Centre for Cardiovascular Biology and Medicine
Cardiovascular Biology and Medicine is part of the Division of Medicine
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Medicine News

Wellcome Trust Strategic Award in Functional Neuromics

Published: Jul 27, 2015 11:56:12 AM

Improving Treatment for Systemic Amyloidosis

Published: Jul 20, 2015 3:05:08 PM

UCL/Rosetrees Interdisciplinary Symposium - 22nd October 2015

Published: Jul 15, 2015 4:18:43 PM

Research

Centre for Cardiovascular Biology and Medicine

Professor Ian Zachary’s research, supported by major funding by the British Heart Foundation and the European Union (FP7), investigates how the essential angiogenic factor, Vascular Endothelial Growth Factor (VEGF), signals endothelial cells to form new blood vessels, with major interests in. signalling involved in endothelial cell migration, and the role of Neuropilin-1.

These questions are addressed using diverse techniques in cell and molecular biology and in vivo zebrafish and genetically altered mutant mice models.

A major part of our translational research, led by Professor John Martin, is the use of stem cells for treating heart disease.

The Centre received the first grant awarded by the UK Stem Cell Foundation to perform a clinical trial of autologous stem cells and repair of the heart immediately after a heart attack. If successful, this trial may have a considerable impact on NHS practice in the treatment of heart attack patients.



Dr Paul Frankel’s group combines molecular analysis of cell signalling required for cancer cell motility with state-of-the-art imaging technologies - particularly optical projection tomography and fluorescence-based biosensors – using novel zebrafish models of cancer. 

Dr Richard Day leads the Applied Biomedical Engineering Group, focussing on interdisciplinary research and regenerative medicine for debilitating conditions including incontinence, visual impairment, muscular dystrophy and cardiovascular disease as part of the UCL Grand Challenge of Human Wellbeing.