Medical physics

Brian Hutton

Schematic of SPECT insert for a preclinical SPECT/MRI system. Similar modules will be used in designing a system for brain SPECT which can be used as an insert to MRI or as a standalone mobile system. The clinical prototype will be installed at UCL for evaluation in patients with glioma.

The UCL Medical Physics Group undertakes basic research related to Nuclear Medicine and Multimodality Imaging. This currently encompasses a range of projects including design of novel SPECT systems, development of new reconstruction algorithms and development of image analysis techniques that aim to reduce artefacts and improve quantification. The group is largely dependent on external funding through grants (EPSRC, EC, CRUK) and industrial collaboration (Spectrum Dynamics, Siemens, GE, GSK). The group has joint research projects with the UCL Centre for Medical Image Computing with several individuals there now working on Nuclear Medicine related projects (along with Professor Simon Arridge and Dr Sebastien Ourselin). The group attracts many visiting scientists (most recently Kathleen Vunckx from Belgium and Filipa Costa & Debora Salvado from Portugal). Regular INM Physics seminars are organised, open to scientists in the London region. Recent publications include reviews on SPECT scatter correction and partial volume correction. Current research directions include exploitation of the unique capabilities of simultaneous PET/MRI (joint UCL & Siemens support) and development of a SPECT insert suitable for SPECT/MRI (EC FP7 grant with Milan Polytechnic, Mediso and others).

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