Our research is focused on the development of experimental technology to study biological processes that fall outside of the resolving power of conventional cell biology studies. We specially focus on applications to super-resolution (SR) microscopy. SR is non-trivial and requires a multidisciplinary approach for its development and application. Additionally, a novel realm of analytical and modelling tools needs to be established to resolve the new level of information retrieved from cellular structure and behaviour at the nanoscale. Together with collaborators we have tackled some of these challenges, developing fundamental technologies ranging the areas of optical microscopy, quantitative image analysis, photoswitchable fluorescence and the analysis of molecular territories within cells.
These same principles seed and guide our research group. Both training and bringing together specialised scientists in the fields of cell biology, physics, applied mathematics, optics, and computer science, unified by with the common desire to apply their expertise into the study of biological systems. The group is set in a highly cooperative environment, with a large percentage of its emphasis directed into developing super-resolution technology and applying it to biological research.