J, Swedberg K (1999). Beta-blocker therapy in advanced heart failure: clinical characteristics and long-term outcomes.. European Journal of Heart Failure, 1(1), 81 - 88.
O Connor CM, Gattis WA, Uretsky BF, Adams KF, McNulty SE, Grossman S, McKenna WJ, Zannad F, Swedberg K, Gheorghiade M, Califf RM, for TFIRSTI (1999). Continuous intravenous dobutamine is associated with an increased risk of death in patients with advanced heart failure: insights from the Flolan International Randomized Survival Trial (FIRST).. American Heart Journal, 138, 78 - 86.
Prasad K, Atherton J, Smith GC, McKenna WJ, Frenneaux MP, Nihoyannopoulos P (1999). Echocardiographic pitfalls in the diagnosis of hypertrophic cardiomyopathy.. Heart., 82, III8 - III15.
Sharma S, Whyte G, Elliott P, Padula M, Kaushal R, Mahon N, McKenna WJ (1999). Electrocardiographic changes in 1000 highly trained junior elite athletes. British Journal of Sports Medicine, 33, 319 - 324.
Sadoul N, de Chillou C, Aliot E, McKenna WJ (1999). Evaluation of the risk of sudden death in hypertrophic cardiomyopathy. Archives des Maladies du Coeur et des Vaisseaux, 92, 65 - 73.
Whyte GP, Sharma S, George K, McKenna WJ (1999). Exercise gas exchange responses in the differentiation of pathologic and physiologic left ventricular hypertrophy.. Medicine and Science in Sports and Exercise, 31, 1237 - 1241.
Mestroni L, Rocco C, Gregori D, Sinagra G, Di Lenarda A, Miocic S, Vatta M, Pinamonti B, Muntoni F, Caforio A, McKenna WJ, Falaschi A, Giacca M, Camerini F, and HMDSG (1999). Familial dilated cardiomyopathy: evidence for genetic and phenotypic heterogeneity.. Journal of the American College of Cardiology, 34, 181 - 190.
Adams KF, Sueta CA, Gheorghiade M, O'Connor CM, Schwartz TA, Koch GG, Uretsky B, Swedberg K, McKenna W, Soler-Soler J, Califf RM, for TFIRSTI (1999). Gender differences in survival in advanced heart failure: Insights from the FIRST Study.. Circulation, 99(14), 1816 - 1821.
Priori SG, Barhanin J, Hauer RNW, Haverkamp W, Jongsma HJ, Kleber AG, McKenna WJ, Roden DM, Rudy Y, Schwartz K, Schwartz PJ, Towbin JA, Wilde AM (1999). Genetic and molecular basis of cardiac arrhythmias: impact on clinical management part III.. Circulation, 99, 674 - 681.
Priori SG, Barhanin J, Hauer RNW, Haverkamp W, Jongsma HJ, Kleber AG, McKenna WJ, Roden DM, Rudy Y, Schwartz K, Schwartz PJ, Towbin JA, Wilde AM (1999). Genetic and molecular basis of cardiac arrhythmias: impact on clinical management.. European Heart Journal, 20(3), 174 - 195.
Mestroni L, Maisch B, McKenna WJ, Schwartz K, Charron P, Rocco C, Tesson F, Richter A, Wilke A, Komajda MOBOTCRGOTEHACMPOFDC (1999). Guidelines for the study of familial dilated cardiomyopathies.. European Heart Journal, 20, 93 - 102.
Elliott PM, D Cruz L, McKenna WJ (1999). Late-Onset Hypertrophic Cardiomyopathy Caused by a Mutation in the Cardiac Troponin T Gene. New England Journal of Medicine, 341, 1855 - 1856.
Batterham AM, George KP, Whyte G, Sharma S, McKenna W (1999). Scaling cardiac structural data by body dimensions: a review of theory, practice, and problems.. International Journal of Sports Medicine, 20(8), 495 - 502.
Gadler F, Linde C, Daubert C, McKenna W, Meisel E, Aliot E, Chojnowska L, Guize M, Gras D, Jeanrenaud X, Kappenberger L, for TPICSG (1999). Significant improvement of quality of life following atrioventricular synchronous pacing in patients with hypertrophic obstructive cardiomyopathy - Data from 1 year of follow-up.. European Heart Journal, 20, 1044 - 1050.
Elliott PM, Sharma S, Varnava A, Poloniecki J, Rowland E, McKenna WJ (1999). Survival after cardiac arrest or sustained ventricular tachycardia in patients with hypertrophic cardiomyopathy.. Journal of the American College of Cardiology, 33, 1596 - 1601.
Choudhury L, Elliott P, Rimoldi O, Ryan M, Lammertsma AA, Boyd H, McKenna WJ, Camici PG (1999). Transmural myocardial blood flow distribution in hypertrophic cardiomyopathy and effect of therapy. Basic Research in Cardiology, 94, 49 - 59.

