MEDCG003 Drug Discovery 1

Module Title
MEDCG003 Drug Discovery 1
Module Value
30
Term
Term 1
Short Description Students will be introduced to the preclinical phases of drug development. Sessions will be held on choice of drug target, chemical approaches to developing therapeutic molecules, use of animal models, toxicology and first-into man studies.  This module is designed to cover drug development up to the first clinical trial phases.  Teaching will involve input from our industrial partner, GlaxoSmithKline.
Module Aims and Objectives
  • review the process of drug discovery and development from a clinical and industry perspective
  • understand the concept of target based and model based drug discovery/development
  • explore the use of animal and computer modelling of disease
  • understand the importance of chemistry to all aspects of the drug discovery process
  • discuss the ethics of drug discovery and clinical trials
  • review phase I, II and III studies
  • review the regulation of drug development and marketing
  • understand clinical trial design and interpretation
 Topics
  • Formulating a scientific question
  • Modelling diseases
  • First into man - Principle, history
  • First into man - patients
  • Surrogate Markers in Clinical Trials
  • Chemistry
  • Clinical Trial Design
  • Risk and toxicology
  • Regulation
  • Industry perspective - Model based Drug Discovery
  • Genome
Assessment details
  • Unseen 3 hour examination (100%)
  • Non-assessed Group Presentation and Learning Journal
 Module Tutor
Dr Simon Yona

Page last modified on 17 jun 14 15:31