Cells entering mitosis undergo adhesion disassembly, osmotic changes and membrane remodelling, which contribute to mitotic rounding. At the same time actin filaments are cross linked to the membrane increasing cell mechanical rigidity, and microtubules become shorter and highly dynamic compared to interphase, allowing for the search and capture of chromosomes and the formation of the mitotic spindle. Then, by following intracellular and extracellular cues, motor proteins anchored at the membrane control the spindle position and orientation, which in turn allow for precise control over symmetry and orientation of cell division. In my work, I explore the role of the actomyosin-dependent mitotic cell rounding in ensuring efficient spindle assembly, and symmetric spindle positioning.