Electron microscopy publications


Weston S,
Czieso S, White IJ, Smith SE, Kellam
P, Marsh M. A membrane topology model for human interferon inducible
transmembrane protein 1. PLoS One. 2014 Aug 8;9(8)

Kajita M,
Sugimura K, Ohoka A, Burden J,
Suganuma H, Ikegawa M, Shimada T, Kitamura T, Shindoh M, Ishikawa S, Yamamoto
S, Saitoh S, Yako Y, Takahashi R, Okajima T, Kikuta J, Maijima Y, Ishii M, Tada
M, Fujita Y. Filamin acts as a key regulator in epithelial defence against
transformed cells. Nat Commun. 2014 Jul 31;5:4428.

Marra V, Burden JJ, Crawford F, Staras K.
Ultrastructural readout of functional synaptic vesicle pools in hippocampal
slices based on FM dye labeling and photoconversion. Nat Protoc. 2014

Ferraro F,
Kriston-Vizi J, Metcalf DJ, Martin-Martin B, Freeman J, Burden JJ, Westmoreland D, Dyer CE, Knight AE, Ketteler R, Cutler
DF. A two-tier Golgi-based control of organelle size underpins the functional
plasticity of endothelial cells. Dev Cell. 2014 May 12;29(3):292-304



Ribeiro S,
Napoli I, White IJ, Parrinello S,
Flanagan AM, Suter U, Parada LF, Lloyd AC. Injury signals cooperate with Nf1
loss to relieve the tumour-suppressive environment of adult peripheral nerve. Cell
Rep. 2013 Oct 17;5(1):126-36

Fuchs C,
Abitbol K, Burden JJ, Mercer A,
Brown L, Iball J, Anne Stephenson F, Thomson AM, Jovanovic JN. GABAA receptors
can initiate the formation of functional inhibitory GABAergic synapses. Eur J
Neurosci. 2013 Oct;38(8):3146-58.



Marra V, Burden JJ, Thorpe JR, Smith IT, Smith
SL, Häusser M, Branco T, Staras K.  A preferentially segregated recycling vesicle pool of limited
size supports neurotransmission in native central synapses. Neuron. 2012 Nov

Orenbuch A,
Shalev L, Marra V, Sinai I, Lavy Y, Kahn J, Burden JJ, Staras K, Gitler D. Synapsin selectively controls the
mobility of resting pool vesicles at hippocampal terminals. J Neurosci. 2012
Mar 21;32(12):3969-80.

A, Marra V, Bush D, Burden JJ,
Branco T, Staras K. Recruitment of resting vesicles into recycling pools
supports NMDA receptor-dependent synaptic potentiation in cultured hippocampal
neurons. J Physiol. 2012 Apr 1;590(Pt 7):1585-97.

Napoli I,
Noon LA, Ribeiro S, Kerai AP, Parrinello S, Rosenberg LH, Collins MJ, Harrisingh
MC, White IJ, Woodhoo A, Lloyd AC. A central role for the ERK-signaling
pathway in controlling Schwann cell plasticity and peripheral nerve
regeneration in vivo. Neuron. 2012 Feb 23;73(4):729-42.           



N, Letellier M, White IJ, Goda Y. Differential
control of presynaptic efficacy by postsynaptic N-cadherin and β-catenin Nat
Neurosci. 2011 Dec 4;15(1):81-9.

Nightingale TD, White IJ, Doyle EL,
Turmaine M, Harrison-Lavoie KJ, Webb KF, Cramer LP, Cutler DF.  Actomyosin II contractility expels von
Willebrand factor from Weibel-Palade bodies during exocytosis.  J Cell Biol. 2011 Aug 22;194(4):613-29.

C, Jing J, Wu C, Matern H, Schaack J, Burden
and Prekeris R. Interaction
between FIP5 and S_X18 Regulates Epithelial Lumen Formation. Journal of Cell
Biology 2011

Llobet A,
Gallop J, Burden J, Camdere G,
Chandra P, Vallis Y, Hopkins C, Lagnado L, and McMahon H. Endophilin Drives the
Fast Mode of Vesicle Retrieval in a Ribbon Synapse. Journal of Neuroscience 2011
Jun 8: 8512-9.

Henry AG, White IJ, Marsh M, von Zastrow M,
Hislop JN. The role of ubiquitination in lysosomal trafficking of ∂-opioid
receptors. Traffic. 2011 Feb;12(2):170-84.



Jing J,
Junutula JR, Wu C, Burden J, Matern
H, Peden AA, Prekeris R. FIP1/RCP  binding
to Golgin-97 regulates retrograde transport from recycling endosomes to the
trans-Golgi network. Mol Biol Cell. 2010 Sep;21(17):3041-53.

Pears MR,
Codlin S, Haines RL, White IJ,
Mortishire-Smith RJ, Mole SE, Griffin JL. Deletion of btn1, an orthologue of
CLN3, increases glycolysis and perturbs amino acid metabolism in the fission
yeast model of Batten disease. Mol Biosyst.  2010 Jun 18;6(6):1093-102

Staras K,
Branco T, Burden JJ, Pozo K, Darcy
K, Marra V, Ratnayaka A, Goda Y.  A
vesicle superpool spans multiple presynaptic terminals in hippocampal neurons.
Neuron. 2010 Apr 15;66(1):37-44.

