Jamie is working on the regulatory control of autophagy. He is focussing on the role of kinases and phosphatases in activating or repressing autophagy protease ATG4B using RNAi-mediated knockdown in cell-based assays.

Janos is developing image analysis tools for high-content screening of three-dimensional culture systems. He aims to identify small molecule inhibitors of autophagy in 3D model systems.