1998

Mattu RK, Needham EWA, Richter D, Soccio M, Elliott PM, McKenna WJ (1998). The atrial natriuretic peptide gene as a disease modifier in hypertrophic cardiomyopathy. European Heart Journal, 19, 606 - .
Englund A, Hnatkova K, Kulakowski P, Elliott PM, Malik M, McKenna WJ (1998). Use of spectral turbulence analysis for the identification of patients at high risk for ventricular fibrillation and sudden death in patients with hypertrophic cardiomyopathy.. Cardiology, 90, 79 - 82.
Yi G, Elliott PM, McKenna WJ, Prasad K, Sharma S, Guo XH, Camm AJ, Malik M (1998). QT dispersion and risk factors for sudden death in patients with hypertrophic cardiomyopathy.. The American Journal of Cardiology, 82(12), 1514 - 1519.
Niimura H, Bachinski LL, Sangwatanaroj S, Watkins H, Chudley AE, McKenna W, Kristinsson A, Roberts R, Sole M, Maron B, Seidman JG, Seidman CE (1998). Mutations in the gene for cardiac myosin-binding protein C and late-onset familial hypertrophic cardiomyopathy. New England Journal of Medicine, 338(18), 1248 - 1257.
McKenna WJ, Coccolo F, Elliott PM (1998). Genes and disease expression in hypertrophic cardiomyopathy (Commentary).. The Lancet, 352, 1162 - 1163.
Coonar AS, Protonotarios N, Tsatsopoulou A, Needham EWA, Houlston RS, Cliff S, Otter MI, Murday VA, Mattu RK, McKenna WJ (1998). Gene for arrhythmogenic right ventricular cardiomyopathy with diffuse nonepidermolytic palmoplantar keratoderma and woolly hair (Naxos disease) maps to 17q21.. Circulation, 97(20), 2049 - 2058.
Baig MK, Goldman JH, Caforio ALP, A S K, P J M, W J (1998). Familial dilated cardiomyopathy: cardiac abnormalities are common in asymptomatic relatives and may represent early disease.. Journal of the American College of Cardiology, 31(1), 195 - 201.
Yamada M, Elliott PM, Kaski JC, Prasad K, Gane JN, Lowe CM, Doi Y, McKenna WJ (1998). Dipyridamole stress thallium-201 perfusion abnormalities in patients with hypertrophic cardiomyopathy. Relationship to clinical presentation and outcome. European Heart Journal, 19, 500 - 507.
Elliott PM, Brecker SJ, McKenna WJ (1998). Diastolic dysfunction in hypertrophic cardiomyopathy (Editorial). European Heart Journal, 19, 1125 - 1127.
McKenna WJ, Elliott PE (1998). Diagnostic criteria in hypertrophic cardiomyopathy - another paradigm shift (Editorial). European Heart Journal, (19), 539 - 540.
Lorenzoni R, Gistri R, Cecchi F, Olivotto C, G E, P M, W J C, P G (1998). Coronary vasodilator reserve is impaired in patients with hypertrophic cardiomyopathy and left ventricular dysfunction. The American Journal of Cardiology, 136, 972 - 981.
Jones S, Elliott PM, Sharma S, McKenna WJ, Whipp B (1998). Cardiopulmonary response to exercise in patients with hypertrophic cardiomyopathy. Heart, 80, 60 - 67.
Currie PF, Goldman JH, Caforio ALP, Jacob AJ, Baig MK, Brettle RP, Haven AJ, Boon NA, McKenna WJ (1998). Cardiac autoimmunity in HIV related heart muscle disease.. Heart, 79(6), 599 - 604.
Englund A, Hnatkova K, Elliott PM, McKenna WJ, Malik M (1998). Wavelet decomposition analysis of the signal averaged electrocardiogram used for risk stratification of patients with hypertrophic cardiomyopathy. European Heart Journal, 19, 1383 - 90.
Thomson HL, Morris-Thurgood J, Atherton J, McKenna W J F, M P (1998). Reflex responses of venous capacitance vessels in patients with hypertrophic cardiomyopathy.. Clinical Science, 94(4), 339 - 346.