Eden ER, White IJ, Tsapara A, Futter CE.
Membrane contacts between endosomes and ER provide sites for PTP1B-epidermal
growth factor receptor interaction. Nat Cell Biol. 2010 Mar;12(3):267-72.



Georgiou M,
Marinari E, Burden J, Baum B. Cdc42,
Par6, and aPKC regulate Arp2/3-mediated endocytosis to control local adherens
junction stability. Curr Biol. 2008 Nov 11;18(21):1631-8.

E, Wilson GM, Burden J, Hopkins CR,
Anderson K, Goldenring JR, Prekeris R. The Rip11/Rab11-FIP5 and kinesin II
complex regulates endocytic protein recycling. J Cell Sci. 2008 Nov 15;121(Pt

Codlin S,
Haines RL, Burden JJ, Mole SE. Btn1
affects cytokinesis and cell-wall deposition by independent mechanisms, one of
which is linked to dysregulation of vacuole pH. J Cell Sci. 2008 Sep 1;121(Pt

Silva EA, Burden J, Franc NC. In vivo and in
vitro methods for studying apoptotic cell engulfment in Drosophila. Methods
Enzymol. 2008;446:39-59.



E, Au-Yeung HW, Van Goethem E, Burden J,
Franc NC. Requirement
for a Drosophila E3-ubiquitin ligase in phagocytosis of apoptotic cells.
Immunity. 2007 Oct;27(4):585-96.

Zenner HL, Collinson LM, Michaux G, Cutler DF.
High-pressure freezing provides insights into Weibel-Palade body biogenesis. J
Cell Sci. 2007 Jun 15;120(Pt 12):2117-25.



Darcy KJ,
Staras K, Collinson LM, Goda Y. An
ultrastructural readout of fluorescence recovery after photobleaching using
correlative light and electron microscopy. Nat Protoc. 2006;1(2):988-94.

KJ, Michaux G, Hewlett L, Kaur J,
Hannah MJ, Lui-Roberts WW, Norman KE, Cutler DF. P-selectin and CD63 use
different mechanisms for delivery to Weibel-Palade bodies. Traffic. 2006

Darcy KJ,
Staras K, Collinson LM, Goda Y.
Constitutive sharing of recycling synaptic vesicles between presynaptic
boutons. Nat Neurosci. 2006 Mar;9(3):315-21.

Millán J, Hewlett L, Glyn M, Toomre D, Clark P,
Ridley AJ. Lymphocyte transcellular migration occurs through recruitment of
endothelial ICAM-1 to caveola- and F-actin-rich domains. Nat Cell Biol. 2006

Michaux G,
Abbitt KB, Collinson LM, Haberichter
SL, Norman KE, Cutler DF. The  physiological
function of von Willebrand's factor depends on its tubular storage in
endothelial Weibel-Palade bodies. Dev Cell. 2006 Feb;10(2):223-32.

N, Goberdhan DC, Collinson L, Fujita
Y, Cox IM, Wilson C, Pichaud F. Regulated and polarized PtdIns(3,4,5)P3 accumulation is essential for
apical membrane morphogenesis in photoreceptor epithelial cells. Curr Biol.
2006 Jan 24;16(2):140-9.



WW, Collinson LM, Hewlett LJ, Michaux G, Cutler DF. An AP-1/clathrin
coat plays a novel and essential role in forming the Weibel-Palade  bodies of endothelial cells. J Cell
Biol. 2005 Aug 15;170(4):627-36.

Garcia E,
Pion M, Pelchen-Matthews A, Collinson L,
Arrighi JF, Blot G, Leuba F, Escola JM, Demaurex N, Marsh M, Piguet V. HIV-1
trafficking to the dendritic cell-T-cell infectious synapse uses a pathway of
tetraspanin sorting to the immunological synapse. Traffic. 2005

Signoret N,
Hewlett L, Wavre S, Pelchen-Matthews
A, Oppermann M, Marsh M. Agonist-induced endocytosis of CC chemokine receptor 5
is clathrin dependent. Mol Biol Cell. 2005 Feb;16(2):902-17.



Burnett C,
Makridou P, Hewlett L, Howard K.
Lipid phosphate phosphatases dimerise, but this interaction is not required for
in vivo activity. BMC Biochem. 2004 Jan 16;5:2.



M, Takeuchi Y, Hewlett L, Collins M.
Murine leukemia virus particle  assembly
quantitated by fluorescence microscopy: role of Gag-Gag interactions and membrane
association. J Virol. 2003 Nov;77(21):11651-60.

Hannah MJ,
Hume AN, Arribas M, Williams R, Hewlett
, Seabra MC, Cutler DF. Weibel-Palade bodies recruit Rab27 by a
content-driven, maturation-dependent mechanism that is independent of cell
type. J Cell Sci. 2003 Oct 1;116(Pt 19):3939-48.

Michaux G, Hewlett LJ, Messenger SL, Goodeve AC,
Peake IR, Daly ME, Cutler DF. Analysis of intracellular storage and regulated
secretion of 3 von Willebrand disease-causing variants of von Willebrand
factor. Blood. 2003 Oct 1;102(7):2452-8.



Hannah MJ,
Williams R, Kaur J, Hewlett LJ,
Cutler DF. Biogenesis of Weibel-Palade bodies. Semin Cell Dev Biol. 2002

JO, Simpson N, Hewlett L, Hall A.
Rac regulates endothelial morphogenesis and capillary assembly. Mol Biol Cell.
2002 Jul;13(7):2474-85.