The mission of the Laboratory for Molecular Cell biology and Cell Biology Unit (LMCB/CBU) is to understand the molecular basis of cell function and behaviour relevant to human disease. Cells are the fundamental unit of life and cell biology lies at heart of contemporary biomedical research. A fully integrated knowledge of how cells work under normal conditions and what goes awry in disease situations is essential for developing novel therapeutic strategies.
New technologies are making it possible to understand fundamental properties of cells at unparalleled resolution, making cell biology one of the most exciting, dynamic and challenging areas of science. Although many of the basic principles of cell organisation and function have been established, the details remain obscure. Recent technical developments, in particular in imaging, have brought a range of new tools to cell biologists that allow cell processes to be analysed at significantly higher resolution, in terms of both biochemical complexity and spatial and dynamic organisation. One aim of cell biologists over the next 10 years will be to use these advances to build a more complete understanding of normal cell organisation, dynamics and regulation, how these processes are perturbed under different disease conditions, and what pathways and targets might be best exploited for rational drug design.