1997

Yi G, Keeling PJ, Hnatkova K, Goldman JH, Malik M, McKenna WJ (1997). Usefulness of signal-averaged electrocardiography in evaluation of idiopathic-dilated cardiomyopathy in families.. The American Journal of Cardiology, 79, 1203 - 1207.
Lorenzoni R, Gistri R, Cecchi F, Olivotto I, Chiriatti G, Elliott P, McKenna WJ, Camici PG (1997). Syncope and ventricular arrhythmias in hypertrophic cardiomyopathy are not related to the derangement of coronary microvascular function.. European Heart Journal, 18, 1946 - 1950.
Sharma S, Whyte G, McKenna WJ (1997). Sudden death from cardiovascular disease in young athletes: fact or fiction?. British Journal of Sports Medicine, 31(4), 269 - 276.
Corrado D, Basso C, Thiene G, McKenna WJ, Davies MJ, Fontaliran F, Nava A, Silvestri F, Blomstrom-Lundqvist C, Wlodarska EK, Fontaine G, Camerini F (1997). Spectrum of clinicopathologic manifestations arrhythmogenic right ventricular cardiomyopathy / dysplasia: a multicenter study.. Journal of the American College of Cardiology, 30(6), 1512 - 1520.
Sadoul N, Prasad K, Elliott PM, Bannerjee S, Frenneaux MP, McKenna WJ (1997). Sadoul N, Prasad K, Elliott PM, Bannerjee S, Frenneaux MP, McKenna WJ.. Circulation, 96, 2987 - 2991.
Laversuch CJ, Seo H, Modarres H, Collins DA, McKenna W, Bourke BE (1997). Reduction in heart rate variability in patients with systemic lupus erythematosus.. Journal of Rheumatology, 24, 1540 - 1544.
Caforio ALP, Baboonian C, McKenna WJ (1997). Postviral autoimmune heart disease - fact or fiction? (Clinical Perspective). European Heart Journal, 18(7), 1051 - 1055.
Kappenberger L, Linde C, Daubert C, McKenna W, Meisel E, Sadoul N, Chojnowska L, Guize L, Gras D, Jeanrenaud X, Ryden L, and TPICSG (1997). Pacing in hypertrophic obstructive cardiomyopathy. A randomized crossover study.. European Heart Journal, 18(8), 1249 - 1256.
Spirito P, Seidman CE, McKenna WJ, Maron BJ (1997). Management of hypertrophic cardiomyopathy [Review]. New England Journal of Medicine, 336, 775 - 785.
Bromelow KV, Souberbielle B, Alavi A, Goldman JH, Libera LD, Dalgleish AG, McKenna WJ (1997). Lack of T cell response to cardiac myosin and a reduced response to PPD in patients with idiopathic dilated cardiomyopathy. Journal of Autoimmunity, 10, 219 - 227.
Crook JR, Goldman JH, Dalziel M, Madden B, McKenna WJ (1997). Increased ventricular sialylation in patients with heart failure secondary to ischemic heart disease. Clinical Cardiology, 20(5), 455 - 458.
McKenna WJ, Spirito P, Desnos M, Dubourg O, Komajda M (1997). Experience from clinical genetics in hypertrophic cardiomyopathy: proposal for new diagnostic criteria in adult members of affected families.. Heart, 77, 130 - 132.
Cox S, O'Donoghue AC, McKenna WJ, Steptoe A (1997). Health related quality of life and psychological wellbeing in patients with hypertrophic cardiomyopathy. Heart, 78(2), 182 - 187.
Yi G, Goldman JH, Keeling PJ, Reardon M, McKenna WJ, Malik M (1997). Heart rate variability in idiopathic dilated cardiomyopathy: relation to disease severity and prognosis.. Heart, 77, 108 - 114.
Momiyama Y, Hartikainen J, Nagayoshi H, Albrecht P, Kautzner J, Saumarez RC, McKenna WJ, Camm AJ (1997). Exercise-induced T-Wave alternans as a marker of high risk in patients with hypertrophic cardiomyopathy. Japanese Circulation Journal, 61(8), 650 - 656.
Califf RM, Adams KF, McKenna WJ, Gheorghiade M, Uretsky BF, McNulty SE, Darius H, Schulman K, Zannad F, Handberg-Thurmond E, Harrell FEJ, Wheeler W, Soler-Soler J, Swedberg K (1997). A randomized controlled trial of epoprostenol therapy for severe congestive heart failure: The Flolan International Randomized Survival Trial (FIRST). American Heart Journal, 134, 44 - 54.
Thompson CH, Kemp GJ, Taylor DJ, Conway M, Rajagopalan B, O Donoghue A, Styles P, McKenna WJ, Radda GK (1997). Abnormal skeletal muscle bioenergetics in familial hypertrophic cardiomyopathy. Heart, 78, 177 - 181.
Montgomery HE, Clarkson P, Dollery CM, Prasad K, Losi MM, Hemingway H, Statters D, Jubb M, Girvain M, Varnava A, World M, Deanfield J, Talmud P, McEwan JR, McKenna WJ, Humphries S (1997). Association of angiotensin converting enzyme gene I/D polymorphism with change in left ventricular mass in response to physical training. Circulation, 96, 741 - 747.
Caforio ALP, Goldman JH, Haven AJ, Baig KM, Dalla Libera L, McKenna WJ, and TMTTI (1997). Circulating cardiac-specific autoantibodies as markers of autoimmunity in clinical and biopsy-proven myocarditis.. European Heart Journal, 18, 270 - 275.
Lee PJ, Deanfield JE, Burch M, Baig K, McKenna WJ, Leonard JV (1997). Comparison of the functional significance of left ventricular hypertrophy in hypertrophic cardiomyopathy and glycogenosis Type III. The American Journal of Cardiology, 79, 834 - 838.
Hossein-Nia M, Baig K, Goldman JH, Keeling PJ, Caforio AL, Holt DW, McKenna WJ (1997). Creatine kinase isoforms as circulating markers of deterioration in idiopathic dilated cardiomyopathy. Clinical Cardiology, 20, 55 - 60.

1995

PRASAD K, MONTGOMERY H, FREDERICKS S, MOULT J, CLARKSON P, DOLLERY C, WORLD M, STATTERS D, HOLT D, MCKENNA WJ (1995). RIGOROUS PHYSICAL-TRAINING ALTERS BRAIN NATRIURETIC PEPTIDE LEVELS IN HEALTHY-YOUNG MALES. CIRCULATION, 92(8), 2239 - 2239.
MONTGOMERY HE, KEELING PJ, GOLDMAN JH, HUMPHRIES SE, TALMUD PJ, MCKENNA WJ (1995). LACK OF ASSOCIATION BETWEEN THE INSERTION DELETION POLYMORPHISM OF THE ANGIOTENSIN-CONVERTING ENZYME GENE AND IDIOPATHIC DILATED CARDIOMYOPATHY. J AM COLL CARDIOL, 25(7), 1627 - 1631.

Preston LC, Lipscomb S, Robinson P, Mogensen J, McKenna WJ, Watkins H, Ashley CC, Redwood CS (). Functional Effects of the Novel Dilated Cardiomyopathy-Causing Mutation Gly159Asp in Cardiac Troponin C in skinned muscle fibres.. Cardiovascular Research, , - .
Behr EJ, Sheppard M, Wright M, Bowker TJ, Davies MJ, McKenna WJ, Wood DA (). Sudden Arrhythmic Death Syndrome (SADS) - a national survey of sudden unexplained cardiac death.. Heart, , - .
Limongelli G, Hawkes L, Calabro R, McKenna WJ, Syrris P (). Mutation screening of the PTPN11 gene in hypertrophic cardiomyopathy.. European Journal of Medical Genetics, , - .

UCL DIVISION OF MEDICINE

UCL Division of Medicine

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Prof William Mckenna

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